Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
3 g
1%*
Magnesium (as magnesium malate trihydrate)
425 mg
101%
Sodium
10 mg
<1%
Magnesium Malate Trihydrate
3.75 g
†
Malic Acid (as magnesium malate trihydrate and malic acid)
2.5 g
†
The product is found useful for the following medical conditions
Constipation details
SCIENTIFIC SCORE
Questionable
Based on 22 Researches
6.8
USERS' SCORE
Excellent
Based on 14 Reviews
9.3
9
We explored the effectiveness of magnesium oxide (MgO) as a treatment for chronic constipation using a robust randomized, placebo-controlled trial. Over 28 days, participants received MgO, senna, or a placebo.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
Both MgO and senna significantly improved bowel movement frequency and quality of life compared to placebo. About 68.3% of those using MgO reported symptom improvement, showcasing its potential as an effective osmotic agent alongside a stimulant laxative.
Importantly, there were no severe treatment-related side effects reported during the trial.
10
Pain and constipation relief
Most Useful Review
641 people found this helpful
I have severe myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and fibromyalgia, coping with constant pain. I decided to try magnesium malate, expecting little. However, shortly after taking three pills, I realised I was pain-free for the first time in years! I've been taking six pills daily and experienced significant pain reduction and resolved constipation. This product might be helpful for those with ME/CFS or fibromyalgia. After three weeks, my hair-fall has decreased as well. It's allowed me to engage in activities I couldn't before!
Updated: Mar 2026
Atrial Flutter details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 6 Reviews
8.8
8
Magnesium enhances ibutilide for TAF
We explored how magnesium sulfate influences ibutilide's effectiveness in converting atrial flutter. This randomized, placebo-controlled study included 117 patients with typical (TAF) or atypical atrial flutter (AAF).
Results showed that magnesium significantly enhanced conversion rates in TAF patients—85% with magnesium compared to 59% with placebo. However, for AAF patients, the difference was not significant, with conversion rates at 48% versus 56%. Importantly, magnesium did not impact QT interval durations.
Results showed that magnesium significantly enhanced conversion rates in TAF patients—85% with magnesium compared to 59% with placebo. However, for AAF patients, the difference was not significant, with conversion rates at 48% versus 56%. Importantly, magnesium did not impact QT interval durations.
10
Effective treatment
Most Useful Review
5 people found this helpful
The drug worked for me—my arrhythmia stopped. Fast and convenient!
Updated: Mar 2026
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.8
USERS' SCORE
Good
Based on 6 Reviews
8.7
8
We examined how incorporating fly ash into magnesium phosphate repair mortar (MPM) influences its effectiveness in cold environments. Our investigation revealed that fly ash modifies the microstructure of the MPM, enhancing its performance without affecting the setting time or fluidity significantly.
We discovered that adding 10% to 15% fly ash improves the mechanical strength, adhesion, water resistance, and stability of the mortar. Notably, we found that the curing temperature plays a critical role; as the temperature rises, compressive strength increases, while properties like flexural strength decrease.
Interestingly, even when cured in icy conditions at -20°C or 0°C, MPM with fly ash retains good early strength and strong adhesion properties. This suggests magnesium phosphate repair mortar modified with fly ash is suitable for emergency repairs in cold weather, showcasing its potential for use in challenging environments.
We discovered that adding 10% to 15% fly ash improves the mechanical strength, adhesion, water resistance, and stability of the mortar. Notably, we found that the curing temperature plays a critical role; as the temperature rises, compressive strength increases, while properties like flexural strength decrease.
Interestingly, even when cured in icy conditions at -20°C or 0°C, MPM with fly ash retains good early strength and strong adhesion properties. This suggests magnesium phosphate repair mortar modified with fly ash is suitable for emergency repairs in cold weather, showcasing its potential for use in challenging environments.
9
Prevents colds
Most Useful Review
I'm taking it for corona measures. I heard that Japanese people tend to be deficient in magnesium, so I quickly bought it for my family and myself. I've been using it for a year, and everyone leads a life entirely free from colds and viruses. I also take vitamin D and vitamin C, but I believe this supplement also contributes significantly.
Updated: Apr 2025
Menopause details
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.6
USERS' SCORE
Good
Based on 5 Reviews
8.7
9
We explored the connection between magnesium deficiency and various challenges commonly faced by postmenopausal women, such as chronic pain, memory decline, and mood disorders. Our research specifically focused on how magnesium supplementation can help in alleviating these issues in ovariectomized and aged female mice—modeling the postmenopausal state.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
We administered magnesium-L-threonate to these mice to assess its effects on pain sensitivity, memory function, and emotional behavior through behavioral tests. We found that this treatment not only prevented but also reversed many of the disturbances associated with aging and menopause.
Additionally, we noted significant changes at the molecular level, such as increased levels of inflammatory markers in the brain and spinal cord of untreated mice, which were significantly normalized with magnesium treatment. Notably, low magnesium levels in various body fluids were also addressed by this supplementation, suggesting its potential as a therapeutic approach for menopause-related disorders.
In summary, while estrogen loss during menopause leads to neuroinflammation and related health issues, magnesium supplementation presents a promising option to support postmenopausal health.
9
Symptom relief
Most Useful Review
16 people found this helpful
This product is amazing. I decided to try it based on a newsletter I read. Most adults do not consume enough of this essential nutrient, leading to issues like anxiety and menopausal symptoms. My wife is grappling with menopause-related troubles such as night sweats and restless legs. After 30-60 days of using it, our well-being has markedly improved. I’m sleeping soundly, and my wife is almost symptom-free from her menopause struggles that she had previously encountered. We've shared our positive experiences with everyone we know.
Updated: Apr 2025
Headache details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Good
Based on 18 Reviews
8.6
9
Magnesium aids migraine management
We explored the impact of magnesium on migraine headaches, focusing on its potential benefits based on various studies. Magnesium deficiency is quite common and can arise from different factors, such as not consuming enough through diet or losing more through bodily systems.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
A wealth of research, including case reports and controlled trials, suggests that magnesium supplementation can effectively alleviate migraines, both in the short term and long term. The proposed reasons for this effectiveness range from magnesium's role in preventing spreading cortical depression to its ability to manage oxidative stress and inflammation.
This evidence leads us to consider magnesium not just as a dietary supplement but as an important player in migraine management. Understanding these links helps us contemplate magnesium’s role in prevention and treatment, promising a potential path for those who suffer from this debilitating condition.
10
Miraculous results
Most Useful Review
123 people found this helpful
I have suffered from migraines for 20 years, using various medications. After trying this product, I felt better than I had in years. The very next day, I had no headaches at all. I highly recommend it for those suffering from migraines.
Updated: Apr 2025
Hypertension details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns.
9
Effective hypertension solution
Most Useful Review
68 people found this helpful
I loathed taking my blood pressure medication. Diagnosed with hypertension at 26, I discontinued my meds, causing my pressure to rise. Learning that hypertension can stem from various factors, including being overweight and stress, I began a health journey, losing 14 pounds and altering my diet. Despite these changes, my blood pressure remained high until a friend suggested Magnesium. After purchasing this brand, I took three tablets daily, and now my blood pressure is 109/74, down from 138/100 last week and 121/83 while on prescription meds. This product seems effective for me.
Updated: Apr 2025
Knee Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.9
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.
Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
9
Reduced overall pain
Most Useful Review
I take it for muscle and neuromuscular pain. It helps me combat constant headaches linked to my anxiety, my sleep has improved significantly, and I feel more energetic. My stressful lifestyle and age have made it essential for calcium absorption, greatly alleviating my knee pain. My cramps have also decreased.
Updated: Apr 2026
Leg Cramps details
SCIENTIFIC SCORE
Likely Ineffective
Based on 17 Researches
4.8
USERS' SCORE
Good
Based on 115 Reviews
8.6
9
Magnesium oxide treats leg cramps
We conducted a study to evaluate how effective magnesium oxide monohydrate (MOMH) is in treating nocturnal leg cramps (NLC). This was a randomized, double-blind, placebo-controlled trial involving multiple centers in Ukraine, where participants took either MOMH or a placebo nightly for 60 days.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
Our focus was on measuring the frequency and duration of cramps, the pain they caused, and how they affected sleep quality and overall life satisfaction. We used thorough statistical methods to compare the results between the two groups.
The findings indicated that MOMH is both effective and safe for individuals dealing with NLC. Participants reported improvements in their symptoms, demonstrating that this magnesium supplement can play a helpful role in managing nocturnal leg cramps.
9
Supports muscular system
Most Useful Review
143 people found this helpful
Very good quality magnesium. My husband takes it as recommended by his doctor. He takes three tablets daily, and it supports his muscle system effectively. His nocturnal leg cramps and twitching have disappeared while benefiting his heart.
Updated: Apr 2025
Reflux details
SCIENTIFIC SCORE
Moderately Effective
Based on 11 Researches
8.1
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
We examined the role of magnesium alginate in treating laryngopharyngeal reflux (LPR), which causes symptoms like voice issues, swallowing difficulties, and coughing. In a study involving 100 outpatients, patients were treated with alginate for two months, visiting at the start and then at 15, 30, and 60 days.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
The results were promising, showing a significant reduction in all symptoms assessed. This suggests that magnesium alginate could be a safe and effective alternative for managing LPR, especially for those who cannot fully rely on conventional treatments like proton pump inhibitors.
10
Reflux relieved
Most Useful Review
3 people found this helpful
I experienced reflux, heartburn, and difficulty swallowing due to dysphagia. After using this product for a while, my heartburn and reflux completely disappeared, and my dysphagia improved. I can now swallow pills like Solgar's Calcium Complex and generally eat more freely without the fear of food getting stuck in my oesophagus.
Updated: Apr 2025
Arthritis details
SCIENTIFIC SCORE
Moderately Effective
Based on 17 Researches
8.1
USERS' SCORE
Good
Based on 7 Reviews
8.5
8
Magnesium protects against bone erosion
We delved into the relationship between magnesium levels and gouty arthritis, a condition known for causing painful flare-ups and damaging joint function. Our research focused on measuring serum ionized magnesium levels in a group of 769 patients and assessing how these levels relate to bone erosion, a serious complication of gout.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.
Our findings revealed that patients experiencing bone erosion had significantly lower magnesium levels compared to those without erosion. When we categorized magnesium levels into quartiles, the data showed that those in the lowest quartile (Q1) were more likely to have bone erosion compared to patients in higher quartiles. In fact, the prevalence of erosion in the lowest magnesium group was much higher, illustrating a clear connection.
Through detailed analysis, we concluded that higher levels of serum ionized magnesium may serve as a protective factor against bone erosion in gouty arthritis. This suggests that magnesium supplementation could be a promising strategy for individuals suffering from this debilitating condition, potentially helping to slow down or prevent further joint damage.
9
Pain management success
Most Useful Review
I consistently use this magnesium as it significantly reduces the pain associated with my rheumatoid arthritis.
Updated: Apr 2025
Autoimmune Disorder details
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.4
USERS' SCORE
Good
Based on 5 Reviews
8.5
9
We analyzed how magnesium supplementation affects the biology of rheumatoid arthritis (RA) in mice. By feeding one group a diet rich in magnesium and another a standard diet over 15 days, we examined changes in their tissue responses.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
Our findings revealed that increased magnesium intake may alter gene expression linked to oxidative stress and cellular aging, processes that are significant in RA development. This suggests that magnesium could be beneficial for managing RA and potentially other autoimmune disorders by reducing disease severity and joint damage.
9
Improved recovery
Most Useful Review
39 people found this helpful
A beneficial magnesium supplement! It aids in nervous disorders, sleep issues, and muscle relaxation. I take it regularly, as my body requires extra magnesium, and this brand has worked effectively. Swift absorption and natural composition—definitely buying again!
Updated: Apr 2025
Frozen Shoulder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 5 Reviews
8.5
9
Relief from pain
Most Useful Review
Before I knew it, the stiffness and pain in my shoulders had disappeared. I even find myself falling asleep faster at night. I want to keep using it.
Updated: Apr 2025
Hypothyroidism details
SCIENTIFIC SCORE
Possibly Effective
Based on 9 Researches
7.7
USERS' SCORE
Good
Based on 8 Reviews
8.5
8
We explored the impact of levothyroxine sodium tablets on individuals suffering from hypothyroidism, particularly focusing on its effectiveness for those with Hashimoto thyroiditis (HT). This common condition can lead to a range of complications, including serious kidney and muscle injuries, as well as issues with cholesterol and other lipids.
In our examination, we described a specific case involving a 52-year-old woman diagnosed with HT. She faced several health challenges, such as kidney and muscle injuries alongside abnormalities in her lipid profiles. After beginning treatment with levothyroxine, we closely monitored her progress through regular assessments of serum creatinine, creatine kinase, and various cholesterol levels.
Over a two-month treatment period, we observed promising results. The patient experienced significant improvements, with her creatine kinase levels returning to normal. Although her serum creatinine level remained slightly elevated, her kidney function showed restoration, and other lipid levels improved significantly. By alleviating these complications, levothyroxine helped address many of her HT-related symptoms, highlighting its benefits in treating severe hypothyroidism manifestations.
In our examination, we described a specific case involving a 52-year-old woman diagnosed with HT. She faced several health challenges, such as kidney and muscle injuries alongside abnormalities in her lipid profiles. After beginning treatment with levothyroxine, we closely monitored her progress through regular assessments of serum creatinine, creatine kinase, and various cholesterol levels.
Over a two-month treatment period, we observed promising results. The patient experienced significant improvements, with her creatine kinase levels returning to normal. Although her serum creatinine level remained slightly elevated, her kidney function showed restoration, and other lipid levels improved significantly. By alleviating these complications, levothyroxine helped address many of her HT-related symptoms, highlighting its benefits in treating severe hypothyroidism manifestations.
9
Energy boost experienced
Most Useful Review
21 people found this helpful
Gave me my energy back! Having hypothyroidism and Hashimoto's disease left me exhausted. After researching magnesium's benefits, I decided to try it. Within a week, I noticed a significant increase in energy levels, even hiking 7 miles in a day! Previously, I struggled to get out of bed, but if I forget a dose, the sluggishness returns immediately. This product has genuinely changed my life; if you suffer from hypothyroidism, give it a try!
Updated: Apr 2025
Multiple Sclerosis details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 3 Reviews
8.5
8
We investigated the potential benefits of magnesium in the form of a new compound, magnesium biotin (MgB), on remyelination in rats with induced demyelination. This is particularly relevant for conditions like multiple sclerosis (MS), where demyelination plays a critical role in disease progression. Through our study, we compared MgB's effects to those of standard biotin.
Our findings revealed that MgB significantly enhanced the remyelination process compared to biotin alone. Both treatments showed a dose-dependent improvement in spatial memory, indicating benefits for cognitive functions. Additionally, MgB treatment led to reduced levels of inflammatory proteins, an effect that was more pronounced at higher doses.
Notably, we discovered that MgB helped restore important proteins involved in neuronal function and transmission, such as Synapsin-1 and PSD-95, which are crucial for healthy brain functioning. We also observed an increase in beneficial brain-derived factors and a notable reduction in markers of reactive gliosis, which suggests a reduction in harmful inflammation.
The evidence indicates that combining magnesium with biotin could provide a more effective treatment strategy for promoting myelin repair in demyelination-driven conditions like MS. Our results support the potential for further research into using MgB in clinical settings for MS patients.
Our findings revealed that MgB significantly enhanced the remyelination process compared to biotin alone. Both treatments showed a dose-dependent improvement in spatial memory, indicating benefits for cognitive functions. Additionally, MgB treatment led to reduced levels of inflammatory proteins, an effect that was more pronounced at higher doses.
Notably, we discovered that MgB helped restore important proteins involved in neuronal function and transmission, such as Synapsin-1 and PSD-95, which are crucial for healthy brain functioning. We also observed an increase in beneficial brain-derived factors and a notable reduction in markers of reactive gliosis, which suggests a reduction in harmful inflammation.
The evidence indicates that combining magnesium with biotin could provide a more effective treatment strategy for promoting myelin repair in demyelination-driven conditions like MS. Our results support the potential for further research into using MgB in clinical settings for MS patients.
9
Migraine relief
Most Useful Review
25 people found this helpful
The migraine has resolved! I previously took magnesium aspartate, but due to its neurotoxic effects, I switched to magnesium malate, taking it several times a day. Alongside magnesium chloride baths, transdermal magnesium oil, and sublingual bitter, I suffered from severe migraines for years. Now, I no longer require painkillers. It turns out I was deficient in magnesium.
Updated: Apr 2025
Anxiety details
SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.9
USERS' SCORE
Good
Based on 15 Reviews
8.4
8
Magnesium treats anxiety in MS
We aimed to understand the impact of nanoparticulate magnesium hydride (MgH) on anxiety and depression associated with multiple sclerosis (MS). Our exploration involved studying how MgH affects mood disorders in a model we designed, specifically using experimental autoimmune encephalomyelitis (EAE) mice.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
We discovered that MgH treatment significantly alleviated anxiety and depression-like behaviors in these mice. Not only did MgH help improve their mood, but it also reduced overall disease severity and inflammatory damage within the central nervous system.
Importantly, our findings suggest that MgH could be working by promoting healthier microglial activity. It appears to encourage the beneficial M2 polarization while inhibiting the harmful M1 polarization, alongside reducing oxidative stress. This mechanism offers a glimpse into how magnesium might truly enhance well-being for those dealing with MS-related psychiatric issues.
In summary, our research indicates that nanoparticulate MgH holds promise as a non-toxic and effective treatment option for anxiety and depression in people suffering from MS, showcasing a potential breakthrough in managing these debilitating conditions.
9
Miraculous results
Most Useful Review
16 people found this helpful
This stuff is amazing! I decided to try this product after reading about nutrient deficiencies. My wife and I are health conscious and prone to anxiety. After 30-60 days, I sleep soundly and feel calmer, while my wife’s menopause symptoms have significantly improved. We've been raving about the incredible results we've experienced!
Updated: Apr 2025
Athlete’s Foot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
Pain relief
Most Useful Review
2 people found this helpful
It’s fantastic! This product alleviates body aches, particularly in the soles of my feet. I highly recommend it to anyone dealing with similar issues.
Updated: Apr 2025
Cardiovascular Disease details
SCIENTIFIC SCORE
Questionable
Based on 12 Researches
6.8
USERS' SCORE
Good
Based on 3 Reviews
8.4
8
Magnesium's impact on heart health
We examined the connection between dietary magnesium and cardiovascular disease, focusing on how magnesium intake or serum levels relate to heart health. Over the last couple of decades, numerous studies have shown that low magnesium levels are associated with several heart-related issues, including high blood pressure, heart attacks, and even heart failure.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
Our insights reveal that even mild or moderate magnesium deficiencies can trigger physiological and metabolic changes that may heighten cardiovascular risks. When magnesium levels are insufficient, we see a rise in inflammation, oxidative stress, and issues with how fats are processed in the body, which can lead to serious heart problems.
Furthermore, we noted that many individuals often consume less magnesium than what is recommended, particularly those who do not regularly eat whole grains, legumes, or green vegetables. This widespread lack of magnesium is concerning, as it could be a significant factor influencing heart disease in the general population.
9
Muscle twitches diminished
Most Useful Review
10 people found this helpful
I bought this product to aid with the muscle twitches associated with chronic Lyme disease. Within a week, the twitches have almost disappeared. Good product, good price.
Updated: Apr 2025
Cholecystitis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.4
7.5
Effective for nerves
Most Useful Review
5 people found this helpful
This is a long-time staple for me. It has performed wonders for my nerves and IBS-C symptoms. I can't recommend it enough. It's best taken before sleep after your last meal, but it can be a bit harsh on an empty stomach due to the malic acid. Unlike other magnesium formulations, magnesium malate does not have a laxative effect at moderate doses, specifically one tablet per day. If you have constipation issues, this supplement will significantly aid in normalising bowel movements. Additionally, the malic acid is excellent for cleaning the gallbladder, reducing the risk of gallstones with regular use. Overall, this is a fantastic supplement that I have been using for 10 years; moderation is key.
Updated: Apr 2025
Dizziness details
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.8
USERS' SCORE
Good
Based on 2 Reviews
8.4
9
Magnesium deficiency reverses dizziness and ataxia successfully
A 68-year-old patient experienced unexplained dizziness, poor balance, and abnormal eye movements that stumped doctors despite extensive brain imaging and testing. The breakthrough came when doctors discovered severe magnesium deficiency caused by long-term use of proton pump inhibitor medications combined with a stomach infection. Once the magnesium was replaced through supplementation, the patient's symptoms improved.
This case highlights an important but often-missed cause of dizziness and balance problems. Magnesium deficiency can produce significant neurological symptoms without showing up on standard MRI scans, making diagnosis tricky. For patients experiencing dizziness along with digestive issues or taking certain common medications, magnesium testing should be a standard part of the evaluation to catch this treatable condition early.
This case highlights an important but often-missed cause of dizziness and balance problems. Magnesium deficiency can produce significant neurological symptoms without showing up on standard MRI scans, making diagnosis tricky. For patients experiencing dizziness along with digestive issues or taking certain common medications, magnesium testing should be a standard part of the evaluation to catch this treatable condition early.
9
Improved wellbeing
Most Useful Review
Constant weakness and fatigue have vanished! My work is quite manual, leading to significant sweating, yet I only consumed water without restoring minerals or using isotonic drinks, which left me depleted. For years I felt unwell, but recently the weakness and fatigue worsened, alongside poor sleep. I occasionally experienced dizziness, making gym attendance nearly impossible. It seemed like my heart lacked the strength to beat. Fortunately, this supplement replenished my magnesium levels, and I noticed nearly immediate improvement. Within weeks, I felt nearly normal again! My sleep quality has also enhanced, and I even started dreaming again, which reflects my improved rest! Even kidney pain disappeared, likely due to magnesium dissolving stones as I've seen in videos. I'm currently taking it with MSM and excitedly awaiting additional supplements to boost my health further.
Updated: Apr 2026
Flu details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 7 Reviews
8.4
7
We explored how magnesium affects our immune response, particularly in relation to fighting off influenza. By examining how magnesium levels influence T cell function, we noticed that lower levels of magnesium in the body could hinder the T cell receptor (TCR) activation process. This is significant because TCR activation is crucial for mounting an effective immune response against viruses like influenza.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
Our findings revealed that insufficient magnesium decreases the activation of important immune cells, specifically CD8 T cells, which are vital for responding to infections. This was further demonstrated in mice where reduced serum magnesium concentrations led to weaker immune responses and more severe illness from influenza A virus.
Overall, we observed that magnesium not only serves as an essential cofactor in cellular processes but also plays a direct role in maintaining strong immune function. Ensuring an adequate intake of magnesium is therefore important for enhancing our ability to combat viral infections effectively.
9
Joint pain lessened
Most Useful Review
14 people found this helpful
After a severe reaction to Levofloxacin, a fluoroquinolone antibiotic, I became nearly incapable of standing or walking. Others recommended this supplement, and it significantly improved my symptoms, resulting in less joint pain and muscle tearing. The difference is striking since I began taking it.
Updated: Apr 2025
Migraine details
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
USERS' SCORE
Good
Based on 13 Reviews
8.4
9
Magnesium reduces migraine symptoms
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.
We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
9
Miraculous effects
Most Useful Review
123 people found this helpful
After suffering from migraines for 20 years and trying various medications that only masked symptoms, I discovered magnesium. Following severe dehydration and a debilitating migraine, I decided to try magnesium. The improvement has been miraculous, resulting in no headaches for over a month. I highly recommend it for those suffering from migraines.
Updated: Apr 2025
Osteoporosis details
SCIENTIFIC SCORE
Moderately Effective
Based on 19 Researches
8.2
USERS' SCORE
Good
Based on 3 Reviews
8.4
9
We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
9
Provides relief
Most Useful Review
My mother suffers from osteoporosis, along with issues with her bones and muscles. Once she started taking this vitamin, it provided her with relief, and she refuses to stop using it.
Updated: Apr 2025
Allergies details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 3 Reviews
8.3
8
Magnesium enhances postoperative recovery
We conducted a study to see how magnesium sulfate could influence recovery after total knee arthroplasty in older patients. Using a double-blind, randomized control design, 148 patients were split into two groups: one received magnesium sulfate while the other got saline.
We found that magnesium sulfate not only reduced early postoperative pain but also enhanced the quality of recovery. This suggests that incorporating magnesium into pain management could be beneficial for older adults undergoing knee surgery, improving their overall recovery experience.
We found that magnesium sulfate not only reduced early postoperative pain but also enhanced the quality of recovery. This suggests that incorporating magnesium into pain management could be beneficial for older adults undergoing knee surgery, improving their overall recovery experience.
9
Effective for allergies
Most Useful Review
10 people found this helpful
Best magnesium. This is the best magnesium I've ever tried. I have tested 8 or 9 different brands and always return to this one. Malate seems to be the most effective for me as it supports my gallbladder. It helps with my allergies, anxiety, fatigue, and stress resilience. Within 2-3 hours of the recommended dose, I feel calmer, more grounded, and my breathing is more open and relaxed. Highly recommend and am grateful for such a wonderful supplement.
Updated: Apr 2025
Blood Clot details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Good
Based on 9 Reviews
8.3
8
Magnesium scaffold shows promising results
We investigated the clinical safety and performance of a new magnesium scaffold known as DREAMS 3G. This innovative treatment aims to match the effectiveness of drug-eluting stents in coronary interventions.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
10
Post-meal pressure control
Most Useful Review
11 people found this helpful
After each meal, I would experience low blood pressure and nearly faint. However, after taking eight magnesium tablets before meals, my postprandial low blood pressure ceased completely from that day on. It is remarkably different from the inferior Japanese magnesium filled with additives.
Updated: Mar 2026
Gastritis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.3
9
No side effects
Most Useful Review
Great magnesium! Malate for energy! I have it for breakfast with food and for lunch. This truly provides a lot of energy, especially from November to April when I usually feel sluggish, but this gives me plenty of strength! It's a good preparation that does not irritate my gastrointestinal tract. With my gastritis, I experienced no adverse effects!
Updated: Apr 2025
Sleep Apnea details
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 96 Reviews
8.3
7
We aimed to uncover the relationship between magnesium levels and sleep quality, particularly focusing on sleep apnea. Our study analyzed data from a large group of adults aged 20 and older, using a well-structured method to assess magnesium levels and the prevalence of sleep issues.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
We found a notable connection between lower magnesium levels, measured as the magnesium depletion score (MDS), and the likelihood of experiencing sleep apnea. Specifically, individuals with higher MDS levels were significantly more likely to report sleep apnea, showing over three times the odds compared to those with adequate magnesium levels.
Interestingly, our research did not link magnesium deficiency to other sleep problems like insomnia or restless legs syndrome, suggesting a more complex relationship with sleep apnea alone. Additionally, we noticed that older adults with depressive symptoms showed a tendency toward excessive sleep rather than insufficient sleep.
While our findings highlight the association between magnesium deficiency and sleep apnea, they also point towards the potential of adequate magnesium intake in reducing this risk. This emphasizes the importance of maintaining proper magnesium levels for better sleep quality, especially in those at higher risk for sleep apnea.
9
Positive overall effects
Most Useful Review
292 people found this helpful
This is an excellent magnesium malate. I appreciated it for several reasons: the price, pleasant taste, product quality, and excellent results. It positively affects my muscles, joints, and sleep. The packaging is convenient, and it contains beneficial ingredients and minerals. I highly recommend this wonderful product; it fully meets my expectations.
Updated: Mar 2026
Swollen Lymph Nodes details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 9 Reviews
8.3
9
Quick swelling relief
Most Useful Review
6 people found this helpful
A super remedy, especially for pregnant women. I took it on the advice of a nutritionist friend who is pregnant. She is very pleased as the swelling passed in a week, and her health improved. I also ordered the same magnesium and look forward to trying it myself.
Updated: Apr 2025
Chronic Fatigue Syndrome details
SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Good
Based on 72 Reviews
8.2
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
9
Reduced pain significantly
Most Useful Review
641 people found this helpful
This product has greatly alleviated my pain and stiffness associated with severe myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia. I didn't expect it to help much, but within 20 minutes of taking a large dose, I realised I was no longer limping or in pain. I'm now taking six pills a day and experiencing much less pain. This supplement has also resolved my chronic constipation. I advise anyone suffering from ME/CFS or fibromyalgia to give it a try, as it might help you too.
Updated: Mar 2026
Diabetes details
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
USERS' SCORE
Good
Based on 5 Reviews
8.2
8
Magnesium intake benefits diabetes patients
We investigated the link between dietary magnesium intake and the risk of heart disease and death in over 149,000 individuals, including those with type 2 diabetes. Through careful analysis over a median of 12 years, we found that higher magnesium intake was associated with significantly lower risks of heart disease and mortality in individuals with diabetes.
However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.
However, this benefit wasn't seen in those without diabetes. Our findings highlight the potential for magnesium to play a crucial role in health management for people living with type 2 diabetes, signaling the need for tailored dietary guidance.
9
Relieves neuropathic pain
Most Useful Review
Pain from neuropathy due to diabetes was unbearable for my uncle, who struggled to walk. Magnesium became a lifesaver, alleviating his leg pain effectively.
Updated: Mar 2026
Adrenal Gland Disorder details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 45 Reviews
8.1
7.5
Impressive results
Most Useful Review
5 people found this helpful
I previously used UltraMag magnesium before switching to pure magnesium malate, which I chose for its indication for adrenal exhaustion. Adults are advised to consume at least 400 mg per day, and I’m currently taking 400 mg regularly. After experiencing a laxative effect for not adhering to the recommended dosage, I now follow the instructions carefully. This supplement lasts four months; I find it aids in sleep and stress resilience. Good health and clarity of mind to all!
Updated: Apr 2025
Back Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
USERS' SCORE
Good
Based on 11 Reviews
8.1
9.5
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
9
Knee pain mitigated.
Most Useful Review
136 people found this helpful
After battling Lyme disease, I faced knee pain and muscle stiffness. I turned to Magnesium Malate during a particularly difficult night and found relief quickly. Now, after three weeks, I’m experiencing a significant reduction in pain and an improvement in my energy levels. This supplement has had a miraculous effect on my overall wellbeing.
Updated: Apr 2025
Bone Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 8 Reviews
8.1
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7.5
Reduced muscle pain
Most Useful Review
7 people found this helpful
1250mg of magnesium malate has made a noticeable difference for me. While it may take weeks or months to fully evaluate its effectiveness, I can confirm that my numerous muscle pains have become bearable. Despite relying on over a dozen prescription medications daily, nothing has alleviated my pain as much as magnesium. Even my arthritis in the knees has improved significantly. I have spent over $2,000 on ineffective injections, yet this supplement has no side effects or adverse symptoms, only positive feelings. For now, it deserves a score of 4, possibly rising to 5.
Updated: Apr 2025
Chronic Cough details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 9 Reviews
8.1
9
Cramps alleviated
Most Useful Review
11 people found this helpful
After experiencing morning cramps, I purchased magnesium and no longer suffer from leg cramps. It’s effective after muscle training, reducing fatigue. If I take it on an empty stomach, it causes discomfort; however, I've learned that taking it post-meal improves digestion. It's also suitable for those with chronic fatigue syndrome and enhances energy storage.
Updated: Apr 2026
Depression details
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Good
Based on 6 Reviews
8.1
9
We conducted a systematic review and meta-analysis exploring how dietary magnesium (Mg) intake connects with depression among adults. By reviewing data from over 63,000 individuals, we found that those with the highest magnesium intake had a 34% lower chance of experiencing depression compared to those with the lowest intake.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
Furthermore, our analysis indicated that every increase of 100 mg per day in magnesium intake was linked to a 7% reduced risk of depression. These findings suggest that increasing dietary magnesium could play a valuable role in lowering depression risk.
10
Helps with depression
Most Useful Review
1 people found this helpful
Great for depression. It truly assists with my depression. I'm utterly in love with its excellent qualities.
Updated: Apr 2025
Nausea details
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 4 Reviews
8.1
8
We conducted a study to discover how magnesium sulfate affects nausea during orthognathic surgery. In this research, we divided 75 adult patients into two groups: one group received magnesium sulfate, while the other received a placebo saline solution.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
We discovered that those who received magnesium experienced significantly less postoperative nausea and vomiting (PONV) compared to the control group. Specifically, at two hours post-surgery, patients in the magnesium group reported less severe PONV.
Additionally, this group also had lower requirements for remifentanil, a pain reliever, indicating that magnesium not only helps with nausea but may also play a role in overall pain management during recovery. The magnesium levels in the blood after surgery were notably higher in the magnesium group, further supporting its effectiveness.
This research suggests that incorporating magnesium sulfate into treatment protocols during orthognathic surgeries can greatly enhance patient comfort by minimizing nausea and improving pain control.
9
No nausea
Most Useful Review
2 people found this helpful
Excellent supplement! This is the only form of magnesium that does not cause nausea, is reasonably priced, and provides a high mg per serving. A single tablet a day meets my daily needs effectively. I highly recommend this product.
Updated: Apr 2025
Pelvic Pain details
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.3
USERS' SCORE
Good
Based on 75 Reviews
8.1
8
We evaluated how magnesium pidolate impacts primary dysmenorrhea in 30 young women. Over six menstrual cycles, we tracked their pain levels using a visual scale. Initially, no treatment was given, and subsequently, magnesium was administered just before menstruation.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
The first day of menstrual pain showed a notable decrease with magnesium treatment, especially from the first to the sixth cycle. While there were some improvements on days two and three, those weren't statistically significant. Importantly, no side effects were reported, suggesting magnesium can be a reliable option for managing menstrual pain.
9
Increased energy levels
Most Useful Review
95 people found this helpful
Still works after 20 years. Shortly after I was diagnosed with fibromyalgia over 20 years ago, I began using Magnesium Malate to boost my energy levels and alleviate the pain in my soft tissues. I don't know what I would have done without it. It has been crucial in allowing me to get off the sofa each day and truly live my life. The great part is you see results after only two or three days of use, so you know if it's going to work for you without waiting a month. It has definitely worked for me and continues to do so.
Updated: Apr 2025
Stroke details
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.5
USERS' SCORE
Good
Based on 2 Reviews
8.1
9
We embarked on an intriguing exploration of how magnesium might help during cerebral ischemia, particularly after an acute stroke. The study set out to determine the potential benefits of a biodegradable neuroprotective stent that releases magnesium into the bloodstream, targeting areas impacted by reperfusion injury.
To do this, we first looked at how pure magnesium affected neuron cells that had undergone oxygen-glucose deprivation and reoxygenation. Encouragingly, we found that the magnesium could indeed protect these cells from injury.
Building on this, we then tested out a magnesium wire in the carotid artery of rats, mimicking the human experience of stroke. The results indicated that this method successfully helped reduce behavioral issues, neural damage, and even blood-brain barrier disruption in the rats following a known stroke model.
In conclusion, magnesium-based implants may represent a promising local treatment option for alleviating the damage caused by strokes, bolstering support for using magnesium in neuroprotection.
To do this, we first looked at how pure magnesium affected neuron cells that had undergone oxygen-glucose deprivation and reoxygenation. Encouragingly, we found that the magnesium could indeed protect these cells from injury.
Building on this, we then tested out a magnesium wire in the carotid artery of rats, mimicking the human experience of stroke. The results indicated that this method successfully helped reduce behavioral issues, neural damage, and even blood-brain barrier disruption in the rats following a known stroke model.
In conclusion, magnesium-based implants may represent a promising local treatment option for alleviating the damage caused by strokes, bolstering support for using magnesium in neuroprotection.
7.5
Normalised nerves
Most Useful Review
I don't know how many times I've ordered this magnesium, it must be at least ten. I also bought it for older colleagues with vascular issues, who said it's the best, and they truly felt its effect. There are no side effects, and I've noticed more energy and normalised nerves. My sister's convulsions have stopped, and my father, following his stroke, now prefers this alongside his other medications, completely excluding pharmaceuticals. Remember, stress depletes magnesium quickly. I highly recommend it.
Updated: Apr 2025
Adenoiditis details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 3 Reviews
8
9
Works very well
Most Useful Review
2 people found this helpful
I love this magnesium. It works exceptionally well. The tablets are large but coated to slide down easily. However, I would prefer it in a capsule or powder form, especially for patients who struggle with tablets, as it can easily be added to food or drink. The product itself is very effective.
Updated: Apr 2025
Brain Tumor details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.2
USERS' SCORE
Good
Based on 7 Reviews
8
7
Magnesium reduces brain injury markers
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
9
Improved sleep quality
Most Useful Review
5 people found this helpful
This magnesium malate is excellent value for money. It normalises cell growth, is quickly absorbed, and enhances brain health, alleviating insomnia, headaches, and depression. I typically take it before bed, and it improves both my sleep and overall well-being. Although the jar is secure, it’s kept out of children's reach. I recommend this supplement highly!
Updated: Apr 2025
Fibromyalgia details
SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.7
USERS' SCORE
Good
Based on 20 Reviews
8
7
We conducted a randomized, controlled, double-blind study to determine the effects of magnesium on fibromyalgia symptoms. Our findings showed that magnesium supplementation did not lead to a significant reduction in overall stress levels compared to placebo.
However, we did find that magnesium significantly reduced mild to moderate stress and pain severity among participants. These results suggest that including magnesium in treatment could help alleviate some of the burdens fibromyalgia patients face.
This research indicates further exploration of magnesium’s potential should take place in larger studies.
However, we did find that magnesium significantly reduced mild to moderate stress and pain severity among participants. These results suggest that including magnesium in treatment could help alleviate some of the burdens fibromyalgia patients face.
This research indicates further exploration of magnesium’s potential should take place in larger studies.
9
Essential priority
Most Useful Review
15 people found this helpful
I have suffered from fibromyalgia for most of my adult life. Magnesium Malate was recommended by my former family doctor, who was knowledgeable about fibro. When I miss a dose, I notice changes in my muscle function, making Mag Malate essential for me.
Updated: Mar 2026
Indigestion details
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 3 Reviews
8
9
We explored how magnesium treatment impacts indigestion and metabolic disturbances in cows, comparing two herds with issues to a control group. Our observations showed that while the method of applying magnesium powder on pastures was ineffective, supplementing with magnesium oxide in feed was quite beneficial. Administering 50 grams per cow per day for 14 days before grazing effectively prevented hypomagnesemia. However, signs of metabolic issues and alkaline indigestion were still more pronounced in troubled herds compared to the control, indicating the challenges that persist despite treatment.
9
Gradual intake advised
Most Useful Review
The initial intake of this magnesium requires some adjustment. I recommend starting slowly; perhaps begin with only one-sixth of the dosage and gradually increase to the full dosage over a few weeks. This is my fourth order, and I have found that malic acid effectively alleviates my indigestion.
Updated: Mar 2026
Irritable Bowel Syndrome details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 3 Reviews
7.9
8
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
7.5
Bowel improvement
Most Useful Review
Reduces muscle pain and enhances bowel movements. I highly recommend it.
Updated: Apr 2025
Heart Attack details
SCIENTIFIC SCORE
Questionable
Based on 23 Researches
6.6
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.8
9
We explored the potential of magnesium implantation as a new approach to combat heart attacks, specifically myocardial infarction (MI). Our research centered on using magnesium slices implanted under the skin of rats to generate hydrogen gas continuously. This method could ensure a greater and longer-lasting concentration of hydrogen directly reaching the heart, which is crucial for its therapeutic effects.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
Through our study, we measured how effectively the magnesium produced hydrogen and evaluated its safety. The results were promising; we observed that magnesium implantation not only improved cardiac function in rats suffering from MI, but also played a role in eliminating harmful free radicals from mitochondrial dysfunction. Furthermore, it helped reduce cell death in heart muscle cells, which is a common consequence of heart attacks.
Compared to traditional hydrogen inhalation, which has limitations in delivering sufficient doses over time, magnesium implantation proved to be a superior method. Overall, our findings pave the way for innovative treatments that could enhance recovery after heart attacks by harnessing the unique properties of magnesium for hydrogen production.
7.5
Panic attack reduction
Most Useful Review
106 people found this helpful
Magnesium has transformed my life. After an unsettling heart episode, I struggled with anxiety and panic attacks, fearing the worst. I adopted a healthier lifestyle and avoided medications but was still feeling the strain. After starting magnesium malate, I noticed improvements within three days—my anxiety lessened significantly, I no longer face panic attacks, and I have better sleep. I'm now determined to regain my strength and health.
Updated: Apr 2025
Bloating details
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.5
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.5
8
We explored the impact of magnesium supplementation on bloating as part of a larger study examining premenstrual symptoms. In our randomized, double-blind, placebo-controlled design, we administered a daily dose of 200 mg of magnesium (as MgO) to participants over the course of two menstrual cycles. Each volunteer kept track of their symptoms using a detailed diary with twenty-two items.
Initially, we found no difference in premenstrual symptoms between the magnesium and placebo groups during the first month. However, during the second month, participants taking magnesium experienced a notable decrease in bloating and hydration-related symptoms such as weight gain and breast tenderness. This reduction in symptoms was statistically significant, indicating that magnesium can indeed alleviate certain premenstrual symptoms like bloating.
Our findings suggest that magnesium supplementation, particularly in the context of fluid retention and bloating, could be beneficial for women experiencing these discomforts during their menstrual cycle. Overall, this study opens the door to considering magnesium as an effective remedy for mild premenstrual bloating.
Initially, we found no difference in premenstrual symptoms between the magnesium and placebo groups during the first month. However, during the second month, participants taking magnesium experienced a notable decrease in bloating and hydration-related symptoms such as weight gain and breast tenderness. This reduction in symptoms was statistically significant, indicating that magnesium can indeed alleviate certain premenstrual symptoms like bloating.
Our findings suggest that magnesium supplementation, particularly in the context of fluid retention and bloating, could be beneficial for women experiencing these discomforts during their menstrual cycle. Overall, this study opens the door to considering magnesium as an effective remedy for mild premenstrual bloating.
9
Reduced bloating
Most Useful Review
Great! I feel much better after taking these; I am less bloated and have more energy!
Updated: Apr 2025
Premenstrual Syndrome details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Moderately Good
Based on 31 Reviews
7.5
7.5
Relieves muscle tension
Most Useful Review
5 people found this helpful
The best magnesium I've found! It effectively relieves muscle tension and replenishes magnesium levels, improves sleep quality, and alleviates symptoms of PMS. It positively impacts overall health, so I recommend a morning and evening dose for best results.
Updated: Apr 2026
Heartburn details
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.5
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.2
9
We explored the impact of a new treatment, Marial®, on patients suffering from gastroesophageal reflux disease (GERD). In a large survey involving 56 gastroenterological offices across Italy, patients were treated with either proton pump inhibitors (PPIs), a combination of PPIs and an additional remedy, or the Marial® formulation containing magnesium alginate. The results showed that both Marial® and the combination therapy significantly reduced heartburn symptoms, with Marial® proving to be more effective than the combination. Overall, patients reported a marked improvement in their GERD-related symptoms.
9
No heartburn effects
Most Useful Review
I appreciate this product as it does not cause heartburn and is easy to swallow, making it a preferred choice for me.
Updated: Mar 2026
Diarrhea details
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.6
USERS' SCORE
Moderately Good
Based on 11 Reviews
7
9.5
We explored the impact of magnesium on secretory diarrhea, particularly in the context of cholera, a significant global health issue. The focus was on understanding how magnesium, often overlooked, could serve as an effective treatment option. In our study, we found that increasing levels of magnesium can significantly inhibit chloride secretion in intestinal cells, which is crucial during episodes of diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
We observed that magnesium, at concentrations typically seen in stool, reduced this secretory process by a remarkable 65%. This effect primarily occurs through a specific receptor in the intestinal cells known as the calcium-sensing receptor (CaSR). Interestingly, we noted that magnesium also counteracted Cl- secretion triggered by cholera toxin and other enterotoxins by about 50%.
Using mouse models, we saw that administering magnesium effectively decreased fluid loss associated with cholera by 40%. In a model mimicking the intestinal environment during cholera, adding magnesium not only curbed fluid secretion but also reversed it, promoting absorption instead. Given that patients suffering from cholera often have negligible magnesium levels in their stool, our findings suggest that oral magnesium supplementation could be a simple but effective therapeutic strategy for managing cholera and potentially other forms of secretory diarrhea.
7.5
Improved anxiety significantly
Most Useful Review
6 people found this helpful
I didn't believe this would work at first. Regular magnesium caused me diarrhoea while I aimed to alleviate anxiety and constipation. After starting with one pill I felt less anxious and gradually increased the dosage. Now, it’s incredible; I've been using the bathroom regularly and my anxiety is improving. This product has made a significant difference for me.
Updated: Apr 2025
Insomnia details
SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.4
USERS' SCORE
Medium or Average
Based on 13 Reviews
6.5
9
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
7.5
Experimental relief
Most Useful Review
27 people found this helpful
I began experimenting with magnesium after reading about its neurological and cardiological benefits. After four months, I've found this product particularly beneficial for my insomnia and restless legs. I experienced immediate relief from the unpleasant sensations that previously disrupted my sleep. I'm not sleeping perfectly yet, but my episodes of restless legs have ceased, and I rest much more soundly.
Updated: Apr 2025
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