Enzymes
9.5
Prevented heart problems
Most Useful Review
I learned about nattokinase after my father's heart attack. Since switching him to this natural supplement, he has not faced any further issues. His blood circulation has improved significantly, making this an essential supplement for those with heart disease.
9.5
Effective for heart disease
Most Useful Review
Nattokinase is a powerful enzyme that dissolves blood clots and has beneficial effects on heart disease. Widely studied in Asia and increasingly recognised by Western medicine, it supports a healthy cardiovascular system. I'm pleased with the product's quality and value.
Garlic
9.5
Cholesterol normalised
Most Useful Review
I took garlic extract to support my cardiovascular system after coronary stenting and a cerebral aneurysm. The results have been excellent; my cholesterol levels returned to normal within six months, despite long-term statin use. This supplement has benefitted not only me but also my family and friends.
9.5
Blood pressure improved
Most Useful Review
This fantastic tool has helped stop my gum bleeding, normalised my blood pressure, and reduced my cholesterol. I started taking two tablets daily for three months, along with Omega-3. My heart issues have resolved, and my dentist has noted significant gum health improvement.
Vitamin E
9.5
Heart disease protection
Most Useful Review
Wonderful! The strongest antioxidant, Vitamin E—400 IU daily—protects against heart disease. It improves blood circulation, supports protein synthesis, and is essential for reproductive health. I notice my skin becomes smoother while taking it and recommend following your doctor’s advice.
9.5
Heart disease support
Most Useful Review
Vitamin E is invaluable for heart disease prevention. It's a powerful antioxidant that purifies blood and improves circulation. I find it essential for skin health and use it with omega acids to maximise absorption.
Probiotics
4
Vitamin B12 deficiency and heart disease
Severe heart failure in a unique case of cobalamin-C-deficiency resolved with LVAD implantation and subsequent heart transplantation.
Most Relevant Research
We explored a unique case involving a young man diagnosed with Cobalamin C deficiency, a rare genetic condition affecting vitamin B12 metabolism. This condition can lead to serious health issues, including structural heart defects and severe heart failure.
Throughout his life, the patient received multiple treatments for his deficiency, including vitamin B12 supplements. However, he eventually developed severe heart failure due to dilated cardiomyopathy. Despite earlier improvements from medical treatments, his heart condition worsened, requiring advanced interventions such as a left ventricular assist device (LVAD) and ultimately a heart transplant.
Although vitamin B12 played a role in his overall treatment regime, the real focus was on managing his severe heart failure through these significant medical interventions. This case, unprecedented in its combination of LVAD implantation and heart transplant for someone with Cobalamin C deficiency, demonstrates that while vitamin B12 is essential, it is the advanced cardiac procedures that addressed the dire heart condition effectively.
In short, while vitamin B12 may improve symptoms of deficiency, advanced heart failure requires intensive medical strategies that go beyond vitamin supplementation alone.
Throughout his life, the patient received multiple treatments for his deficiency, including vitamin B12 supplements. However, he eventually developed severe heart failure due to dilated cardiomyopathy. Despite earlier improvements from medical treatments, his heart condition worsened, requiring advanced interventions such as a left ventricular assist device (LVAD) and ultimately a heart transplant.
Although vitamin B12 played a role in his overall treatment regime, the real focus was on managing his severe heart failure through these significant medical interventions. This case, unprecedented in its combination of LVAD implantation and heart transplant for someone with Cobalamin C deficiency, demonstrates that while vitamin B12 is essential, it is the advanced cardiac procedures that addressed the dire heart condition effectively.
In short, while vitamin B12 may improve symptoms of deficiency, advanced heart failure requires intensive medical strategies that go beyond vitamin supplementation alone.
9.5
Effective remedy
Most Useful Review
Definitely an effective remedy! I feel a surge of strength and energy. I've been ordering my favourite CoQ10 for years to support my heart and I'm very satisfied. For the best effect, you need to take it in courses. I highly recommend it to everyone!
Herbal Extracts
9.5
Improved heart health
Most Useful Review
Great remedy! I purchased a large pack for my family. My severe headaches and tinnitus, caused by spinal issues, vanished by the fifth day. Over the month, my condition greatly improved, and my blood pressure normalised. I now wake easily. My dad had reliable knee pain despite taking painkillers, and he felt relief using this. I wholeheartedly recommend it.
9.5
Enhances heart health
Most Useful Review
Ginkgo Biloba combined with ginseng activates cerebral circulation and improves mental performance, helping with heart disease. It restores energy, stabilises emotions, and is beneficial for people with diabetes. The product aids blood vessel health and reduces atherosclerotic progression.
Magnesium
8.8
Stabilised heart
Most Useful Review
I consider these capsules essential for managing my atrial fibrillation because I need magnesium. Having taken this complex for two years, I've noticed my heart works more steadily and no longer goes out of rhythm with the slightest excitement. The capsules are small and easy to take, although my wife prefers to empty the powder into her food. The packaging confirms this is acceptable. I highly recommend this product!
9.5
Aids heart recovery
Most Useful Review
Quality magnesium for recovery after intense workouts. It has notably improved my heart health, especially post-leg workouts. I recommend taking it with food, ideally in the evening, and consider adding zinc and BCAA for optimal results.
Polygonum Cuspidatum Complex
9.5
Boosts heart vitality
Most Useful Review
Resveratrol has been a game-changer for me in handling my Lyme disease. After 14 months on antibiotics, I gained energy and could increase my exercise from one to four miles. The research supports its anti-cancer properties, and it helps my heart health, so I’m continuing daily use.
9.5
Neuroprotective qualities
Most Useful Review
As an antioxidant, resveratrol combats free radicals and possesses anti-inflammatory effects. It may help slow cognitive decline and has potential benefits for heart disease by improving cerebral blood flow. Safe for adults, but pregnant or lactating women should consult their doctor before use.
Quercetin
9.5
Natural antihistamine
Most Useful Review
Having suffered from allergies and asthma for years, I turned to natural solutions like quercetin. This supplement reduces my allergic reactions and systemic inflammation, helping mitigate symptoms associated with heart disease.
9.5
Temperature normalised
Most Useful Review
Quercetin remarkably helped me return my unexplained fever to normal, which persisted for a year despite concerns about my heart disease. I initially began it upon my doctor’s suggestion and found it effective after switching to a higher dose.
9
Effective heart support
Most Useful Review
I previously purchased this supplement in gelatin capsules. I take it for my heart health and appreciate its effects. I tried increasing the dosage, but it made my heartbeat a bit restless. I'm grateful to IHERB and fellow reviewers for assisting me in choosing the right supplements, as doctors aren't always reliable.
9.5
Heart feels great
Most Useful Review
This supplement is of excellent quality, and the dosage is just right. It doesn't raise my cholesterol, and my heart feels fantastic. It even has a pleasant aroma.
Ubiquinol
9.5
Improves heart health
Most Useful Review
Ubiquinol has been a game-changer for me. I take it every morning with omega, and it has noticeably improved my strength, energy, and memory. With my heart condition and thyroid removal, I previously relied on other medications, but Ubiquinol has eliminated that need and has helped normalise my blood pressure.
9.5
Alleviates fatigue
Most Useful Review
Ubiquinol provides energy, combats fatigue, and supports heart health. I take it for insulin resistance-related tiredness, and it revives my energy and daily performance. It’s crucial for maintaining optimal health, especially as levels decrease with age.
Cacao
9.5
Aids heart function
Most Useful Review
This raw, organic cocoa is superb! I find it essential, especially as I deal with iron deficiency and stress. The magnesium it provides calms me, and it’s packed with antioxidants, so I’m supporting my heart health. After enjoying a cup, I feel uplifted due to the beneficial compounds it contains. I love its flavour and the fact that it’s not roasted, so all nutrients remain intact. I thoroughly recommend this brand for those wanting a health boost and a delicious drink.
9.5
Mood stabilisation
Most Useful Review
Regular daily intake of organic cocoa helps normalise sleep. It’s an antioxidant that supports the cardiovascular system, enhances circulation, reduces blood viscosity and regulates blood pressure, thus benefiting heart health.
Flax Seed Oil
9.5
Lowering cholesterol
Most Useful Review
This flax oil has significantly improved my heart health by lowering cholesterol and inflammation due to its omega content. As a vegan, I appreciate not needing to take fish oil or endure a fishy aftertaste. It's beneficial for all ages!
9.5
Doctor advice
Most Useful Review
Recommended by my physician, I began taking flaxseed oil to improve the elasticity of my blood vessels and to aid in detoxification. My entire family ordered it to support heart disease.
Potassium
7.5
Metabolism support
Most Useful Review
This potassium citrate maintains necessary potassium levels inside and outside cells. It is crucial for regulating bodily functions, including heart rhythm and metabolic processes. I take two capsules daily and recommend it.
10
Boosts heart health
Most Useful Review
This potassium citrate has been excellent for my heart issues and fatigue stemming from past stomach cancer. Recommended by my doctor, potassium greatly improved my energy and heart condition. I prefer capsules over powder, and combined with omega-3 and vitamin D3, it has been a miracle for my wellbeing.
L Carnitine
8.8
Supports heart function
Most Useful Review
For a long life and a healthy heart, L-carnitine is a natural substance related to B vitamins. It is vital for transporting fat tissue into muscle mitochondria, where aerobic exercise converts it into energy. Unlike a true vitamin, the body synthesises L-carnitine from amino acids, vitamins, and minerals. It prevents deficiencies particularly in vegetarians. L-carnitine serves as an antioxidant and vasodilator, enhancing blood flow to the heart and muscles. Studies highlight its benefits in treating conditions like angina, heart failure, and lower cholesterol. Notably, Dr. Sinatra recommends certain dosages based on individual conditions, emphasising its importance for heart disease treatment.
8.8
Helps heart issues
Most Useful Review
Dr Sinatra recommends this product as the best form of carnitine for Myalgic Encephalomyelitis, and it has notably benefitted my heart problems. My ability to remain upright improved drastically from just 10 minutes to about 20. Additionally, combining it with ubiquinol has given me further strength. Dr Sinatra calls these two, along with ribose and magnesium, the 'awesome foursome' for cardiac health.
Vitamin B Complex
9.5
Improves vitality
Most Useful Review
This vitamin complex has been a game-changer for me. After taking it for two months, I feel invigorated and energetic, better managing fatigue and stress. I only need one capsule daily, as it digests well. It's certainly the most effective vitamin B complex I've tried, helping me feel more balanced and enhancing my mood. I will continue to purchase this.
9.5
Improved heart health
Most Useful Review
EXCELLENT COMPLEX OF VITAMINS OF GROUP B. After the corona, I experienced heart issues, fatigue, hair loss, and low energy. At 47, I began taking a B complex and felt invigorated. My eyesight slightly improved, and my heart symptoms diminished. This complex contains essential B vitamins, which I believe are vital for treating heart disease.
Citrus Bergamotcitrus Bergamia
10
Clear arteries
Most Useful Review
I purchased this product along with NSK-SD (2,000 FU) and took one capsule of each daily. After 90 days, a test at the heart hospital revealed that my previously 25% blockage was now clear. At 77 years old, having undergone five bypasses two years prior to discovering this blockage, I am pleased to continue taking both products.
8.8
Great quality
Most Useful Review
I highly recommend Jarrow's Citrus Bergamot for heart and overall health. It is excellent quality and value. After experiencing a major heart issue recently, I use this for heart health and find it works best compared to other brands, which often lack the same quality control.
Vitamin K2
9.3
Reduces heart disease risk
Most Useful Review
I recommend a daily dose of 180 mcg of vitamin K2 (MK-7) for postmenopausal women and older men. It helps in calcium absorption, reduces coronary artery calcification, and overall mortality linked to heart disease. Statin users should consider K2 supplements, as statins lower vitamin K levels.
9.5
Supports calcium regulation
Most Useful Review
Vitamin K2 is key for proper calcium absorption, directing it to bones instead of arteries, thus helping prevent heart disease.
Vitamin Bs
9
Inositol counters lithium heart damage
Oral supplementation of inositols effectively recovered lithium-induced cardiac dysfunctions in mice.
Most Relevant Research
Our study aimed to understand how inositol supplementation could help combat heart issues caused by lithium in mice. We examined four groups of C57BL6 mice, some of which received lithium for eight weeks, while others either received inositol during or after the lithium treatment. We specifically looked at various heart functions, structures, and how the heart cells responded to stress.
We found that inositol has a significant protective effect on the heart. Mice that received inositol, either during or after lithium exposure, showed improvements in heart size, function, and electrical stability. For example, the inositol group had reduced heart cell swelling and better performance during stress tests. Overall, these findings suggest that inositol could serve as a beneficial strategy for managing lithium-induced cardiac issues.
Furthermore, the inositol treatment appeared to reverse changes associated with heart muscle enlargement and helped stabilize the expression of certain proteins critical for heart function. In contrast, untreated mice displayed increased cardiac dysfunction and other organ issues. Overall, the study underscores inositol's promise as a potential treatment for heart-related side effects arising from lithium use.
We found that inositol has a significant protective effect on the heart. Mice that received inositol, either during or after lithium exposure, showed improvements in heart size, function, and electrical stability. For example, the inositol group had reduced heart cell swelling and better performance during stress tests. Overall, these findings suggest that inositol could serve as a beneficial strategy for managing lithium-induced cardiac issues.
Furthermore, the inositol treatment appeared to reverse changes associated with heart muscle enlargement and helped stabilize the expression of certain proteins critical for heart function. In contrast, untreated mice displayed increased cardiac dysfunction and other organ issues. Overall, the study underscores inositol's promise as a potential treatment for heart-related side effects arising from lithium use.
8.8
Improved sleep quality
Most Useful Review
If you're tired and struggling with sleep, you may have a deficiency in vitamin B1. I've noticed that after starting thiamine, my sleep improved and I became less irritable. I'm convinced it positively affects heart disease as well.
Folate
8
Folate may reduce heart defect risks
Maternal multivitamin supplementation mitigates the risk of fetal congenital heart disease associated with high indoor total volatile organic compounds exposure in east china: a case-control study.
Most Relevant Research
In our exploration of the connection between heart health and maternal nutrition, we focused on the role of folate and multivitamin supplements during pregnancy. We investigated how these supplements might help combat the risks posed by total volatile organic compounds (TVOCs)—harmful indoor air pollutants—on developing babies.
We conducted a case-control study involving pregnant women at different stages of gestation, gathering data on their supplement intake, measuring important nutrients in their blood, and assessing their exposure to indoor air pollutants. Our analysis revealed a concerning link between high indoor TVOC levels and increased rates of congenital heart disease (CHD) in newborns.
Excitingly, we found that regular intake of multivitamins, including folate, could help alleviate these risks. This suggests that ensuring proper nutrient intake could be a simple yet effective strategy for expectant mothers living in environments with high indoor pollution levels. Overall, our findings underline the potential protective benefits of folate and a well-balanced diet in promoting heart health for the next generation.
We conducted a case-control study involving pregnant women at different stages of gestation, gathering data on their supplement intake, measuring important nutrients in their blood, and assessing their exposure to indoor air pollutants. Our analysis revealed a concerning link between high indoor TVOC levels and increased rates of congenital heart disease (CHD) in newborns.
Excitingly, we found that regular intake of multivitamins, including folate, could help alleviate these risks. This suggests that ensuring proper nutrient intake could be a simple yet effective strategy for expectant mothers living in environments with high indoor pollution levels. Overall, our findings underline the potential protective benefits of folate and a well-balanced diet in promoting heart health for the next generation.
9.5
Reduces homocysteine levels
Most Useful Review
Fully active folate helped lower my homocysteine level from 10 to 7, which is crucial for reducing heart disease risk. My mother’s level was 15, and now she takes folate with me. If you found this helpful, please like!
Protein
9
Nutrition Support Boosts Heart Health
Individualized Nutritional Support Improves Cardiac Function and Nutritional Status of Elderly Heart Failure Patients.
Most Relevant Research
We examined how individualized nutritional support impacts the heart health of elderly patients dealing with chronic heart failure (CHF). In our study involving 102 hospitalized CHF patients, we split participants into two groups—one receiving standard care and the other benefiting from customized nutritional guidance from a specialized nursing team.
Throughout the study, we closely monitored various health indicators, such as albumin, hemoglobin, and protein levels, as well as key measures of heart function. Our findings showed that both groups experienced improvements, but those receiving personalized nutrition demonstrated significantly better outcomes. Notably, their heart function improved, with a greater increase in left ventricular ejection fraction and a reduction in heart size markers compared to the control group.
Additionally, patients who received specialized nutritional support had lower levels of inflammatory markers and reported a higher quality of life. We observed that these participants were more satisfied with their nursing care. This evidence suggests that well-structured nutritional support, particularly focusing on protein intake and dietary factors, can play a crucial role in enhancing the health and well-being of patients with heart failure.
Throughout the study, we closely monitored various health indicators, such as albumin, hemoglobin, and protein levels, as well as key measures of heart function. Our findings showed that both groups experienced improvements, but those receiving personalized nutrition demonstrated significantly better outcomes. Notably, their heart function improved, with a greater increase in left ventricular ejection fraction and a reduction in heart size markers compared to the control group.
Additionally, patients who received specialized nutritional support had lower levels of inflammatory markers and reported a higher quality of life. We observed that these participants were more satisfied with their nursing care. This evidence suggests that well-structured nutritional support, particularly focusing on protein intake and dietary factors, can play a crucial role in enhancing the health and well-being of patients with heart failure.
9
Bone and skin health
Most Useful Review
Pumpkin seeds are fantastic! They enhance bone health and assist with heart disease due to their healthy fats and magnesium. I soak them overnight for better consumption.
Multivitamins
9.5
Health benefits noted
Most Useful Review
This Super Omega is excellent. It offers a great price, taste, and quality. I've noticed significant improvements in my hair and overall health, including inflammation reduction. The product contains many beneficial substances and is conveniently packaged. Its natural ingredients provide substantial health benefits. I highly recommend it to everyone; it meets all expectations and descriptions well.
9.5
Immune system support
Most Useful Review
This odourless Omega from iHerb has been easy to take. It's beneficial for children and adults alike, supporting heart health and immune function, especially during mental stress. I found it helpful while breastfeeding, and I've noticed excellent results for my nails, hair, and skin. Highly recommended!
Astragalus Root
9.5
Improved immunity
Most Useful Review
Excellent! I've taken Astragalus extract with my 86-year-old mother. We've noticed enhanced immune strength and no illnesses during this period. My mother's blood pressure remained stable, which I believe is due to this dietary supplement. We're currently on a break but will definitely reorder next month for prevention. The capsules are small and easy to take!
9.5
Quick recovery
Most Useful Review
I care deeply for him. It cures the flu and colds, particularly for lung diseases, allowing for quick recovery.
Coconut Oil
9.5
Multiple benefits
Most Useful Review
This coconut oil is superb for hair and skin, and I use it for cooking as well. It's one of the best oils I’ve tried for various applications including hair masks and skincare.
7.5
Excellent value supplement
Most Useful Review
Jarrow Formulas Extra Virgin Coconut Oil is a fantastic supplement for incorporating coconut oil's benefits into my diet. Each softgel contains 1,000 mg of high-quality oil, supporting heart disease and metabolism without an unpleasant aftertaste. I've noticed improved skin hydration and energy levels since including them in my routine.
Zinc
9
Zinc's role in cardiac protection
ANP Increases Zn Accumulation During Reperfusion in Ex Vivo and In Vivo Hearts.
Most Relevant Research
We explored the fascinating relationship between heart health, atrial natriuretic peptide (ANP), and zinc (Zn) in the context of ischemia/reperfusion (I/R) injury, a condition that occurs when blood supply returns to the heart after a period of being blocked. Our research utilized a range of models, including isolated heart experiments in rats and ANP knockout mice, along with clinical investigations involving plasma samples from 216 patients suffering from ischemia-related diseases.
During our experiments, we observed that levels of ANP significantly increased during reperfusion, which, in turn, promoted zinc accumulation in the heart tissue. This uptick in zinc led to protective effects on the heart, primarily by reducing injury during the reperfusion phase. Interestingly, when we applied a zinc chelator, we found that it negated the beneficial impacts of both ANP and zinc, highlighting the crucial role zinc plays in conjunction with ANP.
Furthermore, we discovered that ANP modulates zinc levels by downregulating a specific transporter known as ZnT8 through a pathway called PI3K signaling. While the interplay between ANP and zinc is evident, the study suggests that zinc alone's effectiveness in treating heart conditions cannot be fully isolated due to these combined effects. Overall, our findings point to a complex relationship in heart protection strategies, where both ANP and zinc play essential, interlinked roles.
During our experiments, we observed that levels of ANP significantly increased during reperfusion, which, in turn, promoted zinc accumulation in the heart tissue. This uptick in zinc led to protective effects on the heart, primarily by reducing injury during the reperfusion phase. Interestingly, when we applied a zinc chelator, we found that it negated the beneficial impacts of both ANP and zinc, highlighting the crucial role zinc plays in conjunction with ANP.
Furthermore, we discovered that ANP modulates zinc levels by downregulating a specific transporter known as ZnT8 through a pathway called PI3K signaling. While the interplay between ANP and zinc is evident, the study suggests that zinc alone's effectiveness in treating heart conditions cannot be fully isolated due to these combined effects. Overall, our findings point to a complex relationship in heart protection strategies, where both ANP and zinc play essential, interlinked roles.
9.5
Blood pressure improvement
Most Useful Review
Excellent! This is the best vitamin I have found. After taking it for a week, my blood pressure improved dramatically and my heart rate began to normalise.
Calcium
7
Calcium's role in stenting assessed
A Revised Optical Coherence Tomography-Derived Calcium Score to Predict Stent Underexpansion in Severely Calcified Lesions.
Most Relevant Research
We explored how severe calcium buildup in arteries may affect the success of heart stenting procedures, specifically focusing on identifying which calcified lesions might risk underexpansion of stents. In a study of 250 cases where optical coherence tomography (OCT) helped guide stenting, only those not treated with specific preparation methods were included.
The key findings showed that a significant portion—about 20%—of the lesions displayed stent underexpansion. We also discovered that certain features of the calcium, such as an angle over 270 degrees and a substantial thickness, were connected to reduced stent expansion.
Although the study emphasized calcium's role in predicting stent outcomes, we noted that it didn’t isolate how calcium management impacts heart disease directly. Thus, while the revised calcium scoring system can be useful in assessing stent expansion risk, the benefits of calcium treatment on heart disease remain less clear.
The key findings showed that a significant portion—about 20%—of the lesions displayed stent underexpansion. We also discovered that certain features of the calcium, such as an angle over 270 degrees and a substantial thickness, were connected to reduced stent expansion.
Although the study emphasized calcium's role in predicting stent outcomes, we noted that it didn’t isolate how calcium management impacts heart disease directly. Thus, while the revised calcium scoring system can be useful in assessing stent expansion risk, the benefits of calcium treatment on heart disease remain less clear.
9.5
Reduced cramps
Most Useful Review
This complex is among the best calcium preparations due to its chelated form, ensuring maximum absorption. Calcium strengthens bones, magnesium aids its distribution, and zinc supports collagen production. After using this for my parents, my father's arm cramps post-heart attack ceased, and my mother no longer suffers from leg cramps at night. Remember to take Vitamin D for better calcium absorption.
Selenium
8.8
Prevents heart disease
Most Useful Review
Selenium is a potent antioxidant that protects cells from free radicals. Excessive free radical formation due to smoking, alcohol, and stress leads to oxidative stress, damaging healthy cells and contributing to cardiovascular diseases. Studies indicate that a 50% increase in selenium levels in the blood correlates with a 24% reduction in coronary artery disease risk. It's also an anticarcinogen, proving effective against lung and breast cancer, and is vital for normal thyroid gland function, where selenium is most concentrated, playing a key role in hormone metabolism.
8.8
Antitumor effect noted
Most Useful Review
Selenium supports the cardiovascular and endocrine systems, particularly in certain thyroid conditions. Its preventative antitumour effects are essential in today's ecological climate. Moreover, selenium promotes the beauty of hair, skin, and nails, and serves as a powerful antioxidant that safeguards our immune system, while also being important for vision.
Choline
9
Inositol counters lithium heart damage
Oral supplementation of inositols effectively recovered lithium-induced cardiac dysfunctions in mice.
Most Relevant Research
Our study aimed to understand how inositol supplementation could help combat heart issues caused by lithium in mice. We examined four groups of C57BL6 mice, some of which received lithium for eight weeks, while others either received inositol during or after the lithium treatment. We specifically looked at various heart functions, structures, and how the heart cells responded to stress.
We found that inositol has a significant protective effect on the heart. Mice that received inositol, either during or after lithium exposure, showed improvements in heart size, function, and electrical stability. For example, the inositol group had reduced heart cell swelling and better performance during stress tests. Overall, these findings suggest that inositol could serve as a beneficial strategy for managing lithium-induced cardiac issues.
Furthermore, the inositol treatment appeared to reverse changes associated with heart muscle enlargement and helped stabilize the expression of certain proteins critical for heart function. In contrast, untreated mice displayed increased cardiac dysfunction and other organ issues. Overall, the study underscores inositol's promise as a potential treatment for heart-related side effects arising from lithium use.
We found that inositol has a significant protective effect on the heart. Mice that received inositol, either during or after lithium exposure, showed improvements in heart size, function, and electrical stability. For example, the inositol group had reduced heart cell swelling and better performance during stress tests. Overall, these findings suggest that inositol could serve as a beneficial strategy for managing lithium-induced cardiac issues.
Furthermore, the inositol treatment appeared to reverse changes associated with heart muscle enlargement and helped stabilize the expression of certain proteins critical for heart function. In contrast, untreated mice displayed increased cardiac dysfunction and other organ issues. Overall, the study underscores inositol's promise as a potential treatment for heart-related side effects arising from lithium use.
9.5
Lower cholesterol
Most Useful Review
Choline is essential for liver cell restoration and its protection, as well as preventing cardiovascular disease by lowering cholesterol levels. It maintains healthy blood vessels, strengthens the heart muscle, and normalises heart rate. Choline promotes regeneration of damaged liver cells and decreases gallstone formation. Insufficient choline intake leads to fat accumulation in the liver, resulting in fatty liver degeneration or hepatosis.
Cranberry
9.5
No more relapses
Most Useful Review
This drug is amazing! Throughout the spring and autumn when chronic kidney diseases flare up, we take this course and have not experienced any relapses for three years. We follow our doctor's recommendations.
8.8
Significant improvements
Most Useful Review
Excellent! Natural remedy. I first acquired this remedy as I had tried many treatments for chronic cystitis. The product appealed to me with its composition—concentrated cranberry extract, equivalent to a glass or two of cranberry juice. As fruit drink isn’t always available, capsules are a convenient option. To treat my condition, I took up to 4 capsules daily while ensuring I drank 2 litres of water. After a week of treatment, I noticed significant improvements. I believe I can continue taking 1 capsule daily for prevention and to avoid any symptoms. The capsules are small and easy to swallow. I'm delighted with the product.
Elderberry
NOW Foods Elderberry
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 4 Reviews
8.5
8.8
Supports heart health
Most Useful Review
Elderberry is remarkable, as nearly all its parts have therapeutic uses. It enhances immunity, alleviates cold symptoms, and normalises digestion. Additionally, it helps with heart disease and reduces excess fluid in the body. Rich in vitamins A, B, and C, alongside beneficial minerals, it’s recommended for various ailments, including skin issues and depression. As an antioxidant, it detoxifies the body effectively.
8.8
Helpful for flu
Most Useful Review
This product is effective for colds and flu, as it boosts the immune system and combats inflammation. Elderberry's properties rival those of many prescription medications. However, I advise consulting a doctor before use. There’s a noticeable effect.
Tumeric
8
Curcumin shows promise for metabolic health
Impacts of Curcumin Supplementation on Cardiometabolic Risk Factors in Patients With Polycystic Ovary Syndrome: A Systematic Review and Dose-Response Meta-Analysis.
Most Relevant Research
We examined how curcumin, a key ingredient in turmeric, impacts cardiometabolic health in women with polycystic ovary syndrome (PCOS), a condition often linked to heart disease risks. In our systematic review, we analyzed data from eight randomized clinical trials to understand if curcumin could be beneficial for controlling various metabolic factors.
Our findings suggest that curcumin supplementation can lead to significant reductions in fasting blood sugar levels, insulin resistance, and total cholesterol among women suffering from PCOS. Specifically, we noticed substantial improvements in markers like the homeostasis model assessment of insulin resistance and the quantitative insulin sensitivity check index, which are crucial for heart health.
However, it’s important to highlight that while curcumin shows promise in addressing these metabolic issues, it did not significantly impact body mass index or other hormonal levels related to heart disease risk. Thus, while curcumin supplementation might improve certain metabolic factors, its direct effects on heart disease require further exploration.
Our findings suggest that curcumin supplementation can lead to significant reductions in fasting blood sugar levels, insulin resistance, and total cholesterol among women suffering from PCOS. Specifically, we noticed substantial improvements in markers like the homeostasis model assessment of insulin resistance and the quantitative insulin sensitivity check index, which are crucial for heart health.
However, it’s important to highlight that while curcumin shows promise in addressing these metabolic issues, it did not significantly impact body mass index or other hormonal levels related to heart disease risk. Thus, while curcumin supplementation might improve certain metabolic factors, its direct effects on heart disease require further exploration.
9.5
Eliminated pain relief
Most Useful Review
This is a fantastic product. I use it for its anti-inflammatory properties, which have allowed me to nearly stop using Ibuprofen. My cardiologist considers me his most boring patient after having two heart stents for almost six years. I also take nattokinase and serrapeptase to maintain excellent cardiovascular health.
Oleuropein
9.5
Breath recovery
Most Useful Review
Thanks to this product, my father has recovered his breath and can walk without becoming out of breath. I'm thrilled with the results, which have even persisted after stopping the supplement. Olive leaf is excellent for preventing heart disease, and I highly recommend it.
8.8
Energy boost
Most Useful Review
I've found these olive leaf capsules from Nature's Way to be a revelation. Since starting them a few months ago, I feel more energetic and my overall health has improved. The capsules are easy to swallow, well absorbed, and known for their antioxidant properties, particularly in supporting heart disease and vascular health.
L Lysine
9
Immune system boost
Most Useful Review
It effectively boosts immunity, collagen, and heart health. I mix it with L-Arginine to promote relaxation and overall well-being.
8.8
Heart health support
Most Useful Review
I take one tablet three times daily, increasing to two or three capsules during herpes outbreaks. Lysine works best on an empty stomach as it helps with collagen formation, anxiety, and immune support. Research shows it prevents herpes recurrences and speeds up healing, making it beneficial for overall health, including heart health.
Vitamin B6
9
Vitamin B6 shows heart health promise
Protective effects of pyridoxine, amlodipine, and their combination in a vasopressin-induced angina model in rats.
Most Relevant Research
We explored the effects of vitamin B6 (pyridoxine) on heart health, specifically looking at its protective qualities against angina provoked by vasopressin in a rat model. Vasopressin was administered to observe its impact on heart function, which included elevated stress on the heart indicated by changes on the electrocardiogram and increased cardiac enzymes.
The study found that when we gave rats pyridoxine in varying doses, it effectively reduced the ST elevation and heart rate changes caused by vasopressin. Notably, higher doses of pyridoxine (7 mg/kg) showed significant protective effects, outperforming both amlodipine and isosorbide. In addition, we observed that pyridoxine at these doses helped prevent cardiac tissue damage and improved heart structure.
Interestingly, while combining pyridoxine with amlodipine led to a trend of increased adverse cardiovascular events, the results underscored the potential of vitamin B6 in enhancing heart health. It appears vitamin B6 may work by improving certain functions in the body that support heart health, such as better blood vessel function and reduced levels of harmful substances.
Overall, our findings suggest that vitamin B6 could serve as a promising agent in preventing coronary heart disease, but more research is necessary to fully explore its benefits and practical applications in humans.
The study found that when we gave rats pyridoxine in varying doses, it effectively reduced the ST elevation and heart rate changes caused by vasopressin. Notably, higher doses of pyridoxine (7 mg/kg) showed significant protective effects, outperforming both amlodipine and isosorbide. In addition, we observed that pyridoxine at these doses helped prevent cardiac tissue damage and improved heart structure.
Interestingly, while combining pyridoxine with amlodipine led to a trend of increased adverse cardiovascular events, the results underscored the potential of vitamin B6 in enhancing heart health. It appears vitamin B6 may work by improving certain functions in the body that support heart health, such as better blood vessel function and reduced levels of harmful substances.
Overall, our findings suggest that vitamin B6 could serve as a promising agent in preventing coronary heart disease, but more research is necessary to fully explore its benefits and practical applications in humans.
9.5
Heart health improvements
Most Useful Review
Finding this supplement was a revelation; it combines active folic acid and B12 in a sublingual form, helping absorption and potentially lowering heart disease risks. I noticed a lift in mood and energy shortly after taking it. The slight chemical sweet taste is the only downside for me.
Coenzyme Q10
9
CoQ10 shows heart health promise
Beneficial Antioxidant Effects of Coenzyme Q10 in In Vitro and In Vivo Models of CDKL5 Deficiency Disorder.
Most Relevant Research
We aimed to investigate the effects of Coenzyme Q10 (CoQ10) on heart health in the context of CDKL5 deficiency disorder (CDD). CDD is a complex condition caused by mutations in the CDKL5 gene, leading to severe developmental challenges and systemic issues, including oxidative stress.
Our study demonstrated that CoQ10 supplementation can significantly reduce harmful levels of reactive oxygen species (ROS) and help restore a balanced state of glutathione in the body. This is important because oxidative stress is believed to contribute to various health problems, including those affecting the heart.
Additionally, we found that CoQ10 not only improved markers of cellular health and proliferation in a human neuron model but also provided protective effects against lipid peroxidation and DNA damage in the hearts of a mouse model of CDD.
Overall, our findings suggest that CoQ10 may play a crucial role in alleviating oxidative stress and protecting heart health in individuals with CDD, offering a potential therapeutic avenue worth exploring further.
Our study demonstrated that CoQ10 supplementation can significantly reduce harmful levels of reactive oxygen species (ROS) and help restore a balanced state of glutathione in the body. This is important because oxidative stress is believed to contribute to various health problems, including those affecting the heart.
Additionally, we found that CoQ10 not only improved markers of cellular health and proliferation in a human neuron model but also provided protective effects against lipid peroxidation and DNA damage in the hearts of a mouse model of CDD.
Overall, our findings suggest that CoQ10 may play a crucial role in alleviating oxidative stress and protecting heart health in individuals with CDD, offering a potential therapeutic avenue worth exploring further.
9.5
Supports heart health
Most Useful Review
This product works excellently! Coenzyme Q10 is vital for heart health and energy production, also acting as a powerful immunomodulator. It can even help slow down aging. I suggest combining it with Omega 3 for better results. Just be cautious as it may lower blood pressure. I've ordered numerous supplements from iHerb, and I believe they can aid in maintaining our health.
Taurine
8
Taurine shows potential for heart health
Insights into the cardiovascular benefits of taurine: a systematic review and meta-analysis.
Most Relevant Research
We examined the effects of taurine on heart disease through a systematic review of randomized controlled trials. By analyzing data from various studies, we assessed how taurine influences key cardiovascular metrics like heart rate and blood pressure.
While the results indicated that taurine could help prevent hypertension and improve cardiac function, the findings were not universally consistent. Thus, incorporating taurine might be beneficial for those at risk of heart disease, but further research is essential for conclusive recommendations.
While the results indicated that taurine could help prevent hypertension and improve cardiac function, the findings were not universally consistent. Thus, incorporating taurine might be beneficial for those at risk of heart disease, but further research is essential for conclusive recommendations.
9.5
Heart function support
Most Useful Review
The most important amino acid in the body! Taurine is essential for many bodily functions, including the elimination of toxins. It lowers blood pressure, reduces nervous excitability, decreases blood glucose levels, and supports heart health. I recommend a daily dose of 500 to 2000 mg, taken in courses with breaks.
Red Yeast Rice
9
CoQ10 shows heart health promise
Beneficial Antioxidant Effects of Coenzyme Q10 in In Vitro and In Vivo Models of CDKL5 Deficiency Disorder.
Most Relevant Research
We aimed to investigate the effects of Coenzyme Q10 (CoQ10) on heart health in the context of CDKL5 deficiency disorder (CDD). CDD is a complex condition caused by mutations in the CDKL5 gene, leading to severe developmental challenges and systemic issues, including oxidative stress.
Our study demonstrated that CoQ10 supplementation can significantly reduce harmful levels of reactive oxygen species (ROS) and help restore a balanced state of glutathione in the body. This is important because oxidative stress is believed to contribute to various health problems, including those affecting the heart.
Additionally, we found that CoQ10 not only improved markers of cellular health and proliferation in a human neuron model but also provided protective effects against lipid peroxidation and DNA damage in the hearts of a mouse model of CDD.
Overall, our findings suggest that CoQ10 may play a crucial role in alleviating oxidative stress and protecting heart health in individuals with CDD, offering a potential therapeutic avenue worth exploring further.
Our study demonstrated that CoQ10 supplementation can significantly reduce harmful levels of reactive oxygen species (ROS) and help restore a balanced state of glutathione in the body. This is important because oxidative stress is believed to contribute to various health problems, including those affecting the heart.
Additionally, we found that CoQ10 not only improved markers of cellular health and proliferation in a human neuron model but also provided protective effects against lipid peroxidation and DNA damage in the hearts of a mouse model of CDD.
Overall, our findings suggest that CoQ10 may play a crucial role in alleviating oxidative stress and protecting heart health in individuals with CDD, offering a potential therapeutic avenue worth exploring further.
9.5
Cholesterol lowering
Most Useful Review
Red yeast rice with CoQ10 is an excellent health supplement. It can reduce cholesterol and triglycerides while enhancing heart function. Studies indicate that consuming 2.4 grams daily can effectively lower cholesterol. However, it’s important to consult a physician if you have liver or kidney issues.
Chromium
8.8
Lowers cholesterol
Most Useful Review
Cinnamon Sabri is essential during menopause for various reasons: it helps manage blood sugar levels, lowers cholesterol, and has antibacterial properties. The cinnamon in it promotes insulin secretion, aiding in diabetes prevention and improving heart disease risk. Additionally, it supports digestion and promotes circulation. However, it should only be taken as a supplement and not in excess, as high doses may cause side effects like diarrhoea and nausea.
7.5
Promotes heart health
Most Useful Review
This blend of cinnamon and chromium supports stable blood sugar levels and metabolic health. Together, they enhance insulin sensitivity and support cardiovascular health, which is crucial in preventing heart disease. I appreciate the benefits of this supplement in maintaining my overall well-being.
Antioxidant Apple
4
Probiotics enhance cholesterol management
Probiotics combined with atorvastatin administration in the treatment of hyperlipidemia: A randomized, double-blind, placebo-controlled clinical trial.
Most Relevant Research
In a study exploring how probiotics impact heart health, we examined thirty-three patients with high cholesterol levels. They were randomly split into two groups: one received probiotics along with atorvastatin, while the other received a placebo with atorvastatin.
After three months, results showed that the probiotic group had a higher diversity of gut bacteria and improved cholesterol levels. It seems probiotics may help reshape gut microbiota, thus offering an additional approach for managing hyperlipidemia in heart disease patients.
After three months, results showed that the probiotic group had a higher diversity of gut bacteria and improved cholesterol levels. It seems probiotics may help reshape gut microbiota, thus offering an additional approach for managing hyperlipidemia in heart disease patients.
8.8
Reduced heart issues
Most Useful Review
After several months of taking resveratrol alongside magnesium, the tachycardia and pressure in my heart that had bothered me since my youth have nearly vanished. I did not take any medication during this time.
Evening Primrose
9.5
Heart disease management
Most Useful Review
I suffer from PCOS, which caused hair loss. After taking Primula, my hair stopped falling out. Despite a setback due to travel, I’ve reordered Borage Oil for its higher active substance concentration. Stress management is also key to recovery.
9.5
Supports reproductive health
Most Useful Review
This product is rich in valuable components and positively affects many bodily systems. Evening primrose oil aids tissue regeneration, improves heart function, and supports the reproductive system in both genders. Its numerous benefits are noteworthy.
L Theanine
9
Inositol counters lithium heart damage
Oral supplementation of inositols effectively recovered lithium-induced cardiac dysfunctions in mice.
Most Relevant Research
Our study aimed to understand how inositol supplementation could help combat heart issues caused by lithium in mice. We examined four groups of C57BL6 mice, some of which received lithium for eight weeks, while others either received inositol during or after the lithium treatment. We specifically looked at various heart functions, structures, and how the heart cells responded to stress.
We found that inositol has a significant protective effect on the heart. Mice that received inositol, either during or after lithium exposure, showed improvements in heart size, function, and electrical stability. For example, the inositol group had reduced heart cell swelling and better performance during stress tests. Overall, these findings suggest that inositol could serve as a beneficial strategy for managing lithium-induced cardiac issues.
Furthermore, the inositol treatment appeared to reverse changes associated with heart muscle enlargement and helped stabilize the expression of certain proteins critical for heart function. In contrast, untreated mice displayed increased cardiac dysfunction and other organ issues. Overall, the study underscores inositol's promise as a potential treatment for heart-related side effects arising from lithium use.
We found that inositol has a significant protective effect on the heart. Mice that received inositol, either during or after lithium exposure, showed improvements in heart size, function, and electrical stability. For example, the inositol group had reduced heart cell swelling and better performance during stress tests. Overall, these findings suggest that inositol could serve as a beneficial strategy for managing lithium-induced cardiac issues.
Furthermore, the inositol treatment appeared to reverse changes associated with heart muscle enlargement and helped stabilize the expression of certain proteins critical for heart function. In contrast, untreated mice displayed increased cardiac dysfunction and other organ issues. Overall, the study underscores inositol's promise as a potential treatment for heart-related side effects arising from lithium use.
9.5
Anxiety alleviation
Most Useful Review
L-theanine has greatly helped with my anxiety. Previously, my heart would race uncontrollably in stressful situations, but now I feel much calmer and can approach my day without that constant stress.
Vitamin C
7
Vitamin C boosts NK cell function
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
Most Relevant Research
We delved into how vitamin C, specifically ascorbic acid, influences the behavior of natural killer (NK) cells in patients with coronary artery disease (CAD). Our exploration involved isolating NK cells from 29 CAD patients and stimulating them with various factors, including vitamin C, to analyze their growth and proliferation. Notably, the results indicated that nearly all NK cells responded positively to vitamin C, showcasing a significant boost in their ability to proliferate. This suggests that vitamin C could play a role in enhancing the immune function of these cells, which is particularly important for those vulnerable to heart disease.
Moreover, we observed a correlation between the serum levels of lactate dehydrogenase (LDH) and NK cell activity. Specifically, higher LDH levels appeared to be linked to a decreased NK cell proliferation response when stimulated with interleukins, which are signaling molecules crucial for immune responses. This finding raises interesting questions about the role of LDH not just as a marker for cell damage, but potentially as an influencing factor in immune regulation.
In summary, our findings point to vitamin C's potential to enhance NK cell proliferation in CAD patients. Furthermore, the serum LDH levels could serve as a valuable indicator of NK cell function, suggesting a complex interplay between immune response and heart disease. Overall, these insights may open new avenues for integrating vitamin C into treatment regimens for improving immune health in heart disease.
Moreover, we observed a correlation between the serum levels of lactate dehydrogenase (LDH) and NK cell activity. Specifically, higher LDH levels appeared to be linked to a decreased NK cell proliferation response when stimulated with interleukins, which are signaling molecules crucial for immune responses. This finding raises interesting questions about the role of LDH not just as a marker for cell damage, but potentially as an influencing factor in immune regulation.
In summary, our findings point to vitamin C's potential to enhance NK cell proliferation in CAD patients. Furthermore, the serum LDH levels could serve as a valuable indicator of NK cell function, suggesting a complex interplay between immune response and heart disease. Overall, these insights may open new avenues for integrating vitamin C into treatment regimens for improving immune health in heart disease.
9.5
Boosts heart health
Most Useful Review
Excellent! This vitamin C is the best on iHerb. All vitamins from this brand include probiotics, which are especially beneficial for those aged 40-50. They are completely natural and 100% digestible. I immediately feel more energised and it protects against viruses. For collagen and heart disease, I take it daily with my husband. We have tried various vitamin C supplements, but we will only purchase this one from now on.
Docosahexaenoic Acid
8
Omega-3s may reduce coronary risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We explored the impact of omega-3 fatty acids, particularly docosahexaenoic acid (DHA), on heart disease via the large-scale VITAL study. This trial involved over 25,000 older adults in the U.S. who were monitored for about 5.3 years to assess how omega-3 FA supplementation influences cardiovascular events.
Although the findings from the VITAL trial indicated no significant results for major cardiovascular events, our analysis employing Bayesian methods suggested a different story. By incorporating previous research evidence, we found that daily supplementation of omega-3 fatty acids appears to significantly lower the risk of coronary events like heart attacks. However, it's important to note that this effect did not extend to reducing the risk of stroke.
Overall, this reevaluation supports the idea that omega-3 fatty acids, including DHA, could play a meaningful role in heart health, especially for preventing coronary-related issues. While the trial didn't show an impact on all aspects of heart disease, the results regarding coronary events provide valuable insights for the use of omega-3s in primary prevention strategies.
Although the findings from the VITAL trial indicated no significant results for major cardiovascular events, our analysis employing Bayesian methods suggested a different story. By incorporating previous research evidence, we found that daily supplementation of omega-3 fatty acids appears to significantly lower the risk of coronary events like heart attacks. However, it's important to note that this effect did not extend to reducing the risk of stroke.
Overall, this reevaluation supports the idea that omega-3 fatty acids, including DHA, could play a meaningful role in heart health, especially for preventing coronary-related issues. While the trial didn't show an impact on all aspects of heart disease, the results regarding coronary events provide valuable insights for the use of omega-3s in primary prevention strategies.
9.5
Organic heart support
Most Useful Review
I highly recommend Garden of Life, Oceans Mom, Strawberry DHA Prenatal for expectant mothers. It helps maintain heart and brain health during pregnancy. The strawberry flavour is enjoyable, and the capsules are easy to swallow with no unpleasant aftertaste. It's organic and free from artificial additives, making it a great choice.
Biopqq
Jarrow Formulas PQQ
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 11 Reviews
8.2
9.5
Excellent for heart
Most Useful Review
Excellent! This product significantly supports the heart and blood vessels.
7.5
Enhances cellular energy
Most Useful Review
Continuing with this product is beneficial. It supports cellular energy production, mitochondrial creation, and enhances brain function and memory. Taken over three months, I expect it to improve overall health, including immune cell efficiency, thereby aiding in self-healing, which is crucial for treating heart disease and other ailments.
Pqq
Jarrow Formulas PQQ
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 11 Reviews
8.2
9.5
Excellent for heart
Most Useful Review
Excellent! This product significantly supports the heart and blood vessels.
7.5
Enhances cellular energy
Most Useful Review
Continuing with this product is beneficial. It supports cellular energy production, mitochondrial creation, and enhances brain function and memory. Taken over three months, I expect it to improve overall health, including immune cell efficiency, thereby aiding in self-healing, which is crucial for treating heart disease and other ailments.
Fish Oil
9
Omega-3 lowers coronary risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We explored the impact of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on heart disease through a significant study known as the VITAL trial. This study involved nearly 26,000 older adults in the U.S. and aimed to determine the effects of daily EPA supplementation on cardiovascular events over an average follow-up of 5.3 years.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
8.8
Improved heart health
Most Useful Review
Quality product! This fish oil is excellent for health conscious individuals. It provides a good dose of fatty acids and comes from a reputable manufacturer. At 32, I take these capsules for my hair and skin. After various diets, fish oil has been a saviour: my skin is supple, and my hair is less damaged. My parents ordered it for heart disease; my mother, 55, noticed improvement in energy and skin condition. I recommend this product, taking 2 capsules 1-3 times daily with meals. The large capsules are easy to swallow.
Spirulina
8.3
Boosts heart health
Most Useful Review
Spirulina is a nutrient powerhouse with numerous benefits: it aids muscle recovery, lowers harmful cholesterol, and strengthens the immune system. It's particularly useful for those facing cancer and allergies. Additionally, it’s high in iron, which helps prevent heart disease, particularly for women and children.
8.5
Reduces heart disease
Most Useful Review
Excellent! Spirulina helps eliminate anaemia due to its high protein and iron content, reduces inflammation, and consequently lowers risks of heart disease. It boosts concentration, detoxifies the body, and improves liver function. Its benefits extend to preventing diseases and enhancing brain clarity, as well as protecting against radioactive pollution.
Vitamin D
4
Vitamin D impact on exercise capacity
Vitamin D levels correlate with exercise capacity in adults with CHD.
Most Relevant Research
We investigated the relationship between vitamin D levels and exercise capacity in adults with congenital heart disease (CHD). In our study, we examined 55 CHD patients and 55 healthy peers, looking at how their vitamin D levels correlated with various health metrics, including their ability to exercise.
Despite the common concern about vitamin D deficiency, we found that levels were similar between CHD patients and healthy controls, though both groups exhibited high rates of vitamin D insufficiency. While vitamin D levels didn't significantly correlate with many factors such as age, body mass index, or blood pressure, we did observe a noteworthy connection between vitamin D levels and exercise performance.
Specifically, lower vitamin D levels were linked to reduced exercise capacity among CHD patients. This suggests that while vitamin D may not drastically affect heart disease outcomes on its own, it plays a role in physical performance. The findings highlight the need for further research into whether supplementing vitamin D might enhance exercise capacity in individuals with vitamin D insufficiency and CHD.
Despite the common concern about vitamin D deficiency, we found that levels were similar between CHD patients and healthy controls, though both groups exhibited high rates of vitamin D insufficiency. While vitamin D levels didn't significantly correlate with many factors such as age, body mass index, or blood pressure, we did observe a noteworthy connection between vitamin D levels and exercise performance.
Specifically, lower vitamin D levels were linked to reduced exercise capacity among CHD patients. This suggests that while vitamin D may not drastically affect heart disease outcomes on its own, it plays a role in physical performance. The findings highlight the need for further research into whether supplementing vitamin D might enhance exercise capacity in individuals with vitamin D insufficiency and CHD.
9.5
Angina symptoms reduce
Most Useful Review
Heart throbbing and painful leg cramps have disappeared. After years of unexplained angina symptoms, this combination of minerals proved effective for me, essential for addressing heart disease.
Omega 3
9
Omega-3 lowers coronary risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We explored the impact of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on heart disease through a significant study known as the VITAL trial. This study involved nearly 26,000 older adults in the U.S. and aimed to determine the effects of daily EPA supplementation on cardiovascular events over an average follow-up of 5.3 years.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
9.5
Reduces cholesterol levels
Most Useful Review
I chose this fish oil for its ideal ratio of EPA to DHA (2:1). Omega-3 alleviates depression, enhances vision, and plays a crucial role in brain function while reducing risks of heart disease and cancer. The taste is pleasant, and it doesn't have an unpleasant smell. I can bite into the capsule without swallowing it. I’ve reordered this product several times!
Eicosapentaenoic Acid
9
Omega-3 lowers coronary risk
A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events.
Most Relevant Research
We explored the impact of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on heart disease through a significant study known as the VITAL trial. This study involved nearly 26,000 older adults in the U.S. and aimed to determine the effects of daily EPA supplementation on cardiovascular events over an average follow-up of 5.3 years.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.
This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
9.5
Improved immunity
Most Useful Review
I've been taking this supplement for over a month and noticed improved health, increased immunity, and fewer headaches. My skin is better in terms of elasticity and reduces wrinkles. The bonus small package is great for convenience.
Cod Liver Oil
9
DHA in cod liver oil benefits heart
Docosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway.
Most Relevant Research
We explored the effects of docosahexaenoic acid (DHA), a key component of cod liver oil, on heart health, especially after a heart attack. The study investigated whether DHA could play a role in protecting the heart from damage caused by myocardial infarction (MI).
Using both lab-based and animal models, we observed that DHA not only improved the survival of heart cells affected by low oxygen but also reduced overall heart area damage in mice after an MI. Remarkably, we found that DHA enhanced the body's natural process of autophagy, which helps clear out damaged cells and supports heart function.
With the inhibition of autophagy, we noted that the beneficial effects of DHA diminished, underscoring the importance of this process in heart protection. The study showed that DHA works through a specific signaling pathway, the AMPK/mTOR pathway, which is essential for autophagy and improved heart health.
Overall, our findings suggest that incorporating DHA, as found in cod liver oil, could be a promising strategy to support heart health after a heart attack and reduce long-term damage.
Using both lab-based and animal models, we observed that DHA not only improved the survival of heart cells affected by low oxygen but also reduced overall heart area damage in mice after an MI. Remarkably, we found that DHA enhanced the body's natural process of autophagy, which helps clear out damaged cells and supports heart function.
With the inhibition of autophagy, we noted that the beneficial effects of DHA diminished, underscoring the importance of this process in heart protection. The study showed that DHA works through a specific signaling pathway, the AMPK/mTOR pathway, which is essential for autophagy and improved heart health.
Overall, our findings suggest that incorporating DHA, as found in cod liver oil, could be a promising strategy to support heart health after a heart attack and reduce long-term damage.
9.5
Thyroid support
Most Useful Review
For thyroid health, vitamin A deficiency is linked to heart disease. Research shows that vitamin A can lower TSH levels and raise T3, the key thyroid hormone. Cod liver oil is a fantastic source of active vitamin A and omega-3 fatty acids EPA for heart health and DHA for brain function.
Vitamin D3
7
Vitamin D3's cardiomyoblast protection
Sirtuin 1 mediates the pro-survival effects of vitamin D in angiotensin II-induced hypertrophy of H9c2 cardiomyoblasts.
Most Relevant Research
We explored the effects of vitamin D3, a vital nutrient, on heart health, particularly in relation to a common risk factor known as angiotensin II. Our study focused on H9c2 cardiomyoblasts, a type of heart cell, to understand how vitamin D3 interacts with this condition.
By exposing these cells to angiotensin II along with vitamin D3, we aimed to see if the vitamin could shield the cells from damage. Interestingly, we found that vitamin D3 showed significant potential for preventing cell damage when SIRT1, a protein involved in cell survival, was present. However, when we blocked SIRT1, vitamin D3 wasn’t able to protect the heart cells effectively against the harmful effects induced by angiotensin II.
While vitamin D3 did help mitigate some effects of hypertrophy, or heart cell enlargement, it was clear that SIRT1 was crucial for the vitamin's protective benefits. This finding suggests that enhancing SIRT1 activity could be an exciting path forward for developing treatments to combat heart disease linked to hypertrophy and other conditions related to angiotensin II.
By exposing these cells to angiotensin II along with vitamin D3, we aimed to see if the vitamin could shield the cells from damage. Interestingly, we found that vitamin D3 showed significant potential for preventing cell damage when SIRT1, a protein involved in cell survival, was present. However, when we blocked SIRT1, vitamin D3 wasn’t able to protect the heart cells effectively against the harmful effects induced by angiotensin II.
While vitamin D3 did help mitigate some effects of hypertrophy, or heart cell enlargement, it was clear that SIRT1 was crucial for the vitamin's protective benefits. This finding suggests that enhancing SIRT1 activity could be an exciting path forward for developing treatments to combat heart disease linked to hypertrophy and other conditions related to angiotensin II.
9.5
Strong immunity support
Most Useful Review
One capsule a day ensures effective immunity against various viral diseases. My family, including my children, hasn't had a cold or any viral illness for years, aside from a mild runny nose that resolved quickly. With my thyroid condition, vitamin D3 is essential. Its deficiency is linked to heart disease and other autoimmune issues.
Vitamin A
7
Vitamin D3's cardiomyoblast protection
Sirtuin 1 mediates the pro-survival effects of vitamin D in angiotensin II-induced hypertrophy of H9c2 cardiomyoblasts.
Most Relevant Research
We explored the effects of vitamin D3, a vital nutrient, on heart health, particularly in relation to a common risk factor known as angiotensin II. Our study focused on H9c2 cardiomyoblasts, a type of heart cell, to understand how vitamin D3 interacts with this condition.
By exposing these cells to angiotensin II along with vitamin D3, we aimed to see if the vitamin could shield the cells from damage. Interestingly, we found that vitamin D3 showed significant potential for preventing cell damage when SIRT1, a protein involved in cell survival, was present. However, when we blocked SIRT1, vitamin D3 wasn’t able to protect the heart cells effectively against the harmful effects induced by angiotensin II.
While vitamin D3 did help mitigate some effects of hypertrophy, or heart cell enlargement, it was clear that SIRT1 was crucial for the vitamin's protective benefits. This finding suggests that enhancing SIRT1 activity could be an exciting path forward for developing treatments to combat heart disease linked to hypertrophy and other conditions related to angiotensin II.
By exposing these cells to angiotensin II along with vitamin D3, we aimed to see if the vitamin could shield the cells from damage. Interestingly, we found that vitamin D3 showed significant potential for preventing cell damage when SIRT1, a protein involved in cell survival, was present. However, when we blocked SIRT1, vitamin D3 wasn’t able to protect the heart cells effectively against the harmful effects induced by angiotensin II.
While vitamin D3 did help mitigate some effects of hypertrophy, or heart cell enlargement, it was clear that SIRT1 was crucial for the vitamin's protective benefits. This finding suggests that enhancing SIRT1 activity could be an exciting path forward for developing treatments to combat heart disease linked to hypertrophy and other conditions related to angiotensin II.
10
Supports immunity
Most Useful Review
Cod liver oil significantly benefits skin health and delays ageing. It supports heart health, memory, and reduces diabetes risk. Additionally, it boosts immunity against infections and aids in lowering triglycerides and cholesterol. It’s derived from cod liver, providing higher vitamins A and D than regular fish oils.
Iron
5
Iron deficiency worsens heart failure
Impact of iron deficiency on congestion and postdischarge survival in patients recently hospitalised for decompensated heart failure: a multicentre, prospective, observational analysis of the FERIC-RO study.
Most Relevant Research
We explored the impact of iron deficiency (ID) on patients hospitalized for worsening chronic heart failure. In a multicentre study with 163 patients, we found that iron deficiency was prevalent, affecting over half of those studied. This condition appeared to be linked to worse outcomes during hospital stays and beyond.
Patients with iron deficiency not only showed more congestion but also had higher levels of natriuretic peptides, which are markers related to heart failure. Interestingly, while mortality rates at 30 days post-discharge did not differ significantly between those with and without iron deficiency, there was a stark contrast at 90 days. The ID group experienced much higher mortality at this point, suggesting that iron deficiency might play a critical role in worsening long-term survival, even if initial outcomes didn't show immediate differences.
Overall, while we observed notable associations between iron deficiency and heart failure outcomes, the study did not specifically evaluate the effectiveness of iron treatments, limiting our ability to conclude direct benefits of iron supplementation on heart failure management.
Patients with iron deficiency not only showed more congestion but also had higher levels of natriuretic peptides, which are markers related to heart failure. Interestingly, while mortality rates at 30 days post-discharge did not differ significantly between those with and without iron deficiency, there was a stark contrast at 90 days. The ID group experienced much higher mortality at this point, suggesting that iron deficiency might play a critical role in worsening long-term survival, even if initial outcomes didn't show immediate differences.
Overall, while we observed notable associations between iron deficiency and heart failure outcomes, the study did not specifically evaluate the effectiveness of iron treatments, limiting our ability to conclude direct benefits of iron supplementation on heart failure management.
8.8
Improved energy levels
Most Useful Review
I had been suffering from anaemia, feeling constantly fatigued and with low blood pressure. My ferritin level was shockingly low at 7. After starting on iron supplements, I noticed significant improvements within weeks. My dizziness and low blood pressure improved to 110/70, and my ferritin has increased to 35. I wholeheartedly recommend this product!
Vitamin B12
4
Vitamin B12 deficiency and heart disease
Severe heart failure in a unique case of cobalamin-C-deficiency resolved with LVAD implantation and subsequent heart transplantation.
Most Relevant Research
We explored a unique case involving a young man diagnosed with Cobalamin C deficiency, a rare genetic condition affecting vitamin B12 metabolism. This condition can lead to serious health issues, including structural heart defects and severe heart failure.
Throughout his life, the patient received multiple treatments for his deficiency, including vitamin B12 supplements. However, he eventually developed severe heart failure due to dilated cardiomyopathy. Despite earlier improvements from medical treatments, his heart condition worsened, requiring advanced interventions such as a left ventricular assist device (LVAD) and ultimately a heart transplant.
Although vitamin B12 played a role in his overall treatment regime, the real focus was on managing his severe heart failure through these significant medical interventions. This case, unprecedented in its combination of LVAD implantation and heart transplant for someone with Cobalamin C deficiency, demonstrates that while vitamin B12 is essential, it is the advanced cardiac procedures that addressed the dire heart condition effectively.
In short, while vitamin B12 may improve symptoms of deficiency, advanced heart failure requires intensive medical strategies that go beyond vitamin supplementation alone.
Throughout his life, the patient received multiple treatments for his deficiency, including vitamin B12 supplements. However, he eventually developed severe heart failure due to dilated cardiomyopathy. Despite earlier improvements from medical treatments, his heart condition worsened, requiring advanced interventions such as a left ventricular assist device (LVAD) and ultimately a heart transplant.
Although vitamin B12 played a role in his overall treatment regime, the real focus was on managing his severe heart failure through these significant medical interventions. This case, unprecedented in its combination of LVAD implantation and heart transplant for someone with Cobalamin C deficiency, demonstrates that while vitamin B12 is essential, it is the advanced cardiac procedures that addressed the dire heart condition effectively.
In short, while vitamin B12 may improve symptoms of deficiency, advanced heart failure requires intensive medical strategies that go beyond vitamin supplementation alone.
9.5
Neuroprotection
Most Useful Review
Unlike cyanocobalamin, methylcobalamin is notably better absorbed and is active. It aids neuronal function and can help with conditions like Alzheimer's and heart disease. The recommended dosage is safe, and any excess is excreted. I appreciate the small, sweet tablets that dissolve effectively in my mouth for optimal absorption.
