NOW Supplements Selenium

Selenium acts as a cofactor in iron absorption. A good selenium level is crucial, as it helps form hemoglobin. Low selenium levels reduce red blood cell lifespan from 110-120 days to between 40-60 days, potentially leading to anemia. Additionally, selenium plays an important role alongside iodine; without selenium, even small iodine doses are poorly tolerated. It’s essential for male health, improving potency and sperm quality. Iodine deficiency combined with selenium deficiency can cause autoimmune thyroiditis.

Arteriosclerosis details

Metabolic enhancement

Selenium, packaged well and shipped quickly at a fair price, boasts several benefits. It promotes metabolic health by converting into selenoproteins, resisting free radicals and enhancing circulation. It is crucial for protecting against arteriosclerosis, reducing inflammation, ensuring thyroid function, and maintaining skin health. It also helps prevent osteoporosis and supports immune function. However, be careful not to exceed the recommended dosage!

Athlete’s Foot details

Significant improvement

20 people found this helpful

Every summer, I would suffer from blisters on the soles of my feet and palms, which resembled athlete’s foot. After researching online, I began taking one tablet a day. Within a week, I noticed a significant improvement and was astonished to finally be free from my long-term troubles of 25 years!

Chronic Cough details

Chronic cough improved

Excellent! I took selenium along with Nascent Iodine to manage my low thyroxine level caused by chronic issues, including chronic cough. After several months of using selenium with other supplements, my thyroxine levels improved. I advise caution with dosages and avoiding goitrogenic foods before and after taking supplements. This review reflects my experience, not professional advice.

Depression details

Selenium's potential in depression treatment

Garcia CS, Besckow EM, da Silva Espíndola CN, D'Avila Nunes G, Zuge NP, et al. Antidepressant-Like Effect of a Selenoindolizine in Mice: In Vivo and In Silico Evidence for the Involvement of the Serotonergic 5-HT Receptors. ACS Chem Neurosci. 2022;13:1746. doi:10.1021/acschemneuro.2c00129

This study explored how a selenium-containing compound, SeI, impacts depression-like behavior in mice. During behavioral tests, this compound reduced immobility, signaling an antidepressant-like effect without affecting movement.

Notably, blocking specific serotonin receptors changed the results, indicating the serotonergic system's involvement. With a low potential for side effects, SeI shows promise for developing new treatments for major depressive disorder (MDD).

However, it's important to note this research was conducted in mice, so effects in humans remain unconfirmed.

Significant improvement

Most Useful Review

96 people found this helpful

This product has been a life changer for me. I felt a great deal of fatigue and depression. Now, I've never been in better shape in my life and have lost 14 pounds. I've been eating healthier and exercising more than ever before, and this vitamin has helped me return to my healthiest self without any supplements.

Updated: Apr 2025

Eczema details

Selenium's combined benefits for sheep

Questionable

Based on 4 Researches

Grace ND, Munday R, Thompson AM, Towers NR, O'Donnell K, et al. Evaluation of intraruminal devices for combined facial eczema control and trace element supplementation in sheep. N Z Vet J. 1997;45:236.

We explored the use of intraruminal devices containing zinc oxide, designed to prevent facial eczema in sheep while also addressing trace element deficiencies. Specifically, we looked at how adding selenium and cobalt to these devices might improve the health of pregnant ewes by monitoring changes in blood selenium and serum Vitamin B12 levels.

The devices we tested included 16.4 mg of selenium, in the form of sodium selenate, and 20.4 mg of cobalt, provided as cobalt sulfate. Our findings revealed that these devices were effective in raising and sustaining higher blood selenium levels for at least 84 days, with notable increases in serum Vitamin B12 for up to 42 days.

This dual action means that the devices not only offer protection against facial eczema but also help prevent trace element deficiencies in sheep, demonstrating a valuable approach for improving overall animal health.

Rapid improvement

Most Useful Review

44 people found this helpful

I get eczema on my hands from heavy metals like nuts and cocoa. I had trouble with my hand eczema for more than a month, but after starting selenium, my fingers returned to their original clean state within a few days, much to my family’s surprise! Selenium aids detoxification and the excretion of heavy metals such as mercury, cadmium, lead, and arsenic. It has a strong antioxidant effect that protects blood vessels and skin from oxidative damage. I take 1-2 pills a day and plan to continue.

Updated: Mar 2026

Leg Cramps details

3 people found this helpful

Selenium has been incredibly beneficial for me; it alleviated pain in my small joints, legs, and kidney issues. After taking selenium, I can now walk for several hours without experiencing heaviness in my legs. Previously, after an hour of walking, I urgently needed to find a chair. Additionally, I can work on the computer for extended periods without suffering from tunnel syndrome.

Migraine details

Selenium showed no significant effects

Based on 2 Researches

Balali A, Sadeghi O, Anjom-Shoae J, Rouhani MH, Khorvash F, et al. The effect of selenium supplementation on oxidative stress, clinical symptoms and mental health status in patients with migraine: a study protocol for a double-blinded randomized clinical trial. Trials. 2024;25:209. doi:10.1186/s13063-024-08018-8

We examined a clinical trial that investigates whether selenium supplementation can help alleviate migraine symptoms. In this randomized, double-blinded study, 72 patients were divided into two groups: one received a daily selenium supplement while the other got a placebo, all over 12 weeks.

We tracked headache severity, frequency, and mental health markers like anxiety and depression, alongside measuring oxidative stress biomarkers. Despite the hopes for selenium’s antioxidant benefits, the trial did not find significant improvements in migraine symptoms or related health measures.

Migraine relief achieved

Most Useful Review

Fine! I appreciated Selenium from this company immensely; my family and I enjoy it together. Alongside, we take Omega and D3 with K2, as well as Yodomarin and Aevit from Russian manufacturers. Regarding efficacy, I was utterly exhausted for a long period, lying in bed without the strength or motivation for daily chores. Now, I wake up refreshed and am active throughout the day! After suffering from migraines for the past four years, particularly with weather changes, I found relief once I introduced Selenium and D3K2. I'm also pleased to say hangovers are a thing of the past; I wake up fresher and more cheerful than ever. I highly recommend staying active and healthy!

Updated: Mar 2026

Uterine Fibroids details

Uterine fibroids shrunk

Combined with iodine, it can treat gynaecological diseases. I consume it with iodine and vitamin B complex. The Uterine Fibroids have shrunk, and the price is very reasonable. This combination is beneficial for gynaecological conditions. I suggest reading the book called The Miracle of Iodine.

This is a fantastic supplement for supporting the adrenals and overcoming adrenal gland disorder fatigue.

Adrenal Gland Disorder details

Best! It's easy to consume, and I have ordered it multiple times. Its effectiveness is proven; I have almost forgotten what a sore throat feels like! This is especially significant considering my chronic angina. The quality for the price is excellent!

Angina details

Candidiasis details

Selenium's antifungal potential explored

Based on 9 Researches

de Siqueira VM, da Silva BGM, Passos JCDS, Pinto AP, da Rocha JBT, et al. (MeOPhSe)2, a synthetic organic selenium compound, inhibits virulence factors of Candida krusei: Adherence to cervical epithelial cells and biofilm formation. J Trace Elem Med Biol. 2022;73:127019. doi:10.1016/j.jtemb.2022.127019

We delved into the potential of a synthetic organic selenium compound, known as p,p'-methoxyl-diphenyl diselenide, or (MeOPhSe), to combat candidiasis, particularly focusing on its effects on Candida krusei. This research is important because Candida species can lead to both mild and serious infections, and finding effective treatments is crucial.

Our study demonstrated that (MeOPhSe) is non-toxic to human cells, such as cervical epithelial and fibroblastic cells, and has a notable antifungal effect. We observed that it inhibited the growth of C. krusei in a dose-dependent manner, altering its growth pattern and extending the length of its lag phase. Most significantly, we found that this compound reduced the ability of both C. krusei and C. albicans to adhere to human cells, a critical step in the infection process.

The reductions we measured were substantial: C. krusei adherence dropped by 37.24%, while C. albicans showed a 32.84% reduction, both being statistically significant. Interestingly, both species responded similarly to (MeOPhSe), highlighting its potential as a broad-spectrum antifungal agent against various Candida infections.

Overall, our findings suggest that (MeOPhSe) holds promise as an antifungal treatment targeting the virulence factors of different Candida species, paving the way for new treatment options in battling candidiasis.

7.5

Boosts health significantly

Most Useful Review

1 people found this helpful

I purchased this as an immune booster, but I discovered it offers much more! It reduces cancer risks, enhances brain health, supports thyroid function, acts as a potent antioxidant, and combats heart disease, to name a few benefits. Additionally, it helps address Candidiasis. When I feel under the weather, I take two pills twice daily, but normally, I only need one pill once a day with food. I highly recommend this product at this dosage (100mcg).

Updated: Apr 2025

Adenoiditis details

Throat pressure reduced

10 people found this helpful

I have thyroid gland issues. Selenium has become irreplaceable for me; I feel better with it, and the lump in my throat has vanished. I now approach the TSH test without fear of poor results. I take it for 1-2 months twice a year, one capsule after breakfast. I recommend selenium with kelp and zinc. The quality is remarkable, with no side effects. The large package lasts a year. Wishing everyone good health!

Alzheimer details

Repairs damaged nerves

My physician mentioned that selenium can repair damaged nerves and prevent Alzheimer's. This trace element is incredibly beneficial for overall health.

139 people found this helpful

Anxiety details

I took this for my thyroid, and within a week, I noticed a significant improvement in my mood and disappearance of anxiety.

Low selenium levels slow metabolic processes, leading to excess weight and obesity, particularly among women. Prolonged selenium deficiency increases the risk of heart attack, diabetes, and other serious conditions. A decrease in selenium can also heighten the odds of intrauterine abnormalities and premature birth. It is crucial to include selenium in complex therapies for cancer, as it helps to prevent the growth of pathological tissues and speeds recovery after chemotherapy. Selenium aids in detoxification, regenerating mucous membranes, and normalising pH in the digestive system.

Chemotherapy details

Neck tightness alleviated

Frozen Shoulder details

12 people found this helpful

I bought selenium casually, and it works wonders—it’s now my favourite supplement. For years, I struggled with stiff shoulders and neck that nothing could resolve. When I stop taking it, my neck tightens again, so I believe it is the effect of selenium. I will continue using it.

High Cholesterol details

Selenium supports cholesterol management

Dhingra S, Bansal MP. Modulation of hypercholesterolemia-induced alterations in apolipoprotein B and HMG-CoA reductase expression by selenium supplementation. Chem Biol Interact. 2006;161:49.

We investigated how selenium supplementation affects cholesterol levels and the associated molecular changes. Using Sprague-Dawley male rats, we fed them diets supplemented with selenium alongside high cholesterol for three months.

The results showed that while apolipoprotein B levels rose with the cholesterol diet, supplementing with 1 ppm of selenium significantly reduced these levels. Additionally, the expression of HMG-CoA reductase also decreased with selenium supplementation.

Overall, our findings suggest that selenium could offer a supportive role in managing lipid metabolism and high cholesterol.

Reduces bad cholesterol

Most Useful Review

222 people found this helpful

I started taking this microelement recently, and it's incredibly beneficial. It thins the blood and reduces bad cholesterol levels. Alongside its anti-inflammatory properties, it supports my nervous system and weight control. I take selenium with zinc and quercetin, and this healthy combination has proven effective for both me and my husband.

Updated: Mar 2026

Hypertension details

Essential for recovery

Selenium is necessary for conditions like arrhythmia, coronary heart disease, hypertension, and recovery after myocardial infarction. It helps normalize fat metabolism and cholesterol levels, while also protecting blood vessels and heart muscle from damage, thereby reducing the likelihood of developing hypertension.

I suffered from insomnia, waking at night around 01:30-02:00 and unable to fall back asleep until 5-6. After three months on selenium, I've stopped waking in the night, possibly calming the nervous system.

Insomnia details

130 people found this helpful

Yeast Infection details

I've consistently purchased this yeast-free selenium for over a year. It’s effective for boosting immunity and has been a reliable addition to my health regimen. I recommend it as an essential supplement.

Abscess details

Long-term improvement

21 people found this helpful

Every summer, I suffered from blisters on my feet and palms resembling athlete's foot. After extensive online research, I began taking one tablet of selenium daily, and within a week, I experienced remarkable improvement. I was astonished to be freed from this long-term issue that had plagued me for 25 years!

Cholecystitis details

Positive impact noted

4 people found this helpful

It’s a cool product! It helps maintain iodine balance, which is easy to see through overall well-being. I’ve been drinking less iodine, which is very important for my thyroid issues. After a double fracture, they promised to remove the cast a week early. Additionally, I have vitamin K2 and calcium linked with vitamin D3. I’m grateful to all involved in this fair campaign! Interestingly, I experienced an acute exacerbation of cholecystitis during this time. Thankfully, taking this handful of pills and folic acid has had a positive effect on my body, even in such a critical situation.

Family illness prevention

Cold Sores details

187 people found this helpful

This is an excellent yeast-free selenium supplement at a reasonable price! Our entire family takes it during the cold season and especially now with the ongoing virus outbreaks. We combine it with a complex of other supplements, and everyone is happy with the results. We've experienced no illnesses or complications, and I highly recommend it!

Diabetes details

Selenium aids gestational diabetes management

Based on 21 Researches

Yigit E, Sayar I. Selenium Supplementation and Gestational Diabetes: A Randomised Controlled Trial. J Coll Physicians Surg Pak. 2024;34:561. doi:10.29271/jcpsp.2024.05.561

We explored whether selenium supplementation could improve blood glucose levels in pregnant women with gestational diabetes. In this randomized controlled trial conducted at an Istanbul university, women diagnosed with gestational diabetes received either diet alone or diet plus 200 µg of selenium daily for four weeks.

Findings showed that pregnant women had lower selenium levels compared to healthy counterparts. Those taking selenium experienced a more significant decrease in blood sugar levels than those on diet alone, indicating a beneficial effect of selenium on managing gestational diabetes.

Reduces sugar levels

Most Useful Review

The quality of this selenium supplement is excellent. The ingredients are appropriate and the quantity is adequate. It is a beneficial dietary supplement, particularly for those with diabetes, as it helps to lower blood sugar levels. There is no redundancy in the formulation, and it has been ordered multiple times. The taste is fine, and it encourages the body to absorb it regularly, making it suitable for those suffering from hypothyroidism or high blood sugar.

Updated: Mar 2026

Gastritis details

Eases gastritis attacks

Good selenium! I've finished the first bottle and will definitely purchase more. The tablets are easy to swallow and relatively odourless. I've found that selenium helps prevent GERD and gastritis attacks when following a healthy diet. It’s effective alongside rational nutrition to manage exacerbations due to dietary indiscretions or stress. Take care of yourself!

4 people found this helpful

Knee Pain details

Three years ago, I underwent surgery for cancer and started taking selenium, hoping to prevent recurrence. Remarkably, the persistent eczema inside my knee disappeared quickly. I haven’t undertaken any other treatment, so it seems this was the cause.

Pelvic Pain details

Selenium boosts antioxidant status

Based on 4 Researches

Shevchenko S Y, Kulchavenya E V, Baranchukova A A. [The possibility of correcting oxidative stress in patients with inflammatory type of chronic abacterial prostatitis (chronic pelvic pain syndrome category IIIa)]. Urologiia. 2023.

We sought to understand how a mineral-vitamin complex, specifically Selzinc-plus, may help treat chronic abacterial prostatitis, a condition often linked with pelvic pain. In a study involving 47 men, we divided them into two groups: one received standard therapy, and the other received additional Selzinc-plus for two months.

While standard therapy showed effects, the antioxidant treatment significantly enhanced these benefits on symptoms. Notably, though the overall antioxidant system improved, no significant changes were observed in leukocyte counts. Our findings suggest that this antioxidant approach may offer added relief for those suffering from pelvic pain.

Knee pain alleviated

Most Useful Review

113 people found this helpful

I have been purchasing this for my mother, who suffers greatly from knee pain. When she takes it, she feels as if she "flies." She follows a course of at least three months, followed by a break of one to two months. The capsules are easy to swallow, and there have been no side effects, only positive results with no pain in her legs.

Updated: Mar 2026

Pneumonia details

Visible health benefits

I have been purchasing this product for my father for some time, and I have seen very effective results. His skin condition and overall health stabilised significantly after his battle with pneumonia.

8 people found this helpful

Polycystic Ovary Syndrome details

This is the best find on iHerb for me. A while back, I ordered it and forgot about it until I was sorting through my vitamin jars. After consulting with my endocrine-gynaecologist about my PCOS diagnosis and disrupted cycle (two years without regular periods), I decided to ask my doctor if I could take it. Once given the go-ahead, I started, and a month later, my first menstruation occurred in a long time. I also take iodine in the mornings; it's a great combo, so consult your doctor and try selenium. 🫶

Selenium is crucial for the immune system and has potent antioxidant and anticancer effects. Individuals with Rheumatoid arthritis often experience selenium deficiency, which can affect their immune response. I found that taking selenium alongside vitamin E enhances its benefits. Although the effects might take some time to manifest, ensuring adequate selenium levels is vital for overall health, particularly for the thyroid. It’s also effective in supporting individuals battling metal poisoning and has aided in my overall well-being.

Rheumatoid Arthritis details

Stroke details

Eliminated blind spots

3 people found this helpful

I was told I had a stroke when my left eye would go blind for about 45 seconds every week. After researching that I was lacking iodine and selenium in my diet, I started taking this product once a day for the past two months and have not experienced a single blind spot since.

Asthma details

Selenium intake boosts lung function

Based on 8 Researches

Jiang H, Yang G, Chen J, Yuan S, Wu J, et al. The correlation between selenium intake and lung function in asthmatic people: a cross-sectional study. Front Nutr. 2024;11:1362119. doi:10.3389/fnut.2024.1362119

This study explored how selenium intake relates to lung function in people with asthma. We analyzed data from 4,541 participants in a national survey using various statistical methods. Our findings showed a positive connection between higher selenium intake and better lung function, particularly in forced vital capacity and forced expiratory volume. We noted that to potentially enhance respiratory health, asthma patients could benefit from consuming between 137.65 mcg and 200 mcg of selenium daily, while also being cautious of any adverse effects.

Reduces asthma symptoms

Most Useful Review

I take selenium annually for a month, following my endocrinologist's advice. It's essential to combine it with zinc. Selenium benefits the thyroid by regulating reactive oxygen species, shielding it from antibodies that may cause inflammation. This mineral is powerful in combating oxidative stress, enhancing immune health, supporting the thyroid, and notably reducing asthma symptoms.

Updated: Mar 2026

Autoimmune Disorder details

Selenium aids Graves' orbitopathy treatment

Questionable

Based on 17 Researches

Sharabati I, Qafesha RM, Hindawi MD, Amro S, Ayesh BM. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials. Clin Endocrinol (Oxf). 2024;101:669. doi:10.1111/cen.15128

We explored how selenium supplementation might help individuals suffering from Graves' orbitopathy, an autoimmune disorder linked to thyroid dysfunction. Our approach involved a systematic review and meta-analysis that assessed results from four randomized controlled trials.

The findings revealed that selenium supplementation had a significant positive impact on various aspects of Graves' orbitopathy. Over a period of six months, patients taking selenium showed a notable reduction in clinical activity scores, which reflect the severity of eye symptoms. Furthermore, their quality of life also improved significantly.

We observed improvements not only in the overall quality of life specific to eye conditions, but also in visual and psychological functioning scores. Additionally, selenium appeared to reduce the width of the eyelids, providing further benefits for eye-related symptoms. However, we found no significant changes in other areas, such as eye bulging or muscle movement abilities.

Importantly, selenium supplementation was deemed safe with minor side effects reported, suggesting it could be a viable option for managing Graves' orbitopathy. While our results are promising, we believe further research is needed to thoroughly validate the long-term effectiveness and safety of selenium treatment for this condition.

Significant hair recovery

Most Useful Review

409 people found this helpful

After suffering from covid, my wife was told by a doctor that her hair was beyond saving. After researching and trying various treatments, I decided to give her selenium in a 100mcg capsule, three times a day. Within a month, she noticed significant improvements - her dry, itchy scalp cleared up, and new hair began growing, bringing back her confidence and lifting her mood. I strongly recommend selenium to anyone facing similar issues; it genuinely worked wonders for us.

Updated: Mar 2026

Cardiovascular Disease details

Selenium aids heart recovery post-MI

Based on 8 Researches

Li T, Liu X, Yang B, Wang Z, Chen Y, et al. Selenium-loaded porous silica nanospheres improve cardiac repair after myocardial infarction by enhancing antioxidant activity and mitophagy. Free Radic Biol Med. 2025;232:292. doi:10.1016/j.freeradbiomed.2025.03.004

This study focused on how selenium-loaded porous silica nanospheres (Se@PSN) could help repair the heart following a myocardial infarction (MI). These tiny particles are designed to neutralize harmful molecules called reactive oxygen species, which play a significant role in heart damage during MI.

We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.

7.5

Nutrient absorption

Most Useful Review

112 people found this helpful

Selenium greatly aids in nutrient absorption and is integral to the proper functioning of the cardiovascular system. It has also resulted in maintaining beautiful, healthy hair.

Updated: Mar 2026

Erectile Dysfunction details

Enhanced erectile function

I ordered it for my spouse based on a doctor's recommendation. After three days of use, he noticed an improvement in his overall condition. Drowsiness and apathy disappeared, and morning awakenings have become easier. He has more energy now. The facial rash has cleared up. Additionally, when combined with other supplements, the quality of sperm improved, which is crucial for those planning a pregnancy. His erectile function improved, and sensitivity during intercourse was enhanced, as observed by me.

Hashimoto details

Selenium effective in Hashimoto's treatment

Peng B, Wang W, Gu Q, Wang P, Teng W, et al. Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis. Front Endocrinol (Lausanne). 2024;15:1445878. doi:10.3389/fendo.2024.1445878

We examined the impact of selenium supplements on thyroid autoantibody levels in patients with Hashimoto's thyroiditis.

In our analysis, selenium showed significant effectiveness in lowering both thyroid peroxidase and thyroglobulin autoantibodies compared to placebo.

However, other supplements like Vitamin D and Myo-inositol, including their combinations, did not demonstrate similar benefits over six months.

This suggests that including selenium might be a valuable addition to traditional treatments for individuals managing Hashimoto's.

Normalised thyroid function

Most Useful Review

2 people found this helpful

After my hypothyroidism diagnosis, the doctor advised me to take selenium alongside vitamins. Fortunately, after a month, analysis showed my thyroid levels had returned to normal, even with the presence of antibodies related to Hashimoto's.

Updated: Apr 2025

Multiple Sclerosis details

Wonderful! I spent three months taking this supplement for my multiple sclerosis. The trembling in my hand completely ceased with the addition of selenium. However, I experienced increased fatigue once I stopped taking it, though my strength improved later. While mielin generally worked well, I am still figuring out its interaction with gluten. Melatonin was effective for a while, helping me sleep at night, but eventually, it stopped being effective.

Strengthens skeletal system

Osteoporosis details

I suffer from Osteoporosis, and my rheumatologist recommended this mineral to me. Since using it, I've noticed that my skeletal system has become stronger!

Selenium has been shown to enhance the antioxidant defence, improving skin and hair conditions. It positively impacts various conditions, including hepatitis and pancreatitis, and supports overall health. An adult's daily intake should be 70-100 mcg, with adjustments during pregnancy.

Pancreatitis details

Rash details

I purchased it recently and have already noticed positive changes in my body. My skin has improved, and there are fewer rashes. Additionally, my mood has elevated, and my drowsiness has disappeared. Consistent use is essential for the best results!

Tuberculosis details

Selenium nanoparticles inhibit tuberculosis growth

Based on 12 Researches

Parveen S, Sur T, Sarkar S, Roy R. Antagonist Impact of Selenium-Based Nanoparticles Against Mycobacterium tuberculosis. Appl Biochem Biotechnol. 2023;195:3606. doi:10.1007/s12010-023-04315-1

We assessed the potential of selenium nanoparticles in inhibiting the growth of Mycobacterium tuberculosis, a major global health threat due to rising drug resistance. Our study showed that these nanoparticles can potentially disrupt the bacteria's cell envelope, indicating a novel strategy for treatment. However, despite some promising results, further research is needed to fully establish their effectiveness and practical application in tuberculosis management.

High-quality supplement

Most Useful Review

Selenium aids in preventing poisoning, heart disease, and reducing stroke risks. It helps fight flu and tuberculosis, decreasing mortality rates among HIV patients. The thyroid gland's antioxidant enzyme activity relies on selenium, which is also vital for hormone regulation in body tissues. This supplement is highly effective and of top quality, addressing essential mineral deficiencies.

Updated: Apr 2025

Atrial Flutter details

Selenium is an important trace element that supports multiple bodily functions, particularly for the heart and immunity. It acts as an antioxidant that minimises free radical damage and benefits those with unhealthy habits. By reducing cardiovascular disease risk and aiding in heavy metal removal, it protects against serious heart conditions. In medicine, it is used to treat arrhythmia and prevent oxygen deprivation in heart tissues. Selenium may also enhance cancer patient outcomes by protecting DNA and bolstering defences against cancer cells. I strongly recommend this mineral for overall health.

Hypothyroidism details

Selenium benefits Hashimoto's patients

Based on 17 Researches

Huwiler VV, Maissen-Abgottspon S, Stanga Z, Mühlebach S, Trepp R, et al. Selenium Supplementation in Patients with Hashimoto Thyroiditis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Thyroid. 2024;34:295. doi:10.1089/thy.2023.0556

We explored the effects of selenium supplementation in patients suffering from Hashimoto thyroiditis (HT), a leading cause of hypothyroidism. By analyzing multiple randomized controlled trials, we aimed to see how selenium might impact thyroid function, particularly focusing on thyroid-stimulating hormone (TSH) levels and thyroid antibodies.

Our analysis included results from 35 studies, where we observed that selenium supplementation led to a notable decrease in TSH levels among patients not undergoing thyroid hormone replacement therapy. This suggests that selenium may help manage thyroid function in specific populations.

Additionally, we found that selenium also reduced levels of thyroid peroxidase antibodies (TPOAb) and malondialdehyde (MDA), which indicates improved thyroid health and reduced oxidative stress. Interestingly, we observed that these benefits occurred irrespective of whether patients were receiving thyroid hormone therapy.

However, we did not find significant changes in other thyroid hormones or immune markers, indicating that while selenium can be effective in some areas, its benefits may not extend across all measures of thyroid health. Overall, our findings support the safe use of selenium in lowering TSH and certain antibodies in HT patients not on hormone therapy.

Positive thyroid effects

Most Useful Review

82 people found this helpful

This selenium is pure and yeast-free, with an excellent dosage. It's vital for hypothyroidism as it positively impacts thyroid function and benefits various body systems.

Updated: Mar 2026

Obesity details

It aids weight loss, particularly for those suffering from obesity. Selenium plays a crucial role in producing thyroid hormones that regulate various metabolic processes, including calorie burning.

Selenium's role in wart treatment

Warts details

De Luca C, Kharaeva Z, Raskovic D, Pastore P, Luci A, et al. Coenzyme Q(10), vitamin E, selenium, and methionine in the treatment of chronic recurrent viral mucocutaneous infections. Nutrition. 2012;28:509. doi:10.1016/j.nut.2011.08.003

We examined the effects of a nutritional approach involving selenium, among other supplements, on treating relapsing warts caused by the human papillomavirus. In a controlled trial with 68 patients, those treated with cryotherapy and followed up with nutriceuticals, including selenium, showed some beneficial clinical outcomes. However, the extent of selenium’s impact specifically on warts was not extensively detailed. Overall, we found that combining these nutrients with conventional therapy may assist in managing recurring infections more effectively.

Selenium works

Most Useful Review

After a month of taking selenium, the warts on my hands disappeared. I had tried various methods before, including removal and burning, but nothing worked. I highly recommend it, especially for the price. 👍

Updated: Apr 2025

Blood Clot details

Ebselen delays blood clot formation

Based on 9 Researches

Lindenblatt N, Schareck W, Belusa L, Nickels RM, Menger MD, et al. Anti-oxidant ebselen delays microvascular thrombus formation in the rat cremaster muscle by inhibiting platelet P-selectin expression. Thromb Haemost. 2003;90:882.

We explored the effects of ebselen, a selenium compound known for its antioxidant properties, on blood clot formation in rats. Our study demonstrated that ebselen significantly delayed thrombus formation in microvessels.

In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.

This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.

7.5

Helps muscle weakness

Most Useful Review

2 people found this helpful

If you're dealing with thyroid issues, especially autoimmunity, consult your doctor about this! I have Hashimoto's, and it's helped me immensely. After a couple of months on two tablets daily, my muscle weakness and twitches have significantly decreased. They are easy to swallow and are well absorbed, as shown in my blood work.

Updated: Mar 2026

Liver Disease details

Selenium nanoparticles reduce liver toxicity

Based on 15 Researches

Mrwad AA, El-Shafey SE, Said NM. Chitosan-encapsulated selenium nanoparticles alleviate CCl induced hepatotoxicity through synergistically modulating NF-κB and Nrf2 signaling pathways and regulating Bcl-2 and Caspase-3 expression: A comprehensive study with multiple regression analysis. J Trace Elem Med Biol. 2024;86:127563. doi:10.1016/j.jtemb.2024.127563

We investigated how selenium nanoparticles (Se-NPs) and chitosan-encapsulated selenium nanoparticles (Se-CS-NPs) can mitigate liver toxicity induced by carbon tetrachloride (CCl) in rats. In our study, eighty rats were divided into eight groups, including placebo and control.

The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.

7.5

Good nutritional supplement

Most Useful Review

This is an excellent nutritional supplement that benefits the liver, featuring natural ingredients and attractive packaging.

Updated: Mar 2026

Psoriasis details

This product is fantastic for skin conditions! It helped me with my psoriasis and acne.

Arthritis details

Beneficial for health

I purchased this product because I've heard it helps with cancer and arthritis. I don’t expect to feel immediate effects from health products, but I believe that the added supplements are beneficial for overall health.

Menopause details

Cognition enhancement in menopause

Based on 5 Researches

da Rocha JT, Pinton S, Mazzanti A, Mazzanti CM, Beckemann DV, et al. Diphenyl diselenide ameliorates cognitive deficits induced by a model of menopause in rats. Behav Pharmacol. 2012;23:98. doi:10.1097/FBP.0b013e32834ed849

We investigated how diphenyl diselenide, a synthetic selenium compound, affects cognitive performance in a rat model of menopause. Female rats underwent ovariectomy, mimicking hormone loss in postmenopausal women, and were treated with diphenyl diselenide daily for 30 days.

The results showed that this treatment improved cognitive abilities, as evidenced by better performance in behavioral tests and prevented the increase of acetylcholinesterase activity.

Overall, diphenyl diselenide appears to hold promise in mitigating cognitive decline linked to menopause.

Regulates hormones effectively

Most Useful Review

1 people found this helpful

I purchased this product at my doctor's recommendation. After ensuring the ingredient quality and dosage were correct, I've noticed significant improvements, especially in my hormonal regulation. Taken with other supplements, it greatly alleviated my menopause symptoms and their frequency. The taste is quite pleasant, making it easy to consume.

Updated: Mar 2026

Sleep Apnea details

Examined antioxidants in sleep apnea

Saruhan E, Sertoglu E, Unal Y, Bek S, Kutlu G. The role of antioxidant vitamins and selenium in patients with obstructive sleep apnea. Sleep Breath. 2021;25:923. doi:10.1007/s11325-020-02207-w

We examined the levels of selenium and key vitamins in patients suffering from obstructive sleep apnea (OSA) without additional health issues. Our study, involving 146 subjects split into different OSA severity levels, aimed to understand how these antioxidants might play a role in OSA's impact on health.

Interestingly, we found that higher concentrations of selenium and vitamin A appeared to bolster the body’s defense against OSA. Although our findings suggest potential benefits, it's important to note that antioxidants alone should not replace conventional treatments for OSA.

Energy and mood boost

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Very good selenium. On the third day of taking it, I noticed increased energy, a good mood, and improved sleep.

Updated: Mar 2026

Cancer details

Selenium drug shows selective toxicity

Based on 27 Researches

Qin X, Guo J, Li H, He H, Cai F, et al. Selenium Electrophilic Center Responsive to Biological Electron Donors for Efficient Chemotherapy. Adv Sci (Weinh). 2025. doi:10.1002/advs.202412062

We examined how a selenium-containing drug, known as RuSe, targets cancer cells while sparing normal cells. This innovative approach leverages the unique properties of selenium, specifically its electrophilic center, to create oxidative stress within cancer cells. By shuttling electrons from biological electron donors, the drug activates a sequence of events detrimental to cancer survival.

The results were striking; we found that the rate of electron transfer at the selenium site is significantly higher in cancer cells compared to normal cells—1.81 times greater, to be precise. This selective action leads to a lethal effect, with the drug being 14.98 times more harmful to cancer cells than to their healthy counterparts. We observed that the generation of superoxide anions from this process causes DNA damage and triggers the p53 signaling pathway, which enhances the drug's effectiveness in killing cancer cells.

Our findings offer an exciting new avenue for crafting chemotherapeutic agents that can be both efficient and less toxic. By exploiting the special properties of selenium, we open the door to more intelligent and targeted cancer therapies that could reduce side effects for patients.

Reduces cancer risk

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11 people found this helpful

Antioxidant selenium is essential! Who wants to get sick and age quickly? I recommend daily intake; it's excellent for health as it has anti-inflammatory, anti-atherosclerotic, and anti-tumour effects. It promotes hair growth and helps mitigate environmental damage. This element can reduce cancer incidence by 40% and cancer mortality by 50%. Cancer research confirms that selenium is a powerful immunostimulatory agent with a wide array of health benefits.

Updated: Mar 2026

Chronic Fatigue Syndrome details

Selenium effects on chronic fatigue

Based on 3 Researches

Shao C, Song J, Zhao S, Jiang H, Wang B, et al. Therapeutic Effect and Metabolic Mechanism of A Selenium-Polysaccharide from Green Tea on Chronic Fatigue Syndrome. Polymers (Basel). 2018;10. doi:10.3390/polym10111269

We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.

Great overall health

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4 people found this helpful

After two months of selenium, I feel fantastic. My skin glows, my mood has improved, and my fatigue has dissipated. I believe this is one of the best products for overall health maintenance, and the tablets are easy to swallow.

Updated: Mar 2026

Dizziness details

I have been taking selenium almost daily for two to three months, along with other supplements. The outcome has been positive; I've started to feel more cheerful and calm. Dizziness has ceased to trouble me.

Hyperthyroidism details

Significant improvement

Taken for hyperthyroidism, I have found it remarkably effective. The tablets are small, round, and tasteless. I have been taking them for over 4 months, and my thyroid-related levels have greatly improved. I successfully reduced my hospital medications from three to two. It's recommended to consume one tablet daily for consistent results. I’m pleased with the outcome and plan to maintain this routine.

Prostate Cancer details

Selenium nanoparticles show promise

Bissardon C, Proux O, Gazze SA, Filhol O, Toubhans B, et al. Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells. Nanomaterials (Basel). 2023;13. doi:10.3390/nano13232999

We explored the impact of selenium nanoparticles, known for their potential anti-cancer properties, on aggressive prostate cancer cells, specifically the PC-3 line. The study focused on understanding how sub-toxic levels of selenium functionalized nanoparticles affect cell proliferation and their intracellular behavior.

By utilizing advanced imaging techniques and careful cryopreparation, we aimed to preserve the integrity of the cancer cells while analyzing the distribution of these nanoparticles within them. Our findings revealed that nanoparticles coated with bovine serum albumin (BSA) reduced the migration capability of the cancer cells more effectively than those coated with chitosan.

This difference may be attributed to the BSA coating's ability to prevent harmful interactions with the cell membranes, which in turn limits the generation of reactive oxygen species that can damage cells. Most intriguingly, we observed that these selenium nanoparticles localized in both the mitochondria and lysosome-related organelles within the cells. The presence of nanoparticles in the mitochondria might explain the significant reduction in the PC-3 cells' ability to proliferate.

Overall, our investigation highlights the promising role selenium nanoparticles can play in cancer treatment strategies, providing valuable insights for further research into their cytotoxic mechanisms against prostate cancer.

No adverse reactions

Most Useful Review

It worked perfectly without causing any bodily reactions. It combats cancer, although the smell is not very pleasant.

Updated: Apr 2025

Brain Tumor details

Immune system booster

96 people found this helpful

Excellent! Selenium plays a vital role in bolstering the immune system and enhancing brain function. I highly recommend it.

Selenium has provided me with substantial relief, easing pain in my small joints, leg muscles, kidneys (urolithiasis), and thyroid gland (hypothyroidism). Since taking selenium, I can easily walk for several hours without heaviness in my legs, a marked improvement from the past. Additionally, I can now work at the computer for much longer without suffering from carpal tunnel syndrome.

Irritable Bowel Syndrome details

Allergies details

Selenium nanoparticles reduce allergies

Based on 12 Researches

Xie B, Zeng D, Yang M, Tang Z, He L, et al. Translational Selenium Nanoparticles to Attenuate Allergic Dermatitis through Nrf2-Keap1-Driven Activation of Selenoproteins. ACS Nano. 2023;17:14053. doi:10.1021/acsnano.3c04344

We examined how selenium, a trace element known for its role in health, can help those suffering from allergic dermatitis. In our exploration, we focused on how selenium nanoparticles, specifically designed for easier manufacturing and use, can activate the body's natural defenses against allergies.

The study highlighted how selenium impacts allergic reactions by enhancing the production of selenoproteins, which are crucial in regulating inflammation and oxidative stress. We saw that these selenium nanoparticles effectively inhibited mast cell activation. Mast cells are known to release substances that can trigger allergic reactions, so by reducing their activation, the potential for severe allergic responses decreased.

Additionally, through a series of experiments on allergic mouse models, we confirmed the nanoparticles increased selenium levels in the skin, which led to a reduction in inflammatory cells and mast cell activation. The results indicated significant therapeutic benefits, providing a promising avenue for managing allergic reactions.

Ultimately, this study not only demonstrates the innovative use of selenium nanoparticles in treating allergies but also emphasizes the importance of scaling up their production for broader clinical application.

Hoping for results

Most Useful Review

I take this as directed by my doctor, and it has not caused any allergies. I am hopeful for positive test results.

Updated: Mar 2026

Constipation details

Constipation improvement

I really appreciated this product; I've been taking it for over two weeks, and I can feel the results. Having suffered from constipation for ages and tried various remedies, my nutritionist recommended this supplement. Since taking it alongside omega-3 and vitamin D3, I experience almost no constipation now.

Low Libido details

Improved sperm quality

267 people found this helpful

We purchased selenium to enhance the quality of my husband's sperm as we are planning for a baby. It improves sperm motility and stimulates maturation. Selenium deficiency can lead to low libido, but it helps the body produce testosterone, which impacts sexual behaviour and libido, as well as erections and ejaculation. After a month of taking selenium, we saw a significant improvement in the sperm results, leading to the much-awaited two stripes. For anyone facing similar issues, I suggest combining it with zinc and vitamin E. Wishing everyone good health!

Food Poisoning details

Effect of SeNPs on ZEA toxicity

Based on 4 Researches

Qiao L, Chang J, Yang G, Deng T, Liu P, et al. Prophylactic supplementation with selenium nanoparticles protects against foodborne toxin zearalenone-induced intestinal barrier dysfunction. Ecotoxicol Environ Saf. 2024;284:116914. doi:10.1016/j.ecoenv.2024.116914

We explored the protective effects of selenium nanoparticles (SeNPs) against the harmful impacts of zearalenone (ZEA), a toxin from grains that can disrupt gut health. In a controlled setting, we observed that ZEA damages intestinal cells, leading to inflammation and increased permeability.

Our findings showed that SeNPs can counteract this damage by enhancing antioxidant activity and improving gut microbiota balance. Despite these promising results, it’s crucial to note that the effectiveness of SeNPs in humans still requires further investigation.

Effective for autoimmune issues

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2 people found this helpful

I take Selenium as recommended by my endocrinologist for autoimmune thyroiditis, and it significantly improves my performance. It’s a primary remedy for this condition, and I believe the quality from Now Foods exceeds that of local brands!

Updated: Mar 2026

Bacterial Infection details

Selenium bandages prevent infections

Tran P, Abidi N, Bergfeld N, Shashtri M, Reid TW. Selenium Bandages and Cotton Cloth That Kill Microorganisms in Wounds. Mil Med. 2024;189:179. doi:10.1093/milmed/usae069

We investigated how selenium-infused bandages can help prevent bacterial infections in wounds. By attaching organo-selenium compounds to cotton fabric, we created a bandage designed to kill harmful bacteria, including strains resistant to traditional antibiotics, like MRSA.

In our study, we used a mouse model to simulate wound infections. We placed the selenium-coated bandages on wounds and introduced bacteria directly into the area underneath the bandages. After five days, we examined the wounds and the bandages for signs of bacterial growth.

Remarkably, we observed that the bandages effectively protected the wounds, showing no bacterial presence after the five days of monitoring. This suggests that selenium remains effective even after washing, potentially offering a new approach to managing infections in medical settings.

Enhances immune system

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Selenium is crucial for immune function. Insufficient levels can increase infection rates. This supplement has been shown to enhance the performance of white blood cells, helping to combat both infections and cancers.

Updated: Mar 2026

Heart Disease details

Selenium nanoparticles support heart health

Chen C, Ma J, Duan S, Xue M, Yang Z, et al. Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation. Biomaterials. 2025;318:123119. doi:10.1016/j.biomaterials.2025.123119

We explored how selenium nanoparticles (SeNPs) could help reduce damage from heart attacks, specifically ischemia/reperfusion injury (I/RI). Using a method to create these nanoparticles, we found they possess remarkable properties that combat oxidative stress and inflammation.

SeNPs seem to disrupt harmful cellular cycles, thereby protecting heart cells. Notably, they improved heart function and reduced cell death and scar tissue in tests. Overall, these findings suggest that SeNPs could be a valuable approach in managing heart conditions after a heart attack.

7.5

Improves heart health

Most Useful Review

185 people found this helpful

Selenium is an essential trace element that aids the body in combating oxidative damage, maintaining normal thyroid and immune functions, and enhancing heart and brain health. It also supports healthy cell division. I take it as prescribed by my doctor, and I am very pleased with the results.

Updated: Mar 2026

Blurred Vision details

Selenium shows short-term benefits only

Wang C, Qiao J, Liu S, Piao S, Zhou Y, et al. Selenium in the treatment of mild-to-moderate Graves' orbitopathy: a 5-year prospective controlled cohort study. Endocrine. 2024;84:1072. doi:10.1007/s12020-023-03672-5

Our study examined the effects of selenium in treating mild-to-moderate Graves' orbitopathy (GO) over five years. We followed 74 patients who took selenium or a placebo for six months, tracking their symptoms and quality of life.

Initially, selenium showed promise by reducing symptoms like blurred vision, with significant improvements over six months. However, when we looked at long-term outcomes after five years, both groups had similar results, indicating that while selenium may help in the short term, it doesn't contribute to lasting changes.

7.5

Supports visual acuity

Most Useful Review

5 people found this helpful

This selenium supplement is vital for the biosynthesis of protein molecules and nucleic acids. The stable functioning of the nervous system greatly relies on biologically available selenium. This trace element supports visual acuity and concentration levels. It is also essential for the maturation of male germ cells and contributed to men’s sexual function, as it has anti-inflammatory effects.

Updated: Mar 2026

Diarrhea details

Probiotics are beneficial for reducing gas and bloating, as well as in preventing and treating diarrhoea and constipation. Science validates that they can help avert chronic gut inflammation and infections, alleviating symptoms of irritable bowel syndrome.

The mineral that women require. This dietary supplement is yeast-free, hence it does not cause heartburn or swelling, unlike the previous one I tried. This one was fine. I recommend it.

Heartburn details

Headache details

Selenium shows promise for migraines

Based on 3 Researches

Balali A, Sadeghi O, Khorvash F, Rouhani MH, Askari G. The effect of selenium supplementation on oxidative stress, clinical and physiological symptoms in patients with migraine: a double-blinded randomized clinical trial. Front Nutr. 2024;11:1369373. doi:10.3389/fnut.2024.1369373

We explored the effects of selenium supplementation in a double-blinded trial involving 72 patients with migraines. Over 12 weeks, participants received either selenium or a placebo. We observed that those taking selenium experienced reduced headache frequency and severity.

Additionally, selenium improved antioxidant levels and lowered oxidative stress markers. However, it appears that many other factors related to migraine symptoms did not see significant changes. While this research shows promise, further studies are necessary to confirm these findings.

Headache completely faded

Most Useful Review

1 people found this helpful

I've started feeling better since beginning selenium, which I take with vitamin D and C. My mood has lifted, and my headache has completely faded away.

Updated: Mar 2026

Nausea details