Supplement Facts
Serving Size: 2 Teaspoons (10 ml)
Serving Per Container: 12
Amount Per Serving
%DV
Calories
25
Total Carbohydrate
7 g
3%†
Total Sugars
7 g
**
Includes 3.1 g Added Sugars
6.2%
Vitamin C (ascorbic acid)
110 mg
122%
Zinc (as zinc gluconate)
2.6 mg
24%
Black Elderberry Extract
3.8 g
**
The product is found useful for the following medical conditions
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 10 Reviews
8.7
9
No coughing, sneezing
Most Useful Review
203 people found this helpful
A great remedy! If I notice the first signs of a cold, I immediately give it to my child, and by the next day, there's no coughing or sneezing.
Cough details
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.5
USERS' SCORE
Good
Based on 82 Reviews
8.7
2
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
9
No cough symptoms
Most Useful Review
203 people found this helpful
A fantastic product! As soon as I notice the first signs of a cold, I administer it to my child, and by the following day, there is no coughing or sneezing.
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 19 Reviews
8.5
9
Instant relief experienced
Most Useful Review
2 people found this helpful
A high-quality supplement with useful ingredients! I give my mother this syrup at the first signs of a cold. The result is immediate; she reports instant relief in her throat. It tastes excellent, and the composition is outstanding. It's a great syrup for my family.
Autoimmune Disorder details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
USERS' SCORE
Good
Based on 7 Reviews
8.5
9
We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
9
Immunity booster
Most Useful Review
7 people found this helpful
Sambucol Black Elderberry Syrup has been wonderful at the onset of a cold. I value its immune-boosting properties, especially since my daughter has shown rapid improvement in her health after starting this syrup twice daily at the first sign of illness. I am very pleased with its effectiveness.
Common Cold details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
USERS' SCORE
Good
Based on 56 Reviews
8.5
9
We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
9
Faster cold recovery
Most Useful Review
290 people found this helpful
Excellent medication; undoubtedly the best from this brand. At the initial symptoms of a cold, the immune support is exceptional. I buy it for my children and have noticed the results. Their colds genuinely pass more swiftly and easily compared to other children in their class, especially when used alongside other treatments. It boasts a significant amount of antioxidants and vastly outperforms other herbal remedies against the influenza virus. Black elder offers diaphoretic, bactericidal, and anti-inflammatory benefits. It’s most effective on the first day, hence should be taken as soon as symptoms arise. This remedy quickly helps us recover from ARVI and flu.
Flu details
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.7
USERS' SCORE
Good
Based on 86 Reviews
8.4
9
We delved into how elderberry, specifically from the black elderberry fruit, impacts the flu virus, H1N1. Using an innovative technique called Direct Analysis in Real Time Mass Spectrometry (DART TOF-MS), we were able to identify the powerful anti-viral properties of elderberry extract without the need for complicated processes like separation or derivatization.
Our findings revealed that elderberry extract does indeed inhibit H1N1 infection in a lab setting, with an effective concentration (IC50) of 252 micrograms per milliliter. Interestingly, we discovered that flavonoids present in the elderberry bind to H1N1 virions—essentially blocking their ability to infect host cells.
Among the compounds, two key flavonoids emerged: the 5,7,3',4'-tetra-O-methylquercetin and dihydromyricetin. These compounds not only bound to the virus but also effectively prevented infection. Notably, the tetra-O-methylquercetin demonstrated an impressive IC50 of just 0.13 micrograms per milliliter, which is comparable to well-known antiviral medications like Oseltamivir and Amantadine.
In summary, elderberry shows promising potential as a natural remedy against the H1N1 flu, offering a fascinating area for further research and utilization in flu prevention strategies.
Our findings revealed that elderberry extract does indeed inhibit H1N1 infection in a lab setting, with an effective concentration (IC50) of 252 micrograms per milliliter. Interestingly, we discovered that flavonoids present in the elderberry bind to H1N1 virions—essentially blocking their ability to infect host cells.
Among the compounds, two key flavonoids emerged: the 5,7,3',4'-tetra-O-methylquercetin and dihydromyricetin. These compounds not only bound to the virus but also effectively prevented infection. Notably, the tetra-O-methylquercetin demonstrated an impressive IC50 of just 0.13 micrograms per milliliter, which is comparable to well-known antiviral medications like Oseltamivir and Amantadine.
In summary, elderberry shows promising potential as a natural remedy against the H1N1 flu, offering a fascinating area for further research and utilization in flu prevention strategies.
9
Effective flu treatment
Most Useful Review
290 people found this helpful
Excellent drug. Probably the best among this brand. At the first symptoms of a cold, the immunity support is superb. I buy it for my children, and I see the results. Colds genuinely pass faster and easier than other children in the class. Of course, it works best in combination with other medications. It has a record amount of antioxidants and significantly outperforms other plants in fighting the influenza virus. Black elderberry has diaphoretic, bactericidal, and anti-inflammatory effects. It's particularly effective on the first day, so should be used when the initial symptoms of the illness appear. Thanks to this product, I quickly recover from ARVI and flu.
Liver Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.4
9
We evaluated how vitamin C, also known as ascorbic acid, can help protect the liver during procedures that temporarily cut off blood flow—a process known as ischaemia followed by reperfusion. In this study, we used thirty-six male Wistar rats, split into control groups and experimental ones. Each group received the same total dose of vitamin C, administered at different times: either before the ischaemia, before the reperfusion, or both.
Our findings showed that the animals given vitamin C before both the ischaemia and reperfusion had improved outcomes. They had lower levels of liver enzymes, indicating less liver damage, and showed reduced inflammation. Additionally, their portal blood flow was better when compared to the other groups. Overall, our results suggest that administering vitamin C at specific times can significantly reduce liver injury associated with ischaemia-reperfusion.
This study highlights the potential of vitamin C as a protective agent in situations where liver damage is a concern during surgeries or treatments involving blood flow disruption.
Our findings showed that the animals given vitamin C before both the ischaemia and reperfusion had improved outcomes. They had lower levels of liver enzymes, indicating less liver damage, and showed reduced inflammation. Additionally, their portal blood flow was better when compared to the other groups. Overall, our results suggest that administering vitamin C at specific times can significantly reduce liver injury associated with ischaemia-reperfusion.
This study highlights the potential of vitamin C as a protective agent in situations where liver damage is a concern during surgeries or treatments involving blood flow disruption.
9
Antioxidant properties highlighted
Most Useful Review
It is one of the premier tools in combating viruses, containing a record number of antioxidants and significantly outperforming other plants against the influenza virus. Black elderberry exhibits diaphoretic, bactericidal, and anti-inflammatory properties. Its effectiveness peaks on the first day, so it’s essential to use it upon the first symptoms of illness, enabling a swift recovery from ARVI and flu.
Bacterial Infection details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 6 Reviews
8.3
9
Prevented infection successfully
Most Useful Review
I've been taking this product since the start of the year and haven't fallen ill at all. Normally, I tend to experience sinus infections during winter or spring; however, this year, I’ve managed to stay healthy!
Pelvic Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8.3
9
Highly recommended syrup
Most Useful Review
This syrup is always part of my first aid kit! At the first sign of a cold, I give it to my child immediately. The pain is considerably lessened, and I definitely recommend it!
Cold details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.8
USERS' SCORE
Good
Based on 516 Reviews
8.2
8
We explored whether elderberry could help reduce the duration and severity of colds for economy class passengers traveling internationally. In a well-structured randomized, double-blind, placebo-controlled clinical trial involving 312 participants, we looked at how a standardized elderberry extract affected respiratory health during air travel.
Participants tracked their cold episodes, duration, and symptoms in daily diaries, using a scoring method to quantify their experiences. They also completed surveys about their upper respiratory symptoms and quality of life at different points: before traveling and four days post-travel.
While we noted that the group taking the placebo experienced more cold episodes, the difference wasn't statistically significant. However, those taking elderberry had a significantly shorter duration of cold days and a lower average symptom score overall, suggesting that elderberry may significantly lessen the impact of colds during air travel.
Further research is essential to validate our findings and to better understand the broader health benefits of elderberry, both physical and mental.
Participants tracked their cold episodes, duration, and symptoms in daily diaries, using a scoring method to quantify their experiences. They also completed surveys about their upper respiratory symptoms and quality of life at different points: before traveling and four days post-travel.
While we noted that the group taking the placebo experienced more cold episodes, the difference wasn't statistically significant. However, those taking elderberry had a significantly shorter duration of cold days and a lower average symptom score overall, suggesting that elderberry may significantly lessen the impact of colds during air travel.
Further research is essential to validate our findings and to better understand the broader health benefits of elderberry, both physical and mental.
9
Sos remedy
Most Useful Review
236 people found this helpful
This is a go-to remedy at the first sign of a cold. I highly recommend it.
Cardiovascular Disease details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 8 Reviews
8.1
9
We set out to investigate how zinc might help protect heart cells from damage caused by a lack of blood flow, known as myocardial ischemia-reperfusion injury (MIRI). Using H9C2 cells, which are derived from rat heart tissue, we simulated this injury by depriving these cells of oxygen and then reintroducing it while treating them with zinc.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
Through this process, we found that zinc treatment significantly increased cell viability compared to those that did not receive zinc. Cells exposed to ischemia showed typical signs of trauma, like heightened levels of apoptosis—or programmed cell death—and calcium overload, which can further damage cells.
Interestingly, zinc seemed to tackle these issues by lowering the levels of certain proteins related to cell death. It also played a role in regulating calcium levels by interacting with various cellular pathways. In fact, when we silenced specific proteins involved in these pathways, the protective benefits of zinc were even more pronounced.
Our findings suggest that zinc can relieve the harmful effects of ischemia by mitigating cell death and regulating calcium overload, which offers hope for future treatments for heart-related conditions impacted by blood flow interruptions.
7.5
Elderberry improves recovery
Most Useful Review
290 people found this helpful
Excellent medication. Likely the best from this brand. At the onset of a cold, the immune support is exceptional. I purchase it for my children and see the results. Colds pass significantly faster and easier than those of other children in the class, particularly when combined with other medications. It boasts a high content of antioxidants and outperforms other botanicals in combating the influenza virus. Black elder has diaphoretic, bactericidal, and anti-inflammatory properties. Most effective on the first day, so it should be administered when cold symptoms appear. Thanks to this remedy, I recover quickly from ARVI and flu.
Sore Throat details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.7
USERS' SCORE
Good
Based on 24 Reviews
8.1
9.5
We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
9
Effective improvement
Most Useful Review
Excellent! I truly love this syrup; it works well for me. At the sign of a sore throat, I drink some, and by the following day, I feel brilliant. It provides real benefits to my throat and has a lovely taste, with noticeable improvement soon after taking it.
Cold Sores details
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.3
USERS' SCORE
Good
Based on 37 Reviews
8
9
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
9
Excellent results reported
Most Useful Review
111 people found this helpful
At the first hint of a cold, it's essential to take it at night and in the morning! The effects are remarkable!
Bone Pain details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.9
7.5
Less pain
Most Useful Review
I bought this for my son due to its excellent composition. We see noticeable results, with less bone pain and fewer colds.
