Herbal Extracts
9.5
Lowers cholesterol levels
Most Useful Review
I regularly take this supplement with my husband, and we both notice its effect. It lowers blood cholesterol levels and improves blood flow. I recommend taking it as advised: one capsule once or twice a day, preferably in the morning and afternoon.
8.8
Cholesterol management
Most Useful Review
This product is fantastic when taken for a long course. I started with one capsule in the morning 30 minutes before meals with just water. Gradually increasing to two capsules has improved my overall health, including cholesterol levels. Ginkgo Biloba has become my essential companion for health.
Protein
9.5
Evinacumab dramatically reduces cholesterol
Dramatic response to Evinacumab in a North Indian girl with homozygous familial hypercholesterolemia.
Most Relevant Research
We explored the effectiveness of Evinacumab, a monoclonal antibody recently approved for treating severe high cholesterol. Our focus was on a 16-year-old girl from North India diagnosed with homozygous familial hypercholesterolemia (HoFH) at the tender age of two. Despite her long-standing battle with high cholesterol, traditional treatments, including medications and lifestyle changes, failed to bring her cholesterol levels down to the recommended guidelines.
Genetic testing confirmed that she had a significant mutation affecting her LDL receptor, contributing heavily to her condition. Her LDL cholesterol levels hovered around 320 mg/dL even after trying the maximum doses of established medications. As her health deteriorated, necessitating aortic valve replacement surgery, we introduced Evinacumab into her treatment regimen. What we observed was truly remarkable; her LDL cholesterol dropped by over 76%, reaching a level of 82 mg/dL that has remained stable over the last four months.
This case highlights Evinacumab as a promising option for managing patients with HoFH, especially for those who have not responded to existing therapies. This was also the first instance of a child in India receiving Evinacumab for this condition, potentially setting a precedent for future treatments.
Genetic testing confirmed that she had a significant mutation affecting her LDL receptor, contributing heavily to her condition. Her LDL cholesterol levels hovered around 320 mg/dL even after trying the maximum doses of established medications. As her health deteriorated, necessitating aortic valve replacement surgery, we introduced Evinacumab into her treatment regimen. What we observed was truly remarkable; her LDL cholesterol dropped by over 76%, reaching a level of 82 mg/dL that has remained stable over the last four months.
This case highlights Evinacumab as a promising option for managing patients with HoFH, especially for those who have not responded to existing therapies. This was also the first instance of a child in India receiving Evinacumab for this condition, potentially setting a precedent for future treatments.
8.8
Cholesterol normalised
Most Useful Review
The result is positive. After two months of taking it alongside other supplements like rice, phytosterols, and omega, my cholesterol, which was critical, became normal. Omega and rice alone didn’t work. My husband also refused statins (which he had taken for three years) and his indicators are now normal.
Nattokinase
9.5
Thinned blood
Most Useful Review
My father has had thick blood due to high cholesterol and blood clots for years. After developing diabetes post-Covid, he faced more challenges. I ordered this highly rated Nattokinase supplement for him, and within a month, he noticed his blood becoming much thinner. His blood pressure is also normalising after a long struggle with it. He is extremely pleased with the results and highly recommends this product.
9.5
Cardiovascular support
Most Useful Review
Nattokinase is an excellent enzyme for dissolving blood clots and is widely recognised in various countries. It holds great promise for thrombolytic therapy and supports overall cardiovascular health. I am pleased with the quality and effectiveness of "Doctor's Best" Nattokinase; it has exceeded my expectations.
Vitamin E
9.5
Improves blood circulation
Most Useful Review
The key feature of this product is the inclusion of "mixed tocopherols". It contains 400 IU of alpha tocopherol and other tocopherols, which are beneficial for blood circulation. Small and easy to swallow, this product is great value, particularly for those sensitive to cold. This natural alpha-tocopherol is notably effective for improving blood flow and overall health.
9.5
Lowers blood pressure
Most Useful Review
After stopping Vitamin E for three years, I noticed my blood pressure rise significantly. I resumed taking it and my systolic pressure returned to normal within two days. This Vitamin E is fantastic for maintaining healthy arteries and overall heart health as we age.
Garlic
9.5
Cholesterol normalised
Most Useful Review
I took garlic extract to support my cardiovascular system after having stents placed in my coronary vessels. The garlic proved excellent, as my cholesterol returned to normal within six months. This supplement has also been beneficial to my family and friends. Click "Yes" if this is helpful!
9.5
Blood pressure improved
Most Useful Review
This product stopped my gum bleeding and lowered my blood pressure. After three months of taking two tablets daily, my heart rate normalised, and my cholesterol reduced significantly. My dentist said my gums are healthy now. I recommend it to everyone, and we’ll continue to take it twice a year.
L Lysine
9.5
Lowers cholesterol
Most Useful Review
Perfectly reduces high cholesterol! The amino acid lysine aids in collagen formation and carbohydrate metabolism. It also inhibits the herpes simplex virus's growth and improves calcium absorption, significantly lowering osteoporosis risk. Lysine reduces serum triglycerides, thereby lowering cholesterol levels.
9.5
Herpes solution
Most Useful Review
If you suffer from herpes, lysine is the answer! I experienced attacks every 20 days until I started taking a gram twice daily. Since then, I've had no flare-ups for three months. The quality of Now’s product is excellent, although the capsules are a bit large.
Multivitamins
9.5
Healthy hair
Most Useful Review
This is a high-quality omega with essential acids for health. The quality is excellent, and I've noticed my hair has become healthier.
9.5
Supports cholesterol reduction
Most Useful Review
Organic Ester of Vitamin C with citrus bioflavonoids is an excellent choice. This vitamin C enters the body effectively and supports collagen formation and wound healing. It’s a robust antioxidant that helps lower high cholesterol and improve vascular health. I recommend taking two capsules during autumn and spring or more often if unwell. It’s an organic vitamin that does not cause harm – any excess is simply excreted.
Potassium
9.5
Blood pressure improvement
Most Useful Review
It fell as scheduled, with my blood pressure dropping from 131/82 mmHg to 113/75 mmHg. Potassium intake has been linked to managing high cholesterol. I plan to verify these results further.
9.5
Heart palpitations relief
Most Useful Review
My doctor prescribed potassium citrate for heart palpitations, which completely vanished after a week. I highly recommend it for addressing non-complicated heart issues related to high cholesterol.
Polygonum Cuspidatum Complex
8.8
Lowers cholesterol
Most Useful Review
Resveratrol reduces cholesterol, normalises blood pressure, and enhances insulin sensitivity. I recommend it!
8.8
Promising antioxidant
Most Useful Review
Resveratrol, an antioxidant in these extracts, lowers high cholesterol, normalises blood pressure, and improves insulin sensitivity, all vital during recovery from COVID-19. I’m hopeful this will enhance my health!
9.5
Joint pain relief
Most Useful Review
Switching to this omega formula improved my osteoarthritis joint pain noticeably. The folks at New Chapter explained how their pure, unrefined product contrasts with distilled fish oil supplements. I genuinely feel the difference since making the change.
8.8
Cholesterol reduction
Most Useful Review
I purchased this product to help lower my blood pressure and cholesterol levels. After three months, both lowered, showcasing the product's high quality. I have been a devoted supporter of New Chapter for over ten years, as they consistently deliver superior results.
Quercetin
9.5
Supports immunity
Most Useful Review
I found this supplement effective for my weak immunity and blood vessel issues. After using it, I had a significant improvement in health. Quercetin is a strong antioxidant that helps prevent allergies and strengthens blood vessels, making it an excellent choice. I highly recommend it for anyone needing similar support!
9
Cholesterol reduction
Most Useful Review
I take quercetin for hyperlipidemia and to lower inflammation. Since I started, my bad cholesterol fell from 250 to 170. I avoided medicinal products but I'm thrilled with these results. I advise others with similar concerns to consider trying it as it has truly helped me.
Coconut Oil
9.5
Essential for health
Most Useful Review
Coconut oil is fantastic for combating stomach bacteria. A spoonful on an empty stomach works wonders, and I even use it as mouthwash. It’s essential for hair, skin, and cooking, and I find its results to be remarkably beneficial.
9.5
Supports cholesterol levels
Most Useful Review
A quality coconut oil should be white, not yellowish, and solidifies easily as it's rich in saturated fats. Consuming it may lower high cholesterol levels and boost thyroid function. It contains medium-chain fatty acids that are easy to digest and less likely to be stored as fat.
Evening Primrose
9.5
Supports cholesterol reduction
Most Useful Review
Super Primula has been a part of my routine for women's health since 1997. It positively affects hormone balance, supports healthy pregnancies, and is effective at lowering high cholesterol levels. With its unique gamma-linolenic acid content, it significantly benefits the skin, blood vessels, and overall wellbeing. Highly recommended.
8.8
Cycle restoration
Most Useful Review
I have no complaints about the packaging, and the capsules are easy to take. After three months, I've noticed my cycle has improved, and my hair and nails are growing better. It has also led to a slight drop in my high cholesterol levels, which is encouraging.
Proprietary Blendmanna Fraxinus Ornus L)
9.5
Boosts digestion efficiency
Most Useful Review
EXCELLENT! This tincture enhances digestive processes and boosts nutrient absorption. By stimulating liver function, it increases bile and gastric juices, which helps to soften dietary fats and remove high cholesterol. I take it ten minutes before meals and recommend it.
9.5
Exceptional digestive support
Most Useful Review
Nature's Way Swedish Bitters is a game-changer! A few drops before meals revitalise me, eliminating bloating and discomfort. It has natural ingredients from a trusted brand to support digestion, including aids for high cholesterol. I am hooked and will use it daily.
Ubiquinol
9.5
Cat recovery
Most Useful Review
CoQ10 is vital for me as I’m on statins for high cholesterol. Nine years ago, my cat Oliver went into kidney failure post-surgery, and the vets gave him days to live. After researching, I started him on krill oil and CoQ10, and now, he’s thriving at 8.4kg with mostly revived kidneys. He takes his pill daily, a true survival story.
8.8
Benefits gum health
Most Useful Review
Ubiquinol is great for heart health and helps with gum infections. I take one softgel daily for gum issues and apply it directly to the affected area. If you’re on statins, it's vital to supplement with Q10/ubiquinol due to the damage statins can cause.
Vitamin K2
9.5
Prevents calcification
Most Useful Review
Vitamin K2, MK7, is essential for strengthening bones and preventing calcifications in arteries and kidneys. It helps manage calcium distribution in the body, crucial in preventing high cholesterol and related health issues. I hope my insights are helpful.
9.5
Protects arteries
Most Useful Review
Excellent for the cardiovascular system. Vitamin K2 helps redistribute calcium, removing it from the arteries and preventing high cholesterol plaques. K2 also protects against heart attacks. Stay healthy!
Spirulina
9.5
Cholesterol support
Most Useful Review
SPIRULINA-HEALTH, YOUTH AND LONGEVITY Hawaiian spirulina is exceptional and grown in pure ocean water. It boasts numerous health benefits, including supporting cardiovascular health and lowering high cholesterol. Spirulina is often regarded as the “elixir of youth," and I’ve noticed a significant increase in my vitality since starting its use.
9.5
Stress relief
Most Useful Review
I have been drinking spirulina for five months. It helps strengthen my nervous system and lowers high cholesterol. It's effective in normalising metabolism and has antiviral properties. Hawaiian spirulina is my choice due to its purity.
Flax Seed Oil
9.5
Effective treatment
Most Useful Review
A very useful product. NOW Foods Flax Oil is suitable for vegetarians and works effectively on the body. Flaxseed oil helps reduce high cholesterol and blood sugar, positively affecting heart function. Both young and old need this quality product that can be consumed daily.
9.5
Improved control
Most Useful Review
Linseed oil is praised for its omega-3 content, which can help reduce high cholesterol and triglycerides. Medical experts advise it for patients with poor blood sugar control. Despite concerns about weight gain from oil consumption, it can actually aid in weight management.
Vitamin Bs
8
Myo-inositol reduces cholesterol levels
Myo-inositol rescued insulin resistance and dyslipidemia in db/db mice.
Most Relevant Research
We wanted to understand how myo-inositol (MI), a compound found in many foods, influences cholesterol levels and overall metabolic health in db/db mice, a commonly used model for type 2 diabetes. Our findings revealed that providing MI significantly reduced high cholesterol and triglyceride levels in these mice, making a noticeable impact on their lipid profiles.
In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.
Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.
Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
9.5
Reduces back pain
Most Useful Review
This product has been fantastic! Since I began taking niacin for better sleep, my chronic back pain has vanished. I now sleep soundly through the night. My husband, who started taking it too, received alarming news about his potential collagen disease but has shown improvement since we began. Niacin has significantly alleviated our pains.
Astragalus Root
9.5
Improved kidney function
Most Useful Review
According to studies, Astragalus enhances kidney function. I initially took it for this reason, expecting no quick results, yet I experienced significant improvement. After one week, my nightly bathroom trips decreased to twice, and by the second week, it was just once. Highly recommended!
9.5
Reduces blood pressure
Most Useful Review
This remedy effectively manages high blood pressure; I bought it for my mother, who is delighted with the results. Her blood pressure readings, previously at 140-160, have improved. Sometimes it rises, but less frequently and is more manageable now. A definite positive change!
Probiotics
8
Probiotic improves offspring metabolic health
Maternal Supplementation with GG Improves Glucose Tolerance and Modulates the Intestinal Microbiota of Offspring.
Most Relevant Research
We examined how supplementing with LGG, a probiotic, affected offspring from mothers on high-calorie diets. The study used sixteen female Wistar rats, separated into different diet groups, some of which received the probiotic.
Over nine weeks, we observed that LGG not only helped manage food intake but also reduced birth weight and improved glucose sensitivity in offspring. Notably, it lowered LDL cholesterol and triglyceride levels, showing promising potential to counteract the negative effects of maternal high-calorie diets on offspring health.
Over nine weeks, we observed that LGG not only helped manage food intake but also reduced birth weight and improved glucose sensitivity in offspring. Notably, it lowered LDL cholesterol and triglyceride levels, showing promising potential to counteract the negative effects of maternal high-calorie diets on offspring health.
10
Improved cholesterol
Most Useful Review
I love it. It has greatly improved my cholesterol level. I will order for my husband.
Caprylic Acid Triglycerides
9.5
Supports cardiovascular health
Most Useful Review
MCT oil is a source of fatty acids essential for the proper functioning of all bodily systems. This product, containing medium-chain triglycerides (MCTs), is beneficial at any age. It aids weight loss, enhances endurance, protects against aging, improves brain function, and supports the cardiovascular system. MCTs are easily absorbed, help purify the body, restore beneficial gut microflora, and normalise hormone balance. They also strengthen immunity, improve nutrient absorption, and reduce bad cholesterol, lowering the risk of heart-related issues.
9.5
Improves cholesterol levels
Most Useful Review
I'm thrilled to share my experience with Bulletproof MCT Oil; it has become a vital part of my daily diet, producing amazing results. My energy levels are fantastic, with reduced fluctuations throughout the day. My focus and productivity have significantly improved. This oil enhances the taste of my coffee and smoothies, making them richer and creamier. Additionally, I've noticed improvements in my cholesterol levels and overall well-being. I wholeheartedly recommend this oil for those seeking quality to boost health and energy.
Tumeric
8
Curcumin aids cholesterol management
An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Controlled Trials Investigating the Effect of Curcumin Supplementation on Lipid Profiles.
Most Relevant Research
We explored the effects of curcumin, the active compound in turmeric, on cholesterol levels through an umbrella review of systematic reviews and meta-analyses focused on randomized controlled trials. Our objective was to assess whether curcumin supplementation could positively affect lipid profiles, particularly in relation to cholesterol levels.
In our analysis, we reviewed 26 systematic reviews, which encompassed a total of 72 randomized controlled trials. These studies compared curcumin supplementation to a placebo and measured various cholesterol components, including total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides.
Our findings indicate that curcumin does indeed exhibit an anti-lipidemic effect, especially beneficial for individuals with noncommunicable diseases. However, we noted that to achieve the best results, a curcumin formulation with enhanced bioavailability is recommended, ideally taken for at least eight weeks alongside regular exercise.
This approach presents a practical way to potentially lower the risk of atherosclerotic cardiovascular disease (ASCVD) while incorporating a natural supplement into our health routine.
In our analysis, we reviewed 26 systematic reviews, which encompassed a total of 72 randomized controlled trials. These studies compared curcumin supplementation to a placebo and measured various cholesterol components, including total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides.
Our findings indicate that curcumin does indeed exhibit an anti-lipidemic effect, especially beneficial for individuals with noncommunicable diseases. However, we noted that to achieve the best results, a curcumin formulation with enhanced bioavailability is recommended, ideally taken for at least eight weeks alongside regular exercise.
This approach presents a practical way to potentially lower the risk of atherosclerotic cardiovascular disease (ASCVD) while incorporating a natural supplement into our health routine.
8.3
Cholesterol treatment
Most Useful Review
Curcumin reduces bad cholesterol levels and slows blood clot formation. It inhibits the production of inflammatory substances. Turmeric also aids in preventing and alleviating atherosclerosis. It has proven effective in reducing and preventing metabolic syndrome.
Oleuropein
9.5
Cholesterol and weight loss
Most Useful Review
This supplement genuinely assists in lowering high cholesterol. It also supports weight loss and overall immune health.
8.8
Blood pressure improvement
Most Useful Review
I was informed that the combination of Olive Leaf and Vitamins D3 and K2 benefits high cholesterol and blood pressure. My levels have reduced since I started this supplement.
Magnesium
8.3
Eliminates bad cholesterol
Most Useful Review
Magnesium is vital for the nervous system and heart muscle. It has a vasodilator effect, normalises blood pressure, and promotes the elimination of bad cholesterol from the body.
9.5
Normalised blood pressure
Most Useful Review
Excellent help from VSD. Magnesium citrate is a lifesaver for those suffering from VSD, nervousness, and high blood pressure. I managed to lower my blood pressure to normal and my pulse from 90-110 beats per minute to 70-75. My heart has stopped racing and I no longer experience muscle cramps or eye twitches. I take three a day after meals and it has also established my bowel movements.
Flaxseed Oil
10
Lower cholesterol
Most Useful Review
Omega-3 from flaxseed oil perfectly lowers cholesterol levels.
9.5
Improved health benefits
Most Useful Review
I find this supplement excellent for all ages. My cholesterol levels have improved since I started consuming 1 to 3 capsules after each meal. Now, I have a much slimmer shape. The price is budget-friendly, and I enjoy its size and taste as well. Thank you!
Oregano
8
Oregano seed lowers cholesterol levels
Ethyl acetate fraction of oregano seed protects non-alcoholic fatty liver in high-fat diet-induced obese mice through modulation of .
Most Relevant Research
The anti-cholesterol effects of oregano seed extract were put to the test in a study involving mice on a high-fat diet. We observed that administering ethyl acetate fraction of oregano seed (OSEA) significantly impacted various cholesterol levels after ten weeks of treatment. The mice receiving 100 mg/kg of OSEA showed impressive reductions in both total cholesterol and triglyceride levels compared to those on a high-fat diet without the oregano supplement.
Not only did the body weight of the mice decrease, but their liver health improved as well, with a notable drop in liver fat content. The high-density lipoprotein (often referred to as "good" cholesterol) even showed an increase in the treated mice, indicating a positive shift in their cholesterol profile.
Furthermore, we found that OSEA affected genes linked to liver fat accumulation, reducing their expression significantly. In simpler terms, oregano may hold promise as a natural way to support cholesterol levels and promote liver health, particularly for individuals struggling with obesity or fatty liver concerns.
Not only did the body weight of the mice decrease, but their liver health improved as well, with a notable drop in liver fat content. The high-density lipoprotein (often referred to as "good" cholesterol) even showed an increase in the treated mice, indicating a positive shift in their cholesterol profile.
Furthermore, we found that OSEA affected genes linked to liver fat accumulation, reducing their expression significantly. In simpler terms, oregano may hold promise as a natural way to support cholesterol levels and promote liver health, particularly for individuals struggling with obesity or fatty liver concerns.
9.5
Digestive health
Most Useful Review
Oil of oregano is my go-to for digestive problems! Just a few drops, and it tackles bloating, cramps, and even high cholesterol. It’s like a magic potion for my stomach. Many have found relief from their digestive woes, so why not join them?
L Theanine
8
Myo-inositol reduces cholesterol levels
Myo-inositol rescued insulin resistance and dyslipidemia in db/db mice.
Most Relevant Research
We wanted to understand how myo-inositol (MI), a compound found in many foods, influences cholesterol levels and overall metabolic health in db/db mice, a commonly used model for type 2 diabetes. Our findings revealed that providing MI significantly reduced high cholesterol and triglyceride levels in these mice, making a noticeable impact on their lipid profiles.
In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.
Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.
Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
9.5
Effective relaxant
Most Useful Review
This large package lasts four months for adults, providing good value. The small capsules are easy to swallow, and taken half an hour before breakfast, the theanine works as a relaxant without causing drowsiness, instead boosting energy and mitigating depressive symptoms. The addition of inositol helps reduce high cholesterol and supports heart health.
Chromium
9.5
Weight loss success
Most Useful Review
Eat what you like but ensure you take the pills (usually two) with food. In my experience, they take three months to work, and weight falls off without diet changes. Be cautious if you have diabetes to avoid low sugar levels. I lost over 80 pounds in three months without changing my diet, and my husband lost 60 pounds during the same time. These pills can jump-start your metabolism and aid in managing high cholesterol.
9.5
Improved energy levels
Most Useful Review
As a type 2 diabetic, I started taking these ingredients to assist with insulin tolerance. I've observed excellent blood sugar levels, increased energy, and an overall improved feeling. My wife, who isn’t diabetic, also felt more energetic after starting them. I highly recommend this product for managing high cholesterol, too.
Green Tea
8.5
Reduces cholesterol
Most Useful Review
Green tea is excellent for weight loss, offering numerous health benefits such as being anti-microbial, anti-inflammatory, anti-obesity, anti-cancer, and antioxidant. It helps in reducing belly fat, total cholesterol, blood sugar levels, and insulin in the blood.
7.5
Helps lower cholesterol
Most Useful Review
The benefits of green tea extract stem largely from its high antioxidant content, which reduces oxidative stress by protecting against cell damage from free radicals. This cell damage is linked to ageing and various diseases. These antioxidants also help decrease inflammation, lower blood pressure, and inhibit fat absorption in cells, thus helping to reduce blood fat levels.
Fish Oil
7
Eicosapentaenoic Acid Enhances Endothelial Health
Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy.
Most Relevant Research
We explored the effects of eicosapentaenoic acid (EPA) on endothelial function among patients with coronary artery disease (CAD) who were already on statin therapy to manage their cholesterol levels. This study included 150 patients whose LDL cholesterol was well-controlled, but we wanted to find out if EPA could further improve vascular health, specifically by improving endothelial function, which is crucial for overall cardiovascular wellness.
To assess this, we measured the omega-3 fatty acids present in the blood and evaluated endothelial function through a test called flow-mediated dilation (FMD) of the brachial artery. For those showing impaired function and low levels of EPA and arachidonic acid, we provided an EPA supplement for three months and measured the changes.
Our findings revealed that higher levels of omega-3 fatty acids, particularly DHA and a combination of EPA and DHA, positively correlated with better endothelial function. Most importantly, the patients who received EPA therapy showed improvements in their vascular function, especially those who also had high triglycerides.
Overall, while statins effectively lower cholesterol, the addition of EPA could potentially enhance heart health even further, especially for individuals with specific lipid profiles.
To assess this, we measured the omega-3 fatty acids present in the blood and evaluated endothelial function through a test called flow-mediated dilation (FMD) of the brachial artery. For those showing impaired function and low levels of EPA and arachidonic acid, we provided an EPA supplement for three months and measured the changes.
Our findings revealed that higher levels of omega-3 fatty acids, particularly DHA and a combination of EPA and DHA, positively correlated with better endothelial function. Most importantly, the patients who received EPA therapy showed improvements in their vascular function, especially those who also had high triglycerides.
Overall, while statins effectively lower cholesterol, the addition of EPA could potentially enhance heart health even further, especially for individuals with specific lipid profiles.
8.8
Cholesterol reduction success
Most Useful Review
OMEGA-3 Double Strength has a notable DHA content, perfect for those seeking to lower high cholesterol. Its unique ratio of DHA to EPA, at 2:1, makes it stand out. I noticed improvements in my skin, hair, and dry eyes. My husband, who struggled with high cholesterol, saw positive results after two and a half months of taking Omega-3 alongside lecithin. It's essential to monitor both good and bad cholesterol levels during tests. My cat loves it too, and I believe it benefits her health as well.
Vitamin C
9
Vitamin C reduces cholesterol levels
Effect of Using Vitamin C Supplementation on Performance, Blood Parameters, Carcass Characteristics and Meat Quality of Broiler Chickens Under Heat Stress Condition: A Meta-Analysis.
Most Relevant Research
We explored how vitamin C supplementation affects cholesterol levels in broiler chickens, particularly under heat stress conditions. Through a thorough meta-analysis of 35 studies conducted between 1985 and 2023, we assessed various performance metrics, including blood parameters, carcass characteristics, and overall meat quality.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
Our findings revealed that vitamin C significantly reduced cholesterol levels in the broiler chickens subjected to heat stress. Specifically, the study reported a notable decrease in cholesterol concentrations, with a standard mean difference of -0.976, indicating a strong beneficial effect of vitamin C in managing high cholesterol.
Additionally, we noticed improvements in body weight and average daily gain among chickens receiving vitamin C when compared to those that did not. While vitamin C did not significantly impact feed intake or breast meat quality, it emerged as a valuable antioxidant that can help lower blood triglycerides and reduce cholesterol, thus promoting better overall health and growth in broilers during stressful conditions.
Ultimately, this meta-analysis supports the use of vitamin C at a recommended dosage of 250 mg/kg as an effective growth promoter and antioxidant in broiler diets under heat stress, directly influencing cholesterol management.
9.5
Supports cholesterol normalisation
Most Useful Review
This vitamin C with quercetin is excellent! Quercetin aids in various conditions, including high cholesterol, insulin regulation, and inflammation. The effects are noticeable from the outset. I use it for allergies, viral infections, and managing diabetes, finding it particularly effective when combined with vitamin C and rutin.
Zinc
8
Zinc's variable impact on cholesterol
Effect of Zinc Supplementation on Glycemic Control in Newly Diagnosed Patients With Type 2 Diabetes Mellitus.
Most Relevant Research
We conducted a study to explore the effects of zinc supplementation on cholesterol levels in newly diagnosed patients with Type 2 diabetes. In this randomized, placebo-controlled trial, 80 patients received either zinc (50 mg/day) or a placebo alongside their regular diabetes medication, metformin.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
Over a year, we measured important health indicators such as blood glucose levels and cholesterol profiles. Our findings showed that patients who took zinc saw reductions in low-density lipoprotein (LDL) cholesterol and triglycerides, marking some positive outcomes for cholesterol management. Specifically, LDL cholesterol dropped by an average of 25.06 mg/dL, and triglycerides decreased by about 22.2 mg/dL.
However, we also noted that zinc supplementation did not result in any significant changes in high-density lipoprotein (HDL) cholesterol. This means while zinc may help lower some types of "bad" cholesterol, it doesn’t seem to improve the "good" cholesterol levels. Overall, while zinc could be a useful addition to diabetes care, its effects on cholesterol levels were inconclusive, highlighting the need for further investigation.
9.5
Improves cardiovascular function
Most Useful Review
Zinc has numerous benefits for the body, including enhancing immunity, fighting against high cholesterol, and promoting cardiovascular health. It also aids brain function, skin clarity, and enhances hair and nail strength. I find Zinc Balance capsules convenient since they contain both zinc and copper, which eliminates the need to purchase copper separately.
Docosahexaenoic Acid
8
Docosahexaenoic acid’s unclear impact
Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy.
Most Relevant Research
We investigated the connection between docosahexaenoic acid (DHA) levels and endothelial function in patients with coronary artery disease (CAD) who were already on statin therapy aimed at lowering their low-density lipoprotein cholesterol (LDL-C) levels. The goal was to see how DHA, alongside eicosapentaenoic acid (EPA), could influence cholesterol management and improve blood vessel function.
The study involved 150 patients with CAD, focusing on their serum levels of omega-3 fatty acids and their ability to maintain healthy endothelial function through a measurement called flow-mediated dilation (FMD). While we noted an association between DHA levels and endothelial dysfunction, the findings indicated that DHA alone was not assessed separately; rather, it was evaluated in tandem with EPA.
Interestingly, when we administered additional EPA to patients who had low EPA/arachidonic acid (AA) levels, there was a notable improvement in their endothelial function after three months. However, our observations suggested that while DHA levels were related to overall endothelial health, the study did not quantify the specific impact of DHA alone on cholesterol levels, leaving some questions unanswered. This highlights the complexity of omega-3 fatty acids’ effects in managing high cholesterol.
The study involved 150 patients with CAD, focusing on their serum levels of omega-3 fatty acids and their ability to maintain healthy endothelial function through a measurement called flow-mediated dilation (FMD). While we noted an association between DHA levels and endothelial dysfunction, the findings indicated that DHA alone was not assessed separately; rather, it was evaluated in tandem with EPA.
Interestingly, when we administered additional EPA to patients who had low EPA/arachidonic acid (AA) levels, there was a notable improvement in their endothelial function after three months. However, our observations suggested that while DHA levels were related to overall endothelial health, the study did not quantify the specific impact of DHA alone on cholesterol levels, leaving some questions unanswered. This highlights the complexity of omega-3 fatty acids’ effects in managing high cholesterol.
9.5
High-quality ingredients
Most Useful Review
The ingredients are of high quality and suitable for adults. Without fish oil and with a pleasant taste, the package lasts for three months. I've seen excellent results in my blood tests, with improved HDL cholesterol and reduced LDL cholesterol levels. I was just about to reorder, but unfortunately, it’s not available at the moment.
Eicosapentaenoic Acid
7
Eicosapentaenoic Acid Enhances Endothelial Health
Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy.
Most Relevant Research
We explored the effects of eicosapentaenoic acid (EPA) on endothelial function among patients with coronary artery disease (CAD) who were already on statin therapy to manage their cholesterol levels. This study included 150 patients whose LDL cholesterol was well-controlled, but we wanted to find out if EPA could further improve vascular health, specifically by improving endothelial function, which is crucial for overall cardiovascular wellness.
To assess this, we measured the omega-3 fatty acids present in the blood and evaluated endothelial function through a test called flow-mediated dilation (FMD) of the brachial artery. For those showing impaired function and low levels of EPA and arachidonic acid, we provided an EPA supplement for three months and measured the changes.
Our findings revealed that higher levels of omega-3 fatty acids, particularly DHA and a combination of EPA and DHA, positively correlated with better endothelial function. Most importantly, the patients who received EPA therapy showed improvements in their vascular function, especially those who also had high triglycerides.
Overall, while statins effectively lower cholesterol, the addition of EPA could potentially enhance heart health even further, especially for individuals with specific lipid profiles.
To assess this, we measured the omega-3 fatty acids present in the blood and evaluated endothelial function through a test called flow-mediated dilation (FMD) of the brachial artery. For those showing impaired function and low levels of EPA and arachidonic acid, we provided an EPA supplement for three months and measured the changes.
Our findings revealed that higher levels of omega-3 fatty acids, particularly DHA and a combination of EPA and DHA, positively correlated with better endothelial function. Most importantly, the patients who received EPA therapy showed improvements in their vascular function, especially those who also had high triglycerides.
Overall, while statins effectively lower cholesterol, the addition of EPA could potentially enhance heart health even further, especially for individuals with specific lipid profiles.
9.5
Effective for cholesterol
Most Useful Review
Great omega! Perfect value for money, enough for 4 months! The capsules are large, lemon-flavoured, with no fishy smell or burping. After 2 weeks, my skin is noticeably moisturised, and flakiness has gone. I take it for my mother to lower her high cholesterol levels; I took 2 capsules daily for 3 months, and the test results are positive!
Omega 3
7
Eicosapentaenoic Acid Enhances Endothelial Health
Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy.
Most Relevant Research
We explored the effects of eicosapentaenoic acid (EPA) on endothelial function among patients with coronary artery disease (CAD) who were already on statin therapy to manage their cholesterol levels. This study included 150 patients whose LDL cholesterol was well-controlled, but we wanted to find out if EPA could further improve vascular health, specifically by improving endothelial function, which is crucial for overall cardiovascular wellness.
To assess this, we measured the omega-3 fatty acids present in the blood and evaluated endothelial function through a test called flow-mediated dilation (FMD) of the brachial artery. For those showing impaired function and low levels of EPA and arachidonic acid, we provided an EPA supplement for three months and measured the changes.
Our findings revealed that higher levels of omega-3 fatty acids, particularly DHA and a combination of EPA and DHA, positively correlated with better endothelial function. Most importantly, the patients who received EPA therapy showed improvements in their vascular function, especially those who also had high triglycerides.
Overall, while statins effectively lower cholesterol, the addition of EPA could potentially enhance heart health even further, especially for individuals with specific lipid profiles.
To assess this, we measured the omega-3 fatty acids present in the blood and evaluated endothelial function through a test called flow-mediated dilation (FMD) of the brachial artery. For those showing impaired function and low levels of EPA and arachidonic acid, we provided an EPA supplement for three months and measured the changes.
Our findings revealed that higher levels of omega-3 fatty acids, particularly DHA and a combination of EPA and DHA, positively correlated with better endothelial function. Most importantly, the patients who received EPA therapy showed improvements in their vascular function, especially those who also had high triglycerides.
Overall, while statins effectively lower cholesterol, the addition of EPA could potentially enhance heart health even further, especially for individuals with specific lipid profiles.
8.8
Good prevention
Most Useful Review
This Omega-3 fish oil is excellent for health. It provides adequate doses of essential fatty acids and adheres to GMP standards. While it lacks the highest concentration of Omega-3s, it's cost-effective. I use it for skin and hair beauty, and my parents take it to maintain heart health. I recommend it, just follow the instructions of taking two capsules daily with meals.
Vitamin B6
9
Vitamin B6 may improve cholesterol
Association of pyridoxal 5'-phosphate (PLP) with lipid profiles: a population-based cohort study.
Most Relevant Research
We explored the connection between Pyridoxal 5'-Phosphate (PLP), a form of Vitamin B6, and cholesterol levels by analyzing data from over 6,400 adults. Our primary focus was to understand how PLP affects low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C).
The results revealed some intriguing patterns. We found that as PLP levels increased, LDL-C levels tended to decrease significantly—by about 17.7% for every one-unit increase in PLP. In contrast, higher PLP levels were also associated with an increase in HDL-C, demonstrating a 1.95 times greater likelihood of achieving high HDL-C levels with rising PLP concentrations.
Notably, these effects were more pronounced in particular groups, such as diabetic patients and those who don't consume alcohol. However, while the study suggests potential benefits of PLP supplementation, it's important to remember that it didn't isolate PLP's effects from other influencing factors, so we can't claim that these outcomes are exclusively due to Vitamin B6.
Overall, our findings may highlight a new avenue for nutritional approaches to managing cholesterol and preventing cardiovascular issues, but additional research is needed to fully understand the implications.
The results revealed some intriguing patterns. We found that as PLP levels increased, LDL-C levels tended to decrease significantly—by about 17.7% for every one-unit increase in PLP. In contrast, higher PLP levels were also associated with an increase in HDL-C, demonstrating a 1.95 times greater likelihood of achieving high HDL-C levels with rising PLP concentrations.
Notably, these effects were more pronounced in particular groups, such as diabetic patients and those who don't consume alcohol. However, while the study suggests potential benefits of PLP supplementation, it's important to remember that it didn't isolate PLP's effects from other influencing factors, so we can't claim that these outcomes are exclusively due to Vitamin B6.
Overall, our findings may highlight a new avenue for nutritional approaches to managing cholesterol and preventing cardiovascular issues, but additional research is needed to fully understand the implications.
9.5
Effective for health
Most Useful Review
A very good, effective product. It combines Methylfolate and B12 in active forms, and the taste is pleasant. It enhances absorption and assists with high cholesterol and anaemia. I have noticed improvements in my overall wellbeing and mood.
Vitamin D3
9
Vitamin D3 reduces triglycerides and cholesterol
Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
Most Relevant Research
We evaluated how vitamin D3 supplementation influences cholesterol levels in overweight or obese women through a comprehensive meta-analysis of randomized controlled trials. Our focus was on understanding whether this vitamin could effectively improve lipid profiles, specifically high cholesterol levels.
In analyzing 13 studies, we found that vitamin D3 supplementation significantly reduced triglyceride (TG) and total cholesterol (TC) levels while also increasing high-density lipoprotein cholesterol (HDL-C), which is considered “good” cholesterol. Specifically, TG levels decreased by an average of about 6.13 mg/dL and total cholesterol levels decreased by approximately 4.45 mg/dL. Additionally, we saw a noteworthy boost in HDL-C levels, which increased by 1.54 mg/dL.
It's fascinating to note that the most notable reductions in triglycerides occurred in participants who started with higher baseline levels and those who were administered vitamin D3 for 26 weeks or less. However, we should be transparent that vitamin D3 did not show a significant effect on low-density lipoprotein cholesterol (LDL-C) concentrations, which is often a key concern in cholesterol management. Overall, our findings suggest that while vitamin D3 has a positive impact on certain aspects of lipid profiles, it may not be a comprehensive solution for all cholesterol issues.
In analyzing 13 studies, we found that vitamin D3 supplementation significantly reduced triglyceride (TG) and total cholesterol (TC) levels while also increasing high-density lipoprotein cholesterol (HDL-C), which is considered “good” cholesterol. Specifically, TG levels decreased by an average of about 6.13 mg/dL and total cholesterol levels decreased by approximately 4.45 mg/dL. Additionally, we saw a noteworthy boost in HDL-C levels, which increased by 1.54 mg/dL.
It's fascinating to note that the most notable reductions in triglycerides occurred in participants who started with higher baseline levels and those who were administered vitamin D3 for 26 weeks or less. However, we should be transparent that vitamin D3 did not show a significant effect on low-density lipoprotein cholesterol (LDL-C) concentrations, which is often a key concern in cholesterol management. Overall, our findings suggest that while vitamin D3 has a positive impact on certain aspects of lipid profiles, it may not be a comprehensive solution for all cholesterol issues.
9.5
Improves health
Most Useful Review
This high-quality dietary supplement has worked wonders for my hair loss and bone pain. Recommended by my doctor to improve immunity, I noticed health improvements within days, including better skin and hair. It's miraculous, and I plan to continue taking it.
Vitamins
8
Vitamin D's impact on cholesterol
A cohort study of serum 25-hydroxyvitamin D levels and the risk of hyperlipidaemia in adults.
Most Relevant Research
We investigated the relationship between serum levels of vitamin D and the risk of high cholesterol, or hyperlipidemia, among adults in a prospective cohort study. This research involved collecting data over three years to understand how vitamin D might influence cholesterol levels, particularly focusing on different ranges of vitamin D sufficiency.
Our findings indicated that individuals with low vitamin D levels faced a significantly higher risk of developing hyperlipidemia. Specifically, those deficient in vitamin D had over 1.5 times the risk compared to those with adequate levels of this essential vitamin.
Additionally, a notable percentage of participants were found to have vitamin D deficiency, particularly among middle-aged and older adults. This suggests a potential link between lifestyle factors accompanying low vitamin D levels and the increased likelihood of high cholesterol.
Overall, these insights point to the promising possibility of improving cholesterol profiles through adequate vitamin D intake, but further research is likely needed to develop clear treatment pathways based solely on vitamin D supplementation.
Our findings indicated that individuals with low vitamin D levels faced a significantly higher risk of developing hyperlipidemia. Specifically, those deficient in vitamin D had over 1.5 times the risk compared to those with adequate levels of this essential vitamin.
Additionally, a notable percentage of participants were found to have vitamin D deficiency, particularly among middle-aged and older adults. This suggests a potential link between lifestyle factors accompanying low vitamin D levels and the increased likelihood of high cholesterol.
Overall, these insights point to the promising possibility of improving cholesterol profiles through adequate vitamin D intake, but further research is likely needed to develop clear treatment pathways based solely on vitamin D supplementation.
10
Healthy skin
Most Useful Review
This product is excellent and has greatly benefited me. My skin, hair, and nails are healthier, and my good cholesterol has increased. The quantity is large, meaning it lasts a long time, and the price is very affordable. I highly recommend it.
Folate
8
Cholesterol reduction in children studied
Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia.
Most Relevant Research
We investigated how a special dietary supplement, which includes folate among other natural components, impacts cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, called Armolipid, combines red yeast rice, policosanols, coenzyme Q10, astaxanthin, and folic acid.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
Over the course of 16 months, we observed significant reductions in total cholesterol and some harmful types of cholesterol, including low-density lipoprotein (LDL), which is often referred to as "bad cholesterol." However, it’s important to note that despite the presence of folate in the supplement, the study did not isolate its effects from the other ingredients, making it challenging to determine folate's specific impact on high cholesterol levels.
We did not see significant changes in beneficial cholesterol levels (high-density lipoprotein or HDL), triglycerides, or other lipoproteins. For those who were using phytosterols before starting Armolipid, the supplement did provide additional benefits, particularly in reducing atherogenic lipoproteins.
Overall, while Armolipid may offer an effective and safe option for managing cholesterol in children, we should conduct further research to specifically understand the role of folate and the other ingredients separately.
9.5
Reduced homocysteine levels
Most Useful Review
My blood tests revealed elevated homocysteine, which can indicate poor lifestyle choices and heightens the risk of heart and vascular issues. I discovered I have folic acid malabsorption, so I was prescribed Methylfolate instead. After 2 weeks of taking 4000 mcg daily, my homocysteine dropped from 14 to 5.8. I now take 800 mcg per day.
Coenzyme Q10
8
Nutraceuticals show promise for children
Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia.
Most Relevant Research
In this study, we explored how a dietary supplement, which includes coenzyme Q10 among other natural ingredients, affects high cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, Armolipid, was given daily to 84 young participants, aiming to see if it could positively impact their cholesterol levels over time.
Our findings revealed that taking Armolipid led to significant decreases in total cholesterol and low-density lipoprotein cholesterol, which is often referred to as "bad" cholesterol. However, it's important to note that we didn't find any changes in high-density lipoprotein cholesterol, which is the "good" cholesterol, or in other lipid markers such as triglycerides.
Coenzyme Q10 was part of a combination treatment and its specific impact on cholesterol levels was challenging to isolate. While children who had previously used phytosterols saw additional improvements after starting Armolipid, the overall effects of coenzyme Q10 alone remain unclear.
Moving forward, more research involving larger groups of children is necessary to better understand the potential benefits of nutraceuticals like Armolipid in managing cholesterol levels in young people.
Our findings revealed that taking Armolipid led to significant decreases in total cholesterol and low-density lipoprotein cholesterol, which is often referred to as "bad" cholesterol. However, it's important to note that we didn't find any changes in high-density lipoprotein cholesterol, which is the "good" cholesterol, or in other lipid markers such as triglycerides.
Coenzyme Q10 was part of a combination treatment and its specific impact on cholesterol levels was challenging to isolate. While children who had previously used phytosterols saw additional improvements after starting Armolipid, the overall effects of coenzyme Q10 alone remain unclear.
Moving forward, more research involving larger groups of children is necessary to better understand the potential benefits of nutraceuticals like Armolipid in managing cholesterol levels in young people.
9.5
Energy production boost
Most Useful Review
BEST FRIENDS! Coenzyme Q-10 helps produce energy in the body and acts as an antioxidant. CoQ10 controls high blood pressure and maintains energy metabolism, aiding in heart health and even supporting the immune system. It is absorbed better with fats!
Silybum Marianum
7
Silibinin shows mixed diabetes effects
Silibinin as a major component of milk thistle seed provides promising influences against diabetes and its complications: a systematic review.
Most Relevant Research
We explored how silibinin, the key ingredient in milk thistle, impacts diabetes and its complications. This review examined a variety of studies and highlighted that silibinin showed promise in improving diabetes by reducing blood sugar levels and lowering cholesterol and triglycerides.
It seems silibinin enhances overall metabolic health by lowering insulin resistance and decreasing inflammation. However, while the findings are encouraging, we must acknowledge that more comprehensive research is needed to unravel the specific mechanisms at play.
It seems silibinin enhances overall metabolic health by lowering insulin resistance and decreasing inflammation. However, while the findings are encouraging, we must acknowledge that more comprehensive research is needed to unravel the specific mechanisms at play.
7.5
Decreased liver enzymes
Most Useful Review
I bought this for my mother undergoing chemotherapy due to high ASAT and ALAT levels. After using milk thistle alongside Chlorella, her liver support improved significantly, and her ASAT and ALAT levels dropped close to normal.
8
Docosahexaenoic acid’s unclear impact
Clinical Significance of Serum Omega-3 Fatty Acids on Endothelial Function in Patients with Coronary Artery Disease Under Statin Therapy.
Most Relevant Research
We investigated the connection between docosahexaenoic acid (DHA) levels and endothelial function in patients with coronary artery disease (CAD) who were already on statin therapy aimed at lowering their low-density lipoprotein cholesterol (LDL-C) levels. The goal was to see how DHA, alongside eicosapentaenoic acid (EPA), could influence cholesterol management and improve blood vessel function.
The study involved 150 patients with CAD, focusing on their serum levels of omega-3 fatty acids and their ability to maintain healthy endothelial function through a measurement called flow-mediated dilation (FMD). While we noted an association between DHA levels and endothelial dysfunction, the findings indicated that DHA alone was not assessed separately; rather, it was evaluated in tandem with EPA.
Interestingly, when we administered additional EPA to patients who had low EPA/arachidonic acid (AA) levels, there was a notable improvement in their endothelial function after three months. However, our observations suggested that while DHA levels were related to overall endothelial health, the study did not quantify the specific impact of DHA alone on cholesterol levels, leaving some questions unanswered. This highlights the complexity of omega-3 fatty acids’ effects in managing high cholesterol.
The study involved 150 patients with CAD, focusing on their serum levels of omega-3 fatty acids and their ability to maintain healthy endothelial function through a measurement called flow-mediated dilation (FMD). While we noted an association between DHA levels and endothelial dysfunction, the findings indicated that DHA alone was not assessed separately; rather, it was evaluated in tandem with EPA.
Interestingly, when we administered additional EPA to patients who had low EPA/arachidonic acid (AA) levels, there was a notable improvement in their endothelial function after three months. However, our observations suggested that while DHA levels were related to overall endothelial health, the study did not quantify the specific impact of DHA alone on cholesterol levels, leaving some questions unanswered. This highlights the complexity of omega-3 fatty acids’ effects in managing high cholesterol.
8
Relaxation benefits
Most Useful Review
My favourite adaptogenic tea from Organic India, after Tulsi Sleep, is this one. I chose it due to its composition, with the main ingredient being the SACRED BASIL or Holy Basil. This broad-spectrum herb is known for its anti-inflammatory and blood sugar-lowering properties. Most importantly, Tulsi has a calming effect, helping to lower cortisol levels in the blood, thus aiding in anxiety relief. If you are feeling STRESSED and suspect high cortisol, consider more concentrated options. However, if you're like me and suspect low cortisol, be cautious with concentrated extracts. I find this tea works for both high and low cortisol levels as it has a gentle effect. The second key ingredient is ASHWAGANDA, which regulates adrenal function and cortisol levels. I appreciate that the tea has a simpler composition, which enhances the concentration of basil and ashwagandha while offering a natural taste and aroma.
Cod Liver Oil
9
Cod liver oil aids cholesterol reduction
Role of Cod Liver Oil in Reducing Elevated Lipid Parameters.
Most Relevant Research
We conducted an insightful study to examine the effects of cod liver oil on high cholesterol levels. The research was carried out in a well-structured manner, with 600 participants who had elevated cholesterol and low-density lipoprotein (LDL) levels. These individuals were divided into two groups. One group received daily doses of 415 mg of cod liver oil along with 10 mg of rosuvastatin, while the other group received just the rosuvastatin with placebo capsules.
After 30 days, we observed compelling results. The group taking cod liver oil showed a more significant drop in total cholesterol levels compared to those who only took rosuvastatin. Specifically, their total cholesterol fell to 152.22 mg/dL compared to 171.65 mg/dL in the control group. Similarly, LDL levels decreased more in the cod liver oil group, highlighting its potential benefits when added to standard cholesterol treatment.
However, it's crucial to mention that while cod liver oil seems to enhance the effect of rosuvastatin, lifestyle changes should still be the primary focus for anyone managing high cholesterol. This study opens the door for further research to explore the specific benefits of cod liver oil in such treatments.
After 30 days, we observed compelling results. The group taking cod liver oil showed a more significant drop in total cholesterol levels compared to those who only took rosuvastatin. Specifically, their total cholesterol fell to 152.22 mg/dL compared to 171.65 mg/dL in the control group. Similarly, LDL levels decreased more in the cod liver oil group, highlighting its potential benefits when added to standard cholesterol treatment.
However, it's crucial to mention that while cod liver oil seems to enhance the effect of rosuvastatin, lifestyle changes should still be the primary focus for anyone managing high cholesterol. This study opens the door for further research to explore the specific benefits of cod liver oil in such treatments.
9.5
Best brand choice
Most Useful Review
Excellent quality! Among healthy fats, I prefer Carlson. When choosing omega-3, focus on DHA concentration, as it’s vital for the body. Ensure high EPA and DHA levels in the formula for optimal benefits in managing high cholesterol.
Red Yeast Rice
8
Nutraceuticals show promise for children
Beneficial Effects of a Nutraceutical Combination on Lipid Profiles in Children with Moderate and Severe Hypercholesterolemia.
Most Relevant Research
In this study, we explored how a dietary supplement, which includes coenzyme Q10 among other natural ingredients, affects high cholesterol levels in children and adolescents with moderate to severe hypercholesterolemia. The supplement, Armolipid, was given daily to 84 young participants, aiming to see if it could positively impact their cholesterol levels over time.
Our findings revealed that taking Armolipid led to significant decreases in total cholesterol and low-density lipoprotein cholesterol, which is often referred to as "bad" cholesterol. However, it's important to note that we didn't find any changes in high-density lipoprotein cholesterol, which is the "good" cholesterol, or in other lipid markers such as triglycerides.
Coenzyme Q10 was part of a combination treatment and its specific impact on cholesterol levels was challenging to isolate. While children who had previously used phytosterols saw additional improvements after starting Armolipid, the overall effects of coenzyme Q10 alone remain unclear.
Moving forward, more research involving larger groups of children is necessary to better understand the potential benefits of nutraceuticals like Armolipid in managing cholesterol levels in young people.
Our findings revealed that taking Armolipid led to significant decreases in total cholesterol and low-density lipoprotein cholesterol, which is often referred to as "bad" cholesterol. However, it's important to note that we didn't find any changes in high-density lipoprotein cholesterol, which is the "good" cholesterol, or in other lipid markers such as triglycerides.
Coenzyme Q10 was part of a combination treatment and its specific impact on cholesterol levels was challenging to isolate. While children who had previously used phytosterols saw additional improvements after starting Armolipid, the overall effects of coenzyme Q10 alone remain unclear.
Moving forward, more research involving larger groups of children is necessary to better understand the potential benefits of nutraceuticals like Armolipid in managing cholesterol levels in young people.
9.5
Effective cholesterol treatment
Most Useful Review
Working drug! It’s important to note that red rice extracts may inhibit the synthesis of coenzyme Q10 (CoQ10), essential for heart health. If you're taking fermented red rice, consider supplementing with 100mg of CoQ10 daily. Unlike pharmaceutical statins, the natural statins in red rice have fewer side effects. This red rice is beneficial, as it contains CoQ10.
Iron
8
Quail eggs improve maternal health
The effect of quail egg supplements enriched with marine macroalgae spinosum on the physiological condition of Sprague Dawley rats during pregnancy.
Most Relevant Research
We began by investigating how quail egg supplements enriched with marine macroalgae might influence body weight and other physiological conditions in pregnant rats. Our study involved 25 Sprague Dawley rats split into five groups, each receiving different diets, including a control group and groups that consumed quail eggs from quail fed varying percentages of macroalgae.
The results revealed that the addition of marine macroalgae, particularly at concentrations of 3%, 4%, and 5%, led to significant changes in the nutritional profile of the quail eggs. Notably, we observed an increase in iron levels, which is often considered beneficial for various physiological processes. Interestingly, these dietary changes also contributed to a decrease in cholesterol levels.
While we did see improvements in various health markers such as hemoglobin and hematocrit, which are crucial during pregnancy, it's essential to approach the findings with caution. Although iron levels went up and cholesterol levels went down in the context of this study, isolating the impact of iron alone on high cholesterol is tricky since it was part of a combined nutrient effect from the quail egg supplements.
In summary, while iron from the enriched quail eggs appears to contribute positively to the rats' physiological health, the direct relationship between iron supplementation and lower cholesterol levels requires further investigation.
The results revealed that the addition of marine macroalgae, particularly at concentrations of 3%, 4%, and 5%, led to significant changes in the nutritional profile of the quail eggs. Notably, we observed an increase in iron levels, which is often considered beneficial for various physiological processes. Interestingly, these dietary changes also contributed to a decrease in cholesterol levels.
While we did see improvements in various health markers such as hemoglobin and hematocrit, which are crucial during pregnancy, it's essential to approach the findings with caution. Although iron levels went up and cholesterol levels went down in the context of this study, isolating the impact of iron alone on high cholesterol is tricky since it was part of a combined nutrient effect from the quail egg supplements.
In summary, while iron from the enriched quail eggs appears to contribute positively to the rats' physiological health, the direct relationship between iron supplementation and lower cholesterol levels requires further investigation.
9.5
Normalised hemoglobin levels
Most Useful Review
After trying many iron supplements, this one was the best for its taste, price, and quality. One package sufficed to replenish my iron, raising my hemoglobin to normal within a month. I've not seen this level with chronic anaemia for ages. The price was attractive at 200 rubles, so I ordered one for my husband as well. The information is in English, but it's easy to research online.
Elderberry
8
Elderberry supports healthy cholesterol
Elder (Sambucus nigra), identified by high-content screening, counteracts foam cell formation without promoting hepatic lipogenesis.
Most Relevant Research
We set out to explore how elderberry, specifically extracts from its flowers and leaves, influences cholesterol levels, particularly in the context of atherosclerosis—a condition where cholesterol builds up in our arteries.
To discover natural substances that could boost cholesterol management, we screened plant extracts for their ability to enhance cholesterol efflux in macrophages, which are cells that can become foam cells when they accumulate too much cholesterol. We found that elderberry extracts increased the expression of a key protein called ABCA1, which aids in this efflux process and consequently reduces foam cell formation.
Importantly, not only did elderberry show promise in promoting healthy cholesterol flow, but it did so without triggering excessive fat production in the liver, which is usually a concern with some treatments. Our findings suggest that elderberry can be a supportive ally in maintaining heart health by helping macrophages manage cholesterol more effectively.
In addition, we identified certain compounds within elderberry, like chlorogenic acid isomers and rutin, which may be behind its beneficial effects. Overall, our research shines a light on elderberry as a natural option for those looking to improve their cholesterol levels without unwanted side effects.
To discover natural substances that could boost cholesterol management, we screened plant extracts for their ability to enhance cholesterol efflux in macrophages, which are cells that can become foam cells when they accumulate too much cholesterol. We found that elderberry extracts increased the expression of a key protein called ABCA1, which aids in this efflux process and consequently reduces foam cell formation.
Importantly, not only did elderberry show promise in promoting healthy cholesterol flow, but it did so without triggering excessive fat production in the liver, which is usually a concern with some treatments. Our findings suggest that elderberry can be a supportive ally in maintaining heart health by helping macrophages manage cholesterol more effectively.
In addition, we identified certain compounds within elderberry, like chlorogenic acid isomers and rutin, which may be behind its beneficial effects. Overall, our research shines a light on elderberry as a natural option for those looking to improve their cholesterol levels without unwanted side effects.
7.5
Lowered cholesterol
Most Useful Review
I purchased this expecting it to lower my cholesterol and prevent colds. Mixing the powder with yoghurt made for a sweet and tangy drink. It was enjoyable and I'm planning to buy it again during the cold season.