Supplement Facts
Serving Size: 1 VegCap
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid, Acerola Cherry, Rose Hips)
1,000 mg
1,111%
The product is found useful for the following medical conditions
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 311 Reviews
8.9
7
Effectiveness of Vitamin C on Colds
Vitamin C for the common cold and pneumonia.
Most Relevant Research
We explored the effects of vitamin C on the common cold and pneumonia by examining a range of studies. Interestingly, research on animals suggests that vitamin C may have protective effects against infections. However, when it comes to preventing colds in the general population, taking more than 1 gram of vitamin C per day didn’t show significant benefits.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
But there's a twist! Participants engaged in heavy physical activities saw their cold incidence reduced by half with vitamin C supplementation. Additionally, regular intake of 1 gram or more daily was linked to a 15% decrease in cold severity. While some therapeutic trials showed inconsistent results when vitamin C was taken after cold symptoms appeared, two studies did indicate that larger doses (6-8 grams per day) could effectively shorten the duration of colds compared to lower doses.
Our investigation also looked into pneumonia, but the studies were conducted in unique settings, such as a boarding school and military recruits. This makes it hard to generalize the findings to the wider population. Yet, some trials suggested benefits for pneumonia patients. Finally, the role of vitamin C in treating COVID-19 and sepsis remains unclear, with mixed results.
Given that vitamin C seems to alleviate symptoms and shorten the duration of colds, while being safe and affordable, it might be worth considering a dose of 6-8 grams per day to see if it helps at an individual level.
9.5
Immune support boost
Most Useful Review
Take it, you won't regret it! This excellent quality vitamin has a sustained release, with half absorbed immediately and half entering the body over 12 hours. One capsule per day is standard, but during colds, you can take up to six capsules daily for the first few days to enhance immunity. Symptoms improve quickly, and I felt better by the second day without severe illness. It’s non-allergenic, which is a relief for someone like me who previously reacted to Russian vitamin C. This option is also significantly cheaper than what’s available locally. Please click "thumb up" if you find this useful!
Flu details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.2
USERS' SCORE
Good
Based on 43 Reviews
8.9
8
Vitamin C mitigates flu pneumonia
A new mechanism of vitamin C effects on A/FM/1/47(H1N1) virus-induced pneumonia in restraint-stressed mice.
Most Relevant Research
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
9.5
Effective dosage
Most Useful Review
No colds or flu so far since taking this. We take about 3000 mg per day and have avoided any illness, even around snotty-nosed grandkids. Building your immune system is key, and Vitamin C is essential.
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.8
9.5
Effective immunity boosting
Most Useful Review
Good quality. I'm 45 and take 2000mg of vitamin C and 1000mg of vitamin B5 every morning and evening for my skin and to strengthen my immune system. When suffering from a chronic cough, I increase the intake to 2000mg-3000mg of vitamin C and 2000mg of vitamin B5 every two hours until the cough subsides, which has always worked for me.
Heartburn details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 19 Reviews
8.8
8
Vitamin C reduces heartburn symptoms
The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial.
Most Relevant Research
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
9.5
No heartburn observed
Most Useful Review
This product was recommended by YouTube, and I repurchased it because I appreciate that it does not cause heartburn and is absorbed slowly. I take two tablets daily due to my high dosage requirements, but my skin has become radiant, and I haven't experienced significant pain while using it. Therefore, I will continue to take it.
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 9 Reviews
8.7
8
Pleuran and Vitamin C aid asthma
Beneficial effects of pleuran on asthma control and respiratory tract-infection frequency in children with perennial asthma.
Most Relevant Research
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.
While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
9.5
No allergies experienced
Most Useful Review
One capsule per day suffices! This long-acting formulation aids in the absorption of Vitamin C throughout the day. I take one daily without any issues of allergies, and it absorbs well. If swallowing is difficult, the capsule can be opened and its contents emptied.
Common Cold details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
USERS' SCORE
Good
Based on 61 Reviews
8.6
8
Vitamin C reduces cold severity
Vitamin C reduces the severity of common colds: a meta-analysis.
Most Relevant Research
We explored how vitamin C affects the severity of common colds through a comprehensive review of available studies. By including only randomized, placebo-controlled trials where participants received at least 1 gram of vitamin C daily, we aimed to investigate both the overall duration of colds and the intensity of symptoms experienced.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
Our analysis found that vitamin C significantly reduced the severity of cold symptoms by about 15%. Interestingly, it appears that the benefits are more pronounced for those experiencing severe symptoms compared to mild ones. In specific comparisons, vitamin C didn’t substantially affect the duration of mild symptoms but had a notable impact on how long severe symptoms lasted.
This insight is crucial, as the common cold often leads to absenteeism at work and school, with more severe symptoms playing a key role in this setback. By highlighting vitamin C's greater effectiveness against intense cold symptoms, we suggest that future research should continue to look into how this vitamin can be utilized in managing cold severity.
9.5
Immunity booster
Most Useful Review
Take it; you won't regret it! This high-quality vitamin C has sustained release, absorbing half immediately and the rest over 12 hours. I take one daily, but during common colds, I consume up to six capsules to boost my immunity. It significantly speeds up recovery without causing allergies.
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
No rashes experienced
Most Useful Review
Great product. For me, the most important aspect is that it doesn't cause stomach pains after taking it, nor does it lead to rashes, as I have allergies. During a time when one might catch acute respiratory diseases, it's invaluable! The dosage and packaging are convenient. It's reasonably priced and lasts long enough. I purchase it for the whole family.
Ulcer details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.8
USERS' SCORE
Good
Based on 5 Reviews
8.6
8
Vitamin C reduces gastric ulcers
Vitamin C modulates adrenaline-augmented gastric injury via cardiac troponin/creatine kinase pathway in Wistar rats.
Most Relevant Research
We observed the potential benefits of vitamin C in managing gastric ulcers under conditions of myocardial injury, which was induced using adrenaline in our study. Thirty Wistar rats were carefully divided into five groups, ensuring a control group for comparison.
The rats that received adrenaline alone showed increased gastric secretions and elevated markers related to heart injury. However, those pre-treated with vitamin C experienced a notable reduction in ulcer severity and excessive gastric secretions.
Interestingly, when we administered vitamin C before the adrenaline exposure, we found that it significantly decreased both the volume of gastric juice and total acidity, while also enhancing some protective factors. In essence, our research indicates that vitamin C may play a protective role in gastric health, particularly amid the stressful conditions created by adrenaline.
The rats that received adrenaline alone showed increased gastric secretions and elevated markers related to heart injury. However, those pre-treated with vitamin C experienced a notable reduction in ulcer severity and excessive gastric secretions.
Interestingly, when we administered vitamin C before the adrenaline exposure, we found that it significantly decreased both the volume of gastric juice and total acidity, while also enhancing some protective factors. In essence, our research indicates that vitamin C may play a protective role in gastric health, particularly amid the stressful conditions created by adrenaline.
8.3
Reduced occurrence
Most Useful Review
Since I began taking Vitamin C, I've experienced fewer mouth ulcers.
Blood Clot details
SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.7
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Vitamin C enhances blood clotting
Ascorbic acid improves thrombotic function of platelets during living donor liver transplantation by modulating the function of the E3 ubiquitin ligases c-Cbl and Cbl-b.
Most Relevant Research
We sought to understand how ascorbic acid, commonly known as vitamin C, impacts blood clotting during living donor liver transplantation (LDLT). In our study, we analyzed blood samples from 21 recipients before and after their surgeries.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
We employed a well-structured approach, using rotational thromboelastography (TEG) and western blot analysis to scrutinize fibrinolysis and the functionality of specific proteins involved in clotting. Blood samples were tested in three distinct groups, one receiving vitamin C, to see its effects on clot rigidity and fibrinolysis.
Our findings revealed that ascorbic acid notably reduced fibrinolysis, which refers to the breakdown of blood clots, and improved the rigidity of the clots formed. Additionally, we observed that levels of a protein called Cbl-b were higher in those receiving vitamin C, while another protein, c-Cbl, showed reduced phosphorylation. These functional changes might explain how vitamin C supports better clotting during surgeries.
This study indicates that vitamin C could be a beneficial treatment to consider during LDLT to manage hyperfibrinolysis, thus promoting better outcomes for patients undergoing these complex procedures.
8.8
Enhances blood clarity
Most Useful Review
After taking various vitamin C supplements for my mega-vitamin challenge, my blood test revealed an increase in vitamin C levels. The combination with rosehip and acerola may enhance effectiveness. I find the capsules easy to swallow and take two daily for optimal benefits.
Cancer details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.
Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
8.8
Recommended for recovery
Most Useful Review
This high concentration vitamin has proven very effective. I recommended it to a friend who had cancer surgery, and the doctor confirmed it was a good vitamin choice for them.
Cold Sores details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 4 Reviews
8.4
9
Vitamin C alleviates cold sores
Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution.
Most Relevant Research
We investigated how an ascorbic acid-based solution could help treat recurrent cold sores, also known as mucocutaneous herpes. This study was carefully designed as a randomized, double-blind, placebo-controlled trial, which helps ensure the results are reliable and trustworthy.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
Participants used a strong solution of Ascoxal, rich in vitamin C, applied to their cold sores multiple times on the first day of the outbreak. We monitored various symptoms daily, including the severity of scabs, redness, and blisters, comparing the experiences of those using the vitamin C solution to a placebo group.
Our findings were promising: the active treatment resulted in fewer days with scabbing and less severe symptoms overall. Moreover, those using the vitamin C solution showed reduced persistence of scabs compared to the placebo group, along with a lower frequency of detected herpes virus after treatment.
In conclusion, this brief course of vitamin C treatment appears to have significant clinical benefits against cold sores, opening the door for future research on more extensive and frequent treatment regimes.
9.5
Cold sores prevention
Most Useful Review
I began taking a high dose of 1 capsule three times daily at the first signs of a cold. Consequently, during Covid, I only lost my sense of smell and had no fever. I also took vitamin C, omega 3, and vitamin D3. My husband had Covid with pneumonia but managed without antibiotics, solely relying on vitamins.
Diarrhea details
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
Vitamin C improves diarrheic calf health
Does vitamin C supplementation in milk improve growth and health of diarrheic calves?
Most Relevant Research
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.
The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
8.8
Supports recovery well
Most Useful Review
My naturopath advised me to take time-released Vitamin C for recovery after major surgery. This product works well for me and doesn't upset my stomach. While taking too much can cause diarrhea, I prefer the 500 mg version as it allows me to adjust my intake. I’ve recovered well and believe this has significantly aided my healing process. The smell and taste are also not bothersome.
Pots details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.4
8.8
Reduces age spots
Most Useful Review
I take vitamin C to reduce age spots and to aid recovery during the first three days of an attack. The format is convenient and the quality is reliable.
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
Vitamin C impacts autoimmune response
Ascorbic acid alleviates rheumatoid arthritis by inhibiting the production of autoantibodies.
Most Relevant Research
We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
8.8
Positive effect noted
Most Useful Review
Excellent! I initially tried the tablet form from the same brand, but found it hard to swallow; it melts in the mouth and tastes sour. I ordered the capsule version instead, which is easy to take and stress-free. This is recommended for those who struggle with large tablets. I’m pleased that Solaray's time-release Vitamin C seems effective; my dullness has improved in the morning and before bed, giving me a sense of clarity regarding my autoimmune disorder.
Back Pain details
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.3
USERS' SCORE
Good
Based on 5 Reviews
8.2
4
Vitamin C's limited impact on pain
The Efficacy of Vitamin C on Postoperative Outcomes after Posterior Lumbar Interbody Fusion: A Randomized, Placebo-Controlled Trial.
Most Relevant Research
We conducted a year-long study to investigate the effects of vitamin C on postoperative pain and recovery after a specific type of spine surgery known as posterior lumbar interbody fusion (PLIF). In this randomized, placebo-controlled trial, we worked with 123 patients, dividing them into two groups: one receiving vitamin C and the other a placebo.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
Our main focus was to see how vitamin C influenced lower back pain measured by a visual analogue scale. While we found that there was no significant difference in pain levels at the one-year mark between the two groups, there was a silver lining. We observed that vitamin C appeared to enhance functional improvement, especially within the first three months after surgery.
So, while vitamin C didn’t seem to directly reduce pain intensity after surgery, it could play a role in supporting early recovery and everyday function. This finding may encourage further exploration into vitamin C's potential benefits in postoperative care for patients undergoing spine surgeries.
9.5
Reduced fever
Most Useful Review
When I have a fever of 38-39 degrees, taking 1-2 vitamin C tablets every 5-30 minutes helps reduce it within 3-4 hours. It also alleviates chills, but frequent intake may upset my stomach.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Good
Based on 15 Reviews
8.1
7
Vitamin C aids immune function
The clinical course of interstitial pneumonia alias chronic fatigue syndrome under the control of megadose vitamin C infusion system with dehydroepiandrosterone-cortisol annex.
Most Relevant Research
We examined how a combination of megadose vitamin C infusions and other treatments might help manage chronic fatigue syndrome, particularly in the context of interstitial pneumonia. Our findings were based on nearly a decade of treating patients, allowing us to gather valuable insights.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
We observed that the long-term use of this treatment system significantly reduced the risk of pneumonia recurrence. It also appeared to help prevent the emergence of certain cancers in older patients suffering from interstitial pneumonia. Surprisingly, we found a link between interstitial pneumonia and an increased risk of depression, likely driven by prolonged glucocorticoid use.
While some patients showed promise under this treatment, those battling both interstitial pneumonia and depression responded less favorably. We suggested that increasing the amount of dehydroepiandrosterone in the treatment could be beneficial. Throughout our experience, we noted that the characteristics of chronic fatigue syndrome align closely with those of interstitial pneumonia, arguing against the notion that they should be viewed as separate conditions.
Overall, our approach not only alleviated inflammation but did not suppress the fibrotic processes in the long run. We made modifications to the treatment to lower the risks of vascular complications. The main strength of our treatment lies in creating a hormonal environment that helps tackle immune deficiencies using vitamin C, which faces lower resistance in the body compared to steroid treatments.
9.5
Immune support
Most Useful Review
Vitamin C is the best for enhancing my immune system, especially during outbreaks of acute respiratory infections and chronic fatigue syndrome. It helps speed up recovery and regulates blood health. I recommend it highly for anyone dealing with fatigue or stress.
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
9.5
Reduced throat pain
Most Useful Review
Well, I use it to boost my immunity, and when I experience a sore throat, it helps me. After taking it once, I've noticed the pain disappears after only a few hours.
Liver Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.9
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.3
9
Vitamin C reduces liver injury
The Effect of Ascorbic Acid on Hepatic Ischaemia-Reperfusion Injury in Wistar Rats: An Experimental Study.
Most Relevant Research
We evaluated how vitamin C, also known as ascorbic acid, can help protect the liver during procedures that temporarily cut off blood flow—a process known as ischaemia followed by reperfusion. In this study, we used thirty-six male Wistar rats, split into control groups and experimental ones. Each group received the same total dose of vitamin C, administered at different times: either before the ischaemia, before the reperfusion, or both.
Our findings showed that the animals given vitamin C before both the ischaemia and reperfusion had improved outcomes. They had lower levels of liver enzymes, indicating less liver damage, and showed reduced inflammation. Additionally, their portal blood flow was better when compared to the other groups. Overall, our results suggest that administering vitamin C at specific times can significantly reduce liver injury associated with ischaemia-reperfusion.
This study highlights the potential of vitamin C as a protective agent in situations where liver damage is a concern during surgeries or treatments involving blood flow disruption.
Our findings showed that the animals given vitamin C before both the ischaemia and reperfusion had improved outcomes. They had lower levels of liver enzymes, indicating less liver damage, and showed reduced inflammation. Additionally, their portal blood flow was better when compared to the other groups. Overall, our results suggest that administering vitamin C at specific times can significantly reduce liver injury associated with ischaemia-reperfusion.
This study highlights the potential of vitamin C as a protective agent in situations where liver damage is a concern during surgeries or treatments involving blood flow disruption.
1.3
Worsened liver function
Most Useful Review
This vitamin C did not meet my expectations. I found its time-release features ineffective, and I experienced a decline in liver function. Overall, my previous vitamin C source seemed much better. I question the claims about its effectiveness.
Pelvic Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.2
0
Kidney pain
Most Useful Review
Cause my kidney pain.
