Nordic Naturals Postnatal Omega-3

We conducted a double-blind randomized clinical trial to explore the effects of vitamin D3 supplementation on depression. Our study involved 56 adults with mild to moderate depression, who were assigned to either a vitamin D group or a placebo group. Over the course of eight weeks, the vitamin D group received a high dose of 50,000 IU cholecalciferol every two weeks, while the control group received a placebo.

After the treatment period, we observed that the participants who received the vitamin D3 experienced a significant reduction in depression severity, as measured by the Beck Depression Inventory-II. Interestingly, this improvement in mood occurred independently of any changes in inflammatory biomarkers like IL-1β, IL-6, and hs-CRP, which we also assessed during the study.

This indicates that while vitamin D supplementation may positively impact depressive symptoms, its effects are not directly linked to the inflammatory markers we evaluated. Our findings suggest that vitamin D3 could be a helpful addition to depression treatment strategies, particularly in individuals with low vitamin D levels.

Mood improvement

Most Useful Review

I have been taking it for twenty days now. My hair has improved, and my nervousness and lack of focus have eased. Symptoms of depression, anxiety, distraction, forgetfulness, and stammering have diminished by almost 80%. I hope this helps you.

High Cholesterol

SCIENTIFIC SCORE

Possibly Effective

Based on 40 Researches

Vitamin D3 lowers cholesterol levels

Vitamin D Supplementation Reduces Hyperlipidemia and Improves Bone Mass in Pediatric Obesity.

Most Relevant Research

We investigated how vitamin D3 supplements impact cholesterol levels in pediatric patients suffering from obesity. The study involved 723 children over two years, with 283 receiving vitamin D3 and 440 on a placebo.

After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.

Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.

Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.

9.5

Improved cholesterol levels

Most Useful Review

Omega-3 acids effectively "cleanse" blood vessel walls from excess "bad" cholesterol, reducing the risk of high cholesterol and atherosclerosis. They enhance blood viscosity, normalise blood pressure, and bolster "good" cholesterol (HDL) levels. Moreover, these acids strengthen blood vessel walls and improve their elasticity. They contribute to the synthesis of important substances in the body, particularly influencing sleep. I found the quality and taste to be excellent, and I highly recommend this product.

Autoimmune Disorder

SCIENTIFIC SCORE

Possibly Effective

Based on 47 Researches

Vitamin D3 modulates autoimmune response

Vitamin D3 attenuates autoimmune thyroiditis by regulating Th17/Treg cell differentiation via YAP/JAK1/STAT1 axis.

Most Relevant Research

We explored how Vitamin D3 impacts autoimmune thyroiditis, a specific autoimmune disorder. In this study, researchers established a mouse model of experimental autoimmune thyroiditis (EAT) to see how Vitamin D3 could influence this condition. After eight weeks of treatment, they assessed thyroid health and immune response through various methods, including staining tissues and measuring hormone levels.

Our observations revealed that administering Vitamin D3 helped reduce damage to the thyroid and decreased the presence of inflammatory cells within the thyroid. This treatment also led to lower levels of thyroid hormones and autoimmune antibodies in the blood, highlighting its positive effect on thyroid function. Additionally, Vitamin D3 appeared to promote the regulatory T cell (Treg) subset while decreasing the levels of Th17 cells, which are often involved in autoimmune processes.

Mechanistically, the study found that Vitamin D3 triggered specific pathways that influence Treg cell activity and survival. Notably, it activated a signaling pathway involving YAP and JAK/STAT, which are crucial for immune cell regulation. These findings suggest that Vitamin D3 could play a significant role in balancing immune responses in autoimmune thyroiditis, making it a promising candidate for further research and potential treatment strategies.

8.8

Improved skin condition

Most Useful Review

After two years of breastfeeding, I decided to improve my health as I experienced hair loss and skin inflammation. Remembering the Nordic brand, I used their fish oil during pregnancy, which positively affected my skin and mood. This supplement has reduced inflammation on my chin, especially when combined with evening primrose oil. Nordic's products are worth the money; I've seen better results than with other brands.

Pelvic Pain

Effective pain relief

Most Useful Review

I purchased this for my daughter who gave birth six months ago and is breastfeeding. She is very pleased with the results! This excellent recovery complex alleviated her pelvic pain within a week of taking it, improved her general health, lifted her mood, and even enhanced her sleep quality. I highly recommend it to all women who have recently given birth!