Nature Made Iron
Buy on Amazon
Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Iron (as ferrous sulfate)
65 mg
361%

The product is found useful for the following medical conditions

Anemia details

SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.6
USERS' SCORE
Good
Based on 31 Reviews
8.9
9.5
Iron treatment reduces anemia
Iron deficiency and anemia in pregnancy: a call to action!: -"If you don't take a temperature, you can't find a fever".
Most Relevant Research
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.

Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.

However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
9.5
Best brand found
Most Useful Review
I had been dealing with chronic, sometimes severe anaemia and tried various prescription supplements that caused nausea. Eventually, I discovered these Nature Made iron supplements, which have no side effects. After sufficient time, I no longer feel the effects of anaemia, and my lab results often show normal ranges. I've found that taking one pill every other day maintains my health effectively. If others have not worked for you or made you feel ill, consider giving this brand a try.

Nausea details

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.7
9
FCH reduces nausea in IDA treatment
A Multicenter Single-Arm Study of Switching to Ferric Citrate Hydrate for Iron Deficiency Anemia in Patients Intolerant to Oral Iron: RIO-SWITCH.
Most Relevant Research
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.

Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
9.5
No nausea experienced
Most Useful Review
Better than prescription iron! I have chronic anemia and had been using prescription supplements, which caused nausea. After trying various other brands, I found these from Nature Made to have no nausea or upset stomach. With consistent use, my iron levels improved, and I can now take one pill every other day to maintain my health.

Bone Pain details

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Alendronate reduces pain and improves BMD
The efficacy of alendronate for the treatment of thalassemia-associated osteoporosis: a randomized controlled trial.
Most Relevant Research
We explored the effectiveness of alendronate, a common drug for osteoporosis, in treating bone pain and improving bone health in patients with thalassemia. This randomized controlled trial involved men and premenopausal women, who were given either alendronate or a placebo for 12 months.

We found that alendronate significantly improved bone mineral density and reduced back pain. Even better, the treatment was well tolerated with a good safety profile. Overall, our findings suggest that alendronate can be beneficial for those struggling with osteoporosis linked to thalassemia.
9.5
Effective pain relief
Most Useful Review
I take these every month during my period, and they effectively alleviate my bone pain and reduce the symptoms. Thank you very much.

Leg Cramps details

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 3 Reviews
8.6
7
Iron treatment improves leg cramps
Iron deficiency associates with deterioration in several symptoms independently from hemoglobin level among chronic hemodialysis patients.
Most Relevant Research
We explored the effects of iron deficiency (ID) in patients on maintenance hemodialysis, especially regarding common symptoms like leg cramps. The study included 154 patients, all of whom had reached target hemoglobin levels, which means they were not anemic. This allowed us to focus on the impact of ID without the confounding factor of low hemoglobin.

Our findings revealed that patients with iron deficiency reported a higher severity of leg cramps compared to those without ID. Specifically, we observed that a low transferrin saturation (TSAT) level contributed significantly to the experience of pain during vascular access punctures and those annoying intradialytic leg cramps. Additionally, patients with lower ferritin levels faced more intense issues like severe fatigue and headaches during their dialysis sessions.

The results suggest that treating iron deficiency could potentially alleviate these critical symptoms, indicating that proactive iron supplementation may be beneficial for those undergoing maintenance dialysis. Addressing ID might not only improve hemoglobin levels but also enhance overall quality of life by reducing painful experiences like leg cramps.
9.5
Effective treatment
Most Useful Review
Value for money and a supplement that genuinely works! I recently bought Nature Made Iron for my iron deficiency and was thoroughly impressed by the quality of ingredients and how quickly I noticed results in my body, mind, and mood. The composition and packaging are excellent. Previously, I suffered from weakness, muscle cramps, and fatigue; however, after taking these tablets, I've noticed a tremendous change. I feel fit, active, and energetic. I wholeheartedly recommend Nature Made Iron as a brilliant supplement that truly works!

Autoimmune Disorder details

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 3 Reviews
8.3
8
CUR-PDT triggers ferroptosis in RA
CUR-PDT induces ferroptosis of RA-FLS via the Nrf2/xCT/GPX4 pathway to inhibit proliferation in rheumatoid arthritis.
Most Relevant Research
We examined how curcumin-mediated photodynamic therapy (CUR-PDT) induces a specific type of cell death called ferroptosis in fibroblast-like synoviocytes from rheumatoid arthritis patients.

Using a rat model, we monitored joint swelling and inflammation while analyzing key proteins involved in this process. The results indicated that CUR-PDT successfully reduces harmful cell growth and inflammation in RA cells by targeting the Nrf2-xCT-GPX4 pathway.

This finding emphasizes the potential of CUR-PDT as a treatment strategy in managing rheumatoid arthritis.
9
Enhanced well-being
Most Useful Review
The quality is superb. I ordered it for my pregnant friend, and she is thrilled with the results. The taste is pleasant and easy to swallow, and she noticed improved overall well-being and energy after a few months. I recommend it to all expectant mothers.
image