Supplement Facts
Serving Size: 2 Caplets
Serving Per Container: 100
Amount Per Serving
%DV
Total Sugars
0 g
**
Includes 0 g Added Sugars
0%*
Sugar Alcohols
0 g
**
Vitamin D
12.5 mcg (500 IU)
63%
Calcium
400 mg
31%
Sodium
5 mg
<1%
The product is found useful for the following medical conditions
Leg Cramps details
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
5.9
USERS' SCORE
Good
Based on 4 Reviews
8.3
9
Calcium dobesilate reduces leg cramps
We examined the benefits of calcium dobesilate for patients suffering from chronic venous insufficiency (CVI), particularly focusing on how it impacts symptoms like leg cramps. In a systematic evaluation of ten different clinical trials involving 778 patients, we compared the effects of calcium dobesilate to a placebo.
Our analysis found that calcium dobesilate significantly reduced night cramps, helping patients nearly twice as much as those who received a placebo. The number needed to treat for this relief was calculated to be 8, indicating that for every eight patients treated with calcium dobesilate, one experienced noticeable improvement.
Moreover, patients also reported less discomfort, with a number needed to treat of 4 for that symptom. Interestingly, we noted that those with more severe symptoms experienced even greater relief, suggesting that calcium dobesilate is particularly effective for patients with advanced CVI. However, both doses tested—1,000 mg and 1,500 mg—proved equally effective, which is good news as it suggests that a lower dose might suffice.
Additionally, we found that adverse events were not significantly different from the placebo group, indicating a favorable safety profile. While calcium dobesilate shows promise, we acknowledge the need for further studies to solidify these findings and explore its efficacy in various CVI stages.
Our analysis found that calcium dobesilate significantly reduced night cramps, helping patients nearly twice as much as those who received a placebo. The number needed to treat for this relief was calculated to be 8, indicating that for every eight patients treated with calcium dobesilate, one experienced noticeable improvement.
Moreover, patients also reported less discomfort, with a number needed to treat of 4 for that symptom. Interestingly, we noted that those with more severe symptoms experienced even greater relief, suggesting that calcium dobesilate is particularly effective for patients with advanced CVI. However, both doses tested—1,000 mg and 1,500 mg—proved equally effective, which is good news as it suggests that a lower dose might suffice.
Additionally, we found that adverse events were not significantly different from the placebo group, indicating a favorable safety profile. While calcium dobesilate shows promise, we acknowledge the need for further studies to solidify these findings and explore its efficacy in various CVI stages.
9
Improved cramps
Most Useful Review
Good quality with high calcium content, suitable for all ages. It has helped significantly with leg cramps, contributing to bone development.
Updated: Apr 2026
Osteoporosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 31 Researches
7.5
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.4
9
We examined a collection of randomized controlled trials to determine the impact of calcium plus vitamin D supplementation on fracture prevention.
The results revealed a promising 15% reduction in total fractures and a remarkable 30% drop in hip fractures among those taking these supplements.
This convincing evidence supports the recommendation of calcium and vitamin D for reducing fracture risk, especially in older adults, whether living at home or in care facilities.
The results revealed a promising 15% reduction in total fractures and a remarkable 30% drop in hip fractures among those taking these supplements.
This convincing evidence supports the recommendation of calcium and vitamin D for reducing fracture risk, especially in older adults, whether living at home or in care facilities.
7.5
Easily absorbed
Most Useful Review
9 people found this helpful
I trust Citrical for my osteoporosis management as I have been taking calcium supplements daily since my diagnosis two years ago. It absorbs easily, and I appreciate that I can take it with or without food. Although I expected the petites to be smaller, they assist well with swallowing.
Updated: Mar 2026
Data last updated:
