New Chapter Fermented Zinc Complex
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Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Zinc (as zinc oxide from ferment media)
15 mg
136%
Copper (as copper sulfate anhydrous from ferment media)
1.5 mg
167%
Cardio Support BlendOrganic Oregano (leaf) from ferment media, Organic Hawthorn (berry, leaf and flower) from ferment media, Grape Seed extract
12 mg
Immune System Blend (from ferment media)European Elder (berry) extract, OrganicEleuthero (root), Organic Astragalus (root)
11.2 mg
Digestive Support Blend (from ferment media)Organic Aloe (leaf), Organic Peppermint (leaf),Organic Coriander (seed), Organic Cardamom (fruit),Organic Artichoke (leaf)
11.2 mg
Ginger (rhizome) 1.2 mg aqueous extract and0.3 mg organic supercritical extract
1.5 mg
Organic Turmeric (rhizome)1 mg from ferment media and 0.3 mg supercritical extract
1.3 mg

The product is found useful for the following medical conditions

Nausea details

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
5.5
USERS' SCORE
Good
Based on 8 Reviews
8.9
7
Zinc treatment reduces nausea risk
Randomized, multicenter, active-controlled open-label study of NPC-25, zinc histidine hydrate, (non-inferiority to NOBELZIN™, zinc acetate dihydrate) for patients with hypozincemia.
Most Relevant Research
We conducted a study to evaluate how effective NPC-25, a new form of zinc, is compared to a well-known treatment, NOBELZIN™, for patients with low zinc levels. Participants in this trial had their zinc levels checked and were grouped to receive either NPC-25 or NOBELZIN™.

For a period of up to 24 weeks, we aimed to maintain their zinc levels within a specific target range while closely monitoring for side effects. One of our main goals was to see if NPC-25 could maintain these target zinc levels similarly to NOBELZIN™.

Our findings revealed that NPC-25 was indeed non-inferior to NOBELZIN™, meaning it worked just as well. Importantly, we also observed that those taking NPC-25 reported fewer digestive issues, like nausea and vomiting. This suggests that while both treatments were effective, NPC-25 might be the gentler option.
10
No nausea experienced
Most Useful Review
Effective and does not cause nausea like most Zinc supplements. I have a zinc deficiency and must take these tablets daily for life. Previously, I took other forms of Zinc that caused severe nausea and discomfort, especially on an empty stomach. This product has been life-changing, allowing me to take my full daily dose without the previous fear of nausea.

Autoimmune Disorder details

SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.5
USERS' SCORE
Good
Based on 4 Reviews
8.8
9
Zinc supplementation benefits MS models
Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model.
Most Relevant Research
We explored how dietary zinc levels influence spinal cord damage and gene expressions associated with Multiple Sclerosis (MS) using a cuprizone-induced rat model. The study included 46 adult male Wistar rats divided into five groups, with some receiving zinc supplementation while others followed a zinc-deficient diet.

After eight weeks of treatment, we found that the rats with MS symptoms showed elevated markers of tissue damage and inflammation, particularly in the groups that lacked zinc. Notably, those receiving zinc supplementation exhibited significantly reduced levels of harmful substances, bringing them back closer to control levels.

Our findings highlight zinc's protective effects in a model of MS, suggesting that incorporating zinc into treatment plans could help alleviate some symptoms associated with this autoimmune disorder. This is promising for future treatment strategies for those affected by MS.
9.5
Nausea-free Zinc
Most Useful Review
I suffer from Acrodermatitis Enteropathica, a rare autoimmune disorder requiring daily Zinc supplementation. This product has been a life changer, as it does not cause nausea, allowing me to take my required dosage without fear, maintaining my Zinc levels effectively.

Yeast Infection details

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9.3
USERS' SCORE
Good
Based on 4 Reviews
8.7
9.5
Zinc's potential against yeast infections
Understanding the nanoscale adhesion forces between the fungal pathogen and antimicrobial zinc-based layered double hydroxides using single-cell and single-particle force spectroscopy.
Most Relevant Research
We explored the effects of zinc-based treatments on yeast infections, particularly focusing on the interaction between zinc-aluminum layered double hydroxides (ZnAl LDHs) and the yeast pathogen. Previous concerns regarding antifungal resistance have prompted the search for new treatments, and our study investigates how these zinc compounds might help.

Through careful experimentation, we used atomic force microscopy (AFM) to observe how ZnAl LDH nanoparticles interacted with yeast cells at a very small scale. Our results showed that these nanoparticles not only had visible antifungal properties but also caused significant damage to the yeast cell walls.

The force measurements revealed strong adhesive interactions between the zinc compounds and the yeast cells, implying that these interactions may play a crucial role in the antifungal activity. In contrast, control substances showed little to no adhesion, underscoring the unique properties of zinc-based treatments.

Overall, our findings suggest a promising avenue in the fight against yeast infections, showing how zinc could help bind to and damage fungal pathogens. It’s an exciting development that offers hope in tackling persistent antifungal resistance issues.
9.5
Great immune boost
Most Useful Review
This is the best zinc product available. It contains copper, curcumin, and fermented ingredients. The composition is completely organic, although yeast is included. There are no gastrointestinal side effects or reactions. I am thrilled with it! This complex is excellent for immunity, with antiviral and antifungal benefits. It has improved my digestive tract functioning due to its enzymes. The effects are remarkable; fatigue vanished within a week, and I've regained significant energy. My hair and nails have improved, and while it makes my skin slightly drier, this suits me, as I can adjust how often I take it. Very effective!

Cold details

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 4 Reviews
8.7
8
Zinc’s effects on colds
Zinc for prevention and treatment of the common cold: Summary of a Cochrane review.
Most Relevant Research
We explored how zinc might help in treating and preventing the common cold. The study focused on zinc's effects, isolating it from other treatments to understand its true impact on cold symptoms. By doing this, the researchers aimed to clarify whether zinc could genuinely shorten the duration of a cold or alleviate its symptoms.

The findings were intriguing but showed that zinc might not yield significant benefits for everyone. While some individuals reported a slight reduction in cold symptoms, the evidence did not strongly support zinc as an effective treatment overall.

This means that, for those seeking relief from a nasty cold, zinc alone might not be the go-to solution we hoped it would be. It’s essential to consider this information when deciding on a cold treatment plan and to approach zinc with realistic expectations.
9.5
Knocks out colds
Most Useful Review
A must when a cold is afoot. It helps to knock out my colds and shortens their duration. A must-have!

Chronic Cough details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Prevented illness
Most Useful Review
I took these zinc supplements consistently before travelling internationally, where the flu was prevalent. Despite being surrounded by people sneezing and coughing, I never fell ill. I have an autoimmune condition and rely on injections for psoriatic arthritis. I trust New Chapter for their whole food-derived products and will never be without zinc again. They are of good quality and of average size, suitable for me.

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.9
USERS' SCORE
Good
Based on 3 Reviews
8.6
7
Zinc supplementation may benefit CFS
Lower serum zinc in Chronic Fatigue Syndrome (CFS): relationships to immune dysfunctions and relevance for the oxidative stress status in CFS.
Most Relevant Research
We explored the relationship between serum zinc levels and chronic fatigue syndrome (CFS) in a study that compared patients with CFS to normal volunteers. By using an atomic absorption method, we measured serum zinc concentrations and found that those suffering from CFS had significantly lower levels of zinc compared to healthy individuals.

Interestingly, we observed a trend indicating that lower zinc levels correlated with greater CFS severity. Patients also reported a negative correlation between their zinc levels and their subjective experiences of infection. This suggests that zinc plays a role in the immune dysfunction commonly seen in CFS.

Furthermore, we noted that lower serum zinc was associated with higher levels of inflammatory markers and certain defects in the early activation of T cells. Since zinc acts as a potent antioxidant, our findings indicate that CFS is linked to increased oxidative stress in these patients. Given this, it may be beneficial for some CFS patients to consider zinc supplements as part of their treatment approach.
9.5
Energy boost
Most Useful Review
This zinc is fantastic! The effect is superb; within a week, my chronic fatigue syndrome improved significantly, and I gained a lot of strength. Not only did my hair stop falling out, but its quality also noticeably enhanced, with plenty of new young hair growing.

Bone Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
8.8
Improvement noted
Most Useful Review
I found this drug effective for my deficiency. Combined with l-tyrosine, it significantly improved my mood and alleviated bone pain, as well as cramps in my legs. I've noticed a reduction in premature greying too. I take it in courses as recommended.

Cold Sores details

SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.2
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Zinc cream alleviates cold sores
A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine.
Most Relevant Research
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.

Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.

As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
9.5
Effective remedy
Most Useful Review
This cool brand offers zinc combined with manganese, and it’s naturally fermented with numerous organic certifications. At the first sign of a cold, I take a pill and feel all symptoms vanish remarkably. During the cold season, I complete a one-month course. I wholeheartedly recommend it.

Sleep Apnea details

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
Zinc protects heart function in OSA
Zinc Is Indispensable in Exercise-Induced Cardioprotection against Intermittent Hypoxia-Induced Left Ventricular Function Impairment in Rats.
Most Relevant Research
We explored how zinc affects heart function in the context of obstructive sleep apnea (OSA), specifically focusing on cases of intermittent hypoxia (IH). In a detailed study using male rats, researchers set up different groups: a control group and one that underwent 10 weeks of exercise training. Half of the rats in both groups were exposed to IH conditions to simulate the effects of sleep apnea.

The results were eye-opening. Rats that experienced IH showed notable impairment in their heart's left ventricular function, characterized by reduced ejection fraction and increased inflammation. However, when treated with zinc, these negative effects were significantly countered. Notably, those who exercised and received zinc treatment displayed improved heart function and antioxidant capabilities compared to their counterparts that did not receive zinc.

On the flip side, exercise alone did not provide the same protective benefits when zinc was absent. The findings suggest that zinc is essential not only for the heart's protection against the damaging effects of IH but also enhances the benefits of physical exercise. This research indicates the importance of zinc in potentially managing heart health in individuals suffering from sleep apnea.
8
Improved sleep
Most Useful Review
Is good. I'm reiterating that I feel less fatigued and sleep better.

Acne details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
USERS' SCORE
Good
Based on 3 Reviews
8.3
8
Zinc effective for acne treatment
Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis.
Most Relevant Research
We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.

Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.

Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
9.5
Significant skin improvement
Most Useful Review
A true game changer for my skin! It has significantly improved my condition and helped my acne. I highly recommend it!
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