NOW Supplements 8 Billion Acidophilus &amp; Bifidus

Probiotics repair DNA in GERD

Based on 6 Researches

Bernard JN, Chinnaiyan V, Almeda J, Catala-Valentin A, Andl CD. sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux Disease. Antioxidants (Basel). 2023;12. doi:10.3390/antiox12071314

We explored the effects of Lactobacillus species on bile-induced DNA damage in esophageal cells, which occurs during gastroesophageal reflux disease (GERD). By exposing these bacteria to a bile-rich environment, we found they could survive and interact beneficially with injured cells.

Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.

Reflux relief ensured

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16 people found this helpful

Fixed my acid reflux. After a couple of years on doctor-prescribed medication with no effect, I decided to try something new and found that NOW acidophilus eliminated what I suspected was an intestinal candida yeast problem responsible for my distressing acid reflux. Within two days of starting the treatment, my reflux disappeared, and I felt better than ever! That was about a year ago.

Updated: Apr 2025

Indigestion details

Probiotics may alleviate indigestion

Based on 14 Researches

Majeed M, Nagabhushanam K, Paulose S, Arumugam S, Mundkur L. The effects of Bacillus coagulans MTCC 5856 on functional gas and bloating in adults: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2023;102:e33109. doi:10.1097/MD.0000000000033109

We examined the effects of Bacillus coagulans MTCC 5856, a type of probiotic, on functional gas and bloating in adults. In a well-structured, double-blind study with 70 participants, those taking the probiotics saw a significant reduction in indigestion symptoms compared to the placebo group.

Although the probiotic group had notable improvements in their symptom scores, the placebo group also experienced some changes. Overall, Bacillus coagulans shows promise as a helpful supplement for those experiencing bothersome bloating and gas.

Less indigestion

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41 people found this helpful

Excellent product. As a pharmacist, I have significant experience with both prescription and over-the-counter medications. Based on quantity, price, and effectiveness, this is one of the best probiotics available. I noticed a positive difference in the overall health of my gastrointestinal system within two days of starting this product. I experience less indigestion, bloating, diarrhoea, and constipation. There are other products that are just as effective, but they cost significantly more for less product.

Updated: Mar 2026

Rash details

A good product. A worthy replacement for Linex, Fertal, and Normobact. My teenage daughter takes it periodically, and the rashes on her face disappear while her stool normalises.

Updated: Apr 2025

Eczema details

Lactobacillus acidophilus helps eczema

Based on 19 Researches

Kim WK, Jang YJ, Park S, Min SG, Kwon H, et al. Lactobacillus acidophilus KBL409 Ameliorates Atopic Dermatitis in a Mouse Model. J Microbiol. 2024;62:91. doi:10.1007/s12275-024-00104-5

We explored the potential of Lactobacillus acidophilus KBL409 in addressing atopic dermatitis, a common form of eczema. By using a mouse model induced by house dust mites, we found that administering this probiotic led to significantly lower dermatitis scores and less immune cell infiltration in the skin.

Additionally, L. acidophilus KBL409 reduced serum immunoglobulin E and influenced various cytokines linked to inflammation. It also positively affected gut microbiota and concentrations of beneficial compounds, hinting at a broader impact on our immune responses. Overall, our findings suggest that L. acidophilus KBL409 may be a promising probiotic for eczema management.

Eczema improvement

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11 people found this helpful

I have suffered from hand eczema for about a year. After starting biotin therapy alongside vitamin C and an intestinal regulator, my eczema ceased within 10 days, and my skin became more vibrant. I am grateful I discovered this treatment.

Updated: Mar 2026

Pelvic Pain details

Lactobacillus association with pelvic pain

Questionable

Based on 2 Researches

Abernethy MG, Rosenfeld A, White JR, Mueller MG, Lewicky-Gaupp C, et al. Urinary Microbiome and Cytokine Levels in Women With Interstitial Cystitis. Obstet Gynecol. 2017;129:500. doi:10.1097/AOG.0000000000001892

We examined the urinary microbiome of women with interstitial cystitis and found it less diverse and containing fewer Lactobacillus acidophilus compared to a control group.

This lack of Lactobacillus was linked to more severe symptoms and poor quality of life. While we noted some associations between higher inflammatory markers and the severity of symptoms, we didn’t see a clear causal relationship.

Essentially, we’re still unsure if the presence of Lactobacillus can effectively reduce pelvic pain in this context.

Pelvic pain relief

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15 people found this helpful

Great tool! I had issues with my intestines for several years, suffering from rejections, abdominal distension, and pelvic pain. Nothing really helped. After taking this product for about 3-4 months, everything improved! My attacks now occur very rarely and pass quickly. Praise the Lord and thanks to the manufacturer!

Updated: Apr 2025

Pneumonia details

Bifidobacterium longum protects against pneumonia

Based on 12 Researches

Vieira AT, Rocha VM, Tavares L, Garcia CC, Teixeira MM, et al. Control of Klebsiella pneumoniae pulmonary infection and immunomodulation by oral treatment with the commensal probiotic Bifidobacterium longum 5(1A). Microbes Infect. 2016;18:180. doi:10.1016/j.micinf.2015.10.008

We explored how the probiotic Bifidobacterium longum 5(1A) can affect pneumonia caused by Klebsiella pneumoniae in mice. Our study showed that this treatment led to a quicker resolution of lung inflammation and significantly reduced the bacterial load, ultimately saving 100% of the mice from death.

This protective effect was linked to the activation of the Toll-like receptor signaling pathway. In particular, B. longum 5(1A) helped balance the body's inflammatory response, promoting a faster recovery in the lungs. Overall, our findings suggest that this probiotic could play a beneficial role in enhancing lung health during infections.

Effective recovery

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2 people found this helpful

An excellent tool! My brother fell seriously ill with pneumonia this winter and had difficulty recovering. After taking this supplement, he began to improve, especially after the antibiotics affected his intestinal microflora. I definitely recommend it! We frequently use dietary supplements from NOW and have never been disappointed.

Updated: Mar 2026

Sleep Apnea details

33 people found this helpful

I was frustrated by my husband's farts, which were so strong it was like fruit and painful to sleep with me. After trying various remedies, this supplement noticeably reduced both the frequency and smell, allowing me to sleep peacefully again. I'm incredibly grateful! (^^)

Updated: Mar 2026

Yeast Infection details

L. acidophilus inhibits C. albicans

Based on 12 Researches

Vilela SF, Barbosa JO, Rossoni RD, Santos JD, Prata MC, et al. Lactobacillus acidophilus ATCC 4356 inhibits biofilm formation by C. albicans and attenuates the experimental candidiasis in Galleria mellonella. Virulence. 2015;6:29. doi:10.4161/21505594.2014.981486

We explored how Lactobacillus acidophilus ATCC 4356 impacts yeast infections caused by Candida albicans. The study used both in vitro and in vivo models, with tests on biofilm formation and filamentation in lab settings and survival analysis in Galleria mellonella larvae.

Our findings revealed that L. acidophilus was effective in inhibiting C. albicans biofilm and filament formation in vitro. Additionally, the injections into infected larvae significantly improved their survival rates and reduced yeast counts compared to a control group. Overall, L. acidophilus demonstrated promising protective effects against yeast infections.

Stops infections

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6 people found this helpful

NOW BRAND IS THE BEST. This acidophilus brand is the ONLY one that alleviates yeast infections. As someone who consumes a lot of sugar and is prone to yeast infections, I have tried every brand available. This one is truly exceptional.

Updated: Mar 2026

Allergies details

Probiotic ice cream reduces allergies

Based on 55 Researches

Vasiee A, Falah F, Sankian M, Tabatabaei-Yazdi F, Mortazavi SA. Oral Immunotherapy Using Probiotic Ice Cream Containing Recombinant Food-Grade Which Inhibited Allergic Responses in a BALB/c Mouse Model. J Immunol Res. 2020;2020:2635230. doi:10.1155/2020/2635230

We investigated the impact of a probiotic ice cream containing engineered bacteria on pollen allergies in mice. After sensitizing the mice, we treated them with this unique ice cream for four weeks. The results were promising! The ice cream significantly lowered serum IgE levels, which are linked to allergic reactions. Additionally, beneficial cytokines increased while the levels of a harmful cytokine decreased. Overall, our findings suggest that this probiotic ice cream could improve allergy responses, particularly with Th1 and Treg involvement.

Allergy improvement

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10 people found this helpful

I have a wheat allergy and began taking several supplements for my leaky gut. After three months, my wheat allergy vanished! I'm thrilled to eat anything now. While I cannot ascertain the effect of this product alone, my gut health has definitely improved. I store it in the fridge and consume it before bed, and the size is easy to drink.

Updated: Mar 2026

Bacterial Infection details

Lactobacillus aids pigs' health

Cherrington T, Jordan D, Pluske J, Mansfield J, Lugsomya K, et al. Lactobacillus and Saccharomyces fermentation products impact performance and the fecal microbiome in weanling pigs inoculated with enterotoxigenic Escherichia coli. J Anim Sci. 2025;103. doi:10.1093/jas/skae394

We explored the effects of Lactobacillus acidophilus fermentation products on weanling pigs that were challenged with a harmful strain of bacteria known as enterotoxigenic F4 Escherichia coli (F4-ETEC). To better understand this, we conducted a detailed study involving eighty pigs, which were divided into five groups based on different diets. This included a control diet, as well as diets supplemented with various fermentation products and zinc oxide.

After inoculating the pigs with F4-ETEC to simulate infection, we observed significant changes in the pigs’ fecal microbiome when they were given a combination of Lactobacillus and Saccharomyces products. These changes in the microbiome were previously linked to better growth performance and overall health in young pigs.

Interestingly, the pigs receiving both Lactobacillus acidophilus and Saccharomyces cerevisiae products showed an increase in final live weight. This suggests that using these postbiotics could help manage performance issues associated with ETEC without needing to eliminate the bacteria entirely from the pigs' environment. Therefore, while Lactobacillus acidophilus was not the sole hero in this study, its combined use proved beneficial in combatting the negative effects of this bacterial challenge.

Regulates stool consistency

Most Useful Review

I expected this to be effective due to its high bacterial content. I have always struggled with loose stools and often felt unwell. After drinking this, my stools have normalised and I feel good. I intend to keep using it for a while.

Updated: Apr 2025

Food Poisoning details

Lactobacillus aids gut health during infections

Based on 12 Researches

Lin F, Wu H, Zeng M, Yu G, Dong S, et al. Probiotic/prebiotic correction for adverse effects of iron fortification on intestinal resistance to Salmonella infection in weaning mice. Food Funct. 2018;9:1070. doi:10.1039/c7fo00990a

We aimed to find out if probiotic supplements like lactobacillus acidophilus could help counteract the negative effects of iron fortification, which has been linked to increased diarrhea and food poisoning among children.

In our study with weaning mice, we discovered that high iron diets led to more severe symptoms when infected with Salmonella.

However, when we added lactobacillus acidophilus beforehand, the mice showed less severe symptoms and better intestinal health.

This suggests that probiotics can really help protect gut health against the adverse effects of iron supplements during foodborne infections.

Effective for poisoning

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3 people found this helpful

I hesitated before buying, but this really works for food poisoning and mild digestive upset. I now recommend having it in your medicine cabinet.

Updated: Mar 2026

Autoimmune Disorder details

Lactococcus lactis shows promise for T1DM

Based on 39 Researches

Liu KF, Liu XR, Li GL, Lu SP, Jin L, et al. Oral administration of Lactococcus lactis-expressing heat shock protein 65 and tandemly repeated IA2P2 prevents type 1 diabetes in NOD mice. Immunol Lett. 2016;174:28. doi:10.1016/j.imlet.2016.04.008

We investigated the potential of Lactococcus lactis, a safe bacterial strain, to deliver protective proteins for preventing type 1 diabetes (T1DM) in NOD mice. Our study used two specially engineered strains that expressed a specific protein.

We found that oral administration of these Lactococcus lactis strains helped stop high blood sugar, enhanced glucose tolerance, and reduced inflammation in the pancreas. This occurred by suppressing certain auto-reactive T cells and encouraging healthy immune responses. Our results suggest that this method could effectively help prevent T1DM in these mice.

Balanced flora

Most Useful Review

Probiotics are essential for maintaining my oral and intestinal flora balance, crucial for managing my autoimmune disorder. When I run out, I can certainly tell the difference.

Updated: Mar 2026

Candidiasis details

Lactobacillus impact on candidiasis

Likely Very Effective

ElFeky DS, Awad AR, Shamseldeen AM, Mowafy HL, Hosny SA. Comparing the therapeutic potentials of vs. against vulvovaginal candidiasis in female rats: an study. Front Microbiol. 2023;14:1222503. doi:10.3389/fmicb.2023.1222503

We set out to explore how lactobacillus acidophilus, specifically strain B-2178, impacts vulvovaginal candidiasis (VVC) in female rats. By dividing our study subjects into five groups, we included controls and examined the effects of different treatments.

In particular, we analyzed the immune response of the vaginal tissue after intravaginal inoculation to establish VVC. The rats treated with strain B-2178 showed a promising ability to maintain an immune-tolerant state in the vaginal epithelium. Through this action, it seemed capable of reducing uncontrolled inflammation, which is often a challenge during candidiasis.

Although our findings suggest that B-2178 may be beneficial in treating VVC, it's important to note that the overall focus was broader and did not isolate lactobacillus acidophilus alone. This makes it difficult to pinpoint the specific advantages of this particular strain compared to others.

Ultimately, it appears that while B-2178 exhibits potential, more targeted research is required to evaluate its effectiveness in isolating and addressing candidiasis comprehensively.

Itching resolved

Most Useful Review

9 people found this helpful

My immune system has improved since I began consistently using this product after struggling with vaginal Candidiasis for two years. After two years of persistent use, I noticed the itching had vanished, and I finally felt relief! Though everyone's experience will differ, I believe this product helped significantly based on my continuous use. If you're experiencing similar symptoms, I suggest giving it a try, as it may take time, but relief is possible.

Updated: Apr 2025

Celiac details

Probiotics may aid gluten digestion

Based on 13 Researches

Nikoloudaki O, Celano G, Polo A, Cappello C, Granehäll L, et al. Novel probiotic preparation with gluten-degrading activity and potential modulatory effects on the gut microbiota. Microbiol Spectr. 2024;12:e0352423. doi:10.1128/spectrum.03524-23

We examined a promising new probiotic preparation designed to break down gluten and assist people with celiac disease. Our study included a randomized double-blind placebo-controlled trial with 70 volunteers over a 42-day period, where participants consumed increasing amounts of gluten following a gluten-free diet.

Those who took the probiotics showed significantly lower levels of residual gluten in their feces compared to the placebo group. Additionally, the probiotics appeared to enhance gut microbiota health, promoting beneficial microbial communities. However, despite these findings, we must proceed cautiously, as the overall impact on celiac disease management remains to be fully determined.

Restored gut health

Most Useful Review

3 people found this helpful

An excellent remedy for sensitive tummies, it is soy-free, gluten-free, and dairy-free—everything needed for a moody digestive system. After my child experienced digestive issues due to long courses of antibiotics, this product helped restore normal stool consistency and digestion. The results were much more effective and lasting compared to previous remedies from Russia. We will continue to purchase this for preventive care.

Updated: Apr 2025

We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.

Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.

Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.

This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.

Stopped diarrhea

Most Useful Review

4 people found this helpful

I was having severe digestion issues and daily diarrhoea. Since I began taking this product, my diarrhoea has completely stopped. I’m incredibly grateful for the relief it provides.

Updated: Mar 2026

Common Cold details

Probiotic yogurt reduces cold symptoms

Based on 8 Researches

Zhang H, Miao J, Su M, Liu BY, Liu Z. Effect of fermented milk on upper respiratory tract infection in adults who lived in the haze area of Northern China: a randomized clinical trial. Pharm Biol. 2021;59:647. doi:10.1080/13880209.2021.1929344

We investigated how consuming Qingrun yogurt, which contains the probiotic Bifidobacterium lactis, affects common colds among adults living in hazy areas. In a clinical trial with 136 participants, those who enjoyed the probiotic yogurt daily experienced fewer colds and reported milder symptoms compared to those who consumed regular yogurt.

Remarkably, it even shortened the duration and intensity of respiratory infections. The findings suggest that incorporating probiotic yogurt into our diets could be a beneficial strategy to help combat upper respiratory infections.

Stable condition

Most Useful Review

1 people found this helpful

I have been taking this every day for five years due to my weak stomach and irritable bowel. Since starting it, my condition has stabilised, and I rarely catch a common cold, feeling much healthier overall.

Updated: Apr 2025

Irritable Bowel Syndrome details

CECT 7347 reduces IBS-D symptoms

Based on 41 Researches

Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, et al. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 2024;16:2338322. doi:10.1080/19490976.2024.2338322

A randomized, double-blind, placebo-controlled trial exploring CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) revealed promising results for diarrhea-predominant irritable bowel syndrome (IBS-D).

We found that after 12 weeks, both ES1 and HT-ES1 significantly reduced symptom severity compared to a placebo, as shown by lower IBS-Symptom Severity Scale scores.

Other improvements included better stool consistency and quality of life. This study marks a breakthrough with the first positive findings for a probiotic or postbiotic from this strain specifically for IBS-D patients.

Bowel issues resolved

Most Useful Review

1 people found this helpful

This is a great product; many of my bowel issues disappeared immediately upon using it.

Updated: Mar 2026

Acne details

Probiotics improve acne severity after twelve weeks

Based on 18 Researches

Lin HW, Tam KW, Huang YC. Efficacy of oral probiotics in patients with acne: a systematic review and meta-analysis of randomized trials. Clin Exp Dermatol. 2025;51:68. doi:10.1093/ced/llaf388

We analyzed nine randomized trials involving 623 acne patients to see whether probiotics could help reduce breakouts. Early results at four weeks were modest, but after twelve weeks, probiotics showed real promise. They significantly reduced disease severity, lowered the total number of lesions, and even improved skin hydration and oil content compared to placebo.

The good news? Probiotics were well-tolerated with no major side effects reported. While more research is needed, these findings suggest probiotics may offer a genuine therapeutic benefit for people struggling with acne.

Reduces acne

Most Useful Review

1 people found this helpful

Excellent for improving digestion and gut health; I've also noticed a reduction in my acne since I began using it.

Updated: Apr 2026

Bloating details

Bifidobacterium lactis alleviates bloating

Based on 34 Researches

Agrawal A, Houghton LA, Morris J, Reilly B, Guyonnet D, et al. Clinical trial: the effects of a fermented milk product containing Bifidobacterium lactis DN-173 010 on abdominal distension and gastrointestinal transit in irritable bowel syndrome with constipation. Aliment Pharmacol Ther. 2009;29:104. doi:10.1111/j.1365-2036.2008.03853.x

We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.

Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.

7.5

Less bloating

Most Useful Review

4 people found this helpful

After two months, my bloating and gas have significantly decreased. Thank you for this product!

Updated: Mar 2026

Cold details

2 people found this helpful

I've been taking this daily for about five years. Despite having a weak stomach and irritable bowel syndrome, my condition has become much more stable since I started. I take it in the morning, and I have a good bowel movement after breakfast. I feel like I've stayed healthy and have not caught a cold these past few years.

Updated: Mar 2026

Constipation details