 NOW Foods, Vitamin D-3, High Potency, 5,000 IU, 120 Softgels | | |
Calcitriol reduces age-related hypertensionCalcitriol reverses age-related hypertension via downregulating renal AP1/ATR pathway through regulating mitochondrial function. We explored the role of calcitriol, the active form of vitamin D, in addressing age-related hypertension. The study involved young and aged male mice, where we administered calcitriol daily for eight weeks. Our goal was to determine if this vitamin could effectively lower high blood pressure that often comes with aging.
Throughout the research, we measured blood pressure and examined various biological markers in the kidneys. What we discovered was quite promising. Aged mice exhibited increased blood pressure and impaired sodium excretion, both linked to changes in certain kidney pathways. After treatment with calcitriol, these mice showed significant reductions in blood pressure and improvements in sodium handling.
Mechanistically, calcitriol appeared to enhance mitochondrial function and alter the behavior of specific proteins related to blood pressure regulation. By promoting healthier kidney function and reducing harmful signaling pathways, calcitriol seems to offer a viable strategy for tackling hypertension as we age.
Overall, our findings suggest that calcitriol could be a valuable addition to our approaches in managing age-related hypertension, reaffirming the importance of vitamin D for our health as we get older. Supports COVID recovery Most Useful Review 1 people found this helpful My family and I took vitamin D during our COVID illness, and we all recovered well, even my dad with hypertension. This vitamin seemed to support our recovery and overall health. |
 Solgar, Vitamin D 3 (Cholecalciferol), 25 mcg (1,000 IU), 100 Softgels | | |
Calcitriol reduces age-related hypertensionCalcitriol reverses age-related hypertension via downregulating renal AP1/ATR pathway through regulating mitochondrial function. We explored the role of calcitriol, the active form of vitamin D, in addressing age-related hypertension. The study involved young and aged male mice, where we administered calcitriol daily for eight weeks. Our goal was to determine if this vitamin could effectively lower high blood pressure that often comes with aging.
Throughout the research, we measured blood pressure and examined various biological markers in the kidneys. What we discovered was quite promising. Aged mice exhibited increased blood pressure and impaired sodium excretion, both linked to changes in certain kidney pathways. After treatment with calcitriol, these mice showed significant reductions in blood pressure and improvements in sodium handling.
Mechanistically, calcitriol appeared to enhance mitochondrial function and alter the behavior of specific proteins related to blood pressure regulation. By promoting healthier kidney function and reducing harmful signaling pathways, calcitriol seems to offer a viable strategy for tackling hypertension as we age.
Overall, our findings suggest that calcitriol could be a valuable addition to our approaches in managing age-related hypertension, reaffirming the importance of vitamin D for our health as we get older. Health benefits noted Most Useful Review 8 people found this helpful No vitamin enhances health or well-being like vitamin D (vitamin D3 or cholecalciferol). Research indicates that it may play a vital role in preventing SARS and upper respiratory infections. Studies show that individuals with higher levels of vitamin D have a reduced risk of heart attack, breast cancer, colon cancer, multiple sclerosis, type 1 and type 2 diabetes, and hypertension. I bought vitamin D3 during the pandemic; the capsules are small and easy to swallow, ideally taken with fatty foods. |
 NOW Foods, Super Omega 3-6-9, 1,200 mg, 90 Softgels | | |
Improves blood flow Most Useful Review 1 people found this helpful Omega-3-6-9 helps dilate blood vessels, increasing blood flow to organs and tissues, thereby preventing hypertension. It positively impacts the heart, reduces arrhythmias, and lowers the risk of atherosclerosis, coronary heart disease, myocardial infarction, and stroke. Omega-9 also decreases bad cholesterol levels in the blood. Normalises BP Most Useful Review The capsules are easy to swallow. I noticed an immediate effect that not only gives me strength but also normalises my blood pressure. I recommend it for anyone with hypertension! |
 Doctor's Best, Natto-Serra, 90 Veggie Caps | | |
Nattokinase reduces blood pressureEffects of nattokinase on blood pressure: a randomized, controlled trial. We evaluated how nattokinase affects blood pressure in people living with pre-hypertension or stage 1 hypertension. In this randomized, double-blind, placebo-controlled trial involving 86 participants, we found that those taking nattokinase showed a significant drop in both systolic and diastolic blood pressure after 8 weeks. Specifically, systolic blood pressure decreased by an average of 5.55 mmHg, while diastolic blood pressure fell by 2.84 mmHg. Our results suggest that nattokinase could be a beneficial option in managing hypertension. Lowered hypertension Most Useful Review 7 people found this helpful This product has been a revelation; my modest hypertension has dramatically reduced. After months of use, my doctor was very pleased during my last visit. |
 Doctor's Best, Nattokinase, 2,000 FUs, 270 Veggie Caps | | |
Nattokinase reduces blood pressureEffects of nattokinase on blood pressure: a randomized, controlled trial. We evaluated how nattokinase affects blood pressure in people living with pre-hypertension or stage 1 hypertension. In this randomized, double-blind, placebo-controlled trial involving 86 participants, we found that those taking nattokinase showed a significant drop in both systolic and diastolic blood pressure after 8 weeks. Specifically, systolic blood pressure decreased by an average of 5.55 mmHg, while diastolic blood pressure fell by 2.84 mmHg. Our results suggest that nattokinase could be a beneficial option in managing hypertension. Improved blood pressure Most Useful Review 188 people found this helpful I use nattokinase as an alternative to aspirin for thick blood to improve fluidity. High blood viscosity increases the risk of hypertension, myocardial infarction, and stroke. I take it in the evening after dinner and in the morning on an empty stomach with serrapeptase, and I have forgotten about my blood pressure issues! |
 NOW Foods, Double Strength DHA-500 Fish Oil, 180 Softgels | | |
Eicosapentaenoic acid benefits hypertension5,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP signaling pathway. We investigated the impact of eicosapentaenoic acid (EPA) on hypertension, a condition characterized by elevated blood pressure that can lead to serious health issues. The study focused on a special compound called 5,6-diHETE lactone (EPA-L), derived from EPA, which we observed to promote better blood vessel function. This compound was tested on hypertensive rats and showed a significant reduction in blood pressure.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health. Healthy brain development Most Useful Review 3 people found this helpful Necessary for pregnant women! From conception to 2 years, consuming DHA is vital for a child’s brain, nervous system, and eye development. The World Health Organization recommends at least 500 mg of DHA daily for pregnant and breastfeeding women. A study from the University of Kansas demonstrated that a daily intake of 600 mg of DHA during pregnancy aids heart development and may protect against hypertension with excess weight. |
 NOW Foods, Folic Acid, 800 mcg, 250 Tablets | | |
Folic acid effects on hypertensionThe impact of folic acid/VB12 deficiency on essential hypertension in children and adolescents: from a nested case-control and a cohort study. We explored how low levels of folic acid (FA) and Vitamin B12 (VB12) relate to high blood pressure (BP) in children and adolescents. Conducting both nested case-control and cohort studies, we focused on primary school participants. In our research, we found that children with elevated BP exhibited lower levels of FA and VB12 compared to those with normal BP.
Interestingly, overweight or obese children with high BP had even lower levels of FA than their counterparts with healthy BP. We also noticed a correlation between FA and healthy lipid profiles, suggesting that adequate FA could help in regulating blood pressure. After adjusting for VB12 levels and homocysteine, FA alone showed a significant relationship with elevated BP.
In the cohort study, we observed that participants with high FA levels consistently had lower systolic and diastolic BP levels compared to those with low FA levels. Our findings indicate that maintaining adequate levels of folic acid and vitamin B12 during childhood is crucial, not only through diet but also possibly via supplementation, to help prevent hypertension in the future. Lowers blood pressure Most Useful Review Folic acid, a synthetic form of folate, is crucial for the formation of new cells. Insufficient folic acid may heighten the risk of cardiovascular diseases, including hypertension. Research indicates that folic acid might assist in reducing high blood pressure by relaxing arterial walls, hence lowering pressure. The jar is also economically sized. I highly recommend this product. |
 Jarrow Formulas, Curcumin 95, Turmeric Extract, 500 mg, 120 Veggie Capsules | | |
Turmeric supports blood pressure managementCurcumin/turmeric supplementation could improve blood pressure and endothelial function: A grade-assessed systematic review and dose-response meta-analysis of randomized controlled trials. We explored the potential benefits of turmeric, particularly curcumin, in managing hypertension through a systematic review and meta-analysis of randomized controlled trials. This rigorous examination pulled together findings from several studies to better understand how turmeric could influence blood pressure and related heart health factors.
Our focus was on key indicators such as systolic and diastolic blood pressure, flow-mediated vasodilation, and the levels of certain adhesion molecules that could predict vascular health. By using various reputable online databases, we gathered a wide range of data to offer a comprehensive view of turmeric's effectiveness.
The findings suggest that turmeric supplementation could indeed play a supportive role in improving blood pressure and endothelial function. However, it's essential to note that more research is required to fully understand its impact on inflammatory adhesion molecules in the bloodstream. Significant improvement Most Useful Review I bought this for my father, who has type 2 diabetes mellitus and hypertension. After two weeks of taking it, he reported feeling much better. |
 Doctor's Best, High Absorption Magnesium, 200 mg, 120 Tablets, (100 mg per Tablet) | | |
Magnesium intake linked to reduced hypertensionAssociations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia. We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns. Insulin Sensitivity Most Useful Review 4 people found this helpful I always buy magnesium for my elderly mother with diabetes. It enhances tissue sensitivity to insulin and has helped lessen her reliance on insulin injections while keeping hypertension at bay. I recommend it especially for women. |
 Nature Made, Magnesium, 250 mg, 200 Tablets | | |
Magnesium intake linked to reduced hypertensionAssociations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia. We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns. Reduces hypertension risk Most Useful Review Magnesium deficiency can increase the risk of hypertension and other serious conditions. Replenishing magnesium helps combat emotional and physical stress and supports nervous, muscle, and cardiovascular functions. |
 Nature's Bounty, Magnesium, 500 mg, 100 Coated Tablets | | |
Magnesium intake linked to reduced hypertensionAssociations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia. We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns. Heart and vessel support Most Useful Review I am 45 years old and take magnesium for hypertension as prescribed by my doctor. He recommended this product from iHerb. Magnesium positively influences heart and blood vessel function. |
 NOW Foods, Magnesium Caps, 400 mg, 180 Veg Capsules | | |
Magnesium intake linked to reduced hypertensionAssociations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia. We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns. Indispensable mineral Most Useful Review 1 people found this helpful Magnesium is indispensable for managing hypertension. NOW Foods provides an excellent option without equal. |
 NOW Foods, Magnesium Citrate, 400 mg, 120 Veg Capsules (133 mg per Capsule) | | |
Magnesium intake linked to reduced hypertensionAssociations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia. We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns. Supports overall wellbeing Most Useful Review 18 people found this helpful I'm not feeling as hungry and I'm sleeping well! Magnesium plays a key role in supporting good sleep and relieving stress, which is helpful for those with hypertension. It has notably improved my daily activities and reduced menstrual cramps, and I often share it with my family. Just remember, moderation is crucial to avoid overdose. |
 Natrol, Omega-3 Fish Oil, Lemon, 1,000 mg, 150 Softgels | | |
Eicosapentaenoic acid benefits hypertension5,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP signaling pathway. We investigated the impact of eicosapentaenoic acid (EPA) on hypertension, a condition characterized by elevated blood pressure that can lead to serious health issues. The study focused on a special compound called 5,6-diHETE lactone (EPA-L), derived from EPA, which we observed to promote better blood vessel function. This compound was tested on hypertensive rats and showed a significant reduction in blood pressure.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health. Effective against hypertension Most Useful Review Omega-3 Fish Oil works brilliantly! I prescribe it to my patients with cardiovascular issues, including hypertension and arrhythmias. It's important to remember that individuals may have a specific intolerance to the components of the medication. |
 Jarrow Formulas, Fish Oil, EPA-DHA Balance®, 120 Softgels | | |
Eicosapentaenoic acid benefits hypertension5,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP signaling pathway. We investigated the impact of eicosapentaenoic acid (EPA) on hypertension, a condition characterized by elevated blood pressure that can lead to serious health issues. The study focused on a special compound called 5,6-diHETE lactone (EPA-L), derived from EPA, which we observed to promote better blood vessel function. This compound was tested on hypertensive rats and showed a significant reduction in blood pressure.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health. Improved blood pressure Most Useful Review 3 people found this helpful The best vascular protector! Without omega acids, our life in adulthood loses its pleasure: hypertension, stenocardia, and other issues. I take this medication year-round: my blood pressure is normal, my cardiovascular performance has improved, and even my joints have stopped grinding! I also give it to my elderly parents. The dosage and number of capsules are very convenient. I searched for a suitable mono drug for ages due to my allergy to multivitamins, and I found it only on this site. I recommend these drugs to all my relatives and friends, as well as to you, dear site users! Stay healthy and happy! |
 NOW Foods, Omega-3 Fish Oil, 1,000 mg, 180 EPA - 120 DHA, 100 Softgels | | |
Eicosapentaenoic acid benefits hypertension5,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP signaling pathway. We investigated the impact of eicosapentaenoic acid (EPA) on hypertension, a condition characterized by elevated blood pressure that can lead to serious health issues. The study focused on a special compound called 5,6-diHETE lactone (EPA-L), derived from EPA, which we observed to promote better blood vessel function. This compound was tested on hypertensive rats and showed a significant reduction in blood pressure.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health. Pressure increased Most Useful Review 3 people found this helpful I have hypertension and have been taking Omega-3 capsules for a month alongside coenzyme Q10. They are large but easy to swallow, and I haven't experienced any side effects. Since starting, my palpitations have ceased, and my blood pressure has decreased. I'll continue taking them. |
 NOW Foods, Certified Organic Inulin, Prebiotic Pure Powder, 8 oz (227 g) | | |
Inulin reduces pulmonary hypertension effectsHigh-Soluble-Fiber Diet Attenuates Hypoxia-Induced Vascular Remodeling and the Development of Hypoxic Pulmonary Hypertension. We explored how a high-soluble-fiber diet, specifically one rich in inulin, impacts pulmonary hypertension in a controlled study involving mice. After feeding them diets with either 0% or 16.9% inulin, we exposed the mice to hypoxic conditions for 21 days, aiming to see if inulin could lessen the effects of pulmonary hypertension brought on by low oxygen levels.
Our findings showed that the mice on the high-soluble-fiber diet experienced lower right ventricular systolic pressure and reduced pulmonary vascular resistance compared to those on the low-fiber diet. Notably, this dietary change altered the gut microbiome, promoting bacteria that produce beneficial short-chain fatty acids and decreasing harmful bacteria associated with disease. We also observed a decrease in certain inflammatory immune cells in the lungs, which may contribute to the positive effects on vascular remodeling.
This study presents exciting evidence that a high-soluble-fiber diet, particularly one rich in inulin, may have the potential to mitigate the effects of pulmonary hypertension caused by hypoxia. These results suggest that dietary choices can play a significant role in managing vascular health and highlight the significance of nutrients like inulin in improving overall lung function. Positive digestive effects Most Useful Review By optimising inulin in my diet, I have found it can help reduce the risk of developing arterial hypertension and other cardiovascular diseases. I also noticed inulin's beneficial effects on the digestive system, promoting the growth of healthy intestinal microflora and enhancing digestion. |
 NOW Foods, Calcium & Magnesium, 250 Tablets | | |
Magnesium intake linked to reduced hypertensionAssociations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia. We explored the connection between dietary magnesium intake and hypertension along with other health issues in US adults. In our study, we analyzed data from over 24,000 people, taking into account various lifestyle factors.
We found that those with higher magnesium intake had significantly lower rates of hypertension, diabetes, and hyperlipidemia compared to those with the least intake. Notably, participants in the highest quintile of magnesium consumption were less likely to suffer from these conditions.
These results suggest that increasing magnesium-rich foods in our diets could help prevent these prevalent health concerns. Reduced headaches Most Useful Review I am very satisfied with this product, and I've even ordered it for my mum as a supplement for her hypertension! Since she started, her headaches have noticeably decreased! |
 NOW Foods, Potassium Citrate, 99 mg, 180 Veg Capsules | | |
Brief education aids hypertension management"Minimal-Advice" on Salt Intake: Results of a Multicentre Pilot Randomised Controlled Trial on Hypertensive Patients. We aimed to see how a quick educational session with a physician could influence dietary habits in hypertensive patients. Through a study involving 230 participants, we split them into two groups: those who received educational interventions and a control group.
After just one consultation, we observed promising results—a decrease in salt intake, improved blood pressure readings, and an increase in potassium consumption among those who received guidance. Importantly, there were no adverse effects noted from this approach. Alleviates chest pain Most Useful Review 4 people found this helpful I drink this for hypertension when I've consumed too much salt. It really helps relieve the chest tightness I experience. |
 Sports Research, Omega-3 Fish Oil, Triple Strength , 30 Softgels | | |
Eicosapentaenoic acid benefits hypertension5,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP signaling pathway. We investigated the impact of eicosapentaenoic acid (EPA) on hypertension, a condition characterized by elevated blood pressure that can lead to serious health issues. The study focused on a special compound called 5,6-diHETE lactone (EPA-L), derived from EPA, which we observed to promote better blood vessel function. This compound was tested on hypertensive rats and showed a significant reduction in blood pressure.
Interestingly, we found that the way EPA-L works isn’t through increasing levels of nitric oxide like some may expect. Instead, we discovered that it triggers a unique signaling pathway involving G-protein-coupled receptors. This pathway activates key cellular processes in the endothelial cells lining our blood vessels, allowing them to relax and dilate, thereby contributing to lower blood pressure. In vitro experiments on human endothelial cells confirmed these findings, providing further evidence for the effectiveness of EPA-L.
Overall, our research positions EPA-L as a promising metabolite from eicosapentaenoic acid, demonstrating potential benefits in managing hypertension and promoting vascular health. Essential for hypertension Most Useful Review Excellent! Omega-3 becomes an essential supplement after a certain age, particularly for individuals with hypertension. |
 Kyolic, Aged Garlic Extract, Blood Pressure Health, Formula 109, 160 Capsules | | |
Nattokinase reduces blood pressureEffects of nattokinase on blood pressure: a randomized, controlled trial. We evaluated how nattokinase affects blood pressure in people living with pre-hypertension or stage 1 hypertension. In this randomized, double-blind, placebo-controlled trial involving 86 participants, we found that those taking nattokinase showed a significant drop in both systolic and diastolic blood pressure after 8 weeks. Specifically, systolic blood pressure decreased by an average of 5.55 mmHg, while diastolic blood pressure fell by 2.84 mmHg. Our results suggest that nattokinase could be a beneficial option in managing hypertension. Improved blood pressure Most Useful Review 3 people found this helpful Kyolic-aged-garlic-extract is beneficial for lowering blood pressure in patients with uncontrolled hypertension. Moreover, it may enhance arterial stiffness, inflammation, and the gut microbial profile. |
 Kyolic, Aged Garlic Extract™, Cardiovascular Health, Original Formula 100, 600 mg, 300 Capsules (300 mg Per Capsule) | | |
Aged garlic extract lowers blood pressureEffects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials. We examined the effects of aged garlic extract (AGE) on blood pressure in individuals with hypertension through a thorough review of randomized controlled trials (RCTs). Our analysis included data from various studies, ultimately bringing together results from nine trials that involved a total of 584 participants.
The findings indicated that supplementation with AGE tea could lead to reductions in both systolic and diastolic blood pressure. Specifically, we noted a decrease in systolic blood pressure by an average of 4.03 mmHg and a slight reduction in diastolic blood pressure by 1.44 mmHg. However, the most significant improvements were observed with daily doses exceeding 1200 mg.
Given that the overall data suggest positive outcomes for those with hypertension, particularly at higher dosages, we believe that AGE could be a beneficial addition to lifestyle and dietary strategies for managing high blood pressure. That said, further, well-designed clinical trials are necessary to validate these results and establish clearer recommendations. Blood pressure control Most Useful Review 19 people found this helpful I have been taking Kiol garlic for over a year and a half, and my latest blood pressure reading was an impressive 128/74 without additional medication. Previously, I struggled with hypertension, often exceeding 160 bp while on Lisinopril. Now, at 28, I feel significantly better thanks to garlic, which I take twice a day. I also focus on a healthy diet and hydration, but the benefits of Kiol garlic far outweigh any pharmaceutical side effects. It truly has saved my life, and I am incredibly grateful. |
 NOW Foods, Odorless Garlic, Concentrated Extract, 50 mg, 250 Softgels (25 mg per Softgel) | | |
Aged garlic extract lowers blood pressureEffects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials. We examined the effects of aged garlic extract (AGE) on blood pressure in individuals with hypertension through a thorough review of randomized controlled trials (RCTs). Our analysis included data from various studies, ultimately bringing together results from nine trials that involved a total of 584 participants.
The findings indicated that supplementation with AGE tea could lead to reductions in both systolic and diastolic blood pressure. Specifically, we noted a decrease in systolic blood pressure by an average of 4.03 mmHg and a slight reduction in diastolic blood pressure by 1.44 mmHg. However, the most significant improvements were observed with daily doses exceeding 1200 mg.
Given that the overall data suggest positive outcomes for those with hypertension, particularly at higher dosages, we believe that AGE could be a beneficial addition to lifestyle and dietary strategies for managing high blood pressure. That said, further, well-designed clinical trials are necessary to validate these results and establish clearer recommendations. Improved immunity Most Useful Review 1 people found this helpful I give Beru Mame to my mother, who has hypertension. She finds it superior to pills as garlic helps regulate blood pressure and thins the blood. It also boosts immunity during colds, which makes her quite happy. |
 NOW Foods, Garlic Oil, 1,500 mg, 250 Softgels | | |
Aged garlic extract lowers blood pressureEffects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials. We examined the effects of aged garlic extract (AGE) on blood pressure in individuals with hypertension through a thorough review of randomized controlled trials (RCTs). Our analysis included data from various studies, ultimately bringing together results from nine trials that involved a total of 584 participants.
The findings indicated that supplementation with AGE tea could lead to reductions in both systolic and diastolic blood pressure. Specifically, we noted a decrease in systolic blood pressure by an average of 4.03 mmHg and a slight reduction in diastolic blood pressure by 1.44 mmHg. However, the most significant improvements were observed with daily doses exceeding 1200 mg.
Given that the overall data suggest positive outcomes for those with hypertension, particularly at higher dosages, we believe that AGE could be a beneficial addition to lifestyle and dietary strategies for managing high blood pressure. That said, further, well-designed clinical trials are necessary to validate these results and establish clearer recommendations. Reduces hypertension Most Useful Review 44 people found this helpful Garlic possesses numerous benefits, such as strengthening the immune system, aiding in colds, protecting cardiovascular health, and eliminating bacteria. It decreases cholesterol production while promoting the absorption of "bad" cholesterol, thus lowering the risk of both atherosclerosis and hypertension. A major study revealed that daily garlic supplementation led to a 63% decline in cold occurrences. |
 Jarrow Formulas, Vegan Red Yeast Rice + Co-Q10, 120 Veggie Capsules | | |
Citicoline and CoQ10 protection studyNeuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension. We investigated how a combination of citicoline and coenzyme Q10 (CoQ10) might impact retinal cell health in a mouse model of ocular hypertension (OHT). Using four groups of mice, including those receiving the combination treatment and a control group, we aimed to understand if these substances could protect against the loss of retinal ganglion cells, which is a major concern in glaucoma.
The treatment was started 15 days prior to inducing ocular hypertension with a laser and continued until we examined the mice about a week later. Our findings were promising: the combination of citicoline and CoQ10 led to a temporary reduction in eye pressure shortly after treatment. Furthermore, it significantly prevented the death of specific retinal cells that are vital for vision.
While we were encouraged by these results, especially regarding cell protection, it's important to note that there were no significant impacts on neurons in the visual pathway areas we studied, like the dLGN. Overall, our research suggests that this combination might offer neuroprotective benefits in specific aspects of ocular hypertension, paving the way for further exploration into treatments that go beyond only lowering eye pressure. No side effects Most Useful Review 1 people found this helpful Good purchase. The doctor prescribed this for my hypertension, aiming to gradually replace hypertene with red yeast. This product hasn’t caused any side effects, allergies, or rejections and has met its objective. It’s also free from excipients and offers great value for money. |
 Doctor's Best, High Absorption CoQ10 with BioPerine®, 100 mg, 120 Veggie Caps | | |
Citicoline and CoQ10 protection studyNeuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension. We investigated how a combination of citicoline and coenzyme Q10 (CoQ10) might impact retinal cell health in a mouse model of ocular hypertension (OHT). Using four groups of mice, including those receiving the combination treatment and a control group, we aimed to understand if these substances could protect against the loss of retinal ganglion cells, which is a major concern in glaucoma.
The treatment was started 15 days prior to inducing ocular hypertension with a laser and continued until we examined the mice about a week later. Our findings were promising: the combination of citicoline and CoQ10 led to a temporary reduction in eye pressure shortly after treatment. Furthermore, it significantly prevented the death of specific retinal cells that are vital for vision.
While we were encouraged by these results, especially regarding cell protection, it's important to note that there were no significant impacts on neurons in the visual pathway areas we studied, like the dLGN. Overall, our research suggests that this combination might offer neuroprotective benefits in specific aspects of ocular hypertension, paving the way for further exploration into treatments that go beyond only lowering eye pressure. Significant improvement Most Useful Review 281 people found this helpful My mother had a heart attack two years ago and suffered from various heart conditions and constant arrhythmia. After starting coenzyme Q10, her attacks stopped within five months, and her overall health improved significantly. She took it alongside Omega 3 and other supplements. We found that 100 mg daily works well, and buying from iHerb has been far more affordable than in Russia. |
 NOW Foods, CoQ10 with Hawthorn Berry, 100 mg, 90 Veg Capsules | | |
Citicoline and CoQ10 protection studyNeuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension. We investigated how a combination of citicoline and coenzyme Q10 (CoQ10) might impact retinal cell health in a mouse model of ocular hypertension (OHT). Using four groups of mice, including those receiving the combination treatment and a control group, we aimed to understand if these substances could protect against the loss of retinal ganglion cells, which is a major concern in glaucoma.
The treatment was started 15 days prior to inducing ocular hypertension with a laser and continued until we examined the mice about a week later. Our findings were promising: the combination of citicoline and CoQ10 led to a temporary reduction in eye pressure shortly after treatment. Furthermore, it significantly prevented the death of specific retinal cells that are vital for vision.
While we were encouraged by these results, especially regarding cell protection, it's important to note that there were no significant impacts on neurons in the visual pathway areas we studied, like the dLGN. Overall, our research suggests that this combination might offer neuroprotective benefits in specific aspects of ocular hypertension, paving the way for further exploration into treatments that go beyond only lowering eye pressure. Improved blood circulation Most Useful Review 6 people found this helpful Excellent! I take courses of coenzyme Q10, as its production decreases with age, and it's very beneficial for energy and well-being. Additionally, hawthorn is included, which positively affects cardiovascular health, enhances blood circulation, and can assist with hypertension. I highly recommend it! A like would be appreciated if you find this review helpful. Wishing you all successful and beneficial shopping! |
 Jarrow Formulas, Vegan Co-Q10, 200 mg, 60 Veggie Capsules | | |
Citicoline and CoQ10 protection studyNeuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension. We investigated how a combination of citicoline and coenzyme Q10 (CoQ10) might impact retinal cell health in a mouse model of ocular hypertension (OHT). Using four groups of mice, including those receiving the combination treatment and a control group, we aimed to understand if these substances could protect against the loss of retinal ganglion cells, which is a major concern in glaucoma.
The treatment was started 15 days prior to inducing ocular hypertension with a laser and continued until we examined the mice about a week later. Our findings were promising: the combination of citicoline and CoQ10 led to a temporary reduction in eye pressure shortly after treatment. Furthermore, it significantly prevented the death of specific retinal cells that are vital for vision.
While we were encouraged by these results, especially regarding cell protection, it's important to note that there were no significant impacts on neurons in the visual pathway areas we studied, like the dLGN. Overall, our research suggests that this combination might offer neuroprotective benefits in specific aspects of ocular hypertension, paving the way for further exploration into treatments that go beyond only lowering eye pressure. Supports hypertension treatment Most Useful Review 1 people found this helpful Best of the Q10 options. This isn't the first time I've ordered for my mother; she requires it regularly for hypertension and cardiovascular issues. Those with varicose veins may also benefit. The effective dosage is 200 mg, taken in the morning after a breakfast that must include fats. Prior to taking, one should consume l-carnitine for better absorption of Q10. For enhanced results, I alternate between Q10 and the PQQ + Q10 regimen. We follow this in courses. It's essential to consult a healthcare practitioner knowledgeable about supplements before use. This review might be helpful; I like it. |
 NOW Foods, Ubiquinol, 100 mg, 120 Softgels | | |
Ubiquinol shows partial benefitsSex-Dependent Protective Effect of Combined Application of Solubilized Ubiquinol and Selenium on Monocrotaline-Induced Pulmonary Hypertension in Wistar Rats. We explored the impact of ubiquinol on pulmonary hypertension using a model that mimics this serious condition. In our study, rats were injected with monocrotaline, a substance known to induce pulmonary hypertension. Over the course of the experiment, we provided various groups of these rats with different treatments, including solubilized ubiquinol and selenium, to see how these substances could protect against the effects of the disease.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism. Highly effective Most Useful Review 1 people found this helpful Excellent quality and dosage. I highly recommend it for managing hypertension, especially in conjunction with PQQ. |
 Jarrow Formulas, Taurine , 1,000 mg, 100 Capsules | | |
Regulates hypertension Most Useful Review Excellent! We use taurine as a means to regulate hypertension effectively. Strengthens immune system Most Useful Review Taurine is very effective, positively impacting oedema, heart issues, hypertension, and hypoglycaemia. It enhances immune system efficacy and aids in energy production during physical exercise. The 1000 mg dosage is well-considered, and the high quality of the ingredients is evident. This supplement can support a diet plan effectively. |
 Solgar, Taurine, 500 mg, 250 Vegetable Capsules | | |
Reduced hypertension symptoms Most Useful Review 1 people found this helpful Excellent! My mother has been enduring hypertension for quite some time. Recently, horse racing episodes have increased. She started taking taurine, which halted the races, and she has also reduced her antihypertensive medication. Taurine acts as a mild antihypertensive, particularly beneficial for younger individuals. Positive impact noted Most Useful Review Taurine has a positive effect on oedema, heart-related issues, hypertension, and hypoglycaemia. It enhances overall immunity. |
 NOW Foods, Double Strength Taurine, 1,000 mg, 250 Veg Capsules | | |
Effective against hypertension Most Useful Review I take it alongside hawthorn extract. It works well for the onset of hypertension. My pressure began to fluctuate recently, but with this remedy, I've managed without pills so far. Convenient dosage Most Useful Review 4 people found this helpful I like taking one tablet in the morning and one in the afternoon to combat hypertension. The dosage is convenient, and I appreciate the slight diuretic effect. Highly recommended! |
 Life Extension, Optimized Quercetin, 250 mg, 60 Vegetarian Capsules | | |
Effective for hypertension Most Useful Review 2 people found this helpful Quercetin reduces the risk of chronic vascular diseases and normalises permeability. As someone who takes it daily alongside Now Foods Bromelain, I've noticed it significantly helps manage my husband's high blood pressure, keeping it below 150 (it used to be 160/100). The addition of quercetin for hypertension has been beneficial. Improves vascular health Most Useful Review 2 people found this helpful Quercetin is excellent for the vessels of both the brain and peripheral organs. Its powerful antioxidant effects have been demonstrated in animals, showing that it protects the brain, heart, and other tissues from oxidative stress. Quercetin helps lower blood pressure for those suffering from hypertension and can significantly improve vascular health. I recommend taking it regularly, and adding FISETIN may provide additional benefits. |
 NOW Foods, Quercetin with Bromelain, 120 Veg Capsules | | |
Good for family health Most Useful Review I have been using this product for several months in cycles of two months with breaks. Quercetin greatly affects overall well-being. I shared it with my mother and sister, both suffering from periodic blood hypertension. After a month of regular intake, they said their blood pressure issues significantly improved. I personally don’t have that issue, but I take quercetin for its anti-aging and anti-inflammatory effects. Recommended for Covid-19 Most Useful Review Quercetin effectively reduces the risk of chronic vascular diseases and normalises their permeability. In cases of hypertension, it helps lower blood pressure. Current recommendations suggest adding quercetin to treatment regimens for Covid-19 at a dosage of 250-500 mg daily, as it serves as a zinc ionophore, potentially inhibiting the replication of SARS-CoV-2. |
 NOW Foods, Selenium, 100 mcg, 100 Tablets | | |
Supports cardiovascular health Most Useful Review 9 people found this helpful Selenium is a microelement that carries out crucial functions in the body. It is essential for hormones and enzymes, protects cells from damage, and helps prevent ageing processes. It's vital for maintaining the beauty and health of skin, hair, and nails, as well as being necessary for arrhythmia, coronary heart disease, hypertension, and atherosclerosis. Selenium aids in fat metabolism and cholesterol regulation, protecting blood vessels and heart muscle from harm, while also reducing the risk of developing hypertension. We are pleased with the quality; I recommend it! Excellent quality supplement Most Useful Review 7 people found this helpful Selenium plays a key role in the body, aiding antioxidant systems and the hormonal function of the thyroid gland. It normalises fat metabolism and cholesterol levels, protects blood vessels and heart muscle, and decreases the risk of hypertension. Additionally, it strengthens blood vessels and has anti-inflammatory effects, while supporting the endocrine system and muscle cell regeneration. The Bud supplement is of high quality, with an excellent composition. |
 Life Extension, Super Selenium Complex & Vitamin E, 200 mcg, 100 Vegetarian Capsules | | |
Positive health trend Most Useful Review 3 people found this helpful The selenium from the reputable American company Life Extension has impressed me. They have been dedicated to health-related research since 1980. Their products, including this selenium complex, appeal to me because of their scientific basis. I trust their formulation as it contains three forms of selenium and vitamin E to enhance absorption. At 55, with hypertension and other conditions, my endocrinologist recommended selenium. Since starting this supplement, I've noticed improvements in my thyroid hormone tests, lowered blood pressure, and a steadier heart rate. Furthermore, I also take vitamin D3, Omega, and coenzyme Q10. Effective blood pressure control Most Useful Review 3 people found this helpful Selenium, best consumed with vitamin E, is essential for various heart conditions, including hypertension. It's usually prescribed for a month, taking one tablet daily. It supports recovery post-myocardial infarction and helps normalise fat metabolism and cholesterol levels in the blood. Additionally, it protects blood vessels and the heart muscle, reducing the risk of developing hypertension. This supplement is excellent quality and highly effective. |
 NOW Foods, Selenium, 200 mcg, 180 Veg Capsules | | |
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 NOW Foods, Flax Oil, 1,000 mg, 100 Softgels | | |
Lowers blood pressure Most Useful Review One of the main advantages of flaxseed oil is its high Omega-3 content, essential for brain cells. I’ve found that consuming it on an empty stomach reduces cholesterol levels, while it has additional benefits like improving blood pressure and preventing hypertension. Reduces hypertension risk Most Useful Review Flaxseed oil lowers the level of harmful cholesterol, strengthens vascular walls, and enhances vessel elasticity. This positively impacts blood pressure, thereby reducing the risk of cardiovascular diseases such as thrombosis, hypertension, and stroke. |
 NOW Foods, Olive Leaf Extract, 500 mg, 120 Veg Capsules | | |
Regulates pressure Most Useful Review 3 people found this helpful Masthav In Viral Time is part of many antiviral drugs, such as Averol. Besides its antiviral properties, olive leaves are beneficial for hypertension, acting as a diuretic and preventing atherosclerosis and obesity. Its use decreases blood pressure, stimulates digestion, and regulates sugar and cholesterol levels. Strengthens immunity Most Useful Review 2 people found this helpful An excellent antivirus tool. I have purchased it several times and am very pleased with the results. The herpes virus and others are weakened and cease activity under the influence of olive leaf extract. My immune system is strengthened. It also has anti-inflammatory effects, aids with hypertension, and improves blood sugar levels. |
 Gaia Herbs, Olive Leaf, 680 mg, 60 Vegan Liquid Phyto-Caps | | |
Recommended treatment Most Useful Review 1 people found this helpful It is recommended to fight against hypertension. Disease prevention Most Useful Review 4 people found this helpful A very useful drug! The oleuropein in olive oil gives it antioxidant and anti-inflammatory properties. Olive leaves are abundant in oleuropein, making the extract a valuable nutrient source. Research indicates olive leaf extracts may help prevent diseases such as hypertension, heart disease, diabetes, cancer, stroke, Alzheimer's disease, and arthritis. |
 Citrucel, Methylcellulose Fiber Therapy for Irregularity, 180 Fiber Caplets | | |
Calmed anxiety Most Useful Review 276 people found this helpful Magnesium B6 is a fantastic aid for my mother who has hypertension. Under stress, our bodies react by raising blood pressure. With a regimen from our neurologist, including Magnesium B6 and a vitamin B complex, my mother has become calmer and more joyful, reminiscent of her youth. Her blood pressure has stabilised as well. This magnesium significantly improves her condition, alleviating anxiety and insomnia. For those in the early stages of hypertension, it can normalise blood pressure effectively without additional medications. Stabilised pressure Most Useful Review 11 people found this helpful This drug has been a real blessing for my mother, who has a history of hypertension and stroke. Recommended by a naturopath, it effectively thins the blood and reduces the risk of clotting. My mother experienced swift relief—her dizziness, headaches, and tinnitus have disappeared, and her blood pressure has stabilised without fluctuations or crises for a month now. This is fantastic progress for her! I've noticed no side effects, and her overall health and energy levels have significantly improved. |
 NOW Foods, Astragalus Extract, 500 mg, 90 Veg Capsules | | |
Positive for hypertension Most Useful Review 10 people found this helpful Astragalus restores strength during heavy mental and physical stress, increases immunity, effectively slows down the ageing process, and rejuvenates. It enhances cerebral circulation and tissue respiration of the brain. It has diuretic, hypotensive, and sedative effects, improves heart function, and dilates cardiac and renal vessels. Notably, it positively impacts the course of hypertension. Supports hypertension treatment Most Useful Review 1 people found this helpful Astragalus demonstrates diuretic, hypotensive, and sedative effects. It significantly improves heart function and dilates the heart and kidney vessels. This infusion positively influences the course of hypertension and is sometimes used as additional treatment. |
 NOW Foods, Sunflower Lecithin, 1,200 mg, 200 Softgels | | |
Cholesterol and liver support Most Useful Review 1 people found this helpful I was hesitant to try lecithin, but it significantly helped me after my tests showed high cholesterol levels. It’s crucial for liver restoration and low cholesterol, thus reducing heart disease and hypertension risk. Combining it with quality Omega supplements enhances its effectiveness. With age or stress, lecithin is essential for maintaining brain function and overall health, particularly for the nervous and cardiovascular systems. Positive liver effects Most Useful Review 1 people found this helpful This product is exceptional! The natural ingredients and superb taste, especially in capsule form, are fantastic. It's been effective for issues like hypertension and other ailments. Lecithin restores liver cells, enhances lipid metabolism, and improves blood vessel function. It's a beneficial addition to anyone's health arsenal, especially for hypertension sufferers. Thank you for this incredible product! |
 Doctor's Best, Extra Strength Ginkgo, 120 mg, 360 Veggie Caps | | |
Focus improvement Most Useful Review 2 people found this helpful I ordered Ginkgo to enhance cerebral blood flow due to my longstanding hypertension. Since beginning the pills, I've woken with a clearer mind. The noise and migraines have ceased, and I feel my memory and concentration have significantly improved. It's vital for my daily routine. Supports overall health Most Useful Review 1 people found this helpful Ginkgo biloba extract offers many health benefits and is effective for hypertension, diabetes, and atherosclerosis. It influences various vitamins that support the nervous system. I've taken it for a month, and though my memory has improved, concentration has sharpened greatly. |