' 
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Calcium
115 mg
9%
Vitamin K2 (as menaquinone-7)
100 mcg
**
The product is found useful for the following medical conditions
Osteoporosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
USERS' SCORE
Good
Based on 21 Reviews
8.8
9
Vitamin K2 improves bone health
Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
Most Relevant Research
Our exploration focused on how vitamin K2 supplementation may aid postmenopausal women dealing with osteoporosis, particularly regarding bone mineral density (BMD) and the incidence of fractures over the long term. We meticulously reviewed nine randomized controlled trials with nearly 6,900 participants to gather insightful data on this topic.
The results were promising, revealing that vitamin K2 significantly enhanced lumbar and forearm BMD. Specifically, we observed notable increases in bone density measurements, alongside a reduction in undercarboxylated osteocalcin—a marker associated with bone health, and a significant rise in total osteocalcin.
Although there was an increase in the rate of adverse reactions in the vitamin K2 group, we found no serious side effects stemming from the supplementation. Overall, our study supports the conclusion that vitamin K2 is not only effective but also safe for treating osteoporosis in postmenopausal women. This could provide a welcome option for those looking to improve their bone health.
The results were promising, revealing that vitamin K2 significantly enhanced lumbar and forearm BMD. Specifically, we observed notable increases in bone density measurements, alongside a reduction in undercarboxylated osteocalcin—a marker associated with bone health, and a significant rise in total osteocalcin.
Although there was an increase in the rate of adverse reactions in the vitamin K2 group, we found no serious side effects stemming from the supplementation. Overall, our study supports the conclusion that vitamin K2 is not only effective but also safe for treating osteoporosis in postmenopausal women. This could provide a welcome option for those looking to improve their bone health.
9.5
Preventing osteoporosis
Most Useful Review
MK-7 is a highly bioavailable form of vitamin K2 involved in blood clotting and cellular regulation. It slows down the effects of natural aging and is vital for activating calcium-binding proteins. Vitamin K2 prevents osteoporosis and improves bone health. It is often taken alongside vitamin D, which aids calcium absorption, ensuring both vitamins work effectively. If my review is helpful, please click "Yes".
Cancer details
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
Vitamin K2 inhibits cancer cell growth
Vitamin K2 Inhibits Hepatocellular Carcinoma Cell Proliferation by Binding to 17β-Hydroxysteroid Dehydrogenase 4.
Most Relevant Research
We investigated how vitamin K2 (VK2) influences the growth of cancer cells, particularly focusing on hepatocellular carcinoma (HCC). Our study centered on the interaction between VK2 and a protein known as HSD17B4, which is known to promote cancer cell proliferation. Previous research had shown that VK2 can bind to this protein, but we aimed to uncover the specific mechanisms behind its potential anti-cancer effects.
Through our experiments, we observed that VK2 can inhibit the growth of HCC cells by binding directly to HSD17B4. Interestingly, VK2 did not alter the expression levels of HSD17B4, which suggests that its impact on cell growth is due to other mechanisms. Specifically, we found that VK2 impedes the activation of important signaling pathways, including AKT and MEK/ERK, which play a critical role in cancer cell proliferation. As a result, this inhibition leads to decreased activity of another protein, STAT3, associated with cancer growth.
Moreover, VK2 demonstrated the ability to suppress the growth of transplanted tumors that were influenced by HSD17B4. These findings not only shed light on VK2's mechanism of action, but they also offer promising insights into its potential role in preventing or treating HCC in future applications.
Through our experiments, we observed that VK2 can inhibit the growth of HCC cells by binding directly to HSD17B4. Interestingly, VK2 did not alter the expression levels of HSD17B4, which suggests that its impact on cell growth is due to other mechanisms. Specifically, we found that VK2 impedes the activation of important signaling pathways, including AKT and MEK/ERK, which play a critical role in cancer cell proliferation. As a result, this inhibition leads to decreased activity of another protein, STAT3, associated with cancer growth.
Moreover, VK2 demonstrated the ability to suppress the growth of transplanted tumors that were influenced by HSD17B4. These findings not only shed light on VK2's mechanism of action, but they also offer promising insights into its potential role in preventing or treating HCC in future applications.
8.8
Night sweats relief
Most Useful Review
A great solution for toothache and night sweats. I used Solgar K2 for a few weeks, and it stopped my night sweats and alleviated toothache. I feared I required a root canal, but the K2 eliminated the swelling and pain. Now I sleep comfortably without night sweats, and I no longer wake up agonised by pain. This has truly changed my life.
