Products best matching Alzheimer

Milk Thistle Silymarin

9
Silibinin reduces Alzheimer's neuroinflammation
We explored how silibinin, derived from Silybum marianum, may help combat Alzheimer's disease, particularly the sporadic form that affects most patients. Using a model involving murine hippocampal neurons and rats, we found that silibinin improves cell survival and reduces cognitive decline linked to Alzheimer's.

Those treated with silibinin displayed a notable decrease in neuroinflammation and oxidative stress—two key contributors to Alzheimer’s. It achieves this by regulating proteins involved in cell death. However, it remains essential to continue research to fully understand its benefits and mechanisms before considering practical applications.
9
Neuroprotective properties
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92 people found this helpful
Since ancient times, milk thistle has been used for neurological diseases. Today, it treats conditions like Parkinson's and Alzheimer’s. Its anti-inflammatory and antioxidant properties may provide neuroprotective effects.

Turmeric Curcumin

9
Turmeric aids Alzheimer’s treatment
We explored the effects of Curcuma wenyujin extract, commonly known as turmeric, on Alzheimer's disease (AD) using a methodical approach. The research centered on how this traditional medicine could potentially improve cognitive function and combat the negative processes associated with AD.

To investigate these effects, mice that were induced with amyloid-beta (Aβ) to mimic AD received daily treatments with turmeric extracts for three weeks. We assessed their cognitive abilities through various behavioral tests and employed proteomics analysis to identify the therapeutic targets impacted by the extract.

Our findings revealed that the ethyl acetate fraction of turmeric showed the most promise in treating Alzheimer's. The treatment not only enhanced memory and cognition in the mice but also contributed to better neuronal health and reduced amyloid accumulation in the brain. Importantly, we observed that turmeric helped lower inflammation and promoted processes like mitophagy, key for cell health, through the activation of the PINK1/Parkin pathway.
9
Alzheimer prevention
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A highly recommended product! This well-known brand provides quality ingredients, offering a capsule a day that potentially helps prevent Alzheimer's and cancer.

Inositol

7
Inositol improves cognition in females
Our investigation focuses on the role of inositol supplementation in enhancing cognitive function in mice, particularly in the context of the ApoE2 genetic background, which is thought to provide some protective effects against Alzheimer's disease.

We discovered that aged female mice carrying the ApoE2 genotype exhibited a decline in spatial cognitive abilities compared to their ApoE3 counterparts. This decline was linked to impaired insulin signaling within the hippocampus, a brain region crucial for memory and learning.

Upon looking closer, we found that the ApoE2 females had lower levels of inositol, a compound that plays a role in insulin signaling. Encouragingly, when these mice received inositol supplementation, we observed improvements in insulin signaling, better glucose tolerance, and enhanced cognitive functions.

Interestingly, we did not find similar effects in male mice, highlighting that the benefits of inositol may be sex-specific, particularly for aged females. This research adds an intriguing chapter to our understanding of how certain genetic factors interact with metabolic processes to influence cognitive health, pointing to inositol as a potential avenue for therapeutic intervention.
9
Combats memory loss
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Choline is crucial for human growth, development, and various bodily functions. Highest in dairy and meat, it assists nerve cells in communication. Recent studies suggest choline may combat Alzheimer's disease and improve memory. It also maintains cell structure and liver health, vital for a healthy nervous system and brain development.

Magnesium

7
Magnesium may protect cognition
We set out to understand how magnesium influences cognitive decline, especially in those experiencing olfactory impairment, using data from the National Health and Nutrition Examination Survey (NHANES) 2013-2014.

Our analysis included nearly 1,400 older individuals, revealing that 22.98% had olfactory impairments. Interestingly, we discovered that higher magnesium intake correlated with a reduced risk of cognitive decline, with a reported beta value of -0.21. This means that those consuming more magnesium showed better cognitive performance.

When looking specifically at participants with olfactory impairment, we noted that those with a high magnesium intake had a significantly lower risk of cognitive decline compared to those with a low intake. This protective effect was particularly evident among women, individuals with diabetes, and those without cardiovascular issues or depression.

These findings suggest that adequate magnesium intake might support cognitive function among older adults facing olfactory challenges. However, we recognize the need for larger, more in-depth studies to confirm these results definitively.
9
Alleviates symptoms
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4 people found this helpful
The best of the best! Researchers have shown that magnesium helps reduce blood clotting in type 2 diabetes patients, lowering thrombosis risk. Magnesium is the second most prevalent intracellular electrolyte after potassium and is crucial for numerous enzymatic reactions related to glucose metabolism and vascular functions. Recent studies suggest inadequate magnesium intake correlates with higher incidences of type 2 diabetes and cardiovascular ailments. My 74-year-old mother, who has type 2 diabetes, has been taking this chelated magnesium regularly. A diet rich in magnesium, such as that from Dr. Best, even eases Alzheimer's symptomatology. Some scientists even propose that a magnesium deficit in the brain may trigger Parkinson's disease. I sincerely hope this insight proves helpful!

Nattokinase

7
Nattokinase shows potential in Alzheimer's
We investigated how nattokinase could help in treating Alzheimer's disease in rats. Over 10 weeks, we divided rats into groups, some receiving nattokinase along with treatments that mimic Alzheimer's symptoms.

The results showed that nattokinase improved memory and decreased harmful proteins in the brain. Additionally, brain scans revealed less damage after treatment. This suggests that nattokinase may hold promise as a therapeutic option for Alzheimer's, though more human research is needed to confirm its effectiveness.
9
Alzheimer's assistance
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This top cardiovascular supplement aids in blood flow and supports Alzheimer’s management effectively, avoiding the adverse effects of traditional medications like aspirin.

L Carnosine

8
l-Carnosine shows promise for Alzheimer's
We focused on understanding the impact of l-carnosine (CAR) in an innovative zebrafish model that mimics Alzheimer’s disease (AD). This model replicates key characteristics of the disease, including cognitive decline and abnormal tau protein behavior. By observing the effect of CAR on these symptoms, we aimed to explore its potential as a therapeutic agent.

Our results highlighted that l-carnosine can significantly improve learning abilities and reduce anxiety-like behaviors in these zebrafish. Notably, we discovered that CAR helps protect against dopamine release impairments, which are often associated with AD. Furthermore, the treatment indicated varying outcomes based on the sex of the zebrafish, suggesting that responses to CAR might differ across genders.

In essence, our findings provide strong evidence for l-carnosine as a promising candidate for future research into preventive therapies for Alzheimer’s disease. We are excited about the potential implications for delaying or mitigating the onset of this challenging condition.
9
Neuroprotective effects
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36 people found this helpful
This is a remarkable aid for brain dysfunction and optimising neurons. My nephew with autism has shown improvement alongside lipoic acid and DHA. My wife and I take it as well to help prevent Alzheimer's disease.

Dha

9
DHA's role in Alzheimer's management
We aimed to uncover how docosahexaenoic acid (DHA) might affect Alzheimer's disease, particularly in relation to nonalcoholic fatty liver disease (NAFLD). Our study involved 40 three-month-old male APP/PS1 mice, which are commonly used in Alzheimer's research, divided into four groups. These groups ate different diets—one with DHA, one with medium-chain triglycerides (MCTs), one with both, and one control—as we observed their impacts on liver health and amyloid-β (Aβ) accumulations over eight months.

Our findings showed that mice with Alzheimer's displayed both NAFLD and increased levels of Aβ in their brains. Interestingly, the combination of DHA and MCTs led to lower blood and liver lipids. It also alleviated fat buildup in the liver and reduced Aβ levels in both the brain and serum. Moreover, it effectively raised the levels of proteins linked to Aβ clearance while altering the expression of key enzymes related to liver lipid metabolism.

In essence, our research suggests that DHA, particularly when paired with MCTs, may offer protective benefits against the progression of NAFLD and simultaneously reduce Aβ accumulation. This could indicate a more significant response to metabolic changes in APP/PS1 mice compared to normal mice. Our study adds to the understanding of DHA's potential role in managing Alzheimer's disease through its effects on liver metabolism and Aβ processing.
9
Supports brain health
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1 people found this helpful
Excellent! DHA is vital for brain health, particularly for those with a family history of Alzheimer's. I appreciate this NOW product as it contains 500mg of DHA per capsule.

Vitamins

We sought to understand the potential role of α-tocopherol, a form of vitamin E, in preventing and treating Alzheimer's disease. Various research studies have indicated that this antioxidant might slow down the disease's progression or even reduce the risk of developing dementia. Our review delved into the biochemical mechanisms of α-tocopherol, highlighting its anti-inflammatory properties and ability to combat oxidative stress, which are vital in Alzheimer's pathology.

Interestingly, higher intake of α-tocopherol is linked to a lower incidence of mild cognitive impairment, suggesting its protective effects. However, we also noted that many people do not consume sufficient amounts of this vital nutrient. While there's a promising outlook for α-tocopherol supplementation as part of Alzheimer's management, we acknowledge that further research is necessary to draw definitive conclusions regarding its effectiveness and the mechanism behind its action.

Overall, our exploration into the relationship between vitamin E and Alzheimer's sheds light on a possible avenue for intervention, though clarity in treatment specifics and comprehensive studies are still required.
9
Alzheimer's treatment support
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Vitamin E is an essential antioxidant vitamin that safeguards cranial nerves and possibly averts cataracts. It is fat-soluble and well-absorbed. I've found that it has a proven track record in aiding Alzheimer’s treatment, and I take it three times daily for its benefits.

Omega 3 Fish Oil

4
Eicosapentaenoic acid affects brain levels
We explored the effects of eicosapentaenoic acid (EPA) on Alzheimer’s disease-related conditions through a study involving the administration of lysophosphatidylcholine-bound omega-3 fatty acids to mice with different genetic backgrounds. Specifically, we looked at how these supplements affected levels of EPA and docosahexaenoic acid (DHA) in the brains of mice that carry the apolipoprotein E ε3 (APOE3) or ε4 (APOE4) allele.

Over two and four months, the mice were given oral doses of LPC n-3, containing both EPA and DHA, and compared to a control group that received sunflower oil. After two months, we observed that the EPA levels increased in the brains of APOE3 mice, while there was no significant change in EPA or DHA levels for the APOE4 mice. After four months, both groups had elevated EPA levels, but DHA showed no significant improvement.

These findings suggest that while EPA supplementation can increase EPA levels in the brain, especially in those with the APOE3 allele, the same cannot be said for DHA or for APOE4 carriers. This highlights important differences in how genetic factors can influence the effectiveness of omega-3 fatty acid treatments.
9
Alzheimer prevention
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1 people found this helpful
The quality is superb. Omega-3 PUFAs provide energy for signalling between neurons, enhancing memory and attention. A deficiency impairs these functions. Studies show Omega-3 reduces the risk of Alzheimer’s and slows cognitive decline, especially in patients who start supplementation early.

Phosphatidylserine

7
Unsaturated lipids may combat Alzheimer’s
We explored how unsaturated phosphatidylserine and other lipids influence amyloid β (Aβ) aggregation in Alzheimer's disease. Using advanced techniques, we discovered that these lipids significantly impeded the formation of harmful Aβ plaques and reduced their toxicity to cells.

This suggests that incorporating unsaturated phospholipids into our diets might help slow down the advancement of Alzheimer’s. The study opens up exciting possibilities for using these lipids in developing new therapies aimed at fighting this debilitating disease.
9
Expert recommended
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Experts recommend Phosphatidylserine for its potential to prevent Alzheimer’s. I have been taking it for nearly three months now.

Sports Fish Oil Omegas

4
Eicosapentaenoic acid affects brain levels
We explored the effects of eicosapentaenoic acid (EPA) on Alzheimer’s disease-related conditions through a study involving the administration of lysophosphatidylcholine-bound omega-3 fatty acids to mice with different genetic backgrounds. Specifically, we looked at how these supplements affected levels of EPA and docosahexaenoic acid (DHA) in the brains of mice that carry the apolipoprotein E ε3 (APOE3) or ε4 (APOE4) allele.

Over two and four months, the mice were given oral doses of LPC n-3, containing both EPA and DHA, and compared to a control group that received sunflower oil. After two months, we observed that the EPA levels increased in the brains of APOE3 mice, while there was no significant change in EPA or DHA levels for the APOE4 mice. After four months, both groups had elevated EPA levels, but DHA showed no significant improvement.

These findings suggest that while EPA supplementation can increase EPA levels in the brain, especially in those with the APOE3 allele, the same cannot be said for DHA or for APOE4 carriers. This highlights important differences in how genetic factors can influence the effectiveness of omega-3 fatty acid treatments.
9
Comprehensive health benefits
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This Omega-3 fish oil soft gel is derived from high-quality deep-sea fish, ensuring purity and efficacy. It provides significant health benefits: it lowers cholesterol and triglyceride levels, promotes brain development, improves mood, and helps prevent Alzheimer’s. It effectively relieves joint inflammation and pain, making it a convenient and beneficial supplement with excellent quality and easy-to-take soft gel design.

Folic Acid

8
Folate may protect against Alzheimer’s
We examined the relationship between folate and Alzheimer's disease (AD) through a comprehensive analysis combining data from various studies. Our findings indicate that folate may provide protective effects against Alzheimer's, which is promising for those concerned about this challenging condition.

Specifically, we noted that individuals with higher folate levels could experience a decreased risk of developing Alzheimer's. This suggests that ensuring adequate folate intake could be beneficial for brain health.

However, it’s essential to understand that the impact of folate isn't a cure-all. While the association with Alzheimer's is favorable, more research is needed to clarify how folate levels might influence the progression or onset of this complex disorder.

Overall, our analysis underscores the potential of folate as part of a broader strategy for supporting cognitive health as we age.
9
Effective for Alzheimer’s
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This is folic acid at its finest! It can help with Alzheimer’s! I have been taking it for a long time and will continue to do so!

B12

8
Folate may protect against Alzheimer’s
We examined the relationship between folate and Alzheimer's disease (AD) through a comprehensive analysis combining data from various studies. Our findings indicate that folate may provide protective effects against Alzheimer's, which is promising for those concerned about this challenging condition.

Specifically, we noted that individuals with higher folate levels could experience a decreased risk of developing Alzheimer's. This suggests that ensuring adequate folate intake could be beneficial for brain health.

However, it’s essential to understand that the impact of folate isn't a cure-all. While the association with Alzheimer's is favorable, more research is needed to clarify how folate levels might influence the progression or onset of this complex disorder.

Overall, our analysis underscores the potential of folate as part of a broader strategy for supporting cognitive health as we age.
9
Enhanced nerve function
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11 people found this helpful
Unlike cyanocobalamin, methylcobalamin is a naturally occurring form of vitamin B12, better absorbed in our tissues. It aids in neuronal lipid production and promotes nerve regeneration, offering neuroprotective benefits essential for conditions like Alzheimer’s and Parkinson’s disease. A dosage of 1500mcg is safe and effective, as your body absorbs what it needs and excretes excess. It's crucial not to swallow the capsule but to let it dissolve in your mouth. The cost is reasonable too.

Resveratrol

9
Memory protection
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21 people found this helpful
Resveratrol positively affects the nervous system and protects brain cells, potentially preventing memory issues and Alzheimer's disease. It also improves blood circulation in the brain, alleviating dizziness and weakness. If this review helps you, please like it!
9
Neuroprotection
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9 people found this helpful
Resveratrol is a potent antioxidant fighting free radicals and has anti-inflammatory properties. It may help slow the progression of Alzheimer's disease and increase cerebral blood flow. Generally safe, it does require caution when taken with certain medications.

Alpha Lipoic Acid

9
Alleviates Alzheimer's pain
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Alpha-lipoic acid is an antioxidant with proven benefits that alleviate various diseases such as diabetes, Alzheimer's, oncology, cardiovascular issues, and obesity. The capsules are economical for a six-month supply. After a week of use, I want to eat less often, my mind is clearer, and pancreatic pain has diminished. The capsules are pleasant-smelling, pale yellow, and easy to swallow. The quality is excellent; I recommend it!
7.5
Enhances life quality
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One of the best antioxidant vitamins (oxidants) and alpha-lipoic acid is renowned for increasing the sensitivity of insulin secretion, relieving nerve pain, delaying skin ageing, and slowing the progression of Alzheimer's.

Ginkgo Biloba

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Family use
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17 people found this helpful
My family regularly uses ginkgo biloba extract due to its impressive benefits. It helps slow down the ageing process and has a positive impact on conditions like Alzheimer’s, improving memory and clarity of thought. I highly recommend it for anyone looking to support their health.
9
Effective for elderly
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11 people found this helpful
I've been buying this ginkgo supplement for my aunt, who began to forget things. After taking it, we noticed a remarkable difference—she no longer forgets or repeats herself, which is crucial for those showing signs of Alzheimer’s. A daily pill has made significant improvements.

Selenium

9
Repairs damaged nerves
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My physician mentioned that selenium can repair damaged nerves and prevent Alzheimer's. This trace element is incredibly beneficial for overall health.
9
Essential for immunity
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Selenium is essential for both men and women's health, with a significant portion of the population being deficient. It boosts immunity, acts as an antioxidant, protects cells from ageing, aids Alzheimer’s prevention, helps asthmatics, and combats inflammation. Since the body cannot produce selenium, obtaining it through food is crucial. I highly recommend this reliable product.

Coconut Supplements

9
Alzheimer’s relief
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1 people found this helpful
Excellent! It is ideal for the elderly, particularly in easing Alzheimer’s symptoms. I plan to reorder as the packaging matches the price well.
9
Clear difference
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I purchased this for my grandmother, who has Alzheimer’s, as recommended by her doctor. I noticed a clear difference when she stopped taking it; it genuinely helps, even if just a little.

Fiber

7.5
Enhances memory clarity
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42 people found this helpful
Alpha GPC greatly enhances my nootropic regimen, particularly in improving short-term memory. I incorporate it with a group of B vitamins, DMAE capsules, and magnesium. Memory issues, even in young individuals, can sometimes stem from forgetfulness due to stress. I encourage anyone facing these challenges, including those concerned about Alzheimer’s, to consider it as it has greatly benefitted me.
7.5
Supports cognitive function
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39 people found this helpful
Natural Vitamin C is a key antioxidant, vital for collagen production and immune support, with a neuroprotective effect known to aid against cognitive decline and Alzheimer’s disease. I’ve been taking it for over twenty years, finding it essential for health. On the Iherb website, there are varieties of vitamin C, with the natural forms being acerola and camu-camu, which are found in fruits and vegetables. My chosen product, Vitamin C Alive! from Nature’s Way, contains bioflavonoids that enhance absorption and is beautifully packaged. I highly recommend it!

Acetyl L Carnitine

7.5
Visible improvement noted
Most Useful Review
1 people found this helpful
Excellent! I purchased it for my 85-year-old father, who is in the early stages of Alzheimer's. After three doses, he began to speak and smile again, which was a pleasant surprise, even if the improvement was modest. We're currently using one capsule in the morning, with plans to increase it to two.
7.5
Memory impairment treatment
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1 people found this helpful
The quality is exceptional, with clean ingredients in appropriate quantities. Carnitine is known to effectively aid memory impairment and treat Alzheimer’s, as discussed by Dr. Karim.