NOW Supplements Vitamin A

von Gerstenbergk L, Büsing M, Seufert RM, Doertenbach J, Hottenrott C. [Lose-dose treatment with vitamin A in prevention of stress ulcer in swine]. Langenbecks Arch Chir. 1976;Suppl:224.

Based on 18 Researches

Vitamin A protects against ulcers

We focused on the protective effects of vitamin A on stress-induced gastric lesions in piglets after experiencing hemorrhagic shock. In our study, piglets were subjected to low blood pressure and then treated with different doses of vitamin A. Remarkably, those receiving vitamin A showed no signs of gastric lesions.

This suggests that vitamin A plays a significant role in safeguarding the gastric lining against stress-related damage during critical conditions.

Overall, our findings highlight the potential benefits of vitamin A in both veterinary and human medicine for ulcer prevention under stress.

Strengthened immunity

Most Useful Review

7 people found this helpful

I ordered vitamin A to enhance my retina. Previously, there was a small spot in the light, but after daily intake, it diminished. My treatment lasted three months, during which I also took vitamin C. My immunity strengthened significantly, and I managed to avoid catching an ulcer during the active virus season. Quality and dosage are advantageous.

Yeast Infection details

164 people found this helpful

Vitamin A protects against flu, colds, respiratory tract infections and prevents infections of the digestive and urinary tracts. The jar size is standard. I adore this brand for its quality and affordability! It also aids with acne, my hair has stopped falling out, and my allergies have vanished. I highly recommend it!

Chronic Cough details

Calming chronic cough

3 people found this helpful

I usually take 25,000 IU of vitamin A for asthma, essential for skin and mucous membranes, but purchased this due to stock issues. It's small and easy to consume, making it ideal for someone like me who takes various supplements. During the cold winter months, I take large amounts (50,000 to 70,000 IU). My husband, who has asthma, took 120,000 IU, which calmed his cough. Vitamin C and high protein are also crucial for allergic conditions like asthma.

Cold Sores details

180 people found this helpful

After taking the vitamins daily, I could finally open my mouth normally after three days, and by a week and a half, I had no trace of the seizures. Now, I take these vitamins during cold weather and spring, and the problem with seizures no longer troubles me. I definitely recommend these vitamins if your doctor prescribes them.

Leg Cramps details

Skin condition improved

My 8-year-old son took Vitamin A capsules for skin issues, as it was falling off. After taking the vitamin, his skin returned to normal balance. 👍

Osteoporosis details

Improved health noted

8 people found this helpful

Vitamins are well absorbed: no allergies, heartburn, or digestive issues. I firmly believe that without vitamin D3, youth and beauty are unattainable. So, I went to the pharmacy and found D3 only sold with calcium, which I didn’t need. I take the capsules as directed, ideally with fatty foods: butter, cheese, or soup works well. After two weeks, my overall health has improved, and the whole family enjoys them. I take three to five capsules daily. My skin feels supple, and my hair shines, showing these vitamins' effects even without tests. My children's academic performance has risen, and they seem more energetic. It’s vital for women to help prevent osteoporosis. I highly recommend these vitamins for anyone.

Psoriasis details

38 people found this helpful

It is very useful for my skin as I have psoriasis. More than two months have passed since starting treatment, and I'm very pleased that my plaques have decreased and itchiness is less frequent. The difference is quite noticeable; I only wish I had taken a photo before, as it was much worse! There is also less skin peeling on my face.

Rosacea details

I take it for rosacea. I suffer from rosacea, and when I don’t use retinol in my regimen, I take this vitamin A every evening at a dosage of 10,000 for three months. My rosacea is in remission. The size of the capsules is perfect; I don’t chew them, so they don’t cause any taste discomfort.

Adrenal Gland Disorder details

Skin condition improved

I need vitamin A for my vision, healing of the intestines, and support for the adrenal glands and thyroid. It’s essential to first have an analysis to determine if this vitamin is needed. After taking vitamin A with other supplements, my daughter's skin condition improved significantly, with dryness disappearing and fewer rashes. The supplement is effective; in three months, the vitamin A levels returned to normal according to tests!

Arthritis details

Vitamin A's potential in arthritis treatment

Based on 8 Researches

McBride DA, Kerr MD, Johnson WT, Nguyen A, Zoccheddu M, et al. Immunomodulatory Microparticles Epigenetically Modulate T Cells and Systemically Ameliorate Autoimmune Arthritis. Adv Sci (Weinh). 2023;10:e2202720. doi:10.1002/advs.202202720

We explored the potential of all-trans retinoic acid (ATRA), a form of vitamin A, in treating autoimmune arthritis. The research focused on how ATRA can help improve the body's immune response while reducing inflammation associated with arthritis.

Through innovative use of biodegradable microparticles, ATRA is released directly in the joints over a sustained period, enhancing the body's immune activity. This unique approach helped transform naïve T cells into protective regulatory T cells, which in turn helped to mitigate inflammatory responses.

Notably, the sustained release of ATRA not only improved joint health but also affected the entire body without leading to widespread immune suppression. In animal models of arthritis, those treated with ATRA showed less joint damage and inflammation compared to untreated counterparts, suggesting a promising avenue for managing this challenging condition.

Overall, these findings illuminate the role of vitamin A in potentially modifying the disease course for those battling autoimmune arthritis, indicating exciting new possibilities for treatment that could offer hope for improved patient outcomes.

Disease progression halted

Most Useful Review

I take this as an adjunct to medication in treating rheumatoid arthritis, and the disease has ceased to progress.

Bloating details

Aloe Vera juice is a wonderful addition to your health! I take 1 tablespoon in a glass of water, preferably on an empty stomach. It clears the body and helps normalise the stomach and intestines. I’ve previously tried a concentrate from Herbalife, but this organic juice is far superior! After using it for 40 days with my husband, we found our intestinal health improved significantly. Bloating and belching vanished, and I no longer felt heaviness in my stomach. My appetite has decreased. Quite pleased with the results!

Bronchitis details

Vitamin A supports immune response

Zhang L, Hou Y, Ma Z, Xie J, Fan J, et al. Effect of oral vitamin A supplementation on host immune response to infectious bronchitis virus infection in specific pathogen-free chicken. Poult Sci. 2023;102:102701. doi:10.1016/j.psj.2023.102701

We conducted a study to investigate how vitamin A supplementation affects the immune response in chickens infected with the infectious bronchitis virus (IBV). In our approach, we used 40 one-day-old specific pathogen-free (SPF) chickens, dividing them into two groups. One group received an oral vitamin A treatment daily, while the other group was given a placebo until they were 21 days old.

Afterward, both groups were infected with a pathogenic strain of IBV. Our findings showed that while vitamin A supplementation didn't significantly alter the disease's clinical course or the chickens' overall growth, it had some notable effects on their immune response. Specifically, we observed increased levels of IBV-specific antibodies and a decrease in viral load in certain tissues among the vitamin A group.

Interestingly, vitamin A appeared to also suppress some immune responses, leading to lower expression levels of certain molecules related to inflammation and immune regulation. While vitamin A helped improve specific aspects of the immune response, it did not completely cure the chickens or prevent infection.

Overall, we can conclude that while vitamin A supplementation can offer some benefits in terms of boosting immunity and managing viral replication, it doesn't drastically change the outcome of IBV infections in chickens.

Vitamin A efficacy

Most Useful Review

Vitamin A is an excellent aid for colds, particularly beneficial for bronchitis! It's a staple in our first aid kit.

Bruise details

Skin condition improved

Effective! Vitamin A was prescribed by the doctor, and although I was initially sceptical, the final results were pleasing! Even those around me noticed the improvement in my skin's condition. The colour brightened, dryness disappeared, and the bruises under my eyes lightened! While everyone has their own reasons for taking vitamin A, I enjoyed an unexpected and stunning result. Highly recommend! Try it and see for yourself!

Chickenpox details

Excellent form of Vitamin A. This isn't the first time I've ordered it; it's convenient with an excellent dosage, and I recommend it to everyone. When my children had chickenpox, I gave them this daily for the quickest healing of all mucous membranes!

Insomnia details

Improved sleep quality

105 people found this helpful

Excellent! This is a fantastic supplement! I previously experienced quite severe insomnia, but after nearly a month of usage, I realised that my sleep had improved. It also provides me with a boost of energy in the morning. It’s amusing how those who don't take it can notice the difference too.

Sleep Apnea details

Vitamin A's impact on OSA

Saruhan E, Sertoglu E, Unal Y, Bek S, Kutlu G. The role of antioxidant vitamins and selenium in patients with obstructive sleep apnea. Sleep Breath. 2021;25:923. doi:10.1007/s11325-020-02207-w

We conducted a case-control study to explore the levels of essential antioxidant nutrients, particularly vitamin A, in patients with obstructive sleep apnea (OSA) who did not have any other health issues. By categorizing our 146 subjects based on their apnea-hypopnea index (AHI) scores, we examined how these nutrient levels compared between those with mild to severe OSA and healthy individuals.

Our findings revealed that patients with OSA showed increased concentrations of vitamin A as part of their antioxidant response. This suggests that vitamin A and selenium may serve as important defenses against the harmful impacts of OSA. The implication of our research highlights that supplementing with antioxidant nutrients could be a beneficial approach to enhance overall health in individuals suffering from sleep apnea.

However, while there is a positive correlation between vitamin A levels and OSA, it is important to note that the isolated effects of vitamin A were not the primary focus of our study. Therefore, more research is needed to fully unravel its specific role in treating or managing sleep apnea.

Energy boost

Most Useful Review

135 people found this helpful

Excellent! I genuinely feel like this product delivers on its promises. I've noticed a surge of energy and improved sleep quality, allowing me to enjoy more restful hours. It has also positively impacted my mood, making it a wonderful addition to my routine.

Swollen Lymph Nodes details

Eyelid swelling decreased

I take vitamin A with other supplements to boost my immune system. I specifically chose Now Foods for their quality and dosage. It effectively alleviated the dryness of my mucosa, and my eyes stopped hurting in poor lighting. My eyelids swell less, and the bags under my eyes have disappeared. I really liked this supplement!

Whooping Cough details

After COVID, my mother suffered from a terrible dry cough for a considerable time, which disappeared almost immediately after starting vitamin A! Nothing else worked! Vitamin A is vital for nourishing lung tissue. Please consult your doctor if you smoke. If this review helps, please click YES. I wish everyone good health!

Abscess details

Abscess lump resolved

My 1.5-year-old daughter had a lump on her gums resembling an abscess rather than teeth. I only had vitamin A available, so I gave her a capsule each morning for four days, and the bump disappeared. Now, a tooth is coming through, which is a remarkable discovery and proof of its antiviral properties.

Angina details

Protective against angina

The antioxidant effect of vitamin A is significant in combating heart and arterial diseases. It provides protection for individuals with angina pectoris and enhances levels of good cholesterol in the blood. Additionally, vitamin A effectively combats viruses and bacteria, strengthens nails, and accelerates wound healing.

Colitis details

Positive effect noted

Great! As vitamin A positively influences the mucous membranes of the body, it significantly aids lung function. Consequently, it is highly beneficial in treating gastrointestinal diseases like ulcers or Colitis.

Floaters details

3 people found this helpful

The symptoms of floaters diminish as you become more aware of them. My husband has noticed the same effect. I’ve recommended it to my brother and friends. The small gel capsules are extremely easy to take, and I appreciate their affordable price.

Frozen Shoulder details

10 people found this helpful

Effective for eyestrain. Dry eye and eyestrain have been alleviated! Dr Fujikawa is administering mechavitamin therapy. I began taking one tablet at night, and by the third day, my dry eyes and stiff shoulders from the eyestrain improved. Concerned about an overdose, I take one tablet every three days at my own discretion.

Menopause details

Amazing! Under trial, this wonderful nutritional supplement for women during menopause.

Pelvic Pain details

Effect of vitamin A on menstrual pain

Based on 2 Researches

Sen LC, Jahan I, Salekin N, Shourove JH, Rahman M, et al. Food craving, vitamin A, and menstrual disorders: A comprehensive study on university female students. PLoS One. 2024;19:e0310995. doi:10.1371/journal.pone.0310995

We explored how dietary habits, specifically vitamin A intake, affect menstrual disorders like dysmenorrhea and irregular menstrual cycles among female university students in Bangladesh.

Our findings suggest that students consuming more vitamin A-rich plant foods are significantly less likely to experience these painful conditions. In fact, those who increased their intake had a 40% lower risk of dysmenorrhea and a 60% lower risk of an irregular menstrual cycle.

We also noticed that high fat and sweet food cravings heightened the likelihood of these issues, prompting us to recommend better dietary choices and regular exercise for improved health.

Abdominal pain lessened

Most Useful Review

9 people found this helpful

I have to say, this improves my gastrointestinal tract and nasal mucous membranes. Especially for my stomach, I experienced significantly reduced abdominal pain. The small grains make it easy for anyone to take.

Pneumonia details

Excellent recovery aid

An excellent vitamin! Prescribed by a pulmonologist after my viral pneumonia, I find that drinking it regularly is essential.

Urinary Tract Infection details

Digestive health improvement

Vitamin A is crucial for forming mucous tissue in the respiratory, gastrointestinal, and urinary systems. My child was given it to enhance the digestive system, and it worked effectively, reducing issues significantly.

Warts details

Vitamin A shows limited wart benefits

Based on 6 Researches

Gross G, Pfister H, Hagedorn M, Stahn R. Effect of oral aromatic retinoid (Ro 10-9359) on human papilloma virus-2-induced common warts. Dermatologica. 1983;166:48.

We explored the impact of the oral aromatic retinoid, Ro 10-9359, on common warts caused by human papilloma virus (HPV) 2 in a patient with chronic lymphatic leukemia.

The treatment led to rapid improvement, with no detectable viral particles or DNA during the therapy. However, the treatment had to stop due to the patient's development of a liposarcoma, leading to a relapse of the warts.

Notably, the same HPV-2 subtype was present before and after the treatment, suggesting limited long-term effectiveness.

Wart disappeared

Most Useful Review

The wart on my neck has vanished. I had several small warts there, which my doctor identified as a senile wart. Since I began taking vitamin A, it has significantly improved.

Anemia details

Mejia LA, Erdman JW. Impact of Vitamin A Deficiency on Iron Metabolism and Anemia: A Historical Perspective and Research Advances. Nutr Rev. 2025;83:577. doi:10.1093/nutrit/nuae183

Based on 7 Researches

Vitamin A's role in anemia

We examined the connection between vitamin A deficiency (VAD) and anemia, particularly how a lack of vitamin A can impact iron metabolism in our bodies. Through reviewing existing research, we discovered that VAD doesn't just lead to general anemia but may cause a specific type known as vitamin A deficiency anemia (VADA).

Our findings reveal that vitamin A plays an essential role in the production of red blood cells. When we lack vitamin A, our bodies struggle to utilize iron effectively. Instead of being available for red blood cell production, iron accumulates in our liver and spleen, leading to reduced levels of circulating iron.

We also saw that inflammation and systemic infections could further exacerbate this issue by triggering the liver to produce more hepcidin, a protein that regulates iron levels. The excess hepcidin can create a situation where there isn’t enough iron for the production of hemoglobin, ultimately causing anemia.

Interestingly, our review highlighted that VADA happens not because of a lack of iron, but due to how iron is managed within the body. By understanding these mechanisms, we can work towards creating better strategies to tackle anemia on a global scale.

Cured my anemia

Most Useful Review

4 people found this helpful

The quality is good, with a high dose of fat-soluble vitamin A, which I administered to my child. When overdosed, it caused a severe headache, but I cured my anemia with vitamin A as it's vital for the assimilation of iron. The child's skin has improved, and it's important for immunity. I recommend it!

Chemotherapy details

6 people found this helpful

My husband purchased vitamin A for me from iHerb. After high-dose chemotherapy, I began experiencing issues with brittle nails. After two weeks of using it, my nails have slowly started to grow back. They previously crumbled painfully. Alongside vitamin D3, Omega 3, and calcium from iHerb, the visible results are encouraging. I recommend it to all my acquaintances and friends, as my nails are now manageable.

Conjunctivitis details

Effective for allergies

After starting this supplement, I no longer experience recurrent allergic conjunctivitis. I feel it effectively protects my mucous membranes, and the capsules are small and easy to swallow.

Constipation details

I have been using this product regularly for several months now. I'm pleased to report that both constipation and hemorrhoids have disappeared, even though alleviating these issues wasn't the primary purpose of this medication.

Heart Attack details

Eliminated heart attacks

2 people found this helpful

Terrible experience; however, I noticed my nails stopped breaking after the first two weeks. My skin and hair showed changes after more than a month. Immunity seems unchanged. I was dealing with heart attacks, which prompted me to purchase Omega 3, and honestly, that issue completely vanished. I took a second pack and don't regret it at all.

Heart Disease details

Rettkowski J, Romero-Mulero MC, Singh I, Wadle C, Wrobel J, et al. Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction: a preclinical study. Nat Cell Biol. 2025;27:591. doi:10.1038/s41556-025-01639-4

Based on 7 Researches

Vitamin A modulates heart repair

We investigated the impact of vitamin A in treating heart disease, specifically after a myocardial infarction (MI). Our study focused on over 150 cardiac surgery patients, with a particular emphasis on the effects of vitamin A on bone marrow stem cells. We discovered that MI led to harmful changes in these stem cells and that vitamin A, specifically its metabolite 4-oxo-retinoic acid, helps reduce inflammation by calming the stem cells. This approach could improve heart function in the long run after an MI.

Relieves heart attacks

Most Useful Review

2 people found this helpful

I found that after taking this vitamin, my nails strengthened and skin improved within weeks. Although I cannot gauge the effects on my immunity, my heart issues have vanished, especially after I began taking Omega 3. After two packs, I have no regrets about my purchase.

Influenza details

I take vitamin A as a doctor recommended, using one tablet for a month. During this period, the condition of my skin, hair, and nails has improved. My eyes feel less strained when using the computer, and I have become more resistant to influenza viruses, enhancing my overall immunity. I highly recommend it!

Kidney Stones details

18 people found this helpful

This supplement aids recovery from long-term loss of appetite! Following my surgery, I lost 8 kg in six months due to a lack of hunger, feeling as if I had a stone lodged in my throat. The hospital's medication proved ineffective. I took a mega dose of vitamin A, which surprisingly relieved my throat discomfort and returned my appetite. I took 100,000 IU, but do so at your own risk, as excessive vitamin A can lead to itchy skin and headaches. I experienced severe itching on my feet from overdoing it. This vitamin truly saved my life, and I will continue to take it appropriately.

Knee Pain details

For just over a month, I have used this vitamin and noticed a significant improvement in my energy levels, concentration, and overall health. I am recovering from a recent knee injury and experiencing sleep difficulties; this supplement has made a notable difference.

Sinusitis details

Reduces nasal dryness

19 people found this helpful

Very useful for sinusitis. It reduces dryness in the nose and aids the mucous membrane in forming and eliminating bacteria. This is particularly beneficial for those experiencing issues with their nasal sinuses and allergic rhinitis, taking a capsule every two days.

Bacterial Infection details

2 people found this helpful

Vitamin A, or retinol, is crucial for various bodily functions including the immune system and eye health. It's particularly vital for pregnant women and helps reduce the risk of bacterial and viral infections. Moreover, it provides antioxidant benefits that preserve overall health and youthfulness, making it essential for maintaining skin vitality too.

Blood Clot details

Eliminated nosebleeds

7 people found this helpful

Very effective in strengthening mucous membranes! Before I began taking this, I frequently had blood in my nose when blowing it and experienced stomach upset after consuming oily foods. I also suffered from a sore throat and struggled to sleep in a dry air-conditioned room due to weak mucous membranes. Discovering this product was a godsend! The aforementioned symptoms vanished completely. I find this product exceptionally effective!

Cardiovascular Disease details

28 people found this helpful

Since I started taking vitamin A, my dry eyes no longer bother me. I previously relied on eye drops, but now I've found relief, disputing previous medical advice regarding my condition.

Cholecystitis details

Vitamin A is crucial for the immune system, good vision, and preventing kidney and gallbladder stones, as well as combating dandruff and dry skin. The small capsule is easy to swallow. My family takes it with vitamin C during dinner. After two weeks, my skin became less dry, and I no longer need lotions. Previously, especially after winter, my skin would crack and flake. I believe this vitamin also benefits my internal organs. We’ll take it for a month before taking a break.

Chronic Fatigue Syndrome details

32 people found this helpful

I started taking Vitamin A for eye health and immunity, and thankfully, I have not encountered any side effects. It significantly helped alleviate eye fatigue from computer use. After a two-month treatment, my skin looked beautiful and clear, which I initially didn't attribute to the vitamin. I wish everyone good health!

Eczema details

Alitretinoin improves eczema treatment

Based on 9 Researches

Kislat A, Olah P, Kuchner M, Gerber PA, Schrader J, et al. The Endogenous Dual Retinoid Receptor Agonist Alitretinoin Exhibits Immunoregulatory Functions on Antigen-Presenting Cells. Int J Mol Sci. 2023;24. doi:10.3390/ijms24119654

We explored the effects of alitretinoin, a form of vitamin A, on chronic hand eczema (CHE). This powerful drug is known to target specific receptors in the skin, offering insights into its method of action. Through our detailed study, we examined skin samples from patients who responded well to alitretinoin treatment.

Our analysis revealed a total of 231 genes that were markedly regulated. We found that alitretinoin primarily impacts keratinocytes, the skin's primary cells, by addressing inflammation and enhancing skin barrier function. This treatment improved the expression of certain protective proteins while fostering the production of hyaluronic acid, a substance that helps hydrate and soothe the skin.

Furthermore, we observed that alitretinoin also affects immune cells, particularly dendritic cells, which play a vital role in our immune response. These cells, when treated with alitretinoin, displayed unique alterations in their appearance and function. They had lower levels of specific markers that typically spur an immune response and stimulated the production of IL-10, a cytokine that promotes immune tolerance. Most impressively, these treated cells were less effective at activating T cells, which are crucial for initiating inflammation.

Our findings indicate that alitretinoin not only treats the visible symptoms of eczema but also helps regulate the immune response, providing a dual approach in the management of chronic hand eczema. Ultimately, these insights show that vitamin A treatment holds significant promise for improving outcomes in eczema patients.

Dryness reduction

Most Useful Review

10 people found this helpful

My wife has eczema and severe dryness in her hands. After using this vitamin A, her condition improved and the dryness disappeared, thank God.

Hypothyroidism details

Vitamin A benefits thyroid function

Based on 12 Researches

Farhangi MA, Keshavarz SA, Eshraghian M, Ostadrahimi A, Saboor-Yaraghi AA. The effect of vitamin A supplementation on thyroid function in premenopausal women. J Am Coll Nutr. 2012;31:268.

We conducted a thorough investigation into how vitamin A supplementation might impact thyroid function, particularly focusing on women who are premenopausal and have varying body weights. Our study was a robust, four-month randomized controlled trial involving 84 healthy women aged 17 to 50. Among them, 56 women were classified as obese, while 28 fell into the nonobese category.

Throughout the study, we administered 25,000 IU of vitamin A or a placebo to the obese participants, while nonobese participants received vitamin A as well. Before and after the supplementation period, we measured key thyroid markers, including thyroid-stimulating hormone (TSH), total thyroxine (T4), total triiodothyronine (T3), and proteins associated with vitamin A transport.

Our findings revealed that vitamin A supplementation significantly reduced TSH concentrations in both the obese and nonobese groups, suggesting it may help mitigate the risk of subclinical hypothyroidism. Interestingly, we also noticed an increase in serum T3 levels among those treated with vitamin A. However, T4 levels decreased across all groups, including those not receiving vitamin A.

Overall, it appears that vitamin A may serve as a beneficial intervention for thyroid function in women, particularly those at risk for hypothyroidism. This research highlights an accessible avenue to better support thyroid health through dietary supplementation.

7.5

Vision improved

Most Useful Review

4 people found this helpful

A good vitamin. I have hypothyroidism, and vitamin A is not absorbed from food. After completing the course, I noticed an improvement in my night vision. For better absorption, it's advisable to consume protein and fat during breakfast alongside zinc. Those who smoke or have recently quit should avoid it for up to three years. Pregnant women should consult a doctor, and the dosage might need to be halved. If you enjoyed the review, please show some love! 💓

Lung Cancer details

Grace VMB, Wilson DD, Anushya R. Regulation of inflammation and COX-2 gene expression in benzo (a) pyrene induced lung carcinogenesis in mice by all trans retinoic acid (ATRA). Life Sci. 2021;285:119967. doi:10.1016/j.lfs.2021.119967

Based on 9 Researches

Vitamin A mitigates lung cancer

We aimed to understand how all-trans retinoic acid (ATRA), a form of vitamin A, influences lung cancer development caused by benzo(a)pyrene (B(a)P) exposure in mice. The study involved a thorough examination of the overall health of the mice, including body and organ weights, blood tests, and tissue analysis for any signs of damage or inflammation.

In our observations, B(a)P significantly harmed the mice, leading to weight loss and increased organ weight, particularly in the liver and lungs. Blood analysis revealed a concerning decrease in healthy blood cells and an increase in inflammatory markers, indicating an unhealthy state. However, we found that when these mice were treated with ATRA, their conditions improved remarkably.

The treated mice regained weight, saw improvements in their blood parameters, and exhibited lower levels of cancer-related inflammation. Notably, the expression of the COX-2 gene—an important player in inflammation and cancer—was dramatically reduced with ATRA treatment in both lung and liver tissues. This suggests that ATRA effectively counteracts the inflammatory effects and may help prevent the initial stages of cancer caused by B(a)P exposure.

Overall, our findings highlight the potential of vitamin A in mitigating some of the risks associated with lung cancer development due to environmental carcinogens, supporting further exploration of its role in cancer prevention.

7.5

Significant Improvements

Most Useful Review

53 people found this helpful

For the eyes, skin, and lungs, vitamin A is excellent when combined with fish oil, especially during and after Covid. Following the optimal dosage of one per day ensures no excess. I've seen clear benefits for my family's health during illness; our sense of smell returned rapidly, and my skin glows without flakiness. I've failed to achieve similar results from pharmacy forms of vitamin A. Always consume with fatty foods and avoid mixing with vitamin D for maximum effect. Thank you for reading!

Premenstrual Syndrome details

After completing a course, I can confidently say my hair loss has significantly reduced, and PMS-related chest pain has vanished. My menstruation is now painless, and my skin has stopped drying out excessively, which has relieved my peeling issues.

Adenoiditis details

40 people found this helpful

Excellent! I previously had a weak nose and throat, and despite various supplements and remedies, I saw little improvement. Thinking I lacked vitamin A for my dry throat, I began taking this supplement. Now, my throat feels moisturised. I also take vitamins C, D, and E alongside it. If you're struggling with an issue like nasopharyngitis, I highly recommend giving it a try.

Autoimmune Disorder details

Vitamin A deficiency worsens lupus nephritis

Abdelhamid L, Alajoleen R, Kingsmore KM, Cabana-Puig X, Lu R, et al. Hypovitaminosis A Drives the Progression of Tubulointerstitial Lupus Nephritis through Potentiating Predisease Cellular Autoreactivity. Immunohorizons. 2023;7:17. doi:10.4049/immunohorizons.2200015

We examined the impact of vitamin A deficiency (VAD) on the progression of lupus nephritis in a mouse model. By inducing VAD during pregnancy or after weaning, we discovered that both methods significantly worsened the condition, leading to higher mortality rates.

Interestingly, restoring vitamin A levels after weaning reduced mortality. This suggests that VAD accelerates lupus nephritis through increased immune cell activation and autoantibody production. However, effects were less pronounced when VAD was introduced post-weaning. Overall, the study highlights the potential dangers of vitamin A deficiency in autoimmune diseases.

Seizures alleviated

Most Useful Review

180 people found this helpful

I took vitamins daily and noticed significant improvement after three days, achieving mostly normal mouth movement. After a week and a half, the seizures disappeared—though results can vary for others. I now take these vitamins in courses at the start of cold weather and in spring, and the issue with seizures no longer bothers me. I highly recommend purchasing these vitamins if prescribed by a doctor; you certainly won't regret it.

Depression details

Stabilising insomnia effects

Antioxidant has a stabilising effect on insomnia, depression, autonomic disorders, and various conditions, such as during menopause or in old age. The ingredients are natural, relieving excess stress, stimulating brain function, improving concentration, and increasing performance while normalising sleep and mood. The capsules are medium-sized. GABA, as a neurotransmitter of the central nervous system, enhances sleep quality, and it is during the night that the highest amount of growth hormone is released. This component mitigates stress factors and promotes significantly deeper and more effective sleep. The dosage is optimal.

Eye Infection details

Since I began taking this, I have stopped suffering from recurrent allergic conjunctivitis. I feel it effectively protects my mucous membranes, and the capsules are small and easy to swallow.

Measles details

Vitamin A ineffective in measles treatment

Based on 4 Researches

Lo Vecchio A, Cambriglia MD, Bruzzese D, Guarino A. Vitamin A in Children Hospitalized for Measles in a High-income Country. Pediatr Infect Dis J. 2021;40:723. doi:10.1097/INF.0000000000003156

We conducted a study to evaluate if vitamin A could improve outcomes for children hospitalized with measles in a high-income country. We followed 108 children at a hospital in Southern Italy, comparing those who received vitamin A to a control group. Unfortunately, we found no meaningful differences in fever duration, hospitalization length, or complication rates between the two groups. Ultimately, our results suggest that vitamin A supplementation does not alter the course of measles in these cases.

Restores mucous membranes

Most Useful Review

3 people found this helpful

The quality of this Vitamin A is excellent; its natural ingredients and small capsule size make it easy for children. They have notably helped us during Measles treatment and in restoring mucous membranes.

Allergies details

Lotfi R. Retinoic Acid (RA): A Critical Immunoregulatory Molecule in Asthma and Allergies. Immun Inflamm Dis. 2024;12:e70051. doi:10.1002/iid3.70051

Based on 11 Researches

Vitamin A and allergy management

Our exploration into the effects of vitamin A, particularly its active form known as retinoic acid, revealed some interesting insights regarding allergies. Vitamin A plays a key role in our immune system by helping to regulate immune responses, which is crucial for managing allergic reactions.

Research indicates that retinoic acid can promote the development of regulatory T cells, which are essential for maintaining balance in our immune system. These T cells help to suppress excessive immune responses that can lead to allergies. Additionally, they assist in managing inflammatory responses, which is particularly important for conditions like asthma and allergic reactions.

Notably, studies have shown that levels of retinoic acid are often lower in individuals suffering from asthma and allergies. Moreover, introducing retinoic acid as a treatment has been found to alleviate symptoms associated with allergies and reduce airway inflammation. This suggests that boosting retinoic acid levels in the body might be a promising therapeutic approach for those dealing with allergic conditions.

Overall, we conclude that vitamin A—through its derivative retinoic acid—holds significant potential for improving allergy management by enhancing immune regulation.

Effective for allergies

Most Useful Review

An invaluable aid for respiratory tract infections, this dosage is sufficient. Vitamin A helps protect against flu, colds, and respiratory infections, and it also works on allergies. I appreciate this brand for its quality at a reasonable price! It has improved my acne, reduced hair loss, and has helped with my allergies. Highly recommend it! Quality is excellent.

Anxiety details

Vitamin A's role in anxiety management

Based on 7 Researches

Lin YL, Wei CW, Lerdall TA, Nhieu J, Wei LN. Crabp1 Modulates HPA Axis Homeostasis and Anxiety-like Behaviors by Altering FKBP5 Expression. Int J Mol Sci. 2021;22. doi:10.3390/ijms222212240

We explored how vitamin A, more specifically its active form retinoic acid (RA), impacts anxiety levels. In this study, researchers discovered that a specific protein, cellular RA binding protein 1 (Crabp1), plays a crucial role in regulating responses to stress. Mice lacking Crabp1 showed significantly lower levels of anxiety and less stress-induced hormone release, indicating that Crabp1 dampens the body's stress response.

By examining the interactions between Crabp1 and another protein called FKBP5, we observed that reducing Crabp1 levels led to decreased FKBP5 expression. This is important because lower FKBP5 levels lessened feedback inhibition in the hypothalamic-pituitary-adrenal (HPA) axis, which in turn helped reduce anxiety-like behaviors. It was noted that stress and RA can actually increase Crabp1 levels, which may heighten FKBP5 expression and possibly raise the risk of anxiety disorders.

Essentially, this study sheds light on the complex relationship between vitamin A, Crabp1, and anxiety, suggesting that while Crabp1 modulates stress responses beneficially, an overabundance can potentially increase anxiety risks.

Natural anti-stress

Most Useful Review

Magnesium helps reduce stress and anxiety, improving sleep quality. It acts as a natural anti-stress component by inhibiting excitation processes in the central nervous system and reducing sensitivity to external stimuli.

Cancer details

Vitamin A aids ovarian cancer treatment

Mei B, Li J, Wang D, Feng L, Huang J, et al. All-trans Retinoic Acid Sensitizes Epithelial Ovarian Cancer to PARP Inhibition after Exposure to Cisplatin. Mol Cancer Ther. 2025;24:453. doi:10.1158/1535-7163.MCT-24-0140

We focused on how all-trans retinoic acid (ATRA), a form of vitamin A, helps combat resistance in epithelial ovarian cancer (EOC) when combined with standard platinum-based chemotherapy, such as cisplatin.

Our findings indicate that ATRA effectively reduced PARP inhibitor resistance in EOC cells, both in lab settings and in animal models.

Additionally, using ATRA along with ongoing treatment improved survival rates in EOC-bearing mice. This suggests that ATRA could be an important part of future therapies for enhancing the effectiveness of existing treatments.

Aids wound healing

Most Useful Review

1 people found this helpful

Vitamin A plays a vital role in maintaining the integrity of mucous membranes and skin. It promotes rapid healing of wounds and prevents keratinisation and death of skin cells. This vitamin is essential for protein synthesis in the body and is particularly effective for eye health, especially night vision. Moreover, it is a powerful antioxidant beneficial in cancer treatment and prevention. It also protects the skin from sun damage, making it advisable to take before beach holidays. It influences progesterone synthesis, impacting reproductive function and libido. Daily intake with food enhances absorption.

Common Cold details

Vitamin A supports airway function recovery

Amaral CT, Pontes NN, Maciel BL, Bezerra HS, Triesta AN, et al. Vitamin A deficiency alters airway resistance in children with acute upper respiratory infection. Pediatr Pulmonol. 2013;48:481. doi:10.1002/ppul.22621

We examined the role of vitamin A in helping children recover from upper respiratory infections.

In our case control study involving children aged 4-6, we found that those with respiratory infections had lower vitamin A levels compared to healthy kids.

Surprisingly, while vitamin A seems to support airway function during recovery, children with wheezing did not show the same benefits.

Overall, vitamin A appears vital for maintaining healthy respiratory function, especially when kids are fighting off infections.

Overall health improved

Most Useful Review

92 people found this helpful

I’m delighted with the benefits I’ve gained from this vitamin. After struggling with a cold and other health issues for a couple of years, I tried numerous supplements without success. However, since taking this vitamin, my energy levels have risen significantly, my mood has improved, and my overall health has transformed dramatically.

Food Poisoning details

Quick recovery observed

53 people found this helpful

Essential for the eyes, skin, and lungs during and after Covid. This vitamin A, combined with fish oil, is excellent! Dosage is optimal at one per day without risk of overabundance. Our family took it at the first sign of illness, and we recovered swiftly, with no lingering symptoms. My skin's glow improved, and I experienced no dryness that previously troubled me. I only trust this brand now!

Athlete’s Foot details

Athlete’s foot cleared

3 people found this helpful

The effect was outstanding; the athlete’s foot-like peeling on my feet has been resolved, and the dry feeling in my throat has disappeared. I can't let go of this product.

Back Pain details

14 people found this helpful

My husband had acne all over his back, and while Roaccutane was initially prescribed, it became too expensive. We opted for vitamin A, which was surprisingly affordable. After just two months of taking it, his acne disappeared completely, leaving us both astonished and pleased.

Blurred Vision details

Vitamin A treatment improves blurred vision

Based on 6 Researches

Yamada F, Kato K, Nagashima R, Yonekawa Y, Kashima Y, et al. Case of persistent corneal epithelial damage after cataract surgery leading to diagnosis of vitamin A deficiency. Doc Ophthalmol. 2024;148:121. doi:10.1007/s10633-023-09963-6

We investigated a case of persistent blurred vision following cataract surgery, leading to the discovery of vitamin A deficiency in a 74-year-old man. Using advanced tests like full-field electroretinograms and optical coherence tomography, we noted significant retinal changes and low vitamin A levels.

After administering vitamin A supplements for three months, we saw remarkable improvement in his vision and retinal health. This highlights the importance of diagnosing vitamin A deficiency, especially in patients showing persistent vision problems post-surgery.

Maintains vision quality

Most Useful Review

253 people found this helpful

A highly beneficial supplement for maintaining good vision. It aids in reducing eye strain and restoring visual acuity effectively.

Bone Pain details

Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102:556. doi:10.1136/archdischild-2016-310631

Based on 2 Researches

High vitamin A causes bone pain

We examined a case of a 4-year-old boy who experienced severe bone pain and related symptoms after taking high doses of vitamin A for three months. Despite typical liver-related complications usually associated with vitamin A toxicity, he presented with significant musculoskeletal issues and skin changes. Following the discontinuation of vitamin A, the boy showed a remarkable recovery within two months. This case highlights that excessive vitamin A intake can lead to serious bone pain and other health problems, though he did not develop liver disease as expected.

Alleviates throat pain

Most Useful Review

7 people found this helpful

When experiencing throat discomfort, I take 5 tablets of Vitamin A at once. After this, there is no throat pain the following day. Increasing the dosage is key when any discomfort arises; hence, I recommend it if you're suffering from throat pain.

Acne details

Algarin YA, Pulumati A, Jaalouk D, Tan J, Nouri K. The role of vitamins and nutrients in rosacea. Arch Dermatol Res. 2024;316:142. doi:10.1007/s00403-024-02895-4

Vitamin A's effectiveness in acne

We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.

Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.

Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.

Fights acne

Most Useful Review

214 people found this helpful

Excellent! A beneficial vitamin for aging, dry skin, and combating acne.

Acne details

Algarin YA, Pulumati A, Jaalouk D, Tan J, Nouri K. The role of vitamins and nutrients in rosacea. Arch Dermatol Res. 2024;316:142. doi:10.1007/s00403-024-02895-4

Vitamin A's effectiveness in acne

Fights acne

Most Useful Review

214 people found this helpful

Excellent! A beneficial vitamin for aging, dry skin, and combating acne.

High Cholesterol details

Vitamin A reduces cholesterol plaques

Based on 5 Researches

Zarei L, Bahrami M, Farhad N, Froushani SMA, Abbasi A. All-trans retinoic acid effectively reduces atheroma plaque size in a rabbit model of high-fat-induced atherosclerosis. Adv Clin Exp Med. 2018;27:1631. doi:10.17219/acem/74552

We explored the effects of all-trans retinoic acid (atRA) on atherosclerosis in rabbits fed a high-fat diet. In an experiment where rabbits were divided into groups, some received atRA while others received atorvastatin or both.

We found that atRA effectively reduced plaque size, comparable to atorvastatin, and their combination was even more effective. Additionally, atRA improved the serum lipid profile, suggesting it could be a valuable tool in managing cholesterol levels.

Health improvements

Most Useful Review

90 people found this helpful

Excellent! After taking this vitamin for a month before my doctor’s checkup, she was amazed at my health improvements—my cholesterol levels, blood pressure, and energy levels are all normal now. I feel significantly more energised!

Liver Disease details

Boosted skin vitality

6 people found this helpful

This vitamin remarkably aids liver health, resulting in youthful, smooth skin. I noticed changes within a week and a half after starting. For better absorption, it's ideal to take vitamin A with a meal containing healthy fats. Here's to health and beauty!

Diarrhea details

Vitamin A reduces diarrhea risk

Ali HA, Nuh AM, Abdi HA, Muse AH. Multilevel analysis of prevalence and determinants of diarrhea among under-five children in Somalia: insights from the Somalia demographic and health survey 2020. BMC Public Health. 2025;25:202. doi:10.1186/s12889-025-21435-x

We explored the significant health concern of diarrhea among children under five in Somalia, with a particular focus on how vitamin A supplementation influences this issue. The analysis we conducted utilized data from the 2020 Somalia Demographic and Health Survey, which provided insights into various factors affecting child health.

Our findings revealed that children who received vitamin A were less likely to suffer from diarrhea, showcasing the importance of this nutrient in boosting young immune systems. We observed that alongside vitamin A, factors such as household wealth and maternal education also played crucial roles in determining the risk of diarrhea.

It’s clear that enhancing regular vitamin A supplementation could lead to a notable decrease in diarrhea cases among these young children. The study emphasizes the need for targeted public health initiatives to improve access to vitamin A and other health resources, ultimately protecting our vulnerable children from preventable diseases.

Prefer vitamin A

Most Useful Review

This American supplement is good; the pills are small and tasteless. However, daily intake of high doses of ingredients can lead to problems, so adjusting the amount is wise. I find that beta-carotene causes me diarrhea, which is why I prefer vitamin A instead.

Headache details