Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Blend of Probiotic Bacteria:Lactobacillus acidophilus (La-14),Bifidobacterium lactis (Bl-04),Bifidobacterium longum (Bl-05)
8 Billion CFU
*

The product is found useful for the following medical conditions

Heartburn details

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 5 Reviews
8.8
Our research aimed to understand how a specific symbiotic gel, containing Lactobacillus acidophilus, affects gastrointestinal symptoms, including heartburn, in hemodialysis patients.

We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.

Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
10
Heartburn gone
Most Useful Review
9 people found this helpful
Heartburn be gone! My husband has had awful heartburn for years and after 2 weeks of taking this, it is gone. I take it when on medication and no longer experience an upset stomach.

Reflux details

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.8
USERS' SCORE
Good
Based on 2 Reviews
8.7
We explored the effects of Lactobacillus species on bile-induced DNA damage in esophageal cells, which occurs during gastroesophageal reflux disease (GERD). By exposing these bacteria to a bile-rich environment, we found they could survive and interact beneficially with injured cells.

Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.
10
Reflux relief ensured
Most Useful Review
16 people found this helpful
Fixed my acid reflux. After a couple of years on doctor-prescribed medication with no effect, I decided to try something new and found that NOW acidophilus eliminated what I suspected was an intestinal candida yeast problem responsible for my distressing acid reflux. Within two days of starting the treatment, my reflux disappeared, and I felt better than ever! That was about a year ago.

Indigestion details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 5 Reviews
8.6
This study looked into how a specific synbiotic product, which includes Lactobacillus acidophilus along with other probiotics and fructooligosaccharides, affects digestive health among healthy adults. In a randomized, double-blind, placebo-controlled design, we monitored 36 participants—20 women and 16 men aged between 25 and 45 years—over six weeks.

Participants received either the synbiotic supplement or a placebo, taking three tablets daily. We gathered information on gastrointestinal symptoms and bowel habits through a self-administered questionnaire, focusing especially on those who experienced digestive disturbances like mild dyspepsia or bloating.

The results were promising; those who took the synbiotic product reported significant improvements in their overall gastrointestinal well-being and bowel movements. Interestingly, we also noted a reduction in a specific immune marker, L-selectin, in the synbiotic group, which could indicate a favorable shift in their immune profile. However, while the improvements in gut health were noteworthy, none of the other immunological parameters were significantly altered.

In summary, this study suggests that including Lactobacillus acidophilus as part of a synbiotic supplement can lead to better digestive comfort and may influence immune-related markers positively. However, pinpointing the exact effect of this specific strain on indigestion alone is challenging, given the multi-strain nature of the synbiotic treatment.
9
Less indigestion
Most Useful Review
41 people found this helpful
Excellent product. As a pharmacist, I have significant experience with both prescription and over-the-counter medications. Based on quantity, price, and effectiveness, this is one of the best probiotics available. I noticed a positive difference in the overall health of my gastrointestinal system within two days of starting this product. I experience less indigestion, bloating, diarrhoea, and constipation. There are other products that are just as effective, but they cost significantly more for less product.

Rash details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Effective for rashes
Most Useful Review
A good product. A worthy replacement for Linex, Fertal, and Normobact. My teenage daughter takes it periodically, and the rashes on her face disappear while her stool normalises.

Eczema details

SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.4
USERS' SCORE
Good
Based on 4 Reviews
8.5
We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.

Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.
9
Eczema improvement
Most Useful Review
11 people found this helpful
I have suffered from hand eczema for about a year. After starting biotin therapy alongside vitamin C and an intestinal regulator, my eczema ceased within 10 days, and my skin became more vibrant. I am grateful I discovered this treatment.

Pelvic Pain details

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5.5
USERS' SCORE
Good
Based on 4 Reviews
8.5
We examined the urinary microbiome of women with interstitial cystitis and found it less diverse and containing fewer Lactobacillus acidophilus compared to a control group.

This lack of Lactobacillus was linked to more severe symptoms and poor quality of life. While we noted some associations between higher inflammatory markers and the severity of symptoms, we didn’t see a clear causal relationship.

Essentially, we’re still unsure if the presence of Lactobacillus can effectively reduce pelvic pain in this context.
9
Pelvic pain relief
Most Useful Review
15 people found this helpful
Great tool! I had issues with my intestines for several years, suffering from rejections, abdominal distension, and pelvic pain. Nothing really helped. After taking this product for about 3-4 months, everything improved! My attacks now occur very rarely and pass quickly. Praise the Lord and thanks to the manufacturer!

Pneumonia details

SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
We explored how the probiotic Bifidobacterium longum 5(1A) can affect pneumonia caused by Klebsiella pneumoniae in mice. Our study showed that this treatment led to a quicker resolution of lung inflammation and significantly reduced the bacterial load, ultimately saving 100% of the mice from death.

This protective effect was linked to the activation of the Toll-like receptor signaling pathway. In particular, B. longum 5(1A) helped balance the body's inflammatory response, promoting a faster recovery in the lungs. Overall, our findings suggest that this probiotic could play a beneficial role in enhancing lung health during infections.
9
Effective recovery
Most Useful Review
2 people found this helpful
An excellent tool! My brother fell seriously ill with pneumonia this winter and had difficulty recovering. After taking this supplement, he began to improve, especially after the antibiotics affected his intestinal microflora. I definitely recommend it! We frequently use dietary supplements from NOW and have never been disappointed.

Sleep Apnea details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.5
9
Decreased discomfort
Most Useful Review
33 people found this helpful
I was frustrated by my husband's farts, which were so strong it was like fruit and painful to sleep with me. After trying various remedies, this supplement noticeably reduced both the frequency and smell, allowing me to sleep peacefully again. I'm incredibly grateful! (^^)

Yeast Infection details

SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.1
USERS' SCORE
Good
Based on 7 Reviews
8.5
We explored how Lactobacillus acidophilus ATCC 4356 impacts yeast infections caused by Candida albicans. The study used both in vitro and in vivo models, with tests on biofilm formation and filamentation in lab settings and survival analysis in Galleria mellonella larvae.

Our findings revealed that L. acidophilus was effective in inhibiting C. albicans biofilm and filament formation in vitro. Additionally, the injections into infected larvae significantly improved their survival rates and reduced yeast counts compared to a control group. Overall, L. acidophilus demonstrated promising protective effects against yeast infections.
9
Stops infections
Most Useful Review
6 people found this helpful
NOW BRAND IS THE BEST. This acidophilus brand is the ONLY one that alleviates yeast infections. As someone who consumes a lot of sugar and is prone to yeast infections, I have tried every brand available. This one is truly exceptional.

Bacterial Infection details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 3 Reviews
8.4
We explored the effects of Lactobacillus acidophilus fermentation products on weanling pigs that were challenged with a harmful strain of bacteria known as enterotoxigenic F4 Escherichia coli (F4-ETEC). To better understand this, we conducted a detailed study involving eighty pigs, which were divided into five groups based on different diets. This included a control diet, as well as diets supplemented with various fermentation products and zinc oxide.

After inoculating the pigs with F4-ETEC to simulate infection, we observed significant changes in the pigs’ fecal microbiome when they were given a combination of Lactobacillus and Saccharomyces products. These changes in the microbiome were previously linked to better growth performance and overall health in young pigs.

Interestingly, the pigs receiving both Lactobacillus acidophilus and Saccharomyces cerevisiae products showed an increase in final live weight. This suggests that using these postbiotics could help manage performance issues associated with ETEC without needing to eliminate the bacteria entirely from the pigs' environment. Therefore, while Lactobacillus acidophilus was not the sole hero in this study, its combined use proved beneficial in combatting the negative effects of this bacterial challenge.
9
Regulates stool consistency
Most Useful Review
I expected this to be effective due to its high bacterial content. I have always struggled with loose stools and often felt unwell. After drinking this, my stools have normalised and I feel good. I intend to keep using it for a while.

Swollen Lymph Nodes details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.4
9
Improved dog digestion
Most Useful Review
11 people found this helpful
Stomach bloating and gas have drastically reduced! I have been using Acidophilus against candida. This Now product has Lactobacillus acidophilus and bifidobacteria. I noticed my Labrador's stomach, which used to bloat after meals, is now much better, and the odour has lessened significantly. This had great results for my dog, but self-responsibility is essential since it’s intended for humans.

Allergies details

SCIENTIFIC SCORE
Moderately Effective
Based on 55 Researches
8.2
USERS' SCORE
Good
Based on 6 Reviews
8.3
We investigated the impact of a probiotic ice cream containing engineered bacteria on pollen allergies in mice. After sensitizing the mice, we treated them with this unique ice cream for four weeks. The results were promising! The ice cream significantly lowered serum IgE levels, which are linked to allergic reactions. Additionally, beneficial cytokines increased while the levels of a harmful cytokine decreased. Overall, our findings suggest that this probiotic ice cream could improve allergy responses, particularly with Th1 and Treg involvement.
7.5
Skin and gut health
Most Useful Review
12 people found this helpful
My persistent diarrhoea and constipation have ceased, and my skin has improved markedly. This product seems to have alleviated my allergies too. I believe that maintaining a healthy gut is crucial to overall wellbeing, and this supplement is recommended even for those in good health.

Candidiasis details

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 15 Reviews
8.3
We set out to explore how lactobacillus acidophilus, specifically strain B-2178, impacts vulvovaginal candidiasis (VVC) in female rats. By dividing our study subjects into five groups, we included controls and examined the effects of different treatments.

In particular, we analyzed the immune response of the vaginal tissue after intravaginal inoculation to establish VVC. The rats treated with strain B-2178 showed a promising ability to maintain an immune-tolerant state in the vaginal epithelium. Through this action, it seemed capable of reducing uncontrolled inflammation, which is often a challenge during candidiasis.

Although our findings suggest that B-2178 may be beneficial in treating VVC, it's important to note that the overall focus was broader and did not isolate lactobacillus acidophilus alone. This makes it difficult to pinpoint the specific advantages of this particular strain compared to others.

Ultimately, it appears that while B-2178 exhibits potential, more targeted research is required to evaluate its effectiveness in isolating and addressing candidiasis comprehensively.
9
Itching resolved
Most Useful Review
9 people found this helpful
My immune system has improved since I began consistently using this product after struggling with vaginal Candidiasis for two years. After two years of persistent use, I noticed the itching had vanished, and I finally felt relief! Though everyone's experience will differ, I believe this product helped significantly based on my continuous use. If you're experiencing similar symptoms, I suggest giving it a try, as it may take time, but relief is possible.

Celiac details

SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.4
USERS' SCORE
Good
Based on 3 Reviews
8.3
We examined a promising new probiotic preparation designed to break down gluten and assist people with celiac disease. Our study included a randomized double-blind placebo-controlled trial with 70 volunteers over a 42-day period, where participants consumed increasing amounts of gluten following a gluten-free diet.

Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.
9
Restored gut health
Most Useful Review
3 people found this helpful
An excellent remedy for sensitive tummies, it is soy-free, gluten-free, and dairy-free—everything needed for a moody digestive system. After my child experienced digestive issues due to long courses of antibiotics, this product helped restore normal stool consistency and digestion. The results were much more effective and lasting compared to previous remedies from Russia. We will continue to purchase this for preventive care.

Diarrhea details

SCIENTIFIC SCORE
Moderately Effective
Based on 56 Researches
8.2
USERS' SCORE
Good
Based on 35 Reviews
8.3
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.

Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.

Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.

This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
9
Effective for diarrhea
Most Useful Review
41 people found this helpful
This product is excellent. As a pharmacist, I recognise its effectiveness for treating diarrhoea. I felt a positive change in my gastrointestinal health within two days. I experienced less indigestion, bloating, and constipation. While there are other effective products, they are often much pricier for less product.

Food Poisoning details

SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.6
USERS' SCORE
Good
Based on 5 Reviews
8.3
We aimed to find out if probiotic supplements like lactobacillus acidophilus could help counteract the negative effects of iron fortification, which has been linked to increased diarrhea and food poisoning among children.

In our study with weaning mice, we discovered that high iron diets led to more severe symptoms when infected with Salmonella.

However, when we added lactobacillus acidophilus beforehand, the mice showed less severe symptoms and better intestinal health.

This suggests that probiotics can really help protect gut health against the adverse effects of iron supplements during foodborne infections.
7.5
Thrush improvement
Most Useful Review
6 people found this helpful
Without an appendix? This probiotic is ideal for you! It helps replenish useful bacteria. My friend had thrush and after taking this for a week, it cleared up.

Back Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.2
9
Intestinal problem solution
Most Useful Review
15 people found this helpful
Great tool! For several years, I struggled with severe intestinal issues, including abdominal distention and strong pains, which nothing seemed to remedy. After taking this product for 3-4 months, all my problems ceased! My attacks are now very rare and pass quickly. I am immensely grateful to the manufacturer.

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6
USERS' SCORE
Good
Based on 6 Reviews
8.2
We explored the effects of Lactobacillus acidophilus, both free and in floating beads, as a possible treatment for chronic fatigue syndrome in a rat model. The study involved inducing fatigue through a forced swim test and then administering the probiotics over the last week of the experiment.

Remarkably, we found that both forms of Lactobacillus led to significant reductions in fatigue-like behaviors and improved biomarkers associated with stress. This indicates that lactobacilli may serve as a beneficial option for alleviating symptoms of chronic fatigue syndrome.
9
Stabilised condition
Most Useful Review
1 people found this helpful
For five years, I’ve taken this daily, and it has greatly stabilised my chronic fatigue syndrome and irritable bowel syndrome. I now have regular bowel movements after breakfast and don’t feel the need to go throughout the day, and I've been healthier, not catching colds for years. This product suits me best among others I've tried.

Cold details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.2
10
No winter illnesses
Most Useful Review
I'm a fan! I went through a whole cold European winter without falling ill thanks to this probiotic. I've had great results with it; it's excellent!

Acne details

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 5 Reviews
8.1
We examined the antibacterial and anti-inflammatory effects of Bifidobacterium in relation to acne. Our findings showed that certain strains, including Bifidobacterium longum, significantly lowered the viability of acne-causing bacteria. We also found that these strains reduced harmful inflammatory markers in cell tests.

Ultimately, while Bifidobacterium longum showed promise in reducing acne-related bacteria, the study suggests Bifidobacterium adolescentis may be more effective in tackling the problem.
9
Effective for acne
Most Useful Review
4 people found this helpful
Great product! Normally, when taking supplements, you often don't notice any changes, but this one is different. An acupuncturist suggested that something aiding digestion would also help my acne. That's when I discovered this product, and it genuinely works! It's also easy to order and arrives quickly in a Styrofoam box with an ice pack, ensuring it stays chilled.

Common Cold details

SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.3
USERS' SCORE
Good
Based on 6 Reviews
8.1
We investigated how consuming Qingrun yogurt, which contains the probiotic Bifidobacterium lactis, affects common colds among adults living in hazy areas. In a clinical trial with 136 participants, those who enjoyed the probiotic yogurt daily experienced fewer colds and reported milder symptoms compared to those who consumed regular yogurt.

Remarkably, it even shortened the duration and intensity of respiratory infections. The findings suggest that incorporating probiotic yogurt into our diets could be a beneficial strategy to help combat upper respiratory infections.
9
Stable condition
Most Useful Review
1 people found this helpful
I have been taking this every day for five years due to my weak stomach and irritable bowel. Since starting it, my condition has stabilised, and I rarely catch a common cold, feeling much healthier overall.

Bloating details

SCIENTIFIC SCORE
Possibly Effective
Based on 34 Researches
7.6
USERS' SCORE
Good
Based on 30 Reviews
8
We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.

Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
9
Reduced bloating
Most Useful Review
57 people found this helpful
Excellent flora for digestion! I took two capsules at night along with other supplements. After about two weeks, I noticed an improvement in my wellbeing. This product restores the natural microbial balance in the intestine, regulates the gastrointestinal tract, and helps maintain the growth of beneficial microorganisms. It can aid those who struggle with dairy. I’m definitely buying this again!

Irritable Bowel Syndrome details

SCIENTIFIC SCORE
Possibly Effective
Based on 41 Researches
7.7
USERS' SCORE
Good
Based on 9 Reviews
8
A randomized, double-blind, placebo-controlled trial exploring CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) revealed promising results for diarrhea-predominant irritable bowel syndrome (IBS-D).

We found that after 12 weeks, both ES1 and HT-ES1 significantly reduced symptom severity compared to a placebo, as shown by lower IBS-Symptom Severity Scale scores.

Other improvements included better stool consistency and quality of life. This study marks a breakthrough with the first positive findings for a probiotic or postbiotic from this strain specifically for IBS-D patients.
9
Bowel issues resolved
Most Useful Review
1 people found this helpful
This is a great product; many of my bowel issues disappeared immediately upon using it.

Autoimmune Disorder details

SCIENTIFIC SCORE
Moderately Effective
Based on 39 Researches
8
USERS' SCORE
Moderately Good
Based on 12 Reviews
7.7
We investigated the potential of Lactococcus lactis, a safe bacterial strain, to deliver protective proteins for preventing type 1 diabetes (T1DM) in NOD mice. Our study used two specially engineered strains that expressed a specific protein.

We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.
9
Restored digestion
Most Useful Review
8 people found this helpful
After suffering from an autoimmune disorder, my mother experienced severe dysbiosis post-covid. Pharmaceuticals failed to help, but these capsules significantly restored her digestive health from the first days of use.

Constipation details

SCIENTIFIC SCORE
Possibly Effective
Based on 48 Researches
7.7
USERS' SCORE
Moderately Good
Based on 74 Reviews
7.3
We explored the impact of Bifidobacterium lactis BLa80 on constipation using mice that were induced with functional constipation through loperamide treatment. In our study, we compared BLa80 to a blank group and a positive control.

The results indicated that BLa80 improved intestinal movement, increased fecal moisture, and balanced gut bacteria. It also helped regulate important gut hormones. Overall, BLa80 shows promise as a potential new option for relieving constipation in functional foods.
9
Positive GI health
Most Useful Review
41 people found this helpful
Excellent product! As a pharmacist, I find this one of the best probiotics available. Within two days of taking it, my gastrointestinal health improved significantly. I experienced reduced indigestion, bloating, and both constipation and diarrhoea. There are other effective products, but they are often pricier with less quantity.
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