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Supplement Facts
Serving Size: 2 Caplets
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
2 g
1%¹
Dietary Fiber
1 g
4%¹
Selenium (from culture media)
100 mcg
182%
RM-10 Fermented Organic Mushroom BlendMaitake (Grifola frondosa) mycelia*, Shiitake (Lentinula edodes) mycelia*, Reishi (Ganoderma lucidum) mycelia*, Coriolus versicolor mycelia*, Bionectria ochroleuca mycelia, Wolfiporia cocos mycelia*, Hericium erinaceus mycelia*, Formitopsis cajanderi mycelia*, Annulohypoxylon stygium mycelia*, Agaricus blazei mycelia*
1.16 g
+
Cat's Claw (Uncaria tomentosa) Bark
240 mg
+
The product is found useful for the following medical conditions
Cold
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 10 Reviews
8.8
8.3
No cold caught
Most Useful Review
I've been taking Garden of Life Immune System RM-10, 120 Caps, with 6 pills a day for the last month mainly on an empty stomach. It seems to keep my immune system operating well, as my wife has had a dreadful cold for the past month and I remained unaffected. I've been surrounded by coughs at home and in the office but didn't catch a cold this time. My wife is now interested in taking some to aid her recovery. I would recommend these pills as they may help.
Cancer
SCIENTIFIC SCORE
Moderately Effective
Based on 46 Researches
8
USERS' SCORE
Good
Based on 11 Reviews
8.7
9.5
Selenium drug shows selective toxicity
Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy.
Most Relevant Research
We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival.
The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells.
Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients.
The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells.
Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients.
9.5
Strong immune support
Most Useful Review
RM-10 is an essential supplement for those with cancer or MS. For stage 3 or 4 breast cancer, one must take 10 to 20 pills three times a day. Having battled bladder cancer myself, I found that an alkaline diet alongside RM-10 was vital in achieving remission. Proper nutrition and supplements saved my life and kept my immune system strong during treatment.
Chemotherapy
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Makes chemotherapy bearable
Most Useful Review
These vitamins made my chemotherapy bearable. Following my initial round of treatment, I experienced extreme nausea and fatigue. However, with the addition of these vitamins in my second round, I had no nausea and regained energy, enabling me to eat normally. These vitamins boost T Cell presence, crucial during cancer treatment, and could potentially assist in the effectiveness of chemotherapy or radiation.
Ear Infection
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Virus prevention success
Most Useful Review
After a major surgery, my immune system crashed, leading to nonstop viruses for six months. My chiropractor recommended Rm-10 and monolaurin. After starting these supplements, I noticed that I could control my sinus infections; now, I clear them up in just a few days, thanks to Rm-10. I'm a loyal customer for life!
Flu
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 9 Reviews
8.6
9.5
No sniffles experienced
Most Useful Review
We are a large family (and because of cost, we are only taking half dose, 1 pill per day). We added this to our winter regimen this year. It's March first and we haven't had a sniffle. We were surrounded by people, many sick with flu at large organised events, and we even had guests in our home recovering from the flu. We'll finish this winter on this supplement and add it again next year. I'm very impressed!
Gout
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
10
No more gout attacks
Most Useful Review
From personal experience, this is a good immune system balancer. I suffered several gout attacks over the years, each progressively more prolonged and painful. After trying dietary changes and various remedies to no avail, I became quite frustrated. Unable to address the root cause of my ailment, I opted to treat the symptoms directly. The pain from gout stems from inflammation caused by the immune system's reaction to uric acid crystals. I have taken RM-10 for over a year now, and since starting it, I have not experienced a single gout attack. My theory is that it helps balance the immune system's overactivity responsible for gout attacks.
Nausea
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Chemo success
Most Useful Review
This truly makes chemotherapy bearable. During my first round, I experienced extreme nausea and no energy. The second round, I took three of these vitamins daily and had no nausea, plenty of energy, and was able to eat normally. These vitamins are essential alongside chemotherapy to support immune function, and they can even enhance treatment efficacy.
Bone Pain
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Reduced bone pain
Most Useful Review
Ok - I would recommend this for immune support; it has reduced my bone pain caused by PCOS.
Bacterial Infection
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.3
USERS' SCORE
Good
Based on 1 Review
8.5
9.5
Selenium bandages prevent infections
Selenium Bandages and Cotton Cloth That Kill Microorganisms in Wounds.
Most Relevant Research
We investigated how selenium-infused bandages can help prevent bacterial infections in wounds. By attaching organo-selenium compounds to cotton fabric, we created a bandage designed to kill harmful bacteria, including strains resistant to traditional antibiotics, like MRSA.
In our study, we used a mouse model to simulate wound infections. We placed the selenium-coated bandages on wounds and introduced bacteria directly into the area underneath the bandages. After five days, we examined the wounds and the bandages for signs of bacterial growth.
Remarkably, we observed that the bandages effectively protected the wounds, showing no bacterial presence after the five days of monitoring. This suggests that selenium remains effective even after washing, potentially offering a new approach to managing infections in medical settings.
In our study, we used a mouse model to simulate wound infections. We placed the selenium-coated bandages on wounds and introduced bacteria directly into the area underneath the bandages. After five days, we examined the wounds and the bandages for signs of bacterial growth.
Remarkably, we observed that the bandages effectively protected the wounds, showing no bacterial presence after the five days of monitoring. This suggests that selenium remains effective even after washing, potentially offering a new approach to managing infections in medical settings.
8
Control over sinus infections
Most Useful Review
After major surgery and several weeks of continuous viral infections, I sought help from Rm-10 and monolaurin. After taking them continuously, I have since had no illness for nine months! I also found relief from chronic sinus infections, which are typically bacterial. When I sense one coming, I increase my dosage, and within days, I’m symptom-free again. I’m incredibly grateful for these products that have restored my health!
Breast Cancer
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.9
USERS' SCORE
Good
Based on 1 Review
8.5
9
Selenium compounds may fight breast cancer
Di- and Triselenoesters-Promising Drug Candidates for the Future Therapy of Triple-Negative Breast Cancer.
Most Relevant Research
We set out to explore the effects of selenium-containing compounds on breast cancer cells, particularly focusing on their potential as treatments. Our research involved testing several novel selenoesters on two breast cancer cell lines, MCF-7 and MDA-MB-231, to understand how these compounds can impact cell growth and survival.
What we found was quite promising. The selenoesters showed significant cytotoxic effects, meaning they can kill cancer cells effectively, even at very low doses. We observed that these compounds triggered important processes that lead to cell death, specifically by activating pathways that make cells undergo apoptosis, or programmed cell death.
The mechanisms at play include both the extrinsic and intrinsic apoptosis pathways, which means they are working from multiple angles to combat cancer. Additionally, these compounds also activate autophagy, a process that helps clear out damaged cells and contributes to the overall effectiveness of the treatment.
In summary, our findings suggest that these selenium-based compounds could be valuable candidates for future breast cancer therapies, worth considering in the ongoing fight against this disease.
What we found was quite promising. The selenoesters showed significant cytotoxic effects, meaning they can kill cancer cells effectively, even at very low doses. We observed that these compounds triggered important processes that lead to cell death, specifically by activating pathways that make cells undergo apoptosis, or programmed cell death.
The mechanisms at play include both the extrinsic and intrinsic apoptosis pathways, which means they are working from multiple angles to combat cancer. Additionally, these compounds also activate autophagy, a process that helps clear out damaged cells and contributes to the overall effectiveness of the treatment.
In summary, our findings suggest that these selenium-based compounds could be valuable candidates for future breast cancer therapies, worth considering in the ongoing fight against this disease.
8
Boost immune system
Most Useful Review
RM-10 is invaluable for those with serious health issues like cancer or MS. For someone with stage 3 or 4 breast cancer, I recommend taking 10 to 20 pills three times daily to bolster the immune system against cancer and chemotherapy. Following an alkaline diet and consuming RM-10, I am now five years in remission. It’s crucial to stay healthy with the right combination of diet, RM-10, and probiotics.
Bronchitis
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
9
Significant improvement
Most Useful Review
My rheumatoid arthritis count dramatically decreased after I changed my diet and sought herbal remedies. Although I still experience colds or allergies, I’ve managed to avoid the recurring bronchitis that plagued me every winter for years. Now, it's been two years since I’ve experienced anything close to that. If I begin to feel unwell, I increase my herbal intake and typically recover swiftly, which is a remarkable turnaround for me.
Lung Cancer
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.5
9
Maitake mushroom aids lung cancer defense
Inhibitory effect of MD-Fraction on tumor metastasis: involvement of NK cell activation and suppression of intercellular adhesion molecule (ICAM)-1 expression in lung vascular endothelial cells.
Most Relevant Research
In exploring the impact of the MD-Fraction extracted from maitake mushrooms on lung cancer metastasis, we conducted experiments using a murine model. Our results showed that administering MD-Fraction just two days before tumor cells were implanted significantly reduced the spread of both colon-26 carcinoma and B16/BL6 melanoma cells to the lungs.
We found that this mushroom extract enhances the production of IL-12 from antigen presenting cells (APCs), which are crucial for triggering immune responses. Treatment with MD-Fraction also activated natural killer (NK) cells, leading to increased tumor cell killing capacity. Notably, when we depleted the NK cells using a specific antibody, the anti-metastatic effects of MD-Fraction disappeared, further confirming the importance of NK cell activity in this process.
Additionally, in our ex vivo tests, we discovered that MD-Fraction inhibited the adhesion of melanoma cells to activated lung vascular endothelial cells. This effect was also mirrored by using an anti-intercellular adhesion molecule (ICAM)-1 antibody, suggesting that MD-Fraction operates by suppressing ICAM-1 and thereby reducing the ability of cancer cells to latch onto the blood vessel walls.
Overall, our findings indicate that MD-Fraction from maitake mushrooms shows promise in inhibiting lung cancer metastasis, primarily through immune activation and interference with tumor cell adhesion.
We found that this mushroom extract enhances the production of IL-12 from antigen presenting cells (APCs), which are crucial for triggering immune responses. Treatment with MD-Fraction also activated natural killer (NK) cells, leading to increased tumor cell killing capacity. Notably, when we depleted the NK cells using a specific antibody, the anti-metastatic effects of MD-Fraction disappeared, further confirming the importance of NK cell activity in this process.
Additionally, in our ex vivo tests, we discovered that MD-Fraction inhibited the adhesion of melanoma cells to activated lung vascular endothelial cells. This effect was also mirrored by using an anti-intercellular adhesion molecule (ICAM)-1 antibody, suggesting that MD-Fraction operates by suppressing ICAM-1 and thereby reducing the ability of cancer cells to latch onto the blood vessel walls.
Overall, our findings indicate that MD-Fraction from maitake mushrooms shows promise in inhibiting lung cancer metastasis, primarily through immune activation and interference with tumor cell adhesion.
8.8
Reduces cancer risk
Most Useful Review
Essential. Since I began taking this supplement a few years ago, I haven’t had colds or flu. This supplement contains 100 mcg of Selenium per dose. Studies have shown that selenium could reduce the risk of lung cancer significantly and overall cancer deaths, which is indeed promising.
Prostate Cancer
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.5
USERS' SCORE
Good
Based on 1 Review
8.5
8
Selenium nanoparticles show promise
Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells.
Most Relevant Research
We explored the impact of selenium nanoparticles, known for their potential anti-cancer properties, on aggressive prostate cancer cells, specifically the PC-3 line. The study focused on understanding how sub-toxic levels of selenium functionalized nanoparticles affect cell proliferation and their intracellular behavior.
By utilizing advanced imaging techniques and careful cryopreparation, we aimed to preserve the integrity of the cancer cells while analyzing the distribution of these nanoparticles within them. Our findings revealed that nanoparticles coated with bovine serum albumin (BSA) reduced the migration capability of the cancer cells more effectively than those coated with chitosan.
This difference may be attributed to the BSA coating's ability to prevent harmful interactions with the cell membranes, which in turn limits the generation of reactive oxygen species that can damage cells. Most intriguingly, we observed that these selenium nanoparticles localized in both the mitochondria and lysosome-related organelles within the cells. The presence of nanoparticles in the mitochondria might explain the significant reduction in the PC-3 cells' ability to proliferate.
Overall, our investigation highlights the promising role selenium nanoparticles can play in cancer treatment strategies, providing valuable insights for further research into their cytotoxic mechanisms against prostate cancer.
By utilizing advanced imaging techniques and careful cryopreparation, we aimed to preserve the integrity of the cancer cells while analyzing the distribution of these nanoparticles within them. Our findings revealed that nanoparticles coated with bovine serum albumin (BSA) reduced the migration capability of the cancer cells more effectively than those coated with chitosan.
This difference may be attributed to the BSA coating's ability to prevent harmful interactions with the cell membranes, which in turn limits the generation of reactive oxygen species that can damage cells. Most intriguingly, we observed that these selenium nanoparticles localized in both the mitochondria and lysosome-related organelles within the cells. The presence of nanoparticles in the mitochondria might explain the significant reduction in the PC-3 cells' ability to proliferate.
Overall, our investigation highlights the promising role selenium nanoparticles can play in cancer treatment strategies, providing valuable insights for further research into their cytotoxic mechanisms against prostate cancer.
8.8
Cancer reduction
Most Useful Review
Essential. Since I started taking this supplement a few years ago, I no longer contract colds and flu. This supplement contains 100 mcg of Selenium per dosage (2 pills). Selenium could be beneficial, but it’s crucial not to overdose. A study showed that daily 200 micrograms of selenium reduced cancer occurrences by 42% among older participants compared to a placebo. Selenium users also had up to 63% fewer prostate cancers.
Sore Throat
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Boosts immune system
Most Useful Review
will help you get healthy & stay healthy. My immune system is weak. I catch every virus going around. However, if I begin taking this three times a day at the first sign of illness, like a scratchy or mildly sore throat, it helps thwart the virus altogether. Taking it daily boosts my immune system, so I rarely fall ill. I have used this for years to improve my immune health. Although it's pricey, I highly recommend it as it proves worth the investment. I can go to work and spend time with my grown children without constantly being unwell. Being ill can cost me significantly in doctor visits and lost wages. Thus, I find this much more affordable than it first seems. Highly recommend!
Cough
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.4
7.5
Immune system maintained
Most Useful Review
I have been taking six pills daily for the past month before lunch, typically on an empty stomach. They seem to keep my immune system functioning well, as my wife has had a nasty cold for weeks, and I haven't caught it. Despite being surrounded by coughs, I've remained well. I would recommend them.
