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NOW Supplements CoQ10 100 mg
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Coenzyme Q10 (CoQ10)
100 mg
*
Hawthorn Berry (Crataegus laevigata and/or monogyna) (Fruit)
400 mg
*

The product is found useful for the following medical conditions

High Cholesterol details

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.2
USERS' SCORE
Good
Based on 15 Reviews
8.9
9
CoQ10 lowers cholesterol levels
Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
Most Relevant Research
We delved into the effects of coenzyme Q10 (CoQ10) supplementation on cholesterol levels in adults to determine how it can influence lipid profiles. Through a thorough meta-analysis of fifty randomized controlled trials involving nearly 2800 participants, we explored its potential benefits for reducing cholesterol levels effectively.

Our findings indicated that CoQ10 supplementation significantly lowered levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG), while simultaneously increasing high-density lipoprotein cholesterol (HDL-C). This effect was particularly pronounced at a dosage of 400 to 500 mg per day, which was shown to produce the best results in terms of reducing TC.

Overall, the study provided strong evidence that CoQ10 could be a valuable ally in managing high cholesterol, helping to achieve a healthier lipid profile in adults. This research sheds light on a promising dietary supplement that might assist individuals seeking to improve their cholesterol levels effectively.
9.5
Improved blood flow
Most Useful Review
Coenzyme Q10 has been excellent for my cardiovascular system. It enhances blood flow, strengthens blood vessel walls, and protects against cholesterol plaques. It’s essential for the elderly and beneficial for younger individuals recovering from Covid.

Cardiovascular Disease details

SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
USERS' SCORE
Good
Based on 43 Reviews
8.7
9
CoQ-10 reduces mortality, improves capacity
Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysis.
Most Relevant Research
We explored the effects of coenzyme Q10 (CoQ-10) on heart failure (HF) patients by analyzing past literature. Our systematic review examined studies from MEDLINE and the Cochrane Library, focusing on how CoQ-10 influences outcomes like HF-related mortality, exercise capacity, and left ventricular ejection fraction (LVEF).

The results from 16 studies showed some promising findings. CoQ-10 was found to significantly lower HF-related mortality by 40%, which is a notable benefit for patients. Additionally, we observed improvements in exercise capacity for those taking CoQ-10. However, when it came to the impact on LVEF, the results were not statistically significant. While there wasn’t a clear-cut improvement in LVEF, we acknowledge that this aspect needs further exploration to fully understand CoQ-10's potential.

In summary, CoQ-10 appears to be effective in reducing mortality rates and enhancing exercise capacity among heart failure patients. Nonetheless, the effect on LVEF is still uncertain and merits additional investigation.
9.5
Elderly essential
Most Useful Review
Coenzyme Q10 positively affects the heart and helps reduce the risk of cardiovascular disease. As we age, our body’s natural production decreases, leading to serious health issues. It's a crucial supplement for the elderly.

Angina details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.7
8
Coenzyme Q10 improves angina symptoms
[Coenzyme q10 in complex therapy of patients with ischemic heart disease].
Most Relevant Research
We focused on the effectiveness and safety of coenzyme Q10 as a treatment for patients dealing with ischemic heart disease and stable angina, specifically those at class II-III levels. Over the course of eight weeks, participants took a daily dosage of 60 mg of coenzyme Q10 alongside their standard treatment regimen.

The results were promising; we observed that patients reported significant improvements in their clinical status related to angina symptoms. Importantly, this improvement occurred without any major side effects, indicating that coenzyme Q10 could be a beneficial addition to the treatment plan for those living with this condition.

However, it is essential to note that since coenzyme Q10 was used in conjunction with standard treatments, it is challenging to pinpoint its isolated effects conclusively. Future studies could help clarify how well coenzyme Q10 works on its own, but for now, the findings suggest it may be a valuable component of therapy for angina.
10
Zero attacks now
Most Useful Review
At 51, I have experienced angina symptoms since I was 20. I have been evaluating the quality of CoQ-10 products. A high-quality product puts my symptoms into remission, while lower quality results in flare-ups. This product deserves a 10-star rating; I’ve had no attacks since starting it. Now, I take 100mg every other day and continue to be symptom-free. I also take flax oil with it, by the way.

Autoimmune Disorder details

SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Idebenone improves lupus symptoms
Improved Mitochondrial Metabolism and Reduced Inflammation Following Attenuation of Murine Lupus With Coenzyme Q10 Analog Idebenone.
Most Relevant Research
We explored the potential benefits of idebenone, a synthetic analog of coenzyme Q10, in treating autoimmune disorders, specifically lupus, in mouse models. By administering idebenone to mice with lupus for eight weeks, we aimed to investigate its impact on disease activity and organ damage.

Our findings showed that idebenone led to a significant reduction in disease severity. Mice that received idebenone exhibited lower mortality rates and improvements in kidney function, indicated by reduced glomerular inflammation and lower levels of certain inflammatory markers. The treatment also minimized the production of proinflammatory cytokines and enhanced mitochondrial metabolism.

Besides benefiting the kidneys, idebenone diminished markers of inflammation throughout the body, which is crucial since lupus often results in systemic damage. Importantly, we noticed that idebenone improved overall metabolism in these mice without causing obvious side effects.

This research supports the idea that modulating mitochondrial function can be a promising therapeutic strategy for managing lupus, opening the door for future studies on its effectiveness in humans.
9.5
Significant improvement
Most Useful Review
Excellent. I ordered it for my mother, who suffers from an autoimmune disorder and high blood pressure. It has greatly improved her condition. The quality and ingredients are remarkable. Praise be to God.

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.7
USERS' SCORE
Good
Based on 15 Reviews
8.6
8
Ubiquinol-10 benefits chronic fatigue syndrome
Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome.
Most Relevant Research
We embarked on a study to investigate the impact of ubiquinol-10—an active form of coenzyme Q10—on patients suffering from chronic fatigue syndrome (CFS). Our research comprised two parts: an open-label study involving 20 patients and a randomized, double-blind, placebo-controlled trial with 43 participants.

In the open-label segment, patients took 150 mg of ubiquinol-10 daily for eight weeks, and both the participants and physicians knew who was receiving the supplement. The results were promising, suggesting improvements in various symptoms of CFS.

Following this, in the randomized trial, participants were assigned to either ubiquinol-10 or a placebo for 12 weeks, with neither the patients nor the doctors aware of who received which treatment. Outcomes showed that those taking ubiquinol-10 experienced significant benefits, reinforcing the notion that this supplement can positively influence CFS symptoms.

Overall, this study suggests that adding ubiquinol-10 to a treatment plan could be a helpful strategy for improving the lives of those dealing with chronic fatigue syndrome.
9.5
ATP production
Most Useful Review
Coenzyme Q10 is essential for ATP production in the mitochondria, crucial for exercise and tackling chronic fatigue syndrome. It diminishes oxidative stress, enhancing muscle function and reducing fatigue.

Aortic Stenosis details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
10
Relief from symptoms
Most Useful Review
I've experienced severe aortic stenosis, and this has completely alleviated my angina and arrhythmia. I highly recommend the quality of Now Foods supplements, as I've used them consistently for years. Their prices and quality are unbeatable!

Headache details

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
Coenzyme Q10 shows effectiveness against migraines
A Comparative Study on the Efficacy of Coenzyme Q10 and Amitriptyline in the Prophylactic Treatment of Migraine Headaches in Children: A Randomized Controlled Trial.
Most Relevant Research
We investigated the effectiveness of coenzyme Q10 in treating migraines in children, comparing it with the commonly prescribed medication, amitriptyline. Our study involved 72 children, aged 5 to 15, who met the criteria for migraine diagnosis set by the International Headache Society.

Over a three-month period, we observed that coenzyme Q10 had positive therapeutic effects, particularly for those requiring long-term treatment. While amitriptyline provided quicker results, the differences between the two treatments in effectiveness were not significantly noticeable after three months. Both treatments led to improvements in the quality of life for the children involved.

Importantly, we noted that children taking amitriptyline experienced more side effects compared to those receiving coenzyme Q10. This finding positions coenzyme Q10 as a promising option due to its comparable effectiveness and better tolerated adverse effect profile.
9.5
Headache solution
Most Useful Review
If you are struggling with headaches, this is the solution you need!

Migraine details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 4 Reviews
8.6
8
Co-Q10 potentially benefits migraine patients
The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial.
Most Relevant Research
We investigated how Coenzyme Q10 (Co-Q10) affects migraine symptoms in a well-structured clinical trial. Over the course of 12 weeks, 84 women aged 18 to 50 diagnosed with episodic migraines participated in a randomized, double-blind study, where they received either Co-Q10 (400 mg/day) or a placebo.

Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.

However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
8.8
Significant reduction
Most Useful Review
CoQ10 has helped me significantly with my chronic migraines. I used to experience about five migraine days per week, but now it’s down to two. While it's still challenging, compared to my previous daily occurrences, this improvement feels miraculous. I take 200 mg in the morning and evening. I’ve also tried ubiquinol, which was more expensive, but this CoQ10 works better for me.

Blood Clot details

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
CoQ10 reduces harmful blood clots
Coenzyme Q10 Upregulates Platelet cAMP/PKA Pathway and Attenuates Integrin αIIbβ3 Signaling and Thrombus Growth.
Most Relevant Research
We explored how coenzyme Q10 (CoQ10), a natural compound found in various foods, impacts blood clotting functions. Through a well-structured study, we utilized a randomized, double-blind, placebo-controlled trial with dyslipidemic patients, alongside in vitro tests on human platelets.

Our findings demonstrated that CoQ10 effectively reduces platelet aggregation, granule secretion, platelet spreading, and clot retraction. This means that CoQ10 can help prevent excessive blood clot formation, which is crucial for cardiovascular health.

We observed that CoQ10 works mainly by enhancing a signaling pathway involving cyclic AMP (cAMP) which ultimately diminishes the signaling of integrin αIIbβ3, a key player in platelet function. In addition, the treatment showed promising results in reducing thrombus growth in an animal model, suggesting significant in vivo benefits as well.

This study highlights the potential of CoQ10 supplementation as a protective measure for individuals at risk of cardiovascular diseases by regulating platelet-related processes involved in clotting.
8.8
Blood pressure reduction
Most Useful Review
When I measured my blood pressure, I discovered I had high blood pressure. After trying this supplement, my blood pressure decreased significantly.

Back Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
8.8
Dog's pain relief
Most Useful Review
Five stars! This product works excellently to relieve my dog's back pain when given twice daily!

Liver Disease details

SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.6
USERS' SCORE
Good
Based on 2 Reviews
8.3
9
Coenzyme Q10 improves liver health
Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
Most Relevant Research
We conducted a study to explore the effects of high-dose coenzyme Q10 supplementation on patients suffering from liver disease related to metabolic dysfunction, known as Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD). In a well-structured double-blind, placebo-controlled trial with sixty participants, half received 240 mg of coenzyme Q10 daily, while the other half received a placebo for six months.

Our findings were promising. Patients taking coenzyme Q10 showed significant improvements in various aspects of their health related to liver functions and cardiovascular health. Specifically, we observed a reduction in liver fat content, as assessed by the controlled attenuation parameter, along with better blood vessel function and heart performance. For instance, the flow-mediated dilation of the brachial artery and the coronary flow reserve significantly improved in those receiving the supplement.

Interestingly, while the placebo group did not show any improvements during the six-month period, the coenzyme Q10 group demonstrated a clear correlation between the reduction in liver fat and enhancements in micro- and macrovascular functions. These results suggest that coenzyme Q10 could potentially be a beneficial treatment option for those battling MASLD.
8.8
Improved condition
Most Useful Review
Excellent! After taking this medicine, my hypothyroid condition has improved significantly.

Heart Disease details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Good
Based on 80 Reviews
8.1
9
CoQ-10 improves heart failure outcomes
Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysis.
Most Relevant Research
We explored the effectiveness of coenzyme Q10, commonly known as CoQ-10, in treating heart failure (HF) by reviewing multiple studies. Our systematic analysis included research from respected databases like MEDLINE and the Cochrane Library, where we focused on three main outcomes: heart failure-related mortality, exercise capacity, and left ventricular ejection fraction (LVEF).

From the 16 studies we examined, we observed that CoQ-10 treatment significantly decreased HF-related mortality by an impressive 40%. Additionally, we noted improvements in exercise capacity among patients, indicating that CoQ-10 could help individuals with heart failure engage in more physical activity and improve their quality of life.

However, when it came to LVEF—the measurement of how well the heart pumps blood—CoQ-10 did not show significant changes. Despite this, we believe that its potential impact on LVEF should be investigated further, as the data does suggest there may be benefits that warrant additional research.

In summary, while CoQ-10 proved to be beneficial in enhancing exercise capacity and reducing mortality associated with heart failure, the exact effects on LVEF remain unclear and would benefit from more focused studies in the future.
9.5
Rejuvenates heart
Most Useful Review
After a month of using Now Foods' Q10, I’m pleased with the results. This coenzyme energises cells, which is vital for combating heart disease. It's also a potent antioxidant, promoting overall health.

Bone Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8
9.5
Heart improvement
Most Useful Review
Excellent quality and good composition. I took it to support my liver while on statins and it has positively affected my heart. Previously, I experienced bone pain in my chest area, but now everything is fine. I highly recommend it.

Food Poisoning details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 1 Review
7.7
0
Severe allergic reaction
Most Useful Review
I do not recommend this! I believed it would help, as I read about the benefits of Q10 for older people. I neglected to notice the hawthorn added; it was poison for me! Initially, I felt calmer, but then chaos ensued—my head throbbed, my heart raced, and I could not sleep. After 6 days, I stopped. Three weeks later, I tried again and ended up in hospital with a heart attack! I learned I have an allergy to hawthorn. This remedy isn't worth the risk!

Heart Attack details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Medium or Average
Based on 23 Reviews
6.8
9
Coenzyme Q10 aids heart recovery
Coenzyme Q10 Modulates Remodeling Possibly by Decreasing Angiotensin-Converting Enzyme in Patients with Acute Coronary Syndrome.
Most Relevant Research
We investigated how coenzyme Q10 might help with heart function after a heart attack, particularly focusing on its role in heart remodeling. In a well-structured study involving 55 patients with left ventricular dysfunction following an acute myocardial infarction, we compared the effects of coenzyme Q10 to a placebo over a 24-week period.

Through careful measurements using echocardiography, we observed notable improvements in the walls of the heart and overall heart mass for those taking coenzyme Q10. Specifically, the thickness of the heart walls decreased, and the left ventricular mass was reduced more significantly than in those receiving the placebo.

Additionally, coenzyme Q10 appeared to maintain heart shape and prevent worsening of heart function compared to the placebo group. Our results also highlighted a significant drop in angiotensin-converting enzyme (ACE) levels in the coenzyme Q10 group, suggesting beneficial effects on heart remodeling and function during recovery from a heart attack.
9.5
Post-heart attack recovery
Most Useful Review
I gave this to my father after his heart attack, and he’s doing wonderfully now. While it’s not solely responsible, combined with other treatments, it has had an amazing effect. You won't regret trying it.
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