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Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
10 mcg (400 IU)
50%
The product is found useful for the following medical conditions
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.7
9
Vitamin D3 modulates autoimmune response
Vitamin D3 attenuates autoimmune thyroiditis by regulating Th17/Treg cell differentiation via YAP/JAK1/STAT1 axis.
Most Relevant Research
We explored how Vitamin D3 impacts autoimmune thyroiditis, a specific autoimmune disorder. In this study, researchers established a mouse model of experimental autoimmune thyroiditis (EAT) to see how Vitamin D3 could influence this condition. After eight weeks of treatment, they assessed thyroid health and immune response through various methods, including staining tissues and measuring hormone levels.
Our observations revealed that administering Vitamin D3 helped reduce damage to the thyroid and decreased the presence of inflammatory cells within the thyroid. This treatment also led to lower levels of thyroid hormones and autoimmune antibodies in the blood, highlighting its positive effect on thyroid function. Additionally, Vitamin D3 appeared to promote the regulatory T cell (Treg) subset while decreasing the levels of Th17 cells, which are often involved in autoimmune processes.
Mechanistically, the study found that Vitamin D3 triggered specific pathways that influence Treg cell activity and survival. Notably, it activated a signaling pathway involving YAP and JAK/STAT, which are crucial for immune cell regulation. These findings suggest that Vitamin D3 could play a significant role in balancing immune responses in autoimmune thyroiditis, making it a promising candidate for further research and potential treatment strategies.
Our observations revealed that administering Vitamin D3 helped reduce damage to the thyroid and decreased the presence of inflammatory cells within the thyroid. This treatment also led to lower levels of thyroid hormones and autoimmune antibodies in the blood, highlighting its positive effect on thyroid function. Additionally, Vitamin D3 appeared to promote the regulatory T cell (Treg) subset while decreasing the levels of Th17 cells, which are often involved in autoimmune processes.
Mechanistically, the study found that Vitamin D3 triggered specific pathways that influence Treg cell activity and survival. Notably, it activated a signaling pathway involving YAP and JAK/STAT, which are crucial for immune cell regulation. These findings suggest that Vitamin D3 could play a significant role in balancing immune responses in autoimmune thyroiditis, making it a promising candidate for further research and potential treatment strategies.
9.5
Improved immunity
Most Useful Review
Strengthening my immune system has been fantastic! I had a deficiency of vitamin D, but after taking it continuously, I've noticed significant improvements in my immune system, a reduction in hair loss, and my nails are in excellent condition. When I stop taking vitamin D, I feel persistently tired. Now, with levels at 65.86 ng/mol, I'm very pleased with the results and recommend it.
Cold Sores details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.7
9.5
Miracle vitamin
Most Useful Review
If I had known earlier how this miracle vitamin could combat colds and flu, I would have taken it sooner. Vitamin D3 is an incredible prohormone that strengthens bone structure and protects against viruses, bacteria, and fungi. I’ve recommended it to everyone.
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.7
8
Vitamin D3 aids cold recovery
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
Most Relevant Research
We explored how 25-hydroxyvitamin D3 (25OHD), a form of vitamin D, influences upper respiratory tract infections (URTIs), commonly known as colds. In a carefully designed clinical study, we followed 428 participants aged 45 to 74 over a 16-week period. They were randomly assigned to receive either 10 μg of 25OHD daily or a placebo, all while maintaining a double-blind setup to ensure accurate results.
Our findings revealed that those who took 25OHD had reduced duration and severity of their cold symptoms. Participants reported improvements in their overall quality of life during the bouts of URTI. By tracking the health of the participants through surveys designed to measure cold symptoms, we gathered valuable data that indicates vitamin D3 could play a helpful role in managing colds.
This suggests that incorporating vitamin D3 into our diets may be beneficial when we catch a cold, potentially leading to a quicker recovery. It’s a promising avenue for anyone looking to ease the discomfort and duration of these frustrating infections.
Our findings revealed that those who took 25OHD had reduced duration and severity of their cold symptoms. Participants reported improvements in their overall quality of life during the bouts of URTI. By tracking the health of the participants through surveys designed to measure cold symptoms, we gathered valuable data that indicates vitamin D3 could play a helpful role in managing colds.
This suggests that incorporating vitamin D3 into our diets may be beneficial when we catch a cold, potentially leading to a quicker recovery. It’s a promising avenue for anyone looking to ease the discomfort and duration of these frustrating infections.
10
No colds since
Most Useful Review
NOW Foods Vitamin D is a must-have for cold sufferers. My item arrived on time, and the seller was professional. Since I started taking these vitamin D tablets, I haven’t had a cold. I love the taste and would recommend them to family and friends suffering from colds.
Flu details
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
6.5
USERS' SCORE
Good
Based on 2 Reviews
8.7
8
Vitamin D3 reduces flu incidence
Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren.
Most Relevant Research
We carried out a study to investigate whether vitamin D3 supplements could help prevent seasonal influenza A in schoolchildren. Our approach involved a randomized, double-blind, placebo-controlled trial conducted from December 2008 to March 2009.
This ensured that neither the participants nor the researchers knew who was receiving the vitamin D3 or the placebo, making our findings more reliable. During the trial, we provided 1200 IU of vitamin D3 daily to one group while the other received a placebo.
The results were promising; we found that only 10.8% of the children taking vitamin D3 contracted influenza A, compared to 18.6% in the placebo group. This reduced incidence led us to a relative risk of 0.58, suggesting that vitamin D3 supplementation may lower the chances of getting the flu.
Interestingly, we noticed the most significant benefits among children who hadn’t been taking any other vitamin D supplements and those who began nursery school after age three. Additionally, in children with a past asthma diagnosis, vitamin D3 seemed to dramatically reduce asthma attacks.
Overall, our findings indicate that taking vitamin D3 in the winter could be beneficial for schoolchildren, especially for certain groups. We believe this study adds valuable insights into preventive health measures against influenza A.
This ensured that neither the participants nor the researchers knew who was receiving the vitamin D3 or the placebo, making our findings more reliable. During the trial, we provided 1200 IU of vitamin D3 daily to one group while the other received a placebo.
The results were promising; we found that only 10.8% of the children taking vitamin D3 contracted influenza A, compared to 18.6% in the placebo group. This reduced incidence led us to a relative risk of 0.58, suggesting that vitamin D3 supplementation may lower the chances of getting the flu.
Interestingly, we noticed the most significant benefits among children who hadn’t been taking any other vitamin D supplements and those who began nursery school after age three. Additionally, in children with a past asthma diagnosis, vitamin D3 seemed to dramatically reduce asthma attacks.
Overall, our findings indicate that taking vitamin D3 in the winter could be beneficial for schoolchildren, especially for certain groups. We believe this study adds valuable insights into preventive health measures against influenza A.
9.5
Vitamin D improvement
Most Useful Review
Love it! I need sublinguals due to severe digestive issues. Most vitamins cause extreme flushing for me, but these are gentler. After three months of use, my Vitamin D level improved from a 7 to 30, crucial for my recovery, alongside a better diet.
Common Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.4
USERS' SCORE
Good
Based on 14 Reviews
8.6
8
Vitamin D3 improves cold symptoms
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
Most Relevant Research
We conducted a thorough investigation into how 25-hydroxyvitamin D3, commonly referred to as vitamin D3, impacts upper respiratory tract infections (URTIs), particularly the common cold. This study was carried out as a randomized, double-blind, placebo-controlled trial, engaging 428 participants, all aged between 45 and 74, across three clinics in Japan.
Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.
Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.
Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
9.5
Prevented colds
Most Useful Review
If I’d known this miraculous vitamin could combat the common cold so effectively, I would have started much earlier. It’s a powerful protector against viruses and bacteria. I recommend it to everyone; it should be a staple in every household.
Pneumonia details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.6
9
Enhanced immunity support
Most Useful Review
Physicians recommend D3 for its benefits, including increased calcium absorption, immunity enhancement, and lower infection risks associated with pneumonia. This product is high quality, and I recommend it to anyone in need.
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Symptoms resolved
Most Useful Review
Effective and good low dosage. My husband was having head rashes during winter and spent all his time indoors. Once he began taking this Vitamin D, his symptoms ceased. Since Vitamin D can accumulate in the body, it’s advisable to opt for a lower dosage.
Asthma details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
Vitamin D3 improves asthma control
Vitamin D supplementation decrease asthma exacerbations in children: a systematic review and meta-analysis of randomized controlled trials.
Most Relevant Research
We explored the effectiveness of vitamin D3 in reducing asthma exacerbations among children through a systematic review and meta-analysis of randomized controlled trials. In our investigation, we analyzed data from ten studies, which included a total of 1,243 children with asthma. Among these, 631 received vitamin D3 supplementation while 612 were given a placebo.
Our pooled analysis revealed promising results: vitamin D3 supplementation significantly reduced the overall number of asthma exacerbations. Specifically, we found a risk ratio of 0.62, indicating a notable decrease in attacks. Notably, a subgroup analysis showed that children receiving the standard daily dose of vitamin D experienced an even more significant improvement, with a risk ratio of 0.41.
Overall, we concluded that vitamin D3 supplementation holds the potential to lower asthma exacerbations in children. This is particularly encouraging as it also correlates with improved lung function, measured through FEV1. Hence, vitamin D3 could be a valuable addition to asthma management for young patients.
Our pooled analysis revealed promising results: vitamin D3 supplementation significantly reduced the overall number of asthma exacerbations. Specifically, we found a risk ratio of 0.62, indicating a notable decrease in attacks. Notably, a subgroup analysis showed that children receiving the standard daily dose of vitamin D experienced an even more significant improvement, with a risk ratio of 0.41.
Overall, we concluded that vitamin D3 supplementation holds the potential to lower asthma exacerbations in children. This is particularly encouraging as it also correlates with improved lung function, measured through FEV1. Hence, vitamin D3 could be a valuable addition to asthma management for young patients.
10
Resolved asthma flares
Most Useful Review
This supplement was a game changer for my daughter, who suffered from asthma flares. Her rheumatologist suggested "high dosing" as a possible solution for her fevers. I've purchased 13 bottles in two years, as my entire family uses it. I always keep two backups in case they stop making it or it goes out of stock.
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 9 Reviews
8.5
9.5
Essential health boost
Most Useful Review
I am extremely satisfied with the Vitamin D-3 supplement for both bone health and my immune system. It has become vital in my daily routine, notably helping with my bone pain and overall vitality. I highly recommend it for anyone wanting to increase their vitamin D intake.
Pelvic Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.4
9.5
Eliminated bone pain
Most Useful Review
The quality and packaging are excellent. It’s beneficial for health with safe ingredients and convenient dosage. My vitamin D levels improved significantly after taking it once a day during winter and autumn. My back and leg bone pain disappeared, and my immunity improved.
Blood Clot details
SCIENTIFIC SCORE
Questionable
Based on 9 Researches
6.1
USERS' SCORE
Medium or Average
Based on 3 Reviews
6.9
8
Vitamin D may influence blood clotting
Relationship between vitamin D deficiency and thrombus load in patients with ST-elevation myocardial infarction.
Most Relevant Research
We explored the connection between vitamin D levels and coronary thrombus load in patients who experienced ST-elevation myocardial infarction (STEMI). The study included 77 patients where we measured serum vitamin D levels, thrombus degree, and other relevant factors.
Our findings revealed that a concerning 79.22% of participants showed vitamin D deficiency, with those having milder thrombus loads possessing significantly higher vitamin D levels compared to those with severe thrombus loads. Moreover, as we assessed the severity of coronary artery condition, we noted that patients with higher thrombus burden also had markedly greater scores of atherosclerosis.
Importantly, we found clear negative correlations between vitamin D levels and measures of thrombus burden. Lower vitamin D levels aligned with higher TIMI frame counts—meaning more extensive vascular obstruction—suggesting that vitamin D might play a role in blood clot formation.
Overall, we determined that low 25(OH)D3 levels could be an independent predictor of high coronary artery thrombus load in STEMI patients. These findings highlight the potential significance of monitoring and perhaps addressing vitamin D levels in this vulnerable group.
Our findings revealed that a concerning 79.22% of participants showed vitamin D deficiency, with those having milder thrombus loads possessing significantly higher vitamin D levels compared to those with severe thrombus loads. Moreover, as we assessed the severity of coronary artery condition, we noted that patients with higher thrombus burden also had markedly greater scores of atherosclerosis.
Importantly, we found clear negative correlations between vitamin D levels and measures of thrombus burden. Lower vitamin D levels aligned with higher TIMI frame counts—meaning more extensive vascular obstruction—suggesting that vitamin D might play a role in blood clot formation.
Overall, we determined that low 25(OH)D3 levels could be an independent predictor of high coronary artery thrombus load in STEMI patients. These findings highlight the potential significance of monitoring and perhaps addressing vitamin D levels in this vulnerable group.
2.3
No effect observed
Most Useful Review
This vitamin D supplement did not work for my teenage son or me after several months. Despite beginning with a very low level of 20, our levels did not improve at all. I later switched to a different manufacturer, which resulted in improved vitamin D indicators.
