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Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Wild Caught Fish Oil Concentrate
1250 mg
†
Total Omega-3 Fatty Acids as TG
1055 mg
†
EPA (Eicosapentaenoic Acid)
690 mg
†
DHA (Docosahexaenoic Acid)
310 mg
†
Other Omega-3 Fatty Acids
55 mg
†
The product is found useful for the following medical conditions
Reflux details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 13 Reviews
8.8
10
No reflux
Most Useful Review
Easy to take! I had given up on fish oil as every brand gave me reflux. My sister-in-law recommended these, and they're amazing! There’s no fishy taste, no reflux, and no burping. They are also surprisingly easy to swallow given their size.
Anxiety details
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.4
USERS' SCORE
Good
Based on 3 Reviews
8.6
8
DHA improves milk and reduces anxiety
DHA Supplementation of Obese Rats throughout Pregnancy and Lactation Modifies Milk Composition and Anxiety Behavior of Offspring.
Most Relevant Research
We explored how supplementing obese mothers with docosahexaenoic acid (DHA) affects milk composition and the anxiety behavior of their offspring. In a study involving female Wistar rats, some were placed on a high-fat diet while others ate regular chow. We supplemented half of the mothers from one month before mating until they weaned their pups with DHA. The goal was to see if this supplementation could improve the quality of their milk and influence the anxiety levels of their babies.
Our findings indicated that the obese mother rats exhibited higher weight and fat levels and their milk contained less beneficial DHA but more corticosterone and leptin. Notably, their offspring showed a higher ratio of omega-6 to omega-3 fatty acids in the milk they consumed, which correlates to increased anxiety levels, especially in female pups. In contrast, those mothers who received DHA supplements had lower body weight and fat and produced milk with higher DHA content. Their offspring not only had a better balance of omega-6 to omega-3 fatty acids but also demonstrated reduced anxiety compared to those from mothers without supplementation.
Overall, this study highlights the significant positive impact of DHA supplementation during pregnancy and lactation in obese rats, as it not only improves the nutritional quality of their milk but also helps decrease anxiety levels in the offspring in a sex-dependent manner.
Our findings indicated that the obese mother rats exhibited higher weight and fat levels and their milk contained less beneficial DHA but more corticosterone and leptin. Notably, their offspring showed a higher ratio of omega-6 to omega-3 fatty acids in the milk they consumed, which correlates to increased anxiety levels, especially in female pups. In contrast, those mothers who received DHA supplements had lower body weight and fat and produced milk with higher DHA content. Their offspring not only had a better balance of omega-6 to omega-3 fatty acids but also demonstrated reduced anxiety compared to those from mothers without supplementation.
Overall, this study highlights the significant positive impact of DHA supplementation during pregnancy and lactation in obese rats, as it not only improves the nutritional quality of their milk but also helps decrease anxiety levels in the offspring in a sex-dependent manner.
9.5
Anxiety diminished
Most Useful Review
It just works! I've tried every fish oil on the market but never found any benefits. After trying Sports Research fish oil, I noticed immediate relief from my knee pain and a remarkable improvement in my anxiety. My anxiety has lessened considerably since taking it, and I will never switch back to other brands.
Back Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Eicosapentaenoic acid alleviates back pain
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Most Relevant Research
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
9.5
Reduced inflammation
Most Useful Review
I have suffered from severe rheumatoid arthritis for over 40 years, with pain levels often between 6 and 10. My son suggested trying Sports Research brand omega-3 fish oil, which I commenced taking twice daily. Within a month, I noticed a considerable reduction in inflammation throughout my body, including my painfully swollen ankles. Thanks to this product, I hope to avoid returning to uncomfortable footwear meant to reduce swelling.
Cataract details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Cholesterol improvement noted
Most Useful Review
EDIT: My cholesterol dropped significantly over the last year, which has made me very happy. I attributed this change to taking an omega supplement with astaxanthin consistently. This is the only notable change I have made, and my doctor was impressed with the results. I have taken Nordic Naturals for years, but now I find that this new product is equally effective and more cost-efficient.
Hot Flashes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Almost complete cessation
Most Useful Review
It stops hot flashes 98%! I take this for severe hot flashes, and it almost eliminates them. One a day keeps the hot flashes away.
Indigestion details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Happy with results
Most Useful Review
Works well and doesn’t have a fishy taste. Initially, I was reluctant to take fish oil due to prior unpleasant experiences with indigestion and the taste. I decided to choose this well-reviewed supplement and couldn’t be more pleased.
Rheumatoid Arthritis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Significant inflammation reduction
Most Useful Review
I love this product! I have suffered from severe rheumatoid arthritis for over 40 years. My pain levels are often horrific while on medication. My son suggested I try Sports Research brand fish oil. Within a month, I noticed a tremendous reduction in inflammation throughout my body. It is working alongside my other medications. I hope to avoid the awful compression socks and shoes that used to alleviate my swelling.
Acne details
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.2
USERS' SCORE
Good
Based on 1 Review
8.5
We observed that acne is a common skin condition, particularly affecting individuals under 30. Our exploration into the role of diet revealed that nutrition significantly influences acne development. Among the various dietary components, omega-3 fatty acids stood out due to their potential anti-inflammatory properties.
The research indicates that foods rich in omega-3 can help reduce the production of inflammatory substances that may contribute to acne. Additionally, specific fatty acids, such as docosapentaenoic acid and γ-linolenic acid, have shown promise in improving acne lesions.
By integrating omega-3 into the diet, we might be able to mitigate some of the troublesome symptoms associated with acne. While the evidence is still unfolding, the link between omega-3 fatty acids and reduced acne severity offers a hopeful avenue worth considering for those battling breakouts.
The research indicates that foods rich in omega-3 can help reduce the production of inflammatory substances that may contribute to acne. Additionally, specific fatty acids, such as docosapentaenoic acid and γ-linolenic acid, have shown promise in improving acne lesions.
By integrating omega-3 into the diet, we might be able to mitigate some of the troublesome symptoms associated with acne. While the evidence is still unfolding, the link between omega-3 fatty acids and reduced acne severity offers a hopeful avenue worth considering for those battling breakouts.
8.8
Quality Omega-3 effect
Most Useful Review
The best Omega-3 option! Each capsule contains 1250 mg of fish oil. I've noticed a decrease in the number of acne and an overall improvement in skin quality. It's worth investing in quality Omega-3 for better absorption.
Bloating details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 19 Reviews
8.5
9.5
Weight loss achieved
Most Useful Review
I lost weight, but that isn’t my main reason for taking it. I've struggled with obesity for over 50 years and have faced constant bloating, pressure, and discomfort in my stomach area for the last five years. After extensive research on how to alleviate the bloating and pain, I came across Omega-3 fatty acids. Though I consume 2500mg daily mixed into a protein shake, in just three months, I've lost 18 pounds. I no longer have bloating or pressure in my stomach, and my blood pressure has improved significantly.
Brain Tumor details
SCIENTIFIC SCORE
Moderately Effective
Based on 13 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
DHA liposomes show promise
Microfluidic-derived docosahexaenoic acid liposomes for glioblastoma therapy.
Most Relevant Research
We explored an innovative approach to treating glioblastoma, the most common malignant brain tumor, by utilizing docosahexaenoic acid (DHA) liposomes. These liposomes were created using a microfluidic system that allowed for fine-tuning various properties, which could enhance their effectiveness in targeting tumor cells.
Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.
Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.
Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
8.8
Stimulates brain development
Most Useful Review
I find that omega-3s from cold water fish provide the best absorption. This supplement restores neurons, positively impacting brain function and development. While it can cause hyperactivity, the effects are generally very beneficial.
Hypertension details
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.6
USERS' SCORE
Good
Based on 1 Review
8.5
9
Eicosapentaenoic acid benefits hypertension
5,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP signaling pathway.
Most Relevant Research
We investigated the impact of eicosapentaenoic acid (EPA) on hypertension, a condition characterized by elevated blood pressure that can lead to serious health issues. The study focused on a special compound called 5,6-diHETE lactone (EPA-L), derived from EPA, which we observed to promote better blood vessel function. This compound was tested on hypertensive rats and showed a significant reduction in blood pressure.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health.
8.8
Weight loss achieved
Most Useful Review
I lost weight though that’s not why I’m taking it. I've struggled with obesity for over 50 years and have constant bloating and discomfort. Despite not being able to lose weight previously, I researched how to alleviate my bloating and raise low "good" cholesterol. After including fish oil daily, I've lost 18 pounds in three months, and my blood pressure has also decreased from borderline stage 1 hypertension. The only change has been adding this product daily, and I am thrilled about the results.
Neuropathy details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8
Quality of life improvement
Most Useful Review
I've used this product for pain relief related to diabetic neuropathy and other conditions. After three months, I struggled to notice improvements. However, when I ran out, my symptoms flared up, and upon returning, I noticed a significant enhancement in my quality of life.
Arthritis details
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.3
USERS' SCORE
Good
Based on 25 Reviews
8.4
8
Eicosapentaenoic acid aids arthritis
Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials.
Most Relevant Research
We explored the effects of eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, on patients with rheumatoid arthritis (RA). This analysis gathered data from eighteen randomized controlled trials involving over a thousand RA patients, ensuring a comprehensive look at its impact.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement.
8.8
Pain relief
Most Useful Review
Despite the high price, I find this omega-3 to be the best available in terms of quality and ingredients. It effectively alleviates my arthritis pain when combined with vitamin D and curcumin, and even enhances my focus, which I had been losing due to my condition.
Common Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 20 Reviews
8.4
8
DHA reduces infant cold symptoms
Prenatal docosahexaenoic acid supplementation and infant morbidity: randomized controlled trial.
Most Relevant Research
We conducted a double-blind randomized controlled trial to understand how prenatal supplementation of docosahexaenoic acid (DHA) might influence infant health, particularly concerning the common cold. Pregnant women were given either a daily dose of 400 mg of DHA or a placebo starting at 18 to 22 weeks of gestation until childbirth.
Caregivers then reported on their infants’ health at 1, 3, and 6 months, sharing details about common illness symptoms. We found that DHA supplementation appeared to reduce the number of colds at one month and also seemed to lessen the duration of various cold symptoms in infants. Specifically, infants in the DHA group experienced fewer cold symptoms and had shorter durations of cough and wheezing.
While the overall occurrence of specific illness symptoms was similar between the DHA and placebo groups, DHA did bring about noteworthy benefits. At 1 month, infants in the DHA group had a 26% shorter duration of cough and 30% shorter wheezing; however, they experienced a longer duration of rash.
Furthermore, by the time the infants reached 3 months, those whose mothers took DHA were ill for 14% less time overall. At 6 months, the DHA group showed significantly reduced durations of several illness indicators, although they did experience longer episodes of vomiting.
This study suggests that prenatal DHA not only seems to impact the occurrence of colds in children but may also play a role in the duration of symptoms over the first half-year of life.
Caregivers then reported on their infants’ health at 1, 3, and 6 months, sharing details about common illness symptoms. We found that DHA supplementation appeared to reduce the number of colds at one month and also seemed to lessen the duration of various cold symptoms in infants. Specifically, infants in the DHA group experienced fewer cold symptoms and had shorter durations of cough and wheezing.
While the overall occurrence of specific illness symptoms was similar between the DHA and placebo groups, DHA did bring about noteworthy benefits. At 1 month, infants in the DHA group had a 26% shorter duration of cough and 30% shorter wheezing; however, they experienced a longer duration of rash.
Furthermore, by the time the infants reached 3 months, those whose mothers took DHA were ill for 14% less time overall. At 6 months, the DHA group showed significantly reduced durations of several illness indicators, although they did experience longer episodes of vomiting.
This study suggests that prenatal DHA not only seems to impact the occurrence of colds in children but may also play a role in the duration of symptoms over the first half-year of life.
9.5
Strengthened immunity
Most Useful Review
Great Omega 3! I bought this Omega 3 specifically for my husband. The dosage is excellent in one capsule, lasting two months. He takes one capsule daily, alongside vitamin D3 with meals. He appreciates the ease of use and its effectiveness. Before taking Omega 3, he frequently caught a common cold and suffered from weakness. Since its regular intake began, he hasn't been ill all autumn nor now! He has noticed an increase in strength and energy! An excellent result! We will reorder.
Heartburn details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 16 Reviews
8.3
9.5
No heartburn experienced
Most Useful Review
Great product. I only need one pill instead of three, with no aftertaste, burping, or heartburn. These are fantastic!
Allergies details
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.9
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.3
8
Omega-3s and skin allergies
ω3 fatty acid metabolite, 12-hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor α.
Most Relevant Research
We uncovered intriguing insights into how eicosapentaenoic acid (EPA) and its metabolite, 12-hydroxyeicosapentaenoic acid (12-HEPE), play a role in managing allergic responses, particularly in the skin. Our study revealed that when mice consumed an omega-3 fatty acid-rich diet, 12-HEPE became a significant metabolite in their skin.
Interestingly, we observed that the enzymes responsible for producing 12-HEPE were more active in the skin compared to other organs. This effective metabolite appeared to reduce inflammation caused by contact hypersensitivity. Specifically, we found that applying 12-HEPE topically limited the influx of neutrophils, a type of white blood cell involved in inflammatory responses.
Taking our research a step further, we investigated the effects of 12-HEPE on human skin cells, or keratinocytes, in lab conditions. Our findings showed that 12-HEPE inhibited two specific genes that cause neutrophils to be attracted to the site of inflammation, showcasing its potential as a therapeutic agent for allergy management. Overall, we identified 12-HEPE as a potent metabolite in the skin, suggesting that dietary omega-3 fatty acids could be a beneficial strategy in controlling allergic reactions.
Interestingly, we observed that the enzymes responsible for producing 12-HEPE were more active in the skin compared to other organs. This effective metabolite appeared to reduce inflammation caused by contact hypersensitivity. Specifically, we found that applying 12-HEPE topically limited the influx of neutrophils, a type of white blood cell involved in inflammatory responses.
Taking our research a step further, we investigated the effects of 12-HEPE on human skin cells, or keratinocytes, in lab conditions. Our findings showed that 12-HEPE inhibited two specific genes that cause neutrophils to be attracted to the site of inflammation, showcasing its potential as a therapeutic agent for allergy management. Overall, we identified 12-HEPE as a potent metabolite in the skin, suggesting that dietary omega-3 fatty acids could be a beneficial strategy in controlling allergic reactions.
7
Resolved allergies
Most Useful Review
I bought this on my doctor's recommendation. After taking it for three months, my body returned to normal and I had no allergies. I gave it three stars to keep the price down, but the brand is excellent!
