NOW Foods, Milk Thistle Extract, Double Strength, 300 mg, 200 Veg Capsules | | |
Silibinin counters Alzheimer’s memory lossSilibinin prevents amyloid beta peptide-induced memory impairment and oxidative stress in mice. We examined the effects of silibinin, a component of the milk thistle plant, on memory impairment linked to amyloid beta-induced oxidative stress in mice. After administering silibinin alongside amyloid beta, we observed promising results; silibinin appeared to prevent memory loss and reduced oxidative damage in the mice's brains.
Our findings suggest that silibinin could be a beneficial treatment for protecting against cognitive decline in Alzheimer's disease. This could open new pathways in the search for effective therapies. Neuroprotective properties Most Useful Review 92 people found this helpful Since ancient times, milk thistle has been used for neurological diseases. Today, it treats conditions like Parkinson's and Alzheimer’s. Its anti-inflammatory and antioxidant properties may provide neuroprotective effects. |
Jarrow Formulas, Curcumin 95, Turmeric Extract, 500 mg, 120 Veggie Capsules | | |
Curcumin derivative shows Alzheimer's promiseNew low-dose curcumin derivative with therapeutic potential in Alzheimer's disease: Results from an in vitro and in vivo study in mice. We examined the potential of a curcumin derivative, known as Derivative 27, to treat Alzheimer's disease (AD). Curcumin, a compound found in turmeric, has previously been recognized for its ability to interfere with amyloid-β (Aβ) peptide aggregates, a hallmark of AD. The study focused on enhancing curcumin's effectiveness at lower doses, aiming to make treatment more accessible for patients.
Through rigorous testing, both in vitro and in vivo, we evaluated the anti-inflammatory, antioxidant, and anti-amyloidogenic properties of Derivative 27. In laboratory settings, the compound showed impressive results by significantly reducing the production of nitric oxide and various pro-inflammatory proteins. Additionally, it activated a key protective transcription factor known as Nrf2, illustrating its potential to combat neuroinflammation.
In a more practical application, we tested Derivative 27 on one-year-old APP/PS1 mice, a model for Alzheimer's. After administering the treatment daily for 28 days, we observed improvements in the mice's short-term spatial memory. Significant reductions in hippocampal pro-inflammatory markers and Aβ levels were also noted, supporting the idea that this new curcumin derivative could be beneficial in the fight against Alzheimer’s.
Overall, this research opens the door to developing modified curcumin compounds that could lead to effective low-dose treatments for Alzheimer's disease, all while highlighting the therapeutic potential of turmeric derivatives in neurodegenerative conditions. Alzheimer prevention Most Useful Review A highly recommended product! This well-known brand provides quality ingredients, offering a capsule a day that potentially helps prevent Alzheimer's and cancer. |
NOW Foods, Choline & Inositol, 100 Veg Capsules | | |
D-Pinitol shows promise in Alzheimer'sTherapeutic Efficacy of the Inositol D-Pinitol as a Multi-Faceted Disease Modifier in the 5×FAD Humanized Mouse Model of Alzheimer's Amyloidosis. We explored the potential of D-Pinitol (DPIN), a compound derived from carob pods, as a game-changing treatment for Alzheimer's disease (AD). With AD being a leading cause of dementia and lacking effective long-term solutions, we sought to evaluate how DPIN could alter the course of this debilitating condition.
Our research focused on the 5×FAD mouse model, which closely mimics the Alzheimer-like symptoms in humans. Through chronic oral administration of DPIN at a dosage of 200 mg/kg/day, we observed various promising effects. Notably, DPIN improved cognitive performance in the mice, reduced harmful amyloid beta and tau protein levels, and even enhanced the expression of insulin-degrading enzymes that could help regulate insulin in the system.
Additionally, DPIN seemed to support gut health, countering chronic inflammation and restoring the balance of gut microbiota. This is significant because gut issues are increasingly recognized as a contributing factor to Alzheimer's. The compound not only helped repair intestinal barriers but also reduced inflammation markers associated with a leaky gut.
Overall, these findings suggest that D-Pinitol could serve as a multifaceted approach to modify the progression of Alzheimer's in its early stages, potentially shifting the landscape of how we treat this serious condition. Combats memory loss Most Useful Review Choline is crucial for human growth, development, and various bodily functions. Highest in dairy and meat, it assists nerve cells in communication. Recent studies suggest choline may combat Alzheimer's disease and improve memory. It also maintains cell structure and liver health, vital for a healthy nervous system and brain development. |
Doctor's Best, High Absorption Magnesium, 200 mg, 120 Tablets, (100 mg per Tablet) | | |
Magnesium's impact on Alzheimer's treatmentMagnesium-L-threonate treats Alzheimer's disease by modulating the microbiota-gut-brain axis. We explored the potential benefits of magnesium-L-threonate for Alzheimer's disease, particularly how it interacts with the gut microbiome. In our study, we focused on a specific mouse model that simulates Alzheimer's by using double-transgenic groups expressing particular proteins associated with the disease. By administering magnesium-L-threonate, we aimed to see if it could improve cognitive functions and alter gut bacteria positively.
Our findings revealed that magnesium-L-threonate not only enhanced learning and memory but also significantly altered the balance of gut microbiota. We observed a reduction in the harmful bacteria Allobaculum, while beneficial strains like Bifidobacterium and Turicibacter increased.
Additionally, our research detected changes in serum metabolites linked to neurodegenerative diseases, strengthening the idea that magnesium could play a role in brain health by influencing gut health. Importantly, we also noted improvements in intestinal barrier function, indicating that magnesium-L-threonate might mitigate some effects of Alzheimer's by repairing gut-related issues.
Overall, we believe that magnesium-L-threonate holds promise as a therapeutic option in managing Alzheimer’s symptoms, emphasizing the intricate relationship between the gut and brain in this condition. Alleviates symptoms Most Useful Review 4 people found this helpful The best of the best! Researchers have shown that magnesium helps reduce blood clotting in type 2 diabetes patients, lowering thrombosis risk. Magnesium is the second most prevalent intracellular electrolyte after potassium and is crucial for numerous enzymatic reactions related to glucose metabolism and vascular functions. Recent studies suggest inadequate magnesium intake correlates with higher incidences of type 2 diabetes and cardiovascular ailments. My 74-year-old mother, who has type 2 diabetes, has been taking this chelated magnesium regularly. A diet rich in magnesium, such as that from Dr. Best, even eases Alzheimer's symptomatology. Some scientists even propose that a magnesium deficit in the brain may trigger Parkinson's disease. I sincerely hope this insight proves helpful! |
Doctor's Best, Nattokinase, 2,000 FUs, 270 Veggie Caps | | |
Nattokinase shows promise for Alzheimer’sNattokinase prevents β-amyloid peptide (Aβ) induced neuropsychiatric complications, neuroinflammation and BDNF signalling disruption in mice. We explored how chronic Nattokinase (NK) treatment influences neuropsychiatric complications tied to Alzheimer's disease in mice. By administering NK to mice injected with β-amyloid peptide, we observed reduced signs of depression, anxiety, and memory impairments—key indicators of Alzheimer’s progression. NK treatment led to improvements in cognitive performance and normalized chemical changes in the brain, similar to the effects of donepezil, a known Alzheimer’s medication. This suggests that Nattokinase could be a promising avenue for addressing behavioral and cognitive challenges in Alzheimer’s. Alzheimer's assistance Most Useful Review This top cardiovascular supplement aids in blood flow and supports Alzheimer’s management effectively, avoiding the adverse effects of traditional medications like aspirin. |
NOW Foods, L-Carnosine, 500 mg, 100 Veg Capsules | | |
Carnosine's potential against Alzheimer'sTwo human metabolites rescue a C. elegans model of Alzheimer's disease via a cytosolic unfolded protein response. We discovered interesting insights into how l-carnosine, an endogenous metabolite, impacts Alzheimer's disease. By analyzing data from the Human Metabolome Database, we identified l-carnosine, alongside kynurenic acid, as substances that can inhibit the aggregation of amyloid beta peptide (Aβ), which is commonly associated with Alzheimer’s.
Our findings highlighted that l-carnosine works by triggering a cytosolic unfolded protein response. This involves a transcription factor called HSF-1 and different chaperones, specifically HSP40/J-proteins DNJ-12 and DNJ-19. This mechanism indicates that l-carnosine not only plays a role in reducing protein aggregation but may also suggest potential anti-aging benefits.
The link we established between metabolite homeostasis and protein homeostasis presents promising avenues for preventative measures against neurodegenerative disorders. It's exciting to think about how exploring the roles of metabolites like l-carnosine could offer new strategies in combating diseases that impact so many lives. Neuroprotective effects Most Useful Review 36 people found this helpful This is a remarkable aid for brain dysfunction and optimising neurons. My nephew with autism has shown improvement alongside lipoic acid and DHA. My wife and I take it as well to help prevent Alzheimer's disease. |
NOW Foods, Double Strength DHA-500 Fish Oil, 180 Softgels | | |
DHA shows promise in Alzheimer'sNose-to-brain delivery of DHA-loaded nanoemulsions: A promising approach against Alzheimer's disease. We investigated the potential benefits of docosahexaenoic acid (DHA) in fighting Alzheimer's disease (AD) through a novel intranasal administration method. By using a specially formulated nanoemulsion that protects DHA from oxidation, we aimed to enhance its delivery to the brain. In our study, we administered this DHA-rich nanoemulsion to J20 mice, a well-known transgenic model for AD.
The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.
Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients. Supports brain health Most Useful Review 1 people found this helpful Excellent! DHA is vital for brain health, particularly for those with a family history of Alzheimer's. I appreciate this NOW product as it contains 500mg of DHA per capsule. |
NOW Foods, E-400 with Mixed Tocopherols, 268 mg (400 IU), 100 Softgels | | |
Vitamin E's potential in Alzheimer'sThe role of α-tocopherol in the prevention and treatment of Alzheimer's disease. We sought to understand the potential role of α-tocopherol, a form of vitamin E, in preventing and treating Alzheimer's disease. Various research studies have indicated that this antioxidant might slow down the disease's progression or even reduce the risk of developing dementia. Our review delved into the biochemical mechanisms of α-tocopherol, highlighting its anti-inflammatory properties and ability to combat oxidative stress, which are vital in Alzheimer's pathology.
Interestingly, higher intake of α-tocopherol is linked to a lower incidence of mild cognitive impairment, suggesting its protective effects. However, we also noted that many people do not consume sufficient amounts of this vital nutrient. While there's a promising outlook for α-tocopherol supplementation as part of Alzheimer's management, we acknowledge that further research is necessary to draw definitive conclusions regarding its effectiveness and the mechanism behind its action.
Overall, our exploration into the relationship between vitamin E and Alzheimer's sheds light on a possible avenue for intervention, though clarity in treatment specifics and comprehensive studies are still required. Alzheimer's treatment support Most Useful Review Vitamin E is an essential antioxidant vitamin that safeguards cranial nerves and possibly averts cataracts. It is fat-soluble and well-absorbed. I've found that it has a proven track record in aiding Alzheimer’s treatment, and I take it three times daily for its benefits. |
Garden of Life, Dr. Formulated Brain Health, 100% Organic Coconut MCT Oil, Unflavored, 13 g, 32 fl oz (946 ml) | | |
Effective for Alzheimer's Most Useful Review Really works brilliantly. All Alzheimer’s and dementia patients should consume it daily. Good for memory Most Useful Review I purchased another box for my dear father. It aids memory and offers protection against Alzheimer’s, God willing. |
NOW Foods, Super Omega 3-6-9, 1,200 mg, 90 Softgels | | |
Improved mental health Most Useful Review With regular use, my energy increases and the health of my eyes improves. Omega-3 helps prevent Alzheimer’s disease and osteoporosis, while also strengthening my hair and nails. I was prescribed these by my doctor, and now I take them regularly. Prevention of Alzheimer's Most Useful Review Omega 3-6-9 is invaluable for my heart and immunity. It acts as a preventative measure against age-related changes, decreasing the risk of Alzheimer’s and other ailments. |
NOW Foods, Omega-3 Fish Oil, 1,000 mg, 180 EPA - 120 DHA, 200 Softgels | | |
DHA shows promise in Alzheimer'sNose-to-brain delivery of DHA-loaded nanoemulsions: A promising approach against Alzheimer's disease. We investigated the potential benefits of docosahexaenoic acid (DHA) in fighting Alzheimer's disease (AD) through a novel intranasal administration method. By using a specially formulated nanoemulsion that protects DHA from oxidation, we aimed to enhance its delivery to the brain. In our study, we administered this DHA-rich nanoemulsion to J20 mice, a well-known transgenic model for AD.
The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.
Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients. Alzheimer prevention Most Useful Review 1 people found this helpful The quality is superb. Omega-3 PUFAs provide energy for signalling between neurons, enhancing memory and attention. A deficiency impairs these functions. Studies show Omega-3 reduces the risk of Alzheimer’s and slows cognitive decline, especially in patients who start supplementation early. |
Natrol, Omega-3 Fish Oil, Lemon, 1,000 mg, 150 Softgels | | |
DHA shows promise in Alzheimer'sNose-to-brain delivery of DHA-loaded nanoemulsions: A promising approach against Alzheimer's disease. We investigated the potential benefits of docosahexaenoic acid (DHA) in fighting Alzheimer's disease (AD) through a novel intranasal administration method. By using a specially formulated nanoemulsion that protects DHA from oxidation, we aimed to enhance its delivery to the brain. In our study, we administered this DHA-rich nanoemulsion to J20 mice, a well-known transgenic model for AD.
The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.
Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients. Memory support Most Useful Review Omega-3 is crucial for preventing Alzheimer's and supporting heart health. I take 2 capsules daily and have also tried a higher dosage. This product is effective, with no fishy aftertaste and a pleasant lemon flavour. |
Carlson, Wild Norwegian, Elite Omega-3 Gems®, Natural Lemon, 120 Soft Gels | | |
DHA shows promise in Alzheimer'sNose-to-brain delivery of DHA-loaded nanoemulsions: A promising approach against Alzheimer's disease. We investigated the potential benefits of docosahexaenoic acid (DHA) in fighting Alzheimer's disease (AD) through a novel intranasal administration method. By using a specially formulated nanoemulsion that protects DHA from oxidation, we aimed to enhance its delivery to the brain. In our study, we administered this DHA-rich nanoemulsion to J20 mice, a well-known transgenic model for AD.
The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.
Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients. Vitality enhancement Most Useful Review Great omega for the heart! Omega-3 is a beneficial supplement for all ages but especially for children and the elderly. It improves brain function and reduces the risk of Alzheimer's disease. I have taken it for a long time and find it both necessary and effective; the improvements are apparent at both physical and emotional levels. One package suffices for a full course. Omega-3 supports the cardiovascular system, and these capsules are easy to swallow. After taking it, I feel invigorated. My biochemical blood tests have significantly improved. |
Solgar, Omega 3, EPA & DHA, Triple Strength, 950 mg, 100 Softgels | | |
Memory control improved Most Useful Review 1 people found this helpful Best! It is very convenient to take one capsule a day, with an excellent dosage. I observed results after using it. In a man with Alzheimer's disease, some bodily functions were restored, allowing him to regain control over aspects he could not manage before. Enhanced memory noted Most Useful Review I have been taking Omega-3 triple concentration of 950mg from Solgar for nearly a month, as recommended by my doctor. My health has improved noticeably, with enhanced memory and fewer headaches. It's beneficial for the elderly to support brain function and prevent Alzheimer's disease, among other conditions. I highly recommend monitoring health for better longevity! |
Jarrow Formulas, PS100, Phosphatidylserine, 100 mg, 120 Softgels | | |
Phosphatidylserine beneficial for memoryEffect of phosphatidylserine on memory in patients and rats with Alzheimer's disease. We explored how phosphatidylserine (PS) affects memory in patients and rats with Alzheimer's disease. The study involved 57 patients split into control and treatment groups, while AD rats were given various doses of PS for 12 weeks.
Results showed that patients and treated rats improved memory scores and brain health significantly. The higher dose of PS was particularly effective in enhancing memory and reducing harmful brain inflammation.
Overall, phosphatidylserine appears promising as a treatment to boost memory function in Alzheimer's patients. Expert recommended Most Useful Review Experts recommend Phosphatidylserine for its potential to prevent Alzheimer’s. I have been taking it for nearly three months now. |
Sports Research, Omega-3 Fish Oil, Triple Strength , 30 Softgels | | |
DHA shows promise in Alzheimer'sNose-to-brain delivery of DHA-loaded nanoemulsions: A promising approach against Alzheimer's disease. We investigated the potential benefits of docosahexaenoic acid (DHA) in fighting Alzheimer's disease (AD) through a novel intranasal administration method. By using a specially formulated nanoemulsion that protects DHA from oxidation, we aimed to enhance its delivery to the brain. In our study, we administered this DHA-rich nanoemulsion to J20 mice, a well-known transgenic model for AD.
The results were promising. After treatment, the mice showed notable improvements in their well-being and memory performance, which we measured through their ability to navigate spatial tasks. Additionally, we observed a significant reduction in harmful amyloid deposits, oxidative stress, and neuroinflammation within their brain tissues. This positive outcome could potentially stem from DHA's ability to affect specific processes in the brain, such as the inactivation of GSK3β, a kinase associated with AD.
Overall, our findings suggest that intranasal DHA treatment not only has therapeutic effects but may also modify the progression of Alzheimer's disease. Considering that DHA has already demonstrated safety in humans, we believe there is a strong case for conducting clinical trials to explore this approach further for Alzheimer's patients. Comprehensive health benefits Most Useful Review This Omega-3 fish oil soft gel is derived from high-quality deep-sea fish, ensuring purity and efficacy. It provides significant health benefits: it lowers cholesterol and triglyceride levels, promotes brain development, improves mood, and helps prevent Alzheimer’s. It effectively relieves joint inflammation and pain, making it a convenient and beneficial supplement with excellent quality and easy-to-take soft gel design. |
NOW Foods, Folic Acid, 800 mcg, 250 Tablets | | |
Folate may protect against Alzheimer’sCausal relationship between B vitamins and neuropsychiatric disorders: A systematic review and meta-analysis. We examined the relationship between folate and Alzheimer's disease (AD) through a comprehensive analysis combining data from various studies. Our findings indicate that folate may provide protective effects against Alzheimer's, which is promising for those concerned about this challenging condition.
Specifically, we noted that individuals with higher folate levels could experience a decreased risk of developing Alzheimer's. This suggests that ensuring adequate folate intake could be beneficial for brain health.
However, it’s essential to understand that the impact of folate isn't a cure-all. While the association with Alzheimer's is favorable, more research is needed to clarify how folate levels might influence the progression or onset of this complex disorder.
Overall, our analysis underscores the potential of folate as part of a broader strategy for supporting cognitive health as we age. Menopause relief Most Useful Review After forty, women require folic acid to alleviate menopause symptoms. A sufficient intake will help preserve memory long-term and reduce the risk of Alzheimer's disease. |
Jarrow Formulas, Vegan Methyl Folate, Extra Strength, 400 mcg, 60 Veggie Capsules | | |
Folate may protect against Alzheimer’sCausal relationship between B vitamins and neuropsychiatric disorders: A systematic review and meta-analysis. We examined the relationship between folate and Alzheimer's disease (AD) through a comprehensive analysis combining data from various studies. Our findings indicate that folate may provide protective effects against Alzheimer's, which is promising for those concerned about this challenging condition.
Specifically, we noted that individuals with higher folate levels could experience a decreased risk of developing Alzheimer's. This suggests that ensuring adequate folate intake could be beneficial for brain health.
However, it’s essential to understand that the impact of folate isn't a cure-all. While the association with Alzheimer's is favorable, more research is needed to clarify how folate levels might influence the progression or onset of this complex disorder.
Overall, our analysis underscores the potential of folate as part of a broader strategy for supporting cognitive health as we age. Effective for Alzheimer’s Most Useful Review This is folic acid at its finest! It can help with Alzheimer’s! I have been taking it for a long time and will continue to do so! |
NOW Foods, B-12, 1,000 mcg, 100 Lozenges | | |
Folate may protect against Alzheimer’sCausal relationship between B vitamins and neuropsychiatric disorders: A systematic review and meta-analysis. We examined the relationship between folate and Alzheimer's disease (AD) through a comprehensive analysis combining data from various studies. Our findings indicate that folate may provide protective effects against Alzheimer's, which is promising for those concerned about this challenging condition.
Specifically, we noted that individuals with higher folate levels could experience a decreased risk of developing Alzheimer's. This suggests that ensuring adequate folate intake could be beneficial for brain health.
However, it’s essential to understand that the impact of folate isn't a cure-all. While the association with Alzheimer's is favorable, more research is needed to clarify how folate levels might influence the progression or onset of this complex disorder.
Overall, our analysis underscores the potential of folate as part of a broader strategy for supporting cognitive health as we age. |
NOW Foods, Methyl B-12, 1,000 mcg, 100 Lozenges | | |
Vitamin B12's limited effect on Alzheimer'sRole of vitamin B12 and folic acid in treatment of Alzheimer's disease: a meta-analysis of randomized control trials. We explored the potential role of vitamin B12, alongside folic acid, in slowing the progression of Alzheimer's disease (AD) through a meta-analysis of randomized control trials. Our aim was to determine whether these supplements might improve cognitive function, daily life activities, and influence blood homocysteine levels in individuals diagnosed with AD.
After carefully sifting through studies, we found five that met our criteria. These studies assessed the cognitive changes in participants through the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog). Additionally, they examined the impact on daily functioning as well as blood homocysteine levels.
The results showed that after six months of treatment, participants taking vitamin B12 and folic acid did experience a slight improvement in MMSE scores compared to those on a placebo. However, there was no significant change in the ADAS-Cog scores, which means some cognitive aspects didn’t show marked improvement. Likewise, daily life functioning did not see any benefits from the supplements.
Importantly, we also noted a significant reduction in blood homocysteine levels following the supplementation, suggesting a biochemical effect of the treatment. Overall, while vitamin B12 shows promise in enhancing some cognitive measures, it does not translate directly into broader cognitive or daily functioning improvements in Alzheimer's patients. Supports neuron function Most Useful Review 9 people found this helpful Unlike cyanocobalamin, methylcobalamin is a naturally occurring form of vitamin B12, more active and better absorbed in higher amounts. It aids neuronal lipid production, promotes axonal nerve regeneration, and has neuroprotective properties that enable neurons to function properly, thus assisting with Alzheimer’s disease, Parkinson’s disease, dementia, and neuropathic syndromes. A starting dose of 1000mcg is advisable, and it is considered non-toxic, as the body absorbs only what it needs—any excess is excreted. The tablets are small, pink, and sweet, and should be melted in the mouth rather than swallowed. |
Jarrow Formulas, Vegan Methyl B-12, Maximum Strength, Cherry, 5,000 mcg, 60 Chewable Tablets | | |
Vitamin B12's limited effect on Alzheimer'sRole of vitamin B12 and folic acid in treatment of Alzheimer's disease: a meta-analysis of randomized control trials. We explored the potential role of vitamin B12, alongside folic acid, in slowing the progression of Alzheimer's disease (AD) through a meta-analysis of randomized control trials. Our aim was to determine whether these supplements might improve cognitive function, daily life activities, and influence blood homocysteine levels in individuals diagnosed with AD.
After carefully sifting through studies, we found five that met our criteria. These studies assessed the cognitive changes in participants through the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog). Additionally, they examined the impact on daily functioning as well as blood homocysteine levels.
The results showed that after six months of treatment, participants taking vitamin B12 and folic acid did experience a slight improvement in MMSE scores compared to those on a placebo. However, there was no significant change in the ADAS-Cog scores, which means some cognitive aspects didn’t show marked improvement. Likewise, daily life functioning did not see any benefits from the supplements.
Importantly, we also noted a significant reduction in blood homocysteine levels following the supplementation, suggesting a biochemical effect of the treatment. Overall, while vitamin B12 shows promise in enhancing some cognitive measures, it does not translate directly into broader cognitive or daily functioning improvements in Alzheimer's patients. Quality recommendation Most Useful Review This is a very high-quality product. I recommend it for my patients who exhibit mild Alzheimer’s and neurological issues. |
Solgar, Methylcobalamin (Vitamin B12), 1,000 mcg, 60 Nuggets | | |
Vitamin B12's limited effect on Alzheimer'sRole of vitamin B12 and folic acid in treatment of Alzheimer's disease: a meta-analysis of randomized control trials. We explored the potential role of vitamin B12, alongside folic acid, in slowing the progression of Alzheimer's disease (AD) through a meta-analysis of randomized control trials. Our aim was to determine whether these supplements might improve cognitive function, daily life activities, and influence blood homocysteine levels in individuals diagnosed with AD.
After carefully sifting through studies, we found five that met our criteria. These studies assessed the cognitive changes in participants through the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog). Additionally, they examined the impact on daily functioning as well as blood homocysteine levels.
The results showed that after six months of treatment, participants taking vitamin B12 and folic acid did experience a slight improvement in MMSE scores compared to those on a placebo. However, there was no significant change in the ADAS-Cog scores, which means some cognitive aspects didn’t show marked improvement. Likewise, daily life functioning did not see any benefits from the supplements.
Importantly, we also noted a significant reduction in blood homocysteine levels following the supplementation, suggesting a biochemical effect of the treatment. Overall, while vitamin B12 shows promise in enhancing some cognitive measures, it does not translate directly into broader cognitive or daily functioning improvements in Alzheimer's patients. Supports neurological function Most Useful Review 6 people found this helpful A tablet under the tongue after breakfast provides essential Vitamin B12, which is crucial for hormonal and metabolic functions. This vitamin is necessary for energy production, normal neurological function, and blood formation. It aids in the transport of nutrients and protects vascular walls, preventing cardiovascular issues, Alzheimer's, and dementia. The B12 synergy is vital for over 100 functions daily. |
Doctor's Best, Fully Active B12, 1,500 mcg, 180 Veggie Caps | | |
Vitamin B12's limited effect on Alzheimer'sRole of vitamin B12 and folic acid in treatment of Alzheimer's disease: a meta-analysis of randomized control trials. We explored the potential role of vitamin B12, alongside folic acid, in slowing the progression of Alzheimer's disease (AD) through a meta-analysis of randomized control trials. Our aim was to determine whether these supplements might improve cognitive function, daily life activities, and influence blood homocysteine levels in individuals diagnosed with AD.
After carefully sifting through studies, we found five that met our criteria. These studies assessed the cognitive changes in participants through the Mini-Mental State Examination (MMSE) and the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog). Additionally, they examined the impact on daily functioning as well as blood homocysteine levels.
The results showed that after six months of treatment, participants taking vitamin B12 and folic acid did experience a slight improvement in MMSE scores compared to those on a placebo. However, there was no significant change in the ADAS-Cog scores, which means some cognitive aspects didn’t show marked improvement. Likewise, daily life functioning did not see any benefits from the supplements.
Importantly, we also noted a significant reduction in blood homocysteine levels following the supplementation, suggesting a biochemical effect of the treatment. Overall, while vitamin B12 shows promise in enhancing some cognitive measures, it does not translate directly into broader cognitive or daily functioning improvements in Alzheimer's patients. Enhanced nerve function Most Useful Review 11 people found this helpful Unlike cyanocobalamin, methylcobalamin is a naturally occurring form of vitamin B12, better absorbed in our tissues. It aids in neuronal lipid production and promotes nerve regeneration, offering neuroprotective benefits essential for conditions like Alzheimer’s and Parkinson’s disease. A dosage of 1500mcg is safe and effective, as your body absorbs what it needs and excretes excess. It's crucial not to swallow the capsule but to let it dissolve in your mouth. The cost is reasonable too. |
NOW Foods, Sunflower Lecithin, 1,200 mg, 200 Softgels | | |
Brain rejuvenation Most Useful Review It rejuvenates the brain and combats Alzheimer's. Enhanced memory Most Useful Review 1 people found this helpful I bought lecithin primarily for my son, who's 6, and we've all experienced its benefits. It has positively influenced memory, speech and attention - my child is now more active and curious. Lecithin serves as a natural antioxidant, protecting the liver while supporting the reproductive system. My mum takes it to prevent Alzheimer’s. It’s a tasty addition to cottage cheese, yogurt, or juices. I definitely recommend it! ❤️ |
Nature's Way, Organic MCT Oil, 16 fl oz (480 ml) | | |
Normalizes behaviour Most Useful Review 3 people found this helpful It appears my mum has more 'normal' moments after taking this for 6 months, which seems beneficial for Alzheimer's patients. Supports memory function Most Useful Review 2 people found this helpful Ingredients: Organic MCT oil, beneficial for candida and memory, with anti-Alzheimer's properties. It is highly effective and comes in a substantial quantity, making it one of the best products available. I strongly recommend it. |
NOW Foods, Virgin Coconut Oil, 1,000 mg, 120 Softgels | | |
Lifesaver recommendation Most Useful Review 5 people found this helpful GREAT product! Despite mixed reviews, I've taken these pills for months without aftertaste or odour issues. While they are slightly large, they are easy to swallow. I will be taking these for life due to research on coconut oil's benefits for Alzheimer's. Recommended by my doctor, I highly advise anyone with family affected by Alzheimer’s to give them a try! Highly beneficial Most Useful Review 1 people found this helpful Excellent! Beneficial for Alzheimer's patients. |
Doctor's Best, NAC Detox Regulators with Seleno Excell®, 60 Veggie Caps | | |
Good value for money Most Useful Review 1 people found this helpful I purchased this to assist my mother in managing her Alzheimer's disease. NAC, a precursor to glutathione, promotes detoxification and protects against oxidative stress. This supplement includes molybdenum and selenium, which enhance NAC's effectiveness, offering excellent value for money. Improves symptoms Most Useful Review NAC is a powerful antioxidant and semi-essential amino acid that bolsters immune function. It is commonly used to treat respiratory conditions, Tylenol overdose, and kidney damage. Moreover, NAC has been associated with enhanced mental health, increased fertility, and even potential improvement in Alzheimer's symptoms. |
NOW Foods, Resveratrol, 200 mg, 120 Veg Capsules | | |
Memory protection Most Useful Review 21 people found this helpful Resveratrol positively affects the nervous system and protects brain cells, potentially preventing memory issues and Alzheimer's disease. It also improves blood circulation in the brain, alleviating dizziness and weakness. If this review helps you, please like it! Neuroprotection Most Useful Review 9 people found this helpful Resveratrol is a potent antioxidant fighting free radicals and has anti-inflammatory properties. It may help slow the progression of Alzheimer's disease and increase cerebral blood flow. Generally safe, it does require caution when taken with certain medications. |
Doctor's Best, Alpha-Lipoic Acid 600, 600 mg, 180 Veggie Caps | | |
Alleviates Alzheimer's pain Most Useful Review Alpha-lipoic acid is an antioxidant with proven benefits that alleviate various diseases such as diabetes, Alzheimer's, oncology, cardiovascular issues, and obesity. The capsules are economical for a six-month supply. After a week of use, I want to eat less often, my mind is clearer, and pancreatic pain has diminished. The capsules are pleasant-smelling, pale yellow, and easy to swallow. The quality is excellent; I recommend it! Enhances life quality Most Useful Review One of the best antioxidant vitamins (oxidants) and alpha-lipoic acid is renowned for increasing the sensitivity of insulin secretion, relieving nerve pain, delaying skin ageing, and slowing the progression of Alzheimer's. |
NOW Foods, Ginkgo Biloba, Double Strength, 120 mg, 200 Veg Capsules | | |
Improves memory clarity Most Useful Review Ginkgo is beneficial for individuals experiencing mild dementia, Alzheimer's, anxiety, and memory difficulties. It has been effective for my father by rebooting his memory and improving clarity, which has encouraged me to continue purchasing it. The improvements in his condition validate its benefits, and I will keep buying this product for its evident efficacy. Improves cognitive function Most Useful Review 1 people found this helpful The extract from the Ginkgo biloba tree is rich in antioxidants, which assist in normalising metabolism and preventing tissue ageing. It effectively reduces inflammation in tissues and enhances nitric oxide circulation, improving heart and organ nutrition. Prolonged use of this extract has shown a reduction in anxiety and dementia symptoms associated with Alzheimer's disease, making it valuable for cognitive health. Its benefits in enhancing cerebral function highlight its importance in herbal medicine. |
Doctor's Best, Extra Strength Ginkgo, 120 mg, 360 Veggie Caps | | |
Family use Most Useful Review 17 people found this helpful My family regularly uses ginkgo biloba extract due to its impressive benefits. It helps slow down the ageing process and has a positive impact on conditions like Alzheimer’s, improving memory and clarity of thought. I highly recommend it for anyone looking to support their health. Effective for elderly Most Useful Review 11 people found this helpful I've been buying this ginkgo supplement for my aunt, who began to forget things. After taking it, we noticed a remarkable difference—she no longer forgets or repeats herself, which is crucial for those showing signs of Alzheimer’s. A daily pill has made significant improvements. |
NOW Foods, Selenium, 200 mcg, 180 Veg Capsules | | |
Supports mental abilities Most Useful Review 3 people found this helpful Selenium is essential for bolstering the immune system, fighting inflammation, and protecting cells from damage. Its antioxidant properties benefit the heart by reducing cardiovascular disease risks. Selenium supports the thyroid gland's function, shielding it from environmental harm and stimulating hormone synthesis. It also optimises gastrointestinal activities, enhances intestinal flora, and accelerates mucosal regeneration. Importantly, selenium aids in supporting mental abilities and preventing Alzheimer's disease, with studies showing that it enhances memory and concentration. Resists neurodegenerative diseases Most Useful Review This microelement is vital for the immune system, acting as a potent antioxidant that neutralises free radicals and helps avert cancer development. It protects cells from premature ageing and counters neurodegenerative diseases like Alzheimer's. A standard dosage of 200 mcg is recommended for adults. |
NOW Foods, Selenium, 100 mcg, 100 Tablets | | |
Repairs damaged nerves Most Useful Review My physician mentioned that selenium can repair damaged nerves and prevent Alzheimer's. This trace element is incredibly beneficial for overall health. Essential for immunity Most Useful Review Selenium is essential for both men and women's health, with a significant portion of the population being deficient. It boosts immunity, acts as an antioxidant, protects cells from ageing, aids Alzheimer’s prevention, helps asthmatics, and combats inflammation. Since the body cannot produce selenium, obtaining it through food is crucial. I highly recommend this reliable product. |
Jarrow Formulas, Extra Virgin Coconut Oil , 1,000 mg, 120 Softgels | | |
Alzheimer’s relief Most Useful Review 1 people found this helpful Excellent! It is ideal for the elderly, particularly in easing Alzheimer’s symptoms. I plan to reorder as the packaging matches the price well. Clear difference Most Useful Review I purchased this for my grandmother, who has Alzheimer’s, as recommended by her doctor. I noticed a clear difference when she stopped taking it; it genuinely helps, even if just a little. |
Citrucel, Methylcellulose Fiber Therapy for Irregularity, 180 Fiber Caplets | | |
Enhances memory clarity Most Useful Review 42 people found this helpful Alpha GPC greatly enhances my nootropic regimen, particularly in improving short-term memory. I incorporate it with a group of B vitamins, DMAE capsules, and magnesium. Memory issues, even in young individuals, can sometimes stem from forgetfulness due to stress. I encourage anyone facing these challenges, including those concerned about Alzheimer’s, to consider it as it has greatly benefitted me. Supports cognitive function Most Useful Review 39 people found this helpful Natural Vitamin C is a key antioxidant, vital for collagen production and immune support, with a neuroprotective effect known to aid against cognitive decline and Alzheimer’s disease. I’ve been taking it for over twenty years, finding it essential for health. On the Iherb website, there are varieties of vitamin C, with the natural forms being acerola and camu-camu, which are found in fruits and vegetables. My chosen product, Vitamin C Alive! from Nature’s Way, contains bioflavonoids that enhance absorption and is beautifully packaged. I highly recommend it! |
NOW Foods, Acetyl-L-Carnitine, 500 mg, 200 Veg Capsules | | |
Visible improvement noted Most Useful Review 1 people found this helpful Excellent! I purchased it for my 85-year-old father, who is in the early stages of Alzheimer's. After three doses, he began to speak and smile again, which was a pleasant surprise, even if the improvement was modest. We're currently using one capsule in the morning, with plans to increase it to two. Memory impairment treatment Most Useful Review 1 people found this helpful The quality is exceptional, with clean ingredients in appropriate quantities. Carnitine is known to effectively aid memory impairment and treat Alzheimer’s, as discussed by Dr. Karim. |