Supplement Facts
Serving Size: 2 Soft Gels
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%
Saturated Fat
0 g
0%
Trans Fat
0 g
†
Vitamin D3 (cholecalciferol)
10 mcg (400 IU)
67%
Total Omega-3s♦
830 mg
†
EPA (Eicosapentaenoic Acid)
205 mg
†
DHA (Docosahexaenoic Acid)
480 mg
†
The product is found useful for the following medical conditions
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 28 Researches
7.5
USERS' SCORE
Good
Based on 5 Reviews
8.8
9.5
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
10
Headache relief
Most Useful Review
12 people found this helpful
Very good supplement! I started taking fish oil during my second trimester after experiencing frequent headaches. Remarkably, within a month of taking it, I only had one headache! This really is a miracle for me. It's rather pricy, but it works well.
Allergies details
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.9
USERS' SCORE
Good
Based on 14 Reviews
8.6
We uncovered intriguing insights into how eicosapentaenoic acid (EPA) and its metabolite, 12-hydroxyeicosapentaenoic acid (12-HEPE), play a role in managing allergic responses, particularly in the skin. Our study revealed that when mice consumed an omega-3 fatty acid-rich diet, 12-HEPE became a significant metabolite in their skin.
Interestingly, we observed that the enzymes responsible for producing 12-HEPE were more active in the skin compared to other organs. This effective metabolite appeared to reduce inflammation caused by contact hypersensitivity. Specifically, we found that applying 12-HEPE topically limited the influx of neutrophils, a type of white blood cell involved in inflammatory responses.
Taking our research a step further, we investigated the effects of 12-HEPE on human skin cells, or keratinocytes, in lab conditions. Our findings showed that 12-HEPE inhibited two specific genes that cause neutrophils to be attracted to the site of inflammation, showcasing its potential as a therapeutic agent for allergy management. Overall, we identified 12-HEPE as a potent metabolite in the skin, suggesting that dietary omega-3 fatty acids could be a beneficial strategy in controlling allergic reactions.
Interestingly, we observed that the enzymes responsible for producing 12-HEPE were more active in the skin compared to other organs. This effective metabolite appeared to reduce inflammation caused by contact hypersensitivity. Specifically, we found that applying 12-HEPE topically limited the influx of neutrophils, a type of white blood cell involved in inflammatory responses.
Taking our research a step further, we investigated the effects of 12-HEPE on human skin cells, or keratinocytes, in lab conditions. Our findings showed that 12-HEPE inhibited two specific genes that cause neutrophils to be attracted to the site of inflammation, showcasing its potential as a therapeutic agent for allergy management. Overall, we identified 12-HEPE as a potent metabolite in the skin, suggesting that dietary omega-3 fatty acids could be a beneficial strategy in controlling allergic reactions.
9
Highly recommend DHA
Most Useful Review
15 people found this helpful
Good way to promote brain and eye health! I took 2 capsules daily throughout pregnancy and now during breastfeeding so my baby gets adequate DHA. This is recommended to reduce issues like allergies, eczema, and attention deficit disorders in children. Highly recommend this product.
Blurred Vision details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.6
9
Supports brain development
Most Useful Review
30 people found this helpful
Great omega! An excellent prenatal omega with vitamin D3. It maintains proper DHA levels in pregnant and lactating women, supporting the development of children's brains and vision. The capsules contain DHA-480 mg, EPA-205 mg, and vitamin D3 -400 IU. Although you may detect a fish smell upon opening, there is no fishy aftertaste. They are small and easy to swallow. Each batch is tested by a third-party laboratory for toxins, including heavy metals, and inspection certificates can be provided upon request. All fish oil is in triglyceride form.
Heartburn details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.6
9
No heartburn experienced
Most Useful Review
300 people found this helpful
As always, excellent quality; I haven't experienced heartburn or belching. For those wanting to conceive, I highly recommend this omega.
Arthritis details
SCIENTIFIC SCORE
Possibly Effective
Based on 38 Researches
7.4
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
We explored the effects of eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, on patients with rheumatoid arthritis (RA). This analysis gathered data from eighteen randomized controlled trials involving over a thousand RA patients, ensuring a comprehensive look at its impact.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement.
9
Relief for arthritis
Most Useful Review
Omega strengthens the immune system, normalises metabolism, and helps manage mental stress. It has also prevented osteoporosis, supported joint health, and alleviated pain during flare-ups. Omega-3 fatty acids reduce inflammation, fight bone loss, and alleviate symptoms of arthritis while preserving cartilage during arthrosis. The quality is excellent, the capsules are small, and the taste is pleasant with no unpleasant odour.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.1
USERS' SCORE
Good
Based on 5 Reviews
8.5
9.5
We explored the potential benefits of eicosapentaenoic acid (EPA), an essential fatty acid, in treating chronic fatigue syndrome (CFS). A female patient with a six-year history of persistent CFS symptoms participated in the study, receiving a daily supplement rich in EPA.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
9
Improved energy levels
Most Useful Review
34 people found this helpful
The effect is clear. Since I began taking Omega and Vitamin D while breastfeeding my 2-month-old daughter, my fatigue and sleepiness have significantly lessened. I feel lively and no longer struggle to stay awake during the day. My hair remains healthy, and I’ve had no acne issues, which I was concerned about. I will continue taking these supplements as they truly boost my wellbeing.
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 39 Researches
7.2
USERS' SCORE
Good
Based on 10 Reviews
8.5
9
Vitamin D3 improves depressive symptoms
We conducted a double-blind randomized clinical trial to explore the effects of vitamin D3 supplementation on depression. Our study involved 56 adults with mild to moderate depression, who were assigned to either a vitamin D group or a placebo group. Over the course of eight weeks, the vitamin D group received a high dose of 50,000 IU cholecalciferol every two weeks, while the control group received a placebo.
After the treatment period, we observed that the participants who received the vitamin D3 experienced a significant reduction in depression severity, as measured by the Beck Depression Inventory-II. Interestingly, this improvement in mood occurred independently of any changes in inflammatory biomarkers like IL-1β, IL-6, and hs-CRP, which we also assessed during the study.
This indicates that while vitamin D supplementation may positively impact depressive symptoms, its effects are not directly linked to the inflammatory markers we evaluated. Our findings suggest that vitamin D3 could be a helpful addition to depression treatment strategies, particularly in individuals with low vitamin D levels.
After the treatment period, we observed that the participants who received the vitamin D3 experienced a significant reduction in depression severity, as measured by the Beck Depression Inventory-II. Interestingly, this improvement in mood occurred independently of any changes in inflammatory biomarkers like IL-1β, IL-6, and hs-CRP, which we also assessed during the study.
This indicates that while vitamin D supplementation may positively impact depressive symptoms, its effects are not directly linked to the inflammatory markers we evaluated. Our findings suggest that vitamin D3 could be a helpful addition to depression treatment strategies, particularly in individuals with low vitamin D levels.
9
Depression prevention
Most Useful Review
46 people found this helpful
Excellent prenatal vitamins! Omega-3 plays a crucial role in pregnancy, helping to reduce the risk of late toxicity and depression. Nordic Naturals is entirely safe, with independent testing confirming high safety standards. Their production process eliminates heavy metals and dioxins, ensuring quality. The capsules have a pleasant taste and don't cause belching, which is common with many fish oils.
Insomnia details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.4
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
Vitamin D3 improves adolescent insomnia
We studied how high-dose vitamin D3 supplementation might affect insomnia in adolescent girls. Over nine weeks, 940 participants received a weekly dose of 50,000 IU of vitamin D3 while we tracked changes in their sleep patterns.
Interestingly, we observed a notable reduction in insomnia rates after the treatment. The number of girls reporting insomnia dropped from 15.0% to 11.3%, indicating that this vitamin can potentially improve sleep quality.
We also noticed a slight decrease in daytime sleepiness, with cases falling from 15.6% to 14.7%. Furthermore, those experiencing both insomnia and sleepiness saw a decline from 8.0% to 6.1%.
These findings suggest that high-dose vitamin D can play a significant role in alleviating sleep issues among adolescent girls. However, further studies are needed to see if these effects are consistent across diverse age and gender groups.
Interestingly, we observed a notable reduction in insomnia rates after the treatment. The number of girls reporting insomnia dropped from 15.0% to 11.3%, indicating that this vitamin can potentially improve sleep quality.
We also noticed a slight decrease in daytime sleepiness, with cases falling from 15.6% to 14.7%. Furthermore, those experiencing both insomnia and sleepiness saw a decline from 8.0% to 6.1%.
These findings suggest that high-dose vitamin D can play a significant role in alleviating sleep issues among adolescent girls. However, further studies are needed to see if these effects are consistent across diverse age and gender groups.
9
Improved sleep quality
Most Useful Review
Omega for pregnant women stabilises insomnia and alleviates stress. The natural ingredients also boost brain function and enhance sleep quality, particularly through GABA which promotes deeper rest. The dosage is optimal too.
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.5
9
No rash
Most Useful Review
3 people found this helpful
They had been searching for an omega for quite some time. She was on GV, then transitioned to these, worried that the baby might develop a rash. Thankfully, there is no rash, and we are delighted! :)))
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7
USERS' SCORE
Good
Based on 4 Reviews
8.4
9
We focused our research on the potential benefits of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, for individuals suffering from acne. Over a period of 16 weeks, we encouraged 60 patients to follow a Mediterranean diet while taking algae-derived EPA and docosahexaenoic acid (DHA) supplements. Our goal was to see if increasing their omega-3 levels could improve acne symptoms.
At the start of the study, an impressive 98.3% of the participants were found to have low levels of EPA/DHA. By the end of the study, we observed a significant increase in their omega-3 levels from an average of 4.9% to 8.3%. This boost correlated with noticeable improvements in both inflammatory and non-inflammatory acne lesions.
Interestingly, we noted that while individual perceptions of appearance varied—some reporting no improvement—overall quality of life for the participants enhanced significantly, particularly in those with papulopustular acne. Alongside dietary changes, participants reduced their intake of cow’s milk and dairy products, and we did not encounter any negative side effects from the intervention.
Ultimately, our findings suggest that boosting omega-3 fatty acids, particularly EPA, through diet and supplementation can effectively help manage acne severity in patients.
At the start of the study, an impressive 98.3% of the participants were found to have low levels of EPA/DHA. By the end of the study, we observed a significant increase in their omega-3 levels from an average of 4.9% to 8.3%. This boost correlated with noticeable improvements in both inflammatory and non-inflammatory acne lesions.
Interestingly, we noted that while individual perceptions of appearance varied—some reporting no improvement—overall quality of life for the participants enhanced significantly, particularly in those with papulopustular acne. Alongside dietary changes, participants reduced their intake of cow’s milk and dairy products, and we did not encounter any negative side effects from the intervention.
Ultimately, our findings suggest that boosting omega-3 fatty acids, particularly EPA, through diet and supplementation can effectively help manage acne severity in patients.
9
No acne issues
Most Useful Review
I tried elevit and femibion prenatals and noticed no nausea from these capsules, less hair loss, no acne, and softer skin, even in winter. My skin feels soft and moisturised.
Back Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
We sought to understand the role of vitamin D3 supplementation in alleviating chronic low back pain (CLBP). In a single-arm, open-label study at a tertiary care hospital, we worked with 68 patients suffering from CLBP for at least three months, each demonstrating a significant pain level on a visual scale alongside low vitamin D levels.
Participants received 60,000 IU of vitamin D3 weekly for eight weeks. We tracked pain intensity and functional disability at various stages: at the outset, and then at two, three, and six months post-supplementation. Notably, we witnessed a remarkable increase in vitamin D levels from an average of 12.8 ng/mL to 36.07 ng/mL in those eight weeks, with 66% of participants achieving normal vitamin D levels.
The benefits didn’t stop there. Patients reported a significant drop in their pain scores at all follow-up periods, improving from 81 to 36 on the scale. Functional ability also saw enhancement over time, proving the positive influence of vitamin D3 on both pain and everyday activities.
Overall, our findings suggest that vitamin D3 supplementation can be an effective avenue for improving pain intensity and functionality in individuals with low back pain, warranting further investigation through controlled clinical trials.
Participants received 60,000 IU of vitamin D3 weekly for eight weeks. We tracked pain intensity and functional disability at various stages: at the outset, and then at two, three, and six months post-supplementation. Notably, we witnessed a remarkable increase in vitamin D levels from an average of 12.8 ng/mL to 36.07 ng/mL in those eight weeks, with 66% of participants achieving normal vitamin D levels.
The benefits didn’t stop there. Patients reported a significant drop in their pain scores at all follow-up periods, improving from 81 to 36 on the scale. Functional ability also saw enhancement over time, proving the positive influence of vitamin D3 on both pain and everyday activities.
Overall, our findings suggest that vitamin D3 supplementation can be an effective avenue for improving pain intensity and functionality in individuals with low back pain, warranting further investigation through controlled clinical trials.
9
Reduced back pain
Most Useful Review
7 people found this helpful
I ordered omega after reading positive reviews. I didn’t expect such a result. My back pain eased, and the discomfort in my lower abdomen disappeared. After taking omega, there was no more tone on the second ultrasound. Omega also supports the development of the baby’s brain and promotes skin elasticity. I intend to continue taking omega throughout my pregnancy and beyond.
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 28 Researches
7.1
USERS' SCORE
Good
Based on 4 Reviews
8.4
8
We explored the connection between vitamin D levels and coronary thrombus load in patients who experienced ST-elevation myocardial infarction (STEMI). The study included 77 patients where we measured serum vitamin D levels, thrombus degree, and other relevant factors.
Our findings revealed that a concerning 79.22% of participants showed vitamin D deficiency, with those having milder thrombus loads possessing significantly higher vitamin D levels compared to those with severe thrombus loads. Moreover, as we assessed the severity of coronary artery condition, we noted that patients with higher thrombus burden also had markedly greater scores of atherosclerosis.
Importantly, we found clear negative correlations between vitamin D levels and measures of thrombus burden. Lower vitamin D levels aligned with higher TIMI frame counts—meaning more extensive vascular obstruction—suggesting that vitamin D might play a role in blood clot formation.
Overall, we determined that low 25(OH)D3 levels could be an independent predictor of high coronary artery thrombus load in STEMI patients. These findings highlight the potential significance of monitoring and perhaps addressing vitamin D levels in this vulnerable group.
Our findings revealed that a concerning 79.22% of participants showed vitamin D deficiency, with those having milder thrombus loads possessing significantly higher vitamin D levels compared to those with severe thrombus loads. Moreover, as we assessed the severity of coronary artery condition, we noted that patients with higher thrombus burden also had markedly greater scores of atherosclerosis.
Importantly, we found clear negative correlations between vitamin D levels and measures of thrombus burden. Lower vitamin D levels aligned with higher TIMI frame counts—meaning more extensive vascular obstruction—suggesting that vitamin D might play a role in blood clot formation.
Overall, we determined that low 25(OH)D3 levels could be an independent predictor of high coronary artery thrombus load in STEMI patients. These findings highlight the potential significance of monitoring and perhaps addressing vitamin D levels in this vulnerable group.
9
Maintains blood quality
Most Useful Review
13 people found this helpful
All tests are perfect. I started taking it in the first trimester of pregnancy, and I’m now 27 weeks along. I bought 2-3 cans and continue taking it. I experienced some issues like belching but no nausea. The small capsules are easy to swallow. It's essential to store them in the fridge, as heat can make them smell like fish. Omega is known to help maintain normal blood quality, preventing blood clots. Monthly tests show my platelets and erythrocytes are normal. I highly recommend it!
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.4
9
Relieved bone pain
Most Useful Review
7 people found this helpful
After reading positive reviews, I ordered the omega supplement during my pregnancy. I didn’t expect much, but it relieved my lower abdomen pain and reduced the tonus by my second ultrasound. Omega also promotes brain development in my baby and improves skin tightness. I'm pleased that my pain is gone and I will continue taking it throughout my pregnancy.
Constipation details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 8 Reviews
8.4
7
We explored the effects of probiotic supplementation combined with vitamin D3 on constipation and motor symptoms in individuals with Parkinson's disease. This study focused on a group of patients who had chronic constipation and used a specific probiotic formula.
Over the course of three months, we evaluated 32 patients to see if the supplementation made a difference in their digestive health and overall symptoms. We carefully monitored factors like bowel habits and employed various assessments to track the subjects' progress.
While our findings indicated some benefits from the probiotic intervention, the specific impact of vitamin D3 alone on constipation remains unclear due to the combination with probiotics in our approach. Therefore, we cannot draw definitive conclusions about the effectiveness of vitamin D3 by itself in alleviating constipation. Our research does suggest that the gut microbiome plays a role in managing symptoms associated with Parkinson's disease, emphasizing the importance of ongoing investigations in this field.
Over the course of three months, we evaluated 32 patients to see if the supplementation made a difference in their digestive health and overall symptoms. We carefully monitored factors like bowel habits and employed various assessments to track the subjects' progress.
While our findings indicated some benefits from the probiotic intervention, the specific impact of vitamin D3 alone on constipation remains unclear due to the combination with probiotics in our approach. Therefore, we cannot draw definitive conclusions about the effectiveness of vitamin D3 by itself in alleviating constipation. Our research does suggest that the gut microbiome plays a role in managing symptoms associated with Parkinson's disease, emphasizing the importance of ongoing investigations in this field.
9
Alleviates constipation
Most Useful Review
5 people found this helpful
The Omega-3 Prenatal DHA capsules are small and easy to swallow, with no flavours or additives. Each capsule contains 830 mg of Omega-3 and 400 IU of Vitamin D3. Along with DHA, it includes EPA, which is beneficial during pregnancy. I found it effective during my second trimester; it alleviated constipation and had no unpleasant aftertaste.
High Cholesterol details
SCIENTIFIC SCORE
Possibly Effective
Based on 34 Researches
7.7
USERS' SCORE
Good
Based on 4 Reviews
8.4
9
We investigated how vitamin D3 supplements impact cholesterol levels in pediatric patients suffering from obesity. The study involved 723 children over two years, with 283 receiving vitamin D3 and 440 on a placebo.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
9
High cholesterol relief
Most Useful Review
15 people found this helpful
I found this product to be of very high quality. Living in Moscow, I struggled to find an omega supplement for pregnant women to address my high cholesterol as prescribed by my endocrinologist. This omega has a pleasant smell of fish. It doesn’t disgust me and feels just like taking a regular vitamin. I recommend it without hesitation!
Nausea details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 20 Reviews
8.4
7
We conducted a retrospective cohort study to investigate the relationship between nausea and vomiting in pregnancy (NVP) and dysmenorrhea measured by a verbal rating scale. Our research included 443 pregnant women, divided into those experiencing NVP and a control group.
From our findings, we noticed a clear association between moderate to severe dysmenorrhea and a heightened risk of NVP, especially during the first trimester. This suggests that those with painful menstrual symptoms may face an increased likelihood of nausea and vomiting as part of their pregnancy experience.
Importantly, we also examined the impact of periconceptional supplementation with docosahexaenoic acid (DHA). Our results indicated that taking DHA could potentially lower the risk of NVP, offering a glimmer of hope for managing nausea during pregnancy. This suggests that combining DHA with standard prenatal care might be beneficial for those who struggle with these symptoms.
Overall, our study sheds light on the intricate connections between menstrual pain and pregnancy-related nausea, emphasizing the potential protective role of DHA in improving women's health during this time.
From our findings, we noticed a clear association between moderate to severe dysmenorrhea and a heightened risk of NVP, especially during the first trimester. This suggests that those with painful menstrual symptoms may face an increased likelihood of nausea and vomiting as part of their pregnancy experience.
Importantly, we also examined the impact of periconceptional supplementation with docosahexaenoic acid (DHA). Our results indicated that taking DHA could potentially lower the risk of NVP, offering a glimmer of hope for managing nausea during pregnancy. This suggests that combining DHA with standard prenatal care might be beneficial for those who struggle with these symptoms.
Overall, our study sheds light on the intricate connections between menstrual pain and pregnancy-related nausea, emphasizing the potential protective role of DHA in improving women's health during this time.
9
No nausea experience
Most Useful Review
13 people found this helpful
All tests are perfect. I began taking it in my first trimester and continue at 27 weeks. It helped with my toxicosis, causing belching but no nausea. The capsules are small and easy to swallow. Just ensure they are stored in the fridge, as heat causes a fishy smell. Omega has helped maintain my blood quality. I have monthly tests, and my platelets and erythrocytes are normal. I recommend it for health.
Bloating details
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Good
Based on 7 Reviews
8.3
9
We explored the effectiveness of OsteoCalVitFort, a supplement combining 500 mg of calcium and 400 IU of vitamin D3, focusing specifically on its impact on bloating. The study involved 186 participants aged 18 to 65 years, who took two tablets daily—one after breakfast and one after dinner.
Through follow-up phone calls, we gathered information about any side effects and the overall satisfaction with the supplement. Notably, we observed a significant reduction in bloating, with the rate decreasing from 12.5% before taking the supplement to just 0.6% after. This impressive drop highlights the potential benefits of vitamin D3 in alleviating bloating discomfort.
Overall, the findings suggest that OsteoCalVitFort is not only effective but also well-received by users, with 94% reporting satisfaction with their experience. Importantly, we noted that no significant adverse effects were reported, setting OsteoCalVitFort apart from other supplements often linked with gastrointestinal issues.
Through follow-up phone calls, we gathered information about any side effects and the overall satisfaction with the supplement. Notably, we observed a significant reduction in bloating, with the rate decreasing from 12.5% before taking the supplement to just 0.6% after. This impressive drop highlights the potential benefits of vitamin D3 in alleviating bloating discomfort.
Overall, the findings suggest that OsteoCalVitFort is not only effective but also well-received by users, with 94% reporting satisfaction with their experience. Importantly, we noted that no significant adverse effects were reported, setting OsteoCalVitFort apart from other supplements often linked with gastrointestinal issues.
9
No bloating experienced
Most Useful Review
During pregnancy, maintaining health is vital, and this product's excellent fat and acid content is necessary for the body. I liked it very much; there is no bloating or heaviness after taking it.
Common Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 6 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.3
8
Vitamin D3 improves cold symptoms
We conducted a thorough investigation into how 25-hydroxyvitamin D3, commonly referred to as vitamin D3, impacts upper respiratory tract infections (URTIs), particularly the common cold. This study was carried out as a randomized, double-blind, placebo-controlled trial, engaging 428 participants, all aged between 45 and 74, across three clinics in Japan.
Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.
Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.
Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
9
Improved common cold
Most Useful Review
1 people found this helpful
I have been taking omega-3 since the first trimester on my gynecologist's advice. I researched thoroughly and chose this expensive product due to its reliable certification and good dosage. It economically lasts three months as I take one capsule daily. The fish oil is sourced from wild fish, minimising heavy metal risks. There’s no unpleasant aftertaste or fishy belching, and it has notably improved my dry skin. It’s essential for brain and heart development, and I recommend it.
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 36 Researches
7.1
USERS' SCORE
Good
Based on 7 Reviews
8.3
9
We explored the impact of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on heart disease through a significant study known as the VITAL trial. This study involved nearly 26,000 older adults in the U.S. and aimed to determine the effects of daily EPA supplementation on cardiovascular events over an average follow-up of 5.3 years.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
9
Vital for development
Most Useful Review
20 people found this helpful
This is the only DHA I recommend to my patients. It's clean and safe, essential in the third trimester for the baby's brain, nervous system, and eyes. If you want a clever baby, buy this product. The small capsules are easy to swallow and cause minimal reflux when taken with food.
Leg Cramps details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.3
9
Legs pain relief
Most Useful Review
Good Omega! My legs no longer hurt, and the episodes of leg cramps have stopped. During my previous pregnancy, I was very worn out, but this Omega has made everything fine.
Osteoporosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 40 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.3
7
We examined the relationship between docosahexaenoic acid (DHA) and osteoporosis using a method called 2-sample Mendelian randomization. This approach allowed us to investigate if higher levels of DHA could be a risk factor for osteoporosis.
Our findings revealed a causal tie: increased blood levels of DHA were indeed linked to a higher risk of developing osteoporosis. Specifically, for each standard deviation increase in DHA levels, the risk for osteoporosis rose by nearly 10%. We found this connection to be statistically significant, with a P-value of 0.033.
However, it's important to point out that the genetic correlation between DHA and osteoporosis was weak, suggesting that this relationship might not be heavily influenced by our genes. While these results indicate that DHA levels are a risk factor for osteoporosis, the underlying mechanisms are still unclear, highlighting the need for further research in this area.
Our findings revealed a causal tie: increased blood levels of DHA were indeed linked to a higher risk of developing osteoporosis. Specifically, for each standard deviation increase in DHA levels, the risk for osteoporosis rose by nearly 10%. We found this connection to be statistically significant, with a P-value of 0.033.
However, it's important to point out that the genetic correlation between DHA and osteoporosis was weak, suggesting that this relationship might not be heavily influenced by our genes. While these results indicate that DHA levels are a risk factor for osteoporosis, the underlying mechanisms are still unclear, highlighting the need for further research in this area.
7.5
Supports osteoporosis treatment
Most Useful Review
This omega is fantastic for pregnant women. Omega-3s help prevent osteoporosis, relieve inflammation, and combat bone loss. Additionally, they ease joint pain and mitigate symptoms of rheumatoid arthritis.
Anemia details
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.1
USERS' SCORE
Good
Based on 2 Reviews
8.1
We conducted a study to see how vitamin D3 might help improve iron levels in women of childbearing age who had marginally low iron stores. Our approach involved a carefully designed 8-week randomized controlled trial, where 120 women aged between 19 and 40 were divided into two groups. One group received fruit juice fortified with 4000 IU of vitamin D3 daily, while the other had a placebo juice.
Throughout the study, we collected blood samples and monitored various health indicators every four weeks. We aimed to find out if the vitamin D3 supplementation could positively influence the iron status of the participants compared to the placebo.
Given the promising role of vitamin D in enhancing iron absorption, we hoped to uncover new insights into dietary strategies for managing iron deficiency. By observing the interaction over time between vitamin D levels and iron status, we aimed to provide valuable information on whether this fortification could serve as a practical alternative to traditional iron supplements.
As we gathered data, we explored the potential of vitamin D3 beyond its usual role, assessing if it could indeed help improve the anemia indicators in our target group.
Throughout the study, we collected blood samples and monitored various health indicators every four weeks. We aimed to find out if the vitamin D3 supplementation could positively influence the iron status of the participants compared to the placebo.
Given the promising role of vitamin D in enhancing iron absorption, we hoped to uncover new insights into dietary strategies for managing iron deficiency. By observing the interaction over time between vitamin D levels and iron status, we aimed to provide valuable information on whether this fortification could serve as a practical alternative to traditional iron supplements.
As we gathered data, we explored the potential of vitamin D3 beyond its usual role, assessing if it could indeed help improve the anemia indicators in our target group.
9
Prevented anaemia risks
Most Useful Review
5 people found this helpful
During my first pregnancy, I neglected vitamins, thinking they were unnecessary. Now, I realise that taking vitamins is crucial for my health and to avoid complications like anaemia after childbirth. I strongly recommend pregnant women to take at least fish oil and iron supplements for their benefit.
Cardiovascular Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.2
USERS' SCORE
Good
Based on 8 Reviews
8.1
9
We explored the impact of eicosapentaenoic acid (EPA), a nutrient known for its heart benefits, on diabetic cardiomyopathy (DC), a condition leading to heart failure. Our study focused on diabetic mice and revealed that EPA plays a protective role against DC, particularly by reducing harmful M1-polarized macrophages in the heart.
In our experiments, we found that EPA not only reduces cardiomyocyte injury caused by M1-polarized macrophages but also encourages a shift in macrophages' behavior from M1 to a protective Mox state—not M2. This shift is crucial because Mox macrophages help mitigate the damage inflicted by their M1 counterparts.
We identified heme oxygenase 1 (HO-1) as a key player in maintaining the Mox phenotype. EPA promotes HO-1, which helps curb macrophage M1 polarization and the resulting cardiomyocyte injury. Interestingly, our findings also showed that EPA fosters this protective Mox polarization in monocyte-derived macrophages from diabetic patients, suggesting a broader application for this treatment strategy.
Overall, our study highlights the potential of EPA as a novel approach to combat diabetic cardiomyopathy, emphasizing the importance of macrophage Mox polarization in maintaining heart health in diabetes.
In our experiments, we found that EPA not only reduces cardiomyocyte injury caused by M1-polarized macrophages but also encourages a shift in macrophages' behavior from M1 to a protective Mox state—not M2. This shift is crucial because Mox macrophages help mitigate the damage inflicted by their M1 counterparts.
We identified heme oxygenase 1 (HO-1) as a key player in maintaining the Mox phenotype. EPA promotes HO-1, which helps curb macrophage M1 polarization and the resulting cardiomyocyte injury. Interestingly, our findings also showed that EPA fosters this protective Mox polarization in monocyte-derived macrophages from diabetic patients, suggesting a broader application for this treatment strategy.
Overall, our study highlights the potential of EPA as a novel approach to combat diabetic cardiomyopathy, emphasizing the importance of macrophage Mox polarization in maintaining heart health in diabetes.
7.5
Vital nutrient effect
Most Useful Review
20 people found this helpful
The only DHA I prescribe for my patients, it's safe, clean, and crucial in the third trimester for fetal brain and nervous system development. For a smart baby that achieves milestones, purchase this product. Capsules are small and easy to swallow, with minimal reflux. Best taken with food for optimal absorption.
Pelvic Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.1
9
Alleviated abdominal pain
Most Useful Review
7 people found this helpful
Essential supplement during pregnancy! After ordering omega based on positive reviews, I found that my previous abdominal pain disappeared, and the tonus reduced significantly. I’m also aware that omega supports the baby's brain development and positively impacts the fetus, making me pleased that the feeling of tightness in my skin has gone. I will continue to take omega throughout my pregnancy.
Reflux details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 8 Reviews
8.1
9
We aimed to understand whether vitamin D3 can have a beneficial effect on reflux esophagitis (RE), a condition caused by stomach acid irritating the esophagus. To explore this, we conducted experiments on seventy male Sprague-Dawley rats, dividing them into groups to study both acute and chronic forms of RE. We treated some of these rats with varying doses of vitamin D3, while others did not receive this treatment, allowing us to compare differences in inflammation levels.
The results showed that the levels of important pro-inflammatory proteins—IL-1β, IL-6, and IL-8—were significantly elevated in the rats suffering from RE. However, when we treated the rats with vitamin D3, we observed a notable reduction in these inflammatory markers, but only in the acute RE group. Unfortunately, similar benefits were not evident in the chronic RE group, and vitamin D3 did not improve the overall condition of the esophagus on a structural level.
Interestingly, our histopathological examinations revealed varying degrees of esophageal damage, regardless of vitamin D3 treatment. While elevated serum calcium levels were noted following vitamin D3 treatment, this did not translate into improvements in chronic RE cases. Overall, our findings point to a potential protective role of vitamin D3 in early-stage reflux esophagitis, suggesting that it might help manage inflammation at the beginning of this condition.
The results showed that the levels of important pro-inflammatory proteins—IL-1β, IL-6, and IL-8—were significantly elevated in the rats suffering from RE. However, when we treated the rats with vitamin D3, we observed a notable reduction in these inflammatory markers, but only in the acute RE group. Unfortunately, similar benefits were not evident in the chronic RE group, and vitamin D3 did not improve the overall condition of the esophagus on a structural level.
Interestingly, our histopathological examinations revealed varying degrees of esophageal damage, regardless of vitamin D3 treatment. While elevated serum calcium levels were noted following vitamin D3 treatment, this did not translate into improvements in chronic RE cases. Overall, our findings point to a potential protective role of vitamin D3 in early-stage reflux esophagitis, suggesting that it might help manage inflammation at the beginning of this condition.
9
No reflux observed
Most Useful Review
20 people found this helpful
This is the only DHA I prescribe to my patients. It's clean, regulated, and vital for foetal brain and eye development in the third trimester. If you want a clever baby who meets milestones easily, buy this product. The small capsules are easy to swallow and cause minimal reflux. It's best taken with food for optimal absorption.
Heart Attack details
SCIENTIFIC SCORE
Possibly Effective
Based on 39 Researches
7.8
USERS' SCORE
Good
Based on 6 Reviews
8
9
We examined the impact of calcitriol, the active form of vitamin D, on heart attack recovery using a mouse model of myocardial infarction (MI). In our study, we treated mice that had suffered a MI with calcitriol and observed promising results.
Our findings revealed that calcitriol helped reverse negative effects on heart function and reduced cardiac remodeling after a heart attack. It also targeted the inflammatory response typically associated with MI, improving the survival of heart muscle cells and promoting their regeneration.
We discovered that calcitriol works by enhancing the activity of the Vitamin D receptor (VDR). This process not only interferes with inflammatory signals but also leads to positive changes at the genetic level, further supporting heart health after an MI. Overall, our study provides strong evidence of calcitriol's cardioprotective properties, making it a potential treatment avenue for better outcomes following a heart attack.
Our findings revealed that calcitriol helped reverse negative effects on heart function and reduced cardiac remodeling after a heart attack. It also targeted the inflammatory response typically associated with MI, improving the survival of heart muscle cells and promoting their regeneration.
We discovered that calcitriol works by enhancing the activity of the Vitamin D receptor (VDR). This process not only interferes with inflammatory signals but also leads to positive changes at the genetic level, further supporting heart health after an MI. Overall, our study provides strong evidence of calcitriol's cardioprotective properties, making it a potential treatment avenue for better outcomes following a heart attack.
9
Heart disease prevention
Most Useful Review
Omega-3 fatty acids are effective against cardiovascular disease, cleaning blood vessels and lowering heart attack risk. The quality is excellent, and I appreciate the natural ingredients and reasonable price. My overall health has improved significantly.
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 41 Researches
7.7
USERS' SCORE
Moderately Good
Based on 6 Reviews
7.5
9
We explored how Vitamin D3 impacts autoimmune thyroiditis, a specific autoimmune disorder. In this study, researchers established a mouse model of experimental autoimmune thyroiditis (EAT) to see how Vitamin D3 could influence this condition. After eight weeks of treatment, they assessed thyroid health and immune response through various methods, including staining tissues and measuring hormone levels.
Our observations revealed that administering Vitamin D3 helped reduce damage to the thyroid and decreased the presence of inflammatory cells within the thyroid. This treatment also led to lower levels of thyroid hormones and autoimmune antibodies in the blood, highlighting its positive effect on thyroid function. Additionally, Vitamin D3 appeared to promote the regulatory T cell (Treg) subset while decreasing the levels of Th17 cells, which are often involved in autoimmune processes.
Mechanistically, the study found that Vitamin D3 triggered specific pathways that influence Treg cell activity and survival. Notably, it activated a signaling pathway involving YAP and JAK/STAT, which are crucial for immune cell regulation. These findings suggest that Vitamin D3 could play a significant role in balancing immune responses in autoimmune thyroiditis, making it a promising candidate for further research and potential treatment strategies.
Our observations revealed that administering Vitamin D3 helped reduce damage to the thyroid and decreased the presence of inflammatory cells within the thyroid. This treatment also led to lower levels of thyroid hormones and autoimmune antibodies in the blood, highlighting its positive effect on thyroid function. Additionally, Vitamin D3 appeared to promote the regulatory T cell (Treg) subset while decreasing the levels of Th17 cells, which are often involved in autoimmune processes.
Mechanistically, the study found that Vitamin D3 triggered specific pathways that influence Treg cell activity and survival. Notably, it activated a signaling pathway involving YAP and JAK/STAT, which are crucial for immune cell regulation. These findings suggest that Vitamin D3 could play a significant role in balancing immune responses in autoimmune thyroiditis, making it a promising candidate for further research and potential treatment strategies.
9
Positive impact
Most Useful Review
15 people found this helpful
Good way to promote brain and eye health! I took two capsules daily during pregnancy and breastfeeding for adequate DHA for my baby. This supplement is recommended to decrease issues like allergies, eczema, and attention deficit disorders in children. I highly recommend this product.
Dizziness details
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.9
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.5
9
We sought to understand the impact of severe vitamin D deficiency on benign paroxysmal positional vertigo (BPPV), a common cause of dizziness. Previous studies showed a connection between low vitamin D levels and both the onset and recurrence of BPPV, but none had conclusively demonstrated that addressing this deficiency could lessen the recurrence of symptoms.
To examine this further, we included patients diagnosed with unilateral, idiopathic posterior canal BPPV and severe vitamin D deficiency, indicated by levels of 25-hydroxyvitamin D3 at or below 10 ng/ml. After thorough evaluations including hearing tests and balance assessments, we prescribed vitamin D therapy to our participants.
Over the following months, we monitored the changes in their vitamin D levels and followed up with them for 18 months to observe any recurrence of dizziness. Our findings revealed that patients who showed an improvement in their vitamin D levels experienced a significant reduction in the recurrence of BPPV symptoms.
This suggests that by addressing vitamin D deficiency, we can potentially offer a more effective approach to managing BPPV—lessening those troublesome dizzy spells that can really impact quality of life.
To examine this further, we included patients diagnosed with unilateral, idiopathic posterior canal BPPV and severe vitamin D deficiency, indicated by levels of 25-hydroxyvitamin D3 at or below 10 ng/ml. After thorough evaluations including hearing tests and balance assessments, we prescribed vitamin D therapy to our participants.
Over the following months, we monitored the changes in their vitamin D levels and followed up with them for 18 months to observe any recurrence of dizziness. Our findings revealed that patients who showed an improvement in their vitamin D levels experienced a significant reduction in the recurrence of BPPV symptoms.
This suggests that by addressing vitamin D deficiency, we can potentially offer a more effective approach to managing BPPV—lessening those troublesome dizzy spells that can really impact quality of life.
9
Reduces dizziness
Most Useful Review
3 people found this helpful
I took this from the sixth month of pregnancy while breastfeeding. I observed my baby gained weight well and was healthy, which is different from my previous children. This is my experience, and I believe it helped with dizziness.
