NAC protects lungs from damageN‑acetyl‑L‑cysteine protects rat lungs and RLE‑6TN cells from cigarette smoke‑induced oxidative stress. We examined how N-acetyl-L-cysteine (NAC) impacts lung health in the context of chronic obstructive pulmonary disease (COPD) by exposing rats to cigarette smoke (CS) over a four-week period. This study set up a model of lung injury to assess the damage caused by CS and the protective effects of NAC.
After exposure, we observed significant changes in the lung tissue, including widening of the alveolar walls and increased inflammatory cell infiltration, suggesting serious oxidative injury. We found that NAC treatment helped counteract some of the harmful effects, reducing markers of oxidative stress like malondialdehyde while boosting protective enzymes such as superoxide dismutase.
Additionally, we noted that in lung cells exposed to cigarette smoke, NAC also mitigated apoptosis, which is a form of programmed cell death induced by oxidative stress. This underscores the potential for NAC as a therapeutic agent to replenish the body’s glutathione and aid in protecting lung health amidst the damaging effects of smoking.
Overall, our findings point to NAC's beneficial role in shielding lung tissues from damage due to cigarette smoke, reinforcing its use as an antioxidant in managing COPD. Avoids Exacerbations Most Useful Review 1 people found this helpful I have been using this NAC for several years and remain satisfied. It is a cost-effective analogue to pharmaceutical preparations containing the same active ingredient. NAC proves useful for chronic obstructive pulmonary disease, acting on the bronchial tube lining. I take it during winter at a dosage of 1000-1200 mg daily to prevent severe exacerbations of the disease, especially in an elderly relative with Parkinson's disease. |
Asthma control improved Most Useful Review 14 people found this helpful BroccoMax has the most affordable delivery charge I've encountered when ordering online, and I truly appreciate the timely delivery. This product is fantastic; I ordered it after learning about its benefits regarding Chronic Obstructive Pulmonary Disease (COPD). I have had asthma for 40 years, and alongside another herbal product that helps me manage my condition, BroccoMax significantly alleviates the residual damage caused by years of inflammation and steroid inhaler use. For the first time in 40 years, I have discarded all my inhalers, showing my confidence in the products I'm currently using to control my asthma. Thank you for the excellent service; I wholeheartedly recommend your company! Positive effects noted Most Useful Review 8 people found this helpful A godsend for airways! I’ve experienced a powerful, positive effect on my Chronic Obstructive Pulmonary Disease (COPD) and smoking-related airway diseases in general. |
NAC's versatility Most Useful Review 5 people found this helpful NAC works wonderfully! In my profession, I prescribe it for patients with various conditions, serving as an expectorant and anti-inflammatory agent. It's effective in treating chronic obstructive pulmonary disease and other issues, enhancing glutathione production. I recommend it as part of a comprehensive treatment plan, although individual intolerances should always be considered. Profitable alternative Most Useful Review I have been using NAC for several years now with satisfaction. It's a cost-effective alternative to pharmaceutical drugs with the same active ingredient. NAC is helpful for chronic obstructive pulmonary disease, benefiting the bronchi lining. Taking it daily during winter at 1000-1200 mg helps prevent severe exacerbations. The capsules are easy to swallow. |