Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
1 g (1,000 mg)
1111%
Rose Hips Powder (Rosa canina) (fruit)
25 mg
†
The product is found useful for the following medical conditions
Eczema details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 2 Reviews
8.7
7
We assessed the impact of vitamin C and other nutrients on workers suffering from skin eczema due to their job in perlite production. The study involved a group of 165 workers with eczema and a control group of 152 workers without any skin issues, allowing us to compare the effects more accurately.
Participants were included on a specialized diet featuring kissel, rich in pectin, vitamin A, vitamin E, and zinc. Notably, we saw significant improvements in several important indicators. For instance, the levels of ascorbic acid in the blood increased by 30%, while tocopherol levels rose by 36.3%. Additionally, we observed enhanced levels of carotenoids, phosphorus, and calcium.
There was a notable reduction in malondialdehyde (MDA), which can indicate oxidative stress, alongside a slight increase in catalase activity, suggesting overall improvements in the body’s ability to fight inflammation. While these findings suggest a positive trend towards reducing symptoms such as itching and redness, it’s essential to note that the study didn't isolate the effects of vitamin C alone, leaving us without a clear conclusion on its specific role in relieving eczema.
Consequently, while the combination of nutritional factors, including vitamin C, shows promise in enhancing skin health and fighting occupational eczema, we need further research to fully understand how much of this benefit can be attributed to vitamin C by itself.
Participants were included on a specialized diet featuring kissel, rich in pectin, vitamin A, vitamin E, and zinc. Notably, we saw significant improvements in several important indicators. For instance, the levels of ascorbic acid in the blood increased by 30%, while tocopherol levels rose by 36.3%. Additionally, we observed enhanced levels of carotenoids, phosphorus, and calcium.
There was a notable reduction in malondialdehyde (MDA), which can indicate oxidative stress, alongside a slight increase in catalase activity, suggesting overall improvements in the body’s ability to fight inflammation. While these findings suggest a positive trend towards reducing symptoms such as itching and redness, it’s essential to note that the study didn't isolate the effects of vitamin C alone, leaving us without a clear conclusion on its specific role in relieving eczema.
Consequently, while the combination of nutritional factors, including vitamin C, shows promise in enhancing skin health and fighting occupational eczema, we need further research to fully understand how much of this benefit can be attributed to vitamin C by itself.
10
Quick eczema relief
Most Useful Review
It's healed! The eczema on my ankle disappeared within two days!
Updated: Apr 2025
Bronchitis details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Vitamin C aids bronchitis resistance
We explored how supplementing the diet of broiler chicks with different levels of vitamin C, also known as ascorbic acid, impacts their resistance to infectious bronchitis virus. The goal was to determine whether this supplement could help improve their health by measuring the severity of tracheal lesions and the presence of airsacculitis after exposure to the virus.
Our findings indicated that the effectiveness of vitamin C was dose-dependent. We observed that adding between 300 to 330 parts per million (ppm) of ascorbic acid to their feed yielded the best protective results. Interestingly, when we looked at higher concentrations—beyond 600 ppm—the benefits seemed to diminish. This suggests that while vitamin C can be beneficial, there's a suitable range for its effectiveness.
Overall, this study highlights the potential of vitamin C as a useful dietary addition for enhancing the health of broilers facing bronchitis. Yet, it's clear that more isn't always better when it comes to dosage, and finding that sweet spot is crucial for maximizing its effectiveness.
Our findings indicated that the effectiveness of vitamin C was dose-dependent. We observed that adding between 300 to 330 parts per million (ppm) of ascorbic acid to their feed yielded the best protective results. Interestingly, when we looked at higher concentrations—beyond 600 ppm—the benefits seemed to diminish. This suggests that while vitamin C can be beneficial, there's a suitable range for its effectiveness.
Overall, this study highlights the potential of vitamin C as a useful dietary addition for enhancing the health of broilers facing bronchitis. Yet, it's clear that more isn't always better when it comes to dosage, and finding that sweet spot is crucial for maximizing its effectiveness.
10
Significant improvement
Most Useful Review
2 people found this helpful
Recommend. I had been ill for three weeks with prolonged bronchitis. I tried antibiotics, but they had no effect. After starting vitamin C on the fifth day, I noticed an immediate improvement and didn't even realise I was getting better. The impact on my complexion was remarkable; my skin is clear and radiant. I'm genuinely pleased with the results. Additionally, I've been taking it for three months now, and my usual vasomotor rhinitis and persistent nasal congestion have vanished. My skin remains beautiful.
Updated: Apr 2025
Gout details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
We investigated the potential relationship between dietary vitamin C intake and gout among American adults using data from the National Health and Nutrition Examination Survey conducted between 2013 and 2018. This study included participants over the age of 20 and looked at various factors, including the incidence of gout and levels of vitamin C intake.
Our findings revealed that 5% of the 12,589 participants reported experiencing gout. Interestingly, those consuming higher amounts of dietary vitamin C showed a lower likelihood of developing gout. Specifically, individuals in the highest intake group had an odds ratio of 0.77 for having gout, suggesting an inverse relationship between vitamin C intake and gout occurrence.
We noted that this relationship exhibited an L-shaped pattern, indicating that increased vitamin C consumption may be linked to reduced gout risk, particularly among different sex groups. However, when we examined vitamin C supplements, no significant association with gout was observed. Overall, our research highlights the potential benefits of dietary vitamin C in preventing gout, while underscoring the need for more focused studies in this area.
Our findings revealed that 5% of the 12,589 participants reported experiencing gout. Interestingly, those consuming higher amounts of dietary vitamin C showed a lower likelihood of developing gout. Specifically, individuals in the highest intake group had an odds ratio of 0.77 for having gout, suggesting an inverse relationship between vitamin C intake and gout occurrence.
We noted that this relationship exhibited an L-shaped pattern, indicating that increased vitamin C consumption may be linked to reduced gout risk, particularly among different sex groups. However, when we examined vitamin C supplements, no significant association with gout was observed. Overall, our research highlights the potential benefits of dietary vitamin C in preventing gout, while underscoring the need for more focused studies in this area.
9
Boosts immunity
Most Useful Review
I am pleased with it. I take it to manage my gout and to enhance my immunity.
Updated: Apr 2025
Reflux details
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.
This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
9
No heartburn issues
Most Useful Review
86 people found this helpful
NOW brand doesn’t trigger heartburn or acid reflux in my wife. We’ve tried other vitamin C brands that caused her awful heartburn. We've been using NOW vitamin C for a while now (on our second bottle) and she hasn’t experienced any heartburn or acid reflux issues. The pills are not particularly small but are manageable. I can’t recall the last time I was sick, and I genuinely believe that taking vitamin C contributes to that. I typically take two tablets a day (2000 mg total), one with breakfast and another with dinner, and I increase to four when in crowded situations.
Updated: Mar 2026
Rosacea details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.6
9
We explored the effectiveness of Rutin Forte, a treatment that includes long-acting vitamin C along with zinc and selenium, in managing rosacea, particularly in its erythematous stage. Our study included 30 patients—20 women and 10 men, aged 25 to 50—who were divided into two groups. One group received standard treatments like antibiotics and topical therapies, while the other group received the same treatments along with Rutin Forte for 2 to 3 months.
Over a 12-month observation period, we observed significant improvements in the group that received Rutin Forte. This group showed a notable reduction in erythema, the redness associated with rosacea, and intriguingly, there were no relapses of the condition. Conversely, the standard treatment group experienced recurrences of rosacea by the third month of follow-up, and their reduction in erythema was less pronounced.
This indicates that Rutin Forte, likely due to the vitamin C it contains, might play a beneficial role in treating and preventing rosacea symptoms, particularly in stubborn cases. Overall, our findings suggest that incorporating vitamin C into rosacea treatment can be quite effective.
Over a 12-month observation period, we observed significant improvements in the group that received Rutin Forte. This group showed a notable reduction in erythema, the redness associated with rosacea, and intriguingly, there were no relapses of the condition. Conversely, the standard treatment group experienced recurrences of rosacea by the third month of follow-up, and their reduction in erythema was less pronounced.
This indicates that Rutin Forte, likely due to the vitamin C it contains, might play a beneficial role in treating and preventing rosacea symptoms, particularly in stubborn cases. Overall, our findings suggest that incorporating vitamin C into rosacea treatment can be quite effective.
10
Supports blood vessels
Most Useful Review
PERFECT DUET and FIX with RUTIN for rosacea symptoms! The anti-inflammatory bioflavonoids in Vitamin C help support weakened blood vessels. Researchers suggest that the redness of rosacea may stem from overly dilating blood vessels, and thus strengthening them with Vitamin C can alleviate inflammation. Vitamin C is effective across all skin types and is gentle on sensitive skin, making it a great ally for those with rosacea. Using it alongside Rutin for 45 days has noticeably reduced my rosacea and strengthened my blood vessels. At 63 years old, I feel good with this product!
Updated: Apr 2025
Sinusitis details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 5 Reviews
8.6
8
We explored the effects of L-ascorbate, commonly known as Vitamin C, on chloride transport in sinonasal epithelial tissues. This research is particularly significant as it addresses the common condition of chronic rhinosinusitis (CRS) and its potential link to the function of the cystic fibrosis transmembrane conductance regulator (CFTR) — a key chloride ion channel.
During our investigation, we utilized freshly excised sinonasal tissues from both normal individuals and patients suffering from CRS. The tissues were carefully prepared and tested to understand how L-ascorbate influenced chloride secretion. Our findings revealed that the application of L-ascorbate notably enhanced chloride secretion in these tissues.
This is important because optimal chloride transport is essential for maintaining healthy mucosal surfaces and effective mucociliary clearance. Therefore, since decreased chloride secretion could lead to the worsening of sinus conditions, L-ascorbate presents a promising avenue for therapeutic intervention in improving mucociliary clearance for those affected by chronic sinus issues.
During our investigation, we utilized freshly excised sinonasal tissues from both normal individuals and patients suffering from CRS. The tissues were carefully prepared and tested to understand how L-ascorbate influenced chloride secretion. Our findings revealed that the application of L-ascorbate notably enhanced chloride secretion in these tissues.
This is important because optimal chloride transport is essential for maintaining healthy mucosal surfaces and effective mucociliary clearance. Therefore, since decreased chloride secretion could lead to the worsening of sinus conditions, L-ascorbate presents a promising avenue for therapeutic intervention in improving mucociliary clearance for those affected by chronic sinus issues.
9
Improved immunity
Most Useful Review
1 people found this helpful
I have been taking this since the day after my birth. It is truly effective in boosting my immunity, as I have not been sick for a year now. No cough, colds, Sinusitis, rhinitis, or tonsillitis, which I used to get frequently. Moreover, it has even made my skin fairer. 😚😚
Updated: Apr 2026
Acne Rosacea details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.5
9
Minimised redness
Most Useful Review
I commenced taking Vitamin C around a month and a half ago and I am achieving remarkable results! My skin has become cleaner, brighter, and fairer. It has seemingly reduced my acne rosacea redness, and impressively, it has fortified my gums—stopping the recession! I’ve been investing significantly in dental treatments every six months! This vitamin is one of the best supplements I've ever used!
Updated: Apr 2025
Anxiety details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 4 Reviews
8.5
8
Vitamin C alleviates anxiety in autism
We set out to explore how vitamin C influences anxiety-like behaviors in a model of autism caused by valproic acid (VPA). In our study, we used fourteen female rats that underwent specific treatments to induce autism in their offspring. After a period of observation, we treated male pups with daily injections of vitamin C for four weeks. Then, we assessed their behavior to see if there were any changes in anxiety levels.
Our findings suggested that vitamin C significantly reduced anxiety-like behaviors in these rats. This outcome is particularly promising considering that autism often brings associated anxiety. By measuring various brain oxidative stress markers, we also noted improvements in mental functioning and motor skills after vitamin C treatment. Overall, our work underscores the potential benefits of vitamin C as a supportive treatment for anxiety-related issues in autism, indicating a pathway for future research and therapeutic strategies.
Our findings suggested that vitamin C significantly reduced anxiety-like behaviors in these rats. This outcome is particularly promising considering that autism often brings associated anxiety. By measuring various brain oxidative stress markers, we also noted improvements in mental functioning and motor skills after vitamin C treatment. Overall, our work underscores the potential benefits of vitamin C as a supportive treatment for anxiety-related issues in autism, indicating a pathway for future research and therapeutic strategies.
9
Enhances well-being
Most Useful Review
An excellent supplement that improves well-being. It alleviates anxiety and promotes cheerfulness and a good mood.
Updated: Mar 2026
Bacterial Infection details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 13 Reviews
8.5
9
Boosts health effectively
Most Useful Review
5 people found this helpful
My family and I take 1000 mg of vitamin C at the first sign of a cold or other infection. It's also beneficial for skin, bones, and joints. At home, I prefer powdered sodium ascorbate, taking 2-4 g daily during viral infections. It helps me avoid illness. The packaging is convenient, with a jar of 250 tablets. The quality is excellent with natural ingredients! One tablet's dosage is ample for treating acute respiratory infections. Highly recommend! Wishing good health to everyone!
Updated: Apr 2025
Bloating details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 7 Reviews
8.5
7
We aimed to explore how different measures of vitamin C might influence premenstrual symptoms, particularly bloating. In this study, we analyzed data from 555 women aged 20 to 29 years who reported on various symptoms associated with their menstrual cycles. We looked at their dietary intake of vitamin C, measured serum ascorbic acid levels, and assessed genetic factors through DNA testing.
Our findings suggest that higher vitamin C status is linked to increased appetite changes and symptoms like bloating and swelling during the premenstrual phase. While we observed associations between vitamin C levels and these symptoms, it's important to note that our study didn't isolate the effect of vitamin C from other dietary influences. Therefore, while there's a connection between vitamin C and bloating, we cannot conclusively say that vitamin C alone is definitive in relief.
Overall, this research opens the door to understanding how nutrition, particularly vitamin C intake, may shape our experiences with premenstrual symptoms. However, it also highlights the complexity of diet's role in our health.
Our findings suggest that higher vitamin C status is linked to increased appetite changes and symptoms like bloating and swelling during the premenstrual phase. While we observed associations between vitamin C levels and these symptoms, it's important to note that our study didn't isolate the effect of vitamin C from other dietary influences. Therefore, while there's a connection between vitamin C and bloating, we cannot conclusively say that vitamin C alone is definitive in relief.
Overall, this research opens the door to understanding how nutrition, particularly vitamin C intake, may shape our experiences with premenstrual symptoms. However, it also highlights the complexity of diet's role in our health.
9
No more bloating
Most Useful Review
The grains are large, but once you adapt, they're fine. Since I switched to the time-release vitamin C, my stomach is no longer bloated, even after taking vitamin C. The inclusion of rosehip is also a significant advantage, as it is efficiently utilised in the body.
Updated: Apr 2025
Bruise details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.2
USERS' SCORE
Good
Based on 7 Reviews
8.5
8
We explored how vitamin C can impact bruising, particularly in individuals experiencing a deficiency. The research highlighted a case involving an elderly woman who faced challenges such as weakness, easy bruising, and fatigue due to a lack of this vital nutrient.
After beginning treatment with vitamin C supplements, we observed significant improvements in her symptoms, emphasizing the importance of this vitamin in healthier skin and tissue repair. It showcased that scurvy, a condition rooted in vitamin C deficiency, can still occur today, especially in certain at-risk populations.
This case reminds us that while scurvy might seem like a relic of the past, it can still affect modern individuals. Skin issues like easy bruising can sometimes signal deeper dietary concerns that need addressing, especially in older adults.
After beginning treatment with vitamin C supplements, we observed significant improvements in her symptoms, emphasizing the importance of this vitamin in healthier skin and tissue repair. It showcased that scurvy, a condition rooted in vitamin C deficiency, can still occur today, especially in certain at-risk populations.
This case reminds us that while scurvy might seem like a relic of the past, it can still affect modern individuals. Skin issues like easy bruising can sometimes signal deeper dietary concerns that need addressing, especially in older adults.
9
Stopped bruising
Most Useful Review
Good quality and quantity; it's a very important antioxidant, and I have stopped bruising since I began taking it.
Updated: Apr 2026
Chronic Cough details
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Good
Based on 3 Reviews
8.5
7
Dietary vitamin C reduces smoking-related cough
A survey of 4,300 young Norwegian adults examined whether dietary vitamin C intake relates to respiratory symptoms like cough and wheeze. Researchers estimated vitamin C consumption through questions about orange juice, oranges, potatoes, carrots, and tomatoes over the past year.
Among current smokers, those consuming more dietary vitamin C (395+ mg/week versus under 209 mg/week) showed reduced odds of morning cough and chronic cough. The protective effect was even stronger for ex-smokers experiencing wheeze. These benefits held true even after excluding people taking vitamin C supplements, suggesting the effect comes from food sources themselves.
The findings suggest that vitamin C's antioxidant properties may help counteract oxidative stress caused by smoking, potentially easing respiratory symptoms in smokers specifically.
Among current smokers, those consuming more dietary vitamin C (395+ mg/week versus under 209 mg/week) showed reduced odds of morning cough and chronic cough. The protective effect was even stronger for ex-smokers experiencing wheeze. These benefits held true even after excluding people taking vitamin C supplements, suggesting the effect comes from food sources themselves.
The findings suggest that vitamin C's antioxidant properties may help counteract oxidative stress caused by smoking, potentially easing respiratory symptoms in smokers specifically.
9
Effective aid
Most Useful Review
10 people found this helpful
SHOCK DOSE from chronic fatigue. When my strength is at its limit, I take one pill. The effect is nearly the same as having a glass of freshly squeezed orange juice! It’s a staple in my first aid kit!
Updated: Apr 2026
Frozen Shoulder details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
In our controlled laboratory study, we aimed to investigate whether vitamin C could help prevent frozen shoulder, particularly the secondary type that often occurs after trauma or surgery. We created a shoulder contracture model using Sprague-Dawley rats, which involved immobilizing their right shoulder.
Our experimental group, consisting of eight rats, received vitamin C orally, while a control group of nine rats did not receive vitamin C. We primarily measured the thickness of the joint capsule at the shoulder using magnetic resonance imaging (MRI).
The results were promising, indicating that vitamin C may reduce the thickening of the joint capsule linked to secondary frozen shoulder. Although we also conducted histological examinations, we did not perform statistical analysis on those findings due to variability in our cutting techniques.
This preclinical study suggests that vitamin C could be a valuable, non-invasive way to prevent secondary frozen shoulder, particularly in situations involving surgery or immobilization. However, more research is needed to determine its effects on humans and establish proper dosage guidelines.
Our experimental group, consisting of eight rats, received vitamin C orally, while a control group of nine rats did not receive vitamin C. We primarily measured the thickness of the joint capsule at the shoulder using magnetic resonance imaging (MRI).
The results were promising, indicating that vitamin C may reduce the thickening of the joint capsule linked to secondary frozen shoulder. Although we also conducted histological examinations, we did not perform statistical analysis on those findings due to variability in our cutting techniques.
This preclinical study suggests that vitamin C could be a valuable, non-invasive way to prevent secondary frozen shoulder, particularly in situations involving surgery or immobilization. However, more research is needed to determine its effects on humans and establish proper dosage guidelines.
9
Strengthened immunity
Most Useful Review
This greatly supports my immunity. I have been taking it for six months, which has boosted my body's resistance to viruses and colds. If I feel chilly outdoors, I take one capsule in the evening, which means I avoid any runny nose or cough. I highly recommend this product, as it has worked well for me.
Updated: Mar 2026
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 10 Reviews
8.5
8
We aimed to understand how dietary vitamin C affects migraines by analyzing data from the National Health and Nutrition Examination Survey, conducted from 1999 to 2004. In this survey, we identified adults who reported experiencing severe headaches or migraines over the past three months.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.
We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.
Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
9
Effective for sinus headaches
Most Useful Review
21 people found this helpful
This has been a life-saver for my allergic rhinitis. After many years of struggle, I discovered Vitamin C as my remedy. While I typically prefer freshly squeezed juices, I take Vitamin C pills when I feel congested or have a severe sinus headache; within a day, the headache often dissipates. This vitamin has been especially helpful during our trip to Switzerland. My husband also benefits from taking Quercetin alongside it.
Updated: Apr 2026
Heart Attack details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 2 Reviews
8.5
7
Antioxidants tested for heart attacks
In a recent clinical trial, we examined how a combination of antioxidants, including vitamin C, affects heart attack recovery. This study involved healthy participants who received either a blend of antioxidants or a placebo through an intravenous infusion. We measured the levels of vitamin C and other components in the blood, looking for signs of oxidative stress and monitoring any adverse effects.
Our findings showed that the antioxidant combination significantly increased vitamin concentrations compared to the placebo group. Moreover, we observed that this therapy seemed safe, with only mild, non-serious side effects reported in a small number of participants.
While antioxidants like vitamin C have been linked to health benefits, this study focused primarily on their safety and levels in the blood during a heart-related procedure. Although promising, we cannot definitively say that this approach improves outcomes for heart attack patients just yet. More research will be needed to explore its effectiveness further.
Our findings showed that the antioxidant combination significantly increased vitamin concentrations compared to the placebo group. Moreover, we observed that this therapy seemed safe, with only mild, non-serious side effects reported in a small number of participants.
While antioxidants like vitamin C have been linked to health benefits, this study focused primarily on their safety and levels in the blood during a heart-related procedure. Although promising, we cannot definitively say that this approach improves outcomes for heart attack patients just yet. More research will be needed to explore its effectiveness further.
9
Heart health improvement
Most Useful Review
1 people found this helpful
Excellent! Highly recommended! I have taken high doses of vitamin C to improve my heart condition. It has noticeably enhanced my skin, hair, and overall health. Despite being around many people with Covid, I have avoided infection, which I attribute to taking substantial amounts of vitamin C and also vitamin D. It is crucial to supplement with vitamin C since our bodies do not produce it, and most of us are unknowingly deficient.
Updated: Apr 2025
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Good
Based on 2 Reviews
8.5
7
We aimed to understand the role of vitamin C in heart disease and its potential cardioprotective effects. Vitamin C is renowned for its antioxidant properties, which means it fights off harmful substances in our body, potentially reducing the risk of heart issues.
Our analysis revealed that vitamin C could play a meaningful role in supporting cardiovascular health. While the evidence is promising, it is important to be cautious, as clinical studies have shown mixed results regarding its effectiveness.
So, while vitamin C might contribute positively to heart health, more solid evidence is required to fully confirm these effects. Overall, we learned that while there are positive indicators, we should be careful about over-relying on vitamin C as a sole preventive measure for heart disease.
Our analysis revealed that vitamin C could play a meaningful role in supporting cardiovascular health. While the evidence is promising, it is important to be cautious, as clinical studies have shown mixed results regarding its effectiveness.
So, while vitamin C might contribute positively to heart health, more solid evidence is required to fully confirm these effects. Overall, we learned that while there are positive indicators, we should be careful about over-relying on vitamin C as a sole preventive measure for heart disease.
9
Improved heart condition
Most Useful Review
1 people found this helpful
Excellent! Highly recommended! I have been taking high doses of vitamin C for my heart disease, which has significantly improved my overall health. My skin and hair have benefited too. Despite being in contact with many Covid patients, I haven't contracted the virus, likely due to my vitamin C and D intake. Supplementing with vitamin C is crucial since our bodies cannot produce it, and many of us lack it without realising.
Updated: Apr 2025
Knee Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
We observed an intriguing case involving a 4.5-year-old boy who developed significant knee pain due to a rare nutritional deficiency, scurvy. This condition stemmed from his exclusive intake of meat over the past two years, resulting in skeletal issues and inflammation in multiple joints, including his knees.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
Upon examination, the child exhibited several symptoms, including pain, swelling, and an inability to walk. Standard blood tests primarily indicated anemia, but X-rays revealed alarming conditions related to scurvy, such as delayed bone age and severe osteopenia. This alarming picture led us to the conclusion that vitamin C deficiency was the underlying culprit behind his knee pain and skeletal issues.
After initiating vitamin C therapy, we noted a remarkable reduction in pain and swelling over the next two months. The child’s condition improved significantly, allowing him to walk again, and follow-up X-rays confirmed the positive changes in his bone health. This case clearly illustrates how vitamin C can effectively alleviate knee pain related to scurvy and reinforces the importance of proper nutrition for overall skeletal health.
9
Reduced knee pain
Most Useful Review
Megavitamin therapy with B50, E400, and protein has effectively reduced the sluggishness in my legs and knees the following day.
Updated: Apr 2026
Liver Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
We evaluated how vitamin C, also known as ascorbic acid, can help protect the liver during procedures that temporarily cut off blood flow—a process known as ischaemia followed by reperfusion. In this study, we used thirty-six male Wistar rats, split into control groups and experimental ones. Each group received the same total dose of vitamin C, administered at different times: either before the ischaemia, before the reperfusion, or both.
Our findings showed that the animals given vitamin C before both the ischaemia and reperfusion had improved outcomes. They had lower levels of liver enzymes, indicating less liver damage, and showed reduced inflammation. Additionally, their portal blood flow was better when compared to the other groups. Overall, our results suggest that administering vitamin C at specific times can significantly reduce liver injury associated with ischaemia-reperfusion.
This study highlights the potential of vitamin C as a protective agent in situations where liver damage is a concern during surgeries or treatments involving blood flow disruption.
Our findings showed that the animals given vitamin C before both the ischaemia and reperfusion had improved outcomes. They had lower levels of liver enzymes, indicating less liver damage, and showed reduced inflammation. Additionally, their portal blood flow was better when compared to the other groups. Overall, our results suggest that administering vitamin C at specific times can significantly reduce liver injury associated with ischaemia-reperfusion.
This study highlights the potential of vitamin C as a protective agent in situations where liver damage is a concern during surgeries or treatments involving blood flow disruption.
9
Enhanced iron absorption
Most Useful Review
This product is excellent, particularly when taken with beef liver pills. It significantly aids in boosting iron levels in the body. I highly recommend it, especially for its role in enhancing iron absorption.
Updated: Mar 2026
Migraine details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
We explored the connection between dietary vitamin C and migraines using data from the National Health and Nutrition Examination Survey (NHANES) that covered several years from 1999 to 2004. In our analysis, we found that 4101 participants reported their migraine experiences, with over 17% indicating they had faced them recently. Using a detailed dietary recall system to assess vitamin C intake, we conducted various statistical analyses to understand the potential effects of vitamin C on migraine occurrence.
What we discovered was quite intriguing: higher dietary vitamin C intake seemed to be associated with a lower likelihood of experiencing migraines. Specifically, our results showed that those in the highest intake category had a significantly reduced risk of migraines compared to those with the lowest intake. The odds ratio indicated that for every increase in vitamin C intake, the likelihood of migraines decreased.
This linear relationship suggests that incorporating more vitamin C-rich foods into our diets could be beneficial for individuals prone to migraines. Our findings indicate that vitamin C may serve as a useful dietary consideration for managing migraine severity and frequency. Overall, these insights could pave the way for further research and highlight the importance of nutrition in migraine management.
What we discovered was quite intriguing: higher dietary vitamin C intake seemed to be associated with a lower likelihood of experiencing migraines. Specifically, our results showed that those in the highest intake category had a significantly reduced risk of migraines compared to those with the lowest intake. The odds ratio indicated that for every increase in vitamin C intake, the likelihood of migraines decreased.
This linear relationship suggests that incorporating more vitamin C-rich foods into our diets could be beneficial for individuals prone to migraines. Our findings indicate that vitamin C may serve as a useful dietary consideration for managing migraine severity and frequency. Overall, these insights could pave the way for further research and highlight the importance of nutrition in migraine management.
9
Effective migraine relief
Most Useful Review
Taking two capsules regularly has normalised my sleep and improved my migraines significantly. When the special effects begin, I ingest the pills and add extra magnesium, which eases the migraine within a couple of hours. Earlier, a migraine would incapacitate me for the entire day. The frequency of my migraines has also diminished, thanks in part to pharmacological support. Regular magnesium intake has alleviated my PMS and periods, reducing irritability and allowing me to get through the first day without painkillers. While I take omega-3, serrapeptase, and resveratrol, I believe magnesium has made a notable impact. Also, using magnesium, lecithin, and protein clearly showcases the benefits of oral collagen. I was truly surprised. I have not experienced any allergies, rashes, or stomach issues. The quality is excellent and the ingredients natural, contributing positively to my health.
Updated: Apr 2025
Pneumonia details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Immunity booster
Most Useful Review
I am prone to pneumonia, so I take this vitamin C daily, usually one piece. At the first sign of a cold, I increase it to two pieces a day. I really like it and have been purchasing it for several years. I'm pleased with the results and recommend it!
Updated: Mar 2025
Common Cold details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
USERS' SCORE
Good
Based on 3 Reviews
8.4
8
We explored how vitamin C affects the severity of common colds through a comprehensive review of available studies. By including only randomized, placebo-controlled trials where participants received at least 1 gram of vitamin C daily, we aimed to investigate both the overall duration of colds and the intensity of symptoms experienced.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
9
Strengthens immune system
Most Useful Review
Our favourite Vitamin C is fantastic during the cold season. It provides a good dosage-to-cost ratio and strengthens my immune system. I purchase it constantly.
Updated: Mar 2026
Herpes details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
USERS' SCORE
Good
Based on 5 Reviews
8.4
9
We explored the effects of ascorbic acid and its derivatives on the replication of Herpes simplex virus type I using human muscle cancer cells.
The study revealed that a specific form of vitamin C, known as 2-O-glycoside of ascorbic acid, showed promising antiviral properties.
Interestingly, while this derivative can inhibit certain chemical reactions involving carbon-centered radicals, it does not impact reactions with oxygen-centered radicals.
However, despite these findings, the overall benefits of vitamin C treatment for herpes remain inconclusive.
The study revealed that a specific form of vitamin C, known as 2-O-glycoside of ascorbic acid, showed promising antiviral properties.
Interestingly, while this derivative can inhibit certain chemical reactions involving carbon-centered radicals, it does not impact reactions with oxygen-centered radicals.
However, despite these findings, the overall benefits of vitamin C treatment for herpes remain inconclusive.
9
Significantly decreased rashes
Most Useful Review
Excellent! I take it in combination with Lysine. Herpes rashes have significantly decreased, and there is no pain at all.
Updated: Mar 2026
Sleep Apnea details
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
Vitamin C improves sleep apnea endothelial function
We evaluated how vitamin C might improve endothelial function in patients with obstructive sleep apnea (OSA). In our study, we compared 10 individuals with untreated OSA to 10 matched control subjects without sleep issues. We measured how well blood vessels reacted to increased blood flow, known as flow-mediated dilation (FMD), using ultrasound before and after administering vitamin C.
Our findings revealed a significant difference: baseline FMD was lower in OSA patients compared to the control group. However, after an intravenous injection of vitamin C, the FMD in OSA patients improved dramatically, reaching levels similar to those seen in the healthy controls. Interestingly, vasoreactivity in the control subjects remained unchanged.
These results suggest that oxidative stress might be a key factor contributing to the endothelial dysfunction experienced by individuals with OSA. The positive response to vitamin C opens up exciting possibilities for exploring antioxidant treatments in managing cardiovascular issues related to OSA.
Our findings revealed a significant difference: baseline FMD was lower in OSA patients compared to the control group. However, after an intravenous injection of vitamin C, the FMD in OSA patients improved dramatically, reaching levels similar to those seen in the healthy controls. Interestingly, vasoreactivity in the control subjects remained unchanged.
These results suggest that oxidative stress might be a key factor contributing to the endothelial dysfunction experienced by individuals with OSA. The positive response to vitamin C opens up exciting possibilities for exploring antioxidant treatments in managing cardiovascular issues related to OSA.
7.5
Improved sleep quality
Most Useful Review
33 people found this helpful
A brilliant vitamin C! It significantly enhances the effects of niacin and melatonin at night and works well with magnesium, vitamins E and D during the day. I have struggled with sleep apnea for over nine years, relying on strong sleeping pills, but since incorporating this vitamin C, I've noticed a marked improvement. Even when it's out of stock, I occasionally purchase an alternative vitamin C that also contains rose hips. I’ll continue using this product indefinitely. Thank you for such a great product!
Updated: Mar 2026
Ulcer details
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.1
USERS' SCORE
Good
Based on 3 Reviews
8.4
9.5
We conducted a double-blind trial involving sixteen individuals with chronic foot ulcers to see how vitamin C impacts their healing. Half of the participants received 500 mg of vitamin C, while the others got a placebo.
After eight weeks, those taking vitamin C showed significant improvement—ulcer healing was much better compared to the placebo group. Notably, everyone who received vitamin C healed without needing amputation, while 44% of the control group did not see any healing.
Our findings suggest vitamin C may be a beneficial treatment for chronic foot ulcers, given its accessibility and low cost.
After eight weeks, those taking vitamin C showed significant improvement—ulcer healing was much better compared to the placebo group. Notably, everyone who received vitamin C healed without needing amputation, while 44% of the control group did not see any healing.
Our findings suggest vitamin C may be a beneficial treatment for chronic foot ulcers, given its accessibility and low cost.
7.5
Effective for ulcers
Most Useful Review
1 people found this helpful
I take 4 tablets daily. I've been using this for a long time due to its large capacity and good cost performance. When I feel unwell, I take one tablet every 30 minutes, and I feel better soon. It is also effective for mouth ulcers. It's like an amulet for me, so it's essential.
Updated: Mar 2026
Anemia details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.9
USERS' SCORE
Good
Based on 6 Reviews
8.3
9
We observed a fascinating phenomenon related to vitamin C and anemia during a series of cases in a prison setting in Ethiopia. Specifically, we examined how scurvy, a disease caused by a lack of vitamin C, contributed to anemia among prisoners.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
Our study focused on ten patients who were admitted for treatment, all of whom presented with some form of leg swelling or pain. After administering vitamin C in the form of ascorbic acid, we noted a significant increase in hemoglobin levels, rising from an average of 4.6 to 7.1 g/dL. This improvement indicates that vitamin C may play a crucial role in alleviating some anemia symptoms when the underlying cause is related to dietary deficiencies.
Additionally, through an observational study involving 67 other patients in the same prison, we confirmed that leg swelling and pain were common symptoms among those affected. With consistent therapeutic doses of vitamin C, all patients showed considerable improvement in their conditions.
Thus, we can conclude that vitamin C does seem to have a valuable effect on anemia caused by dietary deficiencies, particularly in high-risk environments like prisons. This finding encourages healthcare providers to remain vigilant about such nutritional deficiencies and highlights the importance of vitamin C in treatment.
9
Skin condition improved
Most Useful Review
I suffered from rough skin and anemia, so I used vitamin C with iron. Not only has my anemia improved, but my skin has also noticeably calmed down. I will continue taking it!
Updated: Mar 2026
Athlete’s Foot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
Boosts recovery speed
Most Useful Review
My husband and I take vitamin C alongside omega supplements. While we had mild symptoms of COVID for two days, we noticed a significant improvement on the third day after increasing our dose of vitamin C. We take one tablet after breakfast, and if I feel under the weather, I take two. The only downside is that the pill is quite large for me, so I need to break it. My husband manages without any issues!
Updated: Apr 2025
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.3
9
We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
9
Great experience
Most Useful Review
I am pleased with my purchase from iHerb! The vitamin quality is excellent and fairly priced. I've noticed a significant improvement since taking it, and the quick delivery and customer service were commendable. I highly recommend trying it for your needs!
Updated: Mar 2026
Constipation details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 5 Reviews
8.3
8
We conducted a fully decentralized clinical trial to explore the effects of vitamin C on constipation symptoms. Participants who experienced functional constipation were randomly assigned to receive either Lactobacillus with vitamin C or vitamin C alone over a two-week treatment period. The study allowed us to gather data remotely, which is quite innovative and accessible.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.
Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.
Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
9
Very effective
Most Useful Review
1 people found this helpful
Vitamin C provides me with energy. When I'm unwell or have been constipated for 2-3 days, I take a big gulp every 3 hours without taking medication. It’s very effective, and I plan to continue taking it for life. Thank you very much.
Updated: Mar 2026
Influenza details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.3
7
We explored the relationship between vitamin C and influenza, delving into various studies conducted from 2000 to June 2021. In our analysis of the research, we found eleven studies that specifically examined the effects of vitamin C on influenza.
While some of these studies reported positive outcomes, we should note that the isolated benefits of vitamin C can be hard to determine. This is primarily because some studies included additional treatments, making it difficult to draw definitive conclusions about vitamin C alone.
Overall, we observed that while there is some interest and preliminary evidence regarding the efficacy of vitamin C in preventing or treating influenza, its stand-alone effectiveness remains somewhat unclear.
Continued research should help clarify how much vitamin C can truly contribute to combating influenza.
While some of these studies reported positive outcomes, we should note that the isolated benefits of vitamin C can be hard to determine. This is primarily because some studies included additional treatments, making it difficult to draw definitive conclusions about vitamin C alone.
Overall, we observed that while there is some interest and preliminary evidence regarding the efficacy of vitamin C in preventing or treating influenza, its stand-alone effectiveness remains somewhat unclear.
Continued research should help clarify how much vitamin C can truly contribute to combating influenza.
7.5
Vitamin C essential
Most Useful Review
37 people found this helpful
I am astonished that the benefits of Vitamin C are not more widely publicised. After a severe cold last summer, I now supplement with it daily, especially since it may halve the duration of illnesses like influenza. The NOW product meets my expectations perfectly.
Updated: Mar 2026
Leg Cramps details
SCIENTIFIC SCORE
Questionable
Based on 1 Research
5
USERS' SCORE
Good
Based on 3 Reviews
8.3
5
We explored the effects of vitamin C on leg cramps in a group of 60 pregnant women through a double-blind trial. Participants received either calcium or vitamin C (1 g twice daily) as treatment. Our observations revealed that there was no significant difference in clinical improvement between the two treatment groups.
Notably, 14 patients experienced complete relief from symptoms, while 27 reported significant improvement regardless of which treatment they received. Unfortunately, 17 participants found their symptoms unchanged, and only two noticed an increase in leg cramps during the treatment period.
Throughout the study, we measured serum levels of total and ionized calcium, total magnesium, and albumin, but these parameters did not show significant changes in either treatment group. We also didn’t identify any biochemical differences when comparing the effectiveness of vitamin C and calcium for alleviating cramps.
Ultimately, our findings suggest that vitamin C may not be an effective solution for leg cramps in pregnant women, as both treatments yielded similar results with minimal biochemical changes.
Notably, 14 patients experienced complete relief from symptoms, while 27 reported significant improvement regardless of which treatment they received. Unfortunately, 17 participants found their symptoms unchanged, and only two noticed an increase in leg cramps during the treatment period.
Throughout the study, we measured serum levels of total and ionized calcium, total magnesium, and albumin, but these parameters did not show significant changes in either treatment group. We also didn’t identify any biochemical differences when comparing the effectiveness of vitamin C and calcium for alleviating cramps.
Ultimately, our findings suggest that vitamin C may not be an effective solution for leg cramps in pregnant women, as both treatments yielded similar results with minimal biochemical changes.
9
Reduced leg cramps
Most Useful Review
1 people found this helpful
Now Foods C1000 tablets are fantastic! They've helped reduce the fat in my body. I was amazed to find lumps in my legs caused by fat, but now they feel much better, and I feel so much healthier.
Updated: Apr 2026
Menopause details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 2 Reviews
8.3
7
Vitamin C may reduce oxidative stress
We conducted a randomized, double-blind clinical trial to explore the combined effects of resveratrol and vitamin C on oxidative stress in postmenopausal women. The study included forty-six women who faced insulin resistance and were divided into three groups: one received resveratrol alone, another received both resveratrol and vitamin C, and the third group got only vitamin C.
After the treatment, we observed notable results, particularly in the group that took the combination of resveratrol and vitamin C. This group exhibited a significant reduction in harmful oxidative stress markers. For instance, markers like lipohydroperoxides dropped by 33%. Additionally, malondialdehyde levels decreased by remarkable rates in all groups. Group B, which received both antioxidants, showed the most pronounced improvements, including a 39% decrease in protein damage.
While vitamin C showed benefits when combined with resveratrol, it’s crucial to note that the study did not reveal significant differences in insulin resistance among the groups. This finding suggests that while vitamin C may enhance antioxidant capacity and reduce oxidative stress, its isolated effects on menopause-related conditions were not conclusively established. Overall, our study highlights the potential of combining these antioxidants for managing oxidative stress in postmenopausal women.
After the treatment, we observed notable results, particularly in the group that took the combination of resveratrol and vitamin C. This group exhibited a significant reduction in harmful oxidative stress markers. For instance, markers like lipohydroperoxides dropped by 33%. Additionally, malondialdehyde levels decreased by remarkable rates in all groups. Group B, which received both antioxidants, showed the most pronounced improvements, including a 39% decrease in protein damage.
While vitamin C showed benefits when combined with resveratrol, it’s crucial to note that the study did not reveal significant differences in insulin resistance among the groups. This finding suggests that while vitamin C may enhance antioxidant capacity and reduce oxidative stress, its isolated effects on menopause-related conditions were not conclusively established. Overall, our study highlights the potential of combining these antioxidants for managing oxidative stress in postmenopausal women.
7.5
Joint pain relief
Most Useful Review
I use it twice a day. My joint pains reduce during menopause.
Updated: Mar 2026
Osteoporosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.1
USERS' SCORE
Good
Based on 3 Reviews
8.3
8
We explored the connection between vitamin C levels and bone mineral density (BMD) in individuals with diabetes. By examining a group of 74 diabetic patients alongside 26 age-matched non-diabetic controls, we focused on how vitamin C intake could potentially influence bone health. Our goal was to see if higher vitamin C levels were associated with improved BMD and whether this effect might be related to decreases in certain inflammatory markers like VCAM-1 and adiponectin.
The results were quite promising. We observed a positive link between circulating levels of vitamin C and BMD, suggesting that higher vitamin C might indeed contribute to healthier bones. Notably, we found that this beneficial effect was closely tied to lower levels of inflammatory markers in the blood. This indicates that vitamin C might help not just in improving BMD but also in lowering inflammation, which can be particularly valuable for those living with diabetes.
Overall, our findings highlight the importance of maintaining adequate vitamin C levels as a potential strategy to reduce the risk of osteoporosis in individuals with diabetes. Incorporating vitamin C in the diet could be a simple yet effective way to support bone health while also combatting underlying inflammation.
The results were quite promising. We observed a positive link between circulating levels of vitamin C and BMD, suggesting that higher vitamin C might indeed contribute to healthier bones. Notably, we found that this beneficial effect was closely tied to lower levels of inflammatory markers in the blood. This indicates that vitamin C might help not just in improving BMD but also in lowering inflammation, which can be particularly valuable for those living with diabetes.
Overall, our findings highlight the importance of maintaining adequate vitamin C levels as a potential strategy to reduce the risk of osteoporosis in individuals with diabetes. Incorporating vitamin C in the diet could be a simple yet effective way to support bone health while also combatting underlying inflammation.
9
Strengthens bones
Most Useful Review
It is beneficial for those suffering from osteoporosis or joint pain. The formulation contains vitamins and minerals that support overall bone health. The recommended dosage is four capsules daily with meals, ideally split into doses. Personally, I prefer taking it during episodes of pain.
Updated: Apr 2025
Tendonitis details
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
USERS' SCORE
Good
Based on 5 Reviews
8.3
9
We explored the effect of vitamin C on tendon cell degeneration, aiming to find out if it could be an effective treatment for tendinitis. The study involved human-derived tendon cells exposed to oxidative stress, simulating the conditions of tendinopathy. By applying various doses of ascorbic acid, we observed a significant reduction in cell death and oxidative stress in the groups that received vitamin C treatment.
Interestingly, we noted that while both lower and higher vitamin C doses helped with cell survival, the higher dose of 30 mM proved especially effective. It not only preserved the cytoskeletal structure of the tendon cells but also inhibited the expression of a marker linked to aging and degeneration. This suggests that high-dose vitamin C could play a vital role in supporting tendon health and recovery from damage.
In summary, our findings indicate that high-dose vitamin C is a promising option for mitigating tendon cell degeneration. This could provide a new avenue for those suffering from tendinopathy, offering hope for recovery and improved tendon function.
Interestingly, we noted that while both lower and higher vitamin C doses helped with cell survival, the higher dose of 30 mM proved especially effective. It not only preserved the cytoskeletal structure of the tendon cells but also inhibited the expression of a marker linked to aging and degeneration. This suggests that high-dose vitamin C could play a vital role in supporting tendon health and recovery from damage.
In summary, our findings indicate that high-dose vitamin C is a promising option for mitigating tendon cell degeneration. This could provide a new avenue for those suffering from tendinopathy, offering hope for recovery and improved tendon function.
9
Enhances immune response
Most Useful Review
Wonderful! Vitamin C with bioflavonoids for better absorption! A generous dosage of 1000 mg! It acts as an antioxidant, providing protection against free radicals, and supports collagen synthesis for critical tissues including blood vessels and tendons. It enhances the immune system's ability to combat inflammatory diseases, stimulates white blood cell production, and promotes quicker wound healing. Additionally, it aids iron absorption and supports cardiovascular health.
Updated: Apr 2025
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 10 Reviews
8.2
8
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
9
Effective vitamin C
Most Useful Review
21 people found this helpful
A life saver for people with allergic rhinitis! I suffered for years until I discovered that Vitamin C was the remedy for me. I prefer drinking freshly squeezed orange or grapefruit juice, but it’s impractical every day. When my nose starts to feel stuffed, I take a couple of Vitamin C tablets and feel better the next day. If I have a terrible sinus headache, I take 3 or 4 tablets at night and wake up headache-free. This vitamin was incredibly helpful during our January trip to Switzerland.
Updated: Mar 2026
Blurred Vision details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.2
7.5
Vision improvement noted
Most Useful Review
Plays a significant role in the formation of fibrillar protein - collagen, which underpins the connective tissue of the body. It provides strength and durability to bones. Moreover, it aids in the faster absorption of iron, thus helping to avoid anaemia. It enhances immunity by increasing the production of leukocytes, which fight microorganisms and foreign structures. Furthermore, it improves the absorption of plant-based iron, essential in preventing glandular anaemia that can lead to lethargy and impaired attention. In children, a deficiency in Vitamin C may result in cognitive delays. It also helps to prevent blurred vision associated with aging.
Updated: Apr 2025
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 6 Reviews
8.2
7
We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
9
General wellbeing improved
Most Useful Review
2 people found this helpful
I take one tablet with a meal, pairing it with folic acid for better absorption. After two weeks, I’ve noticed improved wellbeing, much less fatigue, and renewed energy for activities like swimming and jogging. I’m extremely pleased with the results!
Updated: Mar 2026
Diabetes details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 3 Reviews
8.2
8
We examined the effects of vitamin C supplementation on diabetes, focusing specifically on glycemic control and insulin resistance. Our analysis included a comprehensive review of fourteen systematic reviews and meta-analyses that assessed five different water-soluble vitamins: B-1, B-3, biotin, B-9 (folic acid), and C.
The findings revealed that vitamin C can significantly improve glycemic control in individuals with type 2 diabetes. We noticed reductions in fasting blood glucose levels and HbA1c, especially when supplementation lasted longer than 30 days. This is promising news for those managing diabetes, as it suggests that incorporating vitamin C could be beneficial.
Furthermore, we found that folic acid also plays a role in improving insulin resistance. However, there is a clear need for more well-designed randomized controlled trials to solidify these findings and develop a deeper understanding of the relationship between water-soluble vitamins and diabetes management.
The findings revealed that vitamin C can significantly improve glycemic control in individuals with type 2 diabetes. We noticed reductions in fasting blood glucose levels and HbA1c, especially when supplementation lasted longer than 30 days. This is promising news for those managing diabetes, as it suggests that incorporating vitamin C could be beneficial.
Furthermore, we found that folic acid also plays a role in improving insulin resistance. However, there is a clear need for more well-designed randomized controlled trials to solidify these findings and develop a deeper understanding of the relationship between water-soluble vitamins and diabetes management.
7.5
Effective diabetes control
Most Useful Review
I purchased this for a friend with severe diabetes, and it helped her manage her diabetes effectively. She mentioned the package size was excellent and lasted her nearly a year. The capsules are easy to swallow alongside other supplements.
Updated: Mar 2026
Flu details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.5
USERS' SCORE
Good
Based on 260 Reviews
8.2
8
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
7.5
Reduced sickness frequency
Most Useful Review
254 people found this helpful
Ascorbic acid is a vitamin that our bodies cannot create, hence we need to obtain it from food. A lack of proper nutrition can lead to a deficiency. It aids in various metabolic processes, enhances resistance to infections, and supports tissue regeneration. For treating vitamin C deficiency, a daily intake of 1000 mg is recommended. I experienced no allergic reactions or side effects, and I found I was less ill and endured colds and flu more easily. I highly recommend it.
Updated: Mar 2026
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.2
7.5
Sustained release works
Most Useful Review
1 people found this helpful
I bought this for managing my physical condition, as I thought I lacked vitamin C in my diet. It appears effective, especially when taken with vitamin E. Since I started drinking it, it has evidently worked for spots and swelling. My physical condition has improved, and I will continue taking it. I believe its sustained release form is very efficient.
Updated: Apr 2026
Whooping Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.2
7.5
Reduced coughing
Most Useful Review
1 people found this helpful
I bought this for my son, who had a strong cough. Even during the initial intake, his cough decreased significantly, prompting me to order it again.
Updated: Apr 2025
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 1455 Reviews
8.1
7
Effectiveness of Vitamin C on Colds
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
9
Quick cold relief
Most Useful Review
233 people found this helpful
At the first sign of a cold or SARS, I take 3-4 capsules per day. I start feeling normal within 2-3 days. In winter and during respiratory disease season, vitamin C is crucial for health. I recommend it wholeheartedly!
Updated: Apr 2025
Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 23 Reviews
8.1
7.5
Essential during colds
Most Useful Review
5 people found this helpful
Irreplaceable during colds. This vitamin C has the correct dosage. In the off-season, when everyone is sneezing, coughing, and sniffling, it is essential. If I notice the first signs of a cold, I double the dosage to fend off symptoms. I've tried this multiple times and it works. Additionally, it contains bioflavonoids that help with absorption. Thus, I have reason to give it five stars.
Updated: Apr 2025
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.1
8
This study aimed to understand how dietary vitamin C affects depression in adults. By analyzing data from the National Health and Nutrition Examination Survey spanning from 2005 to 2020, we focused on the relationship between vitamin C intake and depression levels among 38,157 participants.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
Our findings revealed that individuals who consumed higher amounts of vitamin C had lower odds of experiencing depression. Specifically, those in the higher intake quartiles showed significantly reduced odds compared to those with the lowest intake. Interestingly, we discovered an L-shaped curve representing the relationship between vitamin C and depression, suggesting that while increased intake was beneficial up to a certain point (around 93.61 mg), higher consumption did not yield additional benefits.
While our results are promising, it's crucial to note that this was a cross-sectional study, meaning we cannot definitively claim that vitamin C intake causes changes in depression. Additionally, other factors might have influenced these associations, which we couldn't fully control for.
Overall, this research provides intriguing evidence of the potential role that dietary vitamin C might play in alleviating depressive symptoms, especially for those consuming lower amounts.
7.5
No more depression
Most Useful Review
A very good product. I have been taking three tablets a day for a month now. Due to the pandemic, the lingering runny nose has dissipated, I find it easier to wake up in the morning, and there is no lingering depression in winter. I am very pleased with this product.
Updated: Mar 2026
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.1
7.5
Improved bowel movements
Most Useful Review
5 people found this helpful
Repeat many times. My 75-year-old parents experience constipation. I suggested they take 3 to 4 capsules daily. I understood that the dosage is significant, so I suggested it be taken with half a kitchen knife. Their bowel movements are improving.
Updated: Apr 2025
Sore Throat details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 24 Reviews
8.1
7.5
Strengthens immunity
Most Useful Review
13 people found this helpful
Why Now Foods? I chose this product on the advice of my endocrinologist: "The firm is proven, the quality is excellent, there are no unnecessary additives, unlike any fizzy that is sold in our pharmacies." I noticed strengthening immunity quickly, as I usually start sneezing and feel a sore throat even from a slight draft; vitamin C is incredibly helpful. Additionally, I've experienced an improvement in my emotional state: I have more energy, find it easier to rise in the morning, and feel better at work and school. I've been combining vitamin C with vitamin D - also from Now Foods. I really like this company and plan to continue ordering from them.
Updated: Apr 2025
Gastritis details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.7
USERS' SCORE
Good
Based on 3 Reviews
8
8
We aimed to discover how vitamin C supplementation affects oxidative stress in individuals diagnosed with chronic gastritis. In this study, we looked at 244 Japanese patients suffering from atrophic gastritis. They were randomly assigned to receive either 50 mg or 500 mg of vitamin C every day for five years.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
After analyzing the results, we found notable differences between the two groups. The high-dose group experienced a significant decrease in reactive oxygen species (ROS), suggesting that vitamin C may help reduce oxidative stress associated with chronic gastritis. In contrast, the low-dose group reported an increase in ROS levels. These findings prompt further interest in how vitamin C can protect against oxidative stress in similar conditions.
Overall, our study supports the idea that higher doses of vitamin C could have a beneficial effect on oxidative stress, particularly in those dealing with gastritis. This insight opens avenues for considering vitamin C as a potential supportive treatment for managing oxidative stress-related issues in digestive health.
9
No gastritis issues
Most Useful Review
I find this product good as it does not trigger any gastritis for me, and I have not fallen ill.
Updated: Mar 2026
Pelvic Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8
9
Decreased pelvic pain
Most Useful Review
Very good; I've been taking this for about a month and a half, and I've noticed a difference in my health. I've become more active, and my pelvic pain has lessened. I hope to see even more results with continued use. It’s gentle on the stomach, and the pill is a normal size, making it easy to swallow. I highly recommend this brand, having purchased vitamins and supplements from them several times.
Updated: Mar 2025
Adrenal Gland Disorder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.9
9
Cool support effect
Most Useful Review
I tried vitamin C to support my adrenal glands, and overall, I experienced a remarkable effect.
Updated: Apr 2025
Cancer details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.9
9
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
8
Cancer progress halted
Most Useful Review
2 people found this helpful
Best choice! It is an essential supplement for my husband, who doesn't enjoy sour fruits. I discovered my cancer last year, and I believe this supplement has inhibited its progression. I am pleased to take it as it has a time-release formula. Furthermore, it is quite affordable in Japan. Thank you!
Updated: Apr 2026
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.6
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.8
9
In our recent study, we set out to explore the effectiveness of a 5% sodium L-ascorbyl-2-phosphate lotion, a stable form of vitamin C, for treating acne. We conducted a double-blind, controlled trial with 50 participants over 12 weeks, where half used the vitamin C lotion and the other half received a placebo.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.
The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.
Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
9
Acne largely controlled
Most Useful Review
5 people found this helpful
Keeps my acne at bay!!! This product is a holy grail for managing my acne. While I attempt to maintain a healthy diet, I still experience back acne. However, since taking 2000-4000 mg of vitamin C daily, my skin remains 90% clear. I do get occasional acne just before my period, but I used to break out daily; this has truly cured a significant issue for me!
Updated: Apr 2026
Insomnia details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.7
9
Vitamin C alleviates chemotherapy insomnia
We explored the effects of pharmacologic vitamin C on insomnia related to cancer chemotherapy. In our case study, we worked with a woman battling recurrent breast cancer who was experiencing significant fatigue and lethargy as she underwent weekly chemotherapy sessions.
To combat her sleep disturbances, we administered high doses of vitamin C, 50 grams per session, twice a week. We also employed quality of life and fatigue questionnaires to monitor changes over time.
The results were promising! We observed marked improvements in her insomnia and overall fatigue levels. Furthermore, there was a notable enhancement in her cognitive functioning, without any adverse side effects from the vitamin C treatment.
This case highlights how vitamin C may offer relief from insomnia associated with chemotherapy, providing a new avenue for improving quality of life during cancer treatment.
To combat her sleep disturbances, we administered high doses of vitamin C, 50 grams per session, twice a week. We also employed quality of life and fatigue questionnaires to monitor changes over time.
The results were promising! We observed marked improvements in her insomnia and overall fatigue levels. Furthermore, there was a notable enhancement in her cognitive functioning, without any adverse side effects from the vitamin C treatment.
This case highlights how vitamin C may offer relief from insomnia associated with chemotherapy, providing a new avenue for improving quality of life during cancer treatment.
9
Fall asleep quicker
Most Useful Review
I initially bought vitamin C for general use, but I’ve discovered that taking it before bed helps me with my insomnia. My difficulty falling asleep has been a long-standing issue, and combining it with vitamin C clearly aids me in drifting off to sleep more easily and improving my overall rest.
Updated: Apr 2025
Nausea details
SCIENTIFIC SCORE
Very Likely Ineffective
Based on 1 Research
2
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.7
2
Vitamin C ineffective against nausea
We explored the effects of vitamin C as a treatment for nausea and vomiting in pregnancy, also known as emesis gravidarum. Our study involved 111 participants, who were given either vitamin C-containing chewing gum, a placebo, or no treatment at all. We monitored them over two follow-up visits in early pregnancy to assess their symptoms.
While we measured various factors that could influence nausea—including hormone levels like hCG and DAO—our findings showed that the chewing gum did not effectively reduce nausea symptoms compared to the placebo or no treatment. Specifically, the vitamin C gum was not associated with any significant alleviation of nausea or vomiting.
Interestingly, we found that elevated levels of hCG were linked to increased nausea severity. In contrast, higher levels of DAO appeared to have a protective effect against symptoms. Additionally, elevated thyroxine and pyridoxine levels correlated with worsened nausea.
Overall, while vitamin C is often highlighted for its health benefits, our results suggest it does not play a significant role in treating nausea during pregnancy. This study highlights the complexities behind nausea in pregnancy, indicating that further research is necessary to uncover effective treatment options.
While we measured various factors that could influence nausea—including hormone levels like hCG and DAO—our findings showed that the chewing gum did not effectively reduce nausea symptoms compared to the placebo or no treatment. Specifically, the vitamin C gum was not associated with any significant alleviation of nausea or vomiting.
Interestingly, we found that elevated levels of hCG were linked to increased nausea severity. In contrast, higher levels of DAO appeared to have a protective effect against symptoms. Additionally, elevated thyroxine and pyridoxine levels correlated with worsened nausea.
Overall, while vitamin C is often highlighted for its health benefits, our results suggest it does not play a significant role in treating nausea during pregnancy. This study highlights the complexities behind nausea in pregnancy, indicating that further research is necessary to uncover effective treatment options.
10
No nausea experienced
Most Useful Review
For the price, the quality is excellent! I took samples at first, and I really liked it. There was no nausea.
Updated: Apr 2025
Diarrhea details
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.5
9
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
9
No discomfort noted
Most Useful Review
6 people found this helpful
Recommended for mega ease of opening the container, and there's no burden on the stomach when you drink. The time-release formulation contains a 1000mg combination that works well. I took one tablet at an hourly rate, and thankfully, I didn't experience any stomach aches or diarrhoea. The tablets are large but smooth, making them easy to swallow with a bit of care regarding their orientation.
Updated: Mar 2026
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 71 Reviews
7.4
7.5
Quick relief
Most Useful Review
3 people found this helpful
This is the best vitamin C I’ve ever taken! When I came down with a sore throat and swollen lymph nodes, I took one tablet, and in a few hours, the symptoms started to fade. I continued taking it, and I didn’t need to monitor my condition. It helped me effectively manage my adenoiditis symptoms.
Updated: Apr 2025
Heartburn details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.3
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
9
No heartburn
Most Useful Review
86 people found this helpful
NOW brand doesn't give my wife heartburn or acid reflux, unlike other vitamin C brands we’ve tried. We have been using it for a while now and she hasn’t had any issues. The tablets are manageable to swallow, and I believe that taking vitamin C is why I haven't fallen ill recently. I take two a day, which I find beneficial.
Updated: Mar 2026
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 13 Reviews
7.2
7.5
Strengthens immune system
Most Useful Review
12 people found this helpful
This product remarkably strengthens the immune system and bones, helping absorb folic acid. The tablets are large; my husband and I take them twice daily. We're very pleased with the effects, particularly in reducing bone pain. Highly recommended for everyone!
Updated: Apr 2025
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.1
7.5
Rash improvement
Most Useful Review
9 people found this helpful
My skin is problematic, with frequent rashes. Hence, as per my doctor’s recommendation, I purchased this particular Vitamin C with an excellent formulation. It’s a brilliant vitamin; I take it daily with food. After taking the gland, I have Vitamin C some ten minutes later to ensure good iron absorption. My skin feels noticeably firmer, and the rash has lessened.
Updated: Apr 2025
Chest Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 13 Researches
8.3
USERS' SCORE
Moderately Good
Based on 7 Reviews
7
9
We explored the effects of vitamin C on chest pain in chronic smokers experiencing endothelial dysfunction. In our study, 31 patients, who were undergoing diagnostic catheterization without significant coronary artery issues, participated in a controlled trial. They were given either an IV infusion of 3 grams of ascorbic acid (vitamin C) or a placebo saline solution before undergoing a cold pressor test to assess their coronary artery response.
The results were telling. Smokers typically showed a decrease in luminal area—an indicator of blood flow—during the cold pressor test. However, after infusing vitamin C, this response shifted positively, demonstrating improved blood flow through a vasodilation effect. On the other hand, those who received the placebo did not experience significant changes.
This means that for chronic smokers, acute administration of vitamin C appears to enhance the function of the endothelium, which is vital for proper blood vessel health and managing chest pain. Ultimately, we observed that vitamin C may help prevent the inactivation of nitric oxide, a compound that supports healthy blood flow, and this effect could be crucial for managing cardiovascular health in smokers.
The results were telling. Smokers typically showed a decrease in luminal area—an indicator of blood flow—during the cold pressor test. However, after infusing vitamin C, this response shifted positively, demonstrating improved blood flow through a vasodilation effect. On the other hand, those who received the placebo did not experience significant changes.
This means that for chronic smokers, acute administration of vitamin C appears to enhance the function of the endothelium, which is vital for proper blood vessel health and managing chest pain. Ultimately, we observed that vitamin C may help prevent the inactivation of nitric oxide, a compound that supports healthy blood flow, and this effect could be crucial for managing cardiovascular health in smokers.
9
No pain experienced
Most Useful Review
I was initially concerned due to mild chest pain from vitamin C previously, but this one did not cause any discomfort. The pills are large and thick; I sometimes crush them to mix with drinks, which can be a nuisance. I try to avoid taking it excessively.
Updated: Apr 2025
Kidney Stones details
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
6.9
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.5
4
We examined the relationship between vitamin C intake and the risk of developing kidney stones in a large cohort. This study included a significant number of participants: 156,735 women from the Nurses' Health Studies and 40,536 men from the Health Professionals Follow-up Study.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
0
Kidney stone risk
Most Useful Review
It's crucial to review clinical studies on vitamin C, as I previously thought large doses had no side effects. I learnt that excess vitamin C might contribute to kidney stones, so I've started dividing the capsules for safer consumption.
Updated: Mar 2026
Data last updated:
