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Supplement Facts
Serving Size: 1 Soft Gel
Amount Per Serving
%DV
Vitamin D (as cholecalciferol)
100 mcg (4,000 IU)
500%
The product is found useful for the following medical conditions
Common Cold
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.9
USERS' SCORE
Good
Based on 4 Reviews
8.7
8
Vitamin D reduces cold severity
Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training.
Most Relevant Research
We explored the connection between vitamin D levels and the frequency of upper respiratory tract infections (URTI) in physically active individuals throughout different seasons. In our research, we observed over 1,600 military recruits during their basic training, noting that only 21% were vitamin D sufficient during winter. Alarmingly, those who had sufficient vitamin D levels were found to be 40% less likely to experience URTIs compared to their deficient counterparts, suggesting that maintaining adequate vitamin D may be crucial for better respiratory health during demanding training periods.
Building on these findings, we conducted a follow-up study with 250 recruits, where we implemented various vitamin D supplementation strategies. Participants received either a placebo, simulated sunlight exposure, or oral vitamin D3 supplementation. The results were promising: vitamin D helped alleviate the severity of URTI symptoms and significantly reduced the number of days experiencing a cold. Notably, both sunlight and dietary supplementation were equally effective in boosting vitamin D levels and improving outcomes.
Overall, achieving vitamin D sufficiency can markedly reduce the burden of URTIs, particularly in physically demanding scenarios such as military training.
Building on these findings, we conducted a follow-up study with 250 recruits, where we implemented various vitamin D supplementation strategies. Participants received either a placebo, simulated sunlight exposure, or oral vitamin D3 supplementation. The results were promising: vitamin D helped alleviate the severity of URTI symptoms and significantly reduced the number of days experiencing a cold. Notably, both sunlight and dietary supplementation were equally effective in boosting vitamin D levels and improving outcomes.
Overall, achieving vitamin D sufficiency can markedly reduce the burden of URTIs, particularly in physically demanding scenarios such as military training.
10
Significant immune boost
Most Useful Review
Since adding this supplement to my routine, I've noticed a significant improvement in my immune health. I've not experienced a cold since starting it, which feels like a major success for me.
Acne
SCIENTIFIC SCORE
Questionable
Based on 14 Researches
6.9
USERS' SCORE
Good
Based on 1 Review
8.6
8
Vitamin D's effect on acne
Association between Vitamin D Level and Acne, and Correlation with Disease Severity: A Meta-Analysis.
Most Relevant Research
We examined how vitamin D levels relate to acne and the potential connection with acne severity. By analyzing data from various studies, we found that 1,362 individuals with acne were compared against 1,081 healthy controls.
Our findings revealed that those with acne had significantly lower vitamin D levels compared to the healthy participants. Additionally, vitamin D deficiency was more prevalent among acne sufferers. Interestingly, we also observed a negative correlation between vitamin D levels and acne severity, suggesting that lower levels of this vitamin might be associated with more severe acne.
This evidence points to the possibility that vitamin D plays a role in acne development. However, while our results are compelling, they encourage further investigation into how vitamin D might influence acne severity and whether its supplementation could be beneficial for those affected by this condition.
Our findings revealed that those with acne had significantly lower vitamin D levels compared to the healthy participants. Additionally, vitamin D deficiency was more prevalent among acne sufferers. Interestingly, we also observed a negative correlation between vitamin D levels and acne severity, suggesting that lower levels of this vitamin might be associated with more severe acne.
This evidence points to the possibility that vitamin D plays a role in acne development. However, while our results are compelling, they encourage further investigation into how vitamin D might influence acne severity and whether its supplementation could be beneficial for those affected by this condition.
10
Cured adult acne
Most Useful Review
This helped cure my adult acne and gave me energy! Two months ago, I visited the doctor regarding my adult acne and learned I was Vitamin D deficient. After switching to Carlson's Vitamin D3 supplements, I immediately noticed a difference. My acne is completely gone, including painful jawline cysts! I now take two softgels with breakfast, and I feel amazing.
Cold
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.8
USERS' SCORE
Good
Based on 1 Review
8.5
8
Vitamin D reduces cold severity
Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training.
Most Relevant Research
We explored the connection between vitamin D levels and upper respiratory tract infections (URTIs) among military recruits during their training. This observation spanned across different seasons and included over 1,600 recruits. Our aim was to understand how achieving sufficient vitamin D levels could potentially impact the frequency and severity of colds among physically active individuals.
In an additional phase of the research, we conducted a randomized controlled trial with 250 male recruits. They received either a placebo, simulated sunlight exposure, or oral vitamin D3 supplements during winter. This comparison allowed us to see if these methods effectively increased vitamin D levels to a sufficient status of 25(OH)D at 50 nmol/L or higher.
Notably, our findings showed that only 21% of recruits had adequate vitamin D during winter, yet those who did were 40% less likely to suffer from URTIs. Furthermore, both vitamin D supplementation strategies similarly helped nearly all participants achieve sufficient levels. Vitamin D supplementation notably reduced the severity of URTI symptoms by 15% and the number of days with URTIs by 36% compared to placebo.
While the supplementation strategies did not significantly alter other immune factors, such as salivary secretory immunoglobulin A, the overall reduction in respiratory infections indicates a beneficial effect of maintaining vitamin D sufficiency during military training.
In an additional phase of the research, we conducted a randomized controlled trial with 250 male recruits. They received either a placebo, simulated sunlight exposure, or oral vitamin D3 supplements during winter. This comparison allowed us to see if these methods effectively increased vitamin D levels to a sufficient status of 25(OH)D at 50 nmol/L or higher.
Notably, our findings showed that only 21% of recruits had adequate vitamin D during winter, yet those who did were 40% less likely to suffer from URTIs. Furthermore, both vitamin D supplementation strategies similarly helped nearly all participants achieve sufficient levels. Vitamin D supplementation notably reduced the severity of URTI symptoms by 15% and the number of days with URTIs by 36% compared to placebo.
While the supplementation strategies did not significantly alter other immune factors, such as salivary secretory immunoglobulin A, the overall reduction in respiratory infections indicates a beneficial effect of maintaining vitamin D sufficiency during military training.
8.8
Thwarted cold effectively
Most Useful Review
This is the most economical source for quality Vitamin D3. Living in a sunny climate, I supplement during winter when sunlight is limited. I found that taking this brand, Carlson, leads to fewer colds than usual. This year, I am comparing it with another brand. We started taking Vitamin D3 and magnesium as soon as they arrived, and they directly thwarted a cold that was progressing, halting the beginnings of feeling unwell for two of us.
Flu
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7
USERS' SCORE
Good
Based on 1 Review
8.5
8
Vitamin D reduces flu risk
Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
Most Relevant Research
We explored the potential benefits of vitamin D supplementation for reducing the risk of influenza infections. Through a comprehensive analysis of multiple Randomized Controlled Trials (RCTs), we aimed to clarify whether taking vitamin D can help prevent the flu.
Our investigation identified 10 relevant trials that included a total of 4,859 participants. These studies varied in their dosages and duration of vitamin D use, allowing us to assess overall effectiveness across different populations.
The findings were encouraging: our analysis demonstrated that vitamin D supplementation appears to significantly reduce the risk of getting influenza, suggesting that those who increase their vitamin D intake might be better protected during flu season.
Importantly, we did not find significant differences between the studies that could affect our result, and there was no hint of publication bias. Consequently, we can confidently suggest that including vitamin D in our health strategies could enhance our defenses against the flu.
Our investigation identified 10 relevant trials that included a total of 4,859 participants. These studies varied in their dosages and duration of vitamin D use, allowing us to assess overall effectiveness across different populations.
The findings were encouraging: our analysis demonstrated that vitamin D supplementation appears to significantly reduce the risk of getting influenza, suggesting that those who increase their vitamin D intake might be better protected during flu season.
Importantly, we did not find significant differences between the studies that could affect our result, and there was no hint of publication bias. Consequently, we can confidently suggest that including vitamin D in our health strategies could enhance our defenses against the flu.
8.8
More energy gained
Most Useful Review
This great supplement has worked wonders for me! I drive a cab at night in NYC and felt quite low, getting colds even after the flu shot. Since I began taking D-3 three or four times a week, I’ve felt much better. My appearance has improved and I have more energy than before.
Skin Cancer
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 1 Review
8.5
8
Vitamin D's effect on BCC treatment
A Clinical Trial to Determine the Impact of Tumor Size, Histological Subtype, and Vitamin D Status on the Therapeutic Response of Basal Cell Carcinoma to Photodynamic Therapy.
Most Relevant Research
We conducted a clinical trial to understand how vitamin D might impact skin cancer treatment, specifically targeting basal cell carcinoma (BCC). In our study, 35 patients participated in an innovative approach where they received three sessions of photodynamic therapy (PDT) using a special light, after either taking high-dose vitamin D, a placebo, or having no pretreatment at all.
Using advanced 3D photography, we monitored the tumors throughout the treatment. We found that 70% of tumors cleared after PDT, but those that didn't respond often had aggressive histologic subtypes. Interestingly, the effectiveness of vitamin D seemed to relate to the tumor's depth. Among the tumors analyzed, thinner ones showed a 65% chance of responding to vitamin D, while thicker tumors had a much lower response rate of just 28%.
Overall, we discovered that vitamin D may be a beneficial supplement in enhancing the effects of PDT for suitable BCC lesions. These findings suggest a promising potential role for vitamin D in skin cancer therapy, making it an encouraging avenue for future exploration.
Using advanced 3D photography, we monitored the tumors throughout the treatment. We found that 70% of tumors cleared after PDT, but those that didn't respond often had aggressive histologic subtypes. Interestingly, the effectiveness of vitamin D seemed to relate to the tumor's depth. Among the tumors analyzed, thinner ones showed a 65% chance of responding to vitamin D, while thicker tumors had a much lower response rate of just 28%.
Overall, we discovered that vitamin D may be a beneficial supplement in enhancing the effects of PDT for suitable BCC lesions. These findings suggest a promising potential role for vitamin D in skin cancer therapy, making it an encouraging avenue for future exploration.
8.8
Remarkable vitamin levels
Most Useful Review
I take Vitamin D3 since being diagnosed with melanoma skin cancer around 10 years ago. My physician recently remarked on my Vitamin D level, noting it was unusually high for someone of my age and typical for teenagers. He advised me to continue taking this product.
