NOW Supplements Vitamin E 1000 IU

Curcumin and vitamin E improve hot flashes, lipid profile, and fasting blood glucose without any detrimental effect on the liver and renal function in postmenopausal women: A triple-blind placebo-controlled clinical trial.

Most Relevant Research

We conducted a study with eighty-four postmenopausal women to see how vitamin E affects hot flashes, among other health markers. The participants were divided into three groups and received either Vitamin E, Curcumin, or a placebo for eight weeks.

Our findings revealed that vitamin E significantly reduced the frequency of hot flashes by nearly one-third compared to those taking the placebo. This reduction was accompanied by improvements in several health indicators, including lower serum triglyceride levels and enhanced high-density lipoprotein (HDL) cholesterol.

Furthermore, vitamin E also showed positive effects on liver health markers. Overall, it appears that vitamin E is effective not only in alleviating hot flashes but also in improving some aspects of the lipid profile in postmenopausal women, without adverse effects on liver or kidney function.

9.5

Complete relief

Most Useful Review

Stopped my hot flashes. I've tried other products, but this and Carlson's Key-E suppositories (which contain Vitamin E) are what stopped my hot flashes. Occasionally, I feel a bit flushed if I forget to use either, but I haven’t had a serious episode in months. It may not work for everyone, but it is a relief for me.

Leg Cramps

Vitamin E's potential in leg cramps

Are there alternatives to the use of quinine to treat nocturnal leg cramps?

Most Relevant Research

We explored the potential role of vitamin E in treating leg cramps, particularly in populations such as those undergoing dialysis. The study aimed to understand if vitamin E could provide relief from troublesome nocturnal leg cramps—an issue that many individuals face.

While the effects of quinine, a common treatment, have been closely scrutinized, vitamin E emerges as a noteworthy alternative. Although large-scale randomized controlled trials focusing specifically on vitamin E for leg cramps are limited, some data suggest that it may hold promise for alleviating symptoms. This is especially true for those who might not respond to other treatments.

We observed that incorporating vitamin E could be a safer option, as this supplement generally has a more favorable safety profile compared to quinine. However, it's important to underscore that patients should consider exploring other treatments before turning to quinine, particularly given the latter's potential side effects.

9.5

Relief from cramps

Most Useful Review

I have two each day and I no longer experience any menstrual cramps.

Ameliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopause-associated mood disorder in ovariectomized mice.

Most Relevant Research

We explored the effects of vitamin E on anxiety and depression, particularly in the context of menopause-related mood disorders. To conduct this research, we studied ovariectomized mice—an animal model representing estrogen deficiency.

Our findings indicated that ovariectomized mice exhibited behaviors linked to depression and anxiety. Notably, these mice had higher levels of corticosterone, a hormone that signals stress, compared to a control group. We observed that administering α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract significantly reduced these mood disturbances over a two-week period.

While both treatments helped alleviate anxiety and depressive behaviors, tocotrienol-rich palm oil extract showed a more pronounced effect, particularly in mice under chronic stress. Additionally, both forms of vitamin E were effective in lowering elevated corticosterone levels, suggesting that they may help modulate the body’s stress response.

Overall, our research supports the potential of vitamin E as a promising treatment for mood disorders associated with menopause, highlighting its role in improving psychological well-being.

9.5

Supports logical thinking

Most Useful Review

Great for Depression! This is the only thing that helps with my depression. I've always suffered from anxiety and depression, sometimes so crippling that getting out of bed was a challenge. This supplement helps me think clearly and get out of bed. I never miss my daily dose, taking 1200mg to manage my depression and 1600mg during stressful times.

Breast Cancer

Excellent antioxidant effects

Most Useful Review

Excellent Vitamin E! This supplement is a superb antioxidant. I take one capsule daily after breakfast to tackle cysts and support my breast cancer treatment. The soft capsules are easy to swallow, although they smell a bit fishy when opened. I even use the oil on my lips at night to combat dryness. Highly recommend!

Chronic Fatigue Syndrome

Improved blood circulation

Most Useful Review

I recommend this supplement for replenishing significant amounts of Vitamin E. It contains natural d-α tocopherol with strong antioxidant effects, alongside other tocopherols, reducing the risk of deficiency. Although the pills are larger than 400IU options, I became accustomed to them. This supplement alleviates my chronic fatigue syndrome and improves blood circulation.

Frozen Shoulder

Improved blood circulation

Most Useful Review

Heart Attack

Improved heart health

Most Useful Review

Cardiovascular Maintenance has greatly improved my blood pressure after several weeks of use. Alpha tocopherol is highly effective and benefits my overall heart health significantly, which is essential in reducing the risk of heart attack.

High Cholesterol

I chose this product for its high E content. I only need to take one a day, and it’s beneficial for my heart health.

Menopause

SCIENTIFIC SCORE

Moderately Effective

Based on 3 Researches

Vitamin E enhances vaginal health

Retrospective Investigator-Initiated Trial on Tocopherol Acetate Vaginal Administration in Pre-and Postmenopausal Women.

Most Relevant Research

We examined how tocopherol acetate, commonly known as vitamin E, affects vaginal health in women experiencing menopause and those who are premenopausal. The study involved 50 women, split into two groups: 28 postmenopausal and 22 premenopausal, who were assessed before and after a two-week treatment with tocopherol acetate ovules.

After the treatment period, we observed significant improvements in the bothersome symptoms associated with vaginal atrophy, such as dryness, itching, and discomfort during intercourse. Participants reported a noticeable difference in their vaginal health post-treatment, which is quite encouraging. Additionally, a molecular analysis indicated a positive change in the vaginal microbiota, particularly among the premenopausal group, suggesting that vitamin E can help foster a healthier vaginal environment.

Overall, our findings support the potential benefits of using tocopherol acetate for enhancing vaginal well-being during menopause. This could offer a natural alternative for women seeking relief from menopausal symptoms, improving their quality of life during this transitional phase.

8.8

Positive effects noted

Most Useful Review

Good! It’s large but easy to consume. Based on Fujikawa's theory, vitamins C and E are beneficial for PMS. I've been feeling unwell during menopause, so I started taking this in hopes of improvement. I take 2000 IU each morning, making this a better option than E-400.

Osteoporosis

My wife takes the Now E-1000 to aid in treating her osteoporosis. One a day has maintained her health effectively.

Sleep Apnea

It has had a noticeable effect. I consume it with various dishes. I now feel much better and sleep more soundly. It is a high-quality product.

Acne

SCIENTIFIC SCORE

Questionable

Based on 16 Researches

No significant benefit of vitamin E

Vitamin E does not reduce the side-effects of isotretinoin in the treatment of acne vulgaris.

Most Relevant Research

We explored the effectiveness of vitamin E alongside isotretinoin, a common treatment for severe acne. In an investigator-blinded, randomized study involving 82 patients, participants were divided into two groups. One group received isotretinoin alone, while the other combined it with 800 IU of vitamin E, over a period of 16 weeks.

Our main goal was to determine whether vitamin E could reduce the side-effects associated with isotretinoin, which are often bothersome for patients. Throughout the study, we assessed various mucocutaneous side effects, such as facial dryness and redness, as well as changes in serum lipid and liver enzyme levels.

Ultimately, we found no significant difference in the incidence or severity of side effects between the two treatment groups. This indicates that vitamin E did not provide any noticeable benefit when added to isotretinoin therapy for acne vulgaris.

While vitamin E is often suggested as a remedy to lighten the side effects of medications, our findings suggest that its use alongside isotretinoin may not be helpful.

8.8

Tremendous acne help

Most Useful Review

I bought these along with three other NOW vitamins to help with my acne. All of them combined have helped tremendously. It took about three weeks for results, so if you're looking for something to help with acne, use them all and give them some time.

Skin Cancer

After a cancer diagnosis, I started taking an E vitamin, which is significantly curable. I found Vitamin E to be a potent antioxidant. A few weeks later, I noticed remarkable improvements in my skin. I didn't realise it required enhancement until I saw the difference.

Cancer

SCIENTIFIC SCORE

Moderately Effective

Based on 9 Researches

Gamma-tocopherol in cancer research

Gamma-Tocopherol: A Comprehensive Review of Its Antioxidant, Anti-Inflammatory, and Anticancer Properties.

Most Relevant Research

We examined the effects of gamma-tocopherol, a major form of vitamin E, on cancer treatment and prevention. This powerful antioxidant is noted for its ability to combat oxidative stress, which plays a significant role in the development and progression of various cancers.

In several studies, we observed that gamma-tocopherol not only neutralizes harmful reactive oxygen species but also exhibits anti-inflammatory properties. These characteristics help reduce chronic inflammation tied to cancer risks. Furthermore, it has shown the potential to inhibit tumor growth, induce cancer cell death, and restrict blood vessel formation that tumors require to grow.

Specifically, findings indicated that gamma-tocopherol is particularly effective in cancers such as prostate, lung, and colon. With promising results from both preclinical and clinical trials, there is a growing interest in how this natural compound can be beneficial in cancer management.

While we noted excellent tolerance at normal doses, it’s essential to consider careful monitoring at higher levels to avoid any adverse effects. Hence, we believe that ongoing research and advancements in drug delivery methods could further enhance its effectiveness.

Antioxidant effect

Most Useful Review

It is a good supplement. The body tends to oxidise, leading to the unpleasant odour of ageing, but vitamin E provides an antioxidant effect. I recommend it for middle-aged individuals facing stress. Moreover, since cancer cells dislike antioxidants, this supplement could also assist in preventing cancer.