Vitamin K2
9.5
Normal clotting restored
Most Useful Review
A friend experienced poor blood clotting and was prescribed these vitamins. After two months of use, everything has returned to normal.
10
Essential for health
Most Useful Review
Vitamin D3 aids in calcium absorption, but it’s vitamin K2 that ensures the calcium is directed where it's needed. Without K2, calcium settles in blood vessels, which can be life-threatening. Taking both D3 and K2 together is essential for health.
Enzymes
8
Nattokinase improves stent safety
Biophysiochemically favorable, antithrombotic and pro-endothelial coordination compound nanocoating of copper (II) with protocatechuic acid & nattokinase on flow-diverting stents.
Most Relevant Research
The study aimed to address the issue of blood clot formation on neurovascular flow-diverting stents (FDSs) by exploring a new nanocoating method. This innovative coating combined copper (II), protocatechuic acid (PCA), and the enzyme nattokinase (NK) to improve the stents’ compatibility with the body and reduce the chances of thrombosis.
We found that this unique coating significantly enhanced the antithrombotic properties of the stents. The presence of nattokinase, in particular, played a crucial role in minimizing platelet and fibrinogen adhesion. This led to improved blood flow dynamics, as evidenced by longer clotting times and reduced activation of clotting factors.
Furthermore, our findings showed that the modified stents not only prevented blood clots from forming but also promoted the growth of endothelial cells, which are essential for healthy blood vessel functionality. Overall, this combination of materials and their interactions make a promising approach to enhance the safety and effectiveness of neurovascular interventions.
We found that this unique coating significantly enhanced the antithrombotic properties of the stents. The presence of nattokinase, in particular, played a crucial role in minimizing platelet and fibrinogen adhesion. This led to improved blood flow dynamics, as evidenced by longer clotting times and reduced activation of clotting factors.
Furthermore, our findings showed that the modified stents not only prevented blood clots from forming but also promoted the growth of endothelial cells, which are essential for healthy blood vessel functionality. Overall, this combination of materials and their interactions make a promising approach to enhance the safety and effectiveness of neurovascular interventions.
9.5
Improved blood circulation
Most Useful Review
I take nattokinase for blood thinning. Blood tests showed aggregation of erythrocytes and platelets, but after a month of use, there was significant improvement. I experienced heaviness in my head and legs, which gradually subsided. All tests returned to normal.
Multivitamins
9.5
Helps against blood clots
Most Useful Review
I replaced German Wobenzym with Mega-Zim, which has proven effective. I consumed four tablets daily before meals, resulting in noticeable health improvements. The enzymes assist the immune system in combatting cancer cells that are typically obscured. While Mega-Zim supports my fight against cancer, a holistic approach is crucial. I appreciate its quality and effective ingredient composition.
9.5
Decreased varicose veins
Most Useful Review
I've been taking this excellent Vitamin C for three months, and I've noticed significant improvements in my blood vessels. Varicose veins in my legs have reduced, leaving me pleasantly surprised. I highly recommend it.
Probiotics
9.5
Effective for Anaemia
Most Useful Review
These iron pills are the best I've ever tried! They didn't upset my stomach like others did, and they truly worked for my anaemia. After just six weeks on these supplements, my blood test showed a great improvement in my iron levels, all without changing my diet. I'm feeling fantastic now.
9.5
Improved symptoms
Most Useful Review
I can’t help it, girls go crazy. I passed it on to the pregnant woman, and thankfully, my blood pressure rose clearly. I often have sickle cell anaemia and during my previous pregnancy, it reached 12. After starting the new pills, I felt much better. I took three at a time and wished my doctor had recommended them earlier. The cramps in my legs have gone, and I hope to continue after birth for breastfeeding.
Vitamin E
9.5
Reduced blood pressure
Most Useful Review
I had taken Vitamin E 400 units for 30 years but stopped three years ago. My blood pressure rose to 140 systolic, which was unusual for me. After recalling the benefits of Vitamin E, I switched to the NOW brand. Within two days of resuming, my systolic dropped below 120 and has remained stable since. Vitamin E helps keep arteries healthy as we age.
9.5
Heart attack protection
Most Useful Review
The strongest antioxidant, Vitamin E at 400 IU daily, protects against heart attacks and cleanses the blood of harmful fats. This improves circulation and doesn't allow oxidation of "good cholesterol". It's essential for various metabolic processes and supports reproductive health. I notice my skin becomes smoother while taking it with fats, particularly omega acids.
Herbal Extracts
9
Improved blood circulation
Most Useful Review
I used this drug for my father's circulation issues. After two weeks of taking Ginkgo biloba and vitamins, he felt more energised and improved in terms of memory and concentration. His vein condition also enhanced. It's economical too.
9.5
Enhanced brain blood flow
Most Useful Review
I purchased this supplement due to my father's poor brain blood flow. After taking it, he stopped fainting. It worked effectively in just one dose.
Evening Primrose
9.5
Less painful periods
Most Useful Review
I am 44 and have endometriosis, resulting in heavy, prolonged periods that led to anaemia. After starting evening primrose oil, my menstrual blood loss decreased significantly, and the duration diminished to 3-4 days. I will keep taking it as I noticed a difference in my condition.
9.5
Prevented blood clots
Most Useful Review
Evening primrose oil is excellent for women's hormonal balance, alleviating PMS and menopause symptoms. It helps prevent blood clots, normalises blood pressure, and boosts skin health. It also promotes rapid healing and improves mood, offering numerous health benefits. The product quality is undoubtedly high.
Spirulina
9.5
Boosted haemoglobin levels
Most Useful Review
Spirulina is an excellent means to raise haemoglobin levels. My haemoglobin increased from 80 to 118 in just two months after using it!
9.5
Reduces blood clots
Most Useful Review
Excellent! It eliminates anaemia due to its high protein and iron content, reduces inflammation and blood clots, and improves concentration. It protects against radiation and aids liver function, enhancing overall health and preventing diseases.
Vitamin Bs
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Most Relevant Research
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
9.5
No more numbness
Most Useful Review
This is not just help; it’s a solution. My hands were occasionally numb, so the therapist sent me for a blood test for vitamin B12, which was low. After a month of taking the prescribed biological supplement, the problem disappeared and has not returned for half a year.
Garlic
9.5
Clot prevention
Most Useful Review
My father had open heart surgery in January and developed three blood clots. I started giving him this garlic supplement two months ago to maintain clean and healthy arteries along with other supplements. It has worked wonders for him, even allowing me to reduce his aspirin intake.
9.5
Pressure normalisation
Most Useful Review
Excellent garlic extract for reducing cholesterol and normalising blood pressure. It has antiviral and antibacterial properties, enhances immunity, and offers a good alternative to statins. The small, tasteless capsules are easy to swallow. A high-quality product I recommend for its effectiveness in blood pressure.
L Theanine
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Most Relevant Research
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
8.3
Normalised blood pressure
Most Useful Review
I take this product with magnesium at night to aid my sleep. My blood pressure had risen, but thanks to the theanine, magnesium, and coQ10, my arrhythmia and blood pressure have normalised. This month's health check showed excellent results. I am pleased with both the quantity and quality, and as it is a reputable brand, I will continue using it.
Cacao
10
Cleared arteries
Most Useful Review
My wife had a blood clot behind her eye revealed by an MRI. I began giving her this cacao powder daily as hot chocolate for a year. After a follow-up MRI, her blood vessel was completely normal and clear! This product has had remarkable effects, and we are exceedingly happy with the results.
9.5
Blood pressure reduction
Most Useful Review
My blood pressure has dropped! As a college student, mine was consistently above 140. After reading about its benefits for stress and lowering blood pressure, I started taking this daily. Approximately 21 grams, I measure my blood pressure three times daily, now averaging 120-110. This product has significantly improved my condition within a month.
Coenzyme Q10
9
CoQ10 reduces harmful blood clots
Coenzyme Q10 Upregulates Platelet cAMP/PKA Pathway and Attenuates Integrin αIIbβ3 Signaling and Thrombus Growth.
Most Relevant Research
We explored how coenzyme Q10 (CoQ10), a natural compound found in various foods, impacts blood clotting functions. Through a well-structured study, we utilized a randomized, double-blind, placebo-controlled trial with dyslipidemic patients, alongside in vitro tests on human platelets.
Our findings demonstrated that CoQ10 effectively reduces platelet aggregation, granule secretion, platelet spreading, and clot retraction. This means that CoQ10 can help prevent excessive blood clot formation, which is crucial for cardiovascular health.
We observed that CoQ10 works mainly by enhancing a signaling pathway involving cyclic AMP (cAMP) which ultimately diminishes the signaling of integrin αIIbβ3, a key player in platelet function. In addition, the treatment showed promising results in reducing thrombus growth in an animal model, suggesting significant in vivo benefits as well.
This study highlights the potential of CoQ10 supplementation as a protective measure for individuals at risk of cardiovascular diseases by regulating platelet-related processes involved in clotting.
Our findings demonstrated that CoQ10 effectively reduces platelet aggregation, granule secretion, platelet spreading, and clot retraction. This means that CoQ10 can help prevent excessive blood clot formation, which is crucial for cardiovascular health.
We observed that CoQ10 works mainly by enhancing a signaling pathway involving cyclic AMP (cAMP) which ultimately diminishes the signaling of integrin αIIbβ3, a key player in platelet function. In addition, the treatment showed promising results in reducing thrombus growth in an animal model, suggesting significant in vivo benefits as well.
This study highlights the potential of CoQ10 supplementation as a protective measure for individuals at risk of cardiovascular diseases by regulating platelet-related processes involved in clotting.
9.5
Normal blood pressure
Most Useful Review
My grandmother had issues with her blood pressure, both high and low. With the help of this medication, it returned to normal! I recommend purchasing it!
Calcium
9
Calcium aids rapid blood clotting
Zeolite firmly anchored regenerated cellulose aerogel for efficient and biosafe hemostasis.
Most Relevant Research
We explored the role of calcium in promoting blood coagulation using a new zeolite-embedded regenerated cellulose aerogel (Z-RCA). This innovative hemostatic agent was designed to minimize common issues seen with previous zeolite-based products, like heat-induced tissue damage and unwanted blood clotting elsewhere in the body.
Our results showed that this aerogel effectively absorbed blood while releasing calcium ions, which play a crucial role in the blood clotting process. By combining the properties of zeolite and the calcium-releasing ability of the aerogel, we found that Z-RCA not only facilitated quicker blood clotting but did so safely, with less risk of adverse effects.
In animal trials, we observed that Z-RCA stopped bleeding faster than existing options like Quikclot and notably reduced blood loss by over 62%. This combination of effectiveness and safety makes Z-RCA a promising solution for achieving efficient hemostasis during emergencies.
Our results showed that this aerogel effectively absorbed blood while releasing calcium ions, which play a crucial role in the blood clotting process. By combining the properties of zeolite and the calcium-releasing ability of the aerogel, we found that Z-RCA not only facilitated quicker blood clotting but did so safely, with less risk of adverse effects.
In animal trials, we observed that Z-RCA stopped bleeding faster than existing options like Quikclot and notably reduced blood loss by over 62%. This combination of effectiveness and safety makes Z-RCA a promising solution for achieving efficient hemostasis during emergencies.
9.5
Blood pressure stabilised
Most Useful Review
A great mix! My wife had severe blood pressure issues until I realised our previous magnesium-calcium supplement had changed, removing calcium. After switching to Now supplements, her blood pressure returned to normal. We found iHerb offered this at a better price, so we’ll continue buying from them.
Flax Seed Oil
8.8
Enhances blood circulation
Most Useful Review
Flaxseed oil is high in omega-3, second only to fish oil, with 44% to 60% concentration. It has a positive effect on the male body, boosting potency by increasing blood vessel elasticity, which improves blood circulation and supports a stable erection. It may also help normalise testosterone production, promoting male reproductive health. The presence of serotonin aids in stabilising my mood.
7.5
Aids blood clot issues
Most Useful Review
This product helps with thicker blood and is very easy to take.
Quercetin
8.3
Improved circulation
Most Useful Review
After taking three tablets, my condition improved significantly, alleviating my hyperlipidaemia and angina pectoris. I experienced headaches and shoulder stiffness, but overall, my circulation feels better. I recommend it, especially for elderly individuals dealing with blood clot risks.
9.5
Blood pressure reduction
Most Useful Review
After taking quercetin, my blood pressure finally dropped to 110/70, a level I've never achieved before. The warmth in my feet suggests improved blood circulation, leading to a lower reading.
Tumeric
9
Curcumin inhibits platelet activation
Curcumin Modulates Platelet Activation and ROS Production Induced by Amyloid Peptides: New Perspectives in Attenuating Prothrombotic Risk in Alzheimer's Disease Patients.
Most Relevant Research
We explored how curcumin, a natural compound found in turmeric, affects platelet activation specifically when stimulated by amyloid peptides associated with Alzheimer’s disease. The research aimed to determine if curcumin could help modulate these potentially harmful blood clotting responses.
Using isolated human platelets, we assessed how curcumin influences platelet aggregation and the production of reactive oxygen species. Our findings revealed that curcumin successfully suppressed platelet aggregation triggered by amyloid peptides. This suppression was linked to a decrease in critical signaling pathways involved in platelet activation.
Interestingly, while curcumin significantly inhibited responses to amyloid peptides, its effects on platelet activation induced by standard physiological triggers like thrombin and convulxin were less pronounced. Granule secretion, another aspect of platelet activation, was completely suppressed by curcumin only in response to the hemostatic stimuli, not in the presence of amyloid peptides.
Overall, it seems that curcumin may offer a targeted approach to mitigate the risk of blood clot formation in individuals suffering from Alzheimer’s disease, particularly concerning the pathological roles of amyloid peptides.
Using isolated human platelets, we assessed how curcumin influences platelet aggregation and the production of reactive oxygen species. Our findings revealed that curcumin successfully suppressed platelet aggregation triggered by amyloid peptides. This suppression was linked to a decrease in critical signaling pathways involved in platelet activation.
Interestingly, while curcumin significantly inhibited responses to amyloid peptides, its effects on platelet activation induced by standard physiological triggers like thrombin and convulxin were less pronounced. Granule secretion, another aspect of platelet activation, was completely suppressed by curcumin only in response to the hemostatic stimuli, not in the presence of amyloid peptides.
Overall, it seems that curcumin may offer a targeted approach to mitigate the risk of blood clot formation in individuals suffering from Alzheimer’s disease, particularly concerning the pathological roles of amyloid peptides.
9.5
Effective blood thinning
Most Useful Review
I wish to leave a genuine review of curcumin, six months after using it. I initially bought it for my father, who suffered severe varicose veins, and the doctors recommended surgery. We opted for curcumin instead, and he avoided surgery within a year! I took it during COVID-19 to thin my blood and noticed, after six months, that my blood thinned significantly. When I cut myself, I struggled to stop the blood from flowing for hours, which shows how effective curcumin is as a blood thinner. I even give it to my 3-year-old for colds.
L Lysine
8.3
Improves blood circulation
Most Useful Review
Lysine boosts the tone and elasticity of venous vessels, reduces tissue permeability, and enhances microcirculation, thereby helping to prevent blood clots and cholesterol plaques. As an antidepressant, it effectively alleviates headaches, fatigue, and improves concentration.
7.5
Prevents blood clots
Most Useful Review
Lysine is crucial for various bodily processes, including heart and brain function, metabolism, and skin health. It aids in treating herpes and respiratory infections. Importantly, lysine helps strengthen blood vessels and prevents atherosclerosis, potentially cleaning blood vessels and lowering the risk of blood clots. Additionally, it supports calcium absorption and guards against osteoporosis.
Red Yeast Rice
9
CoQ10 reduces harmful blood clots
Coenzyme Q10 Upregulates Platelet cAMP/PKA Pathway and Attenuates Integrin αIIbβ3 Signaling and Thrombus Growth.
Most Relevant Research
We explored how coenzyme Q10 (CoQ10), a natural compound found in various foods, impacts blood clotting functions. Through a well-structured study, we utilized a randomized, double-blind, placebo-controlled trial with dyslipidemic patients, alongside in vitro tests on human platelets.
Our findings demonstrated that CoQ10 effectively reduces platelet aggregation, granule secretion, platelet spreading, and clot retraction. This means that CoQ10 can help prevent excessive blood clot formation, which is crucial for cardiovascular health.
We observed that CoQ10 works mainly by enhancing a signaling pathway involving cyclic AMP (cAMP) which ultimately diminishes the signaling of integrin αIIbβ3, a key player in platelet function. In addition, the treatment showed promising results in reducing thrombus growth in an animal model, suggesting significant in vivo benefits as well.
This study highlights the potential of CoQ10 supplementation as a protective measure for individuals at risk of cardiovascular diseases by regulating platelet-related processes involved in clotting.
Our findings demonstrated that CoQ10 effectively reduces platelet aggregation, granule secretion, platelet spreading, and clot retraction. This means that CoQ10 can help prevent excessive blood clot formation, which is crucial for cardiovascular health.
We observed that CoQ10 works mainly by enhancing a signaling pathway involving cyclic AMP (cAMP) which ultimately diminishes the signaling of integrin αIIbβ3, a key player in platelet function. In addition, the treatment showed promising results in reducing thrombus growth in an animal model, suggesting significant in vivo benefits as well.
This study highlights the potential of CoQ10 supplementation as a protective measure for individuals at risk of cardiovascular diseases by regulating platelet-related processes involved in clotting.
9.5
Cholesterol nearly normal
Most Useful Review
I purchased this for my husband, who has high cholesterol. After three months of use, his cholesterol levels dropped nearly to normal. I recommend it to anyone with high cholesterol.
Eicosapentaenoic Acid
8
Omega-3s reduce blood clotting
Omega-3 Fatty Acids and Markers of Thrombosis in Patients with Atrial Fibrillation.
Most Relevant Research
We explored how omega-3 fatty acids, particularly eicosapentaenoic acid (EPA), influence blood clot markers in patients with atrial fibrillation (AF). Our research involved a large group of 2,373 patients, assessing the levels of D-dimer and beta-thromboglobulin (BTG), which are indicators of blood clotting activity and platelet activation.
The results showed that higher total omega-3 fatty acid levels were linked to lower D-dimer and BTG levels, which suggests a potential antithrombotic effect. Notably, the individual omega-3s, including EPA, docosahexaenoic acid (DHA), and others, generally displayed similar associations.
While EPA had a small positive relationship with BTG, DHA, DPA, and ALA were associated with lower BTG levels, indicating varied effects among these fatty acids. Overall, we found that increased omega-3 fatty acid levels could contribute to reduced activation of blood clotting mechanisms in patients with AF, highlighting the potential benefits of omega-3 intake for cardiovascular health.
The results showed that higher total omega-3 fatty acid levels were linked to lower D-dimer and BTG levels, which suggests a potential antithrombotic effect. Notably, the individual omega-3s, including EPA, docosahexaenoic acid (DHA), and others, generally displayed similar associations.
While EPA had a small positive relationship with BTG, DHA, DPA, and ALA were associated with lower BTG levels, indicating varied effects among these fatty acids. Overall, we found that increased omega-3 fatty acid levels could contribute to reduced activation of blood clotting mechanisms in patients with AF, highlighting the potential benefits of omega-3 intake for cardiovascular health.
9.5
Improvement noted
Most Useful Review
Omega-3 acids help cleanse blood vessels of excess "bad" cholesterol, preventing "cholesterol plaques". They improve blood viscosity, normalise blood pressure, increase "good" cholesterol (HDL), and strengthen vascular walls. I recommend them for maintaining healthy blood circulation.
Polygonum Cuspidatum Complex
9.5
Reduces inflammation
Most Useful Review
Resveratrol can indeed dilate blood vessels and reduce the activity of cells involved in blood clotting. It also helps to decrease inflammation and swelling.
9.5
Normalises blood pressure
Most Useful Review
I've been taking this drug for two months. I feel better, my blood pressure is normal, and I feel several years younger. I would definitely recommend it!
Vitamin D3
8
Vitamin D3 reduces platelet aggregation
1,25-Dihydroxyvitamin D3 attenuates platelet aggregation potentiated by SARS-CoV-2 spike protein via inhibiting integrin αIIbβ3 outside-in signaling.
Most Relevant Research
We focused on how 1,25-Dihydroxyvitamin D3, or vitamin D3, affects platelet aggregation, particularly in response to the SARS-CoV-2 spike protein. Individuals with COVID-19 often experience heightened blood clotting, which can lead to serious complications. Our study aimed to uncover the mechanisms behind vitamin D3’s potential benefits in reducing this risk.
Through our experiments, we discovered that vitamin D3 helped reduce platelet aggregation triggered by the spike protein. We noticed that it inhibited certain signaling pathways inside platelets, thereby curbing their ability to clump together. Even when the spike protein was introduced, vitamin D3 managed to lessen the platelet response significantly.
Interestingly, our findings suggest that vitamin D3 works by modulating a specific integrin signaling pathway, known as integrin αIIbβ3 outside-in signaling. We observed that this process involved key proteins that play a role in platelet function. Combining vitamin D3 with a Src family kinase inhibitor showed no added benefits, indicating that vitamin D3's effects might be closely tied to these signaling pathways.
Overall, our study indicates that vitamin D3 has a beneficial role in mitigating the heightened platelet activity associated with the spike protein, offering insights into its potential use as a treatment option during COVID-19.
Through our experiments, we discovered that vitamin D3 helped reduce platelet aggregation triggered by the spike protein. We noticed that it inhibited certain signaling pathways inside platelets, thereby curbing their ability to clump together. Even when the spike protein was introduced, vitamin D3 managed to lessen the platelet response significantly.
Interestingly, our findings suggest that vitamin D3 works by modulating a specific integrin signaling pathway, known as integrin αIIbβ3 outside-in signaling. We observed that this process involved key proteins that play a role in platelet function. Combining vitamin D3 with a Src family kinase inhibitor showed no added benefits, indicating that vitamin D3's effects might be closely tied to these signaling pathways.
Overall, our study indicates that vitamin D3 has a beneficial role in mitigating the heightened platelet activity associated with the spike protein, offering insights into its potential use as a treatment option during COVID-19.
9.5
Strengthened blood clotting
Most Useful Review
On my doctor’s advice, I tried this supplement and was amazed. My nails and hair transformed, and I experienced enhanced immunity and mood. Calcium is essential for healthy teeth, bones, and blood clotting. Vitamin D3 sufficiently absorbs calcium and is vital for overall health. I hope my detailed review assists you in making a choice.
Fish Oil
7
DHA may lower clotting risk
Omega-3 Fatty Acids and Markers of Thrombosis in Patients with Atrial Fibrillation.
Most Relevant Research
We set out to explore how docosahexaenoic acid, commonly known as DHA, influences blood clotting in patients with atrial fibrillation. In a detailed analysis of 2,373 individuals, we examined the relationship between total omega-3 fatty acids and specific clotting markers, D-dimer, and beta-thromboglobulin (BTG).
Our findings revealed that higher overall levels of omega-3 fatty acids were associated with lower levels of D-dimer and BTG, indicating a potential antithrombotic effect. Notably, individual omega-3s, including DHA, showed an inverse relationship with D-dimer levels, suggesting that as DHA increases, the likelihood of clot formation may decrease.
However, when it came to BTG, while DHA was linked to lower levels, the results also showed that EPA, another omega-3, had a positive correlation with BTG. This finding indicates that while DHA might play a beneficial role, the overall effects of omega-3 fatty acids on platelet activation could be complex.
In summary, the study suggests that higher levels of DHA could contribute to lower blood clotting markers, which is promising news for managing atrial fibrillation, but it also highlights the need for further investigation into the nuanced roles of different omega-3 fatty acids in blood clotting dynamics.
Our findings revealed that higher overall levels of omega-3 fatty acids were associated with lower levels of D-dimer and BTG, indicating a potential antithrombotic effect. Notably, individual omega-3s, including DHA, showed an inverse relationship with D-dimer levels, suggesting that as DHA increases, the likelihood of clot formation may decrease.
However, when it came to BTG, while DHA was linked to lower levels, the results also showed that EPA, another omega-3, had a positive correlation with BTG. This finding indicates that while DHA might play a beneficial role, the overall effects of omega-3 fatty acids on platelet activation could be complex.
In summary, the study suggests that higher levels of DHA could contribute to lower blood clotting markers, which is promising news for managing atrial fibrillation, but it also highlights the need for further investigation into the nuanced roles of different omega-3 fatty acids in blood clotting dynamics.
9.5
Cholesterol reduction
Most Useful Review
My husband, who enjoys food a bit too much, found himself with a high level of 'bad' cholesterol at 8.6. After following a doctor’s advice, including omega-3 supplements, and modifying his diet, his cholesterol dropped to 5.6 after 2.5 months! This product truly works in treating blood clots. I highly recommend it.
Omega 3
8
Omega-3s reduce blood clotting
Omega-3 Fatty Acids and Markers of Thrombosis in Patients with Atrial Fibrillation.
Most Relevant Research
We explored how omega-3 fatty acids, particularly eicosapentaenoic acid (EPA), influence blood clot markers in patients with atrial fibrillation (AF). Our research involved a large group of 2,373 patients, assessing the levels of D-dimer and beta-thromboglobulin (BTG), which are indicators of blood clotting activity and platelet activation.
The results showed that higher total omega-3 fatty acid levels were linked to lower D-dimer and BTG levels, which suggests a potential antithrombotic effect. Notably, the individual omega-3s, including EPA, docosahexaenoic acid (DHA), and others, generally displayed similar associations.
While EPA had a small positive relationship with BTG, DHA, DPA, and ALA were associated with lower BTG levels, indicating varied effects among these fatty acids. Overall, we found that increased omega-3 fatty acid levels could contribute to reduced activation of blood clotting mechanisms in patients with AF, highlighting the potential benefits of omega-3 intake for cardiovascular health.
The results showed that higher total omega-3 fatty acid levels were linked to lower D-dimer and BTG levels, which suggests a potential antithrombotic effect. Notably, the individual omega-3s, including EPA, docosahexaenoic acid (DHA), and others, generally displayed similar associations.
While EPA had a small positive relationship with BTG, DHA, DPA, and ALA were associated with lower BTG levels, indicating varied effects among these fatty acids. Overall, we found that increased omega-3 fatty acid levels could contribute to reduced activation of blood clotting mechanisms in patients with AF, highlighting the potential benefits of omega-3 intake for cardiovascular health.
8.8
Cholesterol management
Most Useful Review
Omega-3 acids "cleanse" blood vessels of "bad" cholesterol, reducing the risk of blood clots. They improve blood viscosity and normalise blood pressure while increasing "good" cholesterol. I highly recommend it.
Vitamin C
8
Scurvy-related DVT treated with vitamin C
Pediatric scurvy case report: a novel presentation with deep vein thrombosis secondary to large bilateral spontaneous iliac subperiosteal hematomas.
Most Relevant Research
We explored a unique case of a 14-year-old boy with autism who presented with deep vein thrombosis (DVT) due to large bilateral subperiosteal hematomas caused by vitamin C deficiency, known as scurvy. This rare situation is noteworthy as scurvy is typically associated with other symptoms, but here it led to an unusual complication of DVT.
During our investigation, we observed that after administering vitamin C replacement, the patient's condition improved significantly. Follow-up imaging showed that both the DVT and the hematomas resolved. This outcome suggests that vitamin C can potentially have a positive impact in cases where blood clots are related to underlying deficiencies.
However, we must clarify that while vitamin C treatment appeared beneficial in this specific situation, our findings are based on a single case. Thus, further research would be essential to understand its broader implications on DVT treatment and the role of vitamin C in blood clot scenarios.
During our investigation, we observed that after administering vitamin C replacement, the patient's condition improved significantly. Follow-up imaging showed that both the DVT and the hematomas resolved. This outcome suggests that vitamin C can potentially have a positive impact in cases where blood clots are related to underlying deficiencies.
However, we must clarify that while vitamin C treatment appeared beneficial in this specific situation, our findings are based on a single case. Thus, further research would be essential to understand its broader implications on DVT treatment and the role of vitamin C in blood clot scenarios.
9.5
Enhanced blood flow
Most Useful Review
An excellent supplement for immunity in COVID-19, quercetin can effectively prevent blood clots, reduces inflammation, and stops viruses from entering cells. I take it daily with iron, and if I feel weak or have a headache, I increase my dosage to two tablets, after which I feel much better.
Vitamins
8
Vitamin D3 reduces platelet aggregation
1,25-Dihydroxyvitamin D3 attenuates platelet aggregation potentiated by SARS-CoV-2 spike protein via inhibiting integrin αIIbβ3 outside-in signaling.
Most Relevant Research
We focused on how 1,25-Dihydroxyvitamin D3, or vitamin D3, affects platelet aggregation, particularly in response to the SARS-CoV-2 spike protein. Individuals with COVID-19 often experience heightened blood clotting, which can lead to serious complications. Our study aimed to uncover the mechanisms behind vitamin D3’s potential benefits in reducing this risk.
Through our experiments, we discovered that vitamin D3 helped reduce platelet aggregation triggered by the spike protein. We noticed that it inhibited certain signaling pathways inside platelets, thereby curbing their ability to clump together. Even when the spike protein was introduced, vitamin D3 managed to lessen the platelet response significantly.
Interestingly, our findings suggest that vitamin D3 works by modulating a specific integrin signaling pathway, known as integrin αIIbβ3 outside-in signaling. We observed that this process involved key proteins that play a role in platelet function. Combining vitamin D3 with a Src family kinase inhibitor showed no added benefits, indicating that vitamin D3's effects might be closely tied to these signaling pathways.
Overall, our study indicates that vitamin D3 has a beneficial role in mitigating the heightened platelet activity associated with the spike protein, offering insights into its potential use as a treatment option during COVID-19.
Through our experiments, we discovered that vitamin D3 helped reduce platelet aggregation triggered by the spike protein. We noticed that it inhibited certain signaling pathways inside platelets, thereby curbing their ability to clump together. Even when the spike protein was introduced, vitamin D3 managed to lessen the platelet response significantly.
Interestingly, our findings suggest that vitamin D3 works by modulating a specific integrin signaling pathway, known as integrin αIIbβ3 outside-in signaling. We observed that this process involved key proteins that play a role in platelet function. Combining vitamin D3 with a Src family kinase inhibitor showed no added benefits, indicating that vitamin D3's effects might be closely tied to these signaling pathways.
Overall, our study indicates that vitamin D3 has a beneficial role in mitigating the heightened platelet activity associated with the spike protein, offering insights into its potential use as a treatment option during COVID-19.
9.5
Improved vitamin D
Most Useful Review
Works well - my blood test numbers improved significantly within two months, indicating that it absorbs well. I recommend it to anyone seeking a good vitamin D supplement.
Iron
4
Iron's unclear role in DVT
May-Thurner Syndrome: An Unusual Case of Unilateral Severe Deep Vein Thrombosis in a Middle-Aged Women.
Most Relevant Research
We explored a 50-year-old woman who came to us with noticeable swelling and pain in her left leg lasting ten days. Upon evaluation, we found that she had deep vein thrombosis (DVT) associated with May-Thurner Syndrome (MTS), where a vein is compressed by an artery. Initially, her blood tests showed normocytic anemia, yet the tests for blood clotting disorders returned normal.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
Treatment began with anticoagulation therapy using enoxaparin, coupled with iron supplementation. While iron is typically known for helping with anemia, its specific effect on blood clot resolution in this case remains unclear. Our patient's initial treatments were expanded to include catheter-directed thrombolysis to dissolve the clot, followed by a procedure to relieve venous compression.
We observed significant success in reducing the thrombus burden and restoring blood flow post-stenting. However, we noted that the role of iron supplementation alone in treating the blood clot is ambiguous when combined with other therapies. Thus, while iron is essential for overall health and could play a supportive role, its independent effectiveness against DVT is undetermined in this scenario.
9.5
Positive improvement
Most Useful Review
For a while, I struggled with severe anaemia, receiving blood-thinning injections twice a week, and taking agents to increase my blood. Recently, I experienced dizziness and noticed my lower eyelids turning white, prompting me to start this medicine. After three weeks, my eyelid colour improved to red, which I believe indicates a significant effect.
