Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Milk Thistle extract (seed) standardized to 80% silymarin (140 mg)
175 mg
**
The product is found useful for the following medical conditions
Hepatitis details
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Good
Based on 5 Reviews
8.7
8
We explored the potential of intravenous silibinin, a milk thistle extract, in treating an HIV-HCV coinfected patient who didn't respond to standard therapy. After just two weeks of silibinin treatment, both HCV and HIV levels became undetectable.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
While silibinin appeared promising, leading to a trend of increased CD4+ cells, the follow-up showed that HIV levels returned to their previous state after stopping additional therapy.
These findings suggest that while silibinin may help some, more research is needed to understand its benefits fully.
9
Therapeutic benefits
Most Useful Review
32 people found this helpful
This product is incredibly safe and offers unmatched protection for the liver. Clinical studies indicate that standardized milk thistle, particularly in doses of around 600 mg, can improve conditions such as alcohol-related liver disease, hepatitis, and liver cirrhosis over 8-12 weeks. It’s essential to consult a physician before use, but this product is both beneficial and safe while taking prescriptions.
Updated: Mar 2026
Acne details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
We explored the effects of Silybum marianum fruit extract on acne treatment using a topical formulation over 48 weeks in a group of acne patients. The study identified microcomedones, which are early signs of future acne lesions, as a target for prevention.
Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
Our findings revealed that using the extract significantly lowered the microcomedone index in patients, indicating a reduction in acne severity. The improvement in microcomedones closely tied to a decrease in clinical lesions suggests that Silybum marianum may be a promising option for maintaining clearer skin and preventing future breakouts.
9
Cleared back acne
Most Useful Review
1 people found this helpful
Cured acne on back. This product helped clear up acne on my back. I am very pleased with it and will be purchasing more.
Updated: Apr 2025
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.1
USERS' SCORE
Good
Based on 4 Reviews
8.4
9
We investigated how silybin, a unique flavonoid found in certain plants, impacts autoimmune disorders, specifically using a model for multiple sclerosis called experimental autoimmune encephalomyelitis (EAE).
In our study, silybin significantly reduced disease severity, inflammation, and damage to the central nervous system (CNS) in EAE mice.
The findings suggest that silybin works by inhibiting the activation of dendritic cells and reducing harmful Th17 cell differentiation. This positions silybin as a promising candidate for new treatments aimed at autoimmune diseases like multiple sclerosis.
In our study, silybin significantly reduced disease severity, inflammation, and damage to the central nervous system (CNS) in EAE mice.
The findings suggest that silybin works by inhibiting the activation of dendritic cells and reducing harmful Th17 cell differentiation. This positions silybin as a promising candidate for new treatments aimed at autoimmune diseases like multiple sclerosis.
9
Improve digestion
Most Useful Review
1 people found this helpful
Following my doctor’s advice, I ordered this product to enhance my gastrointestinal function alongside other liver and bile treatments. After just a week, my digestive system has improved significantly, with better regularity and reduced liver colic pain. I plan to complete the full course for even greater results.
Updated: Mar 2026
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.9
7.5
Positive changes noted
Most Useful Review
3 people found this helpful
I’ve been taking this in hope of alleviating my chronic fatigue syndrome. As a vegetarian, I avoid alcohol and tobacco, yet I noticed a significant change; my lip colour brightened after a few days of use. I'm optimistic about continuing with this product.
Updated: Mar 2026
High Cholesterol details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.6
9
Silymarin positively influences cholesterol
We conducted a triple-blinded randomized clinical trial with 40 type 2 diabetes patients to see how silymarin impacts cholesterol and blood sugar levels. Over 45 days, participants received either silymarin or a placebo.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
Our findings showed that those taking silymarin experienced significant improvements. They had lower fasting blood sugar, reduced triglycerides, and improved levels of good HDL cholesterol.
However, while the results are promising, further research is necessary to confirm these benefits for managing cholesterol in diabetes patients.
7.5
Supports liver health
Most Useful Review
15 people found this helpful
A superb product for a healthy liver. Milk thistle, the primary ingredient, helps to lower LDL (bad) cholesterol levels and reduce insulin resistance. It also serves as an excellent antioxidant, antiviral, and anti-inflammatory aid.
Updated: Mar 2026
Liver Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Moderately Good
Based on 46 Reviews
7.6
9
We investigated the effects of silymarin on liver and heart health under oxidative stress from paracetamol. In a controlled study with 28 male mice, silymarin showed a strong potential to reduce liver injury markers and improve liver enzyme levels after treatment.
Histopathological assessments revealed less tissue damage and inflammation in mice treated with silymarin compared to those that only received paracetamol. Overall, these findings demonstrate that silymarin is a promising option to help protect the liver and heart from oxidative stress-related injury.
Histopathological assessments revealed less tissue damage and inflammation in mice treated with silymarin compared to those that only received paracetamol. Overall, these findings demonstrate that silymarin is a promising option to help protect the liver and heart from oxidative stress-related injury.
9
Supports liver health
Most Useful Review
23 people found this helpful
The best product for maintaining a healthy liver! Milk Thistle, standardised to 80% Silymarin, in doses of around 600 mg per day provides therapeutic benefits, especially for liver disease conditions like alcohol-related liver disease and Hepatitis. It's crucial to consult a qualified physician for serious conditions. Standardised Milk Thistle is highly beneficial for those on prescription drugs or exposed to environmental toxins. I have used Nature's Way for five years, and although I believe they are top-notch, I often opt for Swanson due to its affordability. I take 3-4 capsules daily on an empty stomach to support my liver health.
Updated: Mar 2026
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