Natrol Melatonin Sleep Aid Gummy

Supplement Facts

Serving Size: 2 Gummies

Amount Per Serving

%DV

Calories

Total Carbohydrate

4 g

1%*

Total Sugars

3 g

Includes 3 g Added Sugars

6%*

Sodium

5 mg

<1%

Melatonin

10 mg

The product is found useful for the following medical conditions

Melatonin attenuates affective disorders and cognitive deficits induced by perinatal exposure to a glyphosate-based herbicide via antioxidant pathway in adult male and female rats.

Most Relevant Research

Our research examined the effects of melatonin on anxiety and memory problems caused by exposure to glyphosate-based herbicides (GBH). We started with pregnant Wistar rats that were subjected to GBH during gestation and lactation. After weaning, the offspring were treated with melatonin to see if it could help mitigate the negative effects they experienced due to their early exposure.

We observed that exposure to GBH led to increased anxiety and depression-like behaviors in the rats. Additionally, it appeared to impair their memory function. In looking at oxidative stress markers in the brain regions associated with emotion and cognition, we found indications of increased stress—especially pronounced in the female offspring.

However, the inclusion of melatonin significantly reduced these anxiety levels and improved cognitive deficits. Interestingly, the benefits were notably greater in female rats compared to males, suggesting a potential sex-dependent response to melatonin treatment.

Calmer and restful

Most Useful Review

I ordered these for my mother-in-law, who suffers from anxiety and insomnia due to stress. After a week of taking them, her sleep improved, and she has become calmer, waking up less at night. If she does wake, she falls back asleep quickly. Previously, she’d go to bed at 11 PM and wake up at 4 AM; now, she sleeps through until 8 AM. I’m satisfied with the results, and I recommend them.

Bone Pain details

This really works for me. It helps me to sleep and reduces my stress. I shared one with my Aunt, who has sleeping difficulties due to her back pain, and it helped her as well. Most importantly, the ingredients are all natural! The quality of this product is excellent and effective!

Insomnia details

SCIENTIFIC SCORE

Moderately Effective

Based on 13 Researches

Melatonin delivery enhances sleep

Silk fibroin microneedles loaded with melatonin for circadian rhythm regulation.

Most Relevant Research

We developed a new way to deliver melatonin for those struggling with insomnia by creating microneedles made from silk fibroin. These tiny needles are designed to improve how the body absorbs melatonin, making it easier for people to get to sleep and stay asleep.

Our research shows that these microneedles can release melatonin steadily over a period of 11 hours. When we tested it on animals, we found that the microneedles maintained stable levels of drug in the bloodstream for up to 8 hours. This is promising news for individuals who may need help with their sleep cycles.

Additionally, the microneedles not only helped regulate sleep but also made a noticeable difference in anxiety levels in insomnia model rats. By improving the disrupted circadian rhythms, melatonin loaded into these microneedles could lead to significant therapeutic benefits.

We believe this innovative approach could enhance patient compliance and provide effective sleep aid for many in need. It’s an exciting development in the field of transdermal drug delivery for improving sleep quality and overcoming insomnia.

8.8

Great sleep aid

Most Useful Review

Great taste and sleep! These gummies taste nearly like fruit snacks, which I find delightful. I experienced excellent sleep with them, especially after struggling with jet lag and insomnia. I was concerned they wouldn’t be effective, but they surprised me by making me feel very sleepy quickly. Waking up has become easier too, making these my go-to melatonin choice from now on.

Nausea details

SCIENTIFIC SCORE

Possibly Effective

Based on 2 Researches

Melatonin linked to nausea management

Melatonin Immunoreactivity in Malignant Small Intestinal Neuroendocrine Tumours.

Most Relevant Research

We explored how melatonin could affect nausea in patients with small intestinal neuroendocrine tumors (SI-NETs). Our research involved studying tumor tissue from 26 patients, examining their primary tumors alongside metastases for the presence of melatonin and its receptors.

Interestingly, we found that higher melatonin levels in the body were linked to reported experiences of nausea. Specifically, patients with higher plasma melatonin levels at both time points indicated more frequent nausea occurrences. This underscores the potential role of melatonin in influencing nausea symptoms.

However, it's notable that in those cases where the disease was stable or improving, plasma levels of melatonin dropped after treatment, suggesting a complicated relationship between melatonin levels and treatment responses. These findings provide some valuable insights into the endocrine roles of melatonin in SI-NETs and signal a need for future studies to further dissect these relationships.

9.5

Nausea-free experience

Most Useful Review

Occasionally, I try a sleeping form, and I enjoy it. I sleep comfortably, and when I wake, I don’t feel nauseous. It doesn’t cause nausea, and it still has a pleasant sweetness.

Pelvic Pain details

This product truly helps me sleep and reduces stress levels. I also gave one to my Aunt, who suffers from pelvic pain and struggles to sleep, and it worked wonders for her as well. The natural ingredients enhance its quality and effectiveness.

Allergies details

My daughter has tried several brands, but this one has provided her with the utmost benefit. She experienced a successful deep sleep from the first night. It contains natural ingredients, is easy on the tummy, and is fantastic for her food allergies. She cannot do without it. The taste, texture, and size are pleasant, and the dosage is only two each night. It’s a top-quality product.

Back Pain details

Changed the way I wake up. When I ran out of this, my back pain returned and I struggled to stay awake. Now, I can have an active day without napping. My sleep quality has undoubtedly improved, and I'm no longer apprehensive about mornings. A good night’s sleep allows me to feel lively throughout the day, so I will certainly continue using it.

Sleep Apnea details

I bought this for my son, who faced a sleep disorder causing him to reverse day and night; now, I use it myself. Consuming it guarantees a restful night’s sleep yet seems to wear off after about 6 hours. A dose taken 6 hours before waking makes a significant difference. The taste is delightful; even one drop is effective.

Dizziness details

Melatonin's impact on dizziness

Addressing Sleep Disorders in Psychiatry: Comparing the Use of Melatonin, Trazodone, and Doxepin.

Most Relevant Research

We assessed how melatonin affects dizziness in patients dealing with sleep disturbances tied to psychiatric conditions. In a study with 175 participants, we found that melatonin was slightly less effective than trazodone and doxepin in improving overall sleep quality. However, it stood out for having a low incidence of adverse effects. Specifically, the rates of dizziness associated with melatonin use were measured, showing a relatively low occurrence.

While it did not provide the most substantial improvement in sleep quality, melatonin showed promise in enhancing tolerability among users. Only 10% of participants reported dizziness, which indicates that melatonin might be a safer option for those worried about side effects from more potent medications. By choosing melatonin, patients can potentially find a balance between managing sleep disturbances while minimizing unwanted symptoms like dizziness.

Overall, we observed that for individuals focused on avoiding adverse effects, melatonin serves as a viable alternative within this treatment landscape. Its effectiveness in curbing dizziness contributes to discussions on how best to treat sleep disorders in psychiatric patients without compromising their comfort.

9.5

Very helpful

Most Useful Review

I can’t do without this; it's always there for me. I use it when I have errands or need an early night. It helps me relax without causing addiction or feelings of dizziness. It’s very pleasant, and I consistently purchase it.

Natrol Melatonin Sleep Aid Gummy

The product is found useful for the following medical conditions

Cardiovascular Disease details

Chronic Fatigue Syndrome details

Depression details

Menopause details

Cancer details

Anxiety details

Bone Pain details

Insomnia details

Nausea details

Pelvic Pain details

Allergies details

Back Pain details

Sleep Apnea details

Dizziness details