Magnesium
8
We investigated the potential benefits of magnesium in the form of a new compound, magnesium biotin (MgB), on remyelination in rats with induced demyelination. This is particularly relevant for conditions like multiple sclerosis (MS), where demyelination plays a critical role in disease progression. Through our study, we compared MgB's effects to those of standard biotin.
Our findings revealed that MgB significantly enhanced the remyelination process compared to biotin alone. Both treatments showed a dose-dependent improvement in spatial memory, indicating benefits for cognitive functions. Additionally, MgB treatment led to reduced levels of inflammatory proteins, an effect that was more pronounced at higher doses.
Notably, we discovered that MgB helped restore important proteins involved in neuronal function and transmission, such as Synapsin-1 and PSD-95, which are crucial for healthy brain functioning. We also observed an increase in beneficial brain-derived factors and a notable reduction in markers of reactive gliosis, which suggests a reduction in harmful inflammation.
The evidence indicates that combining magnesium with biotin could provide a more effective treatment strategy for promoting myelin repair in demyelination-driven conditions like MS. Our results support the potential for further research into using MgB in clinical settings for MS patients.
Our findings revealed that MgB significantly enhanced the remyelination process compared to biotin alone. Both treatments showed a dose-dependent improvement in spatial memory, indicating benefits for cognitive functions. Additionally, MgB treatment led to reduced levels of inflammatory proteins, an effect that was more pronounced at higher doses.
Notably, we discovered that MgB helped restore important proteins involved in neuronal function and transmission, such as Synapsin-1 and PSD-95, which are crucial for healthy brain functioning. We also observed an increase in beneficial brain-derived factors and a notable reduction in markers of reactive gliosis, which suggests a reduction in harmful inflammation.
The evidence indicates that combining magnesium with biotin could provide a more effective treatment strategy for promoting myelin repair in demyelination-driven conditions like MS. Our results support the potential for further research into using MgB in clinical settings for MS patients.
9
Migraine relief
Most Useful Review
25 people found this helpful
The migraine has resolved! I previously took magnesium aspartate, but due to its neurotoxic effects, I switched to magnesium malate, taking it several times a day. Alongside magnesium chloride baths, transdermal magnesium oil, and sublingual bitter, I suffered from severe migraines for years. Now, I no longer require painkillers. It turns out I was deficient in magnesium.
B12
9
We delved into the relationship between dietary patterns and multiple sclerosis (MS) to uncover the potential influence of folate on the condition. The study utilized genetic data from large-scale genome-wide association studies, particularly focusing on dietary habits and their connection to MS risk and severity.
Our findings indicated that an increased intake of folic acid may play a beneficial role in reducing both the risk and severity of MS. Specifically, genetically predicted higher folic acid intake was associated with a lower risk of developing MS and a decline in its severity. This suggests that incorporating more folate-rich foods into our diets could help with MS management.
However, it’s essential to note that the study didn't isolate folate from other dietary components. As a result, while we observed a positive correlation between folate and MS outcomes, we can’t confidently conclude that folate alone is the deciding factor in these improvements. Nevertheless, these insights could guide future dietary recommendations for those at risk of or managing MS.
Our findings indicated that an increased intake of folic acid may play a beneficial role in reducing both the risk and severity of MS. Specifically, genetically predicted higher folic acid intake was associated with a lower risk of developing MS and a decline in its severity. This suggests that incorporating more folate-rich foods into our diets could help with MS management.
However, it’s essential to note that the study didn't isolate folate from other dietary components. As a result, while we observed a positive correlation between folate and MS outcomes, we can’t confidently conclude that folate alone is the deciding factor in these improvements. Nevertheless, these insights could guide future dietary recommendations for those at risk of or managing MS.
9
Improved mood
Most Useful Review
I have been taking B12 for six months and have noticed I am more balanced, less aggressive, less anxious, and much cheerier. I sleep better now, all thanks to B12, which strengthens the nervous system. It is vital for individuals with autoimmune diseases. I have multiple sclerosis and will need it for life! Cheers to Ayherb for this vitamin.
Dha
7
Cognitive improvements in MS diets
We explored the impact of diet, particularly the intake of essential fatty acids like docosahexaenoic acid (DHA), on cognitive function in individuals with relapsing-remitting multiple sclerosis (MS). A well-structured trial involving 77 participants put two diets to the test: a modified paleolithic diet and a low saturated fat diet. Through assessments at multiple time points, we aimed to understand how these dietary changes affect both serum fatty acid profiles and cognitive abilities.
Our findings revealed that both diets led to significant improvements in cognitive function as measured by tasks such as the Symbol Digit Modalities Test. Notably, we observed that changes in the omega-3 index, which includes DHA, correlated with enhancements in cognitive performance.
It's important to highlight, however, that while these diets seemed effective at boosting overall cognitive function and altering serum fatty acid profiles, we did not establish that the changes in these fatty acids were responsible for improvements in cognitive measures. In essence, DHA's role, when isolated from other dietary components, requires further investigation to clarify its specific effects on cognitive health in MS.
Our findings revealed that both diets led to significant improvements in cognitive function as measured by tasks such as the Symbol Digit Modalities Test. Notably, we observed that changes in the omega-3 index, which includes DHA, correlated with enhancements in cognitive performance.
It's important to highlight, however, that while these diets seemed effective at boosting overall cognitive function and altering serum fatty acid profiles, we did not establish that the changes in these fatty acids were responsible for improvements in cognitive measures. In essence, DHA's role, when isolated from other dietary components, requires further investigation to clarify its specific effects on cognitive health in MS.
7.5
Myelin sheath support
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23 people found this helpful
Excellent! DHA plays an important role in the omega-3 chain and aids in maintaining the myelin sheath, which is crucial for nerve impulse conduction. As a person with multiple sclerosis, preserving my myelin sheath is vital, and DHA is beneficial. NOW's DHA is cost-effective, offers a generous quantity for the price, and has good quality. The capsule size may be an issue for some, but it doesn't bother me. If you found my comment helpful, please give it a like.
Omega 3 Fish Oil
7
Eicosapentaenoic acid enhances cognition
We investigated the connection between dietary changes and cognitive performance in people with relapsing-remitting multiple sclerosis (MS). The study involved 77 participants who were tested at different intervals—before and after following either a modified paleolithic (Wahls) diet or a low saturated fat (Swank) diet.
Both dietary approaches led to improvements in essential fatty acids in the participants' blood, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). We observed meaningful enhancements in cognitive function, as measured by specific tests, especially at the 12 and 24-week marks.
Notably, we found that the change in omega-3 levels, which include EPA and DHA, was associated with improvements in cognitive scores. This means that while both diets positively influenced cognitive abilities, the increases in these fatty acids were a crucial element of this improvement.
Overall, our findings suggest that eicosapentaenoic acid, as part of a broader dietary approach, can play a significant role in enhancing cognitive function for those affected by MS, although further research is needed to clarify the specific impact of EPA alone.
Both dietary approaches led to improvements in essential fatty acids in the participants' blood, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). We observed meaningful enhancements in cognitive function, as measured by specific tests, especially at the 12 and 24-week marks.
Notably, we found that the change in omega-3 levels, which include EPA and DHA, was associated with improvements in cognitive scores. This means that while both diets positively influenced cognitive abilities, the increases in these fatty acids were a crucial element of this improvement.
Overall, our findings suggest that eicosapentaenoic acid, as part of a broader dietary approach, can play a significant role in enhancing cognitive function for those affected by MS, although further research is needed to clarify the specific impact of EPA alone.
9
Excellent quality
Most Useful Review
1 people found this helpful
I've been using this for many years without interruption, despite having multiple sclerosis. The quality is excellent and unmatched by any competitor.
Vitamin D
8
We explored the potential impact of Vitamin D supplementation on patients newly diagnosed with Multiple Sclerosis (MS). Our study involved 16 drug-naïve patients who were monitored over a year. We measured the levels of 25-hydroxy-vitamin D in their blood and evaluated how this vitamin affects the balance between pro-inflammatory and anti-inflammatory cytokines, which play significant roles in MS.
Our findings showed that these patients initially had low vitamin D levels and high levels of pro-inflammatory cytokines. Over the course of the study, participants who received vitamin D supplementation demonstrated a notable decrease in pro-inflammatory cytokine levels. Additionally, the ratio of pro-inflammatory to anti-inflammatory cytokines improved, suggesting that vitamin D may help shift the immune response towards a more protective profile.
Interestingly, while some patients also received immunotherapy, our data indicated that Vitamin D supplementation might independently contribute to better immune regulation. Patients with higher pro-inflammatory cytokine ratios appeared more susceptible to relapses, emphasizing the potential role of Vitamin D in managing MS symptoms.
This research supports the idea that having adequate levels of Vitamin D could be vital for those facing MS, as it may offer a protective mechanism through improving immune responses. Ultimately, vitamin D supplementation could be an essential component of a comprehensive treatment plan for MS patients.
Our findings showed that these patients initially had low vitamin D levels and high levels of pro-inflammatory cytokines. Over the course of the study, participants who received vitamin D supplementation demonstrated a notable decrease in pro-inflammatory cytokine levels. Additionally, the ratio of pro-inflammatory to anti-inflammatory cytokines improved, suggesting that vitamin D may help shift the immune response towards a more protective profile.
Interestingly, while some patients also received immunotherapy, our data indicated that Vitamin D supplementation might independently contribute to better immune regulation. Patients with higher pro-inflammatory cytokine ratios appeared more susceptible to relapses, emphasizing the potential role of Vitamin D in managing MS symptoms.
This research supports the idea that having adequate levels of Vitamin D could be vital for those facing MS, as it may offer a protective mechanism through improving immune responses. Ultimately, vitamin D supplementation could be an essential component of a comprehensive treatment plan for MS patients.
9
Immunity boost
Most Useful Review
235 people found this helpful
One capsule daily ensures my immunity is robust against viral diseases. After regular vitamin D3 intake for several years, not a single cold was caught by my family. As someone with a thyroid condition, this supplement is essential; vitamin D deficiency is often linked with Hashimoto's thyroiditis and multiple sclerosis.
Probiotics
8
We explored how Lactobacillus and Bifidobacterium from traditional dairy might help with multiple sclerosis. In a study with 48 male rats, we induced demyelination and then supplemented with various lactic acid bacteria.
The results were promising! The bacteria helped reduce behavioral deficits, oxidative stress, and demyelination. Additionally, we noticed an increase in important vitamins D and B levels.
While more research is needed, these findings suggest a possible new avenue for treating demyelinating disorders like multiple sclerosis.
The results were promising! The bacteria helped reduce behavioral deficits, oxidative stress, and demyelination. Additionally, we noticed an increase in important vitamins D and B levels.
While more research is needed, these findings suggest a possible new avenue for treating demyelinating disorders like multiple sclerosis.
7.5
Improved wellness
Most Useful Review
I started using these probiotic capsules daily to enhance my digestive and immune health. After a month, I noticed significant improvement in my digestive regularity, and my occasional stomach discomfort had lessened. My energy levels felt more stable throughout the day. The capsules are easy to take with meals, and I appreciate the multiple probiotic strains included. At a reasonable price, they offer a straightforward, effective way to boost the good bacteria in my gut. I will continue taking them for overall wellness.
Alpha Lipoic Acid
9
Numbness reduction
Most Useful Review
126 people found this helpful
I would like to add to my review. Having taken alpha lipoic acid for several years since my multiple sclerosis diagnosis, I noticed the numbness in my hands has eased and completely vanished after six months. The capsules are easy to swallow, and the quality is excellent. I wish all good health.
9
Numbness vanished
Most Useful Review
15 people found this helpful
I have been taking alpha lipoic acid for several years. Diagnosed with multiple sclerosis, I found that the numbness in my hands has lessened and ultimately disappeared after six months. The manufacturer is reliable, and the quality is commendable. Wishing everyone good health!
Acetyl L Carnitine
9
Promotes recovery
Most Useful Review
1 people found this helpful
On my doctor's advice, I have used this to maintain my health and recover from multiple sclerosis episodes, and it has been fantastic.
7.5
Helps with fatigue
Most Useful Review
1 people found this helpful
Excellent! As someone with multiple sclerosis, I find this supplement beneficial for both fatigue and concentration. After a few weeks of taking it, I feel that it has positively impacted me to some degree.
L Lysine
9
Effectively combats herpes
Most Useful Review
Working! My husband was initially sceptical about my purchases from i-herb, but when he sensed the onset of herpes, he promptly requested the magic pill. After taking two doses overnight, there was no trace by morning. For assurance, I continued with one pill daily for a few extra days. I've tested this product several times, and it works remarkably well!
7.5
Prevents herpes outbreaks
Most Useful Review
These are fantastic for keeping herpes viruses at bay and are effective against multiple types. I find the 500 mg size small enough to swallow easily, unlike the larger 1 gram size. Additionally, NOW is a reputable brand.
Multivitamins
9
Decreased fatigue
Most Useful Review
3 people found this helpful
This has greatly helped with my fatigue from multiple sclerosis! I face Chronic Fatigue daily, and with a Vitamin D deficiency, I need all the assistance I can get. I've found that this B50, taken mid-morning, helps me maintain focus and alertness until mid-afternoon. I would recommend it to anyone, especially those with a chronic illness.
7.5
Improved quality of life
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20 people found this helpful
Excellent! This is one of the supplements I continuously order. After my diagnosis of multiple sclerosis in 2011, my quality of life was lacking. I spent years trying to find solutions to normalise my metabolic processes and reduce infections, which has led to a stable remission. Through listening to my body and adjusting my diet, I found B-50, which became an additional source of B vitamins. I take it in short courses and at the first signs of respiratory illnesses, and it helps me avoid getting sick.
Selenium
9
Essential for health
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2 people found this helpful
Selenium is crucial and can effectively alleviate acute pancreatitis. The recommended dosage is 200 mcg, which relieves pancreatic attacks, leading to recovery in three days if combined with fasting. However, taking over 400 mcg daily can be toxic. Selenium also reduces cancer incidence by 40% and acts as an immunomodulator and antioxidant. A deficiency may compromise the body's defence against various diseases, including asthma, oncology, rheumatism, and cardiovascular issues. Furthermore, it helps eliminate toxic metals such as lead and mercury. Low glutathione levels may indicate selenium deficiency, which could also link to sclerosis.
7.5
Reduced trembling
Most Useful Review
Wonderful! I spent three months taking this supplement for my multiple sclerosis. The trembling in my hand completely ceased with the addition of selenium. However, I experienced increased fatigue once I stopped taking it, though my strength improved later. While mielin generally worked well, I am still figuring out its interaction with gluten. Melatonin was effective for a while, helping me sleep at night, but eventually, it stopped being effective.
Inositol
9
Boosts energy levels
Most Useful Review
9 people found this helpful
Gives vigour and strength! Since I began taking this choline with inositol, I immediately felt a surge of vitality, which I hadn't experienced for a long time due to multiple sclerosis. My mood improved significantly! It's a pity I didn't discover this sooner. Now, I plan to take it regularly in courses. Wishing everyone good health!
7.5
Calming effects noted
Most Useful Review
I purchased this on my doctor's recommendation for my multiple sclerosis. I've noticed an increase in my calmness, which I believe the choline supplement facilitated. The dosage is sufficient for a prolonged period.
Collagen Supplements
9
Painkiller elimination
Most Useful Review
3 people found this helpful
I took this supplement for two months based on my rheumatologist's advice, alongside medicinal treatments and vitamin D (I have unspecified reactive arthropathy). The results have been remarkable; I've managed to completely stop using painkillers. However, it’s important to note that collagen might be detrimental if you have rheumatic conditions such as systemic scleroderma or systemic sclerosis. Therefore, consulting a doctor before use is essential.
7.5
Knee support
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1 people found this helpful
I've had issues with my left knee for nearly 15 years, trying various supplements without success. After starting UC-II four months ago, I recently went on a month-long trip with several hikes. My knee felt fine throughout, with only slight soreness on one challenging day. I plan to continue with this supplement as it appears to be working wonders for me!
Vitamin B Complex
9
Improved well-being
Most Useful Review
2 people found this helpful
I've experienced fatigue issues due to multiple sclerosis, but since taking Solgar B-Complex for three months, I feel much better.
8
Energy boost
Most Useful Review
The vitamin B complex supplement has noticeably improved my well-being. It provides a range of B vitamins that meet various health needs. The pills are appropriately sized, and I appreciate the freshness of the packaging. I've noticed an increase in energy and mood, making it beneficial for daily health and during stressful periods.
N Acetyl Glucosamine
7.5
Calmness experienced
Most Useful Review
83 people found this helpful
I drink with multiple sclerosis and have observed its effects on myself. My head has calmed down, and I believe N-acetylglucosamine (NAG) supports the body in restoring myelin membranes—assuming the body has enough building materials. I take LECITHIN alongside NAG and vitamin B6, which aids in myelin construction. If this review was helpful, please let me know. 👍🏼
9
Improved sensory function
Most Useful Review
12 people found this helpful
I purchase this for an adult with multiple sclerosis. I read studies indicating that this amino acid aids in restoring nerve connections in laboratory animals. With limited alternatives apart from symptomatic treatments, we decided to try it. After one month, sensitivity in the fingers returned, and we observed clearer speech and increased energy, along with overall positive effects. I ordered a second jar.
Ginkgo Biloba
7.5
Clarity of mind
Most Useful Review
4 people found this helpful
I purchased this for my mother, who is of a respectable age and suffers from multiple sclerosis. She needs to take it regularly to improve her memory and brain circulation. After a month of use, she says the effects are better than from a similar pharmacy product. I observed a remarkable clarity of thought previously clouded by frequent mental fog. The one-tablet dosage is a bonus, and it's a safe composition for regular use. I will update my review in six months.
9
General health improvement
Most Useful Review
3 people found this helpful
The quality of the brand and ingredients is superb. At 40, I've managed my multiple sclerosis with these supplements. The results have been outstanding. I never go without ginkgo, which significantly benefits my brain function, memory, and energy. Overall, my health has improved, and I suggest it to anyone with similar health challenges – just consult your doctor beforehand.
Melatonin
9
Game changer experience
Most Useful Review
Excellent product; I couldn't recommend it more highly. I have ordered these multiple times and they have significantly changed my sleep pattern. After taking them, I find it much easier to fall asleep and wake up feeling refreshed, which is something I cannot achieve without them. I take 2 tablets about 30 minutes before bed, and I sleep like a baby.
7.5
Restful sleep achieved
Most Useful Review
Great product! I have bought it multiple times, and it ensures a restful sleep. I find it most effective when taken right before bedtime, as it begins to wear off quickly.