Supplement Facts
Serving Size:   1 Capsule
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
33.3 mg 
37%
Vitamin D (as D3 Cholecalciferol)
8.3 mcg (333 IU)
42%
Calcium (Elemental)(from Microcrystalline Hydroxyapatite)
333.3 mg 
26%
Magnesium (as Magnesium Oxide)
116.7 mg 
28%
Zinc (as Zinc L-Methionine Sulfate)
3.3 mg 
30%
Copper (as Copper Gluconate)
0.333 mg 
37%
Manganese (as Manganese Citrate)
0.333 mg
14%
Vitamin K2 (as Natural MK-7 [Menaquinone-7]) 
15 mcg
Boron (as Boron Citrate)
1 mg

The product is found useful for the following medical conditions

Osteoporosis details

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
USERS' SCORE
Good
Based on 51 Reviews
8.7
We examined how hyperoside, a compound in Semen cuscutae, can combat osteoporosis in ovariectomized mice, particularly after menopause. The study revealed that hyperoside effectively increased bone density and improved bone structure by reducing the differentiation of osteoclasts—cells that break down bone.

Our findings indicated that the anti-osteoporotic effects of hyperoside are linked to the estrogen receptor α, as blocking this receptor reversed its benefits. Ultimately, hyperoside shows promise in protecting against osteoporosis through its actions on specific signaling pathways.
9
Normalised density
Most Useful Review
381 people found this helpful
I reversed osteopenia! I have taken Bone-Up by Jarrow Formulas for years after being diagnosed with osteopenia. I committed to taking it daily; my osteopenia eventually reversed, and my bone density is now normal. I engage in regular weight-bearing exercise which supports bone health. Despite previous thinning bone loss, I was able to reverse it through determination and consistent use of Jarrow Bone-Up. I won’t stop taking this for life!

Cancer details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.6
9
Improved bone density
Most Useful Review
109 people found this helpful
Turned my osteoporosis to osteopenia in two years. I am a 21-year breast cancer survivor aged 55. I had surgery, chemotherapy, radiation, and Tamoxifen before menopause, which can weaken bones. Although I maintained a healthy diet and exercised regularly, I was shocked to discover I had osteoporosis at 53. I researched treatment options and was wary of medications due to their side effects. I opted for Bone-Up supplements, taking two capsules three times a day, and increased my Vitamin D intake. I’m pleased to report my scores have improved, and I feel that these changes have made a significant difference.

Menopause details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.5
9
Effective for joints
Most Useful Review
25 people found this helpful
My review will be of interest to women aged 45+ seeking support for their joints and bones. I bought this complex a couple of years ago on my doctor's advice. Initially, I attributed its positive effects to collagen, but I later realised my mistake. After purchasing a large jar of Bone-Up, I noticed a reduction in joint crunching and back pain within 2.5-3 weeks. This complex really works! The ingredients are impressive, including Calcium Hydroxyapatite, derived from bovine bone, alongside essential vitamins and minerals for better absorption. It serves as excellent support during menopause. I highly recommend it! I take 2 capsules daily with meals. If my review has helped, please give it a like! 👍 Cheers to happy shopping!😉

Pelvic Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.5
9
Bone pain relief
Most Useful Review
This is my third time using this supplement. During menopause, I experience bone pain, and this product alleviates the stiffness effectively. Its balanced composition covers my calcium needs, and the quality of ingredients is good. The taste is neutral, and I genuinely recommend it.

Autoimmune Disorder details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.3
7.5
Supports calcium needs
Most Useful Review
2 people found this helpful
I order this for my mother, who has an autoimmune disorder and needs calcium constantly, especially while taking Metipred. Her indicators are good, and she continues taking the complex. Three capsules are preferable for her than six due to the sheer number of medications she takes daily. However, we need to supplement with extra vitamins, which we monitor through tests.

Knee Pain details

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 35 Reviews
8.1
We examined the effectiveness of the Missouri Osteochondral Preservation System (MOPS) compared to standard preservation methods for treating knee pain after osteochondral allograft (OCA) transplantation.

Our study revealed that patients receiving MOPS shell grafts experienced significant improvements in pain and function after two years.

Specifically, MOPS showed an impressive 98% functional graft survival rate, contrasted with 83% for standard methods.

Moreover, unipolar patella allograft patients reported the greatest relief and functionality, indicating that MOPS may offer superior short-term outcomes for knee pain.
7.5
Reduced knee pain
Most Useful Review
25 people found this helpful
My review is for women over 45 seeking a joint and bone complex. After using Bone-Up alongside collagen, I noticed a decrease in joint crunching and back pain after 2.5-3 weeks. The composition is excellent, with Calcium Hydroxyapatite and supporting vitamins. It is fantastic for menopause. I highly recommend it, taking 2 capsules daily with meals.

Leg Cramps details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 9 Reviews
8.1
9
Cramp relief
Most Useful Review
6 people found this helpful
Helped with leg cramps. My friend suffered such severe leg cramps that she cried at night. I gave her some of these to try and the cramps entirely disappeared—until she ran out. Then they returned. I believe the 2:1 Calcium: Magnesium ratio helped her, along with the added Vitamin C for absorption. I usually take four caps with a multi-vitamin and Evening Primrose Oil.

Bone Pain details

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 84 Reviews
8
We evaluated the impact of complementary medicine on the side-effects of hormone therapy in prostate cancer patients. In a study of 93 patients experiencing severe side-effects, we utilized sodium selenite, plant enzymes, and Lc-lectin. Over 50 days, we documented noticeable reductions in bone pain and other side-effects. Specifically, bone pain severity decreased significantly from a score of 4.74 to 2.82. This suggests that complementary treatments can be beneficial in managing hormone therapy side-effects.
10
Pain relief solution
Most Useful Review
17 people found this helpful
I purchased this product following a recommendation from a nutritionist owing to my osteopenia. Within weeks, it completely alleviated the hip pain I was experiencing. I lead an active lifestyle and wish to reverse the damage done by genetics and family history of osteoporosis. I plan to continue taking this product as long as needed and even advised my brother-in-law, who experienced similar relief. You really don’t have to suffer!

Back Pain details

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.9
We conducted a double-blind, randomized trial to see how well the Bushen Huoxue Formula (BSHXF) works for discogenic low-back pain. Seventy patients received either BSHXF or a placebo alongside lumbar traction for three weeks.

Our results showed that those taking BSHXF experienced significantly less pain and better mobility compared to the control group. Notably, their improvement in function and muscle tone was maintained even one to three months after treatment, with no adverse effects reported.

This suggests that BSHXF might be an effective option for alleviating low-back pain.
9
Eliminates back pain
Most Useful Review
10 people found this helpful
Major change after starting this. After breastfeeding for 12 months, I was in constant pain across my back, knees, and joints. Suggestions led me to this calcium supplement. Just three days in, nearly all my pain had vanished! Now pregnant again, my midwives say I’m the only woman in their practice with adequate vitamin D levels, thanks to this supplement. In summary, it’s the best and I urge everyone with bone issues to try it.

Chest Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.6
7.5
Improved hip pain
Most Useful Review
1 people found this helpful
Recommended by my doctor, I've noticed an improvement in my hip and lower back pain. It's also easy on my digestion.

High Cholesterol details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.4
2
Lack of effectiveness
Most Useful Review
I purchased Jarrow Formulas, BoneUp with hopes of improving my bone health. Unfortunately, after a month, I noticed no significant changes in my condition. The packaging is commendable, and the capsules are easily swallowed, but I still felt no difference. Three capsules a day is quite demanding, particularly given the lack of visible effects, making it less practical for my lifestyle. Overall, I'm quite let down and think it's better to explore alternatives that might provide actual benefits.
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