Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
L-Lysine (as L-lysine HCl) (Free Form)
500 mg
**
The product is found useful for the following medical conditions
Acne details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.7
9
We explored the effects of G2 lysine dendrimer on acne and how it can help restore balance to our skin microbiome. Acne is a persistent skin condition that brings about discomfort and concerns for many. Traditional treatments can often lose their effectiveness over time or lead to unwanted side effects. So, our goal was to see if this new approach could offer a gentler solution.
Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.
We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.
Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.
We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.
Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
10
Hormonal acne cure
Most Useful Review
15 people found this helpful
Cures hormonal acne! I’ve been amazed by this supplement. After struggling with hormonal acne for two years, I found that it has practically cured my cystic pimples. Despite being cautious with my diet, the breakouts stopped once I began taking this. I went for the 500 mg size since I have trouble swallowing large pills, and one a day does the trick.
Updated: Oct 2025
Common Cold details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Fast cold sore relief
Most Useful Review
2 people found this helpful
At the first sign of a cold sore, I take this supplement 2-3 times a day on an empty stomach. It helps the sore heal faster and with less discomfort. I always keep it on hand.
Updated: Mar 2026
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Noticeably better skin
Most Useful Review
I see the result; my skin is evidently better, and the rashes on my face have vanished. My hair is falling out much less as well. I have been taking it for less than a month.
Updated: Mar 2026
Anxiety details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
Anxiety reduction observed with lysine
We investigated how L-lysine, an essential amino acid, influences anxiety and body weight. The study involved administering two doses of L-lys to rats over 20 days.
We found that while L-lys didn't affect food intake, it did lead to weight reduction and showed signs of anxiolytic effects on the first day. Notably, repeated doses increased serotonin levels in key brain areas, which may explain its calming effects.
However, the study's outcomes indicate that L-lys may not dramatically alter anxiety compared to other treatments.
We found that while L-lys didn't affect food intake, it did lead to weight reduction and showed signs of anxiolytic effects on the first day. Notably, repeated doses increased serotonin levels in key brain areas, which may explain its calming effects.
However, the study's outcomes indicate that L-lys may not dramatically alter anxiety compared to other treatments.
9
Helps with anxiety
Most Useful Review
2 people found this helpful
Perfectly! I take it on an empty stomach before meals. Lysine supplementation can assist those who are depressed and relieve anxiety and stress symptoms.
Updated: Mar 2026
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 5 Reviews
8.5
9
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.
After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
9
Herpes suppression
Most Useful Review
8 people found this helpful
Lysine is essential for those with an autoimmune disorder like herpes. It prevents the virus from multiplying, greatly reducing outbreaks. After three months of 1000 mg daily, my herpes stopped appearing, even after minor colds or stress. It’s been a year now without any symptoms. I recommend this to friends and family suffering from herpes.
Updated: Apr 2025
Bone Pain details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
We examined the effects of an arginine-lysine-lactose combination on bone pain in older adults with osteoporosis. In our study of 40 participants, we compared those receiving this treatment to a control group receiving carbocalcitonin alone.
After six months, we observed that the group treated with arginine-lysine-lactose showed greater improvements, including increased bone density and reduced pain. These benefits likely stem from enhanced calcium absorption linked to lysine and lactose.
Overall, the combination proved effective in alleviating bone pain symptoms associated with aging.
After six months, we observed that the group treated with arginine-lysine-lactose showed greater improvements, including increased bone density and reduced pain. These benefits likely stem from enhanced calcium absorption linked to lysine and lactose.
Overall, the combination proved effective in alleviating bone pain symptoms associated with aging.
9
Pain relief
Most Useful Review
This product is essential for when I have aphthae and sores in my mouth. It significantly reduces my pain level and helps speed up recovery. There is no substitute for this remedy in treating bone pain.
Updated: Apr 2025
Shingles details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 3 Reviews
8.5
8
We explored the effectiveness of lysine supplementation in treating herpes infections through a survey of 1,543 participants after a six-month trial. The findings revealed that a substantial 84% reported that lysine helped prevent recurrences or reduced the frequency of outbreaks.
Notably, only 8% of users described their symptoms as severe while taking lysine, compared to 79% who felt that way without it. Healing times improved significantly; 83% felt lesions healed in five days or less with lysine, while 90% said healing took longer without it. Overall, 88% regarded lysine as an effective treatment.
Notably, only 8% of users described their symptoms as severe while taking lysine, compared to 79% who felt that way without it. Healing times improved significantly; 83% felt lesions healed in five days or less with lysine, while 90% said healing took longer without it. Overall, 88% regarded lysine as an effective treatment.
9
Reduced breakout frequency
Most Useful Review
16 people found this helpful
You have shingles? This has helped stop my recurring shingles! It's essential to talk to a holistic doctor for dosage. This has helped my shingles significantly, although I might still have minor breakouts when stressed.
Updated: Mar 2026
Depression details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
7.5
Mood improvement
Most Useful Review
1 people found this helpful
Lysine is an essential amino acid that must be obtained from food or supplements. It aids athletes in muscle recovery, supports skin and hair health, and helps those prone to depression. It also assists the elderly in preventing osteoporosis and those suffering from herpes in mitigating symptoms.
Updated: Apr 2025
Cold details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 43 Reviews
8.3
9
We set out to uncover how certain amino acids, particularly lysine, help with cold acclimation. Over three months, 20 men were monitored for physiological changes after being exposed to cold.
We found that continuous exposure led to faster cold-induced vasodilation and improved finger temperature. Notably, lysine was the only amino acid that significantly changed and positively correlated with these improvements in cold response.
In mouse trials, lysine supplementation helped maintain core body temperature during cold exposure, indicating its role in supporting metabolic adjustments to the cold.
We found that continuous exposure led to faster cold-induced vasodilation and improved finger temperature. Notably, lysine was the only amino acid that significantly changed and positively correlated with these improvements in cold response.
In mouse trials, lysine supplementation helped maintain core body temperature during cold exposure, indicating its role in supporting metabolic adjustments to the cold.
8
Helps with colds
Most Useful Review
19 people found this helpful
It helps me; I drink it in courses. It aids with frequent colds on the lips!
Updated: Mar 2026
Herpes details
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
5.3
USERS' SCORE
Good
Based on 95 Reviews
8.1
4
We explored how dietary changes and supplements impact skin conditions like herpes labialis. Specifically, we found that L-lysine can be effective as a preventive measure against herpes outbreaks. However, it doesn’t help shorten the duration of active lesions once they appear. Despite popular beliefs around diet's role in such conditions, we observed that high-quality evidence supporting dietary changes for other skin issues like rosacea is lacking. Additionally, certain vitamins and minerals showed promise in treating conditions like hidradenitis suppurativa.
7.5
Reduces herpes relapses
Most Useful Review
120 people found this helpful
One of the good options for L-lysine, with a dosage of 500mg. L-lysine promotes healing of wounds and has antiviral activity, especially against the herpes virus, significantly increasing the intervals between relapses. The composition is excellent and the quality is very good. I recommend it to everyone.
Updated: Mar 2026
Data last updated:
