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Supplement Facts
Serving Size: 1 Lozenge
Amount Per Serving
%DV
Vitamin B-12[as Cyanocobalamin, Methylcobalamin (Co-enzyme Form)and Dibencozide (Co-enzyme Form)]
2 mg (2,000 mcg)
83,333%
The product is found useful for the following medical conditions
Back Pain
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
USERS' SCORE
Good
Based on 6 Reviews
8.6
9
Vitamin B12 aids low back pain
Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.
Most Relevant Research
We conducted a thorough investigation to understand whether intramuscular vitamin B12 treatment could effectively relieve low back pain. This study was designed as a double-blind, placebo-controlled trial involving 60 patients aged 18 to 65 who suffered from mechanical low back pain or sciatic neuritis. Each participant had a history of back pain lasting from six months to five years and reported significant pain intensity according to a standard scale.
By comparing two groups—the one receiving vitamin B12 injections and the other receiving a placebo—we focused on measuring changes in pain and disability levels, as well as any changes in paracetamol consumption. What we found was quite impressive. Both groups reported decreases in pain and disability. However, those who received vitamin B12 showed significantly better results compared to the placebo group. The difference was not only notable in terms of pain relief but also in lower dependency on paracetamol for pain management.
Our findings confirm that vitamin B12 can be a safe and effective option for patients with low back pain, particularly for those who don't have any signs of nutritional deficiency. The data suggest that patients experiencing this common ailment could consider discussing vitamin B12 treatment with their healthcare provider as part of their pain management strategy.
By comparing two groups—the one receiving vitamin B12 injections and the other receiving a placebo—we focused on measuring changes in pain and disability levels, as well as any changes in paracetamol consumption. What we found was quite impressive. Both groups reported decreases in pain and disability. However, those who received vitamin B12 showed significantly better results compared to the placebo group. The difference was not only notable in terms of pain relief but also in lower dependency on paracetamol for pain management.
Our findings confirm that vitamin B12 can be a safe and effective option for patients with low back pain, particularly for those who don't have any signs of nutritional deficiency. The data suggest that patients experiencing this common ailment could consider discussing vitamin B12 treatment with their healthcare provider as part of their pain management strategy.
9.5
Disappeared back pain
Most Useful Review
After drinking this supplement, my sciatica pain, which felt like electricity, vanished. The berry taste is delightful, and I recommend it. It's best kept in the fridge as it melts easily once opened.
Chronic Fatigue Syndrome
SCIENTIFIC SCORE
Questionable
Based on 7 Researches
6.4
USERS' SCORE
Good
Based on 17 Reviews
8.6
0
Vitamin B12 ineffective for CFS
N of 1 trials. Managing patients with chronic fatigue syndrome: two case reports.
Most Relevant Research
We explored the effectiveness of high-dose vitamin B12 injections on chronic fatigue syndrome (CFS) through two case reports that utilized N of 1 trials. This approach allowed us to make tailored treatment decisions based on individual responses to the therapy.
In one case, we found that high-dose vitamin B12 injections did not yield positive results, leaving the patient without significant relief from their symptoms. Conversely, in another case, we observed that nimodipine proved to be a very effective treatment for that patient’s chronic fatigue.
These findings suggest that while vitamin B12 may not be helpful for everyone suffering from CFS, other treatments like nimodipine can be beneficial. Thus, personalized treatment strategies are key in managing this complex and varied condition.
In one case, we found that high-dose vitamin B12 injections did not yield positive results, leaving the patient without significant relief from their symptoms. Conversely, in another case, we observed that nimodipine proved to be a very effective treatment for that patient’s chronic fatigue.
These findings suggest that while vitamin B12 may not be helpful for everyone suffering from CFS, other treatments like nimodipine can be beneficial. Thus, personalized treatment strategies are key in managing this complex and varied condition.
8.8
Fatigue alleviated
Most Useful Review
After a week, the constant drowsiness faded, and I felt a renewed desire for vigorous activity. The persistent fatigue and headaches have disappeared.
Tinnitus
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.6
8.8
Strong effect noted
Most Useful Review
I have Meniere's disease and while my symptoms have improved, I still experience strong tinnitus and deafness. Previously, I took 1000 mg before bed, but felt a slight floating sensation. Switching to 2000 mg eliminated that feeling when taken morning and night. The 5000 mg dose, taken once daily, is also effective without causing a floating sensation. I find the 5000 mg version has a strong, pleasing sweet and sour taste, which I enjoy.
Anxiety
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
Vitamin B12 may reduce anxiety
Therapeutic intervention of vitamin B12 in mitigating chronic alcoholism induced alterations in adult zebrafish (): a holistic approach.
Most Relevant Research
We investigated the potential of vitamin B12 to mitigate anxiety in adult zebrafish subjected to chronic alcohol exposure. Our study involved exposing zebrafish to alcohol and then providing them with vitamin B12 to see if it would help reduce anxiety-related behaviors. By using a geotaxis test, we could observe how the fish responded in terms of anxiety in a controlled environment.
The effects were examined alongside oxidative stress and brain health, letting us delve into the biological changes that might occur due to both alcohol and vitamin treatment. The results indicated that chronic alcohol exposure did indeed affect brain function and behavior in the zebrafish. However, we found promising evidence that vitamin B12 operations as a neuroprotective agent, possibly offering relief from the anxiety associated with long-term alcohol use.
Our findings suggest that there may be valuable implications for using vitamin B12 in addressing anxiety related to chronic alcoholism, albeit further studies would be instrumental to fully understand its capabilities and mechanisms.
The effects were examined alongside oxidative stress and brain health, letting us delve into the biological changes that might occur due to both alcohol and vitamin treatment. The results indicated that chronic alcohol exposure did indeed affect brain function and behavior in the zebrafish. However, we found promising evidence that vitamin B12 operations as a neuroprotective agent, possibly offering relief from the anxiety associated with long-term alcohol use.
Our findings suggest that there may be valuable implications for using vitamin B12 in addressing anxiety related to chronic alcoholism, albeit further studies would be instrumental to fully understand its capabilities and mechanisms.
9.5
Helps with anxiety
Most Useful Review
It works! This has helped massively with my anxiety, and I no longer experience mood swings. I recommend it to anyone struggling with depression, as it's cleared my thoughts remarkably.
Anemia
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.8
USERS' SCORE
Good
Based on 12 Reviews
8.5
9
Vitamin B12 effectively treats anemia
An Unusual Case of Hemolytic Anemia: A Case Report.
Most Relevant Research
We observed a compelling case surrounding the impact of vitamin B12 on anemia, particularly in a 62-year-old man facing severe deficiencies due to factors like drug use, hepatitis C, smoking, and alcoholism. Initially, this patient presented with symptoms such as fatigue, fever, and confusion, raising concerns about more critical conditions like thrombotic thrombocytopenic purpura (TTP). Laboratory tests indicated severe pancytopenia and signs of hemolysis, making the situation quite alarming.
However, further investigation revealed that the root cause was a significant deficiency of vitamin B12 coupled with folate. This discovery shifted our focus toward treatment strategies that addressed the underlying deficiency rather than applying unnecessary and invasive procedures like plasmapheresis. Upon administering vitamin B12 injections, we witnessed a refreshing turnaround as the patient's blood counts began to normalize progressively, along with an alleviation of symptoms.
This case emphasizes the necessity for healthcare providers to consider vitamin B12 deficiency when diagnosing patients presenting with hemolytic anemia and thrombocytopenia. By doing so, unnecessary treatments can be avoided, paving the way for a swift recovery through proper vitamin supplementation.
However, further investigation revealed that the root cause was a significant deficiency of vitamin B12 coupled with folate. This discovery shifted our focus toward treatment strategies that addressed the underlying deficiency rather than applying unnecessary and invasive procedures like plasmapheresis. Upon administering vitamin B12 injections, we witnessed a refreshing turnaround as the patient's blood counts began to normalize progressively, along with an alleviation of symptoms.
This case emphasizes the necessity for healthcare providers to consider vitamin B12 deficiency when diagnosing patients presenting with hemolytic anemia and thrombocytopenia. By doing so, unnecessary treatments can be avoided, paving the way for a swift recovery through proper vitamin supplementation.
8.8
Fatigue relief
Most Useful Review
This is perfect for my vegan teenager, as B12 is essential for her health. Taking just one vitamin of 2000 mcg weekly is convenient. Caution is required if taken daily, as rashes may occur. The tablets dissolve under the tongue or can be chewed, making them suitable for children. They help to combat fatigue and anemia, improve memory, and assist in red blood cell formation—no side effects with moderate dosage.
Migraine
SCIENTIFIC SCORE
Questionable
Based on 11 Researches
6.7
USERS' SCORE
Good
Based on 1 Review
8.5
7
Vitamin B12 deficiency and migraines
The correlation between vitamin B12 serum levels and migraine: a case-control study.
Most Relevant Research
We examined the connection between vitamin B12 serum levels and migraine, both chronic and episodic. In our study, we compared two groups: 90 individuals suffering from migraines and 90 healthy participants. We measured the serum vitamin B12 levels of all subjects using a method known as enzyme-linked immunosorbent assay (ELISA).
Our findings showed that those with migraines had notably lower levels of vitamin B12 compared to the healthy control group. Specifically, chronic migraine patients had even lower serum vitamin B12 levels than those with episodic migraines. Additionally, we found a significant negative link between lower vitamin B12 levels and the severity of migraine attacks.
This indicates that individuals with vitamin B12 deficiency may experience more severe migraine symptoms. The results suggest a strong association between low vitamin B12 levels and migraines, pointing to a potential area for further research. We believe that exploring this relationship through interventional studies could offer valuable insights into migraine treatments.
Our findings showed that those with migraines had notably lower levels of vitamin B12 compared to the healthy control group. Specifically, chronic migraine patients had even lower serum vitamin B12 levels than those with episodic migraines. Additionally, we found a significant negative link between lower vitamin B12 levels and the severity of migraine attacks.
This indicates that individuals with vitamin B12 deficiency may experience more severe migraine symptoms. The results suggest a strong association between low vitamin B12 levels and migraines, pointing to a potential area for further research. We believe that exploring this relationship through interventional studies could offer valuable insights into migraine treatments.
8.8
Reduced migraine frequency
Most Useful Review
Great product. I believe this helps my migraines. I used to experience migraines over four times a week, but now it's only 4-8 times a month. My doctor prescribed various herbs, and B112 was one of them. I will stick with them all.
Knee Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.4
9.5
Relieves nerve pain
Most Useful Review
I cannot do without this product. It has greatly alleviated my neck nerve pain and provided me with energy. The quality is high, the quantity is ample, and it has a pleasant, sweet taste. It is high-quality and beneficial for women.
Autoimmune Disorder
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.8
USERS' SCORE
Good
Based on 3 Reviews
8.2
9
Pernicious anemia treatment effectiveness
Rural health challenges in Western Uganda: pernicious anemia masquerading as recurrent lower limb weakness-a case report.
Most Relevant Research
We explored the impact of vitamin B12 treatment on individuals suffering from pernicious anemia, an autoimmune disorder that affects the body’s ability to absorb this essential vitamin. In a recent case report, a 51-year-old man from Uganda presented with lower limb weakness, which had returned after an earlier bout of vitamin B12 deficiency.
Upon investigation, he was diagnosed with pernicious anemia, a condition that can cause a range of symptoms due to the body’s inability to produce intrinsic factor, crucial for vitamin B12 absorption. After starting parenteral methylcobalamin therapy, we observed significant improvements in his symptoms, highlighting how effective vitamin B12 can be in managing this disorder.
This case emphasizes the need for awareness and timely diagnosis of vitamin B12 deficiency among healthcare providers, especially in resource-limited settings. Such proactive management can lead to recovery and improved quality of life for those affected.
Upon investigation, he was diagnosed with pernicious anemia, a condition that can cause a range of symptoms due to the body’s inability to produce intrinsic factor, crucial for vitamin B12 absorption. After starting parenteral methylcobalamin therapy, we observed significant improvements in his symptoms, highlighting how effective vitamin B12 can be in managing this disorder.
This case emphasizes the need for awareness and timely diagnosis of vitamin B12 deficiency among healthcare providers, especially in resource-limited settings. Such proactive management can lead to recovery and improved quality of life for those affected.
9.5
Effective for pain
Most Useful Review
This vitamin is crucial for me. I noticed an improvement in my tremor, which disappeared after taking it daily. I got it for my husband, as he had nerve pain in his fingers, and after a three-month course, the inflammation significantly reduced. The product has no smell or strange taste, and it doesn’t upset the stomach. I recommend it for autoimmune disorder-related nerve inflammation; effects are felt within the first week.
