Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin B12 (as Methylcobalamin from culture of Saccharomyces cerevisiae)
1,000 mcg
41667%
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus plantarum, Lactobacillus bulgaricus] (500 Million CFU)
60 mg
+
Raw Organic Fruit & Vegetable BlendOrganic Apple (fruit), Organic Beet (root), Organic Broccoli (stalk & flower), Organic Carrot (root), Organic Spinach (leaf), Organic Tomato (fruit), Organic Strawberry (fruit), Organic Tart Cherry (fruit), Organic Blackberry (fruit), Organic Green Bell Pepper (fruit), Organic Brussels Sprout (leaf), Organic Blueberry (fruit), Organic Ginger (root), Organic Garlic bulb), Organic Green Onion (bulb), Organic Raspberry (fruit), Organic Parsley (leaf), Organic Cauliflower (flower & stem), Organic Red Cabbage (leaf), Organic Kale (leaf), Organic Cucumber (gourd), Organic Celery (stalk), Organic Asparagus (flower & stem)
20 mg
+
The product is found useful for the following medical conditions
Neuropathy details
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.8
8
We explored the effects of vitamin B12 deficiency on neurological health in elderly patients. In a case study involving two patients, we observed that even with normal B12 levels, symptoms like fatigue and cognitive impairment persisted, especially in those with significant medical histories.
Treatment with hydroxocobalamin injections led to notable improvements in both patients’ cognitive and motor functions. This highlights the importance of recognizing vitamin B12 deficiency in older adults, even when traditional tests suggest adequate levels.
Treatment with hydroxocobalamin injections led to notable improvements in both patients’ cognitive and motor functions. This highlights the importance of recognizing vitamin B12 deficiency in older adults, even when traditional tests suggest adequate levels.
10
Neuropathy resolved
Most Useful Review
8 people found this helpful
Cleared up what I thought was neuropathy in my legs. The tingling in my left thigh was maddening. It wasn't a spinal issue, and the sensation was quite inconvenient. My doctor suggested a daily dose of B-12, which I took. What I believed was neuropathy has completely vanished. I'm extremely pleased. If experiencing similar symptoms, consider a B-12 deficiency.
Depression details
SCIENTIFIC SCORE
Questionable
Based on 21 Researches
6.9
USERS' SCORE
Good
Based on 4 Reviews
8.5
8
We explored the connection between vitamin B levels and depression in older adults over four years. Our study followed nearly 3,850 participants and found that those with low blood levels of vitamin B were significantly more likely to report depressive symptoms. Specifically, individuals with low vitamin B had a 51% higher chance of developing depression compared to those with adequate levels.
However, we did not find any significant link between folate levels and depression. These insights suggest that boosting vitamin B might be a simple, cost-effective way to help improve mental health in older adults.
However, we did not find any significant link between folate levels and depression. These insights suggest that boosting vitamin B might be a simple, cost-effective way to help improve mental health in older adults.
9
Improved mood
Most Useful Review
14 people found this helpful
Amazing B12! This supplement has made a massive difference to my energy levels and mood swings. After taking it alongside a B-complex for just three days, I felt fantastic. I've struggled with severe depression for years, but these two supplements truly work for me. I take them with a fruit smoothie in the morning, and I can’t recommend them enough; simply awesome!
Tinnitus details
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.4
USERS' SCORE
Good
Based on 2 Reviews
8.5
1
We conducted a double-blind clinical trial with 140 patients suffering from idiopathic tinnitus to gauge the effectiveness of vitamin B12. Participants were divided into two groups, one receiving vitamin B12 and the other a placebo over a month.
We evaluated tinnitus severity through questionnaires at multiple intervals. However, our findings revealed that vitamin B12 did not significantly reduce tinnitus severity compared to the placebo.
Ultimately, our study suggests that vitamin B12 may not be a beneficial treatment for tinnitus, as the results showed no noteworthy improvements.
We evaluated tinnitus severity through questionnaires at multiple intervals. However, our findings revealed that vitamin B12 did not significantly reduce tinnitus severity compared to the placebo.
Ultimately, our study suggests that vitamin B12 may not be a beneficial treatment for tinnitus, as the results showed no noteworthy improvements.
7.5
Significant improvement
Most Useful Review
1 people found this helpful
Following online advice about managing tinnitus, I began taking B vitamins, B12, and zinc. After a while, I've noticed a significant improvement in my tinnitus.
Anemia details
SCIENTIFIC SCORE
Moderately Effective
Based on 21 Researches
8.2
USERS' SCORE
Good
Based on 12 Reviews
8.4
9.5
We explored the case of a 23-month-old boy suffering from severe pancytopenia linked to Imerslund-Gräsbeck syndrome, a rare condition caused by an inability to absorb vitamin B12. Upon diagnosis, the boy received vitamin B12 replacement therapy, which effectively addressed his symptoms and improved his health.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
This case highlights the significance of early detection and treatment of IGS to avoid potential neurological damage. It's crucial to recognize this condition, even when neurological symptoms are absent, to provide timely care.
9
Improved haemoglobin
Most Useful Review
5 people found this helpful
The composition is good, and the product is very beneficial. The doctor prescribed this drug for my B-12 deficiency anaemia, which caused broken nails, dizziness, and shortness of breath. After a three-month course, I experienced a significant improvement; my haemoglobin levels normalised, and I no longer have shortness of breath. I highly recommend this! ❤️
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
Relieved muscle pain
Most Useful Review
2 people found this helpful
I purchased it to alleviate muscle pain. Now, on the fourth day of use, I find that after an unfamiliar squat, I no longer feel the bone pain I previously experienced, even when turning over. I recommend it.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.4
USERS' SCORE
Good
Based on 3 Reviews
8.4
0
Vitamin B12 ineffective for CFS
We explored the effectiveness of high-dose vitamin B12 injections on chronic fatigue syndrome (CFS) through two case reports that utilized N of 1 trials. This approach allowed us to make tailored treatment decisions based on individual responses to the therapy.
In one case, we found that high-dose vitamin B12 injections did not yield positive results, leaving the patient without significant relief from their symptoms. Conversely, in another case, we observed that nimodipine proved to be a very effective treatment for that patient’s chronic fatigue.
These findings suggest that while vitamin B12 may not be helpful for everyone suffering from CFS, other treatments like nimodipine can be beneficial. Thus, personalized treatment strategies are key in managing this complex and varied condition.
In one case, we found that high-dose vitamin B12 injections did not yield positive results, leaving the patient without significant relief from their symptoms. Conversely, in another case, we observed that nimodipine proved to be a very effective treatment for that patient’s chronic fatigue.
These findings suggest that while vitamin B12 may not be helpful for everyone suffering from CFS, other treatments like nimodipine can be beneficial. Thus, personalized treatment strategies are key in managing this complex and varied condition.
9
Mood improvement
Most Useful Review
This is the most effective B-12 I've tried! It's gentle on my stomach, and I've noticed a remarkable boost in my mood and energy in under a week. Previously, various other brands either caused discomfort or were ineffective. If I skip my daily pill for about a week, I start to feel fatigued and moody, but this restores me instantly.
Insomnia details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
USERS' SCORE
Good
Based on 3 Reviews
8.3
8
Vitamin B12 promotes sleep in rats
We sought to determine the impact of vitamin B12 (VB12) on sleep patterns in rats, particularly considering its potential benefits for those struggling with insomnia. By giving rats a daily intravenous dose of VB12, we monitored their sleep using polysomnographic recordings over a four-day period.
During our observations, we noticed a significant increase in non-rapid eye movement (NREM) sleep on the second and third days of VB12 administration. Interestingly, REM sleep also showed a notable boost on the second day. The enhancements in sleep were particularly evident during the light period, indicating that vitamin B12 could play a role in promoting sleep at those times.
Additionally, we found that the rats receiving vitamin B12 exhibited serum levels that were 40 times higher than those in control rats, suggesting a robust absorption and impact of the vitamin. Overall, our findings indicate that administering VB12 peripherally does have positive effects on sleep in rats, especially during the light hours.
During our observations, we noticed a significant increase in non-rapid eye movement (NREM) sleep on the second and third days of VB12 administration. Interestingly, REM sleep also showed a notable boost on the second day. The enhancements in sleep were particularly evident during the light period, indicating that vitamin B12 could play a role in promoting sleep at those times.
Additionally, we found that the rats receiving vitamin B12 exhibited serum levels that were 40 times higher than those in control rats, suggesting a robust absorption and impact of the vitamin. Overall, our findings indicate that administering VB12 peripherally does have positive effects on sleep in rats, especially during the light hours.
9
Significant improvement
Most Useful Review
After suffering from insomnia despite taking melatonin, I switched to this B12 upon a friend's suggestion. It has significantly helped reduce stress and improved my sleep quality. Although there are only 30 capsules, each contains 1000 micrograms of B12, and the product is raw and healthy with no fillers. After three months, I take two capsules daily, and I've experienced a 30% improvement in migraines and a notable enhancement in brain concentration.
Back Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 17 Researches
8.3
USERS' SCORE
Good
Based on 6 Reviews
8.1
9
We evaluated the effectiveness of intramuscular vitamin B12 in treating low back pain among 60 patients aged 18 to 65 with mechanical pain lasting at least six months.
In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.
Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
In this double-blind, placebo-controlled study, both groups showed improvement in pain levels. However, those receiving B12 had a more significant reduction in pain and dependence on pain medication compared to the placebo group.
Overall, B12 appears to be a safe option for alleviating low back pain, helping to reduce discomfort and medication use for those without nutritional deficiencies.
9
Muscle relief
Most Useful Review
2 people found this helpful
Muscle pain relief was my goal. After my fourth session with unfamiliar squats, I no longer experienced the painful muscle discomfort I felt previously, even when turning over. I highly recommend this.
Migraine details
SCIENTIFIC SCORE
Questionable
Based on 11 Researches
6.2
USERS' SCORE
Good
Based on 2 Reviews
8
7
We examined the connection between vitamin B12 serum levels and migraine, both chronic and episodic. In our study, we compared two groups: 90 individuals suffering from migraines and 90 healthy participants. We measured the serum vitamin B12 levels of all subjects using a method known as enzyme-linked immunosorbent assay (ELISA).
Our findings showed that those with migraines had notably lower levels of vitamin B12 compared to the healthy control group. Specifically, chronic migraine patients had even lower serum vitamin B12 levels than those with episodic migraines. Additionally, we found a significant negative link between lower vitamin B12 levels and the severity of migraine attacks.
This indicates that individuals with vitamin B12 deficiency may experience more severe migraine symptoms. The results suggest a strong association between low vitamin B12 levels and migraines, pointing to a potential area for further research. We believe that exploring this relationship through interventional studies could offer valuable insights into migraine treatments.
Our findings showed that those with migraines had notably lower levels of vitamin B12 compared to the healthy control group. Specifically, chronic migraine patients had even lower serum vitamin B12 levels than those with episodic migraines. Additionally, we found a significant negative link between lower vitamin B12 levels and the severity of migraine attacks.
This indicates that individuals with vitamin B12 deficiency may experience more severe migraine symptoms. The results suggest a strong association between low vitamin B12 levels and migraines, pointing to a potential area for further research. We believe that exploring this relationship through interventional studies could offer valuable insights into migraine treatments.
7.5
Migraine relief
Most Useful Review
I've noticed an improvement in my migraine headaches; I plan to continue using it.
Heart Attack details
SCIENTIFIC SCORE
Likely Ineffective
Based on 2 Researches
3
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.9
4
Vitamin B12 shows no heart attack benefit
In a recent study, we delved into the role of homocysteine thiolactone, a metabolite linked to heart disease, in predicting the risk of acute myocardial infarction (AMI). Conducted with a sizable group of 2049 patients suspected of having coronary artery disease (CAD), the trial was meticulously designed as a double-blind clinical intervention.
Participants were divided randomly into four distinct groups, receiving a combination of folic acid and other B vitamins or a placebo. Notably, we measured urinary levels of homocysteine thiolactone at different points throughout the study to draw correlations with heart attack incidents.
Our analysis revealed that while the homocysteine thiolactone/creatinine ratio was a significant predictor of AMI risk, there was no observable effect from the vitamin B treatments received by participants. This suggests that vitamin B12, when part of a group of B vitamins, did not independently influence the likelihood of having a heart attack.
Ultimately, we found that higher levels of homocysteine thiolactone correlated with a greater risk of AMI, but the combination of vitamin B treatments did not alter this outcome. This points to the potential of homocysteine thiolactone as an important marker in understanding cardiovascular health.
Participants were divided randomly into four distinct groups, receiving a combination of folic acid and other B vitamins or a placebo. Notably, we measured urinary levels of homocysteine thiolactone at different points throughout the study to draw correlations with heart attack incidents.
Our analysis revealed that while the homocysteine thiolactone/creatinine ratio was a significant predictor of AMI risk, there was no observable effect from the vitamin B treatments received by participants. This suggests that vitamin B12, when part of a group of B vitamins, did not independently influence the likelihood of having a heart attack.
Ultimately, we found that higher levels of homocysteine thiolactone correlated with a greater risk of AMI, but the combination of vitamin B treatments did not alter this outcome. This points to the potential of homocysteine thiolactone as an important marker in understanding cardiovascular health.
4
Joint pain relief
Most Useful Review
Good. I had never tried this brand before, but I’m pleased I did. It alleviated my joint pain and muscle aches. The pills have no taste, and they are tiny, but the ingredients are of high quality. The packaging is excellent, and it provides minerals, hormones, omega, and benefits for inflammation, cholesterol, heart health, and hair.
Chest Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.7
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.7
8
We observed an intriguing case involving a patient suffering from chest pain alongside severe anemia and vitamin B12 deficiency. The patient, a 44-year-old Hispanic woman, presented with escalating non-radiating chest pain, fatigue, and shortness of breath over three weeks. Her lab results showed critical pancytopenia and macrocytosis, raising concerns about a rare condition known as pseudo-thrombotic microangiopathy (TMA), which can occur due to vitamin B12 deficiency.
Initially diagnosed with pseudo-TMA, the patient was undergoing plasmapheresis and steroid treatment. However, once she received daily injections of 1000 micrograms of parenteral vitamin B, her condition began to improve significantly, leading to a resolution of her symptoms, including the chest pain.
This case highlights the importance of considering vitamin B12 deficiency in patients presenting with hemolytic anemia and chest pain. Often misdiagnosed as other conditions, patients may receive unnecessary treatments that delay the correct intervention. It’s vital to recognize the role of sufficient vitamin B12 in addressing specific symptoms like chest pain in such contexts.
Initially diagnosed with pseudo-TMA, the patient was undergoing plasmapheresis and steroid treatment. However, once she received daily injections of 1000 micrograms of parenteral vitamin B, her condition began to improve significantly, leading to a resolution of her symptoms, including the chest pain.
This case highlights the importance of considering vitamin B12 deficiency in patients presenting with hemolytic anemia and chest pain. Often misdiagnosed as other conditions, patients may receive unnecessary treatments that delay the correct intervention. It’s vital to recognize the role of sufficient vitamin B12 in addressing specific symptoms like chest pain in such contexts.
7.5
Reduced pain
Most Useful Review
It’s effective; I have a shoulder problem, and my friend advised me to try taking B12. After about two weeks, I feel better and my chest pain has decreased significantly.
Dizziness details
SCIENTIFIC SCORE
Moderately Effective
Based on 17 Researches
8.4
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.7
9.5
We examined a unique case involving a 28-year-old male who experienced dizziness related to severe anemia from low vitamin B12 levels.
After treatment with daily vitamin B12 injections, his symptoms and lab values significantly improved, indicating a positive response to the treatment.
Despite the rare nature of his condition—seronegative pernicious anemia—the results suggest that B12 can effectively alleviate dizziness stemming from anemia in similar cases.
After treatment with daily vitamin B12 injections, his symptoms and lab values significantly improved, indicating a positive response to the treatment.
Despite the rare nature of his condition—seronegative pernicious anemia—the results suggest that B12 can effectively alleviate dizziness stemming from anemia in similar cases.
9
Improved symptoms
Most Useful Review
5 people found this helpful
The composition is good, and the product is very useful. The doctor prescribed this specific medication for my B-12 deficiency anaemia, which caused my nails to break and dizziness, along with shortness of breath. After a three-month course, I noticed significant improvement; my haemoglobin levels are now normal, and the shortness of breath has disappeared. I highly recommend it ❤️
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.3
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.4
8
We conducted a case-control study to investigate the link between vitamin B12 serum levels and migraine, which affects so many people but lacks a fully understood cause. Our research included 90 individuals experiencing migraines—split into those with chronic migraines and those with episodic migraines—matched against 90 healthy participants.
We measured vitamin B12 serum levels using a reliable testing method and explored how these levels correlated with migraine intensity, as assessed by two measuring scales. Notably, we found that migraine sufferers had significantly lower levels of vitamin B12 compared to those without migraines.
Chronic migraine patients specifically had even lower vitamin B12 levels than their episodic counterparts. Additionally, there was a noteworthy negative correlation; as vitamin B12 levels decreased, the severity of migraine attacks increased. These findings suggest that vitamin B12 deficiency may have an important relationship with migraine experiences, emphasizing the need for further studies to explore this connection in detail.
We measured vitamin B12 serum levels using a reliable testing method and explored how these levels correlated with migraine intensity, as assessed by two measuring scales. Notably, we found that migraine sufferers had significantly lower levels of vitamin B12 compared to those without migraines.
Chronic migraine patients specifically had even lower vitamin B12 levels than their episodic counterparts. Additionally, there was a noteworthy negative correlation; as vitamin B12 levels decreased, the severity of migraine attacks increased. These findings suggest that vitamin B12 deficiency may have an important relationship with migraine experiences, emphasizing the need for further studies to explore this connection in detail.
7.5
Migraine improvement
Most Useful Review
Seems that my migraines are improving; I will continue using it.
