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Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Calcium (from Fossilized Coral Calcium)
350 mg
27%
Fossilized Coral Calcium
1 g (1,000 mg)
†
The product is found useful for the following medical conditions
Back Pain details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 21 Reviews
8.9
9
Calcium aids in back pain relief
Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation.
Most Relevant Research
We explored the impact of calcium and vitamin D supplementation combined with sling core stabilization training on back pain in a 70-year-old female patient suffering from osteoporosis. The patient engaged in this form of exercise three times a week, focusing on strengthening the deep muscles of her spine.
After a year of dedicated training, not only did her back pain significantly improve, but a follow-up examination also indicated an increase in her bone mineral density. This suggests that the combined approach of exercise and supplementation might promote better bone health and potentially reduce pain.
However, it’s important to note that while we saw positive changes in this case, the specific contributions of calcium alone cannot be clearly identified due to the concurrent treatments involved. Therefore, we recognize that further studies are needed to isolate calcium's effects to conclusively determine its role in managing back pain effectively.
After a year of dedicated training, not only did her back pain significantly improve, but a follow-up examination also indicated an increase in her bone mineral density. This suggests that the combined approach of exercise and supplementation might promote better bone health and potentially reduce pain.
However, it’s important to note that while we saw positive changes in this case, the specific contributions of calcium alone cannot be clearly identified due to the concurrent treatments involved. Therefore, we recognize that further studies are needed to isolate calcium's effects to conclusively determine its role in managing back pain effectively.
9.5
Marked pain reduction
Most Useful Review
I am delighted to share my experience with Now Foods Coral Calcium. Following numerous back surgeries and persistent pain, I decided to try this product. After switching to it, I noticed a substantial reduction in my back pain and other joint pains, nearly becoming pain-free. I believe this product has helped with my pain significantly.
Bone Pain details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 52 Reviews
8.8
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
Most Relevant Research
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
9.5
Significant improvement
Most Useful Review
I purchased this calcium for my mother based on her doctor's recommendation for her musculoskeletal issues and bone pain. There has been a noticeable improvement after using the supplement; her pain has significantly decreased. I'm confident that this product works, but do consult a healthcare professional before starting any new supplement. It's an excellent choice!
Leg Cramps details
SCIENTIFIC SCORE
Questionable
Based on 8 Researches
5.9
USERS' SCORE
Good
Based on 13 Reviews
8.7
9
Calcium dobesilate reduces leg cramps
Calcium dobesilate for chronic venous insufficiency: a systematic review.
Most Relevant Research
We examined the benefits of calcium dobesilate for patients suffering from chronic venous insufficiency (CVI), particularly focusing on how it impacts symptoms like leg cramps. In a systematic evaluation of ten different clinical trials involving 778 patients, we compared the effects of calcium dobesilate to a placebo.
Our analysis found that calcium dobesilate significantly reduced night cramps, helping patients nearly twice as much as those who received a placebo. The number needed to treat for this relief was calculated to be 8, indicating that for every eight patients treated with calcium dobesilate, one experienced noticeable improvement.
Moreover, patients also reported less discomfort, with a number needed to treat of 4 for that symptom. Interestingly, we noted that those with more severe symptoms experienced even greater relief, suggesting that calcium dobesilate is particularly effective for patients with advanced CVI. However, both doses tested—1,000 mg and 1,500 mg—proved equally effective, which is good news as it suggests that a lower dose might suffice.
Additionally, we found that adverse events were not significantly different from the placebo group, indicating a favorable safety profile. While calcium dobesilate shows promise, we acknowledge the need for further studies to solidify these findings and explore its efficacy in various CVI stages.
Our analysis found that calcium dobesilate significantly reduced night cramps, helping patients nearly twice as much as those who received a placebo. The number needed to treat for this relief was calculated to be 8, indicating that for every eight patients treated with calcium dobesilate, one experienced noticeable improvement.
Moreover, patients also reported less discomfort, with a number needed to treat of 4 for that symptom. Interestingly, we noted that those with more severe symptoms experienced even greater relief, suggesting that calcium dobesilate is particularly effective for patients with advanced CVI. However, both doses tested—1,000 mg and 1,500 mg—proved equally effective, which is good news as it suggests that a lower dose might suffice.
Additionally, we found that adverse events were not significantly different from the placebo group, indicating a favorable safety profile. While calcium dobesilate shows promise, we acknowledge the need for further studies to solidify these findings and explore its efficacy in various CVI stages.
10
No more cramps
Most Useful Review
Great supplement. I've been using this for over a year, and I don't have night leg cramps anymore; I take this in the evening.
Blood Clot details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
Calcium type affects clot risk
Thrombotic Complications Associated With Right Atrial Lines in Neonates and Infants Undergoing Cardiac Surgery. Is Calcium Chloride a Culprit?
Most Relevant Research
We explored the impact of different calcium infusions on clotting risks in neonates undergoing cardiac surgery. Our study involved analyzing data from 135 babies who received either calcium chloride or calcium gluconate during their treatment.
The findings highlighted a significant concern: when using calcium chloride, the incidence of thrombotic events was notably higher compared to those treated with calcium gluconate. Specifically, the odds of experiencing a blood clot were over three times greater in patients given calcium chloride.
With an overall thrombus occurrence of 9.9%, we observed that only 4.6% of the group receiving calcium gluconate developed such complications compared to 15% in the calcium chloride group. The evidence suggests that switching from calcium chloride to calcium gluconate could potentially reduce the risk of harmful blood clots in these vulnerable patients.
The findings highlighted a significant concern: when using calcium chloride, the incidence of thrombotic events was notably higher compared to those treated with calcium gluconate. Specifically, the odds of experiencing a blood clot were over three times greater in patients given calcium chloride.
With an overall thrombus occurrence of 9.9%, we observed that only 4.6% of the group receiving calcium gluconate developed such complications compared to 15% in the calcium chloride group. The evidence suggests that switching from calcium chloride to calcium gluconate could potentially reduce the risk of harmful blood clots in these vulnerable patients.
8.8
Absorption improved
Most Useful Review
Works well; it’s organic, so it is easily absorbed into the blood and aids in my osteoporosis. I have used it and will continue to do so. I have had no issues with digesting it.
Bursitis details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 1 Review
8.6
7
Calcium treatment shows no advantage
Rotator Cuff Calcific Tendinopathy: Randomized Comparison of US-guided Percutaneous Treatments by Using One or Two Needles.
Most Relevant Research
We explored the effectiveness of calcium treatment through ultrasonography-guided procedures for calcific tendinopathy and its relationship with bursitis. Our study involved 211 patients who were randomly assigned to either a single-needle or a double-needle irrigation procedure to address painful calcifications. We closely monitored various factors, including the duration of the procedure and the occurrence of post-procedural bursitis.
Overall, we did not find any significant differences between the two approaches when it came to clinical outcomes like pain relief or movement improvement over the course of a year. Interestingly, while we noted that procedure duration varied depending on the type of calcification being treated, neither approach led to a notable difference in the rate of bursitis after the treatments.
Specifically, the incidence of bursitis was observed in 9% of patients who received the single-needle treatment, compared to 3.6% in those who underwent the double-needle method. However, this difference was not statistically significant either, indicating that both techniques seem to perform similarly in terms of side effects.
In conclusion, our findings suggest that calcium treatment, regardless of whether it is performed using one or two needles, does not significantly impact the likelihood of developing bursitis. The effectiveness of the treatment itself appeared comparable, with clinical improvements seen in both groups.
Overall, we did not find any significant differences between the two approaches when it came to clinical outcomes like pain relief or movement improvement over the course of a year. Interestingly, while we noted that procedure duration varied depending on the type of calcification being treated, neither approach led to a notable difference in the rate of bursitis after the treatments.
Specifically, the incidence of bursitis was observed in 9% of patients who received the single-needle treatment, compared to 3.6% in those who underwent the double-needle method. However, this difference was not statistically significant either, indicating that both techniques seem to perform similarly in terms of side effects.
In conclusion, our findings suggest that calcium treatment, regardless of whether it is performed using one or two needles, does not significantly impact the likelihood of developing bursitis. The effectiveness of the treatment itself appeared comparable, with clinical improvements seen in both groups.
9.5
Improved mobility achieved
Most Useful Review
I suffer from shoulder bursitis with limited motion. Coral calcium has greatly alleviated my pain and restored full motion in my left shoulder. I ensure I never run out!
Autoimmune Disorder details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9.5
USERS' SCORE
Good
Based on 5 Reviews
8.5
9.5
Calcium's role in RA treatment
Hydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti-Inflammation and Osteogenesis.
Most Relevant Research
We investigated how calcium, specifically in the form of two-dimensional layered calcium disilicide nanoparticles (CSNs), can play a role in treating rheumatoid arthritis (RA). Unlike typical RA treatments that primarily focus on reducing inflammation, we observed that CSNs have multifunctional properties that can address the inflammatory aspect while also promoting bone health and repair.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
Through a process called hydrolysis, CSNs release several beneficial components, including hydrogen gas, calcium hydroxide, and silica. Each of these components contributes uniquely: hydrogen helps reduce harmful radicals and aids in adjusting surrounding immune cell behavior; calcium hydroxide counters the acidity that can worsen bone loss; and dissolved calcium works with phosphates to encourage bone formation.
We found that the application of CSNs had promising results in tests conducted on both mouse and rabbit models of arthritis. This approach not only targets inflammation but also fosters a healthier bone environment, showing potential as a strong therapeutic option for those living with RA. With high biocompatibility and prospects for clinical transformation, this research suggests a new direction in handling autoimmune disorders using calcium-based therapies.
9.5
Mother feels good
Most Useful Review
I ordered this supplement for my mother, having taken it before. Both my and her experience has been very positive. I’m now on my second order, and my mother feels great, indicating a nice improvement.
Cancer details
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 1 Review
8.5
7
Calcium treatment impacts cancer viability
Investigation of the Bystander Effect on Cell Viability After Application of Combined Electroporation-Based Methods.
Most Relevant Research
We investigated how calcium treatment, in conjunction with various electroporation methods, affects cancer cell viability. In our study, we used 4T1 breast cancer cells and applied different forms of electroporation, such as reversible and irreversible treatments along with calcium electroporation. We were particularly interested in the bystander effect, where treated cells might affect untreated nearby cells.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
By transferring conditioned media from the treated to untreated cells, we observed significant impacts on cell viability. The results showed that after applying calcium electroporation and bleomycin treatments, colony formation plummeted to nearly zero, and metabolic activity dipped as low as 11.62%. Additionally, other assessments, including flow cytometry, confirmed a drastic decrease in cell viability in the presence of calcium therapy.
While the study highlighted calcium’s role in enhancing the effects of electroporation, the combined treatments reduced the overall viability of surrounding cells markedly. We also noticed a delay in wound healing with conditioned media, indicating that calcium treatment could significantly impact not just treated but also neighboring cancer cells. Overall, calcium's combined effects were powerful, emphasizing its utility in cancer treatment strategies.
8
Prevents cancer
Most Useful Review
Coral calcium relaxes veins and assists in controlling or preventing cancer.
Migraine details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Safe calcium supplements
Most Useful Review
NOW is the best company. I found issues with coral calcium supplements having heavy metals, but NOW tests their products for safety. Most calcium supplements trigger migraines for me, but I’m pleased to say Coral Calcium does not.
Osteoporosis details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7
USERS' SCORE
Good
Based on 25 Reviews
8.4
9
Calcium complex enhances bone health
A calcium-loaded complex based on Antarctic krill protein and supplemented with pectin promotes calcium absorption and bone health.
Most Relevant Research
Our research explored the effects of a new calcium-loaded complex, made from Antarctic krill protein and enriched with pectin, on calcium absorption and bone health in mice with calcium deficiency. We created a model that simulated calcium deficiency, which is a significant concern as it can contribute to osteoporosis.
We observed that chronic calcium deprivation led to decreased calcium absorption and deterioration of bone structure. However, the P + Ca + HMP complex significantly improved calcium retention and increased the strength of the femur, indicating a positive impact on bone health.
Additionally, this complex improved the structure of the trabecular network, which is essential for maintaining strong bones. The presence of beneficial bacteria in the gut also rose after the intervention, and these were linked to better calcium absorption and bone synthesis. Overall, these findings point to the potential of the P + Ca + HMP complex as an effective calcium supplement that could help prevent calcium deficiency and thus support bone health.
We observed that chronic calcium deprivation led to decreased calcium absorption and deterioration of bone structure. However, the P + Ca + HMP complex significantly improved calcium retention and increased the strength of the femur, indicating a positive impact on bone health.
Additionally, this complex improved the structure of the trabecular network, which is essential for maintaining strong bones. The presence of beneficial bacteria in the gut also rose after the intervention, and these were linked to better calcium absorption and bone synthesis. Overall, these findings point to the potential of the P + Ca + HMP complex as an effective calcium supplement that could help prevent calcium deficiency and thus support bone health.
9.5
Helped recovery
Most Useful Review
Recommended due to my mother-in-law's hip fracture. Since using this coral calcium, her osteoporosis improved significantly alongside her recovery. I also benefit from it for allergies and eczema.
