Supplement Facts
Serving Size:  2 Capsules
Amount Per Serving
%DV
Mood Probiotic BlendLactobacillus acidophilusLactobacillus plantarumLactobacillus helveticus R0052Lactobacillus paracaseiLactobacillus caseiLactobacillus brevisLactobacillus rhamnosusLactobacillus bulgaricusLactobacillus gasseriLactobacillus salivariusTotal Lacto Cultures (45 Billion CFU)Bifidobacterium lactisBifidobacterium longum R0175Bifidobacterium bifidumBifidobacterium breveBifidobacterium infantisBifidobacterium longumTotal Bifido Cultures (5 Billion CFU)
200 mg
+
Total Probiotic Cultures
50 Billion CFU¹
 
Stress Support BlendOrganic Ashwagandha (root), Blueberry (fruit)
350 mg
+
Organic Prebiotic Fiber BlendOrganic Potato [Resistant Starch] (tuber), Organic Acacia Fiber (A. senegal)
675 mg
+

The product is found useful for the following medical conditions

Headache details

SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.4
USERS' SCORE
Good
Based on 2 Reviews
8.6
We aimed to explore the link between dietary intake of long-chain omega-3 fatty acids, specifically docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and their potential impact on headache prevalence in the U.S. Using data from the National Health and Nutrition Examination Surveys conducted between 1999 and 2004, we looked at a diverse group of over 12,000 adults aged 20 and older.

Through interviews, participants reported experiences of severe headaches or migraines in the past three months. We also measured dietary EPA and DHA from their food intake and assessed levels of C-reactive protein, which is an indicator of inflammation. Our analysis suggested that increased intake of omega-3 fatty acids correlated with a lower prevalence of severe headaches or migraines. Specifically, each log unit increase in EPA was linked to a 6% reduction in the prevalence—while DHA showed a similar reduction.

Interestingly, we found that this effect was more pronounced among non-Mexican Hispanic participants compared to others. Importantly, our results remained robust even after considering inflammation levels. Thus, this study supports the idea that omega-3 fatty acids may be beneficial in helping to prevent or alleviate headaches.
9
Stopped headaches completely
Most Useful Review
5 people found this helpful
These gave me severe headaches. I take probiotics regularly, but after trying these, I kept waking up with a headache. After analysing everything I consumed, I realised these were causing my morning headaches. Upon stopping them, my headaches disappeared.

Cold details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Strengthened immune system
Most Useful Review
5 people found this helpful
Keep up the Immune System. I can't imagine not taking them! As a teacher of young children, I am around numerous colds and other illnesses throughout the year. I used to get sick very easily. My doctor recommended probiotics, and I chose these for their mood component. Since starting them, I haven't been sick once and swear by them for my immune system. I would highly recommend!

Yeast Infection details

SCIENTIFIC SCORE
Moderately Effective
Based on 32 Researches
8.3
USERS' SCORE
Good
Based on 7 Reviews
8.4
We examined the effect of lactic acid bacteria, particularly Lactobacillus gasseri, on the harmful yeast Candida albicans. Our study showed that the metabolites from L. gasseri effectively inhibit the yeast's ability to grow and form biofilms, crucial for its pathogenicity. The research also indicated that these beneficial bacteria can keep C. albicans in a less harmful state by downregulating important genes responsible for its virulence. Overall, L. gasseri appears to be a promising option in the fight against vaginal yeast infections.
8
Effective for yeast infection
Most Useful Review
19 people found this helpful
The effect is very good. I often experience a recurrence of yeast infection, particularly when I exercise in hot, humid conditions, and symptoms such as itching worsen before menstruation. This product, featuring 50 billion lactobacillus strains crafted by doctors, is a bit pricey, but I'm very satisfied with it. I take it first thing in the morning while fasting and would recommend it due to its effectiveness. While Garden of Life products are costly, they prioritise quality and the nutritional composition of their strains. One tablet a day lasts two months, making it affordable when considering the health benefits. I believe 80% of my immunity comes from gut health, and consistent intake is essential for maximising its benefits. The inclusion of prebiotics enhances the absorption of lactic acid bacteria, which is advantageous.

Colitis details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.4
8
Continues to work
Most Useful Review
1 people found this helpful
Suffering from colitis has led me to try numerous probiotics. However, this one has been the best for me! I’ve noticed it’s improved my mood and brain fog, and I hope it continues to serve me well as a lifelong customer.

Brain Tumor details

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.3
USERS' SCORE
Good
Based on 5 Reviews
8.3
We explored an innovative approach to treating glioblastoma, the most common malignant brain tumor, by utilizing docosahexaenoic acid (DHA) liposomes. These liposomes were created using a microfluidic system that allowed for fine-tuning various properties, which could enhance their effectiveness in targeting tumor cells.

Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.

Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
7.5
Enhanced relaxation
Most Useful Review
2 people found this helpful
Wonderful probiotic! This excellent product significantly enhances the body and helps one feel more relaxed. It effectively regulates the entire brain.

Chronic Fatigue Syndrome details

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7
USERS' SCORE
Good
Based on 3 Reviews
8.3
We explored the effects of Lactobacillus acidophilus, both free and in floating beads, as a possible treatment for chronic fatigue syndrome in a rat model. The study involved inducing fatigue through a forced swim test and then administering the probiotics over the last week of the experiment.

Remarkably, we found that both forms of Lactobacillus led to significant reductions in fatigue-like behaviors and improved biomarkers associated with stress. This indicates that lactobacilli may serve as a beneficial option for alleviating symptoms of chronic fatigue syndrome.
7.5
Symptom relief
Most Useful Review
6 people found this helpful
The quality of this product is impressive, containing billions of natural probiotics. It has greatly improved my digestion, and I recommend taking it with a natural prebiotic. I consume two capsules daily for two weeks before my period, which has notably alleviated the symptoms of chronic fatigue syndrome. I wholeheartedly recommend this to all women!

Depression details

SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.2
USERS' SCORE
Good
Based on 14 Reviews
8.3
We conducted a study to find out whether docosahexaenoic acid (DHA), a type of omega-3 fatty acid, could effectively help those dealing with major depressive disorder (MDD). Over the course of 12 weeks, 60 participants were involved in a double-blind, placebo-controlled trial. They were divided into two groups: one received 3.2 grams of DHA daily, while the other group was given an equivalent amount of soybean oil as a placebo.

Throughout the study, we measured depression levels using the Hamilton Rating Scale for Depression (HRSD). Our results were intriguing—those taking the DHA showed significant improvements in their depression scores compared to the placebo group by weeks 4, 6, 8, and 12. While we noted that 26.7% of participants receiving DHA achieved remission by week 12, this was not statistically significant in comparison to the placebo group.

Overall, our findings support the idea that DHA may serve as a promising alternative treatment for individuals suffering from MDD. Although the results are encouraging, we recognize the need for further research to confirm these benefits conclusively.
7.5
Effective for depression
Most Useful Review
23 people found this helpful
I am satisfied with these probiotics, which support emotional well-being. They contain strains that help calm feelings, relieve stress, and promote relaxation. I previously took a different brand last winter but found similar strains. This product particularly enhanced my mood, which was crucial given my seasonal depression. I noticed substantial improvement in my feelings, likely due to the probiotic strains used, rather than just an ingredient like Ash, which I consumed separately. Unlike my previous product, this one doesn't compromise mood support. It even contains acacia fibre, beneficial for gut health, and I plan to repurchase.

Rash details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
7.5
Cleaner skin
Most Useful Review
1 people found this helpful
I have faith in this brand as all their supplements are of superb quality. The probiotics work excellently; I noticed an improvement in bowel function after the first capsule. With extended use, I've seen that my skin looks clearer, and there are significantly fewer rashes, not just on my face but across my body.

Swollen Lymph Nodes details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
7.5
Quick relief found
Most Useful Review
19 people found this helpful
The Best Of What She Brala. I tried around five types of bacteria from this site and even from local pharmacies, and this is by far the best. After consuming grapes, the swelling would arise, but upon taking the capsule, everything subsides within an hour. I am astounded by how many people mix bacteria into milk or kefir! It’s a unique method that requires no refrigeration. They are simply extraordinary! I highly recommend trying them—you won't be disappointed.

Candidiasis details

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 6 Reviews
8.2
We set out to explore how lactobacillus acidophilus, specifically strain B-2178, impacts vulvovaginal candidiasis (VVC) in female rats. By dividing our study subjects into five groups, we included controls and examined the effects of different treatments.

In particular, we analyzed the immune response of the vaginal tissue after intravaginal inoculation to establish VVC. The rats treated with strain B-2178 showed a promising ability to maintain an immune-tolerant state in the vaginal epithelium. Through this action, it seemed capable of reducing uncontrolled inflammation, which is often a challenge during candidiasis.

Although our findings suggest that B-2178 may be beneficial in treating VVC, it's important to note that the overall focus was broader and did not isolate lactobacillus acidophilus alone. This makes it difficult to pinpoint the specific advantages of this particular strain compared to others.

Ultimately, it appears that while B-2178 exhibits potential, more targeted research is required to evaluate its effectiveness in isolating and addressing candidiasis comprehensively.
9
Highly effective choice
Most Useful Review
19 people found this helpful
The effect is very good. I often suffer from recurrent yeast infections due to frequent exercise in a hot and humid environment, which worsens symptoms like itching, especially before menstruation. This product is excellent, offering 50 billion lactic acid bacteria formulated by professionals, and although a bit pricey, I am very satisfied. I take it as soon as I wake up, and recommend it to others due to its efficacy. Even though Garden of Life products are costly, they are dedicated to quality and nutritional composition. If taken daily, one bottle lasts two months, making it affordable for maintaining health. Since a large part of immunity stems from gut health, consistent intake of lactic acid bacteria is beneficial, especially as this product includes prebiotics that aid absorption.

High Cholesterol details

SCIENTIFIC SCORE
Moderately Effective
Based on 29 Researches
8.1
USERS' SCORE
Good
Based on 3 Reviews
8.2
We explored how Lactobacillus rhamnosus BFE5264 affects cholesterol levels using a mouse model on a high-cholesterol diet. This study revealed that this strain significantly reduced serum cholesterol levels while also altering the gut microbiome and increasing beneficial short-chain fatty acids. The findings suggest that L. rhamnosus could regulate cholesterol metabolism in the liver, showing effects similar to those of statin medications. These results highlight the potential of probiotics as a novel approach for managing cholesterol levels.
9
Resolved gut issues
Most Useful Review
This is a great product; my gut issues were resolved after about two weeks of use. I would highly recommend these probiotics.

Diarrhea details

SCIENTIFIC SCORE
Moderately Effective
Based on 84 Researches
8
USERS' SCORE
Good
Based on 6 Reviews
8.1
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.

Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.

Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.

This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
10
Diarrhoea relief
Most Useful Review
35 people found this helpful
This product has been life-changing! After 9 years of chronic diarrhoea and long-term depression, within 2 weeks of taking this supplement, my diarrhoea was gone, and my mood improved significantly.

Indigestion details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 7 Reviews
8.1
This study looked into how a specific synbiotic product, which includes Lactobacillus acidophilus along with other probiotics and fructooligosaccharides, affects digestive health among healthy adults. In a randomized, double-blind, placebo-controlled design, we monitored 36 participants—20 women and 16 men aged between 25 and 45 years—over six weeks.

Participants received either the synbiotic supplement or a placebo, taking three tablets daily. We gathered information on gastrointestinal symptoms and bowel habits through a self-administered questionnaire, focusing especially on those who experienced digestive disturbances like mild dyspepsia or bloating.

The results were promising; those who took the synbiotic product reported significant improvements in their overall gastrointestinal well-being and bowel movements. Interestingly, we also noted a reduction in a specific immune marker, L-selectin, in the synbiotic group, which could indicate a favorable shift in their immune profile. However, while the improvements in gut health were noteworthy, none of the other immunological parameters were significantly altered.

In summary, this study suggests that including Lactobacillus acidophilus as part of a synbiotic supplement can lead to better digestive comfort and may influence immune-related markers positively. However, pinpointing the exact effect of this specific strain on indigestion alone is challenging, given the multi-strain nature of the synbiotic treatment.
9
Calming effect
Most Useful Review
2 people found this helpful
This product has really helped with my husband's indigestion problem. After taking it for over three weeks myself, I've realised I am much calmer now.

Constipation details

SCIENTIFIC SCORE
Possibly Effective
Based on 72 Researches
7.7
USERS' SCORE
Good
Based on 28 Reviews
8
We examined the effects of Lacticaseibacillus rhamnosus IDCC 3201 on patients suffering from irritable bowel syndrome with constipation (IBS-C). In a robust study involving 30 participants, we used a randomized, double-blind, placebo-controlled design.

After eight weeks of treatment, the probiotic group reported significant improvements in bowel activities and discomfort linked to constipation. Notably, symptoms like abdominal bloating also improved.

Our findings suggest that this probiotic might help enhance gut health by promoting beneficial microbes and their metabolites.
10
Best probiotic ever
Most Useful Review
6 people found this helpful
This is the best probiotic for my chronic constipation; I've tried everything over the counter including laxatives and enemas. Alongside flaxseed and "baby plum organics" pouches daily, this probiotic is more effective than any I've taken. It also helps improve my mood while I transition to supplements.

Autoimmune Disorder details

SCIENTIFIC SCORE
Possibly Effective
Based on 55 Researches
7.9
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.9
We explored the effects of probiotic LC-STH-13 on systemic lupus erythematosus (SLE) in MRL/lpr mice. Our study demonstrated that LC-STH-13 significantly decreased harmful autoantibodies and rebalanced specific immune cells.

We also observed reduced immune cell infiltration in kidney tissue, indicating less inflammation. Furthermore, the probiotic helped restore healthy gut microbiota which gets disrupted by SLE. These findings suggest that LC-STH-13 may offer a novel way to manage lupus by targeting both immune regulation and gut health.
9
Increased immunity
Most Useful Review
31 people found this helpful
If it had more than five stars, I would award it. My husband has greatly benefited in terms of immunity. He suffered from weather changes and often fell ill, but after consistently taking this, he has improved significantly. This is his fourth reorder due to the substantial benefits he's experienced, with God's grace. If you appreciate my review, please like 🤍

Back Pain details

SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.9
We aimed to find out how docosahexaenoic acid (DHA), a key omega-3 fatty acid, could affect intervertebral disc (IVD) degeneration, a common cause of lower back pain. In our study, we used a group of 12 rats, all of whom underwent a procedure to induce disc degeneration.

After the injury, half of the rats were given a daily supplement of omega-3 fatty acids, while the other half received only a sugar solution as control. Over the course of the study, we measured various outcomes related to inflammation and disc health.

We observed that the omega-3 group showed a significant reduction in blood markers associated with inflammation. Additionally, the results indicated that those receiving DHA were less affected by disc dehydration, and the tissue damage due to the induced injury was noticeably less severe in this group.

Overall, this suggests that increasing our intake of omega-3 fatty acids, like DHA, may offer protective effects against the degeneration of intervertebral discs and could potentially ease back pain related to this condition.
9
Significant emotional stability
Most Useful Review
9 people found this helpful
After a month, I returned for my second bottle. This product has helped me more than antidepressants ever did. The connection between gut health and mental health is real, and I'm incredibly grateful for it! I feel stable emotionally, without extreme lows, and have even lost a few pounds. This experience has been life-changing, and I hope it helps someone else, too.

Anxiety details

SCIENTIFIC SCORE
Possibly Effective
Based on 52 Researches
7.4
USERS' SCORE
Moderately Good
Based on 24 Reviews
7.8
We explored how the treatment with JB-1—a type of probiotic bacteria—affects anxiety during chronic stress in rats. In our study, half of the twenty rats received JB-1 while the other half got a placebo over eight weeks of stress exposure.

The results were telling! Rats on JB-1 showed less anxiety and were more willing to explore their environment compared to the placebo group, which largely avoided exploration. Additionally, measurements of brain metabolites indicated that JB-1 helped maintain stability in brain chemistry, even in stressful conditions.

This suggests that lactobacillus rhamnosus might play a beneficial role in reducing anxiety during prolonged stress.
7.5
Mood enhancement
Most Useful Review
33 people found this helpful
After years of taking plexus probio5 and vitalbiome, I realised I needed a higher dosage. I compared probiotics for similar ingredients and found these at better strengths for less. I've been taking them for months, and they significantly improve my mood and anxiety, making me seem much calmer.

Food Poisoning details

SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.8
USERS' SCORE
Moderately Good
Based on 6 Reviews
7.8
We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.

Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.
7.5
Reduced food worries
Most Useful Review
I absolutely love it! It's helped me enjoy various types of food without worries of discomfort.

Leg Cramps details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.8
9
Helpful for digestion
Most Useful Review
This add-in appears to work well and offers excellent value for money. It has greatly aided my digestion and constipation, acting smoothly without any pain or leg cramps. I can't discern a taste.

Irritable Bowel Syndrome details

SCIENTIFIC SCORE
Possibly Effective
Based on 56 Researches
7.5
USERS' SCORE
Moderately Good
Based on 8 Reviews
7.7
We assessed how Bifidobacterium bifidum MIMBb75 impacts symptoms of irritable bowel syndrome (IBS) in a controlled study of 122 participants.

Over four weeks, those taking MIMBb75 reported significantly reduced IBS symptoms compared to the placebo group.

With many experiencing better pain relief and improved quality of life, these findings suggest that MIMBb75 could be a valuable treatment option for IBS, showing durability with minimal side effects.
7.5
Improved constipation
Most Useful Review
1 people found this helpful
The quality is good, the ingredients are sound, and the quantity is reasonable. After consulting my doctor, I feel it has improved my constipation and bowel movements significantly.

Sleep Apnea details

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 18 Reviews
7.7
We investigated how the omega-3 fatty acid docosahexaenoic acid (DHA) impacts the severity of obstructive sleep apnea (OSA) in 350 patients undergoing sleep studies. Our study aimed to determine if there is a relationship between the levels of DHA in red blood cells (RBC) and the severity of sleep apnea, categorized as none/mild, moderate, or severe based on apnea hypopnea index (AHI) scores.

Our findings revealed that lower levels of DHA are linked to more severe cases of OSA. For each standard deviation increase in DHA, patients were about 50% less likely to be classified in the severe apnea category. Specifically, we noted decreased odds of falling into the severe OSA group when DHA levels were higher, suggesting that DHA may play an important role in the severity of this condition.

These insights imply that maintaining healthy DHA levels could potentially influence OSA severity and could aid in developing treatment strategies. We believe that future research should explore the potential benefits of DHA supplementation for those suffering from sleep apnea.
9
Reduced anxiety episodes
Most Useful Review
6 people found this helpful
My wife, who has progressive vascular dementia, experienced debilitating episodes for a year. After starting her on these mood probiotics, her episodes ceased after a couple of days. She now sleeps better at night, finding peace. We both feel we're resting more effectively, and I've started taking these "magic pills" too.

Insomnia details

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.6
We explored the relationship between plasma metabolites, including docosahexaenoic acid (DHA), and sleep quality using data from a large cohort study. Our investigation focused on participants' experiences with sleep issues such as difficulty falling asleep and snoring.

Through a meticulous analysis, we found that higher levels of DHA, alongside certain cholesterol types, were linked to lower odds of snoring. However, we didn't uncover a direct connection between DHA and improvements in insomnia, specifically when it came to falling asleep or waking up during the night.

This suggests that while DHA may play a role in sleep quality related to snoring, its impact on insomnia isn't clearly established. Our findings indicate that more nuanced studies would be beneficial in determining the precise effects of DHA on sleep disturbances.
10
Significant sleep effect
Most Useful Review
This probiotic helped elderly individuals suffering from insomnia to improve their depression and overall mood significantly. After trying various sleeping pills, I found this product allowed me to sleep soundly for eight hours, which was truly unexpected.

Bloating details

SCIENTIFIC SCORE
Possibly Effective
Based on 41 Researches
7.8
USERS' SCORE
Moderately Good
Based on 29 Reviews
7.2
We conducted a study to see if a fermented dairy product with Bifidobacterium lactis DN-173 010 could help reduce bloating in patients with irritable bowel syndrome (IBS) and constipation. In a controlled trial with 34 participants over four weeks, we found that this probiotic significantly decreased abdominal girth and improved gastrointestinal transit times.

Patients reported feeling less bloated, and symptom severity also decreased. These findings suggest that fostering faster transit times may be an effective method to combat abdominal distension.
9
Removes bloating
Most Useful Review
2 people found this helpful
This product excels in addressing digestion problems, effectively removes bloating, is easily absorbed, and does not lead to constipation. The taste is also acceptable.
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