Enzymes
8
Nattokinase nanozyme aids heart recovery
A Nattokinase-Loaded Nanozyme for Alleviating Acute Myocardial Infarction via Thrombolysis and Antioxidation.
Most Relevant Research
We designed a study to explore the effectiveness of nattokinase in treating acute myocardial infarction, a condition often caused by blood clots. Thrombus formation leads to reduced blood flow, and finding effective treatments is critical for improving outcomes in heart attack patients.
Nattokinase is a naturally occurring enzyme known for its ability to dissolve blood clots, but its clinical use has been limited due to stability issues. To overcome this, we developed a manganese oxide nanozyme loaded with nattokinase, called MnOx@NK. This innovative approach not only delivers the clot-busting properties of nattokinase but also provides antioxidant benefits.
In our experiments using a mouse model of heart attack, we administered MnOx@NK through tail vein injections. The results were promising: we observed significant improvements in vascular function and a notable reduction in myocardial injury. The nanozyme effectively protected against oxidative stress, which can worsen the damage caused by heart attacks.
Overall, our findings suggest that using nattokinase-loaded nanozymes may pave the way for new treatments for acute myocardial infarction, potentially offering a safer and more effective option for patients facing this severe condition.
Nattokinase is a naturally occurring enzyme known for its ability to dissolve blood clots, but its clinical use has been limited due to stability issues. To overcome this, we developed a manganese oxide nanozyme loaded with nattokinase, called MnOx@NK. This innovative approach not only delivers the clot-busting properties of nattokinase but also provides antioxidant benefits.
In our experiments using a mouse model of heart attack, we administered MnOx@NK through tail vein injections. The results were promising: we observed significant improvements in vascular function and a notable reduction in myocardial injury. The nanozyme effectively protected against oxidative stress, which can worsen the damage caused by heart attacks.
Overall, our findings suggest that using nattokinase-loaded nanozymes may pave the way for new treatments for acute myocardial infarction, potentially offering a safer and more effective option for patients facing this severe condition.
9.5
No further heart attacks
Most Useful Review
I learned about nattokinase after my father was diagnosed with heart problems, having suffered a heart attack. We consulted his physician and switched to natural treatment with nattokinase. After a year, his blood circulation improved, and he hasn't had any further heart attacks. This truly is essential for heart patients.
Iron
9
Macrophage EVs combat iron overload
Macrophage-derived extracellular vesicles represent a promising endogenous iron-chelating therapy for iron overload and cardiac injury in myocardial infarction.
Most Relevant Research
We delved into the connection between iron overload and its effects on heart function after a heart attack, also known as myocardial infarction (MI). Our research focused on utilizing macrophage-derived extracellular vesicles (EVs) as a natural therapy to help with excessive iron levels in the heart.
The downside of existing chemical iron chelators is that they often come with side effects, so we sought a safer and more effective solution. By isolating EVs from macrophages, we found that they serve as a biological chelator for iron. When we introduced these EVs to heart cells affected by low oxygen levels, they significantly reduced iron overload and minimized the oxidative stress linked to this excess iron.
Notably, these EVs work by harnessing a receptor called transferrin receptor (TfR), which helps them grab onto and remove the surplus protein-bound iron. In our observations, when the EVs lacked TfR, they were ineffective in protecting heart tissue. This shows that leveraging macrophage-derived EVs could offer a new approach in treating heart damage due to iron overload, especially after myocardial infarction.
The downside of existing chemical iron chelators is that they often come with side effects, so we sought a safer and more effective solution. By isolating EVs from macrophages, we found that they serve as a biological chelator for iron. When we introduced these EVs to heart cells affected by low oxygen levels, they significantly reduced iron overload and minimized the oxidative stress linked to this excess iron.
Notably, these EVs work by harnessing a receptor called transferrin receptor (TfR), which helps them grab onto and remove the surplus protein-bound iron. In our observations, when the EVs lacked TfR, they were ineffective in protecting heart tissue. This shows that leveraging macrophage-derived EVs could offer a new approach in treating heart damage due to iron overload, especially after myocardial infarction.
9.5
Improved hemoglobin levels
Most Useful Review
The rescue! Three years ago, I struggled with treating my anaemia; my haemoglobin was stuck at 80. After taking this specific iron supplement for two years, my haemoglobin is now consistently 140. I no longer experience the headaches I used to, nor am I freezing like before. This product is irreplaceable for me.
Ubiquinol
9
Combination therapy improves heart health
Superior Anti-arrhythmogenic Effect of Combined Conditioning with Nicotinamide Mononucleotide and Ubiquinol in Myocardial Ischemia/Reperfusion Injury in Aged Rats.
Most Relevant Research
We examined the combined effects of nicotinamide mononucleotide (NMN) and ubiquinol on heart health, particularly focusing on how they impact lethal heart rhythms following a heart attack in aged rats. The study involved 30 male Wistar rats, including groups with and without myocardial ischemia/reperfusion injury, as well as those receiving either NMN, ubiquinol, or both.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
By administering NMN for a month before the heart attack and intravenously injecting ubiquinol during early reperfusion, we aimed to see how these treatments could reduce oxidative stress and improve nitric oxide levels. Our findings showed that the combination therapy had a notable anti-arrhythmic effect, helping to counteract the damaging heart rhythms often experienced after such serious incidents.
Although our research indicates that this combination treatment may offer better heart protection during aging, we recognize the need for more investigations to fully explore this potential and understand the precise effects of each component, particularly ubiquinol. Overall, our study highlights the promising role of combining therapies to enhance heart health in older adults.
9.5
Indispensable assistant
Most Useful Review
I regularly take ubiquinol every morning after a heart attack. It's proven effective for my heart defect and improves my energy levels and memory significantly. I no longer require other medications as this helps normalise my blood pressure. Although pricier, its benefits make it worthwhile.
Vitamin E
9
Selenium nanoparticles aid heart recovery
Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation.
Most Relevant Research
We investigated the potential of spherical selenium nanoparticles (SeNPs) to reduce the harmful effects of ischemia/reperfusion injury (I/RI) that often occurs after a heart attack. The study involved intravenous injections of these nanoparticles, which showcased impressive antioxidant and anti-inflammatory properties.
Our findings revealed that SeNPs effectively disrupted the harmful cycle of oxidative stress and inflammation associated with heart damage. They helped protect the heart cells by keeping mitochondrial functions intact and reducing programmed cell death, also known as apoptosis. Furthermore, SeNPs managed to lessen the invasion of inflammatory cells and reduce the release of harmful mediators during I/RI.
In practical terms, when tested in vivo, the selenium nanoparticles significantly improved heart function while reducing both cell death and tissue scarring. This indicates that these nanoparticles could offer a promising new approach to enhance treatments following heart attacks, specifically by focusing on the key pathway of STAT1, which plays a crucial role in mediating injury and inflammation.
Our findings revealed that SeNPs effectively disrupted the harmful cycle of oxidative stress and inflammation associated with heart damage. They helped protect the heart cells by keeping mitochondrial functions intact and reducing programmed cell death, also known as apoptosis. Furthermore, SeNPs managed to lessen the invasion of inflammatory cells and reduce the release of harmful mediators during I/RI.
In practical terms, when tested in vivo, the selenium nanoparticles significantly improved heart function while reducing both cell death and tissue scarring. This indicates that these nanoparticles could offer a promising new approach to enhance treatments following heart attacks, specifically by focusing on the key pathway of STAT1, which plays a crucial role in mediating injury and inflammation.
9.5
Protects against heart attack
Most Useful Review
Wonderful! The strongest antioxidant, 400 IU daily protects significantly against heart attack and improves overall health. It cleanses the blood of harmful fats, which enhances circulation and ensures good cholesterol remains unoxidised. Vitamin E is vital for reproductive health, delays menopause, alleviates symptoms of premenstrual syndrome, and promotes healthy internal organ function. I take it with omega acids for better absorption, and I've noticed smoother skin. I recommend consulting your doctor for advice.
Polygonum Cuspidatum Complex
8.8
Comprehensive benefits
Most Useful Review
I've recently started taking Resveratrol on a friend's suggestion. It significantly enhances blood vessel health, lowers cholesterol, and improves circulation. It effectively addresses issues like hypertension and aids with heart rhythm regulation. I enjoy taking it after meals.
10
Improved heart rhythm
Most Useful Review
Just superb! After taking this product for nearly two weeks, my ECG showed a normal sinus heart rate. Previously, I had arrhythmia, and this has brought about a great result!
Inositol
9
ITPP enhances heart attack recovery
Treatment of hypoxia-dependent cardiovascular diseases by myo-inositol trispyrophosphate (ITPP)-enhancement of oxygen delivery by red blood cells.
Most Relevant Research
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
9.5
Various benefits
Most Useful Review
Inositol is beneficial for numerous conditions, from diabetic nerve pain to high cholesterol and even polycystic ovary syndrome. It's been shown to help balance chemicals, aiding conditions like panic disorders and potentially reducing the risk of heart attack through improved cholesterol levels.
Quercetin
9.5
Allergy relief
Most Useful Review
Every year, I suffer from an allergy attack during Spring. After one day of taking Jarrow Quercetin, I felt better and now enjoy my first Spring in ages. It's like a miracle for me.
9.5
Supports heart health
Most Useful Review
I have been taking quercetin since September 2020. I use this drug alongside Quercetin from Paradise Herbs for my varicose veins, preparing for surgery. My recent ultrasound showed calm vessels without inflammation, and my heart scan was normal. After four cycles of chemotherapy, I believe this supplement, along with others, helped reduce my inflammation and support my heart. Be healthy and enjoy life!
Probiotics
9.5
β-Glucan shows cardioprotective effects
Pretreatment with β-glucan attenuates isoprenaline-induced myocardial injury in rats.
Most Relevant Research
We explored whether pretreatment with β-glucan, a compound from the yeast Saccharomyces cerevisiae, could shield against heart damage induced by isoprenaline in rats. Through a well-structured experiment involving control and treatment groups, we discovered that β-glucan significantly reduced heart strain by improving cardiac markers and minimizing harmful changes in heart tissue.
This suggests that β-glucan has the potential to aid in preventing damage from heart attacks. However, it’s essential to note that more research is needed to see if these promising results can translate to humans.
This suggests that β-glucan has the potential to aid in preventing damage from heart attacks. However, it’s essential to note that more research is needed to see if these promising results can translate to humans.
9.5
Restored energy levels
Most Useful Review
At 47, I've been experiencing heart palpitations and low energy. After using a high-grade liquid Magnesium, I found that combining it with "Heart and Body Extract" and this Garden of Life CoQ10 has revitalised my energy and improved my heart health significantly. I'm recommending both products enthusiastically!
Vitamin Bs
9
ITPP enhances heart attack recovery
Treatment of hypoxia-dependent cardiovascular diseases by myo-inositol trispyrophosphate (ITPP)-enhancement of oxygen delivery by red blood cells.
Most Relevant Research
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
9.5
Reduced heart disease risk
Most Useful Review
My blood test showed elevated homocysteine, which can lead to heart attacks. I was prescribed Methylfolate, and after two weeks of taking 4000 mcg, my levels dropped from 14 to 5.8. Remember, high homocysteine can damage blood vessels. Stay healthy!
L Lysine
9.5
Stopped outbreaks
Most Useful Review
I’ve struggled with herpes for ages, but this L-Lysine amino acid has halted my recurrent attacks. Just one pill daily significantly helps me, and it also benefits my immunity.
9.5
Boosted my health
Most Useful Review
An excellent drug! I had tingling sensations linked to a heart attack for a month. After purchasing this drug, my symptoms vanished within just five days. I took three capsules a day before meals, and the issues disappeared swiftly. I feel revitalised! I'm continuing the course but now at two capsules a day. Highly recommend!
Garlic
8
Garlic's allicin aids heart recovery
Metagenomic Sequencing Combined with Metabolomics to Explore Gut Microbiota and Metabolic Changes in Mice with Acute Myocardial Infarction and the Potential Mechanism of Allicin.
Most Relevant Research
We induced acute myocardial infarction (AMI) in mice to investigate the impact of allicin, a key component of garlic, on heart health. Over 28 days, we administered allicin orally while monitoring various factors such as heart function and inflammation through echocardiography and other tests.
Our findings revealed that allicin significantly eased myocardial injury, reducing markers of inflammation and improving heart function. It did this by inhibiting certain pathways associated with inflammation and remodeling gut microbiota, which plays a role in overall health.
Essentially, we found that allicin not only supports heart recovery but also enhances intestinal barrier health and improves metabolic balance. This discovery opens up exciting avenues for allicin to be considered as a supplementary treatment alongside conventional therapies for heart attacks.
Our findings revealed that allicin significantly eased myocardial injury, reducing markers of inflammation and improving heart function. It did this by inhibiting certain pathways associated with inflammation and remodeling gut microbiota, which plays a role in overall health.
Essentially, we found that allicin not only supports heart recovery but also enhances intestinal barrier health and improves metabolic balance. This discovery opens up exciting avenues for allicin to be considered as a supplementary treatment alongside conventional therapies for heart attacks.
9.5
Controls heart issues
Most Useful Review
Excellent garlic! My husband uses it for his tachycardia. The garlic combined with hawthorn and Q10 effectively alleviates all his symptoms and regulates his blood pressure.
Vitamin K2
9
Menaquinone-4 aids heart recovery
Potential Cardioprotective Role of Menaquinone-4 Against Cardiac Ischemia-reperfusion Injury.
Most Relevant Research
We examined how Menaquinone-4, a form of vitamin K2, could help protect the heart during a critical event known as ischemia-reperfusion (I/R) injury, which often occurs after heart attacks. In our study, we used thirty-two rats, dividing them into three groups: a control group that experienced I/R without treatment, a group that received MK-4 before the injury, and another group that got MK-4 at the beginning of the recovery phase.
By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.
Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.
By using a specialized apparatus to assess heart function, we measured various indicators of heart health, including the pressure the heart could generate and rates of heart contractions. We also examined markers of heart damage and stress, like enzymes and inflammatory signals.
Our findings were promising. The group that received MK-4 after the I/R injury showed a significant reduction in the size of heart damage, alongside improved heart function. This group also had lower levels of markers related to heart stress and damage, indicating that MK-4 might help the heart recover from the stress of a heart attack. Overall, these results suggest that vitamin K2 could be a valuable ally in enhancing heart health during recovery from ischemic events.
9.5
Improved artery health
Most Useful Review
It works for dental health. After having a heart attack in February 2018 with significant artery blockages, I adopted a strict plant-based diet for eight months and took four pills of this product and two of vitamin D3 daily. A recent calcium scoring CT scan revealed that my left artery plaque has reduced to moderate, with the other arteries clear of plaque. Praise the Lord.
Flax Seed Oil
9.5
Vegan heart support
Most Useful Review
This flax oil product has immensely benefited my hair and heart health by lowering my cholesterol and inflammation due to the omegas. As a vegan, I appreciate that I don’t have to take fish oil or deal with a fishy aftertaste!
9.5
Doctor recommended
Most Useful Review
My doctor recommended flaxseed oil for improving blood vessel elasticity and detoxification. Our entire family has now ordered it.
9.5
Fights heart attack
Most Useful Review
Best toothpaste! I was a bit anxious trying this initially as I thought it might taste unpleasant. It doesn't have much flavour but works brilliantly! My teeth feel incredibly clean, as if I just had them done at the dentist. With regular toothpaste, I noticed tartar build-up, but using xylitol in this toothpaste effectively helps fight tartar related to heart attack.
9.5
Prevents heart attack
Most Useful Review
May God grant everyone goodness. This is the best toothpaste I've used—excellent quality with a gentle flavour that doesn’t induce nausea, unlike others I've tried. It’s effective for sensitive teeth and cleans brilliantly without causing discomfort.
Coconut Oil
9.5
Easier heart support
Most Useful Review
The quality of these Extra Virgin Coconut Oil 1,000 mg capsules is excellent. They are a fantastic addition to my routine, providing the benefits of coconut oil, such as skin hydration and supporting heart health, without the mess of liquid form.
8.8
Heart protection noted
Most Useful Review
I took this for heart and brain issues. It seems to protect against harmful cholesterol and may stimulate brain function. I hope it benefits me and prevents a heart attack.
Vitamins
4
Vitamin D deficiency and heart attacks
Association of Vitamin D Deficiency as an Independent Risk Factor for Myocardial Infarction and Its Therapeutic Implications: A Systematic Review.
Most Relevant Research
We explored the intriguing connection between vitamin D deficiency and the risk of heart attacks, specifically myocardial infarctions (MIs). Numerous studies suggest that low levels of vitamin D might play a role in developing coronary artery disease, which is a leading cause of MI. It's noteworthy that vitamin D isn't just important for bone health; it appears to have protective effects on the heart as well.
We observed patterns from various observational studies that show a correlation between low vitamin D levels and an increased incidence of heart attacks. Additionally, vitamin D deficiency may lead to post-infarction complications and contribute to harmful cardiac remodeling. However, while the potential benefits of vitamin D seem promising, the exact impact of vitamin D supplementation on reducing heart attack risk is still inconclusive, as many interventional studies yielded mixed results.
Ultimately, we recognize that vitamin D deficiency is manageable and that assessing and treating this deficiency could be pivotal, especially for individuals who experience acute myocardial infarction. Future research is therefore essential to clarify whether vitamin D supplementation can effectively reduce heart attack risks and to determine appropriate dosing and long-term effects on heart health.
We observed patterns from various observational studies that show a correlation between low vitamin D levels and an increased incidence of heart attacks. Additionally, vitamin D deficiency may lead to post-infarction complications and contribute to harmful cardiac remodeling. However, while the potential benefits of vitamin D seem promising, the exact impact of vitamin D supplementation on reducing heart attack risk is still inconclusive, as many interventional studies yielded mixed results.
Ultimately, we recognize that vitamin D deficiency is manageable and that assessing and treating this deficiency could be pivotal, especially for individuals who experience acute myocardial infarction. Future research is therefore essential to clarify whether vitamin D supplementation can effectively reduce heart attack risks and to determine appropriate dosing and long-term effects on heart health.
9.5
No panic attacks
Most Useful Review
I take it alongside c-1000 and iron for panic attacks. I'm pleased to report that since starting this regimen, I have not experienced any panic attacks.
Evening Primrose
9
Aids heart function
Most Useful Review
Great! The product's rich composition includes polyacids and vitamins, promoting heart health and preventing heart attacks. Evening primrose oil has improved my wellness, supports my reproductive system, and even helps with skin and hair problems.
9
Heart health benefits
Most Useful Review
Excellent health! The quality is suitable. I've noticed significant improvements over time- it's beneficial for heart health and reduces arthritis symptoms. I liked it, and the taste is non-existent.
Taurine
8
Taurine reduces heart inflammation
Taurine Alleviates Sympathetic Innervation by Inhibiting NLRP3 Inflammasome in Postinfarcted Rats.
Most Relevant Research
We explored whether taurine, a compound known as 2-aminoethanesulphonic acid, could help improve heart recovery after a heart attack. Using a rat model, we looked at its effects on cardiac sympathetic reinnervation, which is a process triggered by inflammation following a myocardial infarction.
In our study, we divided male Wistar rats into groups receiving either saline or taurine after undergoing coronary ligation. The results were noteworthy: taurine treatment was associated with a significant reduction in various inflammatory markers, including NLRP3 inflammasome components and the protein IL-1β, which is linked to nerve growth factor (NGF) synthesis.
We found that taurine helped to blunt excessive sympathetic reinnervation, thereby decreasing the vulnerability to arrhythmias, a common concern after heart attacks. Additionally, our ex vivo studies showed that taurine effectively lowered myocardial IL-1β levels, similar to known inhibitors of inflammation. This suggests that taurine may exert its protective effects through suppression of the inflammasome and associated pathways.
Overall, taurine appears to offer promising anti-inflammatory benefits, potentially easing heart recovery after a heart attack through modulation of sympathetic innervation and nerve growth factors. These findings could pave the way for new therapeutic approaches in heart disease management.
In our study, we divided male Wistar rats into groups receiving either saline or taurine after undergoing coronary ligation. The results were noteworthy: taurine treatment was associated with a significant reduction in various inflammatory markers, including NLRP3 inflammasome components and the protein IL-1β, which is linked to nerve growth factor (NGF) synthesis.
We found that taurine helped to blunt excessive sympathetic reinnervation, thereby decreasing the vulnerability to arrhythmias, a common concern after heart attacks. Additionally, our ex vivo studies showed that taurine effectively lowered myocardial IL-1β levels, similar to known inhibitors of inflammation. This suggests that taurine may exert its protective effects through suppression of the inflammasome and associated pathways.
Overall, taurine appears to offer promising anti-inflammatory benefits, potentially easing heart recovery after a heart attack through modulation of sympathetic innervation and nerve growth factors. These findings could pave the way for new therapeutic approaches in heart disease management.
9.5
Heart health improvement
Most Useful Review
Excellent for heart health! My heart was skipping beats due to arrhythmia, but I’ve observed a 90% improvement since starting this product.
Herbal Extracts
7.5
Pain alleviation
Most Useful Review
I got Ginkgo for my father-in-law post-heart surgery, and I've noticed visible improvements. The pain in his back has disappeared, and he no longer has subcutaneous bruises. His blood vessels seem stronger, so I highly recommend this product.
9.5
Heart problems improved
Most Useful Review
I took it to my husband, who had heart problems and arrhythmias after coronavirus. He has been drinking it for a week, and his heart beats normally now. I haven't tried it myself, but I plan to take it as my vessels are also damaged from the virus. I bought it on my brother's recommendation; he is a dermato-venereologist, and I have heard it’s a remarkable remedy.
Cacao
8.8
Natural antidepressant
Most Useful Review
Delicious and beneficial! I've been eagerly awaiting this raw cocoa, which I consider a superfood. It’s great for heart health and lowers blood pressure. Additionally, it stimulates brain activity and lifts the mood by increasing endorphins. Its antioxidant properties make it more potent than other superfoods. With its “USDA Organic” certification, it’s purely organic without harmful pesticides. Enjoy shopping!
8.8
Improves blood circulation
Most Useful Review
Cocoa is excellent for elevating mood! I bought it for my daughter to make healthy candies on my diet. The flavonoids in cocoa enhance blood circulation, lower blood pressure, and positively affect heart function. It boosts brain function and helps increase endorphins and serotonin for better mood. I also liked the packaging.
Potassium
8
Potassium levels influence heart attack outcomes
Association between potassium fluctuation and in-hospital mortality in acute myocardial infarction patients: a retrospective analysis of the MIMIC-IV database.
Most Relevant Research
We investigated the crucial link between potassium levels and mortality rates among patients who suffered an acute myocardial infarction, commonly known as a heart attack. Through a thorough analysis of data from the MIMIC-IV database, which included patient information from the Beth Israel Deaconess Medical Center between 2008 and 2022, we looked closely at how fluctuations in serum potassium might affect outcomes.
By examining various measures of potassium, including average levels after admission and changes in those levels, we aimed to understand their relationship with in-hospital mortality and other serious complications such as cardiac arrest. Our findings revealed that fluctuations in potassium levels are significant predictors of in-hospital mortality for heart attack patients. This emphasizes the importance of keeping potassium levels stable as a part of effective heart attack management.
Overall, our research supports the idea that monitoring and managing potassium levels can be vital in improving outcomes for patients experiencing heart attacks. These insights can help guide treatments and protocols, potentially saving lives in the process.
By examining various measures of potassium, including average levels after admission and changes in those levels, we aimed to understand their relationship with in-hospital mortality and other serious complications such as cardiac arrest. Our findings revealed that fluctuations in potassium levels are significant predictors of in-hospital mortality for heart attack patients. This emphasizes the importance of keeping potassium levels stable as a part of effective heart attack management.
Overall, our research supports the idea that monitoring and managing potassium levels can be vital in improving outcomes for patients experiencing heart attacks. These insights can help guide treatments and protocols, potentially saving lives in the process.
9.5
Improved energy levels
Most Useful Review
This potassium citrate is excellent! After suffering from a heart attack and enduring significant fatigue and weakness, I started taking potassium citrate on my doctor's advice. It has greatly improved my energy and memory, and most importantly, my heart no longer hurts. I take 3-4 capsules daily and plan to reorder. I highly recommend this miracle potassium citrate.
Fish Oil
9
Omega-3s reduce heart attack risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We examined the effects of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on the risk of heart attacks through a comprehensive analysis of the VITAL trial. This significant study included nearly 26,000 older adults in the U.S. who were monitored over an average of 5.3 years.
The original trial didn't find significant results for major cardiovascular events overall, but our Bayesian analysis suggested a different insight. By incorporating previous research and evidence, we discovered that daily supplementation with EPA appears to notably lower the risk of coronary heart disease events, particularly heart attacks.
However, the same beneficial effects did not extend to strokes or overall cardiovascular death, which means while we do see an encouraging trend for heart attacks, the evidence doesn't support a broad impact on other cardiovascular-related issues. Our findings help reinforce the value of omega-3 fatty acid supplementation as a preventive measure specifically for heart attacks.
The original trial didn't find significant results for major cardiovascular events overall, but our Bayesian analysis suggested a different insight. By incorporating previous research and evidence, we discovered that daily supplementation with EPA appears to notably lower the risk of coronary heart disease events, particularly heart attacks.
However, the same beneficial effects did not extend to strokes or overall cardiovascular death, which means while we do see an encouraging trend for heart attacks, the evidence doesn't support a broad impact on other cardiovascular-related issues. Our findings help reinforce the value of omega-3 fatty acid supplementation as a preventive measure specifically for heart attacks.
9.5
Heart attack prevention
Most Useful Review
I drink Omega-3 with lecithin, and it has significantly improved my heart health and sleep quality. At my age, staying well is crucial. My family has long-lived members, and I intend to live longer for my grandchildren. I highly recommend Omega-3!
Protein
9
Nanoparticle delivery improves heart recovery
Targeted delivery of TAPI-1 via biomimetic nanoparticles ameliorates post-infarct left ventricle function and remodeling.
Most Relevant Research
We explored the potential of TAPI-1, a protein that inhibits harmful enzymes, in treating heart damage after a heart attack, using a novel delivery method. To enhance its effectiveness, researchers created nanoparticles that mimic neutrophils, a type of immune cell that quickly appears in injured heart tissue.
These specialized nanoparticles were loaded with TAPI-1 and specifically designed to target inflamed areas of the heart in rats following a heart attack. By delivering TAPI-1 more precisely, we aimed to reduce heart injury and improve heart function.
Our results were promising—injecting TAPI-1 through these neutrophil-mimicking nanoparticles led to better heart performance and less scar tissue compared to standard TAPI-1 treatments. Not only did the targeted approach seem to optimize the protein's effects, but it also helped lessen the overall inflammation within the heart.
In summary, this study highlights a strategic advancement in delivering the TAPI-1 protein that could lead to more effective treatments for heart attack recovery, ultimately improving patient outcomes.
These specialized nanoparticles were loaded with TAPI-1 and specifically designed to target inflamed areas of the heart in rats following a heart attack. By delivering TAPI-1 more precisely, we aimed to reduce heart injury and improve heart function.
Our results were promising—injecting TAPI-1 through these neutrophil-mimicking nanoparticles led to better heart performance and less scar tissue compared to standard TAPI-1 treatments. Not only did the targeted approach seem to optimize the protein's effects, but it also helped lessen the overall inflammation within the heart.
In summary, this study highlights a strategic advancement in delivering the TAPI-1 protein that could lead to more effective treatments for heart attack recovery, ultimately improving patient outcomes.
9
Promotes heart health
Most Useful Review
Excellent product! Pumpkin seeds are a delightful, crunchy snack that enhances my diet. They offer many health benefits, including heart health and digestion improvement. I recommend them for their rich nutrients and great taste.
L Carnitine
8
L-Carnitine's potential in heart attacks
Neuroprotective effects of L-carnitine towards oxidative stress and inflammatory processes: a review of its importance as a therapeutic drug in some disorders.
Most Relevant Research
Our inquiry into the effects of L-carnitine (LC) on heart attacks reveals some promising insights. LC, a natural compound known for its role in energy production and reduction of inflammation, has shown potential benefits in patients experiencing cardiac events. While the specifics of study methodologies were not detailed in the literature reviewed, we noted findings that suggest LC treatment might decrease inflammation and oxidative stress during heart-related incidents.
Furthermore, in instances of acute myocardial infarction, LC treatment was observed to improve both neurological and cardiac functions. This is particularly notable as it indicates that LC could play a supportive role in recovery post-heart attack. However, the discussion surrounding LC’s efficacy remains nuanced. The evidence hints at its effects, but it is still unclear if these are due to isolated usage of LC or in tandem with other treatments.
Overall, the implications of L-carnitine in cardiovascular health are intriguing but warrant cautious interpretation. Further studies with clear control and methodology are needed to clarify its benefits fully. This would help establish LC as a consistent therapeutic option in managing heart attack outcomes.
Furthermore, in instances of acute myocardial infarction, LC treatment was observed to improve both neurological and cardiac functions. This is particularly notable as it indicates that LC could play a supportive role in recovery post-heart attack. However, the discussion surrounding LC’s efficacy remains nuanced. The evidence hints at its effects, but it is still unclear if these are due to isolated usage of LC or in tandem with other treatments.
Overall, the implications of L-carnitine in cardiovascular health are intriguing but warrant cautious interpretation. Further studies with clear control and methodology are needed to clarify its benefits fully. This would help establish LC as a consistent therapeutic option in managing heart attack outcomes.
9.5
Heart support
Most Useful Review
After suffering from congestive heart failure, I used this product to regain my strength upon resuming exercise. It has genuinely supported my heart health, and I've felt significantly better after four years of consistent use.
Eicosapentaenoic Acid
9
Omega-3s reduce heart attack risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We examined the effects of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on the risk of heart attacks through a comprehensive analysis of the VITAL trial. This significant study included nearly 26,000 older adults in the U.S. who were monitored over an average of 5.3 years.
The original trial didn't find significant results for major cardiovascular events overall, but our Bayesian analysis suggested a different insight. By incorporating previous research and evidence, we discovered that daily supplementation with EPA appears to notably lower the risk of coronary heart disease events, particularly heart attacks.
However, the same beneficial effects did not extend to strokes or overall cardiovascular death, which means while we do see an encouraging trend for heart attacks, the evidence doesn't support a broad impact on other cardiovascular-related issues. Our findings help reinforce the value of omega-3 fatty acid supplementation as a preventive measure specifically for heart attacks.
The original trial didn't find significant results for major cardiovascular events overall, but our Bayesian analysis suggested a different insight. By incorporating previous research and evidence, we discovered that daily supplementation with EPA appears to notably lower the risk of coronary heart disease events, particularly heart attacks.
However, the same beneficial effects did not extend to strokes or overall cardiovascular death, which means while we do see an encouraging trend for heart attacks, the evidence doesn't support a broad impact on other cardiovascular-related issues. Our findings help reinforce the value of omega-3 fatty acid supplementation as a preventive measure specifically for heart attacks.
9.5
Asthma relief
Most Useful Review
My daughter's asthma symptoms improved remarkably after two weeks of taking cod liver oil. Prior to this, she experienced severe coughing and had to be rushed to the hospital. Now, she only has occasional flare-ups. I appreciate Nordic Naturals for their high processing standards and safety for children.
Coenzyme Q10
9
Coenzyme Q10 mitigates heart attack effects
Therapeutic effect of coenzyme-Q10 pretreatment on isoprenaline-induced cardiogenic hepatorenal complications in rats.
Most Relevant Research
We explored the connection between acute heart attacks and potential liver and kidney complications, specifically focusing on the role of coenzyme Q10 (Q10). In our study, we examined male rats divided into groups—some receiving normal saline and others pretreated with Q10 for 28 days, followed by an induced heart attack using isoprenaline (ISO).
Our findings revealed that ISO administration increased oxidative stress and negatively affected liver and kidney health. However, those pretreated with Q10 showed notable protection against both biochemical and tissue changes linked to these complications. We observed significantly improved antioxidant levels and a reduction in harmful liver and kidney enzymes. Furthermore, the histopathological examination indicated less severe damage in the tissues of the rats given Q10 compared to those that received ISO alone.
Overall, this study suggests that coenzyme Q10 may help shield the liver and kidneys during recovery from a heart attack by counteracting oxidative stress and reducing fibrotic changes. This finding highlights the potential of Q10 as a supportive treatment during critical cardiac events.
Our findings revealed that ISO administration increased oxidative stress and negatively affected liver and kidney health. However, those pretreated with Q10 showed notable protection against both biochemical and tissue changes linked to these complications. We observed significantly improved antioxidant levels and a reduction in harmful liver and kidney enzymes. Furthermore, the histopathological examination indicated less severe damage in the tissues of the rats given Q10 compared to those that received ISO alone.
Overall, this study suggests that coenzyme Q10 may help shield the liver and kidneys during recovery from a heart attack by counteracting oxidative stress and reducing fibrotic changes. This finding highlights the potential of Q10 as a supportive treatment during critical cardiac events.
9.5
Cessation of arrhythmia
Most Useful Review
After my mother suffered a heart attack, she began taking Coenzyme Q10. Initially at 60-90 mg daily, her arrhythmia attacks ceased after 5 months. For two years, she has continued with 100 mg daily, resulting in noticeable health improvements. I started taking Q10 at 50 mg daily, feeling more energetic and noticing improved gum health. This product has transformed our lives, and friends have also begun taking it based on our experience.
Red Yeast Rice
9
Coenzyme Q10 mitigates heart attack effects
Therapeutic effect of coenzyme-Q10 pretreatment on isoprenaline-induced cardiogenic hepatorenal complications in rats.
Most Relevant Research
We explored the connection between acute heart attacks and potential liver and kidney complications, specifically focusing on the role of coenzyme Q10 (Q10). In our study, we examined male rats divided into groups—some receiving normal saline and others pretreated with Q10 for 28 days, followed by an induced heart attack using isoprenaline (ISO).
Our findings revealed that ISO administration increased oxidative stress and negatively affected liver and kidney health. However, those pretreated with Q10 showed notable protection against both biochemical and tissue changes linked to these complications. We observed significantly improved antioxidant levels and a reduction in harmful liver and kidney enzymes. Furthermore, the histopathological examination indicated less severe damage in the tissues of the rats given Q10 compared to those that received ISO alone.
Overall, this study suggests that coenzyme Q10 may help shield the liver and kidneys during recovery from a heart attack by counteracting oxidative stress and reducing fibrotic changes. This finding highlights the potential of Q10 as a supportive treatment during critical cardiac events.
Our findings revealed that ISO administration increased oxidative stress and negatively affected liver and kidney health. However, those pretreated with Q10 showed notable protection against both biochemical and tissue changes linked to these complications. We observed significantly improved antioxidant levels and a reduction in harmful liver and kidney enzymes. Furthermore, the histopathological examination indicated less severe damage in the tissues of the rats given Q10 compared to those that received ISO alone.
Overall, this study suggests that coenzyme Q10 may help shield the liver and kidneys during recovery from a heart attack by counteracting oxidative stress and reducing fibrotic changes. This finding highlights the potential of Q10 as a supportive treatment during critical cardiac events.
8.3
Lowering cholesterol
Most Useful Review
Red yeast rice is often used by those unable to tolerate statins. It may also lower coenzyme Q10 levels, so supplementation with ubiquinol is advisable. I took red yeast rice for my cholesterol, which was almost three times higher than normal. After two months, my cholesterol levels dropped significantly, although the results might not be immediate. I feel hopeful and will continue with this supplement, planning to order more. Retesting will provide more insight into its effectiveness in preventing heart attack.
Cod Liver Oil
9
DHA promotes heart recovery post-MI
Docosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway.
Most Relevant Research
We investigated how docosahexaenoic acid (DHA), a key component found in cod liver oil, might help in recovery after a heart attack. Our study utilized models of heart injury, including cultured heart cells and living mice, to observe the influence of DHA on heart health.
We found that DHA significantly enhanced the survival of heart cells exposed to low oxygen levels, a common condition after a heart attack. Additionally, in mice suffering from heart attacks, DHA reduced the heart’s damaged area and improved overall heart function while lessening scarring in the heart tissue.
One of the exciting findings was how DHA promoted autophagy—the body's way of cleaning out damaged cells—by activating a specific signaling pathway known as AMPK/mTOR. Blocking this autophagy process with an inhibitor diminished DHA's protective benefits, indicating that enhancing autophagy is a crucial way DHA helps the heart recover.
Our findings highlight that DHA can play an invaluable role in addressing heart damage following a heart attack, potentially offering a new avenue for treatment.
We found that DHA significantly enhanced the survival of heart cells exposed to low oxygen levels, a common condition after a heart attack. Additionally, in mice suffering from heart attacks, DHA reduced the heart’s damaged area and improved overall heart function while lessening scarring in the heart tissue.
One of the exciting findings was how DHA promoted autophagy—the body's way of cleaning out damaged cells—by activating a specific signaling pathway known as AMPK/mTOR. Blocking this autophagy process with an inhibitor diminished DHA's protective benefits, indicating that enhancing autophagy is a crucial way DHA helps the heart recover.
Our findings highlight that DHA can play an invaluable role in addressing heart damage following a heart attack, potentially offering a new avenue for treatment.
9.5
Enhanced clarity
Most Useful Review
After taking this, I notice my thoughts are clearer and I have better memory retention. Norwegian snow cod liver oil is highly beneficial for lowering cholesterol and protecting against heart attack. I strongly recommend it for its numerous benefits.
Omega 3
9
Omega-3s reduce heart attack risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We examined the effects of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on the risk of heart attacks through a comprehensive analysis of the VITAL trial. This significant study included nearly 26,000 older adults in the U.S. who were monitored over an average of 5.3 years.
The original trial didn't find significant results for major cardiovascular events overall, but our Bayesian analysis suggested a different insight. By incorporating previous research and evidence, we discovered that daily supplementation with EPA appears to notably lower the risk of coronary heart disease events, particularly heart attacks.
However, the same beneficial effects did not extend to strokes or overall cardiovascular death, which means while we do see an encouraging trend for heart attacks, the evidence doesn't support a broad impact on other cardiovascular-related issues. Our findings help reinforce the value of omega-3 fatty acid supplementation as a preventive measure specifically for heart attacks.
The original trial didn't find significant results for major cardiovascular events overall, but our Bayesian analysis suggested a different insight. By incorporating previous research and evidence, we discovered that daily supplementation with EPA appears to notably lower the risk of coronary heart disease events, particularly heart attacks.
However, the same beneficial effects did not extend to strokes or overall cardiovascular death, which means while we do see an encouraging trend for heart attacks, the evidence doesn't support a broad impact on other cardiovascular-related issues. Our findings help reinforce the value of omega-3 fatty acid supplementation as a preventive measure specifically for heart attacks.
8
Supports heart function
Most Useful Review
Jarrow Omega-3 offers highly refined omega-3 fatty acids from fish oil, promoting heart and brain health, as well as joint health. I recommend it highly; I take it regularly.
Selenium
9
Selenium nanoparticles aid heart recovery
Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation.
Most Relevant Research
We investigated the potential of spherical selenium nanoparticles (SeNPs) to reduce the harmful effects of ischemia/reperfusion injury (I/RI) that often occurs after a heart attack. The study involved intravenous injections of these nanoparticles, which showcased impressive antioxidant and anti-inflammatory properties.
Our findings revealed that SeNPs effectively disrupted the harmful cycle of oxidative stress and inflammation associated with heart damage. They helped protect the heart cells by keeping mitochondrial functions intact and reducing programmed cell death, also known as apoptosis. Furthermore, SeNPs managed to lessen the invasion of inflammatory cells and reduce the release of harmful mediators during I/RI.
In practical terms, when tested in vivo, the selenium nanoparticles significantly improved heart function while reducing both cell death and tissue scarring. This indicates that these nanoparticles could offer a promising new approach to enhance treatments following heart attacks, specifically by focusing on the key pathway of STAT1, which plays a crucial role in mediating injury and inflammation.
Our findings revealed that SeNPs effectively disrupted the harmful cycle of oxidative stress and inflammation associated with heart damage. They helped protect the heart cells by keeping mitochondrial functions intact and reducing programmed cell death, also known as apoptosis. Furthermore, SeNPs managed to lessen the invasion of inflammatory cells and reduce the release of harmful mediators during I/RI.
In practical terms, when tested in vivo, the selenium nanoparticles significantly improved heart function while reducing both cell death and tissue scarring. This indicates that these nanoparticles could offer a promising new approach to enhance treatments following heart attacks, specifically by focusing on the key pathway of STAT1, which plays a crucial role in mediating injury and inflammation.
8.8
Boosted immunity
Most Useful Review
Selenium is essential for health! I've been taking it for autoimmune thyroiditis as prescribed by my doctor. It strengthens my immunity and overall well-being. One capsule daily prepares me for any challenge. I trust NOW products, and this specific selenium supplement has been effective. It serves various functions including antioxidant action, support for the immune system, and heart health, which is vital given the risk of heart attack.
Calcium
9
Calcium's role in heart regeneration
Pharmacological or genetic inhibition of LTCC promotes cardiomyocyte proliferation through inhibition of calcineurin activity.
Most Relevant Research
We explored how calcium signaling influences heart cell proliferation, particularly after injuries like heart attacks. Our study centered on the L-Type Calcium Channel (LTCC) and how its inhibition might help heart cells regenerate. Remarkably, when we inhibited LTCC—either through pharmacological means or by enhancing the activity of an inherent inhibitor called RRAD—we observed significant boosts in heart cell activity.
This process appears connected to calcineurin activity, a key player in cell signaling. By carefully manipulating these pathways, we managed to not only provoke heart cell growth in lab settings but also improve heart function and reduce scar tissue in live animal models post-heart attack.
Through our findings, we highlight the potential for new calcium-related treatments that could significantly benefit patients with heart injury, paving the way for exciting advancements in regenerative medicine. By understanding this intricate relationship between calcium signaling and heart cell growth, we open doors for innovative therapies that could transform recovery strategies in cardiovascular care.
This process appears connected to calcineurin activity, a key player in cell signaling. By carefully manipulating these pathways, we managed to not only provoke heart cell growth in lab settings but also improve heart function and reduce scar tissue in live animal models post-heart attack.
Through our findings, we highlight the potential for new calcium-related treatments that could significantly benefit patients with heart injury, paving the way for exciting advancements in regenerative medicine. By understanding this intricate relationship between calcium signaling and heart cell growth, we open doors for innovative therapies that could transform recovery strategies in cardiovascular care.
9.5
Heart pain relief
Most Useful Review
Super! I have a small child, and with sleepless nights, my heart ached from fatigue. After consulting a cardiologist, I began taking Calcium, Magnesium, and Zinc, which stopped my heart from hurting. I highly recommend this preparation, though it can be hard to find; I will purchase it again.
Magnesium
7
Magnesium levels linked to CIN
The Role of Magnesium Levels in the Progression of Contrast-Induced Nephropathy in Patients With STEMI Undergoing Primary PCI.
Most Relevant Research
We investigated the role of magnesium in the development of contrast-induced nephropathy (CIN) following primary percutaneous coronary intervention (pPCI) in patients suffering from ST-Elevation Myocardial Infarction (STEMI). In our study involving over 2,300 STEMI patients, we found that 30% developed CIN after their procedure. Analyzing the magnesium levels present at admission, we observed that those who experienced CIN had significantly lower magnesium levels compared to those who didn't.
Our findings revealed that magnesium levels below 2.03 mg/dL were linked to an increased risk of developing CIN, alongside other factors like age over 68 years and reduced left ventricular function. We identified this magnesium cutoff through rigorous analysis, demonstrating that low levels of this mineral can be a significant indicator of risk in heart attack patients following a procedure. This insight emphasizes the potential importance of monitoring magnesium levels to help predict and possibly prevent CIN in these vulnerable patients.
Our findings revealed that magnesium levels below 2.03 mg/dL were linked to an increased risk of developing CIN, alongside other factors like age over 68 years and reduced left ventricular function. We identified this magnesium cutoff through rigorous analysis, demonstrating that low levels of this mineral can be a significant indicator of risk in heart attack patients following a procedure. This insight emphasizes the potential importance of monitoring magnesium levels to help predict and possibly prevent CIN in these vulnerable patients.
9.5
Supports heart function
Most Useful Review
Following a heart attack, magnesium has been very beneficial for my body in maintaining normal cardiovascular function. I now take this supplement regularly to prevent future issues.
L Theanine
9
ITPP enhances heart attack recovery
Treatment of hypoxia-dependent cardiovascular diseases by myo-inositol trispyrophosphate (ITPP)-enhancement of oxygen delivery by red blood cells.
Most Relevant Research
We explored the potential of myo-inositol trispyrophosphate (ITPP) as a treatment for heart attacks and its effect on heart tissue injured by low oxygen levels. This research indicates ITPP modifies hemoglobin in red blood cells, enhancing the delivery of oxygen throughout the body.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
Using an animal model for myocardial infarction, we observed that ITPP administration provided significant protection against heart failure and aided in recovery from left ventricular remodeling following the heart attack.
In our laboratory studies, heart muscle cells exposed to low oxygen levels reacted quickly to ITPP treatment, showing increased activity of a protein known as HIF-1. Interestingly, this overactivity was countered by ITPP when it was in the red blood cells, which suggests a strong connection between shear stress from blood flow and oxygen release facilitated by the modified hemoglobin.
Overall, the findings indicate that ITPP could be a game-changer in treating injuries to heart tissues related to low oxygen or ischemia. This approach may open new avenues for effectively managing damage caused by heart attacks.
8.3
Normalised pulse
Most Useful Review
This is an excellent calming aid and has notably reduced my high heart rate. I take it nightly with bacopa, and I've been sleeping better, waking up less frequently. My pulse is now normal. I appreciate this product.
Lutein
8
Lutein lowers heart attack risk
The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population.
Most Relevant Research
We investigated the relationship between serum carotenoids, like lutein, and the risk of cardiovascular disease (CVD) using data from a nationwide survey of over 12,000 adults.
Our analysis revealed that higher levels of lutein, along with other carotenoids, were linked to lower rates of CVD, especially heart attacks and strokes.
This suggests that increasing carotenoid concentrations could serve as a protective factor against serious cardiovascular events.
Our analysis revealed that higher levels of lutein, along with other carotenoids, were linked to lower rates of CVD, especially heart attacks and strokes.
This suggests that increasing carotenoid concentrations could serve as a protective factor against serious cardiovascular events.
8.8
Improved heart health
Most Useful Review
Trusted brand and a wonderful antioxidant supplement for eye health. Research shows that Lutein and Zeaxanthin can help reverse cataracts and significantly enhance glaucoma. It's an investment worth making.
Melatonin
8.8
Improved sleep quality
Most Useful Review
Improved sleep and life quality. It's been a lifesaver! I struggle with chronic pain due to osteoarthritis and fibromyalgia, making sleep difficult. With a weak heart, being overtired affects my health severely. Previously, I had melatonin made by a pharmacist, which was costly. Finding it here has been delightful; it gives me over 8 hours of restful sleep and enhances my well-being. I plan to try 3mg soon. Melatonin significantly improved my sleep and, consequently, my life quality.
Most Useful Review