Potassium
9.5
Essential potassium benefits
Most Useful Review
Potassium is crucial for optimal energy and nerve health, and it significantly helps prevent cardiovascular diseases. I found remarkable results using potassium—it aids in regulating blood pressure and improving oxygen supply to the brain. After using it, I noticed positive changes, particularly for my allergic child. It's a vital mineral, and I recommend it for everyone seeking better health. If my feedback was useful, please click “Yes”.
9.5
Alleviates stress impacts
Most Useful Review
I chose this potassium supplement and experienced positive changes in my health. Sleep has improved, and stress levels have decreased, which is vital for anyone facing cardiovascular issues. The quality is excellent and I recommend maintaining sufficient potassium levels to prevent health problems. Wishing everyone good health!
Nattokinase
9.5
Relieved arrhythmia symptoms
Most Useful Review
Nattokinase is a unique enzyme essential for preventing various diseases, significantly aiding heart function. It improves blood circulation, dissolves blood clots, reduces the risk of cardiovascular disease, and promotes healthy cholesterol levels. After experiencing severe symptoms, I took nattokinase and felt improvements with each pill, eventually reducing my dosage as I felt better.
9.5
Effective thrombolytic therapy
Most Useful Review
Nattokinase is a remarkable enzyme used for cardiovascular problems, especially in Asia, and is gaining recognition in the West for its anticoagulant properties. It shows promise in treating cardiovascular diseases and is a reliable choice for effective and economical treatment.
Garlic
9.5
Strengthens immunity
Most Useful Review
I took garlic extract to support my cardiovascular health. After having stents placed in my coronary arteries and a brain aneurysm, I can confidently say this product is excellent. It offers anti-inflammatory and bactericidal effects, boosts the immune system, and normalises metabolism.
9.5
Regulates cholesterol
Most Useful Review
I used garlic extract to aid my cardiovascular health. After having stents, I believe this supplement is outstanding. Despite long-term statin use, my cholesterol remained unchanged until I started this product. Within six months, my cholesterol returned to normal, and now even my family is using it.
Ubiquinol
9
Ubiquinol reduces HF mortality, boosts exercise
Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysis.
Most Relevant Research
We aimed to understand how ubiquinol, also known as coenzyme Q10 (CoQ-10), can impact those suffering from heart failure (HF). To do this, we conducted a thorough review of existing studies, searching databases like MEDLINE and the Cochrane Library for relevant literature.
Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.
Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.
In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.
Throughout our evaluation, we focused on key outcomes: whether CoQ-10 could reduce HF-related mortality, improve patients' exercise capacity, and affect the left ventricular ejection fraction (LVEF). Our analysis included findings from 16 different studies that provided intriguing insights.
Notably, we observed that CoQ-10 was effective in reducing HF-related mortality by an impressive 40%. Additionally, patients taking CoQ-10 reported enhanced exercise capacity, which is crucial for improving their quality of life. However, when it came to the left ventricular ejection fraction, the results were less clear; we found no significant difference, though we acknowledge that further research is needed to fully explore its potential effects in this area.
In summary, CoQ-10 shows promise in supporting heart failure patients by reducing mortality and boosting exercise capacity, but its role related to LVEF still warrants additional exploration.
8.8
Supports cardiovascular health
Most Useful Review
Ubiquinol strengthens the cardiovascular system. I previously experienced hypertension and arrhythmia.
Polygonum Cuspidatum Complex
9.5
Prevents ageing
Most Useful Review
The primary function of this drug is to prevent premature ageing of the cardiovascular system. It performs excellently in this regard, earning five stars.
9.5
Longevity benefits
Most Useful Review
Scientists suggest that resveratrol activates longevity genes and may prevent Alzheimer’s, reduce joint pain, and improve inflammatory bowel disease. It’s beneficial for cardiovascular disease and diabetes, making it a valuable product to purchase.
Multivitamins
9.5
Normalises pressure
Most Useful Review
Taking these B vitamins has significantly improved my health. After a month, leg pain disappeared and my sensory issues in fingers and toes were resolved. I recommend taking it alongside magnesium for better results in managing stress and blood pressure. During pregnancy, it helped keep my blood pressure stable. I’m very pleased and will order more.
9
Supports immunity
Most Useful Review
Vitamin B is crucial for brain and nerve function. It aids in metabolism and energy production, and deficiencies can lead to symptoms like mood swings and immune issues. It's important to maintain adequate levels to support various bodily functions.
Vitamin K2
8.3
Vascular health
Most Useful Review
Vitamin K2 contributes to vascular and heart health by preventing calcium from being incorrectly absorbed, thus lowering the risks associated with coronary heart disease.
8.8
Cardiovascular health
Most Useful Review
This delicious vitamin K complex is essential for maintaining cardiovascular health. There are no side effects.
Protein
9
Tailored nutrition improves heart health
Individualized Nutritional Support Improves Cardiac Function and Nutritional Status of Elderly Heart Failure Patients.
Most Relevant Research
We explored how tailored nutritional support can impact elderly patients suffering from chronic heart failure (CHF). In a study involving 102 hospitalized patients, we divided participants into two groups: one received standard care, while the other benefited from specialized nutritional support provided by a trained nursing team.
As we analyzed the results, it became clear that both groups saw improvements in common health indicators like albumin, hemoglobin, and protein levels. However, the experimental group, which received individualized nutrition support, achieved significantly better results. Notably, improvements in heart function—including left ventricular ejection fraction—were more pronounced within this group.
Importantly, we also noted that the experimental group exhibited reductions in harmful inflammatory markers and reported better quality of life and greater satisfaction with nursing care. While our focus was broader than just protein's effect, the study highlights the value of a comprehensive nutritional approach, suggesting that fostering good nutrition plays an essential role in managing heart health among the elderly.
As we analyzed the results, it became clear that both groups saw improvements in common health indicators like albumin, hemoglobin, and protein levels. However, the experimental group, which received individualized nutrition support, achieved significantly better results. Notably, improvements in heart function—including left ventricular ejection fraction—were more pronounced within this group.
Importantly, we also noted that the experimental group exhibited reductions in harmful inflammatory markers and reported better quality of life and greater satisfaction with nursing care. While our focus was broader than just protein's effect, the study highlights the value of a comprehensive nutritional approach, suggesting that fostering good nutrition plays an essential role in managing heart health among the elderly.
9.5
Strengthens immunity
Most Useful Review
I ordered pumpkin seeds for the first time. They are excellent quality, not too large, but clean and perfect. The whole family enjoys them, and I provide them daily due to their valuable composition. Pumpkin seeds contain essential nutrients that can help fight cancer and boost immunity, making them beneficial for treating cardiovascular disease. Regular consumption aids the gastrointestinal system, lowers blood pressure, and strengthens blood vessels. The numerous benefits are significant, and I will certainly reorder them. Wishing everyone good health!
Quercetin
9.5
Cardiovascular support
Most Useful Review
I ordered this long ago but only recently tried it. My endocrinologist suggested bromelain for better food absorption and anti-inflammatory activity. Quercetin strengthens blood vessels and supports the cardiovascular system. I take one to two capsules twice daily with food, and the jar lasts long enough for a complete course.
9.5
Preventing disease
Most Useful Review
This is an excellent supplement for heart health. We use it for both my mother and grandmother, especially after Covid-19, as it's crucial for vascular recovery. Quercetin is a powerful antioxidant, protecting cell membranes and helping prevent cardiovascular disease.
Coconut Oil
9.5
Helps thyroid function
Most Useful Review
Protocol PCOS and AIT. Coconut oil is a beneficial remedy for autoimmune thyroiditis, aiding the immune system and the thyroid. It has anti-inflammatory properties, reducing antibodies and inflammation, thereby supporting cardiovascular health. After extensive studies, 65% of women with PCOS were found to have AIT. Coconut oil promotes skin hydration and healthy hair while being a part of my daily routine. I prefer the oil in capsules for travel and recommend it for overall well-being.
9.5
Effective cardiovascular support
Most Useful Review
Fantastic for my cardiovascular health! The Now brand has always been reliable. The softgels are easy to swallow and work effectively. I highly recommend them!
Vitamin B Complex
9.5
Energy boost
Most Useful Review
Thank you, iHerb. I am quite pleased with the complex! It genuinely provides strength and energy. I usually take one capsule, but after a stressful day, I took another one later, and it revitalised me. Everyone in my family has benefitted, especially with the easily digestible Vitamin B12. A lack of B12 can lead to significant issues, including nervous system disorders. Thus, this complex is crucial for maintaining health, particularly for combating cardiovascular disease.
9.5
Reduced migraine symptoms
Most Useful Review
Trims my migraine attacks significantly. I have a classic migraine and was sceptical about B-Complex being effective, but the results were striking: my seizure frequency dropped. When I stopped taking it, my attacks increased. With this complex, I consume one pack of triptans a month instead of six to seven.
L Lysine
9.5
Strong antiviral effect
Most Useful Review
Excellent antiviral and immunomodulating agent. L-Lysine boasts a more than 95% effectiveness in treating viral diseases compared to 50-80% for antiviral drugs, regardless of the disease stage. Even in cases where it’s less effective, it prevents disease progression and enhances overall well-being. Additionally, it improves brain function and increases stress resilience.
9.5
Boosts immunity
Most Useful Review
Very strong antiviral effect. L-Lysine outperforms many antiviral medications. It halts disease progression and enhances overall well-being. It also improves brain function and may support cardiovascular health. Easy to take without an unpleasant taste and increases appetite.
Vitamins
7
Vitamin D3's influence on CVD risk
Perirenal fat differs in patients with chronic kidney disease receiving different vitamin D-based treatments: a preliminary study.
Most Relevant Research
We explored how different vitamin D treatments may influence cardiovascular disease (CVD) risk among patients with chronic kidney disease (CKD). Our observational study included 83 CKD patients who were treated with vitamin D or its analogs and had varying histories of CVD. By measuring the thickness of perirenal adipose tissue (PAT) and assessing clinical parameters, we aimed to uncover any links between vitamin D treatment and cardiovascular health.
We found that patients with a history of CVD showed thicker PAT compared to those without such a history. Interestingly, our comparisons among patients receiving different forms of vitamin D revealed that those treated with paricalcitol had less PAT accumulation than those on cholecalciferol or calcitriol. This suggests that the type of vitamin D treatment may play a role in managing CVD risk in CKD patients.
Although our findings indicate differences in PAT thickness related to vitamin D treatment, we did not conduct a controlled trial that would allow us to claim a definitive benefit of vitamin D3 alone on cardiovascular health. It appears that further investigation is necessary to clarify these relationships and understand the mechanisms at play.
We found that patients with a history of CVD showed thicker PAT compared to those without such a history. Interestingly, our comparisons among patients receiving different forms of vitamin D revealed that those treated with paricalcitol had less PAT accumulation than those on cholecalciferol or calcitriol. This suggests that the type of vitamin D treatment may play a role in managing CVD risk in CKD patients.
Although our findings indicate differences in PAT thickness related to vitamin D treatment, we did not conduct a controlled trial that would allow us to claim a definitive benefit of vitamin D3 alone on cardiovascular health. It appears that further investigation is necessary to clarify these relationships and understand the mechanisms at play.
9.5
Boosts immunity
Most Useful Review
This supplement strengthens immunity significantly; one capsule provides a full day's worth of vitamin D, essential for our health. I trust NOW FOODS for the quality it provides. The combination with vitamin K2 improves the efficiency of vitamin D absorption, supporting bone health and reducing cardiovascular disease risk.
Vitamin E
9.5
Strengthens immunity
Most Useful Review
Excellent strength, price, and quality! It helps combat viral diseases and strengthens the immune system. Highly recommended!
9.5
Normalised antibodies
Most Useful Review
With my autoimmune thyroid disease and a recognised selenium deficiency, I've noticed significant improvements. After my first bottle, my antibodies normalised, much to my doctor's surprise. The addition of Vitamin E also provides excellent antioxidant support. I wholeheartedly recommend it!
9.5
Improves heart function
Most Useful Review
Fish oil is highly beneficial and should be consumed daily. It improves blood pressure, vision, brain function, skin condition, and strengthens immunity. Most importantly, it boosts cardiovascular health. I recommend taking three capsules a day; there’s no unpleasant smell.
8.3
Promotes health benefits
Most Useful Review
Amazing! It promotes cardiovascular health and cognitive wellbeing, effectively maintaining triglyceride, HDL, and LDL cholesterol levels. It includes heart-healthy Mediterranean sesame and olive extracts and features IFOS™ certified anchovies that are sustainably sourced from the South Pacific coast of Chile.
Herbal Extracts
9.5
Boosts circulation
Most Useful Review
We have purchased it multiple times due to its excellent quality. It increases energy, sharpens cognitive function, and enhances memory. Ginkgo Biloba improves blood circulation, which may help mitigate the risks of cardiovascular disease and other serious health concerns.
9.5
Improves clarity
Most Useful Review
I bought this for my mother, who has multiple sclerosis, to enhance her memory and improve brain blood circulation. After a month, she reports clearer thinking compared to a similar medication. The formulation is efficient, requiring just one pill daily, making it safe for regular use.
Coenzyme Q10
9
CoQ10 protects against heart injury
Coenzyme Q10 and its liposomal form prevent copper cardiotoxicity by attenuating oxidative stress, TLR-4/NF-κB signaling and necroptosis in rats.
Most Relevant Research
We explored the protective effects of Coenzyme Q10 (CoQ10) and its liposomal form on heart health, particularly in response to copper toxicity caused by copper sulfate (CuSO4). In this study, rats received daily doses of CuSO4 to induce heart injury, while some were also treated with CoQ10 or L-CoQ10 to see if these supplements could mitigate the damage.
The results showed that CuSO4 led to elevated cardiac injury markers and increased oxidative stress, which is known to contribute to heart issues. However, the inclusion of CoQ10 and L-CoQ10 helped lower the levels of harmful markers, improve antioxidant capacity, and reduce inflammation. These supplements effectively restored balance and reduced signs of heart injury, highlighting their potential cardioprotective roles.
Overall, the findings suggest that CoQ10 could serve as a valuable defense for individuals at risk of copper toxicity, reinforcing its relevance in supporting cardiovascular health.
The results showed that CuSO4 led to elevated cardiac injury markers and increased oxidative stress, which is known to contribute to heart issues. However, the inclusion of CoQ10 and L-CoQ10 helped lower the levels of harmful markers, improve antioxidant capacity, and reduce inflammation. These supplements effectively restored balance and reduced signs of heart injury, highlighting their potential cardioprotective roles.
Overall, the findings suggest that CoQ10 could serve as a valuable defense for individuals at risk of copper toxicity, reinforcing its relevance in supporting cardiovascular health.
9.5
Improved health
Most Useful Review
My journey with Coenzyme Q10 began two years ago after my mother's heart attack. She suffered from cardiovascular disease and had many related complications. After starting CoQ10, along with other supplements, her arrhythmia attacks ceased within five months. We've now been taking it for two years. I noticed a significant boost in my energy and overall performance since starting CoQ10 myself. It appears to enhance heart health and has notably improved our well-being, making it a vital addition to our health regimen.
Cranberry
9.5
Supports heart health
Most Useful Review
Cranberries are rich in vitamins and plant compounds that support urinary tract health and can help reduce the risk of cardiovascular disease. They also boast antioxidants that combat chronic inflammation and protect cells from malignant cell changes. Including cranberries in my diet has helped lower stomach disease incidence by inhibiting Helicobacter pylori.
8.8
Prevents heart ailments
Most Useful Review
Cranberry effectively combats urinary tract infections and is significant in preventing cardiovascular disease, ageing, and cancer. It also promotes a balanced gut flora and strengthens my immune system against infections.
Vitamin Bs
8
Vitamin B6 may support heart health
Association of pyridoxal 5'-phosphate (PLP) with lipid profiles: a population-based cohort study.
Most Relevant Research
We aimed to understand how levels of Pyridoxal 5'-Phosphate (PLP), the active form of vitamin B6, relate to lipid profiles and potentially impact cardiovascular health. Using data from a large, population-based survey involving adults aged 20 and older, we conducted a thorough analysis of the relationships between PLP levels and cholesterol types, like LDL (bad) and HDL (good) cholesterol.
Our results showed that higher PLP levels were associated with lower levels of LDL cholesterol, suggesting that vitamin B6 might play a role in reducing the risk of cardiovascular issues. In fact, a single unit increase in PLP was linked to a significant decrease of around 17.7% in LDL cholesterol levels. Additionally, we found that PLP levels were positively correlated with HDL cholesterol levels, indicating that higher PLP could lead to an improvement in good cholesterol.
Notably, these associations seemed stronger in specific groups, such as diabetic individuals and those who abstain from alcohol. This points to a potential for vitamin B6 supplementation as a preventive measure against cardiovascular and metabolic diseases, particularly for those at higher risk. Overall, our findings illuminate vitamin B6 as a promising player in heart health discussions, particularly through its effects on cholesterol levels.
Our results showed that higher PLP levels were associated with lower levels of LDL cholesterol, suggesting that vitamin B6 might play a role in reducing the risk of cardiovascular issues. In fact, a single unit increase in PLP was linked to a significant decrease of around 17.7% in LDL cholesterol levels. Additionally, we found that PLP levels were positively correlated with HDL cholesterol levels, indicating that higher PLP could lead to an improvement in good cholesterol.
Notably, these associations seemed stronger in specific groups, such as diabetic individuals and those who abstain from alcohol. This points to a potential for vitamin B6 supplementation as a preventive measure against cardiovascular and metabolic diseases, particularly for those at higher risk. Overall, our findings illuminate vitamin B6 as a promising player in heart health discussions, particularly through its effects on cholesterol levels.
9.5
Improved health
Most Useful Review
I managed to lower my elevated homocysteine levels, associated with cardiovascular disease. It's vital to monitor this, as it can lead to serious conditions at a young age. This supplement has transformed my life, eliminating dizziness and weakness. Everyone should get tested annually for homocysteine levels. Best wishes for good health!
Spirulina
9.5
Boosts immunity
Most Useful Review
Spirulina has improved my skin and reduced my sweet cravings. Its impressive vitamin and mineral content is exceptional. As a supplement, it supports a range of health benefits, including cardiovascular disease prevention and immune system stimulation. I'm very pleased with the effects and recommend it for anyone looking to enhance their overall health.
9.5
Maintains heart health
Most Useful Review
Spirulina is an extraordinary remedy that improves overall health, boosts immunity, and regulates vital components for heart and skin health. As a vegan, I appreciate its vitamin B-12 content, crucial for maintaining health. It helps curb sweet cravings, promoting better choices and can benefit heart health, thus preventing cardiovascular disease.
Evening Primrose
8.8
Skin health improvement
Most Useful Review
This product is excellent with a fantastic price-to-quality ratio! I find it effective, especially in regulating hormonal production, notably oestrogen and progesterone, which alleviates irregular periods and eases menopause symptoms. Additionally, it improves skin condition, reduces cholesterol levels, and enhances my hair and nails' health. Evening primrose oil is genuinely beneficial for women’s health and beauty.
8.8
PMS relief noted
Most Useful Review
I greatly appreciate primrose oil; it has been transformative for my well-being. It alleviates PMS, improves my mood, and stops breast pain before menstruation. Just a reminder, as an Omega-6, it can promote inflammation, so I advise pairing it with Omega-3 for balance. Wishing everyone good health!
L Theanine
9
Inositol protects against cardiac damage
Oral supplementation of inositols effectively recovered lithium-induced cardiac dysfunctions in mice.
Most Relevant Research
We investigated how inositol supplementation could counteract heart issues caused by lithium in mice. Our study involved four groups of mice to explore the varying effects of inositol. One group received lithium alone, another received lithium followed by inositol, a third group had both lithium and inositol from the start, and a control group had no treatment at all.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
8.8
Support cardiovascular health
Most Useful Review
L-Theanine, an amino acid from green tea, promotes relaxation without drowsiness and supports the cardiovascular system. I've found it particularly effective when taken after a meal. Its effects are gradual, offering a soft sense of balance and clarity of thought without addiction or side effects. I've noticed no negative effects and consider it a noteworthy supplement that delivers on its promises.
Taurine
8
Taurine improves cholesterol metabolism
Taurine alleviates dysfunction of cholesterol metabolism under hyperuricemia by inhibiting A2AR-SREBP-2/CREB/HMGCR axis.
Most Relevant Research
We explored how taurine impacts cholesterol metabolism in individuals with hyperuricemia, a condition where uric acid levels are elevated and linked to higher cardiovascular disease risk. Our investigation revealed that taurine plays a significant role in regulating how the body processes cholesterol, particularly in the context of hyperuricemia.
In our research, we found that two purine metabolites—adenosine and inosine—are major players in cholesterol biosynthesis. These substances elevate the production of cholesterol by stimulating specific receptors in the body. However, we also discovered that a lack of taurine can worsen cholesterol metabolism issues in hyperuricemia.
When we administered taurine to mice with hyperuricemia, there was a notable reduction in cholesterol levels. This effect occurs largely because taurine inhibits the activity of adenosine A2A receptors, which are involved in cholesterol production. These findings suggest that boosting taurine levels may offer a promising strategy to combat both high cholesterol and hyperuricemia, potentially reducing cardiovascular risk in susceptible individuals.
Overall, our study provides valuable insights into how taurine might be utilized in therapies targeting cholesterol-related issues in patients suffering from hyperuricemia and associated cardiovascular challenges.
In our research, we found that two purine metabolites—adenosine and inosine—are major players in cholesterol biosynthesis. These substances elevate the production of cholesterol by stimulating specific receptors in the body. However, we also discovered that a lack of taurine can worsen cholesterol metabolism issues in hyperuricemia.
When we administered taurine to mice with hyperuricemia, there was a notable reduction in cholesterol levels. This effect occurs largely because taurine inhibits the activity of adenosine A2A receptors, which are involved in cholesterol production. These findings suggest that boosting taurine levels may offer a promising strategy to combat both high cholesterol and hyperuricemia, potentially reducing cardiovascular risk in susceptible individuals.
Overall, our study provides valuable insights into how taurine might be utilized in therapies targeting cholesterol-related issues in patients suffering from hyperuricemia and associated cardiovascular challenges.
9.5
Blood pressure reduction
Most Useful Review
I purchase taurine for my mother, who suffers from high blood pressure. It has helped her reduce the need for antihypertensive medication. She takes 0.5 tsp twice daily on an empty stomach. I'm pleased with the results; her health has improved, and I’m grateful for this supplement's positive impact on her cardiovascular disease.
Tumeric
8
Inhaled turmerone protects aorta
Inhaled turmerone can attenuate nicotine-induced degeneration of the aorta.
Most Relevant Research
We explored the effects of inhaled turmerone, a compound found in turmeric, on the degeneration of the aorta caused by nicotine. This research is significant because nicotine from secondhand smoke is known to increase the risk of cardiovascular disease. Our study focused on understanding how inhaled turmerone might counteract these harmful effects.
In our investigation, we observed that inhaling turmeric essential oil helped reduce the nicotine-induced damage, specifically protecting the elastic fibers in the aorta and decreasing levels of certain harmful enzymes. We noted that the blood of mice that inhaled the turmeric essential oil contained all three types of turmerone: α-turmerone, β-turmerone, and ar-turmerone. Among these, ar-turmerone emerged as the most effective in protecting the aorta from nicotine damage.
Overall, our findings suggest that inhaling turmerone may indeed help mitigate the negative impacts of nicotine on cardiovascular health, particularly regarding aortic degeneration. This opens up exciting possibilities for using turmeric and its components as a potential protective treatment against the risks associated with nicotine exposure.
In our investigation, we observed that inhaling turmeric essential oil helped reduce the nicotine-induced damage, specifically protecting the elastic fibers in the aorta and decreasing levels of certain harmful enzymes. We noted that the blood of mice that inhaled the turmeric essential oil contained all three types of turmerone: α-turmerone, β-turmerone, and ar-turmerone. Among these, ar-turmerone emerged as the most effective in protecting the aorta from nicotine damage.
Overall, our findings suggest that inhaling turmerone may indeed help mitigate the negative impacts of nicotine on cardiovascular health, particularly regarding aortic degeneration. This opens up exciting possibilities for using turmeric and its components as a potential protective treatment against the risks associated with nicotine exposure.
9.5
Strong antioxidant properties
Most Useful Review
I recommend this supplement wholeheartedly, regardless of existing health issues. It is an excellent antioxidant and high-quality product for combating inflammation. The benefits extend to fighting cancer as well. The packaging is commendable; this is suitable for adults of all ages.
Flax Seed Oil
8.3
Support for mother
Most Useful Review
I purchased this flax oil for my mother to maintain her cardiovascular health as she ages. It’s a natural option that helps her take care of herself.
8
Promotes cardiovascular function
Most Useful Review
This product supports heart health, cardiovascular disease, brain function, and joint lubrication.
Vitamin C
8
Antioxidants show promise for FGR
The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review.
Most Relevant Research
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
9.5
Effective varicose treatment
Most Useful Review
I was troubled by varicose veins, sinusitis, and periodontal disease. This vitamin C has effectively helped with my varicose veins, alongside propolis and Q10 for periodontal issues. Adding enzymes like Nattokinase and Serrapeptase has alleviated my sinusitis. I'm pleased with the results!
Red Yeast Rice
9
CoQ10 protects against heart injury
Coenzyme Q10 and its liposomal form prevent copper cardiotoxicity by attenuating oxidative stress, TLR-4/NF-κB signaling and necroptosis in rats.
Most Relevant Research
We explored the protective effects of Coenzyme Q10 (CoQ10) and its liposomal form on heart health, particularly in response to copper toxicity caused by copper sulfate (CuSO4). In this study, rats received daily doses of CuSO4 to induce heart injury, while some were also treated with CoQ10 or L-CoQ10 to see if these supplements could mitigate the damage.
The results showed that CuSO4 led to elevated cardiac injury markers and increased oxidative stress, which is known to contribute to heart issues. However, the inclusion of CoQ10 and L-CoQ10 helped lower the levels of harmful markers, improve antioxidant capacity, and reduce inflammation. These supplements effectively restored balance and reduced signs of heart injury, highlighting their potential cardioprotective roles.
Overall, the findings suggest that CoQ10 could serve as a valuable defense for individuals at risk of copper toxicity, reinforcing its relevance in supporting cardiovascular health.
The results showed that CuSO4 led to elevated cardiac injury markers and increased oxidative stress, which is known to contribute to heart issues. However, the inclusion of CoQ10 and L-CoQ10 helped lower the levels of harmful markers, improve antioxidant capacity, and reduce inflammation. These supplements effectively restored balance and reduced signs of heart injury, highlighting their potential cardioprotective roles.
Overall, the findings suggest that CoQ10 could serve as a valuable defense for individuals at risk of copper toxicity, reinforcing its relevance in supporting cardiovascular health.
8.8
No side effects
Most Useful Review
This supplement works well for cardiovascular disease. I take it on my doctor's recommendation to lower my cholesterol, as I don’t tolerate statins. There are no side effects, and my test results have improved slightly, so I will continue taking it.
Choline
9
Inositol protects against cardiac damage
Oral supplementation of inositols effectively recovered lithium-induced cardiac dysfunctions in mice.
Most Relevant Research
We investigated how inositol supplementation could counteract heart issues caused by lithium in mice. Our study involved four groups of mice to explore the varying effects of inositol. One group received lithium alone, another received lithium followed by inositol, a third group had both lithium and inositol from the start, and a control group had no treatment at all.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
9.5
Fatty liver control
Most Useful Review
I've used this product for 10 years after being diagnosed with fatty liver. Despite not changing my lifestyle, regular testing has shown normal liver function. Choline and inositol significantly help reduce fatty deposits, promoting liver health.
Cacao
9.5
Positive effects
Most Useful Review
The high quality of this cocoa is evident. It boasts excellent antioxidant properties that I believe protect my cardiovascular system. I find that it contributes to my overall health and leaves me feeling calm and rejuvenated.
9.5
Cognitive benefits
Most Useful Review
This cocoa is beneficial for brain health and has antioxidant properties that protect against inflammation. I’m convinced that regular intake improves blood flow to the brain, which could help in combating age-related cognitive declines, including Alzheimer's disease.
Zinc
7
Zinc's role in cardiovascular risk
Dietary zinc intake and 10-year atherosclerotic cardiovascular disease risk in diabetes mellitus patients: evidence from NHANES database.
Most Relevant Research
We explored the relationship between dietary zinc intake and the risk of atherosclerotic cardiovascular disease (ASCVD) in patients with diabetes mellitus (DM). Utilizing data from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2018, we calculated the 10-year ASCVD risk according to established clinical guidelines. Our analysis focused on dietary zinc intake based on food recall data from the participants.
The findings suggest that sufficient dietary zinc intake could positively influence cardiovascular health in diabetes patients. This is particularly important, as diabetes is closely linked with increased oxidative stress and inflammation, two factors that contribute to the development of heart disease. While we see an association between zinc and improved heart health, it's essential to note that further research is needed. Large-scale, well-designed prospective studies should aim to clarify the specific role of zinc in this context.
Overall, our results underscore the potential benefits of zinc for cardiovascular health, particularly in individuals managing diabetes. As we delve deeper into these associations, we aim to provide clearer guidance on how dietary choices can impact health outcomes for those living with diabetes.
The findings suggest that sufficient dietary zinc intake could positively influence cardiovascular health in diabetes patients. This is particularly important, as diabetes is closely linked with increased oxidative stress and inflammation, two factors that contribute to the development of heart disease. While we see an association between zinc and improved heart health, it's essential to note that further research is needed. Large-scale, well-designed prospective studies should aim to clarify the specific role of zinc in this context.
Overall, our results underscore the potential benefits of zinc for cardiovascular health, particularly in individuals managing diabetes. As we delve deeper into these associations, we aim to provide clearer guidance on how dietary choices can impact health outcomes for those living with diabetes.
9.5
Improved healing
Most Useful Review
Highly dosed and well-absorbed zinc is essential for proper immune function and brain development. A deficiency can lead to cognitive impairment and mental disorders. Zinc is also crucial for maintaining taste, vision, and testosterone production in men. My family used zinc monomethionine for deficiency; it aided my father's ulcer healing and improved my husband's vision and testosterone levels. Be cautious, though, as excessive zinc can interfere with copper absorption.
Folate
8
Folate lowers stroke risk
Association Between Serum Folate Concentrations and 10-Year Stroke Risk in a Prospective Community Cohort: Mediation and Interaction Analyses.
Most Relevant Research
We explored the connection between serum folate levels and stroke risk by examining a diverse group of 4,903 individuals from a Chinese community. Over a follow-up period of about 9.3 years, we recorded a total of 407 strokes, with the majority being ischemic strokes.
Our analysis revealed that individuals with higher folate levels (specifically those in the highest quartile, at 8.2 ng/mL or more) had a significantly lower risk of stroke. The data showed a hazard ratio of 0.68, indicating that these individuals were less likely to experience a stroke compared to those with lower folate levels.
An intriguing find was that homocysteine (Hcy) acted as a mediator in this relationship, accounting for about 14.5% of the connection between folate and stroke risk. Furthermore, we discovered that genetic factors, specifically the MTHFR gene polymorphism, could influence this relationship. We found that having the C677T genotype correlated with a positive impact of folate on stroke risk, while no such correlation was apparent for individuals with the other genotype.
Overall, the study suggests that adequate folate levels may be vital for reducing long-term stroke risk, with certain genetic variations playing a role in how folate affects cardiovascular health.
Our analysis revealed that individuals with higher folate levels (specifically those in the highest quartile, at 8.2 ng/mL or more) had a significantly lower risk of stroke. The data showed a hazard ratio of 0.68, indicating that these individuals were less likely to experience a stroke compared to those with lower folate levels.
An intriguing find was that homocysteine (Hcy) acted as a mediator in this relationship, accounting for about 14.5% of the connection between folate and stroke risk. Furthermore, we discovered that genetic factors, specifically the MTHFR gene polymorphism, could influence this relationship. We found that having the C677T genotype correlated with a positive impact of folate on stroke risk, while no such correlation was apparent for individuals with the other genotype.
Overall, the study suggests that adequate folate levels may be vital for reducing long-term stroke risk, with certain genetic variations playing a role in how folate affects cardiovascular health.
8
Reduced risk
Most Useful Review
Methylfolate is more easily absorbed than regular folic acid and acts quickly. It helps maintain normal homocysteine levels and reduces the risk of cardiovascular disease. It also addresses folic acid deficiency during pregnancy to prevent neural tube defects.
Magnesium
9
Magnesium may help arterial health
Mitigation of arteriosclerosis through transcriptional regulation of ferroptosis and lipid metabolism by magnesium.
Most Relevant Research
We investigated how magnesium impacts cardiovascular health, particularly its role in a condition known as arteriosclerosis. This disease can lead to serious heart complications, but recent studies revealed magnesium's potential benefits.
In a series of experiments involving human cells and animal models, we discovered that magnesium effectively reduces a process called ferroptosis, which is linked to the progression of arteriosclerosis. It appears that magnesium ions play a vital role by preventing certain proteins from breaking down. This action promotes the expression of protective proteins while reducing harmful components that contribute to the disease.
Notably, our animal tests highlighted that biodegradable magnesium stents not only hinder ferroptosis but also slow down the advancement of arteriosclerosis. This suggests that magnesium-based treatments could offer a promising avenue for combating cardiovascular diseases effectively.
In a series of experiments involving human cells and animal models, we discovered that magnesium effectively reduces a process called ferroptosis, which is linked to the progression of arteriosclerosis. It appears that magnesium ions play a vital role by preventing certain proteins from breaking down. This action promotes the expression of protective proteins while reducing harmful components that contribute to the disease.
Notably, our animal tests highlighted that biodegradable magnesium stents not only hinder ferroptosis but also slow down the advancement of arteriosclerosis. This suggests that magnesium-based treatments could offer a promising avenue for combating cardiovascular diseases effectively.
9.5
Essential for health
Most Useful Review
I recommend magnesium to all my patients as it is crucial for many bodily functions including those essential for cardiovascular disease. Deficiency can lead to several issues like fatigue and heartburn. It's best to use various forms for optimal benefits.
Astragalus Root
9.5
Supports heart health
Most Useful Review
Astragalus is remarkable for its medicinal properties, benefiting various conditions, including hypertension and cardiovascular disease. It aids in recovery, alleviates fatigue, and boosts immunity. I highly recommend it for overall health.
9.5
Heals tissues
Most Useful Review
The properties of Astragalus are remarkable. Clinical studies show it aids in healing and recovering tissues, suggesting it also supports cardiovascular health, making it a beneficial herb in my regimen for stress management.
Docosahexaenoic Acid
8
Omega-3 lowers coronary risks
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We explored the impact of omega-3 fatty acid supplementation, particularly docosahexaenoic acid (DHA), on cardiovascular health through the Vitamin D and Omega-3 Trial (VITAL). This comprehensive study included nearly 26,000 older adults from the U.S., who received a daily dose of 840 mg of omega-3 fatty acids.
Although we anticipated significant benefits, the results showed no overall reductions in major cardiovascular events, such as heart attacks and strokes, among the participants. However, our Bayesian analyses, which considered earlier research, suggested that omega-3 FA may still lower the risk of coronary events specifically.
While the evidence pointed towards limited effectiveness for stroke prevention, there seems to be a stronger case for incorporating omega-3 supplementation for reducing coronary-related issues. Overall, these findings enhance our understanding of how consistent omega-3 intake can be a valuable tool in primary prevention strategies for heart health.
Although we anticipated significant benefits, the results showed no overall reductions in major cardiovascular events, such as heart attacks and strokes, among the participants. However, our Bayesian analyses, which considered earlier research, suggested that omega-3 FA may still lower the risk of coronary events specifically.
While the evidence pointed towards limited effectiveness for stroke prevention, there seems to be a stronger case for incorporating omega-3 supplementation for reducing coronary-related issues. Overall, these findings enhance our understanding of how consistent omega-3 intake can be a valuable tool in primary prevention strategies for heart health.
9.5
Metabolism improvement
Most Useful Review
I have not eaten meat, fish, or seafood since 2008, so Omega-3 and vitamin B-12 are vital for me. Omega-3 improves metabolism, dilutes blood to prevent clots, and supports cardiovascular health. It also inhibits skin ageing, enhances joint function, and positively impacts brain function and mood. Without enough Omega-3, one might face issues such as dry skin, fatigue, frequent colds, and depression. To avoid these symptoms, it's essential to consume Omega-3 rich foods or take supplements like this product.
Vitamin B12
8
Vitamin B12 reduces cardiovascular risks
Association of MTHFR C677T, MTHFRA1298C, and MTRRA66G Gene Polymorphisms with Hyperhomocysteinemia and Its Modulation by the Combined Effect of Vitamin B12 and Folate in Chinese Population with Hypertension.
Most Relevant Research
We explored the connection between vitamin B12, genetic factors, and cardiovascular health in a group of Chinese adults suffering from hypertension. By analyzing the genetic variations of individuals, we aimed to understand how these may influence levels of homocysteine, an amino acid that can impact heart health when present in high amounts.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
Our study included 1,304 participants over the age of 18. We measured their serum levels of vitamin B12 and folate, as well as their total homocysteine concentrations. The findings were quite significant: adequate levels of both vitamin B12 and folate were linked to lower homocysteine levels. This suggests that ensuring proper nutrition might be key to managing cardiovascular risks associated with high homocysteine.
We also noticed that the genotypic effects on homocysteine levels could be lessened with sufficient intake of these vitamins. Targeted nutritional interventions, such as increasing vitamin B12 and folate in the diet, could therefore play an essential role in heart health for those at risk. Our results emphasize the importance of nutrition in supporting cardiovascular health and managing hypertension.
9.5
Improved red blood cells
Most Useful Review
This form of B12 genuinely works, as our lab results confirmed. While dealing with pernicious anaemia linked to blood cancer, I found traditional B12 ineffective. Once we began using this activated version, we observed a halt in the decline of hemoglobin levels, eventually seeing improvement. Regular use kept my red blood cell count above 8.5. It's vital for the formation of red blood cells, and many doctors underestimate its importance, despite the need for sufficient iron.
Omega 3
8
Eicosapentaenoic acid reduces coronary risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We explored how eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, influences cardiovascular health by analyzing the Vitamin D and Omega-3 Trial (VITAL). This large, randomized controlled trial involved 25,871 older adults in the U.S., with a median follow-up of 5.3 years to assess the effects of daily supplementation.
Initially, the results seemed non-significant for major cardiovascular events. However, our Bayesian analysis, which incorporated previous research, showed more positive outcomes. We observed that EPA supplementation could significantly reduce the risk of coronary events, such as total coronary heart disease (CHD) and myocardial infarction, while it didn’t seem to impact stroke rates.
These findings enhance our understanding of omega-3 supplements in preventing heart-related issues, emphasizing their potential as a primary preventative measure against coronary diseases.
Initially, the results seemed non-significant for major cardiovascular events. However, our Bayesian analysis, which incorporated previous research, showed more positive outcomes. We observed that EPA supplementation could significantly reduce the risk of coronary events, such as total coronary heart disease (CHD) and myocardial infarction, while it didn’t seem to impact stroke rates.
These findings enhance our understanding of omega-3 supplements in preventing heart-related issues, emphasizing their potential as a primary preventative measure against coronary diseases.
9.5
Cholesterol regulation
Most Useful Review
This dietary supplement, made from anchovy and sardines, has easy-to-swallow capsules with a pleasant strawberry flavour. It helps normalise cholesterol levels and reduces the risk of cardiovascular disease. Taking two capsules after meals improves hair and nail health. Focus on nutrition and health!
Eicosapentaenoic Acid
8
Eicosapentaenoic acid reduces coronary risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We explored how eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, influences cardiovascular health by analyzing the Vitamin D and Omega-3 Trial (VITAL). This large, randomized controlled trial involved 25,871 older adults in the U.S., with a median follow-up of 5.3 years to assess the effects of daily supplementation.
Initially, the results seemed non-significant for major cardiovascular events. However, our Bayesian analysis, which incorporated previous research, showed more positive outcomes. We observed that EPA supplementation could significantly reduce the risk of coronary events, such as total coronary heart disease (CHD) and myocardial infarction, while it didn’t seem to impact stroke rates.
These findings enhance our understanding of omega-3 supplements in preventing heart-related issues, emphasizing their potential as a primary preventative measure against coronary diseases.
Initially, the results seemed non-significant for major cardiovascular events. However, our Bayesian analysis, which incorporated previous research, showed more positive outcomes. We observed that EPA supplementation could significantly reduce the risk of coronary events, such as total coronary heart disease (CHD) and myocardial infarction, while it didn’t seem to impact stroke rates.
These findings enhance our understanding of omega-3 supplements in preventing heart-related issues, emphasizing their potential as a primary preventative measure against coronary diseases.
9.5
Improves cardiovascular health
Most Useful Review
Wonderful! A great fish oil. Omega 3 can lower the risk of cardiovascular disease and improve blood circulation. It enhances cognitive functions and memory, reduces blood pressure, and aids in diabetes prevention. My family takes omega regularly and finds it offers an ideal price-quality ratio. The capsules are large but easy to swallow.
Fish Oil
8
Eicosapentaenoic acid reduces coronary risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We explored how eicosapentaenoic acid (EPA), a key component of omega-3 fatty acids, influences cardiovascular health by analyzing the Vitamin D and Omega-3 Trial (VITAL). This large, randomized controlled trial involved 25,871 older adults in the U.S., with a median follow-up of 5.3 years to assess the effects of daily supplementation.
Initially, the results seemed non-significant for major cardiovascular events. However, our Bayesian analysis, which incorporated previous research, showed more positive outcomes. We observed that EPA supplementation could significantly reduce the risk of coronary events, such as total coronary heart disease (CHD) and myocardial infarction, while it didn’t seem to impact stroke rates.
These findings enhance our understanding of omega-3 supplements in preventing heart-related issues, emphasizing their potential as a primary preventative measure against coronary diseases.
Initially, the results seemed non-significant for major cardiovascular events. However, our Bayesian analysis, which incorporated previous research, showed more positive outcomes. We observed that EPA supplementation could significantly reduce the risk of coronary events, such as total coronary heart disease (CHD) and myocardial infarction, while it didn’t seem to impact stroke rates.
These findings enhance our understanding of omega-3 supplements in preventing heart-related issues, emphasizing their potential as a primary preventative measure against coronary diseases.
8.8
Supports cardiovascular health
Most Useful Review
Strengthening the cardiovascular system, Omegas from this company have been incredibly effective for me! Each product has its merits, and this one stands out for support in the cardiovascular system due to its high EPA content. For brain activity enhancement, opt for Omega with higher DHA, although this also has a substantial DHA level. Please like if you found my review helpful!
Vitamin D3
7
Vitamin D3's influence on CVD risk
Perirenal fat differs in patients with chronic kidney disease receiving different vitamin D-based treatments: a preliminary study.
Most Relevant Research
We explored how different vitamin D treatments may influence cardiovascular disease (CVD) risk among patients with chronic kidney disease (CKD). Our observational study included 83 CKD patients who were treated with vitamin D or its analogs and had varying histories of CVD. By measuring the thickness of perirenal adipose tissue (PAT) and assessing clinical parameters, we aimed to uncover any links between vitamin D treatment and cardiovascular health.
We found that patients with a history of CVD showed thicker PAT compared to those without such a history. Interestingly, our comparisons among patients receiving different forms of vitamin D revealed that those treated with paricalcitol had less PAT accumulation than those on cholecalciferol or calcitriol. This suggests that the type of vitamin D treatment may play a role in managing CVD risk in CKD patients.
Although our findings indicate differences in PAT thickness related to vitamin D treatment, we did not conduct a controlled trial that would allow us to claim a definitive benefit of vitamin D3 alone on cardiovascular health. It appears that further investigation is necessary to clarify these relationships and understand the mechanisms at play.
We found that patients with a history of CVD showed thicker PAT compared to those without such a history. Interestingly, our comparisons among patients receiving different forms of vitamin D revealed that those treated with paricalcitol had less PAT accumulation than those on cholecalciferol or calcitriol. This suggests that the type of vitamin D treatment may play a role in managing CVD risk in CKD patients.
Although our findings indicate differences in PAT thickness related to vitamin D treatment, we did not conduct a controlled trial that would allow us to claim a definitive benefit of vitamin D3 alone on cardiovascular health. It appears that further investigation is necessary to clarify these relationships and understand the mechanisms at play.
9.5
Immunity boost
Most Useful Review
I take one capsule of vitamin D3 daily. It reliably supports my body’s immunity against various viral diseases. Over the years of regular intake, my family, including children, has not experienced any significant illness, only mild colds. As someone with thyroid disease, this supplement is essential for me as vitamin D deficiency is linked to autoimmune conditions such as Hashimoto's and even type 1 diabetes, enhancing my resistance to cardiovascular disease.
Vitamin D
5
Vitamin D's role in exercise capacity
Vitamin D levels correlate with exercise capacity in adults with CHD.
Most Relevant Research
We investigated how vitamin D influences exercise capability in adults with congenital heart disease (CHD). In our study, we looked at 55 CHD patients and compared them to 55 healthy individuals of similar age and gender. We measured the vitamin D levels in participants and assessed their exercise performance, heart function, and muscle strength.
Surprisingly, we found that while 93% of CHD patients and 91% of the control group had low vitamin D levels, there was no significant difference between the two groups. Additionally, although we did not see a connection between vitamin D levels and factors like age, weight, or muscle strength, we did notice that higher vitamin D levels were related to better exercise capacity in those with CHD.
This suggests that vitamin D insufficiency is common among those with congenital heart defects and can hinder their ability to exercise. Importantly, we recommend more research to explore if vitamin D supplementation, alongside exercise programs, might benefit individuals with low vitamin D levels and improve their overall physical performance.
Surprisingly, we found that while 93% of CHD patients and 91% of the control group had low vitamin D levels, there was no significant difference between the two groups. Additionally, although we did not see a connection between vitamin D levels and factors like age, weight, or muscle strength, we did notice that higher vitamin D levels were related to better exercise capacity in those with CHD.
This suggests that vitamin D insufficiency is common among those with congenital heart defects and can hinder their ability to exercise. Importantly, we recommend more research to explore if vitamin D supplementation, alongside exercise programs, might benefit individuals with low vitamin D levels and improve their overall physical performance.
9.5
Effective treatment
Most Useful Review
I drank this for six months, and my vitamin D levels rose significantly. This form is particularly effective for those with autoimmune diseases and related issues. It is convenient to take, with a pleasant taste.
Probiotics
7
Potential of selenium and zinc postbiotics
Gut Microbiota Modulation by Selenium and Zinc Enrichment Postbiotic on Dysbiosis Associated with Hypertension.
Most Relevant Research
We explored the role of selenium and zinc enriched postbiotic yeast in addressing gut dysbiosis linked to cardiovascular disease. This study involved analyzing the effects of these postbiotics on microbial populations in the digestive system using various scientific methods.
We found that treatment with the enriched postbiotics led to a notable increase in beneficial bacteria and acetic acid levels. These results suggest that selenium and zinc postbiotics may hold therapeutic potential as adjuncts in treating cardiovascular diseases by improving gut health.
We found that treatment with the enriched postbiotics led to a notable increase in beneficial bacteria and acetic acid levels. These results suggest that selenium and zinc postbiotics may hold therapeutic potential as adjuncts in treating cardiovascular diseases by improving gut health.
9.5
Remission for Crohn's
Most Useful Review
I really like this probiotic and would give it ten stars if possible. My husband has severe Crohn's Disease, and his doctor said hospice was the next step. This product has put his disease into remission, and he is significantly better with this formula. It's truly amazing!
Calcium
7
Calcium's limited impact on hypertension
Calcium, magnesium, and vitamin D supplementations as complementary therapy for hypertensive patients: a systematic review and meta-analysis.
Most Relevant Research
We sought to understand how calcium affects hypertension and cardiovascular disease risk. Through a thorough review of existing literature, we evaluated data from a significant number of studies, focusing on the effects of calcium, magnesium, and vitamin D supplements on blood pressure levels and pulse rates.
Our analysis revealed that while calcium supplementation was linked to a noteworthy drop in diastolic blood pressure (the bottom number in blood pressure readings), it did not show a significant impact on systolic blood pressure (the top number) or pulse rate. This indicates that calcium could play a role in managing the lower blood pressure readings but may not be entirely effective on its own regarding overall blood pressure control.
Additionally, we identified that magnesium also contributed positively by reducing diastolic blood pressure, whereas vitamin D exhibited a broader beneficial effect by lowering both systolic and diastolic blood pressure. Despite these encouraging results for magnesium and vitamin D, calcium’s isolated effectiveness in addressing hypertension remains limited.
Overall, while calcium may help with certain aspects of blood pressure management, its role in controlling hypertension is not as clear-cut as we might hope.
Our analysis revealed that while calcium supplementation was linked to a noteworthy drop in diastolic blood pressure (the bottom number in blood pressure readings), it did not show a significant impact on systolic blood pressure (the top number) or pulse rate. This indicates that calcium could play a role in managing the lower blood pressure readings but may not be entirely effective on its own regarding overall blood pressure control.
Additionally, we identified that magnesium also contributed positively by reducing diastolic blood pressure, whereas vitamin D exhibited a broader beneficial effect by lowering both systolic and diastolic blood pressure. Despite these encouraging results for magnesium and vitamin D, calcium’s isolated effectiveness in addressing hypertension remains limited.
Overall, while calcium may help with certain aspects of blood pressure management, its role in controlling hypertension is not as clear-cut as we might hope.
8.8
Improved bone strength
Most Useful Review
Wonderful! Everyone knows about the benefits of calcium for teeth and bones, yet many still experience insufficient bone strength. This often occurs because calcium is not taken with magnesium. I took these vitamins during pregnancy, and they helped with cramps and maintaining healthy nails and hair. If my review is useful, please support me. I drink these vitamins regularly and recommend them to all.
Iron
7
Iron deficiency impacts heart failure
Impact of iron deficiency on congestion and postdischarge survival in patients recently hospitalised for decompensated heart failure: a multicentre, prospective, observational analysis of the FERIC-RO study.
Most Relevant Research
Our investigation focused on the impact of iron deficiency in patients with worsening chronic heart failure, seeking clarity on how it affects their condition and recovery. We enrolled 163 patients from multiple centers who were hospitalized for this serious health issue. By evaluating iron deficiency at discharge, we distinguished those affected by low iron levels and compared various health indicators between groups.
We discovered that over half of the patients, 54.6%, had iron deficiency. Those with lower iron were more likely to exhibit signs of congestion and were categorized into more advanced heart failure classes. Interestingly, their levels of NT-proBNP, a crucial marker associated with heart failure, were significantly higher upon admission and didn’t improve much during their hospital stay.
While we found that mortality rates within 30 days had no significant difference between patients with and without iron deficiency, a notable increase in deaths was observed at 90 days post-discharge for those with iron deficiency. This suggests that iron levels could potentially influence recovery, especially in the longer term.
In conclusion, patients dealing with both chronic heart failure and iron deficiency showed more unresolved symptoms and poorer outcomes post-discharge. These findings highlight the importance of monitoring iron levels in patients facing heart issues, paving the way for future studies into treatment effectiveness and potential benefits of iron therapies.
We discovered that over half of the patients, 54.6%, had iron deficiency. Those with lower iron were more likely to exhibit signs of congestion and were categorized into more advanced heart failure classes. Interestingly, their levels of NT-proBNP, a crucial marker associated with heart failure, were significantly higher upon admission and didn’t improve much during their hospital stay.
While we found that mortality rates within 30 days had no significant difference between patients with and without iron deficiency, a notable increase in deaths was observed at 90 days post-discharge for those with iron deficiency. This suggests that iron levels could potentially influence recovery, especially in the longer term.
In conclusion, patients dealing with both chronic heart failure and iron deficiency showed more unresolved symptoms and poorer outcomes post-discharge. These findings highlight the importance of monitoring iron levels in patients facing heart issues, paving the way for future studies into treatment effectiveness and potential benefits of iron therapies.
9.5
Gentle iron absorption
Most Useful Review
A friend's iron level fell significantly, but after three months of using this supplement, it improved from 85 to 125. We started with two capsules daily, then reduced the dose gradually. However, always investigate the reason behind low iron levels before treatment, as sometimes the body lowers iron intentionally due to health issues.