' 
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Total Carbohydrate
<1g
<1%†
Calcium (from calcium magnesium phytate)
131 mg
10%
Phosphorus (from calcium magnesium phytate)
192 mg
15%
Magnesium (from calcium magnesium phytate)
40 mg
10%
IP-6 (inositol hexaphosphate) (from calcium magnesium phytate)
800 mg
**
Inositol
220 mg
**
Maitake Mushroom Extract standardized to 30% pure D-fraction (9 mg)
30 mg
**
Cat's Claw Extract (bark) standardized to 4% alkaloids (0.4 mg)
10 mg
**
The product is found useful for the following medical conditions
Cancer
SCIENTIFIC SCORE
Possibly Effective
Based on 33 Researches
7.9
USERS' SCORE
Good
Based on 29 Reviews
8.9
9
Myo-inositol affects prostate cancer cells
Proteomic Analysis of Anticancer Effect of Myo-inositol in Human Prostate Cancer (DU-145) Cell Line.
Most Relevant Research
We investigated the potential benefits of Myo-inositol, a naturally occurring sugar alcohol, on DU-145 prostate cancer cells. By treating these cancer cells with various doses of Myo-inositol, we determined its half-maximal inhibitory concentration (IC50) using a simple method that measures cell viability.
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
Our findings revealed that Myo-inositol significantly decreased the viability of DU-145 cells, showing an IC50 of 0.06 mg/ml. This suggests that Myo-inositol may effectively inhibit cancer cell growth.
Furthermore, we performed a detailed proteomic analysis using advanced techniques to explore how Myo-inositol changes protein expression. We found notable differences in protein levels between treated and untreated cells, particularly in areas linked to key cellular functions like cytoskeletal regulation, apoptosis (cell death), and stress responses. For instance, certain proteins tied to tumor suppression were upregulated in response to Myo-inositol treatment.
Overall, these observations highlight Myo-inositol's potential as a therapeutic option. However, further studies are necessary to unravel the underlying mechanisms and assess its effectiveness in combination with other treatments for managing prostate cancer, especially castration-resistant prostate cancer (CRPC).
9.5
Remission success
Most Useful Review
READ THIS—MAX3 HELPS KILL GLIOBLASTOMA BRAIN CANCER. This product has put my Mum in remission from glioblastoma brain cancer! With MAX3, MSM, Frankincense pills, and black seed oil, her MRIs have been clear! This cancer was deemed a death sentence, yet here she is happily wearing her beautiful wigs. I have been advised to make her "eat" this all day. Her immune system is functioning exceptionally well and combating cancer. I firmly believe this product, among others, has kept her healthy and alive. While she is undergoing chemotherapy and radiation treatments, she occasionally feels a bit "run down".
Lung Cancer
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.3
USERS' SCORE
Good
Based on 4 Reviews
8.7
9
IP shows potential in lung cancer
Intrathecal pemetrexed improves survival outcomes in previously treated EGFR-mutant advanced non-small-cell lung cancer with leptomeningeal metastases.
Most Relevant Research
We explored the effects of intrathecal pemetrexed (IP) on lung cancer patients facing leptomeningeal metastases (LM), particularly after they had not responded to previous treatments with EGFR-TKIs. The study analyzed 50 patients who received a 50 mg dose of IP after their cancer progressed, looking closely at their clinical responses and survival outcomes over two years.
Remarkably, we observed a 64% clinical response rate, indicating that many patients saw improvements in their neurological symptoms and overall performance. The median intracranial progression-free survival was 5.3 months, while overall survival reached up to 12 months for these patients. Those who responded positively to the treatment experienced significantly longer survival compared to non-responders, which is encouraging for both patients and doctors seeking options after traditional therapies fail.
The treatment was generally well tolerated, with manageable side effects mostly related to myelosuppression and liver functions. Additionally, genetic testing revealed consistency between the tumors and the cerebrospinal fluid, which opens up further investigation into the underlying mechanisms of treatment resistance. Overall, our findings suggest that IP could be a promising option for patients battling advanced lung cancer with LM after existing therapies have stopped working.
Remarkably, we observed a 64% clinical response rate, indicating that many patients saw improvements in their neurological symptoms and overall performance. The median intracranial progression-free survival was 5.3 months, while overall survival reached up to 12 months for these patients. Those who responded positively to the treatment experienced significantly longer survival compared to non-responders, which is encouraging for both patients and doctors seeking options after traditional therapies fail.
The treatment was generally well tolerated, with manageable side effects mostly related to myelosuppression and liver functions. Additionally, genetic testing revealed consistency between the tumors and the cerebrospinal fluid, which opens up further investigation into the underlying mechanisms of treatment resistance. Overall, our findings suggest that IP could be a promising option for patients battling advanced lung cancer with LM after existing therapies have stopped working.
9.5
Notable improvement
Most Useful Review
Last July, my small dog, 9 years old, was diagnosed with lung cancer and given only 4 months to live without treatment. She struggled to breathe, with frequent gagging. Chemotherapy nearly killed her, and it seemed metastasis had begun during treatment. After starting her on Max3 and a grain-free diet, I noticed a marked improvement. Over 10 months later, she is thriving, gagging just once each morning. Unfortunately, my local store switched to a less convenient version of my supplement, but I ordered the original online. I feel this change impacted effectiveness, so I supplemented it with immune boosters.
Autoimmune Disorder
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6
USERS' SCORE
Good
Based on 2 Reviews
8.6
7
Cat's claw shows potential benefits
Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis.
Most Relevant Research
We explored the effectiveness of cat's claw in managing autoimmune disorders, specifically osteoarthritis (OA) and rheumatoid arthritis (RA). Our review included various studies, focusing on its potential as a dietary supplement to reduce inflammation and oxidative stress associated with these conditions.
From the research, we found three studies that support the use of cat's claw, whether alone or in combination with other treatments, for patients suffering from OA. However, while some evidence exists, we noted that the effectiveness of cat's claw for RA isn't as robust.
It's important to recognize, though, that the full impact of cat's claw on autoimmune disorders needs more thorough research. Many factors, including varying responses to treatment, call for caution in making solid recommendations based solely on the existing studies.
Overall, while there’s promise in using cat's claw for managing autoimmune conditions, we should approach it with realistic expectations and an understanding that further investigation is necessary before solid conclusions can be drawn.
From the research, we found three studies that support the use of cat's claw, whether alone or in combination with other treatments, for patients suffering from OA. However, while some evidence exists, we noted that the effectiveness of cat's claw for RA isn't as robust.
It's important to recognize, though, that the full impact of cat's claw on autoimmune disorders needs more thorough research. Many factors, including varying responses to treatment, call for caution in making solid recommendations based solely on the existing studies.
Overall, while there’s promise in using cat's claw for managing autoimmune conditions, we should approach it with realistic expectations and an understanding that further investigation is necessary before solid conclusions can be drawn.
8.8
Supports recovery
Most Useful Review
I have been taking Cell Forte MAX3 for a few months after being diagnosed with an autoimmune disorder and starting chemotherapy and immunotherapy. I feel that MAX3 has helped keep my body fit during this process. The product seems to be of good quality, and I believe it has benefitted me alongside a balanced diet. I am on my second batch and will reorder more.
Chronic Cough
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Effective treatment
Most Useful Review
The medication is effective. The child became unwell with a cough producing phlegm, and this treatment helped to manage it excellently.
Chronic Fatigue Syndrome
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Improved energy levels
Most Useful Review
I highly recommend this product. Since contracting Covid-19, I experienced unstable blood sugar, dizziness, and fatigue, feeling colder than usual. I discovered that IP6 could stabilise various bodily systems, and this formula, enriched with immune-boosting mushrooms, has significantly improved my condition. Within just two days of using it, my energy has restored by more than half from my previous state of chronic fatigue syndrome. I'm incredibly grateful to iHerb for offering such a remarkable product.
Common Cold
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 11 Reviews
8.6
9.5
Relieves cold symptoms
Most Useful Review
I truly like this product and take it regularly for myself and a friend. It effectively alleviates cold symptoms and speeds up recovery without causing drowsiness or other unpleasant side effects. At the first signs of illness, I increase my dose and return to the usual amount the next day. I feel it enhances my immunity. All in all, good health!
Ear Infection
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Boosts immune function
Most Useful Review
This product is truly excellent for enhancing immune function. It’s a staple in my natural medicine cabinet, and I’ve successfully used it to reduce an ear infection linked to a tooth abscess.
Pneumonia
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Effective pneumonia remedy
Most Useful Review
AWESOME! I have been taking this product since 2001 when I had pneumonia and struggled to recover. My chiropractor recommended it, and I felt better almost immediately. Now, whenever I sense something coming on, I take it straight away, and the symptoms vanish within hours. This works brilliantly and is a superb alternative to antibiotics.
Whooping Cough
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Effective treatment
Most Useful Review
The medication worked well. My child fell ill with a cough and phlegm, but this helped them recover perfectly from whooping cough.
Bronchitis
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 1 Review
8.6
8
Inositol's role in bronchitis unclear
[On mechanisms underlying bronchial obstruction in chronic dust bronchitis in workers of deep coal mines].
Most Relevant Research
We explored how inositol levels might influence bronchitis in workers exposed to coal dust. The study observed that healthy miners had elevated levels of lysophosphatidyl choline and phosphatidyl inositol. This suggests that the metabolism of phosphatidyl inositol could lead to increased cytoplasmic calcium, which may cause bronchial muscle contraction and contribute to bronchial obstruction.
Interestingly, patients with dust bronchitis responded positively to oral choline chloride solutions, which seemed to reduce bronchospasms. These patients also had lower serum subunits of phosphatidyl inositol and higher levels of phosphatidyl choline. While there is a clear connection to choline chloride treatment, the isolated effect of inositol specifically on bronchitis symptoms isn't fully established.
Overall, the findings hint at a complex interplay between these compounds in managing bronchial issues, but further research would be needed to clarify inositol's direct role.
Interestingly, patients with dust bronchitis responded positively to oral choline chloride solutions, which seemed to reduce bronchospasms. These patients also had lower serum subunits of phosphatidyl inositol and higher levels of phosphatidyl choline. While there is a clear connection to choline chloride treatment, the isolated effect of inositol specifically on bronchitis symptoms isn't fully established.
Overall, the findings hint at a complex interplay between these compounds in managing bronchial issues, but further research would be needed to clarify inositol's direct role.
9.5
Increased energy
Most Useful Review
Upon receiving this, I took one immediately and felt an increase in energy within minutes, no longer feeling exhausted. The next day, I took two in the morning and noticed improved concentration and no afternoon slump. After work, I took two more and had such high energy that I walked three miles! My joints were pain-free, and my lungs felt clearer than they have in a long time (having struggled with bronchitis) and my heart murmur remained stable. This supplement is fantastic and I will continue to buy it!
Flu
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.6
9.5
Immune system boost
Most Useful Review
I highly recommend this product as it greatly boosted my immune system. I've been around numerous individuals with flu and colds, yet it hasn't affected me at all.
Ovarian Cancer
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
10
Cancer remission
Most Useful Review
This is a remarkable product. My sister had stage 3 ovarian cancer and used this product; she no longer has cancer. My cousin also had a lump in her chest, and after taking this product, the lump disappeared.
Acne
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 1 Review
8.5
9
Myo-inositol improves acne symptoms
Efficacy of myo-inositol in the treatment of cutaneous disorders in young women with polycystic ovary syndrome.
Most Relevant Research
We explored the effects of myo-inositol (MYO) on acne among young women diagnosed with polycystic ovary syndrome (PCOS). The study included 50 participants who underwent treatment with MYO for six months, focusing on its potential to improve the often frustrating skin issues linked to PCOS.
At the beginning and after the treatment period, we measured various factors including levels of hormones and insulin, as well as the severity of acne.
Remarkably, after three months of MYO therapy, we observed significant reductions in hormone levels associated with PCOS, particularly testosterone and insulin. After six months, both hirsutism and acne symptoms showed notable improvement among the participants.
This research highlights MYO as a promising, safe treatment option for alleviating acne symptoms in individuals with PCOS. Its ability to improve metabolic conditions while managing acne is a fascinating development for women seeking effective solutions for their skin concerns.
At the beginning and after the treatment period, we measured various factors including levels of hormones and insulin, as well as the severity of acne.
Remarkably, after three months of MYO therapy, we observed significant reductions in hormone levels associated with PCOS, particularly testosterone and insulin. After six months, both hirsutism and acne symptoms showed notable improvement among the participants.
This research highlights MYO as a promising, safe treatment option for alleviating acne symptoms in individuals with PCOS. Its ability to improve metabolic conditions while managing acne is a fascinating development for women seeking effective solutions for their skin concerns.
8
Effective acne treatment
Most Useful Review
Perfectly, it proved to be quite effective. An excellent support for my immune system at the cellular level. Initially, I experienced a flare-up of some kind of infection, with subcutaneous acne appearing, but soon everything returned to normal.
Brain Tumor
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.5
8
Maitake-polysaccharide enhances apoptosis
Induction Effect to Apoptosis by Maitake Polysaccharide: Synergistic Effect of Its Combination With Vitamin C in Neuroglioma Cell.
Most Relevant Research
We set out to understand how maitake mushroom polysaccharide (MP), when combined with vitamin C (VC), affects brain tumor cells, specifically in human neuroglioma M059 K cells. Through our study, we found that using a combination of MP and VC led to a significant reduction in cell viability—about 53.10%. This indicates that these compounds together may weaken the tumor cells' ability to survive.
Our findings also showed that this combination treatment caused cell cycle arrest at the G2/M phase, meaning that it effectively stopped the cells from proceeding through their natural life cycle. Notably, we observed that 38.54% of the treated cells went through apoptosis, a form of programmed cell death critical for eliminating cancerous cells.
We noted changes in proteins associated with apoptosis, showing upregulation of Bax and caspase-3, while Bcl-2 levels decreased. Additionally, there was an increase in the activities of caspase-3, caspase-8, and caspase-9. These observations suggest that the anticancer effects we witnessed likely stem from the induction of apoptosis triggered by the combined treatment of MP and VC.
Our findings also showed that this combination treatment caused cell cycle arrest at the G2/M phase, meaning that it effectively stopped the cells from proceeding through their natural life cycle. Notably, we observed that 38.54% of the treated cells went through apoptosis, a form of programmed cell death critical for eliminating cancerous cells.
We noted changes in proteins associated with apoptosis, showing upregulation of Bax and caspase-3, while Bcl-2 levels decreased. Additionally, there was an increase in the activities of caspase-3, caspase-8, and caspase-9. These observations suggest that the anticancer effects we witnessed likely stem from the induction of apoptosis triggered by the combined treatment of MP and VC.
8.8
Improved condition
Most Useful Review
I purchased this for my elderly dog, who I suspect has a brain tumour. After suffering from epilepsy and being unable to move, she experienced incontinence. This treatment has made her feel much better after a week, and for over half a month she has been like her old self again. I recommend taking one tablet in the morning and evening for treatment, and one tablet each time for maintenance.
Breast Cancer
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Maitake polysaccharide shows cancer potential
Polysaccharide isolated from eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T cells responses.
Most Relevant Research
We investigated how a fungal polysaccharide extracted from maitake mushrooms can impact breast cancer. This treatment approach focuses on myeloid-derived suppressor cells, or MDSCs, which are known to help tumors grow by suppressing the immune response in cancer patients.
Our findings revealed that the maitake polysaccharide, referred to as GFI, significantly reduces the number of MDSCs in the bloodstream and tumor tissue in mice, resulting in slower tumor growth. Interestingly, GFI particularly targets a subset of MDSCs known as PMN-MDSCs, while leaving another type, M-MDSCs, largely unaffected.
We also observed that GFI not only clears out these immune suppressing cells but also revives and activates CD8 T cells, which are crucial for attacking tumors. This dual action enhances the body's natural defenses against cancer, suggesting that GFI could serve as a promising treatment option for breast cancer patients.
Altogether, our study sheds light on an innovative approach to battling breast cancer, further emphasizing the potential of natural compounds derived from mushrooms in cancer therapy.
Our findings revealed that the maitake polysaccharide, referred to as GFI, significantly reduces the number of MDSCs in the bloodstream and tumor tissue in mice, resulting in slower tumor growth. Interestingly, GFI particularly targets a subset of MDSCs known as PMN-MDSCs, while leaving another type, M-MDSCs, largely unaffected.
We also observed that GFI not only clears out these immune suppressing cells but also revives and activates CD8 T cells, which are crucial for attacking tumors. This dual action enhances the body's natural defenses against cancer, suggesting that GFI could serve as a promising treatment option for breast cancer patients.
Altogether, our study sheds light on an innovative approach to battling breast cancer, further emphasizing the potential of natural compounds derived from mushrooms in cancer therapy.
8.8
Supports immune system
Most Useful Review
I purchase this product for my mum, a breast cancer survivor at 86. It effectively builds her immune system and keeps her strong. I truly love it!
Dizziness
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Improved energy levels
Most Useful Review
I highly recommend this newly discovered treasure. After contracting Covid, my blood sugar became unstable, leading to dizziness and fatigue. I even felt cold washing my hands in normal water. I soon realised that IP6 stabilises various body systems, and with its immune-boosting mushroom ingredients, I felt significantly better within just two days. My energy has improved by more than half compared to before I was infected. Thank you, iHerb, for providing such a fantastic product!
Epilepsy
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.8
USERS' SCORE
Good
Based on 1 Review
8.5
9
Inositol shows promise in epilepsy
Preventing epileptogenesis by interaction between inositol isomers and proteins.
Most Relevant Research
We explored the potential of inositol, a group of naturally occurring compounds, in preventing epilepsy, particularly in the context of seizures caused by kainic acid. Our study involved a careful examination of three types of inositol—myo-inositol (MI), scyllo-inositol (SCI), and D-chiro-inositol (DCHI)—to see how they might help manage the condition.
We induced status epilepticus in rats using kainic acid and then treated these animals with MI, SCI, DCHI, or a saline solution over a 28-day period. Throughout eight weeks of monitoring, we meticulously recorded behavioral patterns, including spontaneous recurrent seizures and how these compounds affected spatial learning and memory deficits related to epilepsy.
The results were promising. We observed that all three inositol isomers positively influenced seizure frequency and duration, as well as cognitive impairments associated with epileptogenesis. This suggests that inositols may interact with proteins relevant to various biological pathways, showcasing their potential as antiepileptogenic agents.
Overall, our findings indicate that inositols could pave the way for new approaches in epilepsy treatment, particularly in preventing the onset of the condition. While further research is necessary, this study lays important groundwork for understanding how these compounds might benefit those affected by epilepsy.
We induced status epilepticus in rats using kainic acid and then treated these animals with MI, SCI, DCHI, or a saline solution over a 28-day period. Throughout eight weeks of monitoring, we meticulously recorded behavioral patterns, including spontaneous recurrent seizures and how these compounds affected spatial learning and memory deficits related to epilepsy.
The results were promising. We observed that all three inositol isomers positively influenced seizure frequency and duration, as well as cognitive impairments associated with epileptogenesis. This suggests that inositols may interact with proteins relevant to various biological pathways, showcasing their potential as antiepileptogenic agents.
Overall, our findings indicate that inositols could pave the way for new approaches in epilepsy treatment, particularly in preventing the onset of the condition. While further research is necessary, this study lays important groundwork for understanding how these compounds might benefit those affected by epilepsy.
8.8
Improved condition
Most Useful Review
I purchased this for my elderly dog, whom I suspect has a brain tumour. After suffering from epilepsy, she struggled to move independently following medication, leading to incontinence. After a week on this treatment, she began to improve, and for over a fortnight, she resembled her healthier self. The recommendation is to take one tablet in the morning and evening for treatment, and one tablet each time for maintenance.
High Cholesterol
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.4
USERS' SCORE
Good
Based on 1 Review
8.5
9
Maitake mushrooms reduce cholesterol levels
Grifola frondosa polysaccharides ameliorate lipid metabolic disorders and gut microbiota dysbiosis in high-fat diet fed rats.
Most Relevant Research
We explored how polysaccharides derived from maitake mushrooms, known scientifically as Grifola frondosa, can influence high cholesterol and other lipid issues. This study focused on rats fed a high-fat diet, a common model for examining metabolic disorders.
By administering these mushroom polysaccharides, we observed a remarkable decrease in levels of total triglycerides, cholesterol, and free fatty acids in the rats' blood. Additionally, liver fat accumulation was notably reduced, highlighting the potential of maitake mushrooms to combat fat buildup in the body.
Furthermore, we noted an increase in bile acid excretion among the rats receiving the mushroom treatment. This finding suggests that maitake may help improve cholesterol processing by promoting the removal of fats from the liver.
The research also identified changes in the gut microbiota among the treated rats, as certain beneficial bacteria flourished while harmful ones declined. This shift aligns with improved lipid metabolism, hinting at a complex relationship between our gut health and cholesterol levels.
It was evident that the consumption of maitake mushrooms could lead to positive changes in lipid profiles, making them an appealing option for those seeking natural ways to manage cholesterol and prevent hyperlipidemia.
By administering these mushroom polysaccharides, we observed a remarkable decrease in levels of total triglycerides, cholesterol, and free fatty acids in the rats' blood. Additionally, liver fat accumulation was notably reduced, highlighting the potential of maitake mushrooms to combat fat buildup in the body.
Furthermore, we noted an increase in bile acid excretion among the rats receiving the mushroom treatment. This finding suggests that maitake may help improve cholesterol processing by promoting the removal of fats from the liver.
The research also identified changes in the gut microbiota among the treated rats, as certain beneficial bacteria flourished while harmful ones declined. This shift aligns with improved lipid metabolism, hinting at a complex relationship between our gut health and cholesterol levels.
It was evident that the consumption of maitake mushrooms could lead to positive changes in lipid profiles, making them an appealing option for those seeking natural ways to manage cholesterol and prevent hyperlipidemia.
8
Effective treatment
Most Useful Review
I believe that Nature's Way products are more effective than IP6 Gold. This is my second review of IP6 products; I have previously used Nature's Way. High ferritin is quite troubling for me, as it once exceeded 800 and I also have fatty liver. Despite trying numerous liver-protecting products and exercising, I had little success. I read on Xiaohongshu about someone whose ferritin normalised after eight months on this product, which inspired me to try it. Initially, my ferritin was 791.55, but after two months of using Nature's Way, it reduced to 657.69. I am pleased with the results and my determination to continue has strengthened. Additionally, my liver function tests improved significantly. After switching to IP6 Gold, my ferritin dropped to 604.91 after three months, but the decline has slowed. I intend to return to Nature's Way for another three months for comparison.
Liver Disease
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Maitake improves diabetes-related liver health
Anti-diabetic effect of an alpha-glucan from fruit body of maitake (Grifola frondosa) on KK-Ay mice.
Most Relevant Research
We evaluated the impact of an alpha-glucan extracted from maitake mushrooms on mice with a model of type 2 diabetes. This study specifically focused on various health markers related to liver function and diabetes.
By administering two different doses of the maitake mushroom extract, we observed significant improvements across several measures in diabetic mice. The treatment led to reductions in body weight, fasting blood sugar levels, and harmful substances like triglycerides and cholesterol.
Notably, we found that liver functions improved as evidenced by increased levels of beneficial substances like glycogen and reduced oxidative stress markers. Additionally, we observed enhanced insulin sensitivity, which is crucial for managing diabetes effectively.
These findings suggest that maitake mushrooms may offer tangible benefits not only for diabetes management but specifically for protecting and improving liver health in affected individuals.
By administering two different doses of the maitake mushroom extract, we observed significant improvements across several measures in diabetic mice. The treatment led to reductions in body weight, fasting blood sugar levels, and harmful substances like triglycerides and cholesterol.
Notably, we found that liver functions improved as evidenced by increased levels of beneficial substances like glycogen and reduced oxidative stress markers. Additionally, we observed enhanced insulin sensitivity, which is crucial for managing diabetes effectively.
These findings suggest that maitake mushrooms may offer tangible benefits not only for diabetes management but specifically for protecting and improving liver health in affected individuals.
8.8
Ferritin reduction
Most Useful Review
I initially used Nature's Way products for high ferritin levels, which were concerning due to my fatty liver. After two months on the product, my ferritin significantly decreased, and my liver function tests also improved, surprising me. I later tried IP6 Gold, but the decrease in ferritin became much slower. I plan to return to Nature's Way to see if the results can be replicated.
Reflux
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Assists reflux relief
Most Useful Review
This product helps with my reflux.
Chemotherapy
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Boosted immune response
Most Useful Review
I absolutely love this product. It works deeply to enhance my immune system. It was instrumental while I was recuperating from chemotherapy.
Cold
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.5
USERS' SCORE
Good
Based on 7 Reviews
8.5
8
Inositol enhances rapeseed cold tolerance
Inositol Improves Cold Tolerance Through Inhibiting and Increasing Ca Influx in Rapeseed ( L.).
Most Relevant Research
We explored the impact of inositol on cold stress in rapeseed, an essential oilseed crop affected by low temperatures. Notably, we found that inositol plays a significant role in enhancing cold tolerance in these plants by boosting calcium ion (Ca) influx.
Our study involved identifying various genes associated with inositol and analyzing their expression under cold conditions. Interestingly, inositol appeared to inhibit the expression of calcineurin B-like genes, which are involved in regulating calcium flow, suggesting a unique pathway through which inositol aids in cold resilience.
Additionally, when we overexpressed certain genes linked to calcium flux, we noted a stronger response to cold stress, further emphasizing the importance of the inositol-Ca pathway in facilitating cold tolerance in rapeseed. These findings not only deepen our understanding of how rapeseed copes with cold conditions but also present a potential strategy for enhancing crop resilience in the face of climate challenges.
Our study involved identifying various genes associated with inositol and analyzing their expression under cold conditions. Interestingly, inositol appeared to inhibit the expression of calcineurin B-like genes, which are involved in regulating calcium flow, suggesting a unique pathway through which inositol aids in cold resilience.
Additionally, when we overexpressed certain genes linked to calcium flux, we noted a stronger response to cold stress, further emphasizing the importance of the inositol-Ca pathway in facilitating cold tolerance in rapeseed. These findings not only deepen our understanding of how rapeseed copes with cold conditions but also present a potential strategy for enhancing crop resilience in the face of climate challenges.
8.8
Light colds only
Most Useful Review
Don’t let any cold get you down. I have read many reviews but this product truly deserves high praise. When I sense a cold coming on, I start taking it as per the instructions, which makes the cold feel light. Sometimes, I forget I even had a cold when I neglect to take it. It’s a standard item in my home and for my loved ones.
Prostate Cancer
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.6
USERS' SCORE
Good
Based on 1 Review
8.5
9
IP6 potentially prevents prostate cancer
Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model.
Most Relevant Research
We evaluated how inositol hexaphosphate (IP6), a natural compound found in various foods, influences the growth and development of prostate cancer in a special group of mice known as TRAMP. The study involved feeding these male mice either regular water or water containing 2% IP6 at different stages of their growth – starting at 4, 12, 20, and 30 weeks of age – for a period of about 8 to 15 weeks.
Pathological evaluations at the end of the study revealed some encouraging results. The IP6 treatment seemed to halt tumor progression earlier on, and it significantly reduced the incidence of more severe forms of the disease by around 55% to 70%. This finding suggests that IP6 could have a crucial role in preventing prostate cancer from advancing in severity.
Furthermore, we explored the effects of IP6 on cancer stem cells (CSCs), a small group of cells within tumors that can drive cancer growth. The results indicated that IP6 might help in reducing these CSCs in prostate tumors. In laboratory tests, we also found that IP6 treatment dramatically decreased the number of floating prostate cancer stem cell clusters by approximately 90%.
Overall, these findings suggest that IP6 holds significant promise as a preventive measure against prostate cancer, particularly at earlier stages of the disease.
Pathological evaluations at the end of the study revealed some encouraging results. The IP6 treatment seemed to halt tumor progression earlier on, and it significantly reduced the incidence of more severe forms of the disease by around 55% to 70%. This finding suggests that IP6 could have a crucial role in preventing prostate cancer from advancing in severity.
Furthermore, we explored the effects of IP6 on cancer stem cells (CSCs), a small group of cells within tumors that can drive cancer growth. The results indicated that IP6 might help in reducing these CSCs in prostate tumors. In laboratory tests, we also found that IP6 treatment dramatically decreased the number of floating prostate cancer stem cell clusters by approximately 90%.
Overall, these findings suggest that IP6 holds significant promise as a preventive measure against prostate cancer, particularly at earlier stages of the disease.
8.8
Enhances immune system
Most Useful Review
Great find on Amazon! I have been using this product for about four years since my diagnosis of prostate cancer. It aims to enhance the body's natural killer cells. Normally, I purchase it from a local health store, but this seller has saved me some money with convenient home delivery. I wish Amazon would implement an "Auto-Fill" ordering programme for it.
Skin Cancer
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Effective immune support.
Most Useful Review
I purchased "cell forte max 3" for a friend with uterine cancer. He has been in remission for years, and it supports immune function and helps against various cancers, including skin cancer. I highly recommend it for building resilience against illness.
Ulcer
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.5
8
SNF472 shows promise for ulcers
Improvement in wound healing, pain, and quality of life after 12 weeks of SNF472 treatment: a phase 2 open-label study of patients with calciphylaxis.
Most Relevant Research
We explored the effects of SNF472, an intravenous treatment derived from myo-inositol hexaphosphate, on patients suffering from calciphylaxis, a condition often marked by painful, necrotic skin ulcers. Our study involved fourteen patients who were already receiving standard care and thrice-weekly hemodialysis. Over a 12-week period, these patients received SNF472 three times a week, allowing us to assess its potential benefits on wound healing, pain relief, and overall quality of life.
Assessments used included the Bates-Jensen Wound Assessment Tool for measuring wound healing, a visual analog scale for pain, and a specific quality of life questionnaire focused on wound healing. The results were promising: we observed significant improvements in wound healing, with reductions in pain and enhancements in quality of life. Notably, more than half of the patients who started with ulcerated lesions showed an improvement by the end of the study.
The treatment was well tolerated, with no serious adverse events directly linked to SNF472. Most side effects were typical for hemodialysis patients and were not considered treatment-related. These positive findings suggest that SNF472 could be a viable new option for managing the challenging symptoms of calciphylaxis, paving the way for future randomized trials to confirm its efficacy.
Assessments used included the Bates-Jensen Wound Assessment Tool for measuring wound healing, a visual analog scale for pain, and a specific quality of life questionnaire focused on wound healing. The results were promising: we observed significant improvements in wound healing, with reductions in pain and enhancements in quality of life. Notably, more than half of the patients who started with ulcerated lesions showed an improvement by the end of the study.
The treatment was well tolerated, with no serious adverse events directly linked to SNF472. Most side effects were typical for hemodialysis patients and were not considered treatment-related. These positive findings suggest that SNF472 could be a viable new option for managing the challenging symptoms of calciphylaxis, paving the way for future randomized trials to confirm its efficacy.
8
Supports healing process
Most Useful Review
Although my Bullmastiff has lymphoma, he experiences no pain. I've been giving him this product for about a year to assist with healing his occasional skin ulcers on his feet, and increasing the dosage has proven effective. I believe this product has significantly contributed to his well-being and survival despite his diagnosis.
Cold Sores
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.2
4.8
Less effective treatment
Most Useful Review
Has its effectiveness diminished? Previously, if I took this at the onset of a cold, I felt better right away. However, this time, it didn't help me recover.
Allergies
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 1 Review
8
8
Maitake mushrooms may alleviate allergies
extract and ergosterol reduce allergic reactions in an allergy mouse model by suppressing the degranulation of mast cells.
Most Relevant Research
We explored the potential of maitake mushroom extracts in combating allergies, focusing on their effects on mast cells, which play a key role in allergic reactions. Our study specifically examined the impact of the mushroom extract, GFE, and its active component, ergosterol, on allergic responses in a mouse model.
Through a well-structured air pouch-type allergic inflammation model, we observed that both GFE and ergosterol significantly inhibited the degranulation of mast cells. This is a critical process where mast cells release compounds that cause allergic symptoms.
Notably, our findings revealed that GFE and ergosterol effectively alleviated anaphylactic responses in these mice. This suggests that maitake mushrooms could offer a promising, natural approach to reducing allergic reactions by targeting mast cell degranulation, making it a potential novel functional food for allergy prevention.
Through a well-structured air pouch-type allergic inflammation model, we observed that both GFE and ergosterol significantly inhibited the degranulation of mast cells. This is a critical process where mast cells release compounds that cause allergic symptoms.
Notably, our findings revealed that GFE and ergosterol effectively alleviated anaphylactic responses in these mice. This suggests that maitake mushrooms could offer a promising, natural approach to reducing allergic reactions by targeting mast cell degranulation, making it a potential novel functional food for allergy prevention.
3.5
No significant improvement
Most Useful Review
I am a bit disappointed. I’ve almost finished one bottle, but there has been no significant improvement in my skin allergies.
Headache
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8
3.5
Possible herx reaction
Most Useful Review
I'm uncertain due to only using it for 2 days. I felt extremely tired after the first dose, which was pleasant for my insomnia, but I woke with a headache. After taking a total of four doses, I experienced ongoing fatigue, headaches, and body aches. While I plan to continue using it, I shall reduce the dosage to see if I feel better, as I've read that Cats Claw may cause such reactions.
