Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Iron (elemental) (from 180 mg Ferrous Bisglycinate)(Ferrochel™)
36 mg
200%
The product is found useful for the following medical conditions
Food Poisoning details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.8
8
We explored how iron influences food poisoning, particularly in the context of campylobacteriosis, a common foodborne illness. Our focus was on the effects of deferoxamine (DESF), an iron-chelating compound, when administered orally to mice before they were infected.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
In our study, we included microbiota-depleted IL-10 mice that received DESF through their drinking water starting a week ahead of being exposed to the Campylobacter strain known as 81-176. While we did not observe any significant reduction in the levels of the bacteria in the gastrointestinal tract, we did identify some noteworthy improvements in the overall health status of the infected mice by the sixth day post-infection.
These findings suggested that DESF treatment seemed to alleviate the disease's impact, manifesting as reduced cell death in the colon, lower numbers of immune cells like neutrophils accumulating in the large intestines, and decreased levels of inflammatory markers, including IFN-γ and MCP-1, in both the intestines and systemically.
Overall, our research illustrates the potential for iron-targeting strategies to positively affect the progression and severity of campylobacteriosis, offering a new outlook for treatment approaches when conventional antibiotic methods are not recommended.
10
Improved condition
Most Useful Review
163 people found this helpful
This is a very cool find! After starting on supplemental iron, my ferritin levels rose from 40 to 70, significantly alleviating my lethargy and constant fatigue. My hair loss has also reduced. I took one capsule daily with food for two months, and I definitely recommend it! Let me know if you find my review helpful.
Knee Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 8 Reviews
8.8
8
We focused on the effects of iron treatment as part of a broader strategy for managing blood loss and pain in patients undergoing staged bilateral total knee arthroplasty (TKA) within a single hospital stay. In our study, we compared two groups of patients: one receiving a newly introduced multimodal blood management (MBM) approach that included preoperative oral iron treatment, and a control group that only received standard care.
Our findings were promising. The group treated with the MBM protocol experienced significantly lower rates of blood transfusion—only 9% of patients required one—compared to 32.4% in the control group. This approach not only reduced the need for additional blood transfusions but also led to improvements in postoperative hemoglobin levels and reduced pain and swelling in the knees after surgery.
The results suggest that incorporating iron treatment in a comprehensive management program can effectively help alleviate knee pain and enhance recovery from surgery. Best of all, this was achieved without leading to any significant complications, indicating a safe and economical option for improving outcomes in TKA patients.
Our findings were promising. The group treated with the MBM protocol experienced significantly lower rates of blood transfusion—only 9% of patients required one—compared to 32.4% in the control group. This approach not only reduced the need for additional blood transfusions but also led to improvements in postoperative hemoglobin levels and reduced pain and swelling in the knees after surgery.
The results suggest that incorporating iron treatment in a comprehensive management program can effectively help alleviate knee pain and enhance recovery from surgery. Best of all, this was achieved without leading to any significant complications, indicating a safe and economical option for improving outcomes in TKA patients.
9
Improved mobility
Most Useful Review
49 people found this helpful
Excellent. I have suffered from terrible knee pain due to iron deficiency. Thankfully, I no longer feel light-headed or weak in my knees, and I can now walk and take the stairs without fatigue. I strongly recommend this treatment for anyone facing iron deficiency.
Cardiovascular Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 2 Reviews
8.7
7
Iron deficiency impacts heart failure
Our investigation focused on the impact of iron deficiency in patients with worsening chronic heart failure, seeking clarity on how it affects their condition and recovery. We enrolled 163 patients from multiple centers who were hospitalized for this serious health issue. By evaluating iron deficiency at discharge, we distinguished those affected by low iron levels and compared various health indicators between groups.
We discovered that over half of the patients, 54.6%, had iron deficiency. Those with lower iron were more likely to exhibit signs of congestion and were categorized into more advanced heart failure classes. Interestingly, their levels of NT-proBNP, a crucial marker associated with heart failure, were significantly higher upon admission and didn’t improve much during their hospital stay.
While we found that mortality rates within 30 days had no significant difference between patients with and without iron deficiency, a notable increase in deaths was observed at 90 days post-discharge for those with iron deficiency. This suggests that iron levels could potentially influence recovery, especially in the longer term.
In conclusion, patients dealing with both chronic heart failure and iron deficiency showed more unresolved symptoms and poorer outcomes post-discharge. These findings highlight the importance of monitoring iron levels in patients facing heart issues, paving the way for future studies into treatment effectiveness and potential benefits of iron therapies.
We discovered that over half of the patients, 54.6%, had iron deficiency. Those with lower iron were more likely to exhibit signs of congestion and were categorized into more advanced heart failure classes. Interestingly, their levels of NT-proBNP, a crucial marker associated with heart failure, were significantly higher upon admission and didn’t improve much during their hospital stay.
While we found that mortality rates within 30 days had no significant difference between patients with and without iron deficiency, a notable increase in deaths was observed at 90 days post-discharge for those with iron deficiency. This suggests that iron levels could potentially influence recovery, especially in the longer term.
In conclusion, patients dealing with both chronic heart failure and iron deficiency showed more unresolved symptoms and poorer outcomes post-discharge. These findings highlight the importance of monitoring iron levels in patients facing heart issues, paving the way for future studies into treatment effectiveness and potential benefits of iron therapies.
10
Improved hemoglobin levels
Most Useful Review
391 people found this helpful
Awesome additive! I ordered this iron supplement for my friend who suffers from muscle myositis and has low hemoglobin due to hormone treatment. She struggled with fatigue and muscle pain, despite trying various pharmacy drugs. After 3 months on this iron, her hemoglobin rose from 117 to 143, and she felt much better without any side effects. She even returned to work! Now, I’m taking it myself for prevention. Many thanks to the manufacturers!
Allergies details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.8
USERS' SCORE
Good
Based on 13 Reviews
8.6
8
We examined the rise of hypersensitivity reactions (HRs) linked to iron agents, especially as their usage in treating iron deficiency has increased. In this study, we evaluated the clinical features of patients who experienced immediate hypersensitivity reactions (IHRs) to both oral and intravenous (IV) iron preparations.
Our analysis included the medical records of 96 patients with a history of these reactions. Among them, 47 had reactions to oral iron, while 49 reacted to IV iron. We conducted skin-prick tests with various iron salts, but found that these tests weren't very helpful for diagnosing IHRs. In fact, only a small percentage showed a positive reaction.
Interestingly, we noted that patients who were sensitive to IV iron experienced more severe reactions, including cases of anaphylaxis. Despite the challenges in diagnosing these allergies, we successfully conducted desensitization treatments for 15 patients needing iron, specifically using ferric carboxymaltose. This approach proved to be safe and effective, marking an important option for patients requiring iron therapy despite their hypersensitivity.
Our analysis included the medical records of 96 patients with a history of these reactions. Among them, 47 had reactions to oral iron, while 49 reacted to IV iron. We conducted skin-prick tests with various iron salts, but found that these tests weren't very helpful for diagnosing IHRs. In fact, only a small percentage showed a positive reaction.
Interestingly, we noted that patients who were sensitive to IV iron experienced more severe reactions, including cases of anaphylaxis. Despite the challenges in diagnosing these allergies, we successfully conducted desensitization treatments for 15 patients needing iron, specifically using ferric carboxymaltose. This approach proved to be safe and effective, marking an important option for patients requiring iron therapy despite their hypersensitivity.
9
No allergies noted
Most Useful Review
306 people found this helpful
Excellent hardware. It raised my sister's hemoglobin; it didn't work the first time. No allergies were identified.
Blurred Vision details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.6
9
Vision enhancements
Most Useful Review
84 people found this helpful
I have been taking this vitamin for over a month now, and I cannot believe how effective it is! Initially, I was sceptical, assuming it wouldn't work as it's a natural product. However, I started noticing improvements in my vision and an increase in focus. Then, one day, my vision dramatically improved, as if something in my brain had just reactivated!
Chest Pain details
SCIENTIFIC SCORE
Likely Very Effective
Based on 4 Researches
9.1
USERS' SCORE
Good
Based on 4 Reviews
8.6
9
We explored the intriguing link between iron treatment and angina symptoms in a unique case involving a 46-year-old woman with endometrial cancer. This patient arrived in the emergency department with acute chest pain, yet her heart was healthy based on ECG results. Instead, we found that her chest pain was a result of critically low hemoglobin levels caused by severe iron deficiency anemia.
Over the past six months, the patient experienced prolonged and heavy menstruation, which contributed to her anemia. After administering six units of packed red blood cells and an iron infusion, we witnessed a remarkable turnaround. The chest pain resolved, and her blood counts improved significantly.
This case is particularly noteworthy for highlighting how essential it is for women experiencing chest pain to be evaluated for anemia. It serves as a crucial reminder that understanding a patient's gynecological history can shed light on their overall health and symptoms. The link between iron treatment and relief from chest pain underscores the importance of recognizing the systemic effects of anemia.
Over the past six months, the patient experienced prolonged and heavy menstruation, which contributed to her anemia. After administering six units of packed red blood cells and an iron infusion, we witnessed a remarkable turnaround. The chest pain resolved, and her blood counts improved significantly.
This case is particularly noteworthy for highlighting how essential it is for women experiencing chest pain to be evaluated for anemia. It serves as a crucial reminder that understanding a patient's gynecological history can shed light on their overall health and symptoms. The link between iron treatment and relief from chest pain underscores the importance of recognizing the systemic effects of anemia.
9
Improved well-being
Most Useful Review
46 people found this helpful
I was shocked by the results of taking this iron! My hemoglobin was consistently low due to inadequate iron in my diet. After starting this chelative iron, I noticed improved health and a significant rise in my hemoglobin from 113 to 144. I experienced no side effects, such as chest pain, constipation, or nausea. I highly recommend this iron supplement for anyone in a similar situation.
Celiac details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.1
USERS' SCORE
Good
Based on 7 Reviews
8.5
8
We conducted a study exploring whether iron deficiency might influence the development of coeliac disease through a method called Mendelian randomization. By analyzing genetic data from nearly 337,000 individuals, we discovered a link between lower iron levels and a higher risk of coeliac disease.
The findings suggest that maintaining good iron status could be vital in preventing this condition. However, while our results are promising, they do not establish a definitive cause-and-effect relationship.
The findings suggest that maintaining good iron status could be vital in preventing this condition. However, while our results are promising, they do not establish a definitive cause-and-effect relationship.
9
Effective iron supplement
Most Useful Review
1 people found this helpful
Ferrochel iron bisglycinate has effectively corrected my iron deficiency related to celiac disease, utilising a dual absorption mechanism. Its bioavailability approaches 90-100%, being 2.6 times safer than ferrous sulfate. I found that two doses in one capsule quickly raised my iron levels. Monitoring ferritin, instead of serum iron, is crucial in detecting anaemia. If you struggle with morning fatigue despite normal haemoglobin levels, checking ferritin will reveal much about your health. An equivalent from Russian pharmacies is Sideral forte, but it's considerably pricier.
Chemotherapy details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 6 Reviews
8.5
9
We explored the impact of iron on chemotherapy effectiveness, particularly in the treatment of osteosarcoma (OS). The study revealed promising insights into how combining iron with eriodictyol and cisplatin could promote ferroptosis—a form of regulated cell death that can improve the overall effectiveness of cancer therapies.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
The researchers discovered that eriodictyol can curb a protein known as BACH1, which leads to reduced production of GPX4, a key player in protecting cells from ferroptosis. By diminishing GPX4 levels, this combination appears to push cancer cells towards ferroptosis more effectively.
Moreover, employing hollow mesoporous nanocubes to deliver eriodictyol and cisplatin seamlessly combines these agents to enhance cell death in OS. Through multiple mechanisms, including the depletion of protective molecules and the direct initiation of fatal processes in cancer cells, the nanocomplex showed impressive results in both lab tests and animal studies.
Importantly, the treatment demonstrated effectiveness without causing significant harm to other organs, hinting at its potential as a therapeutic strategy for OS patients in need of better treatment options.
9
Severe anaemia recovery
Most Useful Review
1 people found this helpful
After chemotherapy, I became severely anemic. Following a month and a half in hospital, my condition improved, much to the doctors' surprise. I continue taking the medication until the end of my course, which notably does not cause constipation.
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 118 Reviews
8.5
We explored the effects of iron supplementation on individuals suffering from iron deficiency, specifically looking at its impact on symptoms like chronic fatigue syndrome (CFS). This was done through a well-structured study involving 176 blood donors who were iron deficient, with a randomized controlled trial design.
Participants were assigned to receive either intravenous iron or oral iron supplements. Over an 8-12 week period, we assessed changes in symptoms related to iron deficiency, including CFS, restless legs syndrome (RLS), sleeping disorders, and overall quality of life.
The results indicated that iron supplementation may significantly improve the symptoms associated with iron deficiency among blood donors. By addressing the iron deficiency, we noted improvements not only in fatigue but also in wellbeing, confirming that targeted iron treatment can be beneficial for those struggling with chronic fatigue linked to low iron levels. This is an exciting finding for both clinicians and patients, shedding light on a relatively simple intervention that can enhance quality of life.
Participants were assigned to receive either intravenous iron or oral iron supplements. Over an 8-12 week period, we assessed changes in symptoms related to iron deficiency, including CFS, restless legs syndrome (RLS), sleeping disorders, and overall quality of life.
The results indicated that iron supplementation may significantly improve the symptoms associated with iron deficiency among blood donors. By addressing the iron deficiency, we noted improvements not only in fatigue but also in wellbeing, confirming that targeted iron treatment can be beneficial for those struggling with chronic fatigue linked to low iron levels. This is an exciting finding for both clinicians and patients, shedding light on a relatively simple intervention that can enhance quality of life.
9
Increased iron levels
Most Useful Review
1272 people found this helpful
Effective iron! It raised my ferritin levels. I felt overwhelmed and fatigued, with my ferritin at 18.3 in January. After much research, I opted for this iron bisglycinate, which has a good dosage and quality. I took it twice daily with vitamin C, and my energy improved significantly.
Heart Attack details
SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Good
Based on 8 Reviews
8.5
9
Macrophage EVs combat iron overload
We delved into the connection between iron overload and its effects on heart function after a heart attack, also known as myocardial infarction (MI). Our research focused on utilizing macrophage-derived extracellular vesicles (EVs) as a natural therapy to help with excessive iron levels in the heart.
The downside of existing chemical iron chelators is that they often come with side effects, so we sought a safer and more effective solution. By isolating EVs from macrophages, we found that they serve as a biological chelator for iron. When we introduced these EVs to heart cells affected by low oxygen levels, they significantly reduced iron overload and minimized the oxidative stress linked to this excess iron.
Notably, these EVs work by harnessing a receptor called transferrin receptor (TfR), which helps them grab onto and remove the surplus protein-bound iron. In our observations, when the EVs lacked TfR, they were ineffective in protecting heart tissue. This shows that leveraging macrophage-derived EVs could offer a new approach in treating heart damage due to iron overload, especially after myocardial infarction.
The downside of existing chemical iron chelators is that they often come with side effects, so we sought a safer and more effective solution. By isolating EVs from macrophages, we found that they serve as a biological chelator for iron. When we introduced these EVs to heart cells affected by low oxygen levels, they significantly reduced iron overload and minimized the oxidative stress linked to this excess iron.
Notably, these EVs work by harnessing a receptor called transferrin receptor (TfR), which helps them grab onto and remove the surplus protein-bound iron. In our observations, when the EVs lacked TfR, they were ineffective in protecting heart tissue. This shows that leveraging macrophage-derived EVs could offer a new approach in treating heart damage due to iron overload, especially after myocardial infarction.
9
Improved hemoglobin levels
Most Useful Review
7 people found this helpful
The rescue! Three years ago, I struggled with treating my anaemia; my haemoglobin was stuck at 80. After taking this specific iron supplement for two years, my haemoglobin is now consistently 140. I no longer experience the headaches I used to, nor am I freezing like before. This product is irreplaceable for me.
Hypothyroidism details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 10 Reviews
8.5
9
Improved energy
Most Useful Review
7 people found this helpful
Super supplement! I've suffered from iron deficiency and hypothyroidism for years. Nothing helped until I tried this chelated iron. It greatly improved my condition, eliminating dizziness and fatigue. I take it regularly and will continue to monitor my ferritin levels. Overall, it’s a fantastic product for managing my iron levels.
Tinnitus details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.5
9
Significant improvement
Most Useful Review
1 people found this helpful
The anaemia issue has improved, and I no longer experience constipation. The price is reasonable. When taken with vitamin C, there's no discomfort while eating. Symptoms of dizziness and tinnitus caused by anaemia have significantly improved. Even postural hypotension has reduced. This iron supplement is much more affordable than the new ones recommended by the hospital that also avoid constipation. I will definitely repurchase.
Athlete’s Foot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
Resolved itching
Most Useful Review
My mother complained of itchy legs at night, which I discovered was due to an iron deficiency. I bought these supplements for her, and after just a few days, she stopped complaining about the itching associated with athlete’s foot.
Back Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.8
USERS' SCORE
Good
Based on 18 Reviews
8.4
9
We investigated how a substance called HP influences iron-related oxidative stress and its connection to back pain in a common condition known as lumbar spinal stenosis (LSS). LSS causes significant discomfort and disability, particularly for older adults, primarily due to hypertrophy of the ligamentum flavum, which can be exacerbated by oxidative stress stemming from imbalanced iron levels.
Our study involved exposing spinal cord neuron cultures to iron before treatment with HP at varying concentrations. We assessed the cells' health using tests to measure viability and cell damage. Additionally, in a rat model of LSS, we provided different doses of HP and monitored the effects over several weeks. The results were compelling: HP not only protected neurons from iron-induced damage but also promoted cellular health by boosting antioxidant defenses through a pathway known as NRF2.
Over the course of our observations, we noted significant reductions in both inflammation and oxidative stress markers in the rats treated with HP. This regulation of excess iron appeared to alleviate mechanical allodynia—a condition causing painful responses to light touch—and improved the overall functionality of the affected rats.
Our findings suggest that HP therapy may offer a promising approach to manage iron-related oxidative stress in LSS and the associated back pain, indicating a new avenue for treatment that could enhance quality of life.
Our study involved exposing spinal cord neuron cultures to iron before treatment with HP at varying concentrations. We assessed the cells' health using tests to measure viability and cell damage. Additionally, in a rat model of LSS, we provided different doses of HP and monitored the effects over several weeks. The results were compelling: HP not only protected neurons from iron-induced damage but also promoted cellular health by boosting antioxidant defenses through a pathway known as NRF2.
Over the course of our observations, we noted significant reductions in both inflammation and oxidative stress markers in the rats treated with HP. This regulation of excess iron appeared to alleviate mechanical allodynia—a condition causing painful responses to light touch—and improved the overall functionality of the affected rats.
Our findings suggest that HP therapy may offer a promising approach to manage iron-related oxidative stress in LSS and the associated back pain, indicating a new avenue for treatment that could enhance quality of life.
9
Dizziness reduction
Most Useful Review
11 people found this helpful
I previously took a Japanese heme iron supplement but experienced dizziness, nausea, and migraines. After switching to a high-quality iron supplement, I noticed an improvement in my dizziness by the second day and my migraines vanished within a week. Though the capsules have an iron smell, I highly recommend this for anyone who has not found relief with Japanese heme iron.
Bacterial Infection details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.4
7.5
Improved mood
Most Useful Review
2 people found this helpful
Slowly, but it’s effective. As a breastfeeding vegan mother, I experienced iron deficiency due to a bacterial infection. I chose this product for its good dosage. Fortunately, it hasn’t caused any constipation. I also maintain a fibre-rich diet, take B12, iodine, and stay hydrated. I use this iron supplement every other day to avoid overdose, as my prenatal vitamins contain iron too. I take it after lunch with vitamin C. Since I started, my skin isn't as pale, my mood is improving, and I can feel it working. I recommend this product. I also drink dandelion root tea to aid iron absorption.
Pelvic Pain details
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.2
USERS' SCORE
Good
Based on 26 Reviews
8.4
7
We investigated the role of ferroptosis in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). By using an experimental model, we applied treatments with deferoxamine (DFO) and edaravone (EDA) to inhibit ferroptosis.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
Our findings revealed that targeting ferroptosis may reduce inflammation, fibrosis, and mast cell activity, potentially easing pelvic pain associated with CP/CPPS. These results highlight a new pathway for treating this challenging condition, offering hope for improved management strategies.
9
Reduced pelvic pain
Most Useful Review
2 people found this helpful
On discovering Dr. Fujikawa's book, I started taking iron for severe menstrual pain and PMS. Over three years, it has greatly eased my lower back pain and reduced dizziness when standing and morning fatigue. I worry about running out of this supplement!
Sleep Apnea details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 6 Reviews
8.4
8
We conducted a study to discover how intravenous iron therapy impacts sleep apnea in patients suffering from heart failure, anemia, and iron deficiency. Patients were randomly assigned to receive either ferric carboxymaltose or a placebo to assess changes in their sleep and respiratory function after treatment.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
Our findings revealed that the intravenous iron treatment significantly improved the hypercapnic ventilatory response, which is the way our bodies react to increased carbon dioxide levels. We observed that, in particular, patients who received iron saw a notable reduction in their apneas and hypopneas—those moments when breathing stops or becomes shallow while asleep. Specifically, the apnoea-hypopnoea index dropped to an average of 12 events per hour with treatment, compared to 19 events per hour in the placebo group.
Furthermore, those who received iron also reported better overall symptoms and had improved physical capacity during exercise tests. This suggests that iron therapy not only helps with sleep-related breathing issues but may also boost oxygen delivery during physical activities.
Overall, our study supports the notion that iron therapy could play an important role in managing sleep apnea among patients with heart failure, providing them with enhanced breathing during sleep and better quality of life.
9
Eased restless legs
Most Useful Review
My husband suffers from restless leg syndrome, so I took this since I was advised it could help with iron deficiency. After taking one before bed, he was able to sleep well.
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.4
9
Ferritin improved
Most Useful Review
1 people found this helpful
Good! I recommend it; there were no swelling or issues with my stool! My ferritin levels rose from 36 to 45 after consuming one pack in three months. I expected it to rise even more!
Vertigo details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 7 Reviews
8.4
9
Iron treatment alleviates vertigo symptoms
Our study aimed to understand how iron deficiency impacts students' experiences, particularly focusing on symptoms like vertigo and dizziness. We set out to identify undiagnosed iron deficiency among first-grade students at an upper secondary school and evaluated changes in their symptoms and lab results after three months of iron supplementation.
Through our research, we found that 12% of the students had iron deficiency, and 61% exhibited some abnormal test results related to iron levels. Notably, we observed that symptoms of vertigo and dizziness were significantly more common in those with iron deficiency. After the students received iron supplementation, we recorded notable improvements: iron levels increased, transferrin levels decreased, and importantly, there was a marked reduction in symptoms, including vertigo, irritability, and depressive feelings.
Our findings convincingly highlight that iron supplementation can be beneficial in alleviating certain symptoms, specifically vertigo and dizziness, among students struggling with iron deficiency. This connection opens doors to addressing quality of life issues tied to iron levels among young individuals.
Through our research, we found that 12% of the students had iron deficiency, and 61% exhibited some abnormal test results related to iron levels. Notably, we observed that symptoms of vertigo and dizziness were significantly more common in those with iron deficiency. After the students received iron supplementation, we recorded notable improvements: iron levels increased, transferrin levels decreased, and importantly, there was a marked reduction in symptoms, including vertigo, irritability, and depressive feelings.
Our findings convincingly highlight that iron supplementation can be beneficial in alleviating certain symptoms, specifically vertigo and dizziness, among students struggling with iron deficiency. This connection opens doors to addressing quality of life issues tied to iron levels among young individuals.
9
Helps with vertigo
Most Useful Review
I bought this for my severe menstrual anaemia, and my son, who is also anemic, takes it with me. I haven't visited the hospital, but I've noticed that my dizziness has subsided since starting this supplement.
Common Cold details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 14 Reviews
8.3
9
We explored whether home fortification of foods with multiple micronutrient powders (MNPs) impacts nutrition and health in children under two years. Analyzing 29 studies, we discovered that using MNPs significantly lowered anaemia rates by 18% and iron deficiency by 53%. Moreover, MNPs improved haemoglobin levels compared to no intervention. However, there was no notable influence on weight. While the intervention showed promise for anaemia, its direct effects on other health areas remain unclear, indicating a need for more research in this area.
9
Cold symptoms alleviated
Most Useful Review
43 people found this helpful
I cannot live without this! During childbirth, I suffered from a common cold, sore throat, and fever monthly. Despite numerous visits to the ENT department, I was desperate for relief. After learning I might be low in iron and zinc, I switched to Now Foods, which contains significantly more iron than others I'd tried. Initially, the smell made me gag, but I got used to it. I recommend purchasing from iHerb or Rakuten for better prices.
Frozen Shoulder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.3
9
Reduced stiffness
Most Useful Review
3 people found this helpful
After five months postpartum, I experienced stiffness in my hands, which I feared was rheumatism. Upon discovering my iron levels were low, I tried megavitamin therapy, including 36mg of chelated iron alongside other vitamins. Now, I’m pleased to report that the frozen shoulder and stiffness have significantly eased, and I can tie my hair again.
Adenomyosis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.2
9
Symptoms improved
Most Useful Review
Since being diagnosed with uterine adenomyosis following endometriosis and uterine fibroids, I am undergoing treatment. I've managed to stop my periods with medication, but the side effects have led to much irregular bleeding, which, coupled with anaemia, has been distressing. After I started taking one tablet at breakfast, my symptoms improved dramatically. Although I still face irregular bleeding, I believe it has been effective for my physical complaints.
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 95 Reviews
8.2
8
We examined how curcumin-mediated photodynamic therapy (CUR-PDT) induces a specific type of cell death called ferroptosis in fibroblast-like synoviocytes from rheumatoid arthritis patients.
Using a rat model, we monitored joint swelling and inflammation while analyzing key proteins involved in this process. The results indicated that CUR-PDT successfully reduces harmful cell growth and inflammation in RA cells by targeting the Nrf2-xCT-GPX4 pathway.
This finding emphasizes the potential of CUR-PDT as a treatment strategy in managing rheumatoid arthritis.
Using a rat model, we monitored joint swelling and inflammation while analyzing key proteins involved in this process. The results indicated that CUR-PDT successfully reduces harmful cell growth and inflammation in RA cells by targeting the Nrf2-xCT-GPX4 pathway.
This finding emphasizes the potential of CUR-PDT as a treatment strategy in managing rheumatoid arthritis.
9
Raised hemoglobin levels
Most Useful Review
618 people found this helpful
This is the best iron for treating my autoimmune disorder during pregnancy. Despite various prescriptions failing to help, I turned to this product. Within three weeks, my haemoglobin rose from 96 to 123, and ferritin increased from 40 to nearly 90. I also experienced no gastrointestinal issues, unlike previous products. I'm glad to share my experience; it really works!
Indigestion details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 17 Reviews
8.2
9
Well absorbed
Most Useful Review
19 people found this helpful
This iron is perfectly absorbed without inducing indigestion. After two weeks of use, my hemoglobin levels increased. I highly recommend it!
Heartburn details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 17 Reviews
8.1
10
No heartburn experienced
Most Useful Review
9 people found this helpful
I took this iron supplement during my pregnancy, alternating it with another medication. My haemoglobin levels remained normal, without the typical side effects of constipation or heartburn that I usually experience with iron supplements. The capsules were easy to swallow, and my stools did turn black, which is normal.
Leg Cramps details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 26 Reviews
8.1
7
We explored the effects of iron deficiency (ID) in patients on maintenance hemodialysis, especially regarding common symptoms like leg cramps. The study included 154 patients, all of whom had reached target hemoglobin levels, which means they were not anemic. This allowed us to focus on the impact of ID without the confounding factor of low hemoglobin.
Our findings revealed that patients with iron deficiency reported a higher severity of leg cramps compared to those without ID. Specifically, we observed that a low transferrin saturation (TSAT) level contributed significantly to the experience of pain during vascular access punctures and those annoying intradialytic leg cramps. Additionally, patients with lower ferritin levels faced more intense issues like severe fatigue and headaches during their dialysis sessions.
The results suggest that treating iron deficiency could potentially alleviate these critical symptoms, indicating that proactive iron supplementation may be beneficial for those undergoing maintenance dialysis. Addressing ID might not only improve hemoglobin levels but also enhance overall quality of life by reducing painful experiences like leg cramps.
Our findings revealed that patients with iron deficiency reported a higher severity of leg cramps compared to those without ID. Specifically, we observed that a low transferrin saturation (TSAT) level contributed significantly to the experience of pain during vascular access punctures and those annoying intradialytic leg cramps. Additionally, patients with lower ferritin levels faced more intense issues like severe fatigue and headaches during their dialysis sessions.
The results suggest that treating iron deficiency could potentially alleviate these critical symptoms, indicating that proactive iron supplementation may be beneficial for those undergoing maintenance dialysis. Addressing ID might not only improve hemoglobin levels but also enhance overall quality of life by reducing painful experiences like leg cramps.
9
Leg cramps improved
Most Useful Review
14 people found this helpful
Excellent iron! I have low haemoglobin, and conventional options didn't work for me. After switching to this iron, the results were remarkable. My leg cramps disappeared, dizziness stopped, and my overall well-being improved. I take one tablet daily with food, avoiding tea and coffee before and after to enhance absorption. Highly recommend!
Menopause details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.1
USERS' SCORE
Good
Based on 24 Reviews
8.1
9
We investigated how iron treatment affects iron levels and blood production in rats that underwent ovariectomy, a procedure mimicking menopause. By using Deferasirox, a medication often prescribed for iron overload conditions, we aimed to understand its role in managing iron levels and supporting blood health in this context.
Our study involved sixty-four female Wistar rats divided into several groups. After undergoing surgery to simulate menopause, we induced iron accumulation in them. We then treated some groups with Deferasirox at varying doses and looked into its effects on their health.
We observed that the treatment with Deferasirox led to improved conditions in several key areas. There were noticeable positive changes in the uterine tissue, an increase in white blood cells, and a decrease in harmful iron levels. Moreover, the treatment increased the body’s antioxidant capacity, helping fight oxidative stress commonly seen in menopausal conditions.
Deferasirox also had beneficial effects on bone health and the overall functioning of blood-producing cells. Additionally, it influenced gene expressions related to iron metabolism and blood production. Overall, we found that Deferasirox plays an important role in managing iron and enhancing blood health in rats experiencing conditions similar to menopause.
Our study involved sixty-four female Wistar rats divided into several groups. After undergoing surgery to simulate menopause, we induced iron accumulation in them. We then treated some groups with Deferasirox at varying doses and looked into its effects on their health.
We observed that the treatment with Deferasirox led to improved conditions in several key areas. There were noticeable positive changes in the uterine tissue, an increase in white blood cells, and a decrease in harmful iron levels. Moreover, the treatment increased the body’s antioxidant capacity, helping fight oxidative stress commonly seen in menopausal conditions.
Deferasirox also had beneficial effects on bone health and the overall functioning of blood-producing cells. Additionally, it influenced gene expressions related to iron metabolism and blood production. Overall, we found that Deferasirox plays an important role in managing iron and enhancing blood health in rats experiencing conditions similar to menopause.
9
Ferritin level increase
Most Useful Review
16 people found this helpful
I started taking iron supplements when my ferritin was in the thirties. After three months, my level rose to the sixties, which I consider effective. I plan to continue taking it since my meals have not been sufficient, especially during menopause.
Anemia details
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.6
USERS' SCORE
Good
Based on 292 Reviews
8
9.5
We examined how iron treatment specifically impacts anemia, particularly during pregnancy. Iron deficiency is a leading cause of anemia, and finding the right treatment is crucial for both mothers and their developing babies.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
Our study focused on just the effects of iron without looking at other treatments. This clear approach allowed us to isolate the benefits of iron supplementation. The results were insightful, showing that iron treatment had measurable effects on reducing anemia.
However, we must be careful about overgeneralizing these findings. While our results indicate improvements, it's important to recognize that individual responses to iron may vary. Our findings highlight the importance of monitoring iron levels in pregnant women to effectively address anemia.
9
Improved hemoglobin
Most Useful Review
618 people found this helpful
I found this iron supplement incredibly effective during my pregnancy when I suffered from anemia. None of the prescribed medications improved my condition. After researching, I discovered that diglycinate is well absorbed. Within three weeks of taking this supplement, my hemoglobin rose from 96 to 123, and my ferritin levels improved from 40 to nearly 90. Unlike earlier medications, I experienced no gastrointestinal issues. I hope my review helps you!
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.7
USERS' SCORE
Good
Based on 34 Reviews
8
8
We explored how iron levels impact depression and hippocampal health. By studying mice under chronic mild stress and using an iron chelator, we observed that excessive iron leads to synaptic damage in the brain. This harmful effect was linked to the downregulation of crucial proteins involved in brain health.
Interestingly, when we activated a protein called Nrf2, we saw improvements in iron balance and a reduction in depression symptoms. Our findings suggest that focusing on Nrf2 and managing iron levels could be key in developing better treatments for depression.
Interestingly, when we activated a protein called Nrf2, we saw improvements in iron balance and a reduction in depression symptoms. Our findings suggest that focusing on Nrf2 and managing iron levels could be key in developing better treatments for depression.
7.5
Improved mood
Most Useful Review
90 people found this helpful
I've been using this vitamin for a few months and my overall well-being has noticeably improved. My mood has enhanced, making it an excellent supplement for those who struggle with depression, as it offers varied health benefits, providing good value for money.
Dizziness details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.8
USERS' SCORE
Good
Based on 163 Reviews
8
9
We studied the impact of iron treatment on dizziness experienced by a 42-year-old woman suffering from severe iron deficiency anemia due to menometrorrhagia. Throughout her hospital stay, she received blood transfusions and intravenous iron, which played a critical role in addressing her debilitating symptoms.
Remarkably, despite her initial critically low hemoglobin levels, she managed to remain hemodynamically stable. By the end of her treatment, her symptoms of fatigue and dizziness had resolved, allowing her to return to her normal activities before discharge. This case highlights an important connection between iron levels and dizziness, illustrating that replenishing iron can significantly alleviate dizzy spells linked to anemia.
Our findings underscore how crucial it is to address iron deficiency effectively, as it can prevent serious complications and improve overall quality of life for patients experiencing symptoms like dizziness.
Remarkably, despite her initial critically low hemoglobin levels, she managed to remain hemodynamically stable. By the end of her treatment, her symptoms of fatigue and dizziness had resolved, allowing her to return to her normal activities before discharge. This case highlights an important connection between iron levels and dizziness, illustrating that replenishing iron can significantly alleviate dizzy spells linked to anemia.
Our findings underscore how crucial it is to address iron deficiency effectively, as it can prevent serious complications and improve overall quality of life for patients experiencing symptoms like dizziness.
8
Dizziness eliminated
Most Useful Review
318 people found this helpful
I experienced very painful periods, constant fatigue, dizziness, and loss of consciousness. My ferritin was significantly low, so I ordered chelated iron. I initially planned to keep it for myself, but my friend, who was pregnant and needed it more, ended up taking it. I felt a marked improvement with no more dizziness or fatigue and my energy levels increased. I plan to repeat the ferritin test soon; compared to previous medications, this has been a fantastic result.
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.5
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.9
9
We investigated the role of iron treatment in managing heart disease, particularly its isolated effects. The research closely looked at how iron supplementation interacts with other therapies in patients with heart conditions.
Heart disease can often be complicated by iron deficiency, leading to questions about the potential benefits of treating this deficiency. Our findings revealed that while iron treatment showed some promise, its overall effectiveness on improving heart disease symptoms or outcomes appeared limited when considered in isolation.
Additionally, the study emphasized the importance of viewing iron treatment not as a standalone solution, but as part of a broader approach that includes other therapies. This nuanced understanding can help guide healthcare practices in treating heart disease patients more effectively.
Heart disease can often be complicated by iron deficiency, leading to questions about the potential benefits of treating this deficiency. Our findings revealed that while iron treatment showed some promise, its overall effectiveness on improving heart disease symptoms or outcomes appeared limited when considered in isolation.
Additionally, the study emphasized the importance of viewing iron treatment not as a standalone solution, but as part of a broader approach that includes other therapies. This nuanced understanding can help guide healthcare practices in treating heart disease patients more effectively.
7.5
Improved energy levels
Most Useful Review
52 people found this helpful
I had been suffering from anaemia, feeling constantly fatigued and with low blood pressure. My ferritin level was shockingly low at 7. After starting on iron supplements, I noticed significant improvements within weeks. My dizziness and low blood pressure improved to 110/70, and my ferritin has increased to 35. I wholeheartedly recommend this product!
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.9
9
Effective rash treatment
Most Useful Review
I ordered this product again upon my dermatologist's recommendation, as the rashes on my skin disappeared. The doctor pointed out it was due to an iron deficiency. Now, this brand is available to my friends and family. While a doctor's advice is essential, I found it incredibly effective for my situation!
Anxiety details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 19 Reviews
7.8
7
We examined how changes in iron levels during pregnancy relate to anxiety and overall wellbeing. The study followed pregnant women in Cape Coast, Ghana, tracking their iron status and psychological health throughout the first, second, and third trimesters.
Our findings indicate that improvements in iron levels from the first to the second trimester significantly reduced anxiety, especially concerning fearful feelings. The numbers showed that women who enjoyed better iron status experienced less anxiety, which suggests iron supplementation might play a helpful role in enhancing mental health during early pregnancy.
However, we also noted that as iron levels changed from the second to the third trimester, there was a surprising rise in anxiety. Despite initial improvements, some aspects of quality of life declined, indicating the complex relationship between iron status and mental wellbeing.
Overall, this study sheds light on the importance of monitoring and managing iron levels in expecting mothers, as it may impact not only physical health but also emotional wellbeing.
Our findings indicate that improvements in iron levels from the first to the second trimester significantly reduced anxiety, especially concerning fearful feelings. The numbers showed that women who enjoyed better iron status experienced less anxiety, which suggests iron supplementation might play a helpful role in enhancing mental health during early pregnancy.
However, we also noted that as iron levels changed from the second to the third trimester, there was a surprising rise in anxiety. Despite initial improvements, some aspects of quality of life declined, indicating the complex relationship between iron status and mental wellbeing.
Overall, this study sheds light on the importance of monitoring and managing iron levels in expecting mothers, as it may impact not only physical health but also emotional wellbeing.
7.5
Anxiety reduction
Most Useful Review
40 people found this helpful
Upon starting this iron supplement, I noticed a warm feeling in my body and relief from anxiety and fatigue. Although I was initially alarmed by the black stools, I learned they are a normal effect of taking iron, which reassured me to continue.
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 49 Reviews
7.8
7
We explored whether iron deficiency anemia is connected to chronic daily headaches in a group of 100 patients compared to an equal number of controls.
The study revealed a significant link between iron deficiency anemia and chronic daily headaches. Interestingly, those with severe anemia experienced more intense headache symptoms.
While other iron-related factors were associated with headaches, the type and duration of headaches did not seem to vary significantly among patients.
The study revealed a significant link between iron deficiency anemia and chronic daily headaches. Interestingly, those with severe anemia experienced more intense headache symptoms.
While other iron-related factors were associated with headaches, the type and duration of headaches did not seem to vary significantly among patients.
9
Gentle on stomach
Most Useful Review
97 people found this helpful
I would definitely purchase these again. I feel much better after taking them. The iron does not upset my stomach or cause headaches. In fact, this supplement has been very gentle on my stomach, avoiding the usual issues I have with iron supplements. I would recommend these to anyone who is uncertain about iron supplements. The price is excellent with double strength composition!
Liver Disease details
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
USERS' SCORE
Moderately Good
Based on 20 Reviews
7.8
9
We explored the effects of rubiadin, a beneficial compound derived from a Chinese herb, on iron metabolism and its implications for liver disease. Recognizing the challenges posed by iron overload diseases, we aimed to discover a safe approach to manage excessive iron accumulation in the body. Through experiments involving various analyses, we observed that rubiadin significantly downregulated proteins that are typically elevated in conditions of high iron, such as transferrin receptor 1 and ferroportin 1.
Furthermore, when we administered rubiadin to mice with iron overload, it resulted in decreased serum and duodenal iron levels and an increase in hepcidin mRNA expression in the liver. This suggests that rubiadin may not only help the body regulate iron better but might also protect against the harmful effects of excess iron.
Our research also delved into the mechanisms behind these effects. We found that rubiadin-induced hepcidin expression was mediated through a specific signaling pathway involving bone morphogenetic protein 6 (BMP6) and SMAD proteins. The ability of rubiadin to enhance hepcidin levels points toward a promising natural strategy for tackling iron overload in liver diseases and could have broader implications for treating related conditions.
Furthermore, when we administered rubiadin to mice with iron overload, it resulted in decreased serum and duodenal iron levels and an increase in hepcidin mRNA expression in the liver. This suggests that rubiadin may not only help the body regulate iron better but might also protect against the harmful effects of excess iron.
Our research also delved into the mechanisms behind these effects. We found that rubiadin-induced hepcidin expression was mediated through a specific signaling pathway involving bone morphogenetic protein 6 (BMP6) and SMAD proteins. The ability of rubiadin to enhance hepcidin levels points toward a promising natural strategy for tackling iron overload in liver diseases and could have broader implications for treating related conditions.
9
Significant improvement
Most Useful Review
391 people found this helpful
Awesome working additive! This iron supplement has notably improved my friend’s condition with liver disease. She struggled with low haemoglobin due to her medications. After taking this iron for three months, her haemoglobin rose significantly! Unlike other treatments, this one didn't cause nausea. She feels great now, and I’ve started it for prevention myself. Many thanks to the manufacturers!
Premenstrual Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 49 Reviews
7.8
9
Reduced PMS symptoms
Most Useful Review
5 people found this helpful
Very effective! When my period comes, drinking a lot helps reduce my PMS; I avoid headaches and feel good. After a year of use, alongside various supplements, I noticed my cold hands and feet have warmed up. My PMS, which worsened with age, has improved; I no longer experience headaches or general malaise, and my symptoms are more manageable.
Uterine Fibroids details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.8
9
Significant symptom relief
Most Useful Review
After transitioning from endometriosis to uterine fibroids and then being diagnosed with uterine adenomyosis, I've undergone treatment. I've managed to stop my periods with medication, but it caused irregular bleeding and anaemia. Since taking this supplement with breakfast, my symptoms have notably improved, reducing my discomfort significantly.
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.7
9
Symptoms have disappeared
Most Useful Review
43 people found this helpful
I can't live without this. During childbirth, I suffered a sore throat and fever monthly and felt desperate after multiple visits to the otolaryngology department. After learning I might be deficient in iron and zinc, I began taking this supplement, and my symptoms vanished. Initially, I tried domestic brands but found they lacked iron, so I switched to Now Foods, which offers far more iron at a better price. Though the smell was initially off-putting, I became accustomed to it over time. I recommend buying from either iHerb or Rakuten, depending on pricing.
Colitis details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.7
9
We investigated the role of dietary iron in recovery from colitis, specifically focusing on its effects in weaned mice. The study involved two groups of mice fed different diets: one with a regular amount of iron and another enriched with significantly more iron. After two weeks on their respective diets, both groups were subjected to dextran sodium sulfate (DSS) treatment to induce colitis.
Throughout the recovery phase, we observed that the iron-enriched diet proved especially beneficial for the weaned mice. By day three of recovery, those on the iron diet showed less weight loss, shorter colon lengths, and less damage to intestinal structure compared to their counterparts. Iron not only promoted the vitality of intestinal stem cells but also helped maintain the integrity of the intestinal lining.
Furthermore, analyses of organoids revealed that the iron diet stimulated the expression of certain genes involved in differentiation and metabolism, which suggests a deeper mechanism at play. Overall, this study indicates that dietary iron may significantly enhance the repair of intestinal injuries and support the regeneration of healthy tissue following inflammation.
Throughout the recovery phase, we observed that the iron-enriched diet proved especially beneficial for the weaned mice. By day three of recovery, those on the iron diet showed less weight loss, shorter colon lengths, and less damage to intestinal structure compared to their counterparts. Iron not only promoted the vitality of intestinal stem cells but also helped maintain the integrity of the intestinal lining.
Furthermore, analyses of organoids revealed that the iron diet stimulated the expression of certain genes involved in differentiation and metabolism, which suggests a deeper mechanism at play. Overall, this study indicates that dietary iron may significantly enhance the repair of intestinal injuries and support the regeneration of healthy tissue following inflammation.
9
Free from anaemia
Most Useful Review
Thank you for taking a large amount of iron. I have ulcerative colitis and experience melena daily, but my doctor doesn’t prescribe iron supplements, so I take three capsules each night. As a result, the previously white eyelids under my eyes are now bright red, and I am free from anaemia. Compared to commercially available heme iron supplements, this allows for a larger intake of iron, is easy to consume, and doesn’t cause stomach pain. I feel that it suits me very well.
Constipation details
SCIENTIFIC SCORE
Questionable
Based on 11 Researches
6
USERS' SCORE
Moderately Good
Based on 220 Reviews
7.7
9
We assessed how iron supplementation impacts blood donors who may suffer from low iron levels. Our analysis included thirty studies with nearly 4,700 participants, focusing on the differences between those receiving iron and those who didn’t.
We found that iron supplements reduced the chances of donors being deferred due to low hemoglobin levels and helped elevate their hemoglobin and iron stores. However, we also noted more side effects, like constipation and nausea, among those taking iron.
These side effects hinder its widespread use, suggesting iron supplements should be targeted to at-risk individuals only.
We found that iron supplements reduced the chances of donors being deferred due to low hemoglobin levels and helped elevate their hemoglobin and iron stores. However, we also noted more side effects, like constipation and nausea, among those taking iron.
These side effects hinder its widespread use, suggesting iron supplements should be targeted to at-risk individuals only.
9
No constipation noted
Most Useful Review
242 people found this helpful
Strength and energy! This hardware is excellent. The quality surpasses what is found in pharmacies. It’s easy to take, doesn’t cause constipation and acts gently on the digestive tract. It's great for boosting haemoglobin levels and restoring energy.
Bone Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.3
USERS' SCORE
Moderately Good
Based on 25 Reviews
7.6
9
Alendronate reduces pain and improves BMD
We explored the effectiveness of alendronate, a common drug for osteoporosis, in treating bone pain and improving bone health in patients with thalassemia. This randomized controlled trial involved men and premenopausal women, who were given either alendronate or a placebo for 12 months.
We found that alendronate significantly improved bone mineral density and reduced back pain. Even better, the treatment was well tolerated with a good safety profile. Overall, our findings suggest that alendronate can be beneficial for those struggling with osteoporosis linked to thalassemia.
We found that alendronate significantly improved bone mineral density and reduced back pain. Even better, the treatment was well tolerated with a good safety profile. Overall, our findings suggest that alendronate can be beneficial for those struggling with osteoporosis linked to thalassemia.
9
Improved wellbeing
Most Useful Review
46 people found this helpful
I'm amazed by the results of this iron supplement! After struggling with low haemoglobin, my doctor recommended it. I opted for a chelative iron that is gentle on the stomach. After a month, my levels rose significantly, and I felt energised without experiencing any bone pain or other side effects. I highly recommend it!
Nausea details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Moderately Good
Based on 86 Reviews
7.6
9
We evaluated how switching to ferric citrate hydrate (FCH) impacts nausea in women with iron deficiency anemia (IDA) who struggled with oral iron. In a multicenter study of 30 patients, those on FCH experienced significant improvements. Nausea scores dropped from 5.7 to 1.7, and the overall incidence of nausea decreased notably. Also, 80% reported better experiences compared to previous treatments.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
Overall, our findings suggest that FCH not only enhances medication adherence but also effectively reduces nausea and improves quality of life in these patients.
9
No nausea
Most Useful Review
391 people found this helpful
Awesome working additive! I ordered this iron for a friend suffering from muscle myositis. She struggled with low haemoglobin and fatigue, trying various pharmacy drugs with nausea as a side effect. After taking this for 3 months, her haemoglobin rose from 117 to 143, and the product caused no nausea. She's feeling great at work now! I also ordered it for myself for preventative measures. Thank you to the manufacturers for such a wonderful product!
Urinary Tract Infection details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.6
8
Iron nanoparticles show promising antibacterial effects
We investigated how iron oxide nanoparticles can combat bacterial infections in the urinary tract. During our study, we analyzed urine samples from elderly patients and identified various bacterial strains causing infections. By synthesizing iron oxide nanoparticles, we tested their effectiveness against these bacteria.
We found that these nanoparticles displayed strong antibacterial activity, particularly against gram-negative bacteria. The minimum inhibitory concentration demonstrated significant results compared to controls, indicating their potential as a novel treatment option. However, results suggested that while effective, iron oxide nanoparticles’ advantages may not be uniform across all bacteria types.
We found that these nanoparticles displayed strong antibacterial activity, particularly against gram-negative bacteria. The minimum inhibitory concentration demonstrated significant results compared to controls, indicating their potential as a novel treatment option. However, results suggested that while effective, iron oxide nanoparticles’ advantages may not be uniform across all bacteria types.
9
Good efficacy
Most Useful Review
3 people found this helpful
The drug really works. It effectively raises iron levels; my haemoglobin increased from 103 to 121 and ferritin from 8 to 27 in about a month! Other preparations only raised haemoglobin, and I was frustrated with the ferritin levels. This iron caused no gastrointestinal side effects, apart from slightly darkened stools. However, after about three weeks of daily intake, I experienced an unpleasant sensation similar to abrupt pressure changes. I then switched to taking it every other day, as it seemed the dosage was too high for frequent use. It's essential to listen to your body when taking this drug.
Hemorrhoids details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.5
7.5
Effective aid
Most Useful Review
My mother has hemorrhoids, so I purchased it for her anaemia. The effect has been positive.
Bloating details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.4
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.4
8
We explored how iron supplementation impacts patients with celiac disease who suffer from iron deficiency anemia, particularly focusing on those unable to tolerate traditional iron sulfate. In this study, patients were divided into two groups: one receiving a new formulation called sucrosomial iron and the other taking iron sulfate.
After a 90-day follow-up, both groups showed significant improvements in hemoglobin levels and overall iron metrics. Interestingly, those taking sucrosomial iron experienced a marked reduction in abdominal symptoms like bloating and pain. They reported feeling a 33% increase in general well-being compared to 21% in the iron sulfate group.
This suggests sucrosomial iron could be a preferable option for individuals with celiac disease who struggle with gastrointestinal discomfort from standard iron treatments. Overall, while both forms of iron supplementation were effective, sucrosomial iron may ease some of the unpleasant side effects commonly associated with iron therapy.
After a 90-day follow-up, both groups showed significant improvements in hemoglobin levels and overall iron metrics. Interestingly, those taking sucrosomial iron experienced a marked reduction in abdominal symptoms like bloating and pain. They reported feeling a 33% increase in general well-being compared to 21% in the iron sulfate group.
This suggests sucrosomial iron could be a preferable option for individuals with celiac disease who struggle with gastrointestinal discomfort from standard iron treatments. Overall, while both forms of iron supplementation were effective, sucrosomial iron may ease some of the unpleasant side effects commonly associated with iron therapy.
9
No bloating experienced
Most Useful Review
1 people found this helpful
After using two cans, my ferritin levels doubled! I continue to take them regularly with no bloating or discomfort. I highly recommend these.
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.8
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.2
4
We explored how low-level iron supplementation impacts the gut microbiota in individuals with Irritable Bowel Syndrome (IBS) and in healthy donors. To do this, we conducted anaerobic, pH-controlled in vitro batch cultures using fecal samples from both groups, supplemented with various forms of iron, including ferrous sulphate, nanoparticulate iron, and pea ferritin.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
Our findings revealed that IBS participants had distinct microbial profiles compared to their healthy counterparts. Interestingly, we observed that the different sources of iron we used did not have a negative effect on the overall microbial populations. Both pea ferritin and nanoparticulate iron showed similar outcomes, while ferrous sulphate appeared to enhance certain beneficial bacteria.
Additionally, we measured the production of metabolites and found that there was no harmful shift towards increased proteolysis. These results suggest that low doses of iron from the three sources tested are unlikely to be detrimental to the gut microbiota, giving us new insights into the potential for iron supplementation in managing gut health, especially for those with IBS.
This is the first time we've tested fermentation of pea ferritin, which adds an exciting dimension to our understanding of dietary iron sources and gut health.
9
No discomfort noted
Most Useful Review
32 people found this helpful
Excellent iron dosage! I take it with vitamin C. This iron is very gentle; my digestive tract has experienced no discomfort, only darker stools. It’s a great product at a low price with excellent quality, and my bowels function well while taking this supplement.
Candidiasis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 8 Reviews
6.5
9
No side effects
Most Useful Review
Iron bisglycinate is an excellent form of iron as it doesn't cause side effects or aggravate Candida. I have found it effective for raising iron levels, especially when taken with vitamin C, making it a beneficial supplement without the unwanted complications.
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Medium or Average
Based on 7 Reviews
6.4
9
Magnetic stent-grafts improve healing
We explored how magnetizable stent-grafts can improve healing in carotid artery pseudoaneurysms by investigating their ability to capture blood outgrowth endothelial cells.
In a porcine model, we compared magnetic stent-grafts with standard non-magnetic ones. The results showed that the magnetic stent-grafts not only occluded all nine pseudoaneurysms but also achieved better cell capture and endothelial growth.
Essentially, the magnetic properties enhanced the healing process, leading to less thrombosis compared to non-magnetic counterparts. This innovative approach could reduce complications associated with these medical devices.
In a porcine model, we compared magnetic stent-grafts with standard non-magnetic ones. The results showed that the magnetic stent-grafts not only occluded all nine pseudoaneurysms but also achieved better cell capture and endothelial growth.
Essentially, the magnetic properties enhanced the healing process, leading to less thrombosis compared to non-magnetic counterparts. This innovative approach could reduce complications associated with these medical devices.
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