Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Fish Oil Concentrate
1.3 g (1,300 mg)
†
Docosahexaenoic Acid (DHA)
1 g (1,000 mg)
†
The product is found useful for the following medical conditions
Alzheimer details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.2
USERS' SCORE
Good
Based on 2 Reviews
8.7
9
DHA shows promise in Alzheimer's
Nose-to-brain delivery of DHA-loaded nanoemulsions: A promising approach against Alzheimer's disease.
Most Relevant Research
We investigated the potential benefits of docosahexaenoic acid (DHA) in fighting Alzheimer's disease (AD) through a novel intranasal administration method. By using a specially formulated nanoemulsion that protects DHA from oxidation, we aimed to enhance its delivery to the brain. In our study, we administered this DHA-rich nanoemulsion to J20 mice, a well-known transgenic model for AD.
The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.
Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients.
The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.
Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients.
9.5
Powerful supplement effects
Most Useful Review
Wow! This is a tremendously powerful supplement! It significantly improves memory and supports brain health against Alzheimer’s and other dementia types. 1000mg daily is the ideal dose for noticeable results. There are endless benefits from this supplement, and I wholeheartedly recommend it for neurogenesis and overall cognitive health.
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.7
9.5
Very effective product
Most Useful Review
Excellent vitamins! The price is quite reasonable, and the delivery was rapid. The quality is superb with natural ingredients that enhance health. The capsules are small and convenient to take. I have noticed an improvement in my immunity, and the packaging is of high quality. This product effectively addresses deficiency and has significantly strengthened my bones. I recommend it to everyone, including my family and friends, and we consistently purchase this specific brand. It’s a very effective vitamin supplement.
Sleep Apnea details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 11 Reviews
8.7
8
DHA levels linked to OSA severity
Membrane level of omega-3 docosahexaenoic acid is associated with severity of obstructive sleep apnea.
Most Relevant Research
We investigated how the omega-3 fatty acid docosahexaenoic acid (DHA) impacts the severity of obstructive sleep apnea (OSA) in 350 patients undergoing sleep studies. Our study aimed to determine if there is a relationship between the levels of DHA in red blood cells (RBC) and the severity of sleep apnea, categorized as none/mild, moderate, or severe based on apnea hypopnea index (AHI) scores.
Our findings revealed that lower levels of DHA are linked to more severe cases of OSA. For each standard deviation increase in DHA, patients were about 50% less likely to be classified in the severe apnea category. Specifically, we noted decreased odds of falling into the severe OSA group when DHA levels were higher, suggesting that DHA may play an important role in the severity of this condition.
These insights imply that maintaining healthy DHA levels could potentially influence OSA severity and could aid in developing treatment strategies. We believe that future research should explore the potential benefits of DHA supplementation for those suffering from sleep apnea.
Our findings revealed that lower levels of DHA are linked to more severe cases of OSA. For each standard deviation increase in DHA, patients were about 50% less likely to be classified in the severe apnea category. Specifically, we noted decreased odds of falling into the severe OSA group when DHA levels were higher, suggesting that DHA may play an important role in the severity of this condition.
These insights imply that maintaining healthy DHA levels could potentially influence OSA severity and could aid in developing treatment strategies. We believe that future research should explore the potential benefits of DHA supplementation for those suffering from sleep apnea.
9.5
Immediate sleep improvement
Most Useful Review
TOP! I noticed immediate improvements in sleep quality, reasoning, and general health. I highly recommend it.
Blurred Vision details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.6
9
Significant improvement
Most Useful Review
This product is certainly worth trying. It has significantly enhanced my brain health and vision. After using it for a brief period, I noticed notable improvements. The taste is pleasant, and I can easily consume it daily. I have relied on this product for a long time, and the results have been outstanding. My overall health has greatly improved, and I feel more energised than ever. NOW DHA-1000 has provided excellent balance to both my mind and body. I feel refreshed and revitalised.
Brain Tumor details
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.3
USERS' SCORE
Good
Based on 30 Reviews
8.6
8
DHA liposomes show promise
Microfluidic-derived docosahexaenoic acid liposomes for glioblastoma therapy.
Most Relevant Research
We explored an innovative approach to treating glioblastoma, the most common malignant brain tumor, by utilizing docosahexaenoic acid (DHA) liposomes. These liposomes were created using a microfluidic system that allowed for fine-tuning various properties, which could enhance their effectiveness in targeting tumor cells.
Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.
Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
Our findings revealed that these DHA liposomes, ranging in size from 80 nm to 130 nm, were successfully taken up by glioblastoma cells. This uptake was promising, as we saw a reduction in the viability of these cancerous cells. Interestingly, we also observed that DHA liposomes were significantly better at triggering cell death mechanisms compared to free DHA, specifically through pathways that involved caspase-3.
Overall, our study suggests that these microfluidic-derived DHA liposomes might offer new avenues for developing therapies using omega-3 fatty acids against brain tumors, potentially leading to more effective treatment options in the future.
9.5
Improved memory
Most Useful Review
Very effective! I experienced clarity and improved memory. By the second day, my brain felt much more active, and my speech was noticeably faster. I truly enjoy this product!
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.6
9
Essential fatty acids aid fatigue syndrome
Effect of high doses of essential fatty acids on the postviral fatigue syndrome.
Most Relevant Research
We conducted a study to evaluate the effectiveness of essential fatty acids, particularly docosahexaenoic acid (DHA), in treating postviral fatigue syndrome, which affects many individuals after a viral infection.
In a double-blind, placebo-controlled setup involving 63 adults, we administered a mixture of essential fatty acids to half of the participants while the other half received a placebo. Each person received eight capsules daily for three months, and we checked their overall condition, fatigue, and other symptoms at various points throughout the study.
Excitingly, we observed significant improvements among those taking the active treatment. After just one month, 74% of participants in the DHA group felt better compared to only 23% in the placebo group. That number rose to 85% at the three-month mark, indicating that while the placebo group reverted to their initial state, those receiving essential fatty acids continued to improve.
Additionally, we saw that the fatty acid levels in patients’ blood cells normalized with treatment, and there were no adverse effects reported. Overall, our findings suggest that DHA, as part of a broader essential fatty acid approach, is a safe and beneficial option for those suffering from postviral fatigue syndrome.
In a double-blind, placebo-controlled setup involving 63 adults, we administered a mixture of essential fatty acids to half of the participants while the other half received a placebo. Each person received eight capsules daily for three months, and we checked their overall condition, fatigue, and other symptoms at various points throughout the study.
Excitingly, we observed significant improvements among those taking the active treatment. After just one month, 74% of participants in the DHA group felt better compared to only 23% in the placebo group. That number rose to 85% at the three-month mark, indicating that while the placebo group reverted to their initial state, those receiving essential fatty acids continued to improve.
Additionally, we saw that the fatty acid levels in patients’ blood cells normalized with treatment, and there were no adverse effects reported. Overall, our findings suggest that DHA, as part of a broader essential fatty acid approach, is a safe and beneficial option for those suffering from postviral fatigue syndrome.
9.5
Boosted memory
Most Useful Review
DHA-100 is superb! My first order and one of my best purchases. With a good composition and high DHA concentration, it performs excellently. My attention, memory, and concentration have improved significantly. My productivity is up, and fatigue is hardly noticeable.
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.6
8
DHA intake may reduce migraines
The relationship between different fatty acids intake and frequency of migraine attacks.
Most Relevant Research
We assessed the effects of fatty acids, particularly docosahexaenoic acid (DHA), on migraine frequency in a group of 105 participants aged 15 to 50. Our study found a clear relationship: lower DHA intake correlated with a higher frequency of migraine attacks. This was consistent across both men and women. However, no significant link was found between saturated fatty acids and migraine frequency. Our findings suggest that increasing omega-3 fatty acids like DHA could potentially help reduce migraine occurrences, though more research is needed in this area.
9.5
Improved memory
Most Useful Review
Excellent vitamins for brain activity and memory! We've been using them for three weeks now, and I've noticed a significant improvement in my memory, and the headaches have disappeared.
Heart Attack details
SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.4
USERS' SCORE
Good
Based on 2 Reviews
8.6
2
No significant impact on NT-proBNP
No effect of n-3 fatty acids supplementation on NT-proBNP after myocardial infarction: the Alpha Omega Trial.
Most Relevant Research
We explored the effects of omega-3 fatty acids, specifically EPA and DHA, on heart failure markers in patients who had suffered a heart attack. In a large study involving nearly 4,837 participants aged 60-80, we administered various types of margarine for 40 months, some enriched with these fatty acids.
However, our results indicated that there was no significant change in NT-proBNP levels, a crucial heart failure biomarker, among those taking the supplements compared to a placebo group. Thus, it appears that modest EPA and DHA supplementation does not significantly affect heart failure risks after a myocardial infarction.
However, our results indicated that there was no significant change in NT-proBNP levels, a crucial heart failure biomarker, among those taking the supplements compared to a placebo group. Thus, it appears that modest EPA and DHA supplementation does not significantly affect heart failure risks after a myocardial infarction.
8.8
Energises heart health
Most Useful Review
Good old fish oil! I have used this product for many years, and it has always been beneficial. It's especially helpful for health when combined with Coenzyme Q10, as the heart seems to receive an energy boost. Gelatin is also beneficial for skin, hair, and nails.
Heart Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 32 Researches
7.4
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
High-dose omega-3 aids heart health
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
Most Relevant Research
We examined how different doses and durations of omega-3 fatty acids (PUFAs) affect heart failure management. Our study analyzed data from 14 randomized controlled trials, involving nearly 9,100 participants. We found that high doses of omega-3 (2000-4000 mg daily) for at least a year significantly improved heart function, particularly left ventricular ejection fraction and peak oxygen consumption. However, lower doses and shorter durations didn't yield the same benefits, and no increased risk of adverse events was noted. More research is needed to solidify these results.
8.8
Good for heart health
Most Useful Review
It has a mild flavour and is beneficial for heart health, inflammation, and lowering cholesterol. The Now brand is reputable and suitable for all ages; I recommend it.
Cardiovascular Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 27 Researches
7.6
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
High-dose omega-3s improve heart function
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
Most Relevant Research
We explored the effectiveness of omega-3 fatty acid (PUFA) supplements in improving heart failure. Through a comprehensive network meta-analysis, we examined data from 14 randomized controlled trials involving over 9,000 participants.
Our findings showed that taking high doses of omega-3s (2000-4000 mg daily) for a year or more led to significant improvements in heart function, specifically in left ventricular ejection fraction and peak oxygen consumption. However, lower doses or shorter use didn’t yield these benefits, and there were no notable increases in dropout rates or overall mortality.
This suggests that while omega-3s can be beneficial for heart function in heart failure patients, careful consideration of the dosage and duration is essential.
Our findings showed that taking high doses of omega-3s (2000-4000 mg daily) for a year or more led to significant improvements in heart function, specifically in left ventricular ejection fraction and peak oxygen consumption. However, lower doses or shorter use didn’t yield these benefits, and there were no notable increases in dropout rates or overall mortality.
This suggests that while omega-3s can be beneficial for heart function in heart failure patients, careful consideration of the dosage and duration is essential.
8.8
Enhanced well-being
Most Useful Review
DHA, or docosahexaenoic acid, has been a total game-changer for me. Since incorporating it into my daily routine, I have noticed a remarkable improvement in my overall well-being. It has enhanced my cognitive function and mental clarity, boosted my mood, and provided sustained energy throughout the day. The anti-inflammatory properties of DHA also alleviate joint discomfort and support my cardiovascular health. Knowing that I’m nourishing my body with this essential omega-3 fatty acid gives me peace of mind, and I highly recommend DHA to anyone aiming to optimise their health and unlock their full potential.
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7
USERS' SCORE
Good
Based on 2 Reviews
8.5
8
DHA shows potential for depression
The Efficacy of Omega-3 Fatty Acids as the Monotherapy for Depression: A Randomized, Double-Blind, Placebo-Controlled Pilot Study.
Most Relevant Research
We conducted a study to find out whether docosahexaenoic acid (DHA), a type of omega-3 fatty acid, could effectively help those dealing with major depressive disorder (MDD). Over the course of 12 weeks, 60 participants were involved in a double-blind, placebo-controlled trial. They were divided into two groups: one received 3.2 grams of DHA daily, while the other group was given an equivalent amount of soybean oil as a placebo.
Throughout the study, we measured depression levels using the Hamilton Rating Scale for Depression (HRSD). Our results were intriguing—those taking the DHA showed significant improvements in their depression scores compared to the placebo group by weeks 4, 6, 8, and 12. While we noted that 26.7% of participants receiving DHA achieved remission by week 12, this was not statistically significant in comparison to the placebo group.
Overall, our findings support the idea that DHA may serve as a promising alternative treatment for individuals suffering from MDD. Although the results are encouraging, we recognize the need for further research to confirm these benefits conclusively.
Throughout the study, we measured depression levels using the Hamilton Rating Scale for Depression (HRSD). Our results were intriguing—those taking the DHA showed significant improvements in their depression scores compared to the placebo group by weeks 4, 6, 8, and 12. While we noted that 26.7% of participants receiving DHA achieved remission by week 12, this was not statistically significant in comparison to the placebo group.
Overall, our findings support the idea that DHA may serve as a promising alternative treatment for individuals suffering from MDD. Although the results are encouraging, we recognize the need for further research to confirm these benefits conclusively.
8.3
Mind balanced
Most Useful Review
Replying to @serenity: Girls, this is amazing. I swear, for my soul and anyone who has depression, taking vitamin D is essential. It has made my mind balanced and alert.
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.8
USERS' SCORE
Good
Based on 5 Reviews
8.3
9
DHA shows promise for autoimmunity
Neuroprotective and antioxidant effects of docosahexaenoic acid (DHA) in an experimental model of multiple sclerosis.
Most Relevant Research
We conducted a study to evaluate how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, can impact autoimmune disorders, specifically using an animal model of multiple sclerosis (MS). In this investigation, we worked with twenty-five Dark Agouti rats, dividing them into distinct groups. Some received DHA, while others served as controls, allowing for comparisons of its effectiveness on clinical symptoms and levels of oxidative stress.
Over the course of 51 days, DHA was administered via injections, with a daily 40 mg/kg dosage given five days a week. What we observed was quite encouraging. The DHA supplementation appeared to lead to a reduction in oxidative stress markers and showed improvements in clinical scores related to the disease. These results suggest that DHA has the potential to positively influence the progression of MS.
Furthermore, we believe this effect may be linked to DHA’s ability to activate Nrf2, an important antioxidant factor in our bodies. Overall, our findings indicate that DHA could be a beneficial treatment option for managing multiple sclerosis and possibly other autoimmune conditions.
Over the course of 51 days, DHA was administered via injections, with a daily 40 mg/kg dosage given five days a week. What we observed was quite encouraging. The DHA supplementation appeared to lead to a reduction in oxidative stress markers and showed improvements in clinical scores related to the disease. These results suggest that DHA has the potential to positively influence the progression of MS.
Furthermore, we believe this effect may be linked to DHA’s ability to activate Nrf2, an important antioxidant factor in our bodies. Overall, our findings indicate that DHA could be a beneficial treatment option for managing multiple sclerosis and possibly other autoimmune conditions.
9.5
Increased energy
Most Useful Review
No longer feeling like a sleepy fly! I’ve ordered this product a second time for myself and also for my sister; it’s fantastic! I feel my performance has improved and drowsiness has completely vanished. I've even found the motivation to write this review! I highly recommend it, especially to those who feel the urge to fall asleep right after dinner. A downside is the price reduction of 400 rubles over the past three months, but despite that, this Omega is the best, with a 1000 DHA content that I can't find elsewhere!
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.5
USERS' SCORE
Good
Based on 3 Reviews
8.2
8
DHA may reduce blood clots
Potential Benefits of Omega-3 Polyunsaturated Fatty Acids (N3PUFAs) on Cardiovascular Health Associated with COVID-19: An Update for 2023.
Most Relevant Research
We delved into the benefits of docosahexaenoic acid (DHA) in relation to blood clotting, especially in the context of cardiovascular health and COVID-19. DHA, a form of omega-3 fatty acid, shows promise in influencing how our body's clotting mechanism works. By integrating into cell membranes, DHA helps reduce inflammation and support overall epithelial function.
Studies indicate a positive link between increased DHA intake and lower risks of thrombotic outcomes, suggesting that it may be beneficial for those at risk of blood clots. The research highlights that both DHA and its counterpart, eicosapentaenoic acid (EPA), play a role in creating bioactive compounds that support cardiovascular health.
Given its safety profile, DHA emerges as a potential adjunctive treatment for individuals vulnerable to cardiovascular issues due to COVID-19. We also consider the optimal forms and dosages for maximum effectiveness, showing how accessible nutrition can aid in maintaining better heart health.
Studies indicate a positive link between increased DHA intake and lower risks of thrombotic outcomes, suggesting that it may be beneficial for those at risk of blood clots. The research highlights that both DHA and its counterpart, eicosapentaenoic acid (EPA), play a role in creating bioactive compounds that support cardiovascular health.
Given its safety profile, DHA emerges as a potential adjunctive treatment for individuals vulnerable to cardiovascular issues due to COVID-19. We also consider the optimal forms and dosages for maximum effectiveness, showing how accessible nutrition can aid in maintaining better heart health.
8.8
Mood enhancement
Most Useful Review
These Omega-3 vitamins are excellent—reducing the negative effects of stress on the nervous system, improving mood, acting as an antidepressant, and enhancing concentration and memory. They help normalise blood pressure and decrease the chances of developing cardiovascular diseases. The quality from this manufacturer is top-notch!
