Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Selenium (as L-selenomethionine)
200 mcg
364%
The product is found useful for the following medical conditions
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Significant improvement
Most Useful Review
1 people found this helpful
I took it to my mother (issues with the shield). She used it alongside tyrosine and colp. The outcome surpassed all expectations. The lump in my throat and mucus have vanished; I've begun to sleep soundly, and I've experienced a boost in energy.
Updated: Apr 2025
Cold Sores details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.6
10
No more colds!
Most Useful Review
Since I began taking Selenium alongside zinc, I have not experienced any further colds!
Updated: Apr 2025
Nausea details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 2 Reviews
8.6
7
This randomized, double-blind, crossover study explored how selenium impacts nausea and overall health in children and adolescents undergoing chemotherapy for leukemia, lymphomas, and solid tumors.
We noted a decrease in nausea and fatigue scores, particularly after a year of selenium supplementation in patients with solid tumors, suggesting it may alleviate some side effects of chemotherapy.
However, there were no significant changes for leukemia patients in nausea, despite improvements in fatigue and physical function. Overall, selenium supplementation shows promise in enhancing the quality of life for young cancer patients.
We noted a decrease in nausea and fatigue scores, particularly after a year of selenium supplementation in patients with solid tumors, suggesting it may alleviate some side effects of chemotherapy.
However, there were no significant changes for leukemia patients in nausea, despite improvements in fatigue and physical function. Overall, selenium supplementation shows promise in enhancing the quality of life for young cancer patients.
9
No nausea experienced
Most Useful Review
1 people found this helpful
Selenium is very comfortable for me—just dry selenium. This form does not cause discomfort, nausea, or other unwanted side effects. Excellent quality from Solgar. I take a dosage of 200mcg as prescribed by my doctor, followed by a break, and after 6-8 months, I switch to a maintenance dosage of 100mcg along with Vitamin E, also from Solgar. I have noticed positive results. It is a standard tablet, rather than a capsule, and can be divided easily.
Updated: Apr 2025
Prostate Cancer details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Good
Based on 4 Reviews
8.6
8
We explored the impact of selenium nanoparticles, known for their potential anti-cancer properties, on aggressive prostate cancer cells, specifically the PC-3 line. The study focused on understanding how sub-toxic levels of selenium functionalized nanoparticles affect cell proliferation and their intracellular behavior.
By utilizing advanced imaging techniques and careful cryopreparation, we aimed to preserve the integrity of the cancer cells while analyzing the distribution of these nanoparticles within them. Our findings revealed that nanoparticles coated with bovine serum albumin (BSA) reduced the migration capability of the cancer cells more effectively than those coated with chitosan.
This difference may be attributed to the BSA coating's ability to prevent harmful interactions with the cell membranes, which in turn limits the generation of reactive oxygen species that can damage cells. Most intriguingly, we observed that these selenium nanoparticles localized in both the mitochondria and lysosome-related organelles within the cells. The presence of nanoparticles in the mitochondria might explain the significant reduction in the PC-3 cells' ability to proliferate.
Overall, our investigation highlights the promising role selenium nanoparticles can play in cancer treatment strategies, providing valuable insights for further research into their cytotoxic mechanisms against prostate cancer.
By utilizing advanced imaging techniques and careful cryopreparation, we aimed to preserve the integrity of the cancer cells while analyzing the distribution of these nanoparticles within them. Our findings revealed that nanoparticles coated with bovine serum albumin (BSA) reduced the migration capability of the cancer cells more effectively than those coated with chitosan.
This difference may be attributed to the BSA coating's ability to prevent harmful interactions with the cell membranes, which in turn limits the generation of reactive oxygen species that can damage cells. Most intriguingly, we observed that these selenium nanoparticles localized in both the mitochondria and lysosome-related organelles within the cells. The presence of nanoparticles in the mitochondria might explain the significant reduction in the PC-3 cells' ability to proliferate.
Overall, our investigation highlights the promising role selenium nanoparticles can play in cancer treatment strategies, providing valuable insights for further research into their cytotoxic mechanisms against prostate cancer.
9
Cancer prevention
Most Useful Review
1 people found this helpful
I take selenium as advised by a German doctor for cancer prevention. Previously, I used inorganic selenium but have now switched to a more affordable Solgar product. I split the pill in half since the recommended dose is 100 mcg, allowing this package to last over a year!
Updated: Apr 2025
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.6
9
Nodes decreased significantly
Most Useful Review
29 people found this helpful
Selenium is an element that helps to maintain the normal functioning of the thyroid gland. After taking it, my TSH returned to normal, and the enlarged nodes decreased on the ultrasound while the smaller ones vanished! To support my thyroid gland, I take a course once a year for a month. I am very pleased with the results.
Updated: Apr 2025
Cardiovascular Disease details
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
This study focused on how selenium-loaded porous silica nanospheres (Se@PSN) could help repair the heart following a myocardial infarction (MI). These tiny particles are designed to neutralize harmful molecules called reactive oxygen species, which play a significant role in heart damage during MI.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
9
Reduces thyroid antibodies
Most Useful Review
1 people found this helpful
I have been using this form of selenium for autoimmune thyroid disease for three years now, and it has significantly reduced my thyroid antibodies while improving my overall well-being. Truly excellent!
Updated: Mar 2026
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
7.5
Enhanced well-being
Most Useful Review
The product is of excellent quality, both in formulation and packaging. The brand pays attention to detail, evident in each product. The tablets are standard-sized and easy to swallow. Selenium is a powerful antioxidant, essential for maintaining immunity and protecting cells from oxidative stress. After a few weeks, I noticed improvements in my overall well-being, reduced fatigue, and enhanced skin quality. This is a great way to boost selenium levels, especially for those who lack it in their diet, particularly during winter.
Updated: Mar 2026
Hyperthyroidism details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Boosted immunity
Most Useful Review
This product helped with hyperthyroidism perfectly, boosting my immunity. Since using it, my hair has stopped falling out. I took it alongside D3, magnesium citrate, and calcium, all from Solgar, with great effect!
Updated: Apr 2025
Hypothyroidism details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.6
USERS' SCORE
Good
Based on 8 Reviews
8.5
8
We explored the effects of selenium supplementation in patients suffering from Hashimoto thyroiditis (HT), a leading cause of hypothyroidism. By analyzing multiple randomized controlled trials, we aimed to see how selenium might impact thyroid function, particularly focusing on thyroid-stimulating hormone (TSH) levels and thyroid antibodies.
Our analysis included results from 35 studies, where we observed that selenium supplementation led to a notable decrease in TSH levels among patients not undergoing thyroid hormone replacement therapy. This suggests that selenium may help manage thyroid function in specific populations.
Additionally, we found that selenium also reduced levels of thyroid peroxidase antibodies (TPOAb) and malondialdehyde (MDA), which indicates improved thyroid health and reduced oxidative stress. Interestingly, we observed that these benefits occurred irrespective of whether patients were receiving thyroid hormone therapy.
However, we did not find significant changes in other thyroid hormones or immune markers, indicating that while selenium can be effective in some areas, its benefits may not extend across all measures of thyroid health. Overall, our findings support the safe use of selenium in lowering TSH and certain antibodies in HT patients not on hormone therapy.
Our analysis included results from 35 studies, where we observed that selenium supplementation led to a notable decrease in TSH levels among patients not undergoing thyroid hormone replacement therapy. This suggests that selenium may help manage thyroid function in specific populations.
Additionally, we found that selenium also reduced levels of thyroid peroxidase antibodies (TPOAb) and malondialdehyde (MDA), which indicates improved thyroid health and reduced oxidative stress. Interestingly, we observed that these benefits occurred irrespective of whether patients were receiving thyroid hormone therapy.
However, we did not find significant changes in other thyroid hormones or immune markers, indicating that while selenium can be effective in some areas, its benefits may not extend across all measures of thyroid health. Overall, our findings support the safe use of selenium in lowering TSH and certain antibodies in HT patients not on hormone therapy.
10
Reversed hypothyroidism
Most Useful Review
7 people found this helpful
This product has reversed my hypothyroidism, combined with Vitamin C and zinc.
Updated: Apr 2025
Low Libido details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.4
9
Increased libido
Most Useful Review
2 people found this helpful
Great selenium! I spent a month with my husband. A test for selenium deficiency was conducted before starting the treatment, and the results were promising. After a month, we observed noticeable effects; my husband's libido significantly increased, which is vital for men. Maintaining a healthy selenium level is crucial.
Updated: Apr 2025
Autoimmune Disorder details
SCIENTIFIC SCORE
Questionable
Based on 17 Researches
6.9
USERS' SCORE
Good
Based on 7 Reviews
8.3
9
Selenium aids Graves' orbitopathy treatment
We explored how selenium supplementation might help individuals suffering from Graves' orbitopathy, an autoimmune disorder linked to thyroid dysfunction. Our approach involved a systematic review and meta-analysis that assessed results from four randomized controlled trials.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.
We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.
Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
9
Decreased antibodies
Most Useful Review
14 people found this helpful
Good analyses! After the course of selenium, my antibodies decreased with autoimmune thyroiditis!
Updated: Apr 2025
Cancer details
SCIENTIFIC SCORE
Moderately Effective
Based on 27 Researches
8.3
USERS' SCORE
Good
Based on 4 Reviews
8.3
9.5
We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival.
The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells.
Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients.
The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells.
Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients.
9
Reduces cancer risk
Most Useful Review
9 people found this helpful
Reduced cancer risk. This is an excellent mineral to take. It helps the liver combat toxins and lowers cancer risk by 50%. I love it!
Updated: Apr 2025
Sleep Apnea details
SCIENTIFIC SCORE
Questionable
Based on 1 Research
5
USERS' SCORE
Good
Based on 6 Reviews
8.3
5
We examined the levels of selenium and key vitamins in patients suffering from obstructive sleep apnea (OSA) without additional health issues. Our study, involving 146 subjects split into different OSA severity levels, aimed to understand how these antioxidants might play a role in OSA's impact on health.
Interestingly, we found that higher concentrations of selenium and vitamin A appeared to bolster the body’s defense against OSA. Although our findings suggest potential benefits, it's important to note that antioxidants alone should not replace conventional treatments for OSA.
Interestingly, we found that higher concentrations of selenium and vitamin A appeared to bolster the body’s defense against OSA. Although our findings suggest potential benefits, it's important to note that antioxidants alone should not replace conventional treatments for OSA.
9
Improved overall wellbeing
Most Useful Review
Taking this supplement has been excellent for me so far. I've gained more energy and am sleeping better than ever. I believe this supplement helps to enhance my overall health.
Updated: Mar 2026
Hashimoto details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 6 Reviews
8.2
9
We examined the impact of selenium supplements on thyroid autoantibody levels in patients with Hashimoto's thyroiditis.
In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.
However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.
This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.
In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.
However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.
This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.
7.5
Effective for antibodies
Most Useful Review
2 people found this helpful
I have been using this product successfully as part of a strategy to reduce Anti-TPO antibodies and manage Hashimoto's thyroiditis. However, one must be cautious with dosages and administration times, as too much selenium can be harmful.
Updated: Apr 2025
Hypertension details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.2
7.5
Necessary for recovery
Most Useful Review
Excellent! Crucial for arrhythmia, ischaemic heart disease, hypertension, atherosclerosis, and during recovery after a myocardial infarction. Selenium normalises fat metabolism and cholesterol levels in the blood, protects blood vessels and heart muscle from damage, and reduces the chances of developing hypertension.
Updated: Apr 2025
Acne details
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 2 Reviews
8.1
8
We examined how selenium supplementation impacts acne among women with polycystic ovary syndrome (PCOS) through a rigorous 8-week trial. In a randomized double-blind and placebo-controlled setup, we compared 32 women taking 200 μg of selenium daily against 32 taking a placebo.
Notably, those receiving selenium showed a significant drop in acne rates, from 12.5% in the placebo group to 46.9% in the selenium group. This indicates that selenium might indeed help reduce acne, alongside other reproductive and health improvements. However, some hormonal factors didn't show notable changes.
Notably, those receiving selenium showed a significant drop in acne rates, from 12.5% in the placebo group to 46.9% in the selenium group. This indicates that selenium might indeed help reduce acne, alongside other reproductive and health improvements. However, some hormonal factors didn't show notable changes.
7
Effective acne treatment
Most Useful Review
1 people found this helpful
The quality is good, the ingredients are beneficial, and the packaging is very useful. I purchased it for my son to help with his acne, and I find it to be an important supplement. The flavour has no aftertaste, and there are no side effects.
Updated: Oct 2025
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.1
6
Immunity boost
Most Useful Review
In today's world of viruses, zinc, vitamin D3, vitamin C, and selenium are essential to prevent COVID-19. Selenium strengthens immunity, protects the lungs, and supports the thyroid when combined with iodine. It improves conditions of the skin and hair, alleviates chronic fatigue syndrome, and helps fight atherosclerosis. The tablets are small, and their specific smell won't hinder your health improvement.
Updated: Apr 2025
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
USERS' SCORE
Good
Based on 8 Reviews
8.1
9
Selenium nanoparticles support heart health
We explored how selenium nanoparticles (SeNPs) could help reduce damage from heart attacks, specifically ischemia/reperfusion injury (I/RI). Using a method to create these nanoparticles, we found they possess remarkable properties that combat oxidative stress and inflammation.
SeNPs seem to disrupt harmful cellular cycles, thereby protecting heart cells. Notably, they improved heart function and reduced cell death and scar tissue in tests. Overall, these findings suggest that SeNPs could be a valuable approach in managing heart conditions after a heart attack.
SeNPs seem to disrupt harmful cellular cycles, thereby protecting heart cells. Notably, they improved heart function and reduced cell death and scar tissue in tests. Overall, these findings suggest that SeNPs could be a valuable approach in managing heart conditions after a heart attack.
9
Supports heart health
Most Useful Review
2 people found this helpful
This product is excellent; I’ve been taking it for a long time with other supplements to boost my immune system. Recently, I’ve increased my dosage due to my hypothyroidism. I discovered that selenium is concentrated in the thyroid as it is essential for metabolic processes. Various studies have shown that selenium supplementation improves thyroid structure and can lead to quicker remission in certain diseases.
Updated: Apr 2025
Pelvic Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.4
7
We sought to understand how a mineral-vitamin complex, specifically Selzinc-plus, may help treat chronic abacterial prostatitis, a condition often linked with pelvic pain. In a study involving 47 men, we divided them into two groups: one received standard therapy, and the other received additional Selzinc-plus for two months.
While standard therapy showed effects, the antioxidant treatment significantly enhanced these benefits on symptoms. Notably, though the overall antioxidant system improved, no significant changes were observed in leukocyte counts. Our findings suggest that this antioxidant approach may offer added relief for those suffering from pelvic pain.
While standard therapy showed effects, the antioxidant treatment significantly enhanced these benefits on symptoms. Notably, though the overall antioxidant system improved, no significant changes were observed in leukocyte counts. Our findings suggest that this antioxidant approach may offer added relief for those suffering from pelvic pain.
2
Hair loss concern
Most Useful Review
I purchased this product after reading rave reviews regarding its effects on hair. Unfortunately, upon commencing intake, I began to experience pain under my left rib. I became cautious, considering I was also on other supplements, but it seemed the discomfort arose after consuming selenium. My hair also started to thin. To confirm, I ordered a laboratory test that revealed a selenium overdose in my body, despite taking only one pill daily for a couple of weeks. Once I discontinued it, the pain subsided. It's important to get tested before starting any new supplements.
Updated: Apr 2025
Hair Loss details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Medium or Average
Based on 6 Reviews
6.1
8
Selenium aids hair loss in PCOS
We conducted a randomized double-blind, placebo-controlled trial to explore how selenium supplementation may influence hair loss among women with polycystic ovary syndrome (PCOS). In the study, 64 women aged 18-40 received either 200 μg of selenium daily or a placebo for eight weeks.
After the treatment period, we noticed a significant improvement in hair-related issues for those taking selenium. Specifically, alopecia rates dropped from 40.6% in the selenium group to just 9.4% in the placebo group, showing a strong positive effect of the supplement on hair loss. Acne also improved, with a reduction from 46.9% to 12.5%.
Furthermore, women who took selenium supplements exhibited decreased levels of dehydroepiandrosterone (DHEA), hirsutism, and markers of inflammation and oxidative stress. However, it’s important to note that selenium did not show significant effects on some hormonal profiles and other biomarkers. Overall, our findings suggest that selenium can be beneficial for women with PCOS, particularly regarding hair loss and related symptoms.
After the treatment period, we noticed a significant improvement in hair-related issues for those taking selenium. Specifically, alopecia rates dropped from 40.6% in the selenium group to just 9.4% in the placebo group, showing a strong positive effect of the supplement on hair loss. Acne also improved, with a reduction from 46.9% to 12.5%.
Furthermore, women who took selenium supplements exhibited decreased levels of dehydroepiandrosterone (DHEA), hirsutism, and markers of inflammation and oxidative stress. However, it’s important to note that selenium did not show significant effects on some hormonal profiles and other biomarkers. Overall, our findings suggest that selenium can be beneficial for women with PCOS, particularly regarding hair loss and related symptoms.
9
Reduced hair loss
Most Useful Review
2 people found this helpful
Excellent product. Very high quality. It has made a significant difference in reducing hair loss and normalising thyroid hormones. Definitely recommend!
Updated: Apr 2025
Data last updated:
