Vitamins
8
Vitamin D3 aids gastritis relief
[Vitamin D3 alleviates the gastritis that associated with Helicobacter pylori infection in mice with hypercholesterolemia by enhancing the activity of vitamin D receptors in the liver tissue and blocking the signaling pathway of JAK/STAT3].
Most Relevant Research
This study focused on how vitamin D3 (VD3) might help alleviate gastritis, particularly in the context of Helicobacter pylori (Hp) infection and high cholesterol levels. We established mouse models that reflected these conditions and then treated them with VD3 for eight weeks. After treatment, we observed significant positive changes in the liver and stomach tissues of the mice.
Notably, we found that the levels of vitamin D receptors (VDR) and a related protein called Insig-2 increased in the liver of the mice that had high cholesterol and were also infected with Hp. This indicates that VD3 enhances the activity of these important receptors, which might contribute to its gastroprotective effects. Additionally, we saw a reduction in serum gastrin levels, which can be important in regulating stomach function.
We also noted decreased expression of JAK and STAT3 proteins, which are part of a cellular signaling pathway known to be involved in inflammation. Delving deeper, the treatment with VD3 led to lower levels of COX2—a protein associated with inflammation—in the gastric tissue. Furthermore, serum cholesterol levels decreased, and we observed a reduction in inflammatory markers like IL-8.
Ultimately, our findings suggest that VD3 may offer a beneficial approach to managing gastritis by modulating inflammation and improving liver function, especially in those with high cholesterol and Hp infection. We can cautiously conclude that VD3 has promising potential in this area, although further research could solidify these findings.
Notably, we found that the levels of vitamin D receptors (VDR) and a related protein called Insig-2 increased in the liver of the mice that had high cholesterol and were also infected with Hp. This indicates that VD3 enhances the activity of these important receptors, which might contribute to its gastroprotective effects. Additionally, we saw a reduction in serum gastrin levels, which can be important in regulating stomach function.
We also noted decreased expression of JAK and STAT3 proteins, which are part of a cellular signaling pathway known to be involved in inflammation. Delving deeper, the treatment with VD3 led to lower levels of COX2—a protein associated with inflammation—in the gastric tissue. Furthermore, serum cholesterol levels decreased, and we observed a reduction in inflammatory markers like IL-8.
Ultimately, our findings suggest that VD3 may offer a beneficial approach to managing gastritis by modulating inflammation and improving liver function, especially in those with high cholesterol and Hp infection. We can cautiously conclude that VD3 has promising potential in this area, although further research could solidify these findings.
9.5
Gentle on stomach
Most Useful Review
I chose this non-acidic form of vitamin C as it doesn’t irritate my stomach lining, making it perfect for anyone with gastritis. It’s suitable for healthy individuals too. The addition of citrus bioflavonoids aids absorption. I highly recommend it!
Tumeric
8
Curcumin protects against deltamethrin
Residual Level Of Deltamethrin Induced Gastritis And Preventive Role Of Curcumin On Stomach Mucosa.
Most Relevant Research
In this study, we explored the impact of curcumin on gastritis induced by deltamethrin, a pesticide that could harm our stomach lining. Deltamethrin, even at levels deemed safe by the WHO, was found to have toxic effects when given to rats. The research involved two treatment groups along with a control group to help measure the outcomes more accurately.
We administered deltamethrin to one group of rats while providing them with curcumin to see if it would protect their stomach linings. This setup allowed us to evaluate not just the damaging effects of deltamethrin but also the potential of curcumin as a protective aid.
Our findings confirmed that deltamethrin can indeed be harmful to the stomach, but we also observed that curcumin demonstrated a protective role against the toxic effects. Thus, while deltamethrin poses risks when consumed in residues from treated crops, curcumin offers a promising way to safeguard our gastric health.
We administered deltamethrin to one group of rats while providing them with curcumin to see if it would protect their stomach linings. This setup allowed us to evaluate not just the damaging effects of deltamethrin but also the potential of curcumin as a protective aid.
Our findings confirmed that deltamethrin can indeed be harmful to the stomach, but we also observed that curcumin demonstrated a protective role against the toxic effects. Thus, while deltamethrin poses risks when consumed in residues from treated crops, curcumin offers a promising way to safeguard our gastric health.
9.5
Helpful for gastritis
Most Useful Review
This curcumin is free from pepper, making it suitable for my gastritis. It does not upset my stomach and has significantly helped with body replenishment, allergies, and pain in my spine and joints. While taking it, I experienced no discomfort. I consumed two cans, taking one capsule a day. I plan to repeat the course soon.
9.5
Gastritis control tablets
Most Useful Review
These tablets are miraculous for various stomach issues. I frequently experience gastritis and upset stomach, yet they consistently help, particularly with nausea.
8.8
Effective gastritis relief
Most Useful Review
I have chronic gastritis, and the Pepto syrup certainly alleviated my attacks, which were truly dreadful and bitter but effective. It is now available in capsules, which are much better.
Zinc
8
Zinc protects against gastritis damage
Zinc supplementation alleviates oxidative stress to inhibit chronic gastritis the ROS/NF-κB pathway in a mouse model.
Most Relevant Research
We investigated how zinc supplementation impacts chronic gastritis, particularly in the context of oxidative stress and inflammation. By establishing models of inflammatory injury in C57BL/6 mice, we were able to analyze the effects of zinc on the gastric mucosa, which is crucial for maintaining digestive health.
Our findings revealed that when the mice were exposed to a compound known to induce inflammation, there was a noticeable rise in reactive oxygen species (ROS), signaling an increase in oxidative stress. This stress resulted in an uptick in certain harmful factors related to inflammation and cell death. However, when we introduced zinc as a supplement, it effectively reduced these damaging factors, alleviating inflammation and the resulting cell death in both the mouse stomach and cultured cells.
Overall, our study indicates that zinc supplementation can play a significant role in controlling inflammation and protecting against cellular damage caused by oxidative stress in chronic gastritis. By modulating the ROS/NF-κB signaling pathway, zinc demonstrates potential as a protective agent for gastric health.
Our findings revealed that when the mice were exposed to a compound known to induce inflammation, there was a noticeable rise in reactive oxygen species (ROS), signaling an increase in oxidative stress. This stress resulted in an uptick in certain harmful factors related to inflammation and cell death. However, when we introduced zinc as a supplement, it effectively reduced these damaging factors, alleviating inflammation and the resulting cell death in both the mouse stomach and cultured cells.
Overall, our study indicates that zinc supplementation can play a significant role in controlling inflammation and protecting against cellular damage caused by oxidative stress in chronic gastritis. By modulating the ROS/NF-κB signaling pathway, zinc demonstrates potential as a protective agent for gastric health.
8.3
Comfortable zinc intake
Most Useful Review
I suffer from atrophic gastritis and functional dyspepsia. I struggled with stomachaches from zinc, but this bisglycinate chelated zinc was recommended for those with sensitive stomachs. Now, I can take it comfortably, and I haven’t experienced the white spots on my nails since starting. If you have stomach discomfort with zinc, try zinc bisglycinate.
Probiotics
8
Probiotic impact on gastritis tested
Alleviation of Helicobacter pylori- or aspirin-induced gastritis and neuroinflammation in mice by Lactococcus lactis and Bifidobacterium longum.
Most Relevant Research
We explored the effectiveness of the probiotics Lactococcus lactis P135 and Bifidobacterium longum P142 in combating gastritis linked to Helicobacter pylori (HP) in mice. Our findings indicated that these probiotics significantly reduced HP growth and the resulting inflammation. When administered orally, they were able to alleviate symptoms of HP- and aspirin-induced gastritis while also improving cognitive behavior.
Despite the promising results, it’s important to note that the effects were observed in mice, and further research is needed to confirm if these benefits translate to humans.
Despite the promising results, it’s important to note that the effects were observed in mice, and further research is needed to confirm if these benefits translate to humans.
8.8
Effective for IBS
Most Useful Review
I recommend these probiotics. I struggled with flatulence and gastritis for two months. After taking these probiotics three times daily, I felt a slight improvement in a couple of weeks and was quite pleased after a month, as my flatulence nearly disappeared and my gut function improved. I also gave my five-year-old two doses daily after antibiotics, and their bowel movements became regular within days. The capsules are intact after dissolving in warm milk, which indicates live bacteria.
Vitamin C
9
Vitamin C improves chronic gastritis
Vitamin C Mediates IGFBP7 to Alleviate Chronic Atrophic Gastritis via the HIF-1α/VEGF Pathway.
Most Relevant Research
We investigated how vitamin C might help improve chronic atrophic gastritis (CAG), a condition characterized by gastric mucosal damage and inflammation. Our research utilized data from a well-known dataset, focusing on changes in gene expression related to CAG. Notably, we pinpointed IGFBP7 as a central gene that appeared to be strongly associated with this condition.
In our study, we treated CAG patients with vitamin C and observed significant improvements in blood parameters and the overall health of their gastric mucosa. Moreover, when we looked at gastric cells in the lab, vitamin C not only boosted cell viability but also reduced inflammation and cell death caused by a harmful compound known as MNNG. These effects included lowering the levels of inflammatory markers and apoptosis-related proteins.
Interestingly, our findings suggested that IGFBP7 plays a role in these protective effects of vitamin C. When we knocked down IGFBP7 in the lab tests, we noted changes in how vitamin C worked, suggesting a complex interaction.
Overall, our study highlights the potential of vitamin C and IGFBP7 as key players in managing chronic atrophic gastritis and enhancing gastric health, opening doors for new therapeutic approaches.
In our study, we treated CAG patients with vitamin C and observed significant improvements in blood parameters and the overall health of their gastric mucosa. Moreover, when we looked at gastric cells in the lab, vitamin C not only boosted cell viability but also reduced inflammation and cell death caused by a harmful compound known as MNNG. These effects included lowering the levels of inflammatory markers and apoptosis-related proteins.
Interestingly, our findings suggested that IGFBP7 plays a role in these protective effects of vitamin C. When we knocked down IGFBP7 in the lab tests, we noted changes in how vitamin C worked, suggesting a complex interaction.
Overall, our study highlights the potential of vitamin C and IGFBP7 as key players in managing chronic atrophic gastritis and enhancing gastric health, opening doors for new therapeutic approaches.
9.5
Gentle on stomach
Most Useful Review
This vitamin C is my go-to remedy. It's high quality with 500 mg of vitamin C and bioflavonoids, making for an excellent combination. The non-acidic form is gentle on the stomach, suitable for gastritis sufferers. I take 2 capsules daily when ill, and it works wonders for my immune system.
Coenzyme Q10
8
CoQ10 improves gastritis treatment
Coenzyme Q10 in combination with triple therapy regimens ameliorates oxidative stress and lipid peroxidation in chronic gastritis associated with H. pylori infection.
Most Relevant Research
We investigated the potential benefits of coenzyme Q10 (CoQ10) in treating chronic gastritis linked to H. pylori infection. In our clinical trial, we randomly divided 100 participants into two groups: one received a standard triple therapy regimen, while the other received the same treatment with the addition of CoQ10.
Our findings were promising. We observed a significant decrease in inflammation scores among those who took CoQ10 alongside the triple therapy compared to those who only received the base treatment. Additionally, we noted that the antioxidant levels in the CoQ10 group improved notably over the duration of the study. Specifically, the total antioxidant capacity and glutathione peroxidase levels were significantly better in the intervention group than at the start of the study.
Combining CoQ10 with standard treatment appeared to effectively address both mucosal inflammation and oxidative stress in patients suffering from chronic gastritis. This suggests a compelling advantage to including CoQ10 in treatment regimens for such conditions.
Our findings were promising. We observed a significant decrease in inflammation scores among those who took CoQ10 alongside the triple therapy compared to those who only received the base treatment. Additionally, we noted that the antioxidant levels in the CoQ10 group improved notably over the duration of the study. Specifically, the total antioxidant capacity and glutathione peroxidase levels were significantly better in the intervention group than at the start of the study.
Combining CoQ10 with standard treatment appeared to effectively address both mucosal inflammation and oxidative stress in patients suffering from chronic gastritis. This suggests a compelling advantage to including CoQ10 in treatment regimens for such conditions.
8
Metabolic improvement
Most Useful Review
Coenzyme has significantly improved my metabolic processes and reduced my cravings for high-calorie foods, making it beneficial for weight loss. Additionally, I advise against taking it if you have gastritis or any erosive gastrointestinal issues, as it should not be consumed on an empty stomach or at night. Overall, I highly recommend this remarkable supplement.
Iron
8
Impact of Iron on Gastritis
Collagenous and lymphocytic gastritis in pediatric patients. A single-center experience observing an increase in diagnosis in recent years.
Most Relevant Research
We explored the effects of iron treatment on children diagnosed with collagenous gastritis (CG) and lymphocytic gastritis (LG). Over a period from 2000 to 2023, we reviewed cases that revealed a notable increase in diagnoses, highlighting the importance of awareness among healthcare providers.
Out of 31 children observed, iron deficiency anemia was present in 22 of them. The study showed that iron supplementation was commonly used, with 77% of the children receiving it. Notably, we found that after treatment, hemoglobin levels normalized in most cases, indicating that iron may indeed play a significant role in managing anemia associated with these types of gastritis.
However, it's crucial to mention that 29% of the patients required additional iron supplementation even after their levels normalized. This suggests that while iron treatment can benefit those suffering from anemia due to gastritis, it may not completely resolve the underlying issues for everyone. We also noted that repeat endoscopies did not reveal any significant changes in gastric histopathology, which indicates that while the symptoms could improve with treatment, the condition itself might not necessarily change.
Ultimately, our findings encourage healthcare professionals to consider CG and LG more seriously in pediatric patients, especially when treating related conditions like iron deficiency anemia.
Out of 31 children observed, iron deficiency anemia was present in 22 of them. The study showed that iron supplementation was commonly used, with 77% of the children receiving it. Notably, we found that after treatment, hemoglobin levels normalized in most cases, indicating that iron may indeed play a significant role in managing anemia associated with these types of gastritis.
However, it's crucial to mention that 29% of the patients required additional iron supplementation even after their levels normalized. This suggests that while iron treatment can benefit those suffering from anemia due to gastritis, it may not completely resolve the underlying issues for everyone. We also noted that repeat endoscopies did not reveal any significant changes in gastric histopathology, which indicates that while the symptoms could improve with treatment, the condition itself might not necessarily change.
Ultimately, our findings encourage healthcare professionals to consider CG and LG more seriously in pediatric patients, especially when treating related conditions like iron deficiency anemia.
9.5
Felt better
Most Useful Review
This iron supplement has been beneficial. I didn’t take tests initially, but I noticed improvements within a few weeks—less hair loss and overall better health. It does not irritate my gastritis as I take it after meals. It is cost-effective, lasting a long time, so I highly recommend it!
Fish Oil
8
DHA reduces H. pylori effects
Crosstalk between Helicobacter pylori and gastric epithelial cells is impaired by docosahexaenoic acid.
Most Relevant Research
We aimed to understand how docosahexaenoic acid (DHA) impacts the growth of Helicobacter pylori, a common bacteria linked to gastritis and other stomach disorders. Our research focused on how DHA influences bacterial adhesion to stomach cells and reduces inflammation associated with infection.
At concentrations of 100 µM, DHA effectively reduced H. pylori growth, while higher amounts of 250 µM or more led to irreversible effects on bacterial survival. We noted that DHA not only hindered bacterial growth but also decreased the bacteria's ability to attach to gastric epithelial cells. Moreover, we found that cells infected with DHA-treated H. pylori showed significantly lower levels of Interleukin-8 (IL-8), an inflammatory marker, alongside reductions in other inflammatory proteins.
Through our analysis, we discovered that DHA alters the outer membrane proteins of H. pylori, which are involved in its stress response and metabolism. These changes seem to contribute to lesser adhesion to stomach cells and a reduced inflammatory response. These findings suggest that DHA could be a beneficial alternative in managing H. pylori-related gastritis by targeting the bacteria and its effects on the stomach.
At concentrations of 100 µM, DHA effectively reduced H. pylori growth, while higher amounts of 250 µM or more led to irreversible effects on bacterial survival. We noted that DHA not only hindered bacterial growth but also decreased the bacteria's ability to attach to gastric epithelial cells. Moreover, we found that cells infected with DHA-treated H. pylori showed significantly lower levels of Interleukin-8 (IL-8), an inflammatory marker, alongside reductions in other inflammatory proteins.
Through our analysis, we discovered that DHA alters the outer membrane proteins of H. pylori, which are involved in its stress response and metabolism. These changes seem to contribute to lesser adhesion to stomach cells and a reduced inflammatory response. These findings suggest that DHA could be a beneficial alternative in managing H. pylori-related gastritis by targeting the bacteria and its effects on the stomach.
9.5
Reduced palpitations
Most Useful Review
Omega-3 has benefitted my cardiovascular and nervous systems. I began taking it to manage my hypertension along with coenzyme Q10. The capsules are sizeable but easy to swallow, and I’ve experienced no side effects so far. My strong palpitations disappeared, and my blood pressure has lowered, which is encouraging.