Hyaluronic Acid
9
Novel RA treatment strategy explored
This study explored the potential of a new hyaluronic acid-modified nanocatalyst designed to treat rheumatoid arthritis (RA). The research aimed to manipulate immune cells in the body, specifically altering macrophage polarization and combating oxidative stress.
Through lab tests and experiments on mice, we found that the nanocatalyst effectively reduced joint inflammation and improved cartilage health. It also promoted a shift from harmful to protective immune responses. Overall, these findings suggest a promising approach to enhance RA treatment, combining multiple beneficial actions in one strategy.
Through lab tests and experiments on mice, we found that the nanocatalyst effectively reduced joint inflammation and improved cartilage health. It also promoted a shift from harmful to protective immune responses. Overall, these findings suggest a promising approach to enhance RA treatment, combining multiple beneficial actions in one strategy.
10
Prescription-Free Relief
Most Useful Review
14 people found this helpful
A few years ago, I was diagnosed with Rheumatoid Arthritis and prescribed medications. However, after a friend's recommendation, I started taking Hyaluronic Acid. Since then, I’ve stopped taking my prescription drugs! I can hardly believe the difference it has made to how I feel. I absolutely love it and can't thank you enough!
Folic Acid
9
Folic acid-modified vesicles tackle RA
This study presents an innovative approach to tackling rheumatoid arthritis (RA) using folic acid-modified ginger-derived extracellular vesicles (FA-GDEVs). We explored how these tiny vesicles, enriched with bioactive compounds from ginger, can be directed toward inflamed joints by utilizing folic acid to target specific immune cells.
Initially, we investigated the ability of FA-GDEVs to shift the balance of macrophages from the harmful M1 type, which fuels inflammation, to the more healing M2 type. Our findings revealed that FA-GDEVs effectively influence this transition by activating related pathways within the cells.
In practical terms, this means that FA-GDEVs can not only find their way to affected areas more efficiently but also work to reduce signs of RA while maintaining a good safety profile. Ultimately, these ginger-derived vesicles could be a more affordable and safer option for RA treatment, marking a significant advancement in how we approach this chronic condition.
Initially, we investigated the ability of FA-GDEVs to shift the balance of macrophages from the harmful M1 type, which fuels inflammation, to the more healing M2 type. Our findings revealed that FA-GDEVs effectively influence this transition by activating related pathways within the cells.
In practical terms, this means that FA-GDEVs can not only find their way to affected areas more efficiently but also work to reduce signs of RA while maintaining a good safety profile. Ultimately, these ginger-derived vesicles could be a more affordable and safer option for RA treatment, marking a significant advancement in how we approach this chronic condition.
9
High-quality supplement
Most Useful Review
Excellent! This is perfect for anyone with immune conditions. My mother has rheumatoid arthritis, and this supplement should not be split; its quality is outstanding.
Vitamins
8
Calcitriol improves immune function in RA
We investigated how calcitriol, a form of vitamin D3, influences the immune response in rheumatoid arthritis (RA). In this study, rheumatoid arthritis was induced in BALB/c mice, allowing us to assess the effectiveness of calcitriol-treated mesenchymal stem cells (MSCs) compared to untreated ones. This involved dividing the mice into three groups: one without treatment, one receiving untreated MSCs, and the last treated with calcitriol-exposed MSCs.
Our findings showed that calcitriol treatment significantly improved the regulatory functions of immune cells, particularly splenocytes. In particular, we observed enhanced safety and reduced levels of inflammatory mediators associated with RA. Furthermore, the production of cytokines like IL-4, IL-10, and TGF-β increased, while INF-γ and IL-17 levels decreased in animals treated with calcitriol. This suggests that vitamin D3 could play a promising role in moderating the immune response in RA patients.
Overall, our study highlights the potential of calcitriol in creating effective treatment pathways for rheumatoid arthritis, addressing existing challenges in managing this chronic inflammatory condition.
Our findings showed that calcitriol treatment significantly improved the regulatory functions of immune cells, particularly splenocytes. In particular, we observed enhanced safety and reduced levels of inflammatory mediators associated with RA. Furthermore, the production of cytokines like IL-4, IL-10, and TGF-β increased, while INF-γ and IL-17 levels decreased in animals treated with calcitriol. This suggests that vitamin D3 could play a promising role in moderating the immune response in RA patients.
Overall, our study highlights the potential of calcitriol in creating effective treatment pathways for rheumatoid arthritis, addressing existing challenges in managing this chronic inflammatory condition.
9
Increased immunity
Most Useful Review
2 people found this helpful
I have taken Vitamin D three times now for my rheumatoid arthritis. A high dose has significantly helped me. The quality is excellent and the quantity lasts a considerable time. This high dosage boosts immunity. It’s tasteless and very effective.
Glucosamine Chondroitin Formulas
4
In our clinical trial, we investigated the effects of methylsulfonylmethane (MSM) combined with boswellic acids (BA) on individuals suffering from knee arthritis, a chronic condition often characterized by joint pain and inflammation. We enrolled 60 participants who were randomly divided into two groups: one group received the MSM and BA treatment for 60 days, and the other group was given a placebo.
Over the follow-up periods of 2 and 6 months, we measured pain levels using a visual analog scale (VAS) and assessed joint function with the Lequesne index (LI). While we found that participants taking MSM and BA reported higher pain levels than those on the placebo after 2 months, these differences did not persist at the 6-month mark. Furthermore, when evaluating joint function, we noted no significant differences between the two groups.
However, one notable finding was that those receiving the combination treatment needed fewer anti-inflammatory drugs compared to the placebo group at both follow-up points. Despite the reduced reliance on these medications, we concluded that combined treatment with MSM and BA did not significantly improve pain or joint function compared to placebo.
Over the follow-up periods of 2 and 6 months, we measured pain levels using a visual analog scale (VAS) and assessed joint function with the Lequesne index (LI). While we found that participants taking MSM and BA reported higher pain levels than those on the placebo after 2 months, these differences did not persist at the 6-month mark. Furthermore, when evaluating joint function, we noted no significant differences between the two groups.
However, one notable finding was that those receiving the combination treatment needed fewer anti-inflammatory drugs compared to the placebo group at both follow-up points. Despite the reduced reliance on these medications, we concluded that combined treatment with MSM and BA did not significantly improve pain or joint function compared to placebo.
7.5
Significant improvement
Most Useful Review
250 people found this helpful
There is an effect - it works! I delayed writing a review as I wanted to observe the results. I ordered this drug for my mother-in-law, who has rheumatoid arthritis, and for my mother, suffering from intervertebral disc issues. Initially sceptical, they began taking the drug when pain forced them to agree. Within ten days, my mother-in-law noticed it was easier to rise from a chair, and the swelling in her knees diminished, though pain persisted. After two weeks, my mother could wake up on her side, something she hadn't managed due to back pain. They have now been taking the drug for over a month, and I'm reordering. They recommend it!
Collagen Supplements
8
We investigated the effects of GSZD, a traditional decoction, on bone erosion in a rat model of rheumatoid arthritis. Fifty rats were divided into control and treatment groups. Over 21 days, those receiving GSZD showed improved signs of inflammation and reduced joint damage compared to controls.
Specifically, GSZD lowered osteoclast numbers and enhanced protective factors, indicating its potential as a treatment option for rheumatoid arthritis. This study suggests GSZD could serve as a valuable supplement in managing RA symptoms.
Specifically, GSZD lowered osteoclast numbers and enhanced protective factors, indicating its potential as a treatment option for rheumatoid arthritis. This study suggests GSZD could serve as a valuable supplement in managing RA symptoms.
7.5
Knees stopped hurting
Most Useful Review
122 people found this helpful
I began taking collagen on my rheumatologist's advice due to my rheumatoid arthritis. After 10 days, my knees stopped hurting and my hands felt easier. While miracles don’t happen and damaged joints can't be restored, at least my mobility has improved. If you have joint pain, don’t delay treatment! I highly recommend it!
Evening Primrose Oil
8
We examined how supplementation with marine omega-3 fatty acids and evening primrose oil (rich in GLA) could help relieve rheumatoid arthritis symptoms in a randomized trial of 60 patients.
After 12 weeks, those taking either fish oil alone or in combination with evening primrose oil showed remarkable improvements in joint pain and disease activity compared to those who received no supplements.
This suggests that these oils may significantly benefit people dealing with the inflammation and discomfort of rheumatoid arthritis.
After 12 weeks, those taking either fish oil alone or in combination with evening primrose oil showed remarkable improvements in joint pain and disease activity compared to those who received no supplements.
This suggests that these oils may significantly benefit people dealing with the inflammation and discomfort of rheumatoid arthritis.
9
Pain relief noted
Most Useful Review
4 people found this helpful
I have been using evening primrose oil for a long while, and I can only share positive experiences. At 52, I started taking it for hot flashes, and it certainly helped. Additionally, it provided relief for my knee problems associated with rheumatoid arthritis. It’s noted that gamma-linolenic acid can alleviate the chronic inflammation pain typical of rheumatoid arthritis, making this oil a valuable addition to my routine.
Omega 3 Fish Oil
7
We aimed to uncover how dietary factors, particularly omega 3-rich oily fish, influence the risk of rheumatoid arthritis (RA). Using a robust Mendelian randomization analysis, we assessed data from large genome-wide studies.
Our findings indicated that higher intake of oily fish is associated with a lower risk of RA, along with cereal consumption. However, we didn't find significant protective effects from other dietary factors. This suggests that RA patients and those at higher risk may benefit from dietary adjustments, especially with increased oily fish intake.
Our findings indicated that higher intake of oily fish is associated with a lower risk of RA, along with cereal consumption. However, we didn't find significant protective effects from other dietary factors. This suggests that RA patients and those at higher risk may benefit from dietary adjustments, especially with increased oily fish intake.
9
Supports cardiovascular health
Most Useful Review
14 people found this helpful
Omega-3 is vital for preventing conditions like atherosclerosis and regulating cholesterol levels. Recommended doses vary, but significantly higher amounts are suggested for serious health issues, including rheumatoid arthritis. It’s essential to read labels for the EPA and DHA content to ensure you're getting a quality product. This supplement’s properties extend to numerous health benefits and should be taken seriously.
MSM
4
In our clinical trial, we investigated the effects of methylsulfonylmethane (MSM) combined with boswellic acids (BA) on individuals suffering from knee arthritis, a chronic condition often characterized by joint pain and inflammation. We enrolled 60 participants who were randomly divided into two groups: one group received the MSM and BA treatment for 60 days, and the other group was given a placebo.
Over the follow-up periods of 2 and 6 months, we measured pain levels using a visual analog scale (VAS) and assessed joint function with the Lequesne index (LI). While we found that participants taking MSM and BA reported higher pain levels than those on the placebo after 2 months, these differences did not persist at the 6-month mark. Furthermore, when evaluating joint function, we noted no significant differences between the two groups.
However, one notable finding was that those receiving the combination treatment needed fewer anti-inflammatory drugs compared to the placebo group at both follow-up points. Despite the reduced reliance on these medications, we concluded that combined treatment with MSM and BA did not significantly improve pain or joint function compared to placebo.
Over the follow-up periods of 2 and 6 months, we measured pain levels using a visual analog scale (VAS) and assessed joint function with the Lequesne index (LI). While we found that participants taking MSM and BA reported higher pain levels than those on the placebo after 2 months, these differences did not persist at the 6-month mark. Furthermore, when evaluating joint function, we noted no significant differences between the two groups.
However, one notable finding was that those receiving the combination treatment needed fewer anti-inflammatory drugs compared to the placebo group at both follow-up points. Despite the reduced reliance on these medications, we concluded that combined treatment with MSM and BA did not significantly improve pain or joint function compared to placebo.
9
Almost painlessly living
Most Useful Review
7 people found this helpful
Works for rheumatoid arthritis! I’ve been diagnosed with rheumatoid arthritis and have been drinking this product. Maybe the immunomodulator isn't effective and should be increased, but thanks to this, I can live almost painlessly! I believe it’s due to this, as it causes pain in 2-3 days if I don't take it and rely solely on the immunomodulator.
Magnesium
9
Joint pain relief
Most Useful Review
1 people found this helpful
I purchased magnesium on my doctor's advice and am very pleased. I take it alongside D3, K2, and a B-group complex. This combination has effectively reduced my pains from rheumatoid arthritis in my joints and muscles; I've been using it for almost two months now.
10
Sleep enhancement
Most Useful Review
THIS WORKS! I waited until I finished the first bottle before posting this review. Having watched a video on how magnesium can aid sleep, I decided to try it as I often struggle to fall asleep due to my rheumatoid arthritis. During flare-up periods, I feel achy all over. This product has been incredibly helpful; with its muscle-relaxing properties, I now fall asleep before 10 PM. The quality is excellent, and I would absolutely recommend it and repurchase it repeatedly!
Turmeric Curcumin
10
Joint pain relief
Most Useful Review
25 people found this helpful
This product is excellent for managing my joint pain caused by rheumatoid arthritis. I am very pleased with it and highly recommend it.
9
Pain relief achieved
Most Useful Review
10 people found this helpful
High-quality turmeric from the renowned brand Himalaya serves as an anti-inflammatory agent, particularly for joints. It alleviated pain associated with rheumatoid arthritis and reduced swelling in my hands. I took it for two months consecutively and plan to repeat the course in six months. I highly recommend it!
Topical Ointments
10
Remarkable relief
Most Useful Review
10 people found this helpful
To me, it's just one word: superb! I have rheumatoid arthritis and I am 43. Two months ago, my elbows began to swell and became painful to bend—so much so that I could not rub my head with my left hand. I remembered that a few years ago I ordered a New Food liposome lotion for a friend and decided it was time to try it myself. The result was like magic; just two applications yesterday and today, and I regained the use of my arms. I can hardly believe it! Thank God and thank you, iHerb and Now Foods!
7.5
Effective MSM cream
Most Useful Review
2 people found this helpful
I developed rheumatoid arthritis and tried various treatments; MSM has proven effective for me. This product was sold out, so while using other MSM creams, I noticed it was restocked. I bought it immediately. Initially, I was a bit concerned about the smell, but I actually liked it. As it contains arnica, there's a warning regarding long-term use and sensitivity for skin.
Bromelain
9
Pain relief achieved
Most Useful Review
25 people found this helpful
Best supplement for joint pain. I take Bromelain, Serrapeptase, and Nattokinase three times daily, away from food. They have become essential in my battle with Rheumatoid arthritis. The quality, size, and dosage of these products are excellent. After a couple of weeks, my pain disappeared. I wholeheartedly recommend them; you'll soon notice the benefits and regain a normal life.
7.5
Effective post-infection
Most Useful Review
2 people found this helpful
A brilliant preparation for working with blood vessels and acting as an anti-inflammatory nutraceutical. I have Rheumatoid arthritis, an autoimmune disease, and have found it essential to rely on nutraceuticals. Following a coronavirus infection which caused bilateral lung inflammation, this drug containing quercetin has been tremendously helpful.
Multivitamins
9
Effective for mother
Most Useful Review
8 people found this helpful
I regularly purchase this drug for my mother (69, suffering from rheumatoid arthritis for over 15 years). She is very pleased; the effect surpasses sulfasalazine, which caused severe side effects. She takes it for 2 months on, 2 months off (but continues Boswelia separately) for nearly 2 years. The effect was noticeable by the 7th day of first use. Now, her small joints, especially in her hands, are less inflamed and painful. However, it does not change existing joint deformities.
9
Genuine improvement noted
Most Useful Review
3 people found this helpful
I was diagnosed with rheumatoid arthritis, and after six months on pharmaceutical chondroprotectors to no avail, I decided to try Animal Flex as recommended. Within 3-5 days, I experienced significant improvement; my hands and fingers stopped hurting. This supplement truly works and contains all essential nutrients for effective absorption of chondroitin and glucosamine. I have chosen to stick with Animal Flex moving forward.
Pectin
9
Effective treatment
Most Useful Review
3 people found this helpful
Helps with rheumatoid arthritis. A colleague at elementary school had a high RA index, nearly qualifying for a major injury card. He introduced me to apple pectin, as recommended by Dr. Gu Xiaopei, who described its ability to produce butyrate, beneficial for autoimmunity. Since then, his index has significantly dropped, and he has been diagnosed with rheumatoid arthritis, eliminating the need for injections. It’s truly remarkable.
7.5
Significant improvement
Most Useful Review
Apple Pectin and Niacin have greatly improved several types of rheumatoid arthritis after following this diet for six years.
Nettle
7.5
Effective pain relief
Most Useful Review
2 people found this helpful
The nettle plant is very beneficial for alleviating pain and reducing inflammation. It comes in two forms: roots, which are believed to be more effective for pain compared to the leaves, both having their advantages. I took the roots to ease the pain and inflammation associated with rheumatoid arthritis, consuming 3 capsules daily. I found it effective in relieving my pain as mentioned. For those seeking further information, Nada Harfoush discusses it on YouTube, and Dr. Berg alongside Karim also elaborated on its natural ingredients, quality, appropriate dosage, and herbal scent.
9
Very effective relief
Most Useful Review
1 people found this helpful
Excellent! This is the fourth pack I’ve used for rheumatoid arthritis, and it effectively alleviates pain.
Enzymes
9
Pain relief
Most Useful Review
34 people found this helpful
I’m taking nattokinase along with serrapeptase and bromelain three times a day away from food, and they have become my best allies in managing rheumatoid arthritis. The quality, size, and dosage of these products are excellent. After a few weeks of use, my pain vanished. I wholeheartedly recommend them; you will soon notice the benefits and reclaim your normal life.
9
Promotes good health
Most Useful Review
30 people found this helpful
Help with arthritis! High-quality serrapeptase without taste or odour. The convenient dosage—1 capsule in the morning and evening on an empty stomach—takes effect after a month. I've used various brands for ten years, and with rheumatoid arthritis, this has kept me healthy! I highly recommend it as a natural alternative to pharmaceuticals.
Selenium
9
Combats deficiencies
Most Useful Review
Selenium is crucial for the immune system and has potent antioxidant and anticancer effects. Individuals with Rheumatoid arthritis often experience selenium deficiency, which can affect their immune response. I found that taking selenium alongside vitamin E enhances its benefits. Although the effects might take some time to manifest, ensuring adequate selenium levels is vital for overall health, particularly for the thyroid. It’s also effective in supporting individuals battling metal poisoning and has aided in my overall well-being.
9
Effective pain relief
Most Useful Review
After being diagnosed with Rheumatoid arthritis, I decided to try selenium as a supplement to alleviate pain. Remarkably, within four days, I began to notice positive effects. This vitamin has contributed significantly to reducing my discomfort and improving my overall health, showing that targeted supplementation can make a meaningful difference in managing symptoms associated with Rheumatoid arthritis.
Fiber
7.5
Significant improvement
Most Useful Review
250 people found this helpful
There is an effect - it works! I delayed writing a review as I wanted to observe the results. I ordered this drug for my mother-in-law, who has rheumatoid arthritis, and for my mother, suffering from intervertebral disc issues. Initially sceptical, they began taking the drug when pain forced them to agree. Within ten days, my mother-in-law noticed it was easier to rise from a chair, and the swelling in her knees diminished, though pain persisted. After two weeks, my mother could wake up on her side, something she hadn't managed due to back pain. They have now been taking the drug for over a month, and I'm reordering. They recommend it!
9
Life-changing supplement
Most Useful Review
37 people found this helpful
Fantastic miracle supplement for arthritis sufferers! I have Rheumatoid arthritis in my wrists, knees, and sometimes my back. I've been taking Jarrow and Now brands Curcumin for months. I don’t take painkillers, but Curcumin has made my life manageable with significantly less pain and flare-ups. Someone suggested trying the Bio or Super form of Curcumin from Now brands for even better results. To this day, it's a miracle supplement for arthritis like mine, and I now feel almost pain-free. I take one capsule in the morning and one before bed. It energises me, but be cautious with exercise as it can lead to acute pain if overdone. Thanks, iHerb for great prices and fresh supplements.
Boron
9
Bloating relief
Most Useful Review
11 people found this helpful
I began taking boron for my rheumatoid arthritis. There appears to be a connection between soil nutrient deficits and arthritis prevalence. However, what truly compels me to continue taking boron is the complete disappearance of my bloating, pain, and cramps. I used to experience severe symptoms before my period, but now nothing. I suggested it to my daughter, and she's also had similar benefits within two weeks; she's committed to taking it as well. We’re certainly spreading the word!
8
Joint improvement
Most Useful Review
7 people found this helpful
I requested boron multiple times due to the noticeable improvement in my joints and exercise capability. I increased the dose to two pills daily, as those who exercise should take 6mg. The ingredients are excellent and the value is satisfactory. Boron is crucial for bone health and enhances the absorption of vitamin D, calcium, and magnesium, beneficial for conditions like osteoporosis and rheumatoid arthritis. Moreover, it bolsters antioxidant production, protects against several cancers, and aids in hormone regulation. It’s a rare mineral, and I find it difficult to get enough without supplementation.
Childrens Herbs
7.5
Reduces inflammation
Most Useful Review
Preparations containing echinacea assist in reducing systemic inflammation in rheumatoid arthritis and uveitis, which is inflammation of the eye's vascular membrane. Due to its anti-inflammatory and immunomodulatory effects, echinacea can combat upper respiratory tract diseases like asthma.
7.5
Systemic inflammation relief
Most Useful Review
Preparations containing echinacea aid in diminishing systemic inflammation in rheumatoid arthritis and uveitis, the inflammation of the vascular membrane of the eye. Owing to its anti-inflammatory and immunomodulatory properties, echinacea is effective against upper respiratory tract diseases like asthma.
Cat Claw
9
Quality of life restored
Most Useful Review
5 people found this helpful
I purchased this after extensive research on homeopathic solutions for managing rheumatoid arthritis. Having previously dealt with autoimmune issues, I was desperate for effective relief. After just four days of adding these supplements, my lower back pain disappeared, and my hands and feet felt considerably less stiff. I’m genuinely astonished by the rapid improvement in my quality of life!
7.5
Inflammation reduction
Most Useful Review
5 people found this helpful
This product has effectively reduced my inflammation from rheumatoid arthritis.