Inositol
8
We examined how Myo-inositol, a natural compound, influences prostate cancer cells, specifically the DU-145 cell line. The study aimed to evaluate its potential as a treatment by determining how it affects cell survival and protein expression.
To do this, we treated the DU-145 cells with varying doses of Myo-inositol and assessed cell viability using a method called the trypan blue exclusion assay. Our findings showcased that Myo-inositol significantly decreased cell viability, with an IC50 value of 0.06 mg/ml, indicating that it could hinder cancer cell growth effectively.
Moreover, we explored the changes in protein expression brought about by Myo-inositol treatment. Our proteomic analysis revealed notable differences in the proteins expressed in treated cells compared to untreated ones. There were key alterations in proteins associated with preventing cell death and managing stress, suggesting that Myo-inositol might engage in important cancer-fighting pathways.
Overall, our results suggest that Myo-inositol exhibits considerable anticancer effects on prostate cancer cells. Although it shows promise as a supplementary treatment, we stress the need for further research to unveil the precise mechanisms of action and explore its potential in combination therapies for advanced prostate cancer.
To do this, we treated the DU-145 cells with varying doses of Myo-inositol and assessed cell viability using a method called the trypan blue exclusion assay. Our findings showcased that Myo-inositol significantly decreased cell viability, with an IC50 value of 0.06 mg/ml, indicating that it could hinder cancer cell growth effectively.
Moreover, we explored the changes in protein expression brought about by Myo-inositol treatment. Our proteomic analysis revealed notable differences in the proteins expressed in treated cells compared to untreated ones. There were key alterations in proteins associated with preventing cell death and managing stress, suggesting that Myo-inositol might engage in important cancer-fighting pathways.
Overall, our results suggest that Myo-inositol exhibits considerable anticancer effects on prostate cancer cells. Although it shows promise as a supplementary treatment, we stress the need for further research to unveil the precise mechanisms of action and explore its potential in combination therapies for advanced prostate cancer.
9
Cancer management support
Most Useful Review
7 people found this helpful
I have been taking IP6 for four years after my cancer operation. My initial outlook was grim, but following a friend's recommendation, I continued taking them. I’m still cancer-free, so I’ll keep using them as a precaution.
Zinc
8
We explored the relationship between zinc levels and prostate cancer treatments, particularly focusing on a novel compound known as 3D. This compound showed a strong potential to target prostate cancer cells, contributing to a decrease in their proliferation rates.
Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.
We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.
Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
Our analysis revealed that compound 3D selectively impacted key metabolic processes in prostate cancer cells by suppressing factors related to energy production, such as lactate levels. Interestingly, it also reduced the activity of transporters involved in zinc absorption while leaving those responsible for zinc export untouched.
We also found that the effectiveness of 3D could be reversed with zinc treatment, highlighting a complicated interaction between zinc and this therapeutic approach. While the compound successfully lowered zinc levels in cells and inhibited cancer growth, it is essential to note that we did not find significant benefits from zinc treatment by itself in the context of this study.
Overall, our findings suggest that targeting zinc metabolism and enhancing heme oxygenase-1 expression could be a promising strategy in prostate cancer therapy, more so than the direct application of zinc itself. The results illustrate the potential for combining innovative small molecules with an understanding of cancer metabolism in the development of treatment strategies.
9
Pain relief
Most Useful Review
13 people found this helpful
With chronic prostatitis, this supplement has become my top choice. I experience less pain and improved sperm quality, and zinc has increased my free testosterone levels. I highly recommend it to anyone dealing with issues related to prostate cancer.
Vitamins
8
We aimed to understand the role of vitamin D in treating prostate cancer, a serious disease that affects many men worldwide. The study highlights the problematic nature of advanced prostate cancer treatments, as most patients can develop resistance to standard hormone and chemotherapy options.
Our research showed a clear connection between low levels of vitamin D and the severity of prostate cancer, as well as the reduced presence of its receptor in prostate cells. This prompted us to investigate the effects of a vitamin D analog specifically in a mouse model designed for prostate cancer.
We observed that using this vitamin D analog positively impacted the tumor microenvironment in these mice. Moreover, we found that combining this vitamin D treatment with a common chemotherapy drug, docetaxel, helped overcome resistance observed in primary prostate cancer spheroids and in patient-derived xenografts that were resistant to both docetaxel and androgen deprivation.
Thus, our findings indicate that vitamin D analogs could be a promising new strategy for tackling advanced prostate cancer, offering hope for improving treatment outcomes for patients facing this challenging disease.
Our research showed a clear connection between low levels of vitamin D and the severity of prostate cancer, as well as the reduced presence of its receptor in prostate cells. This prompted us to investigate the effects of a vitamin D analog specifically in a mouse model designed for prostate cancer.
We observed that using this vitamin D analog positively impacted the tumor microenvironment in these mice. Moreover, we found that combining this vitamin D treatment with a common chemotherapy drug, docetaxel, helped overcome resistance observed in primary prostate cancer spheroids and in patient-derived xenografts that were resistant to both docetaxel and androgen deprivation.
Thus, our findings indicate that vitamin D analogs could be a promising new strategy for tackling advanced prostate cancer, offering hope for improving treatment outcomes for patients facing this challenging disease.
9
Enhances sexual health
Most Useful Review
7 people found this helpful
This product has numerous benefits, including improving sperm health, increasing sexual desire, and aiding in achieving erections. Vitamin D3 may help prevent prostate cancer and also promotes bone and joint health. Understanding these benefits makes one fortunate.
Pumpkin Seeds Pepitas
8
We conducted a study to assess how a combination of fuzuloparib, a PARP inhibitor, and abiraterone, an androgen receptor inhibitor, can affect localized high-risk prostate cancer. In this phase 2 trial involving 35 treatment-naive men, participants received six cycles of the therapy followed by radical prostatectomy.
We aimed to measure the effectiveness of this combination therapy by evaluating two main outcomes: pathological complete response (pCR) and minimal residual disease (MRD). The results were promising, showing a combined pCR/MRD rate of 46%, indicating that nearly half of the patients had no detectable disease after treatment. Additionally, 53% of participants remained free of biochemical progression two years post-treatment.
Interestingly, we found that specific molecular alterations, particularly involving biallelic homologous recombination repair and BRCA2 genes, were tied to quicker declines in prostate-specific antigen levels, which is a key marker for prostate cancer. Genomic analyses done after treatment revealed a reduction in MYC amplification and growth markers, suggesting that the therapy effectively targeted aggressive cancer attributes.
However, it’s important to note that about 23% of patients encountered grade ≥3 adverse events, highlighting some risks associated with this treatment. Overall, this study demonstrated the potential of combining these therapies in treating prostate cancer while establishing a foundation for exploring various biomarkers that could inform future research.
We aimed to measure the effectiveness of this combination therapy by evaluating two main outcomes: pathological complete response (pCR) and minimal residual disease (MRD). The results were promising, showing a combined pCR/MRD rate of 46%, indicating that nearly half of the patients had no detectable disease after treatment. Additionally, 53% of participants remained free of biochemical progression two years post-treatment.
Interestingly, we found that specific molecular alterations, particularly involving biallelic homologous recombination repair and BRCA2 genes, were tied to quicker declines in prostate-specific antigen levels, which is a key marker for prostate cancer. Genomic analyses done after treatment revealed a reduction in MYC amplification and growth markers, suggesting that the therapy effectively targeted aggressive cancer attributes.
However, it’s important to note that about 23% of patients encountered grade ≥3 adverse events, highlighting some risks associated with this treatment. Overall, this study demonstrated the potential of combining these therapies in treating prostate cancer while establishing a foundation for exploring various biomarkers that could inform future research.
9
Prostate cancer protection
Most Useful Review
Rich in iron and protein, I consume a handful of pumpkin seeds between meals. They also contain zinc, selenium, kelp, and copper, which I believe help protect my prostate cancer.
Selenium
9
We sought to understand how selenium, specifically in the form of lentinan-functionalized selenium nanoparticles (LET-SeNPs), can improve radiotherapy outcomes for prostate cancer. Our investigation showed that when these nanoparticles were combined with X-ray therapy, they significantly hampered the growth of prostate cancer cells and their ability to form colonies. This effect was greater than either treatment alone.
The mechanism behind this enhanced sensitivity involved a complex interplay of cellular pathways. We observed that LET-SeNPs helped induce more robust apoptosis, or programmed cell death, by targeting various signaling routes in the cancer cells, such as the p53, MAPK, and AKT pathways. Moreover, they elevated levels of reactive oxygen species (ROS), which are known to promote apoptosis, while also decreasing the expression of Thioredoxin reductase, an enzyme that aids in DNA repair.
In animal models, the combination therapy proved effective in slowing down tumor growth, reinforcing our findings from the lab. These results suggest that using LET-SeNPs alongside X-ray therapy could potentially transform prostate cancer treatment, enhancing its effectiveness while possibly reducing side effects. Overall, we believe that selenium-modified nanoparticles hold significant promise for advancing cancer therapies.
The mechanism behind this enhanced sensitivity involved a complex interplay of cellular pathways. We observed that LET-SeNPs helped induce more robust apoptosis, or programmed cell death, by targeting various signaling routes in the cancer cells, such as the p53, MAPK, and AKT pathways. Moreover, they elevated levels of reactive oxygen species (ROS), which are known to promote apoptosis, while also decreasing the expression of Thioredoxin reductase, an enzyme that aids in DNA repair.
In animal models, the combination therapy proved effective in slowing down tumor growth, reinforcing our findings from the lab. These results suggest that using LET-SeNPs alongside X-ray therapy could potentially transform prostate cancer treatment, enhancing its effectiveness while possibly reducing side effects. Overall, we believe that selenium-modified nanoparticles hold significant promise for advancing cancer therapies.
9
Cancer prevention
Most Useful Review
136 people found this helpful
Selenium is an essential supplement for preventing cancer. To maintain my health and reduce tumour risks, I believe this supplement is crucial.
Turmeric Curcumin
8
We explored the challenges surrounding curcumin, a compound found in turmeric known for its antioxidant and anti-inflammatory properties, particularly in the context of treating prostate cancer. The study aimed to improve its effectiveness by creating a specialized carrier, a microorganism-metal-organic framework, designed to enhance curcumin's solubility and stability.
Our research demonstrated that this new composite carrier, when loaded with curcumin, significantly increased the compound's delivery efficiency. We observed that the enhanced formulation was able to reduce the viability of prostate cancer cells dramatically—by around 50%—at a concentration of 20 µM after 48 hours of treatment.
Moreover, through our analysis of gene expression related to apoptosis, we found that the composite effectively induced cell death in cancer cells—a key goal in cancer therapies. This suggests that curcumin, when properly delivered, can have a powerful antitumor effect, presenting promising potential for future prostate cancer treatments. Ultimately, our findings highlight the importance of improving drug delivery systems for enhancing the therapeutic possibilities of natural compounds like curcumin in prostate cancer care.
Our research demonstrated that this new composite carrier, when loaded with curcumin, significantly increased the compound's delivery efficiency. We observed that the enhanced formulation was able to reduce the viability of prostate cancer cells dramatically—by around 50%—at a concentration of 20 µM after 48 hours of treatment.
Moreover, through our analysis of gene expression related to apoptosis, we found that the composite effectively induced cell death in cancer cells—a key goal in cancer therapies. This suggests that curcumin, when properly delivered, can have a powerful antitumor effect, presenting promising potential for future prostate cancer treatments. Ultimately, our findings highlight the importance of improving drug delivery systems for enhancing the therapeutic possibilities of natural compounds like curcumin in prostate cancer care.
9
Stronger antioxidant
Most Useful Review
23 people found this helpful
Curcumin is known for its powerful anti-cancer actions and strong antioxidant properties. I prefer the Drs. Best 1000 mg caplets over the Jarrow formula for affordability and take it twice daily.
D Mannose
8
We explored how polysaccharides extracted from Yunnan Tratt fruits affect prostate cancer DU145 cells. Our study investigated their ability to inhibit cell proliferation, migration, and invasion, along with their role in inducing apoptosis.
We utilized various methods, including assays for cell viability and migration, as well as flow cytometry to assess the effects on the cell cycle. The results revealed that Tratt polysaccharides can indeed suppress the growth of DU145 cells while promoting cell death through changes in important proteins and genes.
We utilized various methods, including assays for cell viability and migration, as well as flow cytometry to assess the effects on the cell cycle. The results revealed that Tratt polysaccharides can indeed suppress the growth of DU145 cells while promoting cell death through changes in important proteins and genes.
9
Nearly eliminated UTIs
Most Useful Review
4 people found this helpful
This product has been a lifesaver after facing severe complications from prostate cancer surgery, leading to recurring UTIs. Despite trying various remedies, D-Mannose has almost eradicated my UTIs, and my surgeon fully supports its use. I take two 500mg capsules nightly and have reduced UTI occurrences by about 95%.
Broccoli
8
Sulforaphane's potential in prostate cancer
We explored the role of sulforaphane, a compound from broccoli, in combating prostate cancer. This review spans various studies that assess how sulforaphane can potentially hinder the development and progression of prostatic tumors, utilizing methods ranging from in vitro, in vivo, to clinical settings.
While many findings suggest its promising protective effects, our analysis highlighted some limitations and the need for further research to fully understand its therapeutic potential. Overall, more work is needed before sulforaphane can be firmly established as an effective treatment option.
While many findings suggest its promising protective effects, our analysis highlighted some limitations and the need for further research to fully understand its therapeutic potential. Overall, more work is needed before sulforaphane can be firmly established as an effective treatment option.
7.5
Slowed cancer growth
Most Useful Review
10 people found this helpful
While I cannot be certain, since using this product, the growth rate of my prostate cancer seems to have significantly slowed.
Ascorbic Acid
4
We investigated how vitamin C, also known as ascorbic acid (ASC), interacts with prostate cancer cells under different conditions. Our focus was on the influence of oxygen levels and iron availability on the effectiveness of ASC against various prostate cancer cell lines, such as PC-3, DU 145, LNCaP, and CWR22Rv1.
Interestingly, we found that low oxygen conditions, or hypoxia, actually increased the amount of ASC needed to show cytotoxic effects in these cancer cells. However, this effect was not seen in normal prostate cells, which suggests that the cancer cells have unique responses to their environment. We also tested the synthetic androgen dihydrotestosterone, a common factor in prostate cancer, but it did not change how effective ASC was in either low or normal oxygen levels.
When we looked at the broader impact of hypoxia, we discovered that it did not alter the effectiveness of the DNA-damaging drug etoposide but did reduce the effectiveness of the anti-microtubule agent paclitaxel in certain cancer lines. Despite observing that hypoxic cells were low in iron, adding iron back into the cells did not restore sensitivity to ASC. In fact, we noted that the concentration of ASC needed to be higher in iron-treated PC-3 cells compared to those without iron.
Overall, our findings indicate that both hypoxia and iron levels can diminish the therapeutic effectiveness of high doses of vitamin C in prostate cancer cells. This highlights the complexity of using vitamin C as a treatment, as these environmental factors might impact its potential benefits for patients with prostate cancer.
Interestingly, we found that low oxygen conditions, or hypoxia, actually increased the amount of ASC needed to show cytotoxic effects in these cancer cells. However, this effect was not seen in normal prostate cells, which suggests that the cancer cells have unique responses to their environment. We also tested the synthetic androgen dihydrotestosterone, a common factor in prostate cancer, but it did not change how effective ASC was in either low or normal oxygen levels.
When we looked at the broader impact of hypoxia, we discovered that it did not alter the effectiveness of the DNA-damaging drug etoposide but did reduce the effectiveness of the anti-microtubule agent paclitaxel in certain cancer lines. Despite observing that hypoxic cells were low in iron, adding iron back into the cells did not restore sensitivity to ASC. In fact, we noted that the concentration of ASC needed to be higher in iron-treated PC-3 cells compared to those without iron.
Overall, our findings indicate that both hypoxia and iron levels can diminish the therapeutic effectiveness of high doses of vitamin C in prostate cancer cells. This highlights the complexity of using vitamin C as a treatment, as these environmental factors might impact its potential benefits for patients with prostate cancer.
10
Life-saving vitamins
Most Useful Review
After consuming these vitamins, two cancer patients are now leading normal lives. They played a crucial role in their recovery.
Nettle
7
We explored how 3,4-divanillyltetrahydrofuran (DTH), derived from Urtica dioica roots, affects prostate cancer cells with varying androgen sensitivity. Using advanced techniques, we radiolabeled DTH to understand its uptake in two types of prostate cancer cells: LNCaP, which is androgen-sensitive, and PC3, which is not.
Our findings revealed that DTH exhibited a higher toxicity towards LNCaP cells compared to PC3 cells. While the study uncovers potential roles of DTH in treating certain prostate cancer types, it emphasizes the need for further research to fully understand its effectiveness.
Our findings revealed that DTH exhibited a higher toxicity towards LNCaP cells compared to PC3 cells. While the study uncovers potential roles of DTH in treating certain prostate cancer types, it emphasizes the need for further research to fully understand its effectiveness.
9
Effective choice
Most Useful Review
19 people found this helpful
This product supports prostate cancer health well. My husband finds it beneficial and it has improved his condition.
Omega 3 Fish Oil
2
We conducted a phase II double-blind, randomized placebo-controlled trial to understand the effects of a dietary supplement called MAG-EPA, which is rich in eicosapentaenoic acid (EPA), on prostate cancer. Involving 130 men diagnosed with grade group 2 or higher prostate cancer, we aimed to see if this omega-3 fatty acid could effectively slow down cancer growth.
Participants were randomly assigned to take either 3 grams of MAG-EPA daily or a placebo for 7 weeks before undergoing radical prostatectomy. The main measure of our study was the cancer proliferation index, which we assessed by analyzing tumor samples for a specific protein known as Ki-67.
Unfortunately, our findings showed that MAG-EPA did not significantly change the rate of cancer proliferation as indicated by Ki-67 expression. While we did gather additional information on inflammatory cytokines and fatty acid profiles, the lack of any observable benefits from the MAG-EPA treatment stands out.
This study illuminates the complexities of dietary supplements like omega-3 fatty acids in cancer treatment. Further research is essential to better understand their potential impact on prostate cancer, but for now, we found no evidence to suggest that MAG-EPA is effective in reducing cancer growth.
Participants were randomly assigned to take either 3 grams of MAG-EPA daily or a placebo for 7 weeks before undergoing radical prostatectomy. The main measure of our study was the cancer proliferation index, which we assessed by analyzing tumor samples for a specific protein known as Ki-67.
Unfortunately, our findings showed that MAG-EPA did not significantly change the rate of cancer proliferation as indicated by Ki-67 expression. While we did gather additional information on inflammatory cytokines and fatty acid profiles, the lack of any observable benefits from the MAG-EPA treatment stands out.
This study illuminates the complexities of dietary supplements like omega-3 fatty acids in cancer treatment. Further research is essential to better understand their potential impact on prostate cancer, but for now, we found no evidence to suggest that MAG-EPA is effective in reducing cancer growth.
7.5
Effective Omega supplement
Most Useful Review
I have been taking NOW Brand Omega 3-6-9 for 18 years, but due to being prescribed Tamoxifen after breast cancer, I had to stop all but Omega 3. I switched to these capsules, and they are nearly as good as the 3-6-9 blend. I plan to return to the 3-6-9 once I finish Tamoxifen.
Coenzyme Q10 Coq10
We systematically reviewed various lifestyle interventions, including dietary and nutritional changes, aimed at influencing prostate cancer progression and mortality. Among the interventions we examined were trials that integrated coenzyme Q10, often alongside other supplements like lycopene and selenium.
Notably, the trials incorporating coenzyme Q10 were part of a larger group of 44 randomized controlled studies involving a total of 3,418 prostate cancer patients from 13 countries. Although some trials showed beneficial effects on disease outcomes, the specific impact of coenzyme Q10 was hard to isolate, as it was paired with other supplements in the trials.
The results indicated that while several combinations yielded promising outcomes, many trials suffered from limitations such as small sample sizes, high risk of bias, or inadequate reporting, which prevent us from definitively concluding that coenzyme Q10 alone is effective against prostate cancer. In summary, we found that more robust, well-structured trials focusing on coenzyme Q10 would be necessary to clarify its role and effectiveness.
Notably, the trials incorporating coenzyme Q10 were part of a larger group of 44 randomized controlled studies involving a total of 3,418 prostate cancer patients from 13 countries. Although some trials showed beneficial effects on disease outcomes, the specific impact of coenzyme Q10 was hard to isolate, as it was paired with other supplements in the trials.
The results indicated that while several combinations yielded promising outcomes, many trials suffered from limitations such as small sample sizes, high risk of bias, or inadequate reporting, which prevent us from definitively concluding that coenzyme Q10 alone is effective against prostate cancer. In summary, we found that more robust, well-structured trials focusing on coenzyme Q10 would be necessary to clarify its role and effectiveness.
8
Increased energy focus
Most Useful Review
Doctor’s Best High Absorption CoQ10 with BioPerine is superb! I've noted increased energy, improved focus, and reduced mental fog. It enhances my overall wellbeing and supports my body. CoQ10 is an antioxidant that defends against free radical damage while BioPerine may help combat the growth of cancer cells and aids nutrient absorption.
Quercetin
9
Recommended brand
Most Useful Review
17 people found this helpful
My doctor, a leading oncologist, has recommended Jarrow brand as part of my treatment for prostate cancer. He says Jarrow is the brand that most accurately represents what’s on its label.
7.5
Positive treatment outcome
Most Useful Review
9 people found this helpful
My spouse has been using this quercetin for over a year as part of her breast cancer treatment, guided by Dr. Belkin's recommendations. Alongside Curcumin 95, we believe it contributes positively to her treatment progress.
Resveratrol
9
Improved prostate levels
Most Useful Review
2 people found this helpful
My father purchased this to help with my prostate cancer, and after taking it, my levels have significantly improved.
7.5
Fighting cancer support
Most Useful Review
1 people found this helpful
Without hesitation, I bought my favourite Now Foods product, 'Resveratrol,' as recommended in a cancer-fighting book. I intend to continue using it for my health.
Childrens Herbs
9
Quick recovery noted
Most Useful Review
I give it to my children for prostate cancer symptoms, and they recover quickly.
9
Effective for cold
Most Useful Review
Absolutely brilliant! I give my child 0.5 ml every two days for symptoms of prostate cancer, and it effectively ends the cold.
Kelp
9
New lease on life
Most Useful Review
4 people found this helpful
Adding iodine, along with vitamin D3, can significantly improve one's wellbeing. Iodine aids in revitalising the thyroid and combats the negative effects of exposure to radon and other natural radiation. This supplement is particularly beneficial if there is a family history of issues like breast or prostate cancer. I appreciate that LifeExtension has been trusted by health professionals for many years.
7.5
Prostate health support
Most Useful Review
I'm pleased with the quality of these iodine capsules, which are the perfect size. Iodine is often difficult to obtain through diet, making this supplement an essential addition for maintaining prostate health.
Probiotics
9
Severe inflammation relief
Most Useful Review
Praise be! I benefited from this prostate supplement during my struggle with severe inflammation.
7.5
Prostate support recommended
Most Useful Review
9 people found this helpful
Young people recommend this for chronic prostate inflammation. It pairs excellently with prostate support pills, especially after an antibiotic course.
Fiber
7.5
Reduced hot flushes
Most Useful Review
6 people found this helpful
My husband receives hormone injections every three months for his secondary prostate cancer. He takes three Ultimate-E gelcaps daily and is pleased with the reduction in hot flushes.
9
Powerful treatment
Most Useful Review
Excellent product. This herb is among the most powerful for treating prostate cancer and I appreciate its effectiveness.
Boron
9
Multi-beneficial mineral
Most Useful Review
Boron has significantly benefited my prostate, joints, and bones, making it an excellent choice for overall health.
7.5
Prostate function improved
Most Useful Review
3 people found this helpful
This is an excellent supplement; I use it regularly and have noticed significant improvements in my prostate health.
Saw Palmetto
9
Highly recommended herb
Most Useful Review
This fragrant product is crucial for addressing prostate problems; it is, without doubt, the best herb for this issue. I strongly recommend it.
9
Effective prostate support
Most Useful Review
Products based on this plant are acknowledged as highly effective for maintaining prostate health and addressing sexual dysfunction in men.