Selenium
8
Selenium nanoparticles show promise
We assessed the effectiveness of selenium nanoparticles (SeNPs) derived from the plant Indigofera aspalathoides for treating breast cancer. Through innovative green synthesis methods utilizing the plant's extract, we created nanoparticles that were carefully characterized to confirm their stability and size. This is an important step since the size and structure of nanoparticles can greatly influence their effectiveness in medical applications.
We found that these SeNPs displayed notable antioxidant properties, which can be crucial in combating oxidative stress associated with cancer. In our experiments, the SeNPs achieved high levels of DPPH and hydroxyl radical scavenging, significantly surpassing the antioxidant activity of the extract on its own.
Notably, when we tested the cytotoxic effects on the MCF-7 breast cancer cell line, we observed promising results. The nanoparticles exhibited a protective effect on HepG2 liver cells, promoting cell viability at certain concentrations. While moderate doses of the SeNPs showed excellent results, higher doses did present some cytotoxicity.
Overall, our findings highlight the potential of I. aspalathoides-derived SeNPs as a promising avenue in nanomedicine for addressing not just oxidative stress, but also for supporting liver health as it relates to breast cancer treatment.
We found that these SeNPs displayed notable antioxidant properties, which can be crucial in combating oxidative stress associated with cancer. In our experiments, the SeNPs achieved high levels of DPPH and hydroxyl radical scavenging, significantly surpassing the antioxidant activity of the extract on its own.
Notably, when we tested the cytotoxic effects on the MCF-7 breast cancer cell line, we observed promising results. The nanoparticles exhibited a protective effect on HepG2 liver cells, promoting cell viability at certain concentrations. While moderate doses of the SeNPs showed excellent results, higher doses did present some cytotoxicity.
Overall, our findings highlight the potential of I. aspalathoides-derived SeNPs as a promising avenue in nanomedicine for addressing not just oxidative stress, but also for supporting liver health as it relates to breast cancer treatment.
9
Effective skin remedy
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14 people found this helpful
This brand and dosage are fantastic! After a period of late nights and sleep deprivation, I had a flare-up of skin issues. Upon taking a blend of vitamins and this selenium supplement, I noticed significant improvement. The swollen, itchy skin reduced drastically within two days. It's far more effective than Western antiviral medicines! Now, it's a staple in my home for daily intake. If you have hepatitis B, I recommend combining selenium with natural vitamin E and silymarin to protect your liver and lower the risk of liver cancer.
Turmeric Curcumin
8
We explored the effects of curcumin, a compound derived from turmeric, on breast cancer treatment through carefully designed experiments. The study focused on enhancing curcumin's delivery and effectiveness using nanoparticles. These nanoparticles help overcome curcumin's poor solubility and low bioavailability, which can limit its anti-cancer potential.
By using a specific method to create curcumin-loaded nanoparticles, we created a formulation that helps deliver curcumin more effectively into cancer cells. When tested on BT-474 human breast cancer cells, the curcumin nanoparticles showed better cytotoxic responses compared to free curcumin. Notably, the nanoparticles demonstrated improved effectiveness when exposed to light, supporting their use in photodynamic therapy.
Overall, our findings suggest that curcumin, when enhanced through nanoparticle technology, could significantly improve treatment options for breast cancer. This study opens the door for further investigation into how turmeric and similar compounds can be maximized for therapeutic use against cancer.
By using a specific method to create curcumin-loaded nanoparticles, we created a formulation that helps deliver curcumin more effectively into cancer cells. When tested on BT-474 human breast cancer cells, the curcumin nanoparticles showed better cytotoxic responses compared to free curcumin. Notably, the nanoparticles demonstrated improved effectiveness when exposed to light, supporting their use in photodynamic therapy.
Overall, our findings suggest that curcumin, when enhanced through nanoparticle technology, could significantly improve treatment options for breast cancer. This study opens the door for further investigation into how turmeric and similar compounds can be maximized for therapeutic use against cancer.
9
Remission achieved
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103 people found this helpful
I have been taking 2 grams (4 capsules) of curcumin daily since my stage 4 breast cancer diagnosis a year ago. Remarkably, I went into remission within three months, and all tumours have disappeared. I’ve been in remission for eight months with no evidence of disease.
Folic Acid
7
Dual-targeted Dox delivery assessed
We investigated the impact of using folate, in conjunction with a specific peptide known as cRGD, in a targeted delivery system for the chemotherapy drug doxorubicin (Dox) in breast cancer treatment. Our approach involved a composition called NPh-Dox-cRGD-Fol(2.0), which effectively combined both targeting agents with the same linker length.
The results revealed that the dual-vector system significantly improved the internalization and accumulation of doxorubicin in breast cancer cells that express the folate receptor as well as integrin αvβ3. In fact, when we compared this dual approach to the single-vector system featuring only folate, the dual composition showed enhanced release rates of the drug in various pH conditions, particularly in acidic environments typical of tumor tissues.
However, it is important to note that we did not isolate the effects of folate alone in this study, which makes it difficult to pinpoint its individual contribution. While the dual-vector system was effective, in experiments with a different breast cancer cell line that expresses only the folate receptor, we noted similar outcomes when using compositions just containing folate. This highlights that while folate can play a role in drug delivery, its exclusive impact could not be firmly established.
We also observed varying results with normal cells, indicating that the targeted compositions did not demonstrate a significant difference in drug uptake compared to free doxorubicin. Ultimately, while we saw encouraging results with the dual-targeted approach, we must clarify that the specific benefits of folate on its own were not conclusively determined from our findings.
The results revealed that the dual-vector system significantly improved the internalization and accumulation of doxorubicin in breast cancer cells that express the folate receptor as well as integrin αvβ3. In fact, when we compared this dual approach to the single-vector system featuring only folate, the dual composition showed enhanced release rates of the drug in various pH conditions, particularly in acidic environments typical of tumor tissues.
However, it is important to note that we did not isolate the effects of folate alone in this study, which makes it difficult to pinpoint its individual contribution. While the dual-vector system was effective, in experiments with a different breast cancer cell line that expresses only the folate receptor, we noted similar outcomes when using compositions just containing folate. This highlights that while folate can play a role in drug delivery, its exclusive impact could not be firmly established.
We also observed varying results with normal cells, indicating that the targeted compositions did not demonstrate a significant difference in drug uptake compared to free doxorubicin. Ultimately, while we saw encouraging results with the dual-targeted approach, we must clarify that the specific benefits of folate on its own were not conclusively determined from our findings.
7.5
Cancer protection
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It's important to consume folic acid not just before and during pregnancy, as it may protect against various cancers, including breast cancer.
Kelp
7
We examined the effects of fucoidan from kelp on triple-negative breast cancer cells. Our experiments revealed that fucoidan exhibits some ability to kill cancer cells and promote apoptosis, a process that encourages cell death. While it shows promise, the amount needed for effectiveness is considerably higher than traditional treatments.
We also noticed that fucoidan works through various mechanisms to induce apoptosis, indicating its potential in cancer therapy. Nevertheless, further research is essential to fully understand its effectiveness and its broader applications in treating breast cancer.
We also noticed that fucoidan works through various mechanisms to induce apoptosis, indicating its potential in cancer therapy. Nevertheless, further research is essential to fully understand its effectiveness and its broader applications in treating breast cancer.
9
Breast pain relief
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1 people found this helpful
After taking this with NOW's evening primrose oil, my breast pain disappeared completely. It's as if I never had the pain, and I had forgotten it was ever a symptom.
Omega 3 Fish Oil
7
Eicosapentaenoic acid impacts breast cancer
We conducted a well-designed study to explore the effects of eicosapentaenoic acid (EPA) combined with docosahexaenoic acid (DHA) on women who have survived estrogen and progesterone receptor-negative (ERPR-) breast cancer. This specific type of breast cancer is known to be more influenced by dietary fats, making our investigation both timely and relevant.
Over the course of 12 months, we administered either approximately 1 or 5 grams of EPA and DHA daily to participants who had recently completed standard treatment for ERPR- breast cancer. We collected blood and breast adipose tissue samples at regular intervals to analyze the levels of fatty acids, oxylipins, and examine changes in DNA methylation patterns.
Our findings revealed that higher doses of EPA and DHA significantly increased levels of fatty acids and their beneficial metabolites in breast tissue. Moreover, these changes were associated with distinct DNA methylation profiles, shedding light on potential new pathways through which these fatty acids could help reduce the risk of ERPR- breast cancer recurrence.
This research suggests that incorporating n-3 polyunsaturated fatty acids, like EPA and DHA, into the diets of breast cancer survivors may have both metabolic and epigenetic benefits, potentially playing a role in preventing the progression of this aggressive cancer subtype.
However, it’s worth noting that our study mixed EPA and DHA, making it challenging to attribute effects solely to EPA. Nevertheless, these promising results point to the importance of dietary fats in breast cancer survivorship.
Over the course of 12 months, we administered either approximately 1 or 5 grams of EPA and DHA daily to participants who had recently completed standard treatment for ERPR- breast cancer. We collected blood and breast adipose tissue samples at regular intervals to analyze the levels of fatty acids, oxylipins, and examine changes in DNA methylation patterns.
Our findings revealed that higher doses of EPA and DHA significantly increased levels of fatty acids and their beneficial metabolites in breast tissue. Moreover, these changes were associated with distinct DNA methylation profiles, shedding light on potential new pathways through which these fatty acids could help reduce the risk of ERPR- breast cancer recurrence.
This research suggests that incorporating n-3 polyunsaturated fatty acids, like EPA and DHA, into the diets of breast cancer survivors may have both metabolic and epigenetic benefits, potentially playing a role in preventing the progression of this aggressive cancer subtype.
However, it’s worth noting that our study mixed EPA and DHA, making it challenging to attribute effects solely to EPA. Nevertheless, these promising results point to the importance of dietary fats in breast cancer survivorship.
7.5
Helps breast cancer prevention
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The quality is beautiful, and the Omega-3 ingredients are beneficial. Omega-3 fatty acids, especially DHA, are crucial for health, maintaining brain health, protecting the retina, and enhancing heart health by lowering triglycerides. Studies confirm that Omega-3s may lower the risk of breast cancer and high blood pressure, among other conditions. The taste is normal.
Lecithin
7
Soy lecithin shows anticancer potential
This study looked at how a new soy lecithin-based delivery system could help fight breast cancer. Known as BLSP, it showed promising cytotoxic effects against MCF-7 breast cancer cells.
By utilizing advanced techniques, researchers confirmed the formulation can release its active components in a controlled manner. Moreover, the results indicate that BLSP may trigger important cellular processes that could enhance cancer treatment.
Importantly, the safety tests suggest it poses low toxicity in this context. Overall, BLSP appears to be a hopeful option for delivering treatment for both breast and cervical cancers.
By utilizing advanced techniques, researchers confirmed the formulation can release its active components in a controlled manner. Moreover, the results indicate that BLSP may trigger important cellular processes that could enhance cancer treatment.
Importantly, the safety tests suggest it poses low toxicity in this context. Overall, BLSP appears to be a hopeful option for delivering treatment for both breast and cervical cancers.
9
Improved milk flow
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1 people found this helpful
After trying it for a few days, I placed another bottle in my cart. I can't imagine my breastfeeding journey without it; my milk flow is much better now, and I have fewer clogged ducts.
Vitamin D
8
We examined the relationship between vitamin D intake and breast cancer, delving into how this vitamin may play a role in prevention and management. The findings suggest that vitamin D may have a protective effect, potentially lowering the risk of developing breast cancer.
While we found a notable connection, it’s important to recognize that most of the existing evidence comes from observational studies. This means we can identify associations but cannot definitively say that vitamin D causes these effects.
Additionally, there are several complexities in studying vitamin D, such as varying metabolism and differences in study designs, which make drawing firm conclusions challenging.
Although the research provides intriguing insights, more rigorous studies are necessary to truly clarify how vitamin D could be integrated into breast cancer care moving forward.
While we found a notable connection, it’s important to recognize that most of the existing evidence comes from observational studies. This means we can identify associations but cannot definitively say that vitamin D causes these effects.
Additionally, there are several complexities in studying vitamin D, such as varying metabolism and differences in study designs, which make drawing firm conclusions challenging.
Although the research provides intriguing insights, more rigorous studies are necessary to truly clarify how vitamin D could be integrated into breast cancer care moving forward.
7.5
Fights cancer risks
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12 people found this helpful
The lanolin composition is good. No vitamin impacts health like Vitamin D. Research shows that it may prevent SARS and lowers risks of various cancers, including breast cancer. I bought Vitamin D3 to take during the pandemic. The tablets are easy to swallow, ideally taken with fatty foods. I take 5000 units.
Evening Primrose Oil
5
Evening primrose oil shows limited effects
We conducted a randomized, double-blind, controlled trial to explore the effects of fish oil and evening primrose oil (EPO) on breast cancer patients undergoing chemotherapy. Over 12 weeks, participants received either the oil supplements or a placebo.
While we noted improvements in fatty acid profiles in the treatment group, the study showed no significant changes in inflammatory markers between the two groups. Despite a decrease in IL-6 levels in the intervention group, there was no major benefit observed overall.
Ultimately, our findings suggest that while this supplementation can help with lipid metabolism, it does not deliver significant anti-inflammatory effects for breast cancer patients undergoing chemotherapy.
While we noted improvements in fatty acid profiles in the treatment group, the study showed no significant changes in inflammatory markers between the two groups. Despite a decrease in IL-6 levels in the intervention group, there was no major benefit observed overall.
Ultimately, our findings suggest that while this supplementation can help with lipid metabolism, it does not deliver significant anti-inflammatory effects for breast cancer patients undergoing chemotherapy.
9
Eliminates PMS symptoms
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34 people found this helpful
I tried this superhero butter out of curiosity, and it completely eradicated my PMS symptoms for months! Previously, I experienced breast soreness for 10 days prior to my period, but now I hardly notice any symptoms. I forget about my monthly cycle entirely—no pain or discomfort at all! I might take it a few times a year. Thanks, iHerb! I’ll definitely remember it for when I eventually give birth!
Enzymes
7
We explored the effects of coenzyme Q10 (CoQ) and its associated enzyme, UBIAD1, on breast cancer progression. Our study revealed that CoQ plays an important role in influencing the mechanical properties of cancer cells, particularly their stiffness. Interestingly, both CoQ and UBIAD1 were shown to increase the fluidity of the cell membrane, which resulted in stiffer cancer cells.
Additionally, we found that these factors could disrupt key signaling mechanisms within the extracellular matrix (ECM), leading to reduced resistance to ferroptosis, a type of cell death that is crucial in cancer treatment settings. Through analyses involving human patients and mouse models, we discovered that a loss of UBIAD1 is linked to breast cancer development and progression. This implies that maintaining UBIAD1 levels could potentially limit the survival of circulating tumor cells and prevent metastasis, particularly to the lungs.
Overall, our findings shed light on the potential of CoQ and UBIAD1 as targets for developing new therapeutic strategies to assist breast cancer patients, especially those facing a poor prognosis.
Additionally, we found that these factors could disrupt key signaling mechanisms within the extracellular matrix (ECM), leading to reduced resistance to ferroptosis, a type of cell death that is crucial in cancer treatment settings. Through analyses involving human patients and mouse models, we discovered that a loss of UBIAD1 is linked to breast cancer development and progression. This implies that maintaining UBIAD1 levels could potentially limit the survival of circulating tumor cells and prevent metastasis, particularly to the lungs.
Overall, our findings shed light on the potential of CoQ and UBIAD1 as targets for developing new therapeutic strategies to assist breast cancer patients, especially those facing a poor prognosis.
7.5
Raises morale
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29 people found this helpful
I was advised to take this by Dr Mohamed Al-Fayed while dealing with my breast cancer diagnosis. It has significantly raised my morale during a difficult time of tumour removal. I believe it's a powerful antioxidant, and I've been encouraged after speaking with medical professionals about its benefits.
Multivitamins
9
Supports cancer treatment
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16 people found this helpful
I replaced the German Wobenzym with Mega-Zim for my breast cancer treatment. It has worked brilliantly, even better in terms of enzyme content! One can lasted me 10 days using high doses, needing three cans each month. Mega-Zim helps the immune system recognise cancer cells by breaking down their protective protein coating, allowing the body to fight back. I took it before meals with warm water, satisfied with the results and quality. I'm 56 years old, and I highly recommend this.
9
Eases symptoms
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6 people found this helpful
After being diagnosed with multiple fibroadenomas, I turned to these enzymes for my breast cancer concerns. Remarkably, the swelling in both breasts has reduced, and I can no longer feel the cysts. I plan to have an ultrasound soon, but I am pleased with the improvement.
Quercetin
9
Pain reduction
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25 people found this helpful
I chose this quercetin product as it was your top seller. I'm using this flavonoid with others to tackle my incurable advanced breast cancer. The pain in my legs and feet is definitely lessening, which is wonderful. My oncologist had expected I would not survive past early 2020. I'm extremely pleased with the effects of this product.
9
Jarrow recommendation
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17 people found this helpful
My oncologist recommended the Jarrow brand for my breast cancer treatment, stating it accurately reflects what’s on its label.
Melatonin
9
Safe for sleep
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I have taken melatonin every night for years and would never travel without it. Recommended by my doctor after a bout of breast cancer 20 years ago, I find it safe and non-addictive.
7.5
Promotes smooth sleep
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1 people found this helpful
I struggled with sleep but found that this really helps me fall asleep smoothly. Although not approved in Japan, I read that melatonin may inhibit cancer progression, so I began taking it three years ago during my colon cancer treatment.
Alfalfa
8
Increased breast milk
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1 people found this helpful
I purchased this to enhance milk production while breastfeeding, and it has been tremendously helpful!
9
Breast milk boost
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I highly recommend this product, as it significantly helped me with milk production while breastfeeding.
Vitamin E
9
Cancer prevention benefits
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1 people found this helpful
I consistently take Vitamin E due to its benefits, especially for women over 40. It aids in cleansing the body, boosts immunity, slows ageing, restores cells, and reduces the risk of breast cancer.
9
Treats breast diseases
Most Useful Review
This Vitamin E is high quality, and Solgar uses glass packaging, which is a significant benefit! My doctor prescribed it for mastopathy, as it's vital for gynecological and breast diseases.
Resveratrol
9
Therapeutic properties noted
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1 people found this helpful
Resveratrol is a natural compound that has been thoroughly researched for its antioxidant and free radical scavenging effects. It has anti-cancer properties, functioning as both a therapeutic and chemopreventive agent.
7.5
Stabilised estrogen levels
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1 people found this helpful
Resveratrol is recognised as an antioxidant promoting youthful vitality, possessing anti-inflammatory and anti-carcinogenic attributes. At 74, I take it (1 capsule each morning with food) to stabilise estrogen levels and reduce the risk of breast cancer, especially as I have mastopathy. I've noticed some improvement in my vision from long hours at the computer. I highly recommend it.
Broccoli
9
Supports mastopathy treatment
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1 people found this helpful
It’s effective—I’ve used it with a combination aimed at breast issues, and it’s greatly assisted with mastopathy. Highly recommended for those suffering from this condition.
9
Beneficial for breast cancer
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1 people found this helpful
The antioxidant properties are beneficial, especially when combined with breast-related supplements.
Sweet Almond
9
No more stretch marks
Most Useful Review
3 people found this helpful
It’s simply perfect! This wonderful natural oil is for entire body use. I have purchased it multiple times, both for myself and as gifts. The first aspect I want to highlight is its quality and natural composition. I recommend using it regularly during pregnancy to prevent stretch marks on the tummy and breasts. The pleasant, mild scent and its effectiveness on wet skin avoiding greasiness make it fantastic for dry skin as well. Due to its natural ingredients, it does not cause allergic reactions, making it safe without a doctor's prescription. I’m grateful not to have stretch marks post-pregnancy!
7.5
Skin elasticity improvement
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7 people found this helpful
Greetings from Ukraine! I adore this wonderful oil, which I have used previously to moisturise the skin of my abdomen and breasts following childbirth. The result is that my skin becomes more elastic and well-groomed each day. With no fragrance and a good composition, the large packaging lasts quite a while. Treat yourself; I wholeheartedly recommend I Herb products!