' 
Supplement Facts
Serving Size: 31 g (About 1 Scoop)
Amount Per Serving
%DV
Calories
120
Total Fat
1.5 g
2%
Saturated Fat
1 g
5%
Cholesterol
60 mg
20%
Sodium
130 mg
6%
Total Carbohydrate
3 g
1%
Total Sugars
2 g
Protein
24 g
48%
Calcium
140 mg
10%
Potassium
150 mg
4%
The product is found useful for the following medical conditions
Back Pain
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 3 Reviews
8.7
9
Calcium aids in back pain relief
Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation.
Most Relevant Research
We explored the impact of calcium and vitamin D supplementation combined with sling core stabilization training on back pain in a 70-year-old female patient suffering from osteoporosis. The patient engaged in this form of exercise three times a week, focusing on strengthening the deep muscles of her spine.
After a year of dedicated training, not only did her back pain significantly improve, but a follow-up examination also indicated an increase in her bone mineral density. This suggests that the combined approach of exercise and supplementation might promote better bone health and potentially reduce pain.
However, it’s important to note that while we saw positive changes in this case, the specific contributions of calcium alone cannot be clearly identified due to the concurrent treatments involved. Therefore, we recognize that further studies are needed to isolate calcium's effects to conclusively determine its role in managing back pain effectively.
After a year of dedicated training, not only did her back pain significantly improve, but a follow-up examination also indicated an increase in her bone mineral density. This suggests that the combined approach of exercise and supplementation might promote better bone health and potentially reduce pain.
However, it’s important to note that while we saw positive changes in this case, the specific contributions of calcium alone cannot be clearly identified due to the concurrent treatments involved. Therefore, we recognize that further studies are needed to isolate calcium's effects to conclusively determine its role in managing back pain effectively.
9.5
Reduces back pain
Most Useful Review
This powder has been a game changer! Since I started using it, my back pain after gym sessions has drastically diminished. I can work out more frequently now without the agony I used to experience. I initially thought eating more meat would suffice, but this supplement truly provides the relief I need.
Autoimmune Disorder
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.5
USERS' SCORE
Good
Based on 1 Review
8.6
9
Targeted HS delivery alleviates RA
NaHS@Cy5@MS@SP nanoparticles improve rheumatoid arthritis by inactivating the Hedgehog signaling pathway through sustained and targeted release of HS into the synovium.
Most Relevant Research
We explored a new strategy to treat rheumatoid arthritis (RA) by using nanoparticles to deliver hydrogen sulfide (HS) directly to affected joints. Our research focused on how effectively these nanoparticles, called NaHS@Cy5@MS@SP, could target specific cells involved in inflammation and tissue damage in RA. By slowly releasing HS in the synovium, we aimed to combat the negative effects of inflammation caused by fibroblast-like synoviocytes (FLSs).
Throughout our investigations, we observed that the nanoparticles not only increased levels of HS but also boosted the activity of an enzyme linked to its production. This intervention showed promising results, as it significantly reduced inflammation and proliferation of FLSs in laboratory settings. In mice with arthritis, those treated with the nanoparticles experienced reduced joint swelling and less damage to their bones and cartilage compared to those receiving conventional HS treatment.
Additionally, we confirmed that the nanoparticles were effective in shutting down the Hedgehog signaling pathway, which is known for promoting excessive cellular growth and inflammation in RA. Our findings support the idea that delivering HS in a targeted manner can improve treatment outcomes, offering hope for more effective therapies for RA moving forward.
Throughout our investigations, we observed that the nanoparticles not only increased levels of HS but also boosted the activity of an enzyme linked to its production. This intervention showed promising results, as it significantly reduced inflammation and proliferation of FLSs in laboratory settings. In mice with arthritis, those treated with the nanoparticles experienced reduced joint swelling and less damage to their bones and cartilage compared to those receiving conventional HS treatment.
Additionally, we confirmed that the nanoparticles were effective in shutting down the Hedgehog signaling pathway, which is known for promoting excessive cellular growth and inflammation in RA. Our findings support the idea that delivering HS in a targeted manner can improve treatment outcomes, offering hope for more effective therapies for RA moving forward.
9.5
Effective treatment
Most Useful Review
I am absolutely delighted! This is not my first order; I have previously bought numerous domestic proteins, all of which were a complete waste of money. However, this American protein is by far the best I have tried. I noticed an instant effect from it. I am exceptionally pleased and have ordered more creatine from this company.
Bloating
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Good
Based on 1 Review
8.6
7
A2 milk's mixed impact on bloating
The Effect of A2 Milk on Gastrointestinal Symptoms in Comparison to A1/A2 Milk: A Single-center, Randomized, Double-blind, Cross-over Study.
Most Relevant Research
We aimed to understand how different types of milk affect bloating, particularly focusing on A2 milk versus regular A1/A2 milk. In this study, we conducted a randomized, double-blind, cross-over trial with 40 participants who reported experiencing gastrointestinal discomfort after consuming milk.
Over two weeks, each participant consumed either A2 milk or A1/A2 milk, separated by a two-week washout period. Using various assessments like symptom rating scales and digestive symptom questionnaires, we examined the effects on bloating and other gastrointestinal symptoms.
Our findings revealed that A2 milk did increase reports of bloating and loose stools compared to the A1/A2 type. However, participants also indicated experiencing less abdominal pain and urgency when consuming A2 milk. Interestingly, fecal calprotectin levels were less elevated after consuming A2 milk, particularly in males, suggesting that A2 milk may help alleviate some digestive discomfort.
Overall, while A2 milk was associated with less abdominal pain and urgency, some individuals did experience increased bloating. Despite this, the study didn't report any significant adverse effects, suggesting that A2 milk could be a viable option for those with mild digestive issues related to milk consumption.
Over two weeks, each participant consumed either A2 milk or A1/A2 milk, separated by a two-week washout period. Using various assessments like symptom rating scales and digestive symptom questionnaires, we examined the effects on bloating and other gastrointestinal symptoms.
Our findings revealed that A2 milk did increase reports of bloating and loose stools compared to the A1/A2 type. However, participants also indicated experiencing less abdominal pain and urgency when consuming A2 milk. Interestingly, fecal calprotectin levels were less elevated after consuming A2 milk, particularly in males, suggesting that A2 milk may help alleviate some digestive discomfort.
Overall, while A2 milk was associated with less abdominal pain and urgency, some individuals did experience increased bloating. Despite this, the study didn't report any significant adverse effects, suggesting that A2 milk could be a viable option for those with mild digestive issues related to milk consumption.
9.5
No gas problems
Most Useful Review
I'm so glad I bought this chocolate protein powder based on the reviews. I mix it with milk and peanut powder for a protein boost. It tastes great, and so far, I've experienced no bloating or gas. Initially, I tried one shake, but I've now moved up to two daily. I still have no issues with bloating or gas. It's a fantastic product.
Cold
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.6
9.5
Helps manage cravings
Most Useful Review
Fortunately, this product is excellent. I've used it as part of my fitness plan and again during pregnancy. It helps control my cravings, supports my blood sugar levels, and doesn't upset my stomach. I would highly recommend it for anyone managing their diet.
Diabetes
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Supports blood sugar
Most Useful Review
This product is excellent for my fitness nutrition plan, requiring daily protein shakes. Initially hesitant, I found it enjoyable (double rich chocolate) and dissolves well. With recent gestational diabetes, it effectively helps control my glucose levels, relieving cravings. After a dangerous blood sugar drop, it helped stabilize my levels with juice and protein. Highly recommend for managing gestational or type 2 diabetes.
Bone Pain
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 4 Reviews
8.5
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
Most Relevant Research
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
9.5
Effective pain relief
Most Useful Review
It does the job! Since starting at the gym last year, I endured days of bone pain afterwards. This powder (currently on my second container) significantly dulls the pain when taken after workouts. Thanks to this product, I can exercise much more frequently. I initially thought eating more meat would help, but this powder truly addresses my bone pain!
Breast Cancer
SCIENTIFIC SCORE
Moderately Effective
Based on 13 Researches
8.4
USERS' SCORE
Good
Based on 1 Review
8.4
9
Gracillin shows promise against cancer
Gracillin suppresses cancer progression through inducing Merlin/LATS protein-protein interaction and activating Hippo signaling pathway.
Most Relevant Research
We investigated the potential of gracillin, a natural saponin derived from herbs, as a treatment for breast cancer and other malignancies. In our research, gracillin demonstrated significant ability to slow down the growth of breast cancer cells, liver cancer cells, and glioblastoma cells. The experiments showed that gracillin effectively inhibited cell proliferation, migration, and invasion at concentrations around 1 μM.
This natural compound works by activating the Hippo signaling pathway in a unique way. We found that gracillin enhances the interaction between two proteins, Merlin and LATS, which is crucial for activating this pathway. Disrupting this interaction with a specific peptide negated gracillin's anticancer effects, highlighting its importance in our findings.
Additionally, we conducted tests on nude mice with breast cancer tumors. The administration of gracillin resulted in a noticeable reduction in tumor growth, correlating with the induced protein interactions and the activated Hippo signaling. Our results underscore the promise of gracillin as a potential therapeutic agent in cancer treatment, particularly through its novel approach to activating crucial signaling pathways.
This natural compound works by activating the Hippo signaling pathway in a unique way. We found that gracillin enhances the interaction between two proteins, Merlin and LATS, which is crucial for activating this pathway. Disrupting this interaction with a specific peptide negated gracillin's anticancer effects, highlighting its importance in our findings.
Additionally, we conducted tests on nude mice with breast cancer tumors. The administration of gracillin resulted in a noticeable reduction in tumor growth, correlating with the induced protein interactions and the activated Hippo signaling. Our results underscore the promise of gracillin as a potential therapeutic agent in cancer treatment, particularly through its novel approach to activating crucial signaling pathways.
7.5
Protein benefits highlight
Most Useful Review
#1 product on the market! I'm a Certified Master Trainer with over 20 years of experience, and I use Whey Protein Isolate daily. Specifically, I swear by Optimum Nutrition 100% Whey Gold Standard because it offers great protein concentration and minimal lactose. It's crucial for muscle and immune health, and it even helps reduce the risk of breast cancer in women. The taste is phenomenal, and it mixes well, ensuring I get the nutrition I need to stay fit and healthy.
Hives
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.3
9
Ligelizumab effectively treats CSU
From wheal to wellness: efficacy and safety of ligelizumab in chronic spontaneous urticaria: a systematic review and meta-analysis.
Most Relevant Research
We explored how ligelizumab, a humanized monoclonal antibody that targets IgE, can help those suffering from chronic spontaneous urticaria (CSU). This condition features persistent hives and itching lasting more than six weeks, often causing significant discomfort and distress.
To gain a clearer understanding, we reviewed various studies, focusing on randomized controlled trials comparing ligelizumab with a placebo. Our analysis included data from 2,581 patients and revealed that ligelizumab significantly improved symptoms. A crucial finding was that the 72 mg dose of ligelizumab effectively reduced itch severity and overall hives activity.
We observed that patients receiving this dosage experienced a marked improvement in their quality of life, as indicated by various scores measuring skin and itch severity. On the other hand, while 120 mg doses led to further enhancements, mild adverse effects were noted. Thankfully, no significant adverse effects were reported with the lower dose.
In summary, ligelizumab shows great promise as an effective treatment for CSU, significantly alleviating symptoms and enhancing patients' well-being when compared to placebo, albeit with some mild side effects at higher doses.
To gain a clearer understanding, we reviewed various studies, focusing on randomized controlled trials comparing ligelizumab with a placebo. Our analysis included data from 2,581 patients and revealed that ligelizumab significantly improved symptoms. A crucial finding was that the 72 mg dose of ligelizumab effectively reduced itch severity and overall hives activity.
We observed that patients receiving this dosage experienced a marked improvement in their quality of life, as indicated by various scores measuring skin and itch severity. On the other hand, while 120 mg doses led to further enhancements, mild adverse effects were noted. Thankfully, no significant adverse effects were reported with the lower dose.
In summary, ligelizumab shows great promise as an effective treatment for CSU, significantly alleviating symptoms and enhancing patients' well-being when compared to placebo, albeit with some mild side effects at higher doses.
6
No allergic reactions
Most Useful Review
This is by far my favourite whey protein and the only one I can consume without severe allergies. The taste is just as described and does not resemble chalk! It’s delicious! I’ve tried vanilla ice cream and Double Rich Chocolate flavours, both are scrumptious. Previously, I’ve had life-threatening allergic reactions from other brands leading to hives and breathing difficulties, but this product has been fine for the last 3 months. I’ve included it in my daily smoothie, and it tastes delightful!
