Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Wild Caught Fish Oil Concentrate
1250 mg
â€
Total Omega-3 Fatty Acids as TG
1055 mg
â€
EPA (Eicosapentaenoic Acid)
690 mg
â€
DHA (Docosahexaenoic Acid)
310 mg
â€
Other Omega-3 Fatty Acids
55 mg
â€
The product is found useful for the following medical conditions
High Cholesterol details
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.7
USERS' SCORE
Good
Based on 63 Reviews
8.7
9
Eicosapentaenoic acid benefits cholesterol
We explored the effects of eicosapentaenoic acid (EPA), a specific type of omega-3 fatty acid, on cholesterol levels in a recent study involving real-world supplement consumers. Participants took AlmegaPL capsules, which contain high amounts of EPA and are free of the other omega-3 fatty acid, DHA. This setup allowed us to gain insights from those who are already incorporating EPA into their diets.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
9
Decreased cholesterol levels
Most Useful Review
270 people found this helpful
I take this Omega-3 regularly! It’s very convenient that it contains all necessary fats in one capsule, which lasts a long time. I find 1 capsule daily sufficient. The large capsules are easy to swallow and have no smell. I haven’t experienced any side effects; rather, I feel much better, my nails no longer peel, my skin has cleared up, and my hair loss has reduced. Notably, my cholesterol levels have decreased. This Omega obviously works well for me, and I really appreciate it.
Updated: Mar 2026
Reflux details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8.7
10
No reflux
Most Useful Review
8 people found this helpful
Easy to take! I had given up on fish oil as every brand gave me reflux. My sister-in-law recommended these, and they're amazing! There’s no fishy taste, no reflux, and no burping. They are also surprisingly easy to swallow given their size.
Updated: Mar 2026
Constipation details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.6
10
Helps constipation
Most Useful Review
16 people found this helpful
Hello Omega good helps with constipation, very satisfied. 😀
Updated: Apr 2025
Floaters details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.6
10
Significant improvement
Most Useful Review
Very good Weight: A large piece of fish oil that I usually swallow with my meals, like breakfast. Taste: Occasionally, I bite it to absorb the oil, which leads to a fishy flavour. Packaging: Texture. Benefits: Assists the eyes. My wife noted that my eyes had been prone to soreness and floaters. After consistently consuming this product over the past few days, I have seen significant improvement. Now, I experience nearly no floaters, so the quality is excellent.
Updated: Apr 2025
Alzheimer details
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.1
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
We investigated the potential benefits of docosahexaenoic acid (DHA) in fighting Alzheimer's disease (AD) through a novel intranasal administration method. By using a specially formulated nanoemulsion that protects DHA from oxidation, we aimed to enhance its delivery to the brain. In our study, we administered this DHA-rich nanoemulsion to J20 mice, a well-known transgenic model for AD.
The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.
Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients.
The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.
Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients.
9
Comprehensive health benefits
Most Useful Review
This Omega-3 fish oil soft gel is derived from high-quality deep-sea fish, ensuring purity and efficacy. It provides significant health benefits: it lowers cholesterol and triglyceride levels, promotes brain development, improves mood, and helps prevent Alzheimer’s. It effectively relieves joint inflammation and pain, making it a convenient and beneficial supplement with excellent quality and easy-to-take soft gel design.
Updated: Mar 2026
Athlete’s Foot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Warmer extremities
Most Useful Review
1 people found this helpful
I take one tablet after lunch and another after dinner. I was concerned about my high triglyceride levels from health check-ups, but I was astonished to see improvements after starting the Omega-3 supplement. Additionally, perhaps because it thins my blood, my sensitivity to cold has increased, and my hands and feet feel much warmer.
Updated: Apr 2025
Eczema details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.4
USERS' SCORE
Good
Based on 7 Reviews
8.5
9
We embarked on a study to find out how dietary eicosapentaenoic acid (EPA) could help children suffering from atopic dermatitis, a common form of eczema. In a randomized triple-blind clinical trial, 48 children with this condition were divided into two groups—one received 250 mg of EPA twice daily, while the other received a placebo for four weeks.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
Our observations showed noticeable improvements in those who took EPA. After just two weeks, participants in the EPA group reported a reduction in their SCORAD scores, which are used to measure the severity of atopic dermatitis. The scores went down significantly compared to the placebo group. After four weeks, the number of children needing corticosteroids to manage their symptoms was also lower in the EPA group.
Despite these positive results, both groups reported few adverse effects, indicating that EPA supplementation is generally well-received. Overall, we conclude that adding EPA to the diet may be an effective and safe strategy for reducing eczema severity in children.
9
Eczema relief experienced
Most Useful Review
1 people found this helpful
This product helps with eczema.
Updated: Mar 2026
Influenza details
SCIENTIFIC SCORE
Questionable
Based on 9 Researches
6.8
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
We explored the potential of docosahexaenoic acid (DHA) and its derived compound, protectin DX (PDX), specifically in the context of influenza virus replication. The research highlights how poxytrins, which are dihydroxy derivatives formed from PUFA, may play a significant role in addressing inflammation and viral issues due to their unique structure.
Protectin DX is known for its ability to inhibit the activities of cyclooxygenase (COX), which are linked to inflammatory processes, as well as reducing the formation of harmful reactive oxygen species (ROS). Interestingly, we observed that PDX also has the potential to limit the replication of influenza viruses by interfering with their RNA metabolism.
While the study emphasizes this unique dual action, it should be noted that it primarily focuses on the effect of PDX alone, without comprehensive exploration of combined effects with other treatments. Regardless, the findings suggest a promising pathway for using DHA-derived compounds in viral mitigation, particularly relating to influenza.
Protectin DX is known for its ability to inhibit the activities of cyclooxygenase (COX), which are linked to inflammatory processes, as well as reducing the formation of harmful reactive oxygen species (ROS). Interestingly, we observed that PDX also has the potential to limit the replication of influenza viruses by interfering with their RNA metabolism.
While the study emphasizes this unique dual action, it should be noted that it primarily focuses on the effect of PDX alone, without comprehensive exploration of combined effects with other treatments. Regardless, the findings suggest a promising pathway for using DHA-derived compounds in viral mitigation, particularly relating to influenza.
9
Influenza support benefits
Most Useful Review
Fish oil offers significant benefits due to its Omega-3 fatty acids, EPA and DHA. These nutrients maintain heart health, support vision, combat inflammation and infection, and promote brain health. Notably, Omega-3s have been shown to inhibit influenza viruses while also helping to alleviate rheumatoid arthritis pain. The high-quality ingredients and lack of unusual taste make it an essential nutritional supplement for overall well-being and fitness.
Updated: Apr 2025
Migraine details
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
USERS' SCORE
Good
Based on 7 Reviews
8.5
9.5
We conducted a thorough investigation into how eicosapentaenoic acid (EPA) can impact episodic migraines. In a carefully designed study, we gathered 70 participants who experienced these migraines and divided them into two groups. One group received a high dose of EPA, while the other was given a placebo. This approach ensured that we could see the true effects of EPA without bias.
After 12 weeks, the results were compelling. We noticed that those taking EPA had significantly fewer migraine days compared to the placebo group. In fact, participants on EPA reported an average reduction of 4.4 days per month, while those on the placebo had barely any change. The EPA group also experienced less need for acute headache medication and marked improvements in headache severity, disability, anxiety, depression, and overall quality of life.
Perhaps most striking was how particularly beneficial EPA seemed to be for female participants. Overall, the study demonstrated that high-dose EPA not only helped reduce the frequency and severity of migraines but also positively influenced the psychological aspects of living with migraines.
This suggests that incorporating EPA into migraine management could be a valuable option for those suffering from episodic migraines, especially as there were no major adverse effects reported.
After 12 weeks, the results were compelling. We noticed that those taking EPA had significantly fewer migraine days compared to the placebo group. In fact, participants on EPA reported an average reduction of 4.4 days per month, while those on the placebo had barely any change. The EPA group also experienced less need for acute headache medication and marked improvements in headache severity, disability, anxiety, depression, and overall quality of life.
Perhaps most striking was how particularly beneficial EPA seemed to be for female participants. Overall, the study demonstrated that high-dose EPA not only helped reduce the frequency and severity of migraines but also positively influenced the psychological aspects of living with migraines.
This suggests that incorporating EPA into migraine management could be a valuable option for those suffering from episodic migraines, especially as there were no major adverse effects reported.
10
Migraine relief
Most Useful Review
What a quality omega! The effect is highly noticeable, particularly on my skin. My migraine has disappeared.
Updated: Apr 2025
Ulcer details
SCIENTIFIC SCORE
Moderately Effective
Based on 25 Researches
8.5
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Eicosapentaenoic acid aids ulcer healing
We examined how Eicosapentaenoic acid (EPA) could protect against ulcerative colitis (UC), a chronic condition that inflames the large intestine. In our research, we used acetic acid to induce UC in rats, administering oral EPA for 28 days in doses of 300 and 1000 mg/kg before the acetic acid treatment.
Our findings were quite promising. EPA appeared to significantly alleviate UC symptoms, as seen in the improved colonic health of the rats. We noted that EPA treatment not only reduced inflammation but also helped restore the balance between oxidants and antioxidants in the body. This balance is crucial for maintaining a healthy gut environment and reducing tissue damage.
Moreover, EPA led to the enhancement of protective proteins in the colon, while it suppressed markers associated with inflammation. This included reductions in substances that typically signal more inflammation, which suggests that EPA has a dual role—enhancing protective factors while diminishing harmful responses. We believe these insights highlight the potential of EPA as a therapeutic agent for managing UC more effectively.
Our findings were quite promising. EPA appeared to significantly alleviate UC symptoms, as seen in the improved colonic health of the rats. We noted that EPA treatment not only reduced inflammation but also helped restore the balance between oxidants and antioxidants in the body. This balance is crucial for maintaining a healthy gut environment and reducing tissue damage.
Moreover, EPA led to the enhancement of protective proteins in the colon, while it suppressed markers associated with inflammation. This included reductions in substances that typically signal more inflammation, which suggests that EPA has a dual role—enhancing protective factors while diminishing harmful responses. We believe these insights highlight the potential of EPA as a therapeutic agent for managing UC more effectively.
10
No more ulcers
Most Useful Review
Excellent! I've been taking this for three years now and haven't had any more mouth ulcers. The delivery is always prompt.
Updated: Apr 2025
Osteoporosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 26 Researches
7.7
USERS' SCORE
Good
Based on 10 Reviews
8.4
7
We examined the relationship between docosahexaenoic acid (DHA) and osteoporosis using a method called 2-sample Mendelian randomization. This approach allowed us to investigate if higher levels of DHA could be a risk factor for osteoporosis.
Our findings revealed a causal tie: increased blood levels of DHA were indeed linked to a higher risk of developing osteoporosis. Specifically, for each standard deviation increase in DHA levels, the risk for osteoporosis rose by nearly 10%. We found this connection to be statistically significant, with a P-value of 0.033.
However, it's important to point out that the genetic correlation between DHA and osteoporosis was weak, suggesting that this relationship might not be heavily influenced by our genes. While these results indicate that DHA levels are a risk factor for osteoporosis, the underlying mechanisms are still unclear, highlighting the need for further research in this area.
Our findings revealed a causal tie: increased blood levels of DHA were indeed linked to a higher risk of developing osteoporosis. Specifically, for each standard deviation increase in DHA levels, the risk for osteoporosis rose by nearly 10%. We found this connection to be statistically significant, with a P-value of 0.033.
However, it's important to point out that the genetic correlation between DHA and osteoporosis was weak, suggesting that this relationship might not be heavily influenced by our genes. While these results indicate that DHA levels are a risk factor for osteoporosis, the underlying mechanisms are still unclear, highlighting the need for further research in this area.
9
Prevents osteoporosis
Most Useful Review
1 people found this helpful
This Omega-3 fish oil, certified by IFOS, is extracted from wild Alaska pollock. Each capsule contains significant amounts of EPA and DHA. Its benefits include reducing cholesterol and triglycerides, managing blood pressure, preventing osteoporosis, and enhancing joint health. It’s recommended to take 1-2 capsules daily, and it’s a great value, currently on sale.
Updated: Mar 2026
Anxiety details
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.2
USERS' SCORE
Good
Based on 10 Reviews
8.3
8
DHA improves milk and reduces anxiety
We explored how supplementing obese mothers with docosahexaenoic acid (DHA) affects milk composition and the anxiety behavior of their offspring. In a study involving female Wistar rats, some were placed on a high-fat diet while others ate regular chow. We supplemented half of the mothers from one month before mating until they weaned their pups with DHA. The goal was to see if this supplementation could improve the quality of their milk and influence the anxiety levels of their babies.
Our findings indicated that the obese mother rats exhibited higher weight and fat levels and their milk contained less beneficial DHA but more corticosterone and leptin. Notably, their offspring showed a higher ratio of omega-6 to omega-3 fatty acids in the milk they consumed, which correlates to increased anxiety levels, especially in female pups. In contrast, those mothers who received DHA supplements had lower body weight and fat and produced milk with higher DHA content. Their offspring not only had a better balance of omega-6 to omega-3 fatty acids but also demonstrated reduced anxiety compared to those from mothers without supplementation.
Overall, this study highlights the significant positive impact of DHA supplementation during pregnancy and lactation in obese rats, as it not only improves the nutritional quality of their milk but also helps decrease anxiety levels in the offspring in a sex-dependent manner.
Our findings indicated that the obese mother rats exhibited higher weight and fat levels and their milk contained less beneficial DHA but more corticosterone and leptin. Notably, their offspring showed a higher ratio of omega-6 to omega-3 fatty acids in the milk they consumed, which correlates to increased anxiety levels, especially in female pups. In contrast, those mothers who received DHA supplements had lower body weight and fat and produced milk with higher DHA content. Their offspring not only had a better balance of omega-6 to omega-3 fatty acids but also demonstrated reduced anxiety compared to those from mothers without supplementation.
Overall, this study highlights the significant positive impact of DHA supplementation during pregnancy and lactation in obese rats, as it not only improves the nutritional quality of their milk but also helps decrease anxiety levels in the offspring in a sex-dependent manner.
9
Anxiety diminished
Most Useful Review
8 people found this helpful
It just works! I've tried every fish oil on the market but never found any benefits. After trying Sports Research fish oil, I noticed immediate relief from my knee pain and a remarkable improvement in my anxiety. My anxiety has lessened considerably since taking it, and I will never switch back to other brands.
Updated: Mar 2026
Arteriosclerosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.1
USERS' SCORE
Good
Based on 5 Reviews
8.3
9
We embarked on a quest to understand how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, can impact atherosclerosis, a condition where fatty deposits clog the arteries. Our focus was on a specially developed injectable formulation that delivers DHA directly to the site of arterial plaques.
Through our research, we discovered that this liposomal DHA formulation not only protects the compound but also enhances its effectiveness. When we administered it intravenously, DHA particles were specifically absorbed by macrophages—immune cells involved in the inflammation seen in atherosclerosis. This targeted delivery helps reduce inflammation and prevents the formation of foam cells, which are a hallmark of atherosclerotic plaques.
Furthermore, our analysis of the plaques revealed that the DHA treatment led to less macrophage infiltration and reduced lipid build-up, which improves overall plaque stability. In simpler terms, we observed that the treatment makes plaques less likely to rupture, which is critical in preventing serious cardiovascular problems. Additionally, sophisticated imaging techniques showed that DHA can help restore some of the healthy lipid profiles typical of earlier stages of plaque development.
In summary, using injectable DHA offers exciting potential for stabilizing arterial plaques and slowing down the progression of atherosclerosis. Given the importance of addressing this condition, our findings could pave the way for new therapeutic strategies to reduce the risk of heart-related issues.
Through our research, we discovered that this liposomal DHA formulation not only protects the compound but also enhances its effectiveness. When we administered it intravenously, DHA particles were specifically absorbed by macrophages—immune cells involved in the inflammation seen in atherosclerosis. This targeted delivery helps reduce inflammation and prevents the formation of foam cells, which are a hallmark of atherosclerotic plaques.
Furthermore, our analysis of the plaques revealed that the DHA treatment led to less macrophage infiltration and reduced lipid build-up, which improves overall plaque stability. In simpler terms, we observed that the treatment makes plaques less likely to rupture, which is critical in preventing serious cardiovascular problems. Additionally, sophisticated imaging techniques showed that DHA can help restore some of the healthy lipid profiles typical of earlier stages of plaque development.
In summary, using injectable DHA offers exciting potential for stabilizing arterial plaques and slowing down the progression of atherosclerosis. Given the importance of addressing this condition, our findings could pave the way for new therapeutic strategies to reduce the risk of heart-related issues.
7.5
Beneficial for heart
Most Useful Review
Omega-3 fatty acids in fish oil, particularly EPA and DHA, are advantageous for the heart and blood vessels. They assist in lowering blood lipids, lessening the risk of arteriosclerosis, and maintaining normal heart function.
Updated: Mar 2026
Bronchitis details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.8
USERS' SCORE
Good
Based on 2 Reviews
8.3
9
We explored the impact of docosahexaenoic acid (DHA) on bronchitis in infants through a multi-center study involving 325 participants. Infants were fed either formula enriched with DHA and arachidonic acid (ARA) or a control formula without these additions.
Our findings showed that infants consuming the formula with DHA/ARA had a notably lower incidence of bronchitis, alongside other respiratory illnesses, during their first year of life. Specifically, we observed a significant reduction in the odds of experiencing bronchitis—a 59% decrease compared to those not receiving these nutritional supplements.
Not only did DHA help in reducing the number of bronchitis cases, but it also played a role in reducing symptoms like cough and nasal congestion. The overall impression from the data indicates that incorporating DHA into infant formula could bolster the immune response and lessen common respiratory challenges faced by infants.
Deciding on a formula for our little ones can be daunting, but the evidence suggests that choosing a DHA-enhanced option might provide valuable health benefits.
Our findings showed that infants consuming the formula with DHA/ARA had a notably lower incidence of bronchitis, alongside other respiratory illnesses, during their first year of life. Specifically, we observed a significant reduction in the odds of experiencing bronchitis—a 59% decrease compared to those not receiving these nutritional supplements.
Not only did DHA help in reducing the number of bronchitis cases, but it also played a role in reducing symptoms like cough and nasal congestion. The overall impression from the data indicates that incorporating DHA into infant formula could bolster the immune response and lessen common respiratory challenges faced by infants.
Deciding on a formula for our little ones can be daunting, but the evidence suggests that choosing a DHA-enhanced option might provide valuable health benefits.
7.5
Prevents bronchitis
Most Useful Review
Fish oil effectively protects the respiratory tract from infections, making it useful for preventing bronchitis. Additionally, it enhances antibody activity and stimulates the production of anti-inflammatory substances, thus benefiting overall health.
Updated: Apr 2025
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.9
USERS' SCORE
Good
Based on 15 Reviews
8.3
9.5
We explored the potential benefits of eicosapentaenoic acid (EPA), an essential fatty acid, in treating chronic fatigue syndrome (CFS). A female patient with a six-year history of persistent CFS symptoms participated in the study, receiving a daily supplement rich in EPA.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
After measuring her brain structure through high-resolution magnetic resonance imaging both at the beginning and 16 weeks later, we observed significant improvements in her symptoms starting just six to eight weeks into the treatment. Most notably, the patient's lateral ventricular volume—a key indicator of brain health—decreased from 28,940 mm³ to 23,660 mm³, indicating structural changes in her brain.
This research hints at the promising role of EPA in alleviating symptoms of chronic fatigue syndrome while also suggesting positive brain changes associated with treatment. The findings encourage further investigation into fatty acid supplementation's potential as an effective therapeutic strategy for CFS.
9
Fatigue disappeared
Most Useful Review
103 people found this helpful
Excellent value for money and quality! I have taken this omega for over a month and it's given me a remarkable boost in energy throughout the day! As a parent, sleepless nights leave me feeling broken, but since I started this omega, my fatigue has vanished! Additionally, it has improved my skin and nails significantly!
Updated: Mar 2026
Common Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.3
8
We conducted a double-blind randomized controlled trial to understand how prenatal supplementation of docosahexaenoic acid (DHA) might influence infant health, particularly concerning the common cold. Pregnant women were given either a daily dose of 400 mg of DHA or a placebo starting at 18 to 22 weeks of gestation until childbirth.
Caregivers then reported on their infants’ health at 1, 3, and 6 months, sharing details about common illness symptoms. We found that DHA supplementation appeared to reduce the number of colds at one month and also seemed to lessen the duration of various cold symptoms in infants. Specifically, infants in the DHA group experienced fewer cold symptoms and had shorter durations of cough and wheezing.
While the overall occurrence of specific illness symptoms was similar between the DHA and placebo groups, DHA did bring about noteworthy benefits. At 1 month, infants in the DHA group had a 26% shorter duration of cough and 30% shorter wheezing; however, they experienced a longer duration of rash.
Furthermore, by the time the infants reached 3 months, those whose mothers took DHA were ill for 14% less time overall. At 6 months, the DHA group showed significantly reduced durations of several illness indicators, although they did experience longer episodes of vomiting.
This study suggests that prenatal DHA not only seems to impact the occurrence of colds in children but may also play a role in the duration of symptoms over the first half-year of life.
Caregivers then reported on their infants’ health at 1, 3, and 6 months, sharing details about common illness symptoms. We found that DHA supplementation appeared to reduce the number of colds at one month and also seemed to lessen the duration of various cold symptoms in infants. Specifically, infants in the DHA group experienced fewer cold symptoms and had shorter durations of cough and wheezing.
While the overall occurrence of specific illness symptoms was similar between the DHA and placebo groups, DHA did bring about noteworthy benefits. At 1 month, infants in the DHA group had a 26% shorter duration of cough and 30% shorter wheezing; however, they experienced a longer duration of rash.
Furthermore, by the time the infants reached 3 months, those whose mothers took DHA were ill for 14% less time overall. At 6 months, the DHA group showed significantly reduced durations of several illness indicators, although they did experience longer episodes of vomiting.
This study suggests that prenatal DHA not only seems to impact the occurrence of colds in children but may also play a role in the duration of symptoms over the first half-year of life.
7.5
Effective for skin
Most Useful Review
1 people found this helpful
I recommend this product. It’s a decent drug at an attractive price compared to others. The PUFA content is optimal; I only need one tablet daily, which is very convenient. The composition is excellent for immunity and for skin, hair, and nails. My nails stopped peeling after two months of use—an issue unresolved for over two years. Plus, my skin has cleared, with all blemishes and inflammations in the décolleté area disappearing. A solid product with effective results!
Updated: Mar 2026
Food Poisoning details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 2 Reviews
8.3
9
We explored the effects of docosahexaenoic acid (DHA) on cadmium (Cd) exposure, a common pollutant that risks human health through the food chain. Our investigation focused on how DHA might help mitigate the harmful effects of Cd, particularly by looking at changes in gut microbiota.
The study involved examining mice that had been exposed to cadmium. We observed that DHA significantly boosted the amount of cadmium expelled in feces while reducing the levels of cadmium accumulated in various organs. Our findings highlighted a particularly encouraging increase in Parabacteroides, a beneficial bacteria in the gut that appeared to play a crucial role in this process.
We noted that the representative strain of Parabacteroides not only demonstrated the ability to reduce Cd toxicity but also helped repair gut damage inflicted by cadmium exposure. Furthermore, DHA effectively reduced cadmium levels in organs such as the liver, spleen, and kidneys, leading to a noticeable increase in cadmium excretion.
Overall, our results suggest that DHA may have significant potential in promoting the excretion of cadmium in instances of exposure. This insight offers a fascinating avenue for considering DHA as a supportive treatment option for handling heavy metal toxicity.
The study involved examining mice that had been exposed to cadmium. We observed that DHA significantly boosted the amount of cadmium expelled in feces while reducing the levels of cadmium accumulated in various organs. Our findings highlighted a particularly encouraging increase in Parabacteroides, a beneficial bacteria in the gut that appeared to play a crucial role in this process.
We noted that the representative strain of Parabacteroides not only demonstrated the ability to reduce Cd toxicity but also helped repair gut damage inflicted by cadmium exposure. Furthermore, DHA effectively reduced cadmium levels in organs such as the liver, spleen, and kidneys, leading to a noticeable increase in cadmium excretion.
Overall, our results suggest that DHA may have significant potential in promoting the excretion of cadmium in instances of exposure. This insight offers a fascinating avenue for considering DHA as a supportive treatment option for handling heavy metal toxicity.
7.5
Effective for family
Most Useful Review
3 people found this helpful
SUPER! Super omega for my family! I, my husband, and my 11-year-old son take one capsule in the morning with food. It contains a high dosage of essential acids EPA + DHA 995 mg in one capsule! I recommend this prophylactic dosage for everyone over 8-10 years old. With 180 capsules, it offers good value for a month's supply. The raw materials come from preferred small fish like anchovies, sardines, and mackerel. This product has been tested and confirmed to effectively lower cholesterol. A definite recommendation! Thank you for the like :)
Updated: Apr 2025
Hypothyroidism details
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7
USERS' SCORE
Good
Based on 5 Reviews
8.3
9
We set out to investigate how hypothyroidism affects cognitive function and whether omega-3 could provide a helpful boost in adult male rats. The study involved thirty rats, split into three groups: one as a control, another experiencing hypothyroidism, and the last group receiving omega-3 treatment.
The findings were quite striking. Rats with induced hypothyroidism showed significant memory problems, including difficulties in spatial learning and retention in various tests. These deficits were accompanied by lower levels of important brain chemicals and noticeable structural damage in the hippocampus, a key area for memory.
However, when we provided omega-3 supplements to one group, there was a remarkable turnaround. Those rats not only saw improvements in their memory but also regained some brain health. Omega-3 helped boost antioxidant levels, lessen structural issues in the brain, and reduce the expression of a protein linked to these damages.
All in all, our research suggests that omega-3 may serve as a protective ally against the cognitive challenges posed by hypothyroidism. This offers an exciting avenue for potential treatments that could benefit not just rats but perhaps humans facing similar hormonal challenges.
The findings were quite striking. Rats with induced hypothyroidism showed significant memory problems, including difficulties in spatial learning and retention in various tests. These deficits were accompanied by lower levels of important brain chemicals and noticeable structural damage in the hippocampus, a key area for memory.
However, when we provided omega-3 supplements to one group, there was a remarkable turnaround. Those rats not only saw improvements in their memory but also regained some brain health. Omega-3 helped boost antioxidant levels, lessen structural issues in the brain, and reduce the expression of a protein linked to these damages.
All in all, our research suggests that omega-3 may serve as a protective ally against the cognitive challenges posed by hypothyroidism. This offers an exciting avenue for potential treatments that could benefit not just rats but perhaps humans facing similar hormonal challenges.
9
Softened dry skin
Most Useful Review
1 people found this helpful
I absolutely love this omega! After just a few days of taking it, the difference in my skin and nails is evident. My elbows, often very dry due to hypothyroidism, feel smoother and softer after using this omega. We take it as a family, and I appreciate that one capsule contains 1000 mg of essential fatty acids. The capsule is large but easy to swallow.
Updated: Mar 2026
Indigestion details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.3
9
No symptoms noted
Most Useful Review
Blood vessel health is essential! This high-purity IFOS 5 STAR oil aids with my triglycerides as I exercise. I take omega-3 after a light breakfast, and after 3 months, there has been no fish odour or indigestion.
Updated: Apr 2025
Kidney Stones details
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
We explored the effects of eicosapentaenoic acid, an omega-3 fatty acid, on urinary factors linked to the formation of calcium oxalate kidney stones. In our study, we had 15 healthy participants follow a standardized diet over several phases to assess how daily supplementation with eicosapentaenoic acid and docosahexaenoic acid influenced their urinary excretion of calcium and oxalate.
Initially, during a 5-day control phase, we collected daily urine samples and observed no changes in the urinary parameters. However, after 30 days of supplementation, we noted a significant decrease—23%—in the relative supersaturation of calcium oxalate, primarily due to reduced oxalate excretion. This suggests that the supplementation may lower the risk of stone formation by affecting how the body manages oxalate.
Our findings propose that long-term use of eicosapentaenoic acid could be beneficial for those prone to calcium oxalate stones. The beneficial effect appears to arise from changes at the cellular level, altering how oxalate is exchanged. In summary, eicosapentaenoic acid supplementation holds promise as a preventive measure against kidney stones for certain individuals.
Initially, during a 5-day control phase, we collected daily urine samples and observed no changes in the urinary parameters. However, after 30 days of supplementation, we noted a significant decrease—23%—in the relative supersaturation of calcium oxalate, primarily due to reduced oxalate excretion. This suggests that the supplementation may lower the risk of stone formation by affecting how the body manages oxalate.
Our findings propose that long-term use of eicosapentaenoic acid could be beneficial for those prone to calcium oxalate stones. The beneficial effect appears to arise from changes at the cellular level, altering how oxalate is exchanged. In summary, eicosapentaenoic acid supplementation holds promise as a preventive measure against kidney stones for certain individuals.
9
Inflammation reduction
Most Useful Review
Excellent! It has significantly reduced the inflammation in my kidney.
Updated: Apr 2025
Menopause details
SCIENTIFIC SCORE
Questionable
Based on 20 Researches
6.9
USERS' SCORE
Good
Based on 5 Reviews
8.3
9
We explored how docosahexaenoic acid (DHA), at a dosage of 625 mg, affects menopausal symptoms among perimenopausal women. Our study involved 42 participants who were assessed for various symptoms using the Kupperman Index, along with quality of life and sexual function measured through standardized scales.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
After six months of DHA treatment, the women reported significant improvements in menopause symptoms, as reflected in their Kupperman Index scores. Specifically, psychological aspects of quality of life showed remarkable enhancement, while physical aspects did not exhibit notable changes.
Additionally, we observed improvements in sexual function, with increases in the Female Sexual Function Index scores and decreases in the Female Sexual Distress Scale, particularly in areas related to arousal and lubrication. Interestingly, the auditory brainstem response also indicated lower wave latencies after treatment, suggesting potential positive effects on neuronal conduction in the auditory system.
Overall, our findings suggest that DHA can effectively help mitigate some perimenopausal symptoms, thereby improving women's quality of life and aspects of sexual health.
9
Skin improvement
Most Useful Review
1 people found this helpful
I've used this product for over 3 years, initially on my doctor's advice. The results have been significant with long-term use, as my skin and hair conditions have greatly improved. The dryness of mucous membranes, persistent since menopause, has vanished! The capsules are slightly large, but taking one daily is simple. I highly recommend it!
Updated: Mar 2026
Stroke details
SCIENTIFIC SCORE
Moderately Effective
Based on 18 Researches
8.1
USERS' SCORE
Good
Based on 6 Reviews
8.3
9
We investigated the relationship between eicosapentaenoic acid (EPA) levels and stroke risk by pooling data from 29 international studies, involving over 183,000 participants. Our goal was to understand how circulating and tissue omega-3 fatty acid levels, specifically EPA, affect the occurrence of different types of stroke, including total, ischemic, and hemorrhagic strokes.
Our findings revealed that higher levels of EPA are linked to a lower risk of both total and ischemic strokes. For participants who had the highest levels of EPA, there was a 17% lower incidence of total strokes compared to those with the lowest levels, and an 18% reduction in ischemic strokes. This suggests that increasing EPA intake could be beneficial in reducing the risk of these stroke types.
However, it's important to note that EPA showed no significant relationship with hemorrhagic stroke risk. This indicates that while EPA may help prevent some stroke types, it does not appear to reduce the risk of bleeding strokes. These results were consistent across various demographics, regardless of whether participants had a history of atrial fibrillation or existing cardiovascular disease. Overall, our study presents strong evidence that EPA can be a valuable addition to dietary strategies aimed at reducing stroke risks.
Our findings revealed that higher levels of EPA are linked to a lower risk of both total and ischemic strokes. For participants who had the highest levels of EPA, there was a 17% lower incidence of total strokes compared to those with the lowest levels, and an 18% reduction in ischemic strokes. This suggests that increasing EPA intake could be beneficial in reducing the risk of these stroke types.
However, it's important to note that EPA showed no significant relationship with hemorrhagic stroke risk. This indicates that while EPA may help prevent some stroke types, it does not appear to reduce the risk of bleeding strokes. These results were consistent across various demographics, regardless of whether participants had a history of atrial fibrillation or existing cardiovascular disease. Overall, our study presents strong evidence that EPA can be a valuable addition to dietary strategies aimed at reducing stroke risks.
9
Anti-inflammatory properties
Most Useful Review
In clinical trials, Omega-3s have demonstrated the ability to regulate blood pressure and reduce blood clotting, thus decreasing the risk of heart attacks and strokes. Furthermore, Omega-3s lower triglycerides, cholesterol levels, and exhibit anti-inflammatory and antiarrhythmic properties.
Updated: Mar 2026
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.3
9
Swelling improved
Most Useful Review
1 people found this helpful
Very satisfied! My pickled legs and swelling have improved significantly, and the mild constipation has vanished. There is no fishy smell or taste. I will purchase this again next time.
Updated: Mar 2026
Arthritis details
SCIENTIFIC SCORE
Possibly Effective
Based on 28 Researches
7.3
USERS' SCORE
Good
Based on 8 Reviews
8.2
8
We explored the effects of eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, on patients with rheumatoid arthritis (RA). This analysis gathered data from eighteen randomized controlled trials involving over a thousand RA patients, ensuring a comprehensive look at its impact.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement.
Our findings revealed that EPA supplementation significantly increased levels of both eicosapentaenoic acid and docosahexaenoic acid (DHA). Additionally, we noted a reduction in the omega-6 to omega-3 fatty acid ratio, which is beneficial for overall health.
Moreover, we observed that EPA led to a decrease in triglyceride levels and tender joint counts among RA patients. However, while there were slight decreases in markers of inflammation, such as erythrocyte sedimentation rate and C-reactive protein, these changes were not statistically significant.
Overall, our analysis supports the idea that EPA has positive effects on lipid profiles and joint tenderness for those with RA, although not all inflammatory markers showed significant improvement.
9
Inflammation reduced
Most Useful Review
3 people found this helpful
I love this product! I have suffered from severe rheumatoid arthritis (RA) for over 40 years. My pain levels on medication are horrific at times, ranging between 6 and 10. I tried various brands of fish oils over the years without success. My son, a bodybuilder, suggested I try Sports Research brand. I started a daily regimen, taking it twice a day with buttermilk. Initially, I didn’t expect any difference, but within a month, I noticed a significant reduction in inflammation throughout my body. I also suffer from four other forms of crippling arthritis.
Updated: Mar 2026
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.8
USERS' SCORE
Good
Based on 16 Reviews
8.2
We conducted a randomized, double-blind, placebo-controlled clinical trial to explore the effects of PEGlated nanoliposome of pistachio unsaturated oils on inflammation in multiple sclerosis (MS). During the study, we treated MS patients with these nanoliposomes enriched with eicosapentaenoic acid, a type of omega-3 fatty acid known for its potential health benefits.
After the treatment, we observed significant improvements in various markers of inflammation. Notably, the levels of docosahexaenoic and eicosapentaenoic acids increased, while the level of matrix metallopeptidase-9, an enzyme linked to inflammation, decreased. This shift indicates a favorable response in how the patients’ bodies were managing inflammation.
Moreover, we noted a Th2-biased response in cytokine levels, which typically suggests a less inflammatory environment. The results showed a significant reduction in the frequency of relapses, lower disability scores, and fewer T2 lesions in patients treated with the nanoliposomes. Overall, our findings suggest that eicosapentaenoic acid treatment may offer promising benefits for managing inflammation associated with multiple sclerosis.
After the treatment, we observed significant improvements in various markers of inflammation. Notably, the levels of docosahexaenoic and eicosapentaenoic acids increased, while the level of matrix metallopeptidase-9, an enzyme linked to inflammation, decreased. This shift indicates a favorable response in how the patients’ bodies were managing inflammation.
Moreover, we noted a Th2-biased response in cytokine levels, which typically suggests a less inflammatory environment. The results showed a significant reduction in the frequency of relapses, lower disability scores, and fewer T2 lesions in patients treated with the nanoliposomes. Overall, our findings suggest that eicosapentaenoic acid treatment may offer promising benefits for managing inflammation associated with multiple sclerosis.
9
Improved activity
Most Useful Review
6 people found this helpful
This quality Omega-3 fish oil is truly the best. I bought it for my son per our doctor's prescription due to his thyroid issues. After two months of use, there's a visible benefit: he’s more active and cheerful. An ultrasound showed commendable results for his thyroid, along with improved skin and hair health. His overall well-being has significantly improved. We’re satisfied and plan to order again.
Updated: Mar 2026
Bloating details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 16 Reviews
8.2
9
Weight loss achieved
Most Useful Review
16 people found this helpful
I lost weight, but that isn’t my main reason for taking it. I've struggled with obesity for over 50 years and have faced constant bloating, pressure, and discomfort in my stomach area for the last five years. After extensive research on how to alleviate the bloating and pain, I came across Omega-3 fatty acids. Though I consume 2500mg daily mixed into a protein shake, in just three months, I've lost 18 pounds. I no longer have bloating or pressure in my stomach, and my blood pressure has improved significantly.
Updated: Mar 2026
Cancer details
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.2
9
We explored the effects of eicosapentaenoic acid, a type of omega-3 fatty acid, on pancreatic cancer using a specially designed mouse model that closely mimics human disease. This model allowed us to examine how adding omega-3 to the diet could impact cancer progression.
Our findings revealed that a diet enriched with eicosapentaenoic acid led to a significant reduction in tumor size and metastasis to the lungs and liver. We also observed a trend toward improved survival rates in the mice that received this dietary intervention compared to those that did not.
Interestingly, the treatment not only changed the fatty acid profile in the tumors but also influenced certain cellular processes. We noted an increase in apoptosis, or programmed cell death, without affecting how fast the cancer cells were growing. Additionally, there was a marked decrease in tumor fibrosis associated with lower levels of Sonic Hedgehog, a key player in pancreatic cancer development.
Overall, our research suggests that eicosapentaenoic acid holds promise as a dietary intervention for cancer treatment, potentially opening new doors for incorporating nutritional strategies in managing pancreatic cancer.
Our findings revealed that a diet enriched with eicosapentaenoic acid led to a significant reduction in tumor size and metastasis to the lungs and liver. We also observed a trend toward improved survival rates in the mice that received this dietary intervention compared to those that did not.
Interestingly, the treatment not only changed the fatty acid profile in the tumors but also influenced certain cellular processes. We noted an increase in apoptosis, or programmed cell death, without affecting how fast the cancer cells were growing. Additionally, there was a marked decrease in tumor fibrosis associated with lower levels of Sonic Hedgehog, a key player in pancreatic cancer development.
Overall, our research suggests that eicosapentaenoic acid holds promise as a dietary intervention for cancer treatment, potentially opening new doors for incorporating nutritional strategies in managing pancreatic cancer.
9
Essential for family
Most Useful Review
Due to my family's struggles with cancer, I need to take high doses of fish oil, particularly those rich in EPA. Just one fish oil a day is manageable, especially for the elderly, and it is in an easily absorbed Tg form. I highly recommend it.
Updated: Mar 2026
Celiac details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 8 Reviews
8.2
9
Skin health improved
Most Useful Review
I regularly take omega-3, as it is an essential nutrient and regulates various body processes. Unfortunately, fish is rarely in my diet. Due to dry skin and low immunity, I turned to omega-3. After two months of using Sports Research, I’m thrilled with my results. Each capsule contains a potent dose of EPA and DHA sourced from Alaskan pollock. This product keeps my skin soft and pressure stable, enhancing my mood and activity levels. I highly recommend it!
Updated: Apr 2025
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.3
USERS' SCORE
Good
Based on 5 Reviews
8.2
8
We conducted a study to explore the effectiveness of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, in treating major depressive disorder (MDD). Over the course of 12 weeks, 60 participants suffering from MDD were divided into two groups: one received 3.2 grams of EPA daily, while the other group was given a placebo, which was soybean oil.
Throughout the study, we assessed the severity of depression using the Hamilton Rating Scale for Depression (HRSD). What we found was promising. The group taking EPA experienced significantly lower HRSD scores at various checkpoints—specifically at weeks 4, 6, 8, and 12—indicating a reduction in depressive symptoms. Although the rates of remission and response were higher in the EPA group compared to the placebo group, these findings did not achieve statistical significance.
Overall, while EPA shows potential as a treatment for depression, further research is needed to solidify its role. Our findings suggest that it may be an alternative option for MDD patients seeking additional treatment pathways.
Throughout the study, we assessed the severity of depression using the Hamilton Rating Scale for Depression (HRSD). What we found was promising. The group taking EPA experienced significantly lower HRSD scores at various checkpoints—specifically at weeks 4, 6, 8, and 12—indicating a reduction in depressive symptoms. Although the rates of remission and response were higher in the EPA group compared to the placebo group, these findings did not achieve statistical significance.
Overall, while EPA shows potential as a treatment for depression, further research is needed to solidify its role. Our findings suggest that it may be an alternative option for MDD patients seeking additional treatment pathways.
7.5
Supports depression relief
Most Useful Review
4 people found this helpful
Distinguished Reduces the risk of depression and anxiety, enhancing brain function significantly for concentration and memory. Omega 3 also promotes healthy skin and hair. These pills help reduce appetite during main meals, aiding weight loss likely through regulating serotonin, the hormone that controls appetite. This control can significantly reduce depression symptoms. Quality ingredients and excellent taste.
Updated: Apr 2025
Knee Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 6 Reviews
8.2
9
Fish oil improves knee function
We explored how fish oil, rich in docosahexaenoic acid (DHA), can impact knee pain, particularly for those suffering from osteoarthritis. In our study, we involved 75 participants, divided into three groups, each taking either 1,000 mg or 2,000 mg of fish oil daily for eight weeks. We carefully measured their knee pain and walking abilities before and after the supplementation.
The results were encouraging. Those who took fish oil reported notable improvements in knee performance and function compared to a control group. On a satisfaction scale, the average score was an impressive 9.06 out of 10! While most participants experienced the benefits of fish oil without complications, there was one case of hematuria that was unrelated to the treatment.
Overall, our findings suggest that taking 1,000 to 2,000 mg of fish oil daily can significantly enhance knee performance and is safe for individuals with mild to moderate knee osteoarthritis. However, it’s worth noting that increasing the dose beyond 1,000 mg didn't yield greater benefits.
The results were encouraging. Those who took fish oil reported notable improvements in knee performance and function compared to a control group. On a satisfaction scale, the average score was an impressive 9.06 out of 10! While most participants experienced the benefits of fish oil without complications, there was one case of hematuria that was unrelated to the treatment.
Overall, our findings suggest that taking 1,000 to 2,000 mg of fish oil daily can significantly enhance knee performance and is safe for individuals with mild to moderate knee osteoarthritis. However, it’s worth noting that increasing the dose beyond 1,000 mg didn't yield greater benefits.
7.5
Improved joint flexibility
Most Useful Review
730 people found this helpful
In my opinion, this is the best Omega 3 on the site; I only buy it in triglyceride form. It’s made from the carcasses of cold-water fish with a short life cycle and has a high concentration of polyunsaturated fatty acids EPA and DHA. The right fats help strengthen the immune system, improve brain activity, and benefit the skin, nails, and hair. From taking it, I’ve noticed an improvement in my knee joints (it’s easier to bend and unbend), and my skin has become more hydrated and elastic. There’s no aftertaste or unpleasant sensations. I feel better. A quality brand; I recommend it!
Updated: Mar 2026
Psoriasis details
SCIENTIFIC SCORE
Possibly Effective
Based on 26 Researches
7.2
USERS' SCORE
Good
Based on 5 Reviews
8.2
8
We aimed to understand how eicosapentaenoic acid (EPA) affects psoriasis, a skin condition known for causing redness, irritation, and thickened skin. By creating skin models that reflect both healthy and psoriatic conditions, we were able to assess the impact of EPA directly on lipid profiles—a key factor in skin health.
Our research revealed that in psoriatic skin models, there was a notable increase in certain fatty acids linked to inflammation, such as arachidonic acid (AA) and linoleic acid (LA). However, when we supplemented the media with EPA, we noticed a significant shift. The levels of beneficial omega-3 fatty acids, including EPA, docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA), rose in both epidermal and dermal tissues.
More importantly, the addition of EPA helped to balance the production of lipid mediators in the skin. We observed increases in several anti-inflammatory molecules, such as prostaglandin E (PGE) and 12-hydroxyeicosapentaenoic acid (12-HEPE), indicating a move toward a more stable and healthier skin environment. These results suggest that EPA could play an important role in managing psoriasis by promoting a healthier lipid balance in the skin, potentially easing symptoms and encouraging skin healing.
Our research revealed that in psoriatic skin models, there was a notable increase in certain fatty acids linked to inflammation, such as arachidonic acid (AA) and linoleic acid (LA). However, when we supplemented the media with EPA, we noticed a significant shift. The levels of beneficial omega-3 fatty acids, including EPA, docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA), rose in both epidermal and dermal tissues.
More importantly, the addition of EPA helped to balance the production of lipid mediators in the skin. We observed increases in several anti-inflammatory molecules, such as prostaglandin E (PGE) and 12-hydroxyeicosapentaenoic acid (12-HEPE), indicating a move toward a more stable and healthier skin environment. These results suggest that EPA could play an important role in managing psoriasis by promoting a healthier lipid balance in the skin, potentially easing symptoms and encouraging skin healing.
9
Improves skin health
Most Useful Review
Excellent! Omega 3 has many benefits: it helps treat psoriasis, improves brain activity, reduces weight, enhances eyesight, bolsters the immune system, and prevents cardiovascular diseases, among other advantages.
Updated: Mar 2026
Tendonitis details
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Good
Based on 3 Reviews
8.2
9
DHA improves Achilles tendon health
We explored the potential of docosahexaenoic acid (DHA) as a treatment for Achilles tendinopathy (AT), a condition that can cause significant pain and discomfort. In our study, we induced AT in rats using type I collagenase and then divided them into several groups, including one treated with collagen and two different doses of DHA. This approach allowed us to compare how well DHA performed against traditional collagen treatment over an eight-week period.
After analyzing the results, we observed that both doses of DHA led to improvements in tendon health, particularly in the biomechanical properties like ultimate tensile force (UTF) and stiffness. Notably, the higher dose of DHA showed the most significant impact, with marked reductions in inflammation markers and damage to tendon cells compared to untreated controls.
Histopathological evaluations revealed that while there was severe degeneration in the AT group, those treated with DHA exhibited healthier-looking tendon cells. This suggests that DHA could indeed serve as a beneficial alternative treatment for managing tendonitis, especially considering its strong anti-inflammatory effects. Overall, our findings support the notion that DHA may be an effective strategy for treating this challenging condition.
After analyzing the results, we observed that both doses of DHA led to improvements in tendon health, particularly in the biomechanical properties like ultimate tensile force (UTF) and stiffness. Notably, the higher dose of DHA showed the most significant impact, with marked reductions in inflammation markers and damage to tendon cells compared to untreated controls.
Histopathological evaluations revealed that while there was severe degeneration in the AT group, those treated with DHA exhibited healthier-looking tendon cells. This suggests that DHA could indeed serve as a beneficial alternative treatment for managing tendonitis, especially considering its strong anti-inflammatory effects. Overall, our findings support the notion that DHA may be an effective strategy for treating this challenging condition.
7.5
Reduces inflammation
Most Useful Review
Powerful and high-quality, this product meets the IFOS standard and offers a potent dosage. I find that two capsules daily provide sufficient EPA, which aids in diminishing inflammation (tendonitis) and alleviating issues like acne through omega-3 and omega-6 balance.
Updated: Apr 2025
Brain Tumor details
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
USERS' SCORE
Good
Based on 9 Reviews
8.1
8
We explored an innovative approach to treating glioblastoma, the most common malignant brain tumor, by utilizing docosahexaenoic acid (DHA) liposomes. These liposomes were created using a microfluidic system that allowed for fine-tuning various properties, which could enhance their effectiveness in targeting tumor cells.
Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.
Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.
Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
9
Visible health results
Most Useful Review
1 people found this helpful
This Omega-3 is truly remarkable! It boasts the best price-quality ratio and efficacy. A single capsule provides a daily dose, avoiding the need for multiple intakes—which I occasionally forget. I’ve purchased it for myself and my elderly parents. Notably, I have witnessed improvements in skin and hair, and these Omega-3 fatty acids are essential for our brain, enhancing memory and cognitive function significantly. I wholeheartedly recommend it!
Updated: Mar 2026
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.1
7.5
Reduced inflammation
Most Useful Review
9 people found this helpful
Omega-3 fatty acids, particularly from wild fish triglycerides, are essential for cellular development and brain function. Adding DHA and EPA to the diet has shown to lower chronic inflammatory activity. Research supports that omega-3 PUFAs improve blood rheology and platelet function. This omega supplement is easy to take daily, with a beneficial acid content of 937 mg, and I highly recommend it!
Updated: Apr 2025
Cold Sores details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 7 Reviews
8.1
9
Increased energy levels
Most Useful Review
3 people found this helpful
I bought this Omega 3 for my husband, and he finds it excellent. One capsule a day lasts two months. He used to suffer from frequent colds and fatigue during winter, but since taking Omega 3 consistently, he hasn’t fallen ill! His energy levels have greatly improved, and he appreciates its ease of use. We're definitely buying more!
Updated: Mar 2026
Diabetes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.1
7.5
Lowered diabetes index!
Most Useful Review
Elderly individuals consume these to effectively lower their diabetes index and significantly improve their test results.
Updated: Mar 2026
Hypertension details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.7
USERS' SCORE
Good
Based on 8 Reviews
8.1
9
Eicosapentaenoic acid benefits hypertension
We investigated the impact of eicosapentaenoic acid (EPA) on hypertension, a condition characterized by elevated blood pressure that can lead to serious health issues. The study focused on a special compound called 5,6-diHETE lactone (EPA-L), derived from EPA, which we observed to promote better blood vessel function. This compound was tested on hypertensive rats and showed a significant reduction in blood pressure.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health.
9
Essential for hypertension
Most Useful Review
Excellent! Omega-3 becomes an essential supplement after a certain age, particularly for individuals with hypertension.
Updated: Apr 2025
Obesity details
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.6
USERS' SCORE
Good
Based on 2 Reviews
8.1
8
In our exploration of omega-3 fatty acids, we aimed to understand how eicosapentaenoic acid (EPA), compared to α-linolenic acid (ALA), impacts obesity, particularly in a specific mouse model designed for this purpose. We fed both wildtype and delta-6 desaturase knockout (KO) mice a high-fat diet rich in different fats over a period of 21 weeks. These diets included lard, which contains no omega-3s, flaxseed (rich in ALA), and menhaden fish oil (rich in EPA and docosahexaenoic acid, DHA).
What we found was quite revealing. While the final body weights of the mice did not vary significantly, those fed menhaden oil experienced reduced epididymal white adipose tissue (eWAT) weight, smaller adipocyte sizes, and lower triacylglycerol (TAG) content compared to those on a lard diet. Interestingly, the eWAT of flaxseed-fed wildtype mice showed similar improvements as those on menhaden oil, but this positive effect did not extend to the KO mice, which exhibited characteristics more similar to the lard group.
It's important to note that despite these differences in adipose characteristics, we did not observe any changes in inflammatory markers between the different groups. This suggests that while a diet enriched in EPA/DHA may help reduce fat storage and cell size, it does not appear to influence inflammatory responses in this particular model of obesity. Overall, this study highlights the specific benefits of EPA/DHA in addressing obesity-related issues without exacerbating inflammation.
What we found was quite revealing. While the final body weights of the mice did not vary significantly, those fed menhaden oil experienced reduced epididymal white adipose tissue (eWAT) weight, smaller adipocyte sizes, and lower triacylglycerol (TAG) content compared to those on a lard diet. Interestingly, the eWAT of flaxseed-fed wildtype mice showed similar improvements as those on menhaden oil, but this positive effect did not extend to the KO mice, which exhibited characteristics more similar to the lard group.
It's important to note that despite these differences in adipose characteristics, we did not observe any changes in inflammatory markers between the different groups. This suggests that while a diet enriched in EPA/DHA may help reduce fat storage and cell size, it does not appear to influence inflammatory responses in this particular model of obesity. Overall, this study highlights the specific benefits of EPA/DHA in addressing obesity-related issues without exacerbating inflammation.
6
Recommended for women
Most Useful Review
The product is of high quality, and I purchased it at a discount. It is vital for women to pay attention to omega-3s, as excessive fats can lead to obesity; yet, this product contains less fat. I will share any information I find and evaluate sincerely. Wishing you happiness, my dear.
Updated: Apr 2025
Atrial Flutter details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 13 Reviews
8
7.5
Quick results noted
Most Useful Review
51 people found this helpful
I found this Omega-3 from "Sports Research" to be excellent value for money. Although I can't consume natural seafood daily, this supplement served as a great source of polyunsaturated fatty acids. After just two weeks of use, I noticed increased concentration during training, improved vision, and my arrhythmia, which was rare, began to diminish. I took one capsule during breakfast on rest days and added another during lunch on training days. The soft, pleasant fish oil capsules were easy to swallow without causing any side effects. I enthusiastically recommend this product!
Updated: Mar 2026
Blurred Vision details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 12 Reviews
8
9
Improved tiredness
Most Useful Review
5 people found this helpful
This omega stands out due to its high dosage and triglyceride form, promoting increased "good" cholesterol levels. Taking just one capsule per day avoids any fishy aftertaste, making it easy to swallow. I've experienced a notable rise in "good" cholesterol after using this omega, plus the benefit of reduced eye fatigue and dryness. The effects on heart and brain health are significant, making it a great choice for anyone seeking a quality omega for their loved ones, or simply for personal benefit.
Updated: Mar 2026
Nausea details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 12 Reviews
8
7
We conducted a retrospective cohort study to investigate the relationship between nausea and vomiting in pregnancy (NVP) and dysmenorrhea measured by a verbal rating scale. Our research included 443 pregnant women, divided into those experiencing NVP and a control group.
From our findings, we noticed a clear association between moderate to severe dysmenorrhea and a heightened risk of NVP, especially during the first trimester. This suggests that those with painful menstrual symptoms may face an increased likelihood of nausea and vomiting as part of their pregnancy experience.
Importantly, we also examined the impact of periconceptional supplementation with docosahexaenoic acid (DHA). Our results indicated that taking DHA could potentially lower the risk of NVP, offering a glimmer of hope for managing nausea during pregnancy. This suggests that combining DHA with standard prenatal care might be beneficial for those who struggle with these symptoms.
Overall, our study sheds light on the intricate connections between menstrual pain and pregnancy-related nausea, emphasizing the potential protective role of DHA in improving women's health during this time.
From our findings, we noticed a clear association between moderate to severe dysmenorrhea and a heightened risk of NVP, especially during the first trimester. This suggests that those with painful menstrual symptoms may face an increased likelihood of nausea and vomiting as part of their pregnancy experience.
Importantly, we also examined the impact of periconceptional supplementation with docosahexaenoic acid (DHA). Our results indicated that taking DHA could potentially lower the risk of NVP, offering a glimmer of hope for managing nausea during pregnancy. This suggests that combining DHA with standard prenatal care might be beneficial for those who struggle with these symptoms.
Overall, our study sheds light on the intricate connections between menstrual pain and pregnancy-related nausea, emphasizing the potential protective role of DHA in improving women's health during this time.
10
No nausea noted
Most Useful Review
Great, I don't experience any nausea and it's superb. I'm recommending it to those around me!
Updated: Apr 2025
Premenstrual Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 11 Reviews
8
7.5
Eases PMS symptoms
Most Useful Review
218 people found this helpful
Omega-3 is fantastic with a good dosage. It's very convenient to take one capsule; despite its size, it's easy to swallow. During the second phase of my cycle, I take two capsules, which makes my premenstrual syndrome pass more easily. My skin is also less dry, especially during the heating season.
Updated: Mar 2026
Rash details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 9 Reviews
8
9
Cleared my skin
Most Useful Review
6 people found this helpful
Fine. This is the best product for my omega-3 allergic rashes on my chin. It works wonders, leaving my face clean.
Updated: Apr 2025
Sleep Apnea details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 20 Reviews
8
8
We investigated how the omega-3 fatty acid docosahexaenoic acid (DHA) impacts the severity of obstructive sleep apnea (OSA) in 350 patients undergoing sleep studies. Our study aimed to determine if there is a relationship between the levels of DHA in red blood cells (RBC) and the severity of sleep apnea, categorized as none/mild, moderate, or severe based on apnea hypopnea index (AHI) scores.
Our findings revealed that lower levels of DHA are linked to more severe cases of OSA. For each standard deviation increase in DHA, patients were about 50% less likely to be classified in the severe apnea category. Specifically, we noted decreased odds of falling into the severe OSA group when DHA levels were higher, suggesting that DHA may play an important role in the severity of this condition.
These insights imply that maintaining healthy DHA levels could potentially influence OSA severity and could aid in developing treatment strategies. We believe that future research should explore the potential benefits of DHA supplementation for those suffering from sleep apnea.
Our findings revealed that lower levels of DHA are linked to more severe cases of OSA. For each standard deviation increase in DHA, patients were about 50% less likely to be classified in the severe apnea category. Specifically, we noted decreased odds of falling into the severe OSA group when DHA levels were higher, suggesting that DHA may play an important role in the severity of this condition.
These insights imply that maintaining healthy DHA levels could potentially influence OSA severity and could aid in developing treatment strategies. We believe that future research should explore the potential benefits of DHA supplementation for those suffering from sleep apnea.
9
Improved sleep quality
Most Useful Review
1 people found this helpful
I purchased this fish oil after thorough research. Since using it, my sleep has significantly improved. Previously, I found it difficult to fall asleep even when I felt tired. However, after just three days of taking this fish oil, I find myself falling asleep within ten minutes each night. I intend to continue using it.
Updated: Mar 2026
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
USERS' SCORE
Moderately Good
Based on 21 Reviews
7.9
9
Eicosapentaenoic acid influences clotting
We explored how eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, influences blood clotting processes. The interest in EPA grew substantially after the 1970s when researchers Dyerberg and Bang noted that Greenland Eskimos had lower rates of coronary disease linked to their diet rich in marine lipids.
Their findings suggested that the higher levels of EPA led to reduced platelet aggregation, which essentially means that the blood clots less easily. This anti-clotting effect is significant since blood clots can lead to serious health issues like heart attacks and strokes.
Although studies have shown these promising effects, it’s crucial to note that much of the initial acclaim came from dietary observations rather than controlled clinical trials. This means that while we can relate high EPA intake to lower health risks in specific populations, we still need more rigorous studies to fully understand the impact of EPA on blood clotting across diverse groups.
Their findings suggested that the higher levels of EPA led to reduced platelet aggregation, which essentially means that the blood clots less easily. This anti-clotting effect is significant since blood clots can lead to serious health issues like heart attacks and strokes.
Although studies have shown these promising effects, it’s crucial to note that much of the initial acclaim came from dietary observations rather than controlled clinical trials. This means that while we can relate high EPA intake to lower health risks in specific populations, we still need more rigorous studies to fully understand the impact of EPA on blood clotting across diverse groups.
7.5
Optimised skin texture
Most Useful Review
4 people found this helpful
The ideal daily vitamin dosage is contained in a plastic jar with protective mica on the lid. Upon the first inspection, I removed it. Its strict black design conveys a quality impression. The capsules are large, dense, and rich golden colour. There's no smell, which I appreciate! They are easy to swallow with water without feeling they are stuck in my throat. There’s no unpleasant burping or aftertaste after ingestion! I carefully monitor the results, particularly concerning dry skin on my elbows and legs. Without omega, my skin remains dry and requires moisturising. But with omega, my skin's condition normalises—it feels soft and delicate. I am unable to comment on its effects on heart health and blood vessels, though my blood pressure seems consistent for my age.
Updated: Mar 2026
Cardiovascular Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
USERS' SCORE
Moderately Good
Based on 18 Reviews
7.9
9
We explored the impact of eicosapentaenoic acid (EPA), a nutrient known for its heart benefits, on diabetic cardiomyopathy (DC), a condition leading to heart failure. Our study focused on diabetic mice and revealed that EPA plays a protective role against DC, particularly by reducing harmful M1-polarized macrophages in the heart.
In our experiments, we found that EPA not only reduces cardiomyocyte injury caused by M1-polarized macrophages but also encourages a shift in macrophages' behavior from M1 to a protective Mox state—not M2. This shift is crucial because Mox macrophages help mitigate the damage inflicted by their M1 counterparts.
We identified heme oxygenase 1 (HO-1) as a key player in maintaining the Mox phenotype. EPA promotes HO-1, which helps curb macrophage M1 polarization and the resulting cardiomyocyte injury. Interestingly, our findings also showed that EPA fosters this protective Mox polarization in monocyte-derived macrophages from diabetic patients, suggesting a broader application for this treatment strategy.
Overall, our study highlights the potential of EPA as a novel approach to combat diabetic cardiomyopathy, emphasizing the importance of macrophage Mox polarization in maintaining heart health in diabetes.
In our experiments, we found that EPA not only reduces cardiomyocyte injury caused by M1-polarized macrophages but also encourages a shift in macrophages' behavior from M1 to a protective Mox state—not M2. This shift is crucial because Mox macrophages help mitigate the damage inflicted by their M1 counterparts.
We identified heme oxygenase 1 (HO-1) as a key player in maintaining the Mox phenotype. EPA promotes HO-1, which helps curb macrophage M1 polarization and the resulting cardiomyocyte injury. Interestingly, our findings also showed that EPA fosters this protective Mox polarization in monocyte-derived macrophages from diabetic patients, suggesting a broader application for this treatment strategy.
Overall, our study highlights the potential of EPA as a novel approach to combat diabetic cardiomyopathy, emphasizing the importance of macrophage Mox polarization in maintaining heart health in diabetes.
7.5
Supports cardiovascular health
Most Useful Review
327 people found this helpful
My choice! As a nutritionist, I am always studying, and this Omega is highly recommended by reputable functional medicine doctors. I suggest it to my clients and take it myself. It has a decent composition and provides excellent results in supporting cardiovascular health. A tip: to prevent omega-3 from oxidising in the body, take it alongside vitamin E. To check the quality of omega-3, cut the capsule and sniff or taste its contents; it should be fresh and pleasant without any rancid aftertaste. I’ve tested it and the quality is superb! Fresh fish oil inside! I highly recommend this manufacturer and hope my review helps you. Wishing you and your family good health.
Updated: Mar 2026
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 1 Research
5
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.9
5
Fatty acids affect IBS metabolism
Our study focused on understanding how eicosapentaenoic acid, alongside other fatty acids, influences irritable bowel syndrome (IBS). We designed an experiment where we treated both maternally separated and non-separated rats with Bifidobacterium breve and explored its effect on colonic sensitivity and fatty acid metabolism over a period of seven weeks.
Throughout our research, we observed significant changes in fatty acid profiles, especially in liver and serum tissues, after administering Bifidobacterium breve. Notably, in the maternally separated rats, the treatment appeared to enhance levels of palmitoleic acid, arachidonic acid, and docosahexaenoic acid in various tissues, which are fatty acids that others believe could be influential in managing symptoms related to IBS.
However, while eicosapentaenoic acid was present in the research context, it was largely studied in combination with other treatments. This made it challenging to evaluate its isolated effect on IBS directly. Thus, while we noted some positive metabolic changes with our treatment approach, the specific impact of eicosapentaenoic acid on IBS symptoms wasn’t definitively established.
Overall, our findings suggest that while Bifidobacterium breve and fatty acid supplementation may influence host fatty acid metabolism, further focused studies are necessary to clarify the role of eicosapentaenoic acid in managing irritable bowel syndrome.
Throughout our research, we observed significant changes in fatty acid profiles, especially in liver and serum tissues, after administering Bifidobacterium breve. Notably, in the maternally separated rats, the treatment appeared to enhance levels of palmitoleic acid, arachidonic acid, and docosahexaenoic acid in various tissues, which are fatty acids that others believe could be influential in managing symptoms related to IBS.
However, while eicosapentaenoic acid was present in the research context, it was largely studied in combination with other treatments. This made it challenging to evaluate its isolated effect on IBS directly. Thus, while we noted some positive metabolic changes with our treatment approach, the specific impact of eicosapentaenoic acid on IBS symptoms wasn’t definitively established.
Overall, our findings suggest that while Bifidobacterium breve and fatty acid supplementation may influence host fatty acid metabolism, further focused studies are necessary to clarify the role of eicosapentaenoic acid in managing irritable bowel syndrome.
9
Bowel movements improved
Most Useful Review
1 people found this helpful
As soon as I started taking it, my bowel movements improved and the odour disappeared. It's gotten so much better that I cannot live without it now.
Updated: Apr 2025
Pelvic Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 24 Reviews
7.9
9
Reduced bone pain
Most Useful Review
56 people found this helpful
These are the best Omega-3 pills I’ve tried. The dosage is 1250 mg, so I only take one pill daily. My bone pain has considerably diminished, and I highly recommend this product, as this is my second purchase.
Updated: Mar 2026
Rheumatoid Arthritis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 18 Reviews
7.9
9
Significant inflammation reduction
Most Useful Review
3 people found this helpful
I love this product! I have suffered from severe rheumatoid arthritis for over 40 years. My pain levels are often horrific while on medication. My son suggested I try Sports Research brand fish oil. Within a month, I noticed a tremendous reduction in inflammation throughout my body. It is working alongside my other medications. I hope to avoid the awful compression socks and shoes that used to alleviate my swelling.
Updated: Mar 2026
Cholecystitis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 6 Reviews
7.8
9
Liver support benefits
Most Useful Review
The supplement is beneficial for liver and gallbladder function. The liver can self-heal, but modern living hampers this. We purchased it for my mother-in-law, who has liver and gallbladder issues. She also takes milk thistle and reports feeling much better after using this supplement.
Updated: Apr 2025
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 25 Researches
7.3
USERS' SCORE
Moderately Good
Based on 97 Reviews
7.8
9
We explored the impact of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on heart disease through a significant study known as the VITAL trial. This study involved nearly 26,000 older adults in the U.S. and aimed to determine the effects of daily EPA supplementation on cardiovascular events over an average follow-up of 5.3 years.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
9
Reduced heart risks
Most Useful Review
6 people found this helpful
Awesome! I trust this brand, which has been reliable for years. My husband and I regularly take it to maintain our beauty, youth, and health, while significantly reducing the risk of heart disease. Symptoms of Omega-3 deficiencies are easily noticed, including dry skin and joint pain. Omega-3 significantly enhances blood circulation, brain function, and metabolism, besides having anti-inflammatory properties.
Updated: Mar 2026
Heartburn details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 10 Reviews
7.8
9
No heartburn experienced
Most Useful Review
8 people found this helpful
Great product. I only need one pill instead of three, with no aftertaste, burping, or heartburn. These are fantastic!
Updated: Mar 2026
Hives details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.8
2
Allergic reaction hives
Most Useful Review
I ordered Omega-3 to take with my parents, and it always arrives well-packaged. I chose it because I heard it reduces inflammation and bad cholesterol by improving blood. Unfortunately, I experience hives due to an allergic reaction when consuming it, and my parents only insist it is good for me. I wish I could enjoy it too. ðŸ˜
Updated: Mar 2026
Mild Cognitive Impairment details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.8
7.5
Reduces inflammation
Most Useful Review
After seeing the high ratings, I purchased two bottles. One is for my mother, who has early cognitive impairment. The omega-3 in fish oil nourishes the brain and helps lower cholesterol and inflammation. Although I have bone pain and lack appetite, the Haocai capsules are odourless. Food Club recommends them for my mother.
Updated: Mar 2026
Diarrhea details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.5
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.7
8
We examined how eicosapentaenoic acid, specifically a compound called 5,6-dihydroxy-8Z,11Z,14Z,17Z-eicosatetraenoic acid (5,6-DiHETE), affects diarrhea caused by inflammation in mice. In our study, the mice were given a substance that induces colitis, known as dextran sulfate sodium (DSS), and then treated with different doses of 5,6-DiHETE orally.
What we found was promising: the administration of both 150 and 600 micrograms of 5,6-DiHETE daily helped to speed up the recovery from diarrhea. After just a few days of treatment, we observed significant improvements in the mice’s condition. The daily doses led to less inflammation in the colon and a notable reduction in the symptoms of diarrhea associated with DSS-induced colitis.
We also measured how much of this compound remained in the mice's blood after taking it, finding that it peaked within half an hour of administration. This suggests that 5,6-DiHETE works relatively quickly to start affecting the inflammation. Overall, our research indicates that eicosapentaenoic acid holds potential as a beneficial treatment for inflammatory bowel diseases that cause diarrhea.
What we found was promising: the administration of both 150 and 600 micrograms of 5,6-DiHETE daily helped to speed up the recovery from diarrhea. After just a few days of treatment, we observed significant improvements in the mice’s condition. The daily doses led to less inflammation in the colon and a notable reduction in the symptoms of diarrhea associated with DSS-induced colitis.
We also measured how much of this compound remained in the mice's blood after taking it, finding that it peaked within half an hour of administration. This suggests that 5,6-DiHETE works relatively quickly to start affecting the inflammation. Overall, our research indicates that eicosapentaenoic acid holds potential as a beneficial treatment for inflammatory bowel diseases that cause diarrhea.
10
No diarrhea noted
Most Useful Review
Very good, no taste and no diarrhoea after eating.
Updated: Mar 2026
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 22 Researches
8
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.6
We uncovered intriguing insights into how eicosapentaenoic acid (EPA) and its metabolite, 12-hydroxyeicosapentaenoic acid (12-HEPE), play a role in managing allergic responses, particularly in the skin. Our study revealed that when mice consumed an omega-3 fatty acid-rich diet, 12-HEPE became a significant metabolite in their skin.
Interestingly, we observed that the enzymes responsible for producing 12-HEPE were more active in the skin compared to other organs. This effective metabolite appeared to reduce inflammation caused by contact hypersensitivity. Specifically, we found that applying 12-HEPE topically limited the influx of neutrophils, a type of white blood cell involved in inflammatory responses.
Taking our research a step further, we investigated the effects of 12-HEPE on human skin cells, or keratinocytes, in lab conditions. Our findings showed that 12-HEPE inhibited two specific genes that cause neutrophils to be attracted to the site of inflammation, showcasing its potential as a therapeutic agent for allergy management. Overall, we identified 12-HEPE as a potent metabolite in the skin, suggesting that dietary omega-3 fatty acids could be a beneficial strategy in controlling allergic reactions.
Interestingly, we observed that the enzymes responsible for producing 12-HEPE were more active in the skin compared to other organs. This effective metabolite appeared to reduce inflammation caused by contact hypersensitivity. Specifically, we found that applying 12-HEPE topically limited the influx of neutrophils, a type of white blood cell involved in inflammatory responses.
Taking our research a step further, we investigated the effects of 12-HEPE on human skin cells, or keratinocytes, in lab conditions. Our findings showed that 12-HEPE inhibited two specific genes that cause neutrophils to be attracted to the site of inflammation, showcasing its potential as a therapeutic agent for allergy management. Overall, we identified 12-HEPE as a potent metabolite in the skin, suggesting that dietary omega-3 fatty acids could be a beneficial strategy in controlling allergic reactions.
9
Resolved allergies
Most Useful Review
10 people found this helpful
I bought this on my doctor's recommendation. After taking it for three months, my body returned to normal and I had no allergies. I gave it three stars to keep the price down, but the brand is excellent!
Updated: Mar 2026
Back Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.5
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.6
9
Eicosapentaenoic acid alleviates back pain
We explored how eicosapentaenoic acid (EPA) might help in treating intervertebral disc degeneration (IDD), a major contributor to back pain. Research highlights that this condition often involves endoplasmic reticulum (ER) stress and breakdown of the extracellular matrix (ECM), key processes that worsen IDD. Our investigation demonstrated that EPA can promote autophagy, a process that helps cells clean up and maintain balance within the ECM.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
Through our experiments, we treated nucleus pulposus cells—cells in the discs that often suffer from degeneration—with EPA. We observed that EPA not only boosted autophagy but also suppressed the harmful effects of ER stress, reducing cell death and limiting ECM degradation. Additionally, we utilized a rat model of IDD to see if these protective effects translated into a real-world setting. The findings indicated that EPA improved the health of the discs and effectively slowed down the progression of IDD in these rats.
In summary, this research highlights the potential of EPA as a therapeutic option for managing back pain related to disc degeneration. Our results suggest that EPA could play an important role in supporting the health of intervertebral discs and mitigating some of the common issues associated with chronic back pain.
9
Reduced inflammation
Most Useful Review
3 people found this helpful
I have suffered from severe rheumatoid arthritis for over 40 years, with pain levels often between 6 and 10. My son suggested trying Sports Research brand omega-3 fish oil, which I commenced taking twice daily. Within a month, I noticed a considerable reduction in inflammation throughout my body, including my painfully swollen ankles. Thanks to this product, I hope to avoid returning to uncomfortable footwear meant to reduce swelling.
Updated: Apr 2025
Liver Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 28 Researches
7.7
USERS' SCORE
Moderately Good
Based on 6 Reviews
7.6
9
We investigated the potential of DHA-enriched phosphatidylserine (DHA-PS) in addressing liver injuries caused by cyclophosphamide in mice. By administering cyclophosphamide over five days, we created a model to simulate this liver damage. Following this, we treated the mice with different doses of DHA-PS for a week to see if it could help heal their livers.
Our findings were quite promising. The mice receiving DHA-PS experienced significant improvements in key liver health indicators, including reduced inflammation and oxidative stress. Through advanced analysis, we discovered that DHA-PS helped correct metabolic imbalances caused by cyclophosphamide, which is a crucial aspect of liver recovery.
Additionally, we observed that DHA-PS has a positive impact on the gut-liver axis. This treatment restored the intestinal barrier, reduced harmful compounds in the bloodstream, and improved overall gut microbiota health. By balancing the gut bacteria, we enhanced the overall health of the mice.
Overall, the results suggest that DHA-PS could be a valuable therapeutic option or functional food for combating liver injuries related to cyclophosphamide. This study highlights the potential benefits of DHA on liver health and underscores the importance of the gut-liver connection.
Our findings were quite promising. The mice receiving DHA-PS experienced significant improvements in key liver health indicators, including reduced inflammation and oxidative stress. Through advanced analysis, we discovered that DHA-PS helped correct metabolic imbalances caused by cyclophosphamide, which is a crucial aspect of liver recovery.
Additionally, we observed that DHA-PS has a positive impact on the gut-liver axis. This treatment restored the intestinal barrier, reduced harmful compounds in the bloodstream, and improved overall gut microbiota health. By balancing the gut bacteria, we enhanced the overall health of the mice.
Overall, the results suggest that DHA-PS could be a valuable therapeutic option or functional food for combating liver injuries related to cyclophosphamide. This study highlights the potential benefits of DHA on liver health and underscores the importance of the gut-liver connection.
9
Liver index declining
Most Useful Review
I initially took this to alleviate dry eye syndrome, recommended by my doctor. While that didn't improve much, I did notice my liver index decreased significantly after consuming one can (90 pills). My total cholesterol varied slightly. I plan to continue with the next can and monitor for any further changes over three months.
Updated: Mar 2026
Dizziness details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.5
9
Dizziness relief
Most Useful Review
For over three days, my dizziness has consistently disappeared. I’ve been taking it regularly for more than three years, and due to family history, my ear tingling has also gone away. I am also using CoQ10, which has reduced inflammation in my shoulder and improved my arm movement. I intend to continue this regimen for its numerous benefits.
Updated: Mar 2026
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.1
9.5
We conducted a 12-week study to explore how eicosapentaenoic acid (EPA) affects individuals suffering from episodic migraines. In our trial, 70 participants were randomly split into two groups—one received 2 grams of fish oil with 1.8 grams of pure EPA daily, while the other group got a placebo made of soybean oil.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
The results were quite promising. Those taking EPA reported a significant reduction in the number of migraine days per month, averaging about 4.4 fewer days compared to just 0.6 fewer days in the placebo group. We also noticed a decline in the usage of medication to treat headache symptoms among those taking EPA.
Additionally, participants experienced less severe headaches and improved psychological wellbeing, as indicated by better scores in anxiety, depression, and overall quality of life measures. Notably, women seemed to benefit even more from EPA.
Overall, it appears that high-dose EPA can be an effective preventive treatment for episodic migraines, helping to ease frequency, severity, and even the emotional toll associated with chronic headaches. Importantly, the treatment was well tolerated, with no significant adverse effects reported.
10
Energy boost
Most Useful Review
1 people found this helpful
The best omega I've tried. Each capsule has a high concentration and is small, making it easy to swallow without any unpleasant taste. It's great for fitness enthusiasts, as it naturally boosts energy levels. Additionally, it has significantly helped with my headaches.
Updated: Apr 2025
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Medium or Average
Based on 17 Reviews
6.9
9
Improved memory
Most Useful Review
I bought the Sports Research fish oil supplement for my husband, and he is very satisfied. He reports improved memory and better self-expression. The fish oil pills are large, but he swallows them easily. It improves concentration and cognition, aiding correct thinking. They glide down the throat well and do not have the typical fishy aftertaste. A good purchase; I will order again.
Updated: Mar 2026
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