NOW Supplements MK-7 Vitamin K-2 100 mcg

Our exploration focused on how vitamin K2 supplementation may aid postmenopausal women dealing with osteoporosis, particularly regarding bone mineral density (BMD) and the incidence of fractures over the long term. We meticulously reviewed nine randomized controlled trials with nearly 6,900 participants to gather insightful data on this topic.

The results were promising, revealing that vitamin K2 significantly enhanced lumbar and forearm BMD. Specifically, we observed notable increases in bone density measurements, alongside a reduction in undercarboxylated osteocalcin—a marker associated with bone health, and a significant rise in total osteocalcin.

Although there was an increase in the rate of adverse reactions in the vitamin K2 group, we found no serious side effects stemming from the supplementation. Overall, our study supports the conclusion that vitamin K2 is not only effective but also safe for treating osteoporosis in postmenopausal women. This could provide a welcome option for those looking to improve their bone health.

9.5

Reduces osteoporosis risk

Most Useful Review

Vitamin K2 (MK-7) is essential for treating osteoporosis by removing calcium from arteries and directing it to bones. I take it regularly with vitamin D3 to strengthen my bones. In high doses, it lowers cholesterol and prevents vascular calcification. The 100 mcg dosage is optimal, and the packaging is intact. It could be cheaper, though!

Chronic Fatigue Syndrome details

Improved Well-being and Analysis

I've purchased this again due to the minimal packaging. It's a great vitamin! I took one capsule daily alongside vitamin D3 and omega as prescribed by my doctor. My vitamin D levels improved significantly, and I've experienced enhanced wellbeing, increased energy, better sleep, and reduced fatigue. I will definitely purchase more. I hope this helps. Stay healthy

Back Pain details

Vitamin K2 boosts back pain recovery

Concurrent Treatment with Vitamin K2 and D3 on Spine Fusion in Patients with Osteoporosis-Associated Lumbar Degenerative Disorders.

Most Relevant Research

We explored how treating patients with osteoporosis with vitamin K2 and D3 could influence back pain and spine fusion rates following surgery. In this study, we included patients who underwent spinal surgery for lumbar degenerative disorders. Some received a combination of vitamin K2, D3, and calcium, while others were treated with only calcium and vitamin D3.

The results showed that those who took vitamin K2 along with their other treatments had improved fusion rates and experienced less back pain. Furthermore, clinical symptoms improved, and there was a marked promotion of bone health within six months after surgery. Notably, the administration of vitamin K2 also helped maintain bone mineral density.

Overall, this research suggests that incorporating vitamin K2 alongside traditional treatments could be beneficial for individuals dealing with back pain related to osteoporosis. It opens the door for more studies on how we might better treat and manage spinal conditions in these patients.

9.5

Improved back pain

Most Useful Review

At last, Bone Density Increasing! I've suffered from severe osteopenia since my 30s, and despite a strict vegan diet and supplements, my bone density saw little change. After researching vitamin MK-7, I began taking it 15 months ago, leading to a 25% improvement in bone density. Unexpectedly, my chronic back pain has also lessened. I highly recommend MK-7 to anyone concerned with osteopenia or osteoporosis.

Vitamin K2 Inhibits Hepatocellular Carcinoma Cell Proliferation by Binding to 17β-Hydroxysteroid Dehydrogenase 4.

Most Relevant Research

We investigated how vitamin K2 (VK2) influences the growth of cancer cells, particularly focusing on hepatocellular carcinoma (HCC). Our study centered on the interaction between VK2 and a protein known as HSD17B4, which is known to promote cancer cell proliferation. Previous research had shown that VK2 can bind to this protein, but we aimed to uncover the specific mechanisms behind its potential anti-cancer effects.

Through our experiments, we observed that VK2 can inhibit the growth of HCC cells by binding directly to HSD17B4. Interestingly, VK2 did not alter the expression levels of HSD17B4, which suggests that its impact on cell growth is due to other mechanisms. Specifically, we found that VK2 impedes the activation of important signaling pathways, including AKT and MEK/ERK, which play a critical role in cancer cell proliferation. As a result, this inhibition leads to decreased activity of another protein, STAT3, associated with cancer growth.

Moreover, VK2 demonstrated the ability to suppress the growth of transplanted tumors that were influenced by HSD17B4. These findings not only shed light on VK2's mechanism of action, but they also offer promising insights into its potential role in preventing or treating HCC in future applications.

8.8

Antitumour properties

Most Useful Review

Vitamin K2 is vital for calcium absorption and blood clotting. It redirects calcium from the blood to bone tissue, which is crucial for bone and dental health. Notably, in 2006, its antitumour properties were discovered, showing benefits against certain cancers, including lung, pancreatic, bladder, and rectal. Ongoing studies continue to explore its potential.

Chest Pain details

Chest restriction relieved

Most Useful Review

Vitamin K, MK-7 works wonders for me. I have been taking it for five months to ensure calcium is properly deposited in my bones rather than my arteries. Recently, I noticed I can breathe deeply without feeling chest pain. The tightness I experienced during deep breathing exercises has diminished significantly. I'm now inspired to continue a heart health regime, including a smaller dose of Lysine and a high dose of Ascorbic Acid.

Common Cold details

Since taking vitamin D and K, I’ve avoided the common cold despite many around me falling ill. I attribute this to my supplement regimen and will continue taking them.

Heart Disease details

Reduces heart disease risk

Most Useful Review

I recommend a daily dose of 180 mcg of vitamin K2 (MK-7) for postmenopausal women and older men. It helps in calcium absorption, reduces coronary artery calcification, and overall mortality linked to heart disease. Statin users should consider K2 supplements, as statins lower vitamin K levels.

Kidney Stones details

This is the best form. I had been on steroids for seven consecutive bouts of bronchitis, which made my bones brittle. I ended up breaking a rib and puncturing a lung. My chiropractor recommended taking vitamin K2, saying it could remove calcium from arteries and kidney stones, directing it back to my bones and teeth. Since I started this, I have had no kidney stones and have seen noticeable improvements in kidney pain!

Arteriosclerosis details

SCIENTIFIC SCORE

Possibly Effective

Based on 15 Researches

Vitamin K2 may aid arteriosclerosis

Comparative effects of vitamin K2 and vitamin E on experimental arteriosclerosis.

Most Relevant Research

We explored the effects of vitamin K2 on arteriosclerosis by examining its impact on calcium and phosphorus levels in the aorta and the elastin fraction in male rats. This study was designed to assess how vitamin K2 (at doses of 100 mg/kg and 50 mg/kg) compares to vitamin E (at 40 mg/kg) in preventing the changes induced by a vitamin D2 and atherogenic diet that led to arteriosclerosis.

Our findings were promising. Both vitamin K2 and vitamin E appeared to inhibit increases in calcium and phosphorus levels in the aorta among the rats with arteriosclerosis. Specifically, the higher dose of vitamin K2 not only prevented these increases but also suppressed their deposition in the aorta. However, we observed that vitamin K3 and geranylgeraniol did not show similar benefits or radical scavenging activity.

Furthermore, both vitamin K2 and vitamin E demonstrated an ability to scavenge lipid radicals in vitro, indicating a potential mechanism for their protective effects. Overall, our study suggests that vitamin K2 may be an effective ally in managing arterial health by combating arteriosclerosis through these radical scavenging properties.

9.5

Reversing arteriosclerosis

Most Useful Review

Research using 360mcg a day to decalcify arteries has been beneficial for me. I’ve consistently returned to this product after learning about its role in decalcifying arterial plaque. Taking three and a half of these small, easy-to-swallow capsules daily is worthwhile, as there are few options that can reverse arteriosclerosis and vascular changes in the blood vessels. It truly feels like gaining another chance at life. Additionally, a shallow cavity I had vanished when I visited the dentist after using this product daily for several months. I’ve also noticed I have no tartar on my teeth since starting this routine.

Autoimmune Disorder details

An essential vitamin for an active life! This is my salvation! After taking K-2 for a week on my doctor's advice, I felt revitalised; my fatigue vanished by the end of long workdays. I will definitely order it regularly, especially for those engaged in physical exertion or living an active lifestyle.

Pneumonia details

After suffering pneumonia, my doctor recommended Omega-3 and vitamin D-3, emphasising the need for D-3 with K-2 MK-7. Vitamin K-2 MK-7 aids calcium absorption and metabolism with vitamin D. I take K-2 and D-3 (5000 IU) in the evening with fatty foods. K-2 MK-7 helps maintain bone health and reduces fragility in later years, directing calcium into bones rather than arteries. I highly recommend it.

Vertigo details

Helps vertigo control

Most Useful Review

I use this for my vertigo, alongside Vitamin D3.

Diabetes details

SCIENTIFIC SCORE

Questionable

Based on 15 Researches

Vitamin K2 aids bone healing

Effects of vitamin K2 administration on guided bone regeneration in diabetic rats.

Most Relevant Research

We studied how vitamin K2 influences bone regeneration in diabetic rats, especially focusing on its effects on healing critical-size defects in the skull. In our experiment, we included both non-diabetic and diabetic rats to see how this vitamin fares in conditions known to hinder healing.

With a diverse set of control and experimental groups, we treated some rats with vitamin K2 while others received a saline solution. After four weeks, we assessed bone healing through various tests, including looking at new bone formation and specific proteins linked to bone health.

The results were promising! We found that vitamin K2 significantly enhanced bone healing, especially when combined with a bone graft. New bone formation was notably higher in the groups treated with vitamin K2 compared to those that weren’t. Moreover, levels of osteocalcin and osteopontin—two key markers for bone health—were also elevated in these groups.

Overall, our findings suggest that vitamin K2 could be a beneficial addition to treatments aimed at improving bone regeneration in diabetic patients. This avenue offers interesting possibilities for enhancing recovery strategies in individuals with similar conditions.

8.8

Lowered cholesterol

Most Useful Review

I have struggled with high cholesterol for years, and despite a healthy lifestyle, my condition worsened. After starting statins, my issues escalated, including muscle pain and elevated A1C levels. Following my sibling's heart attack, I researched and began K-2 supplements. Within four months, my cholesterol returned to normal, allowing me to stop taking statins. I aim to normalise my A1C now. I feel everything in our bodies is interconnected, and I need to care for my blood sugar.

Flu details

Works great! This is a fantastic source of the most absorbable form of K2 (MK-7) and reasonably priced too. I have ordered this several times for my grandmother, and this has been her healthiest "cold and flu" season yet (she is also taking D3 5,000 IU and glutathione with this K2 MK-7). For the past six years, she has had at least one ER visit a winter for respiratory illness. However, this season, she has avoided the ER, except for an injury from launching a boat. K2 MK-7 with D3 is essential, as it prevents D3 from causing calcium deposits in the heart. I would and have purchased this again for her and myself!

Cold Sores details

I've been purchasing MK-7 repeatedly as it's so effective. While I could get it from natto, consuming it daily is difficult, so I replenish when I run out. Alongside other vitamins, MK-7 has notably reduced my cold sores and the severe period pain I experienced.

Heart Attack details

SCIENTIFIC SCORE

Moderately Effective

Based on 2 Researches

Menaquinone-4 aids heart recovery

Potential Cardioprotective Role of Menaquinone-4 Against Cardiac Ischemia-reperfusion Injury.

Most Relevant Research

We examined how Menaquinone-4, a form of vitamin K2, could help protect the heart during a critical event known as ischemia-reperfusion (I/R) injury, which often occurs after heart attacks. In our study, we used thirty-two rats, dividing them into three groups: a control group that experienced I/R without treatment, a group that received MK-4 before the injury, and another group that got MK-4 at the beginning of the recovery phase.

By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.

Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.

9.5

Plaque reduction

Most Useful Review

Following a heart attack in February 2018, I adopted a plant-based diet and took this product alongside vitamin D3. Remarkably, a recent CT scan revealed that the plaque in my left artery reduced significantly from 95% to moderate, while the other arteries were clear of plaque. I'm grateful for the progress made.