Supplement Facts
Serving Size: 1 tablet
Amount Per Serving
%DV
Selenium (as L-selenomethionine)
100 mcg
182%

The product is found useful for the following medical conditions

Allergies details

SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.2
USERS' SCORE
Good
Based on 4 Reviews
8.6
We examined how selenium, a trace element known for its role in health, can help those suffering from allergic dermatitis. In our exploration, we focused on how selenium nanoparticles, specifically designed for easier manufacturing and use, can activate the body's natural defenses against allergies.

The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.

Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.

Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.
9
Effective against allergies
Most Useful Review
18 people found this helpful
Great product! It is well absorbed and does not cause allergies. Thank you, iHerb!

Autoimmune Disorder details

SCIENTIFIC SCORE
Questionable
Based on 17 Researches
6.9
USERS' SCORE
Good
Based on 5 Reviews
8.6
We explored how selenium supplementation might help individuals suffering from Graves' orbitopathy, an autoimmune disorder linked to thyroid dysfunction. Our approach involved a systematic review and meta-analysis that assessed results from four randomized controlled trials.

The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.

We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.

Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.
9
Cysts disappeared
Most Useful Review
7 people found this helpful
The doctor prescribed selenium, so I ordered it along with iodine from Iherb for better quality. I take 200 micrograms of selenium and three drops of iodine. After six months, I had a follow-up ultrasound and the cysts in my mammary glands have disappeared. These cysts formed due to iodine deficiency, so it's essential to replenish selenium first to ensure iodine isn't toxic. I'm happy with the outcome—thank you for the thumbs up!

Hair Loss details

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Good
Based on 5 Reviews
8.6
We conducted a randomized double-blind, placebo-controlled trial to explore how selenium supplementation may influence hair loss among women with polycystic ovary syndrome (PCOS). In the study, 64 women aged 18-40 received either 200 μg of selenium daily or a placebo for eight weeks.

After the treatment period, we noticed a significant improvement in hair-related issues for those taking selenium. Specifically, alopecia rates dropped from 40.6% in the selenium group to just 9.4% in the placebo group, showing a strong positive effect of the supplement on hair loss. Acne also improved, with a reduction from 46.9% to 12.5%.

Furthermore, women who took selenium supplements exhibited decreased levels of dehydroepiandrosterone (DHEA), hirsutism, and markers of inflammation and oxidative stress. However, it’s important to note that selenium did not show significant effects on some hormonal profiles and other biomarkers. Overall, our findings suggest that selenium can be beneficial for women with PCOS, particularly regarding hair loss and related symptoms.
9
Hair loss improvement
Most Useful Review
7 people found this helpful
Hair analysis indicated a deficiency in selenium. I chose this selenium due to its excellent dosage of 100 mcg. The tablets are small, round, and odourless, making them easy to swallow. There were no side effects. Alongside omega and vitamin D, the quality of my hair has improved significantly, and hair loss has practically ceased. I am very pleased with the results, and the jar lasts for several courses.

Celiac details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.5
9
Normalised thyroid function
Most Useful Review
Of the yeast-free options, this is the best. It's crucial to keep it out of the sun, as the plastic can become warm. I store it in the fridge to keep my child from accessing it. With gastritis, I required something gluten-free and yeast-free, and this one had the best composition. My thyroid function normalised within two weeks.

Ear Infection details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Temperature relief
Most Useful Review
After suffering from a high temperature for many years due to a herpes virus infection, it ceased following the use of selenium. This has lasted a year now. Initially, I was informed that the temperature was nerve-related, but I’ve learned that the thyroid regulates body temperature and selenium supports it. Hence, I will continue taking it for preventive purposes.

Brain Tumor details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
Prevents tumour development
Most Useful Review
I undergo courses and observe excellent results. Scientists recently discovered that low selenium levels in blood can trigger benign and malignant tumour development. Foods rich in selenium and vitamin E can prevent prostate cancer, while a combination of vitamin A, zinc, vitamin E, and selenium actively combats stomach cancer. They protect us from free radicals' damaging effects and are crucial for producing primary antioxidants.

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 4 Reviews
8.4
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
9
Effective for relapses
Most Useful Review
3 people found this helpful
Excellent! This supplement has significantly helped me with my chronic fatigue relapse.

Cold Sores details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.4
9
Highly effective
Most Useful Review
Wonderful! An effective supplement that is essential during a cold.

Hashimoto details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 6 Reviews
8.4
We examined the impact of selenium supplements on thyroid autoantibody levels in patients with Hashimoto's thyroiditis.

In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.

However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.

This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.
9
Balanced hormones
Most Useful Review
2 people found this helpful
It is crucial for my health. I have a thyroid issue (Hashimoto) but do not need to take additional hormone pills. Within 3-6 months, my hormone levels improved; I feel less tired and my weight is more balanced. My ultrasound showed that I no longer have thyroid nodules. The quality is excellent and the size is just right. Due to a lack of the iodine mineral, I use it daily.

Heart Attack details

SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.4
We examined the role of selenium in treating myocardial infarction (MI), a major cause of death worldwide that can lead to serious heart problems. The study focused on how this antioxidant works across different phases of a heart attack, where harmful reactive oxygen species (ROS) play a significant role in worsening the condition.

Our findings highlighted a new approach using selenium-embedded nanoparticles, which are specially designed to act as antioxidants at various stages of MI. This innovative method allows for selective ROS elimination when it's most needed, leading to impressive recovery outcomes for the heart.

Throughout the research, it became clear that these nanoparticles help protect vital functions in heart cells by reducing cell death, inflammation, and scar tissue, while also encouraging new blood vessel growth. Overall, this self-sustaining antioxidant strategy shows great potential, not just for treating heart attacks but also inspiring therapies for other ischemic conditions.
9
Prevents heart damage
Most Useful Review
2 people found this helpful
Excellent selenium! It supports the immune system, prevents ageing, and halts inflammatory processes. It strengthens blood vessels, protects the heart from damage, prevents viral mutation, and is crucial for the thyroid gland's function. My husband and I take one tablet for three months, followed by a break. A single can lasts us three months.

Hypothyroidism details

SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.6
USERS' SCORE
Good
Based on 9 Reviews
8.4
We explored the effects of selenium supplementation in patients suffering from Hashimoto thyroiditis (HT), a leading cause of hypothyroidism. By analyzing multiple randomized controlled trials, we aimed to see how selenium might impact thyroid function, particularly focusing on thyroid-stimulating hormone (TSH) levels and thyroid antibodies.

Our analysis included results from 35 studies, where we observed that selenium supplementation led to a notable decrease in TSH levels among patients not undergoing thyroid hormone replacement therapy. This suggests that selenium may help manage thyroid function in specific populations.

Additionally, we found that selenium also reduced levels of thyroid peroxidase antibodies (TPOAb) and malondialdehyde (MDA), which indicates improved thyroid health and reduced oxidative stress. Interestingly, we observed that these benefits occurred irrespective of whether patients were receiving thyroid hormone therapy.

However, we did not find significant changes in other thyroid hormones or immune markers, indicating that while selenium can be effective in some areas, its benefits may not extend across all measures of thyroid health. Overall, our findings support the safe use of selenium in lowering TSH and certain antibodies in HT patients not on hormone therapy.
9
Enhanced thyroid function
Most Useful Review
36 people found this helpful
One of the best options available, this version of selenium has a good reputation. The round tablets, covered with a thin soluble film, are easy to break in half. When initially opened, they have a typical supplement smell that fades quickly. The 100 mg dosage is quite convenient: I take two, while my husband takes one. For my child with ARVI, it offers additional support. Selenium is crucial for thyroid function and is essential for managing hypothyroidism, particularly when combined with zinc, iodine, and vitamins D3. This combination enhances strength, energy, and mood. Selenium also aids in converting the hormone T4 to T3, which is vital for proper health.

Nausea details

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 4 Reviews
8.4
This randomized, double-blind, crossover study explored how selenium impacts nausea and overall health in children and adolescents undergoing chemotherapy for leukemia, lymphomas, and solid tumors.

We noted a decrease in nausea and fatigue scores, particularly after a year of selenium supplementation in patients with solid tumors, suggesting it may alleviate some side effects of chemotherapy.

However, there were no significant changes for leukemia patients in nausea, despite improvements in fatigue and physical function. Overall, selenium supplementation shows promise in enhancing the quality of life for young cancer patients.
9
No nausea experienced
Most Useful Review
2 people found this helpful
Wonderful! A quality product. Acquired on the recommendation of an endocrinologist. The tablets are small, easy to take, did not cause nausea or discomfort in the stomach, the dosage is good, and the supply lasts for half a year. Another significant plus for me is the absence of yeast.

Blood Clot details

SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.3
We explored the effects of ebselen, a selenium compound known for its antioxidant properties, on blood clot formation in rats. Our study demonstrated that ebselen significantly delayed thrombus formation in microvessels.

In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.

This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
9
Significantly increased levels
Most Useful Review
Excellent selenium! After two months, my blood levels rose considerably. The tablets are small, thin, and easy to swallow. I highly recommend them.

Bone Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
7.5
Bone density improved
Most Useful Review
The quality is remarkable. We take 200 mg in the morning with food for 3 months. This micronutrient significantly benefits women: it lowers the risk of osteoporosis and bone density loss post-menopause, prevents dry mucous membranes by influencing hormone production, strengthens blood vessels, and reduces cholesterol plaque risks. It possesses anti-inflammatory properties, supports the endocrine system's functions, and aids in muscle cell regeneration and skin restoration.

Chronic Cough details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
Enhanced immunity
Most Useful Review
Excellent vitamin! We purchased a large package and my whole family, all adults, took it together. After the course, my work performance and immunity improved significantly. I went through the spring without any snot or cough, which is impressive. This yeast-free selenium is especially beneficial for allergy sufferers. The capsules are tasteless with no aftertaste, and the composition is great. We will definitely be buying more.

Menopause details

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.3
We investigated how diphenyl diselenide, a synthetic selenium compound, affects cognitive performance in a rat model of menopause. Female rats underwent ovariectomy, mimicking hormone loss in postmenopausal women, and were treated with diphenyl diselenide daily for 30 days.

The results showed that this treatment improved cognitive abilities, as evidenced by better performance in behavioral tests and prevented the increase of acetylcholinesterase activity.

Overall, diphenyl diselenide appears to hold promise in mitigating cognitive decline linked to menopause.
7.5
Delays menopause onset
Most Useful Review
2 people found this helpful
Good selenium for the body. Selenium directly affects hormones, benefitting women's health. Regular intake in adulthood can help delay menopause, allowing women to remain attractive longer. It is indispensable for hair, nails and skin health.

Sleep Apnea details

SCIENTIFIC SCORE
Questionable
Based on 1 Research
5
USERS' SCORE
Good
Based on 3 Reviews
8.3
We examined the levels of selenium and key vitamins in patients suffering from obstructive sleep apnea (OSA) without additional health issues. Our study, involving 146 subjects split into different OSA severity levels, aimed to understand how these antioxidants might play a role in OSA's impact on health.

Interestingly, we found that higher concentrations of selenium and vitamin A appeared to bolster the body’s defense against OSA. Although our findings suggest potential benefits, it's important to note that antioxidants alone should not replace conventional treatments for OSA.
9
Enhanced sleep experience
Most Useful Review
An excellent product that notably enhances my sleep quality and has a great quantity for the price.

Cold details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 14 Reviews
8.2
9
Indispensable supplement
Most Useful Review
Wonderful! It’s an effective supplement, indispensable during a cold.

Hypertension details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.2
7.5
Supports hypertension treatment
Most Useful Review
Selenium is necessary for arrhythmia, coronary heart disease, hypertension, and recovery after myocardial infarction. It normalises fat metabolism and cholesterol levels in the blood, and protects blood vessels and heart muscle from damage. The form is convenient, and the recommended selenium intake is 50–55 mcg per day, with a maximum permissible dose of 300-350 mcg, as prescribed by a doctor.

Whooping Cough details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.1
6
Boosted immunity
Most Useful Review
The vitamin is fantastic! We consumed it as a family (all adults). After taking it, my working capacity and immunity improved. We enjoyed a spring without snot or cough. It contains yeast-free selenium, which is essential for allergy sufferers. The capsules lack both taste and aftertaste, and the composition is commendable. We will certainly buy more.

Heart Disease details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.9
We explored how selenium nanoparticles (SeNPs) could help reduce damage from heart attacks, specifically ischemia/reperfusion injury (I/RI). Using a method to create these nanoparticles, we found they possess remarkable properties that combat oxidative stress and inflammation.

SeNPs seem to disrupt harmful cellular cycles, thereby protecting heart cells. Notably, they improved heart function and reduced cell death and scar tissue in tests. Overall, these findings suggest that SeNPs could be a valuable approach in managing heart conditions after a heart attack.
7.5
Prevents heart disease
Most Useful Review
5 people found this helpful
Selenium is a potent antioxidant that protects cells from free radicals. Excessive free radical formation due to smoking, alcohol, and stress leads to oxidative stress, damaging healthy cells and contributing to cardiovascular diseases. Studies indicate that a 50% increase in selenium levels in the blood correlates with a 24% reduction in coronary artery disease risk. It's also an anticarcinogen, proving effective against lung and breast cancer, and is vital for normal thyroid gland function, where selenium is most concentrated, playing a key role in hormone metabolism.

Cancer details

SCIENTIFIC SCORE
Moderately Effective
Based on 27 Researches
8.3
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.6
We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival.

The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells.

Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients.
7.5
Prevents cancer development
Most Useful Review
5 people found this helpful
Selenium fortifies the immune system and acts as a potent antioxidant, shielding cells from free radicals, which can be exacerbated by factors like smoking and stress. This mineral is linked to cardiovascular disease prevention, and studies indicate that a 50% increase in blood selenium correlates with a 24% drop in coronary artery disease. Its antitumor properties against lung and breast cancer are well-documented, and selenium is essential for proper thyroid function.
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