'
Supplement Facts
Serving Size: 1 Vegetarian Tablet
Amount Per Serving
%DV
Vitamin C (as Ester-C® Calcium Ascorbate)
1,000 mg (1 g)
1,111%
Calcium (as Ester-C® Calcium Ascorbate)
108 mg
8%
Citrus Bioflavonoids ComplexCitrus Bioflavonoids (Citrus spp.) (fruit), Sweet Orange, Tangerine, Lime, Lemon, Acerola, Rutin, Hesperidin Complex (Citrus spp.) (fruit), Naturally Occurring Vitamin C Metabolites
200 mg
**

The product is found useful for the following medical conditions

Headache

SCIENTIFIC SCORE
Most Likely Effective
Based on 2 Researches
8
USERS' SCORE
Excellent
Based on 2 Reviews
9.8
8
Vitamin C intake reduces migraines
Association between dietary vitamin C intake and migraine in adults: A cross-sectional study of the National Health and Nutrition Examination Survey.
Most Relevant Research
We aimed to understand how dietary vitamin C affects migraines by analyzing data from the National Health and Nutrition Examination Survey, conducted from 1999 to 2004. In this survey, we identified adults who reported experiencing severe headaches or migraines over the past three months.

Our findings were quite revealing. Out of 4,101 participants, 702 individuals reported having a migraine, which represents about 17% of the group. We discovered an interesting trend: higher dietary vitamin C intake seemed to correlate with a lower likelihood of experiencing migraines. Specifically, participants with the highest vitamin C intake had a 36% reduced odds of suffering from migraines compared to those with the lowest intake.

We employed various statistical methods to confirm our results, including logistic regression and restricted cubic spline regression, which showed a clear linear relationship between vitamin C intake and the frequency of migraines.

Overall, this study suggests that increasing our dietary vitamin C might help minimize migraines, which is promising news for those who suffer from these intense headaches. However, as with all studies, further research is necessary to solidify these findings and fully understand the relationship between vitamin C and headache relief.
10
Headaches disappeared
Most Useful Review
I have taken vitamin C since my adolescence to strengthen my immunity. It has significantly helped with my headaches, which initially arose from events with little oxygen. After starting the vitamin, my headaches diminished and ultimately disappeared altogether. Now, I take a daily high-dose vitamin C supplement, mostly in powder form. I haven’t been ill for years, and I hope it continues to strengthen my immune system during this pandemic.

Reflux

SCIENTIFIC SCORE
Most Likely Effective
Based on 2 Researches
7.5
USERS' SCORE
Excellent
Based on 4 Reviews
9.7
8
Vitamin C aids omeprazole therapy
Antioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis.
Most Relevant Research
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.

We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.

This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
10
No reflux experienced
Most Useful Review
I find Ester-C to be the best vitamin C as it uses calcium ascorbate, which prevents heartburn or reflux. With my sensitive stomach, I handle this product very well, and it contains no added sugar or harmful sweeteners. It’s worth noting that sugar can hinder vitamin C absorption, so this formulation is ideal.

Acne

SCIENTIFIC SCORE
Most Likely Effective
Based on 16 Researches
7.6
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9
Vitamin C shows effectiveness for acne
Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial.
Most Relevant Research
In our recent study, we set out to explore the effectiveness of a 5% sodium L-ascorbyl-2-phosphate lotion, a stable form of vitamin C, for treating acne. We conducted a double-blind, controlled trial with 50 participants over 12 weeks, where half used the vitamin C lotion and the other half received a placebo.

Our findings revealed significant improvements in acne symptoms for those using the vitamin C lotion compared to the placebo group. We measured outcomes through various assessments, including a global evaluation by investigators and self-reported assessments by the subjects, along with lesion counts.

The results showed that the vitamin C lotion was not only effective but also well-tolerated, with side effects similar to those seen with the placebo. This adds a promising tool to the options available for acne treatment, suggesting that vitamin C might play a valuable role in skincare regimens aimed at combating acne.

Overall, our study supports the idea that vitamin C, in the form of sodium L-ascorbyl-2-phosphate, can help reduce acne, making it a noteworthy addition to acne treatment strategies.
9.5
Fading acne marks
Most Useful Review
The effect is remarkable; the acne marks fade rapidly.

Asthma

SCIENTIFIC SCORE
Most Likely Effective
Based on 1 Researches
8
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
8
Pleuran and Vitamin C improve asthma
Beneficial effects of pleuran on asthma control and respiratory tract-infection frequency in children with perennial asthma.
Most Relevant Research
We conducted a thorough investigation to examine how vitamin C, when combined with pleuran (a natural extract from mushrooms), influences asthma control and respiratory health in children with partially controlled perennial asthma. Our study was a double-blind, placebo-controlled clinical trial involving 230 children aged 7 to 17 years, split evenly into an active treatment group and a placebo group.

Over a 24-week period, children in the active group received both pleuran and vitamin C, while the placebo group received vitamin C alone. It was exciting to find that children younger than 12 years who received the combination treatment showed notable improvement in their control of asthma symptoms compared to those on placebo. Additionally, older children in the active group reported fewer respiratory infections, an important benefit for their overall health.

By the end of our 48-week study, we saw a significant improvement in asthma control in a high percentage of children receiving the active treatment. Notably, this combination appeared safe, with no serious side effects reported. Overall, our findings suggest that while vitamin C's isolated effects can't be fully assessed due to its combination with pleuran, the combined treatment offers promising benefits for managing asthma in children.
9.5
Effective asthma treatment
Most Useful Review
Fantastic! Vitamin C has been the only thing that effectively helps my asthma and allergies. This brand’s formulation is the best, and I won’t let my supply run out as I rely on it heavily. I find the capsules easier to swallow compared to tablets.

Chest Pain

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 4 Reviews
9.5
9.5
Chest pain relief
Most Useful Review
Helped me manage the disease effectively. Initially, I intended to cut the tablets for a 500 mg dose daily but overlooked that these were capsules. After my children brought home an illness, I took one capsule with a meal, and my symptoms improved far quicker than before. I appreciated the non-acidic vitamin C, which didn't cause me chest pain as lemon water did, as I had been under a gastroenterologist’s care. Very satisfied, indeed!

Diarrhea

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
6.5
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9
Vitamin C improves diarrheic calf health
Does vitamin C supplementation in milk improve growth and health of diarrheic calves?
Most Relevant Research
We investigated how adding vitamin C to milk influences the growth and health of young calves, particularly those experiencing diarrhea. The study involved 48 Holstein calves, which were sorted into two groups based on their health status: healthy calves and those with diarrhea. Each calf was fed the same amount of pasteurized milk and monitored until they reached 74 days of age.

Calves that received vitamin C showed an impressive increase in weight by weaning—74.3 kg compared to 72.2 kg for those without vitamin C. Additionally, calves treated with vitamin C demonstrated improved blood antioxidant levels, suggesting better overall health. Notably, calves suffering from diarrhea benefitted significantly from the vitamin C, needing fewer days of medication for treatment compared to those who did not receive the supplement.

The research highlights that vitamin C can play a critical role in supporting the health of calves during episodes of diarrhea. This is especially relevant for those that faced even mild cases early in life, as they seemed to gain the most benefits from the supplementation. Overall, it appears that vitamin C can positively impact both growth and health in calves suffering from diarrhea.
9.5
No stomach issues
Most Useful Review
Great! I love this brand and especially this item, which doesn’t cause any diarrhoea or stomach issues, even on an empty stomach.

Gastritis

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 11 Reviews
9.5
9.5
No irritation
Most Useful Review
The composition is rich: vitamin C in a non-acidic form, which does not irritate the gastric mucosa, along with trace elements like calcium and coenzymes such as bioflavonoids and rutin. The vitamin C dosage is therapeutic at 1000 mg, and I wouldn't recommend taking this supplement long-term. Thanks to the calcium ascorbate form, my gastritis wasn't aggravated during use.

Heart Disease

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9.5
Immune support noted
Most Useful Review
Vitamin C is vital for combating colds and flu. A doctor advised me to take it before my surgery, and later, I noticed its impact during my father's chemotherapy. While he maintained his health, I ensured I took Vitamin C during my heart surgery and have since avoided flu and colds, even while caring for my grandchildren. I find Ester C particularly effective, as it doesn't cause the burning sensation typical of other Vitamin C products.

Pneumonia

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9.5
Strength regained
Most Useful Review
I have relied on this vitamin for seven years. During my pneumonia illness, I took 2 grams three times daily, which helped me regain strength. I attribute my recovery from this serious disease to it, despite two affected lung lobes.

Prostate Cancer

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9.5
Vital immune support
Most Useful Review
It works! I find this particular Ester-C absorbs more readily and is highly effective. I can increase the dosage without any stomach upset. I swear by it; it is vital for my immune system following prostate cancer. I make an effort to maintain a supply at home and double up whenever I need to fend off colds. Great product!

Tonsillitis

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 1 Reviews
9.5
9.5
No infections noted
Most Useful Review
I fell ill with a crown and sought ways to boost my immunity. The nutritionist suggested vitamin C in this formulation. I have enough capsules for three months; the daily dose is 1000mg, and in the off-season, I can take 2000mg for a month. The results have been outstanding. I've historically caught colds in autumn, with my chronic tonsillitis worsening each year. Surprisingly, I’ve stayed healthy this autumn, even in cold spells. After the first jar, I will definitely continue to order this, despite the high price.

Allergies

SCIENTIFIC SCORE
Most Likely Effective
Based on 1 Researches
8
USERS' SCORE
Excellent
Based on 8 Reviews
9.3
8
Pleuran and Vitamin C aid asthma
Beneficial effects of pleuran on asthma control and respiratory tract-infection frequency in children with perennial asthma.
Most Relevant Research
We conducted a thorough evaluation of how vitamin C, when combined with pleuran, impacts asthma control and respiratory issues in children suffering from perennial asthma. The study was meticulously designed as a double-blind, placebo-controlled trial involving 230 children aged 7 to 17 years. This means that neither the participants nor the researchers knew who was receiving the active treatment or the placebo, ensuring the findings were reliable.

The results were promising, especially for children under 12 years. They showed significant improvements in asthma control compared to those receiving only the placebo treatment. Meanwhile, older children (12 years and above) experienced fewer respiratory infections with the combination treatment. Overall, by the end of the 48 weeks, a majority of children on the pleuran and vitamin C treatment reported better asthma control compared to those on the placebo.

While the combination of pleuran and vitamin C was indeed beneficial for managing asthma, we must note that the study did not specifically isolate the effect of vitamin C alone on allergies or asthma. Thus, it is hard to draw definitive conclusions about vitamin C's effectiveness independently from pleuran. However, the approach suggested that using these supplements together could offer a helpful boost in managing asthma symptoms.
9.5
Immunity improvement
Most Useful Review
It really boosts my immunity, especially during seasonal changes. I'm far less frequent at the doctor’s for allergies now.

Breast Cancer

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 2 Reviews
9.2
9.5
Vital for immunity
Most Useful Review
It works! This particular Ester-C is absorbed readily and is very effective. I can increase the dosage without upsetting my stomach, which is vital for my immune system after breast cancer. I always keep it on hand in my home and “double up” when necessary to fend off colds.

Heartburn

SCIENTIFIC SCORE
Most Likely Effective
Based on 1 Researches
8
USERS' SCORE
Excellent
Based on 16 Reviews
9.2
8
Vitamin C reduces heartburn symptoms
The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial.
Most Relevant Research
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
9.5
No heartburn
Most Useful Review
Ester-C is a non-acidic form of vitamin C that doesn’t irritate the stomach due to its neutral pH. It’s great for those who suffer from heartburn or indigestion when taking regular ascorbic acid. This combination of vitamin C and calcium is beneficial, providing both in a convenient tablet. I recommend taking it as advised by a doctor.

Influenza

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 2 Reviews
9.2
9.5
Effective influenza remedy
Most Useful Review
Super! The best drug for influenza. It truly works, please 😊

Bruise

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 2 Reviews
9.1
9.5
Stops bruising effectively
Most Useful Review
My favourite Vitamin C! After trying various brands that caused stomach issues, I cautiously bought this one. It’s the only Vitamin C that my body accepts without side effects. I’m thrilled as my previously bloody gums have healed and the bruises from any touch have stopped!

Common Cold

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 53 Reviews
9.1
9.5
Effective cold remedy
Most Useful Review
The quality is excellent. At the onset of a common cold, I take these pills, and they help me recover within a day. Apart from vitamin C, there's also calcium. The tablets are large and sometimes hard to swallow. A dosage of 1000 mg meets my daily needs. My immunity feels robust; I only need two packs per year, and I rarely fall ill. I take them as advised by my doctor.

Autoimmune Disorder

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 3 Reviews
9
9.5
Disease recovery
Most Useful Review
I ordered this thinking I could cut the tablets, but realised they are capsules. When my children brought home a sore, I took 1 capsule with a meal during the day. The illness passed much quicker than before. The non-acidic Vitamin C was a relief, as I previously experienced discomfort with lemon water.

Ulcer

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Excellent
Based on 3 Reviews
9
9.5
Safe for ulcers
Most Useful Review
Vitamin C is essential in my home, especially during cold and flu season. I previously experienced heartburn and stomach pain, but this new form is safe for my gastric mucosa and has not caused any unpleasant effects. It helps condition my iron deficiency anaemia and invigorates me without any issues related to ulcers.

Cancer

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Researches
9
USERS' SCORE
Very Good
Based on 3 Reviews
8.8
9
Vitamin C enhances immune response
Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.
Most Relevant Research
We delved into how vitamin C might influence cancer treatment, focusing on its effects on the immune system. Our findings revealed that vitamin C directly modifies certain proteins, leading to a new type of protein change called vitcylation. This process specifically affects a protein known as STAT1.

By modifying STAT1, vitamin C enhances its ability to signal for immune responses. We found that this modification occurs in both controlled environments and living cells, depending on factors like dosage and acidity. As a result of vitcylation, the action of STAT1 is improved, which activates important immune responses in tumor cells and boosts the expression of molecules that help the immune system recognize and attack cancer cells.

Interestingly, this research sheds light on the potential of vitamin C as a treatment that not only affects cancer directly but also empowers the body’s own defenses. These insights pave the way for new approaches to cancer therapy that leverage the immune system in conjunction with vitamin C.
9.5
Vital for immune system
Most Useful Review
It works! I find this Ester-C absorbs more readily and significantly supports my immune system after cancer. I make sure to keep it stocked at home to combat colds, and I can increase the dosage without upsetting my stomach.

Lung Cancer

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
Strength during illness
Most Useful Review
I have been using this vitamin for seven years. During my battle with pneumonia, I took 2g three times a day, which gave me strength and helped me overcome this serious condition, despite being affected in two lobes of my lungs.

Osteoporosis

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
Improved osteoporosis
Most Useful Review
This has aided my osteoporosis and constipation. Overall, I feel better, though I do take other supplements alongside it.

Rosacea

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
Helps rosacea management
Most Useful Review
An excellent blend of vitamin C with bioflavonoids. I highly recommend considering this product, particularly for those with visible vessels on the face, such as rosacea.

Cold Sores

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 4 Reviews
8.6
9.5
Effective prevention
Most Useful Review
This vitamin C is my staple! I always keep it in my pharmacy. I find it ideal during cold and flu season, especially in its Ester-C form for better absorption. At the first hint of a cold, I take it alongside elderberry syrup, effectively keeping cold sores at bay.

Constipation

SCIENTIFIC SCORE
Most Likely Effective
Based on 1 Researches
8
USERS' SCORE
Very Good
Based on 3 Reviews
8.5
8
Vitamin C's impact on constipation
Feasibility study for a fully decentralized clinical trial in participants with functional constipation symptoms.
Most Relevant Research
We conducted a fully decentralized clinical trial to explore the effects of vitamin C on constipation symptoms. Participants who experienced functional constipation were randomly assigned to receive either Lactobacillus with vitamin C or vitamin C alone over a two-week treatment period. The study allowed us to gather data remotely, which is quite innovative and accessible.

Looking specifically at the results from the group that received vitamin C, we observed that while there was an increase in the frequency of bowel movements compared to the control group, the isolated effect of vitamin C itself wasn't entirely clear. The combination treatment appeared to improve bowel regularity, but it was difficult to determine how much vitamin C contributed independently to these results.

Additionally, we found that about 67% of participants were diligent in tracking their bowel diary entries, which helped ensure the reliability of our findings to an extent. Yet, a significant portion of the records were not kept as scheduled, highlighting potential hurdles in data collection for decentralized trials.

Overall, our observations suggest that while vitamin C, especially when paired with Lactobacillus, may provide some benefits for those struggling with constipation, we should exercise caution before attributing all improvements solely to vitamin C.
8.8
Helps digestion
Most Useful Review
The quality of the product is excellent, with balanced ingredients that improve health due to natural substances. The capsule size is convenient to swallow and has a neutral taste. It aids digestion and alleviates constipation. I recommend purchasing it!

Chronic Cough

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 2 Reviews
8.4
9.5
Prevents infections
Most Useful Review
I fell ill with a chronic cough and sought ways to boost my immunity. The nutritionist recommended vitamin C in this formulation. I found the dosage effective—1000mg daily in the offseason, potentially 2000mg for one month. The results surpassed my expectations. Typically, I catch a cold in autumn, but this time, I remained free of infections, even during cold spells. This first jar success has convinced me to continue using it, despite the hefty price.

Anemia

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 2 Reviews
7.7
8.8
Supports iron absorption
Most Useful Review
Vitamin C is essential in my home first aid kit. During winter, I take 1000-1200 mg daily for prevention of illness. I found a new form of Vitamin C that is gentle on the stomach and includes bioflavonoids, citrus extracts, and rutin. It aids iron absorption, crucial for treating anemia. Although the capsules are large and tasteless, I did not experience any unpleasant side effects. Interestingly, this Vitamin C also seems to invigorate me!

Chronic Fatigue Syndrome

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 8 Reviews
7.6
9.5
Essential vitamin C
Most Useful Review
This vitamin C is a masterpiece! It’s essential for my chronic fatigue syndrome as the body cannot synthesise it adequately. I appreciate the high absorption rate and that it’s gentle on my stomach, allowing me to take it regularly.

Kidney Stones

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Very Good
Based on 3 Reviews
7.2
8.5
Good for stones
Most Useful Review
If you see it available, buy it! This excellent, non-acidic form of vitamin C with bioflavonoids does not irritate the stomach and is well absorbed. It's suitable for those with kidney stones or related issues. I've taken it several times and will continue to do so.

Irritable Bowel Syndrome

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 1 Reviews
6.8
6.8
May alleviate symptoms
Most Useful Review
I purchased this product for various inflamed conditions, including irritable bowel syndrome, and found the effect of Vitamin C to be quite good. However, I experienced digestive discomfort when I consumed it without digestive enzymes, resulting in bloating. The product feels heavier on the stomach than water-soluble vitamins.
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