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Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin D2 (as Ergocalciferol)
25 mcg (1,000 IU)
125%
The product is found useful for the following medical conditions
Leg Cramps
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 3 Reviews
9.5
9.5
Excellent results
Most Useful Review
The quality is exceptional; I had a deficiency which caused my bones in my arms and legs to ache. I noticed the results immediately and found the size comfortable.
Menopause
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
6
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
4
Vitamin D2 shows limited impact
Effectiveness of vitamin D2 supplementation on high-sensitivity C-reactive protein and other metabolic indices in menopausal Thai women: a randomized-controlled trial.
Most Relevant Research
We conducted a double-blind, randomized, placebo-controlled trial to investigate the impact of vitamin D2 supplementation on high-sensitivity C-reactive protein (hsCRP) levels and other metabolic measures among menopausal Thai women.
Eighty postmenopausal women participated in the study, where they were split into two groups: one receiving vitamin D2 at a dose of 40,000 IU per week and the other receiving a placebo for a duration of 12 weeks. The primary focus was on hsCRP levels, a marker linked to inflammation, while secondary outcomes included various cardio-metabolic profiles and the risk of developing cardiovascular disease.
Our findings showed that although the vitamin D2 group experienced a notable reduction in hsCRP levels compared to the placebo group, the difference wasn't statistically significant by the end of the study. Other measured cardiovascular and metabolic outcomes also didn't show significant differences between the two groups.
Thus, while vitamin D2 appears to reduce inflammation markers in menopausal women, the overall benefits in hsCRP levels didn't reach statistical significance when compared to the placebo. This indicates a need for further research before making definitive conclusions about the benefits of vitamin D2 in this context.
Eighty postmenopausal women participated in the study, where they were split into two groups: one receiving vitamin D2 at a dose of 40,000 IU per week and the other receiving a placebo for a duration of 12 weeks. The primary focus was on hsCRP levels, a marker linked to inflammation, while secondary outcomes included various cardio-metabolic profiles and the risk of developing cardiovascular disease.
Our findings showed that although the vitamin D2 group experienced a notable reduction in hsCRP levels compared to the placebo group, the difference wasn't statistically significant by the end of the study. Other measured cardiovascular and metabolic outcomes also didn't show significant differences between the two groups.
Thus, while vitamin D2 appears to reduce inflammation markers in menopausal women, the overall benefits in hsCRP levels didn't reach statistical significance when compared to the placebo. This indicates a need for further research before making definitive conclusions about the benefits of vitamin D2 in this context.
9.5
Effective for menopause
Most Useful Review
It truly worked for my mother's menopause. She had uterine fibroid surgery and found it challenging to use female hormones, so I sought alternative options for her menopause management and it proved beneficial.
Headache
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Researches
9
USERS' SCORE
Excellent
Based on 2 Reviews
9.3
9
Vitamin D's Impact on Headaches
Resolution of hypersomnia following identification and treatment of vitamin d deficiency.
Most Relevant Research
We explored how vitamin D treatment can influence headache severity in patients. In this case study, a 28-year-old woman experienced excessive daytime sleepiness without clear causes such as sleep disorders. Her symptoms included significant fatigue, chronic pain in her thighs and lower back, and daily headaches.
After identifying that she had low levels of vitamin D, we initiated supplementation, which quickly led to notable improvements. Within just a couple of weeks, her headaches improved significantly alongside her daytime tiredness. By the end of the treatment, both her headaches and other chronic pain issues had resolved or greatly diminished.
However, while the study indicates an association between vitamin D treatment and headache relief, it does not specifically isolate the effect of vitamin D2 solely on headaches. Therefore, while we saw encouraging improvements, we must note that further research is needed to establish a more direct link between vitamin D treatment and headache relief specifically.
After identifying that she had low levels of vitamin D, we initiated supplementation, which quickly led to notable improvements. Within just a couple of weeks, her headaches improved significantly alongside her daytime tiredness. By the end of the treatment, both her headaches and other chronic pain issues had resolved or greatly diminished.
However, while the study indicates an association between vitamin D treatment and headache relief, it does not specifically isolate the effect of vitamin D2 solely on headaches. Therefore, while we saw encouraging improvements, we must note that further research is needed to establish a more direct link between vitamin D treatment and headache relief specifically.
9.5
No headaches experienced
Most Useful Review
Perfect! I have struggled to take any form of Vitamin D without suffering from massive headaches for nearly 20 years. Finally, I read about someone similar who switched to D2, and it worked. I'm eagerly awaiting my blood work to show an increase in Vitamin D for the first time in years, but for now, I am taking six capsules a day without any headaches!
Autoimmune Disorder
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 2 Reviews
9.2
9.5
Prevention success
Most Useful Review
Excellent D3! I take this dosage during summer, and for the rest of the year, I have 2000 IU from the same manufacturer. Over two years, my family hasn't caught any colds, and we were asymptomatic even during the pandemic. This supplement has been essential in managing our immune health, particularly in relation to autoimmune disorders.
Liver Disease
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 2 Reviews
9.2
9.5
Essential for immunity
Most Useful Review
This is a crucial vitamin for our body. I bought it for my brother as it was prescribed by his doctor. I intended to purchase it again, but it’s now unavailable. This vitamin is vital for immunity, especially if one suffers from liver disease.
Common Cold
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 8 Reviews
8.9
10
Family immunity
Most Useful Review
I order this dosage for summer, but during the rest of the year, I take 2000 IU from the same brand. The significant result is that my family hasn't caught a common cold or any illness for 2 years, even through challenges like the recent pandemic.
Back Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 2 Reviews
8.8
9.5
No more back pain
Most Useful Review
Another great Now product. The capsules are small and straightforward to swallow, and they seem effective. I usually experience leg pain when my vitamin D is low, but since starting this, I haven't had any leg pain or back pain.
Eczema
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
Eczema improvement
Most Useful Review
I have noticed a difference within a few months of taking this supplement; my eczema has improved, with reduced itching and inflammation.
Hashimoto
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
Effective Vitamin D
Most Useful Review
Simple Vitamin D. The one I take for Hashimoto’s is very good; otherwise, I wouldn't be able to purchase Vitamin D.
Osteoporosis
SCIENTIFIC SCORE
Most Likely Effective
Based on 6 Researches
8.3
USERS' SCORE
Very Good
Based on 7 Reviews
8.8
9
Doxercalciferol improves bone health
Doxercalciferol Alleviates Bone Deteriorations and Cartilage Degeneration in Aging Mice.
Most Relevant Research
We sought to understand how doxercalciferol, a form of vitamin D2, affects bone health in aging mice, particularly in relation to osteoporosis. Through a series of experiments, we investigated its potential benefits in preventing bone loss, a common issue as animals age.
Our findings revealed that aging mice exhibited increased urine calcium excretion, decreased bone calcium content, and a reduction in biomechanical strength. However, upon administering doxercalciferol, we observed significant effects; especially, it lowered serum parathyroid hormone (PTH) levels which are commonly elevated in aging.
Additionally, our analysis through specific staining techniques confirmed that doxercalciferol helped protect against bone loss and supported cartilage regeneration. We also noted that the treatment enhanced the activity of bone-building cells while inhibiting the activity of cells that break down bone.
Overall, these results suggest that doxercalciferol could be an effective treatment for aging-related osteoporosis by enhancing bone health and improving overall quality of life.
Our findings revealed that aging mice exhibited increased urine calcium excretion, decreased bone calcium content, and a reduction in biomechanical strength. However, upon administering doxercalciferol, we observed significant effects; especially, it lowered serum parathyroid hormone (PTH) levels which are commonly elevated in aging.
Additionally, our analysis through specific staining techniques confirmed that doxercalciferol helped protect against bone loss and supported cartilage regeneration. We also noted that the treatment enhanced the activity of bone-building cells while inhibiting the activity of cells that break down bone.
Overall, these results suggest that doxercalciferol could be an effective treatment for aging-related osteoporosis by enhancing bone health and improving overall quality of life.
9.5
Helps manage osteoporosis
Most Useful Review
Excellent! This product is crucial for me due to osteoporosis. Following my doctor's recommendation, it has been beneficial.
Allergies
SCIENTIFIC SCORE
Most Likely Effective
Based on 3 Researches
7.7
USERS' SCORE
Very Good
Based on 3 Reviews
8.6
8
Vitamin D2 aids allergy management
Vitamin d supplements improve urticaria symptoms and quality of life in chronic spontaneous urticaria patients: a prospective case-control study.
Most Relevant Research
We explored the role of vitamin D2 in managing symptoms of chronic spontaneous urticaria (CSU), a persistent skin condition that can be quite bothersome. In our study, we included 60 patients with CSU and 40 healthy individuals for comparison.
Participants underwent vitamin D testing, and those with low levels were given a high-dose vitamin D2 supplement along with antihistamines for six weeks. Our findings revealed that a significant number of CSU patients had low vitamin D levels, which were notably lower than those in the control group.
After the six-week treatment period, we observed considerable improvements in both allergy symptoms and overall quality of life among those taking vitamin D2. Specifically, many reported feeling better and experiencing fewer urticaria symptoms. This suggests that vitamin D2 could play a beneficial role in managing allergies, especially in those with existing deficiencies.
However, it's important to note that vitamin D2 was administered alongside antihistamines, so we can't pinpoint its effect without considering the medications’ impacts. Overall, our study offers promising insights into how vitamin D2 might support individuals dealing with allergic conditions like CSU.
Participants underwent vitamin D testing, and those with low levels were given a high-dose vitamin D2 supplement along with antihistamines for six weeks. Our findings revealed that a significant number of CSU patients had low vitamin D levels, which were notably lower than those in the control group.
After the six-week treatment period, we observed considerable improvements in both allergy symptoms and overall quality of life among those taking vitamin D2. Specifically, many reported feeling better and experiencing fewer urticaria symptoms. This suggests that vitamin D2 could play a beneficial role in managing allergies, especially in those with existing deficiencies.
However, it's important to note that vitamin D2 was administered alongside antihistamines, so we can't pinpoint its effect without considering the medications’ impacts. Overall, our study offers promising insights into how vitamin D2 might support individuals dealing with allergic conditions like CSU.
9.5
Boosted immunity
Most Useful Review
I ordered this supplement for my son, who has a D deficiency and allergies to D3, along with low immunity. It has excellent ingredients and is a high-quality product.
Bone Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 15 Reviews
8.5
9.5
Effective for pain
Most Useful Review
Vitamin D is crucial for vegans, especially if they don't consume vitamin D-rich foods like mushrooms. I developed bone pain due to a deficiency from lack of sunlight. However, after taking this supplement, my pain disappeared within two weeks. It’s affordable and vegan-friendly, making it easier to ensure sufficient intake for bone health.
Knee Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 2 Reviews
8.5
9.5
No leg pain
Most Useful Review
Another great product from Now. The capsules are small and easy to swallow. They appear to be effective as I’ve not experienced leg pain, which I usually get when I don’t have enough Vitamin D, since taking them.
Depression
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 10 Reviews
8.4
9.5
Essential winter item
Most Useful Review
In a country with minimal sunlight, vitamin D is crucial for me in winter. Since starting it in November, I haven't faced any physical or mental issues, suggesting it's effective.
Acne
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
7.5
7.5
No acne issues
Most Useful Review
I previously took another brand of Vitamin D3 that helped me lose weight but caused acne. This product is great as it doesn't trigger acne and has the right dosage. After taking it, my chin may get slightly red briefly, but there are no side effects, so I take it daily.
Cancer
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
7.5
7.5
Enhances immunity
Most Useful Review
The quality is excellent, the effect is effective, and the price is reasonable. Vitamin D, the sun vitamin, compensates for the lack of sunlight exposure and boosts bone strength when used with magnesium regularly. It enhances immunity and may help protect against cancer if taken consistently. To maximise absorption, ensure you get some sunlight; just half an hour can yield remarkable results.
Cold Sores
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
7
7
Effective cold prevention
Most Useful Review
Generally, it is effective in preventing colds.
Chronic Fatigue Syndrome
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 6 Reviews
6.7
9.5
Enhanced energy
Most Useful Review
An inexpensive vitamin D that helps maintain blood levels, suitable for children. I noticed having more energy and less fatigue, and waking up was easier. It significantly bolstered my immunity against chronic fatigue syndrome.
