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Supplement Facts
Serving Size: 2 Teaspoons (10 ml)
Serving Per Container: 12
Amount Per Serving
%DV
Calories
25
Total Carbohydrate
7 g
3%†
Total Sugars
7 g
**
Includes 3.1 g Added Sugars
6.2%
Vitamin C (ascorbic acid)
110 mg
122%
Zinc (as zinc gluconate)
2.6 mg
24%
Black Elderberry Extract
3.8 g
**
The product is found useful for the following medical conditions
Common Cold
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.6
USERS' SCORE
Excellent
Based on 56 Reviews
9
9
Zinc shortens cold duration variability
Quantile Treatment Effect of Zinc Lozenges on Common Cold Duration: A Novel Approach to Analyze the Effect of Treatment on Illness Duration.
Most Relevant Research
We explored how zinc lozenges affect the duration of the common cold through a detailed analysis of multiple trials. In particular, we focused on the Mossad (1996) trial involving zinc gluconate lozenges, which revealed an average reduction of cold duration by about 4.0 days. While that sounds promising, our findings through a quantile treatment effect (QTE) analysis tell a more nuanced story.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
Interestingly, the QTE analysis showed that for individuals suffering from lengthy colds lasting 15 to 17 days, the zinc lozenges could shorten their illness by as much as 8 days. On the flip side, those with shorter, 2-day colds only experienced a 1-day reduction in sickness. This suggests that while zinc may help, its effectiveness varies significantly depending on the initial duration of the cold, making the overall average effect less informative than we might think.
Our examination extended to three trials that used zinc acetate lozenges, yielding a similar average reduction of around 2.7 days. However, again, those averages concealed varying effects for short and long colds, highlighting the importance of looking beyond simple averages in treatment studies.
Overall, we observed that zinc lozenges can indeed help with cold duration, but the extent of that help is very much dependent on how long a person has been suffering. This approach to understanding treatment effects through QTE analysis could have important implications not just for cold treatment but also for analyzing other health outcomes.
9.5
Faster cold recovery
Most Useful Review
Excellent medication; undoubtedly the best from this brand. At the initial symptoms of a cold, the immune support is exceptional. I buy it for my children and have noticed the results. Their colds genuinely pass more swiftly and easily compared to other children in their class, especially when used alongside other treatments. It boasts a significant amount of antioxidants and vastly outperforms other herbal remedies against the influenza virus. Black elder offers diaphoretic, bactericidal, and anti-inflammatory benefits. It’s most effective on the first day, hence should be taken as soon as symptoms arise. This remedy quickly helps us recover from ARVI and flu.
Cold
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.8
USERS' SCORE
Good
Based on 2 Reviews
8.7
8
Elderberry reduces cold duration
Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial.
Most Relevant Research
We explored whether elderberry could help reduce the duration and severity of colds for economy class passengers traveling internationally. In a well-structured randomized, double-blind, placebo-controlled clinical trial involving 312 participants, we looked at how a standardized elderberry extract affected respiratory health during air travel.
Participants tracked their cold episodes, duration, and symptoms in daily diaries, using a scoring method to quantify their experiences. They also completed surveys about their upper respiratory symptoms and quality of life at different points: before traveling and four days post-travel.
While we noted that the group taking the placebo experienced more cold episodes, the difference wasn't statistically significant. However, those taking elderberry had a significantly shorter duration of cold days and a lower average symptom score overall, suggesting that elderberry may significantly lessen the impact of colds during air travel.
Further research is essential to validate our findings and to better understand the broader health benefits of elderberry, both physical and mental.
Participants tracked their cold episodes, duration, and symptoms in daily diaries, using a scoring method to quantify their experiences. They also completed surveys about their upper respiratory symptoms and quality of life at different points: before traveling and four days post-travel.
While we noted that the group taking the placebo experienced more cold episodes, the difference wasn't statistically significant. However, those taking elderberry had a significantly shorter duration of cold days and a lower average symptom score overall, suggesting that elderberry may significantly lessen the impact of colds during air travel.
Further research is essential to validate our findings and to better understand the broader health benefits of elderberry, both physical and mental.
10
Cold symptoms gone
Most Useful Review
It knocked my cold/flu-like symptoms out in three days. This outstanding immune-boosting syrup is my go-to since last winter, when I felt a cold coming on. I experienced mild joint aches, coughing, sneezing, and a low-grade fever. I started taking Sambucol right away and, three days later, all symptoms vanished. The cold/flu never developed further, and I was sold! If I could suggest anything, it would be to make it less sweet. I highly recommend Sambucol and will purchase it again.
Cough
SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
2
Zinc acetate ineffective for cough
Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial.
Most Relevant Research
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
10
Instant cough relief
Most Useful Review
What a relief! This product works exceptionally well. It took my cough away immediately, and the taste is far better than other medicines.
Flu
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.7
USERS' SCORE
Good
Based on 1 Review
8.6
9
Elderberry inhibits H1N1 flu infection
Elderberry flavonoids bind to and prevent H1N1 infection in vitro.
Most Relevant Research
We delved into how elderberry, specifically from the black elderberry fruit, impacts the flu virus, H1N1. Using an innovative technique called Direct Analysis in Real Time Mass Spectrometry (DART TOF-MS), we were able to identify the powerful anti-viral properties of elderberry extract without the need for complicated processes like separation or derivatization.
Our findings revealed that elderberry extract does indeed inhibit H1N1 infection in a lab setting, with an effective concentration (IC50) of 252 micrograms per milliliter. Interestingly, we discovered that flavonoids present in the elderberry bind to H1N1 virions—essentially blocking their ability to infect host cells.
Among the compounds, two key flavonoids emerged: the 5,7,3',4'-tetra-O-methylquercetin and dihydromyricetin. These compounds not only bound to the virus but also effectively prevented infection. Notably, the tetra-O-methylquercetin demonstrated an impressive IC50 of just 0.13 micrograms per milliliter, which is comparable to well-known antiviral medications like Oseltamivir and Amantadine.
In summary, elderberry shows promising potential as a natural remedy against the H1N1 flu, offering a fascinating area for further research and utilization in flu prevention strategies.
Our findings revealed that elderberry extract does indeed inhibit H1N1 infection in a lab setting, with an effective concentration (IC50) of 252 micrograms per milliliter. Interestingly, we discovered that flavonoids present in the elderberry bind to H1N1 virions—essentially blocking their ability to infect host cells.
Among the compounds, two key flavonoids emerged: the 5,7,3',4'-tetra-O-methylquercetin and dihydromyricetin. These compounds not only bound to the virus but also effectively prevented infection. Notably, the tetra-O-methylquercetin demonstrated an impressive IC50 of just 0.13 micrograms per milliliter, which is comparable to well-known antiviral medications like Oseltamivir and Amantadine.
In summary, elderberry shows promising potential as a natural remedy against the H1N1 flu, offering a fascinating area for further research and utilization in flu prevention strategies.
10
Symptoms cleared fast
Most Useful Review
Knocked cold/flu symptoms away in three days! I used it last winter and ordered early for the upcoming season. Initially, I felt a cold coming with mild symptoms, joint aches, coughing, and a low-grade fever. I took Sambucol as soon as I got home, and three days later, all symptoms had vanished. The cold/flu never progressed, and I was sold! The only suggestion is to make it less sweet. I highly recommend Sambucol and will repurchase.
