Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.9
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Blend Containing 1 billion live cultures† Lactobacillus acidophilus Lactobacillus salivarius Bifidobacterium bifidum Streptococcus thermophilus
175 mg
**
Top Medical Research Studies
9
This study explored how soymilk fermented with Lactococcus acidophilus influenced cardiovascular health in rats on a high-fat diet. We found that the fermented soymilk effectively reduced harmful lipid levels and improved antioxidant enzyme activity.
Notably, it significantly lowered indicators of arterial and coronary health risks compared to traditional hypolipidemic drugs. The results suggest that incorporating fermented soymilk may offer a natural way to support heart health and alleviate hyperlipidemia.
Notably, it significantly lowered indicators of arterial and coronary health risks compared to traditional hypolipidemic drugs. The results suggest that incorporating fermented soymilk may offer a natural way to support heart health and alleviate hyperlipidemia.
Read More
8
Probiotics may enhance cardiovascular health
We explored the impact of probiotic supplementation on cardiovascular health in patients with type-2 diabetes. In a double-blind, controlled trial, participants took probiotics or placebo for six weeks.
After this period, we observed notable improvements in various cardiovascular parameters, including blood pressure and key atherogenic indices. This suggests that probiotics might help lower the risk of future cardiovascular disease in those living with diabetes.
However, we recognize that more research is necessary to fully understand these benefits.
After this period, we observed notable improvements in various cardiovascular parameters, including blood pressure and key atherogenic indices. This suggests that probiotics might help lower the risk of future cardiovascular disease in those living with diabetes.
However, we recognize that more research is necessary to fully understand these benefits.
Read More
8
L. acidophilus K301 shows promise
We investigated the impact of Lactobacillus acidophilus K301 on cholesterol regulation and cardiovascular disease. Our findings indicated that this probiotic strain enhances cholesterol transport in macrophages by increasing specific gene expressions linked to cholesterol efflux.
In experiments with mice, we saw a decrease in harmful lipoprotein buildup in arteries, suggesting potential anti-atherosclerotic effects. While these results are promising, further studies are necessary to fully understand how L. acidophilus K301 could be used in cardiovascular disease prevention.
In experiments with mice, we saw a decrease in harmful lipoprotein buildup in arteries, suggesting potential anti-atherosclerotic effects. While these results are promising, further studies are necessary to fully understand how L. acidophilus K301 could be used in cardiovascular disease prevention.
Read More
Most Useful Reviews
9
Effective for inflammation
17 people found this helpful
To enhance my oral health, I purchased this to accompany biotin. After noticing my gums were swollen due to previous tooth decay, I learned Lactobacillus acidophilus could be helpful. I directly applied it to my gums, and the swelling reduced significantly within an hour. It seems quite beneficial for improving and preventing periodontal disease.
Read More
9
Effective for IBS
1 people found this helpful
I've been taking this for a year now. I have a chronic IBS condition and used hospital medicine for recovery over six months. To improve my intestinal environment, I tried about five different lactic acid bacteria supplements, and this one is by far the most effective. It also notably reduces odour in sensitive areas.
Read More
8
Regulated digestion functions
1 people found this helpful
This drug helped significantly in regulating my digestive system functions. Probiotics enhance food digestion, maintain normal acidity levels, boost vitamin production, block pathogenic bacteria growth, and regulate intestinal activity. Thanks to them, my body stimulates the production of immunoglobulins that fight diseases. Additionally, these beneficial microorganisms can help block emerging infections.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
- All Researches
9
This study explored how soymilk fermented with Lactococcus acidophilus influenced cardiovascular health in rats on a high-fat diet. We found that the fermented soymilk effectively reduced harmful lipid levels and improved antioxidant enzyme activity.
Notably, it significantly lowered indicators of arterial and coronary health risks compared to traditional hypolipidemic drugs. The results suggest that incorporating fermented soymilk may offer a natural way to support heart health and alleviate hyperlipidemia.
Notably, it significantly lowered indicators of arterial and coronary health risks compared to traditional hypolipidemic drugs. The results suggest that incorporating fermented soymilk may offer a natural way to support heart health and alleviate hyperlipidemia.
Read More
9
We observed the impact of a special diet, including Lactobacillus acidophilus yogurt and natural antioxidants, on heart health in rats exposed to doxorubicin. Over 22 weeks, various groups of rats received different treatments, including our functional food and a common heart medication.
The results showed that this probiotic-rich food helped normalize heart electrical activity and reduced heart enlargement markers compared to the doxorubicin-only group. It also lowered harmful inflammatory markers and improved beneficial antioxidant levels.
However, while these findings are promising, they are based on animal models and may not directly translate to humans.
The results showed that this probiotic-rich food helped normalize heart electrical activity and reduced heart enlargement markers compared to the doxorubicin-only group. It also lowered harmful inflammatory markers and improved beneficial antioxidant levels.
However, while these findings are promising, they are based on animal models and may not directly translate to humans.
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8
Probiotics’ impact on heart attacks
We designed a study to explore if probiotics can help improve outcomes for patients with acute myocardial infarction. In our open-label trial involving 2,594 patients, we examined the effects of a probiotic capsule containing Lactobacillus acidophilus among others.
Our primary focus was on whether these probiotics could reduce in-hospital mortality and the occurrence of significant cardiovascular events. While the results are still pending, our findings could provide insights into the use of probiotics as a supportive treatment in heart care.
Our primary focus was on whether these probiotics could reduce in-hospital mortality and the occurrence of significant cardiovascular events. While the results are still pending, our findings could provide insights into the use of probiotics as a supportive treatment in heart care.
Read More
8
Probiotics may support heart health
We addressed the intriguing question of how probiotic strains affect cardiovascular health, particularly in cases of systemic inflammatory response syndrome (SIRS). In our study involving rats with obesity and colon inflammation, we found that administering a combination of specific probiotic strains led to a noticeable reduction in heart damage following induced heart attacks.
Our observations indicated improvements in several blood parameters, suggesting a positive influence on heart health. Although we found benefits, more research is essential to fully understand probiotics' role in supporting heart function.
Our observations indicated improvements in several blood parameters, suggesting a positive influence on heart health. Although we found benefits, more research is essential to fully understand probiotics' role in supporting heart function.
Read More
8
Probiotics may enhance cardiovascular health
We explored the impact of probiotic supplementation on cardiovascular health in patients with type-2 diabetes. In a double-blind, controlled trial, participants took probiotics or placebo for six weeks.
After this period, we observed notable improvements in various cardiovascular parameters, including blood pressure and key atherogenic indices. This suggests that probiotics might help lower the risk of future cardiovascular disease in those living with diabetes.
However, we recognize that more research is necessary to fully understand these benefits.
After this period, we observed notable improvements in various cardiovascular parameters, including blood pressure and key atherogenic indices. This suggests that probiotics might help lower the risk of future cardiovascular disease in those living with diabetes.
However, we recognize that more research is necessary to fully understand these benefits.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for inflammation
17 people found this helpful
To enhance my oral health, I purchased this to accompany biotin. After noticing my gums were swollen due to previous tooth decay, I learned Lactobacillus acidophilus could be helpful. I directly applied it to my gums, and the swelling reduced significantly within an hour. It seems quite beneficial for improving and preventing periodontal disease.
Read More
9
Effective for IBS
1 people found this helpful
I've been taking this for a year now. I have a chronic IBS condition and used hospital medicine for recovery over six months. To improve my intestinal environment, I tried about five different lactic acid bacteria supplements, and this one is by far the most effective. It also notably reduces odour in sensitive areas.
Read More
8
Regulated digestion functions
1 people found this helpful
This drug helped significantly in regulating my digestive system functions. Probiotics enhance food digestion, maintain normal acidity levels, boost vitamin production, block pathogenic bacteria growth, and regulate intestinal activity. Thanks to them, my body stimulates the production of immunoglobulins that fight diseases. Additionally, these beneficial microorganisms can help block emerging infections.
Read More
9
Visible improvement
After deciding to improve my health, particularly my skin condition, my dermatologist recommended a course of probiotics alongside other medications. I opted for this acidophilus probiotic blend. I noticed results within a week. I appreciated the large jar, ease of use, and most importantly, the outcome. The capsule size might seem slightly large, but it poses no issue for me.
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7.5
Improved digestive comfort
8 people found this helpful
The product arrived in perfect condition. I opted to refrigerate it since I take it weekly, and it's been beneficial. My boyfriend, who has Crohn's disease, often suffers from gastrointestinal discomfort. With this product, he has experienced considerable relief from his symptoms and gas.
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Frequently Asked Questions
9
Chronic IBS improvement
2 people found this helpful
This is my second repeat purchase. I have chronic IBS and tried various lactic acid bacteria, but I was completely cured in about six months with hospital medicine and this item.
7.5
Supports immunity
5 people found this helpful
Works wonderfully! Acidophilus, a pivotal probiotic, bolsters normal intestinal flora, crucial for immunity. It’s advantageous for dysbiosis and inflammatory gastrointestinal conditions. I recommend taking one capsule 2-3 times daily before meals; I personally take one at night, and my digestive health has been excellent!
7.5
Improved digestive comfort
8 people found this helpful
The product arrived in perfect condition. I opted to refrigerate it since I take it weekly, and it's been beneficial. My boyfriend, who has Crohn's disease, often suffers from gastrointestinal discomfort. With this product, he has experienced considerable relief from his symptoms and gas.
9
Effective for inflammation
17 people found this helpful
To enhance my oral health, I purchased this to accompany biotin. After noticing my gums were swollen due to previous tooth decay, I learned Lactobacillus acidophilus could be helpful. I directly applied it to my gums, and the swelling reduced significantly within an hour. It seems quite beneficial for improving and preventing periodontal disease.
7.5
Great immunity boost
If you consume this, you will notice a signal around 12:30. Good intestinal health boosts your immunity, helping you avoid illnesses. I bought it at a low price, but the effects are remarkable!
6
Relieved constipation
Many people bought this, so I tried it too, but I'm not sure it suits me due to lactose intolerance. However, my father, who suffers from diabetes and cardiovascular disease, found it effective for constipation.
8
Probiotics may enhance cardiovascular health
We explored the impact of probiotic supplementation on cardiovascular health in patients with type-2 diabetes. In a double-blind, controlled trial, participants took probiotics or placebo for six weeks.
After this period, we observed notable improvements in various cardiovascular parameters, including blood pressure and key atherogenic indices. This suggests that probiotics might help lower the risk of future cardiovascular disease in those living with diabetes.
However, we recognize that more research is necessary to fully understand these benefits.
After this period, we observed notable improvements in various cardiovascular parameters, including blood pressure and key atherogenic indices. This suggests that probiotics might help lower the risk of future cardiovascular disease in those living with diabetes.
However, we recognize that more research is necessary to fully understand these benefits.
2
No reduction in cardiovascular risk
We aimed to explore whether a 24-week course of probiotics could improve cardiovascular risk in patients with biopsy-confirmed non-alcoholic steatohepatitis (NASH). In this double-blind, placebo-controlled study, participants received either a probiotic mix or a placebo daily.
After the treatment, we observed no significant reduction in cardiovascular risk markers between the two groups. This indicates that, in this context, probiotics may not be effective for lowering cardiovascular risks in NASH patients.
After the treatment, we observed no significant reduction in cardiovascular risk markers between the two groups. This indicates that, in this context, probiotics may not be effective for lowering cardiovascular risks in NASH patients.
8
Probiotics may protect heart health
We explored the impact of four different probiotics, including Lactobacillus acidophilus, on heart health in a rat model simulating a heart attack. Over two weeks, rats received daily doses of these probiotics before inducing heart injury.
We observed that probiotics reduced harmful toxins and improved heart function. They showed potential in protecting against heart issues by lowering inflammation markers and oxidative stress damage. This suggests probiotics might be a valuable preventive option for those at risk for heart disease in the future.
We observed that probiotics reduced harmful toxins and improved heart function. They showed potential in protecting against heart issues by lowering inflammation markers and oxidative stress damage. This suggests probiotics might be a valuable preventive option for those at risk for heart disease in the future.
References
- Chen Y, Chen R, Wang X, Zhou Y, Hong L, et al. Effect of probiotic supplementation on in-hospital mortality in patients with acute myocardial infarction: a study protocol for an open-label, randomized, controlled, superiority clinical trial. Trials. 2023;24:429. 10.1186/s13063-023-07443-5
- Borshchev YY, Sonin DL, Burovenko IY, Borshchev VY, Cheburkin YV, et al. The Effect of Probiotic Strains on Myocardial Infarction Size, Biochemical and Immunological Parameters in Rats with Systemic Inflammatory Response Syndrome and Polymorbidity. J Evol Biochem Physiol. 2022;58:2058. 10.1134/S0022093022060321
- Barcelos STA, Silva-Sperb AS, Moraes HA, Longo L, de Moura BC, et al. Oral 24-week probiotics supplementation did not decrease cardiovascular risk markers in patients with biopsy proven NASH: A double-blind placebo-controlled randomized study. Ann Hepatol. 2023;28:100769. 10.1016/j.aohep.2022.100769
- Nabhani Z, Clark CCT, Goudarzi N, Hariri Far A, Razmpoosh E. The effect of synbiotic supplementation on atherogenic indices, hs-CRP, and malondialdehyde, as major CVD-related parameters, in women with gestational diabetes mellitus: a secondary data-analysis of a randomized double-blind, placebo-controlled study. Diabetol Metab Syndr. 2022;14:87. 10.1186/s13098-022-00858-1
- Ahmadian F, Razmpoosh E, Ejtahed HS, Javadi M, Mirmiran P, et al. Effects of probiotic supplementation on major cardiovascular-related parameters in patients with type-2 diabetes mellitus: a secondary-data analysis of a randomized double-blind controlled trial. Diabetol Metab Syndr. 2022;14:52. 10.1186/s13098-022-00822-z
- Romão da Silva LF, de Oliveira Y, de Souza EL, de Luna Freire MO, Braga VA, et al. Effects of probiotic therapy on cardio-metabolic parameters and autonomic modulation in hypertensive women: a randomized, triple-blind, placebo-controlled trial. Food Funct. 2020;11:7152. 10.1039/d0fo01661f
- Haghighat N, Mohammadshahi M, Shayanpour S, Haghighizadeh MH. Effect of Synbiotic and Probiotic Supplementation on Serum Levels of Endothelial Cell Adhesion Molecules in Hemodialysis Patients: a Randomized Control Study. Probiotics Antimicrob Proteins. 2019;11:1210. 10.1007/s12602-018-9477-9
- Chen J, Wu Y, Yang C, Xu X, Meng Y. Antioxidant and hypolipidemic effects of soymilk fermented via Lactococcus acidophilus MF204. Food Funct. 2017;8:4414. 10.1039/c7fo00701a
- Farrokhian A, Raygan F, Soltani A, Tajabadi-Ebrahimi M, Sharifi Esfahani M, et al. The Effects of Synbiotic Supplementation on Carotid Intima-Media Thickness, Biomarkers of Inflammation, and Oxidative Stress in People with Overweight, Diabetes, and Coronary Heart Disease: a Randomized, Double-Blind, Placebo-Controlled Trial. Probiotics Antimicrob Proteins. 2019;11:133. 10.1007/s12602-017-9343-1
- Sadeghzadeh J, Vakili A, Sameni HR, Shadnoush M, Bandegi AR, et al. The Effect of Oral Consumption of Probiotics in Prevention of Heart Injury in a Rat Myocardial Infarction Model: a Histopathological, Hemodynamic and Biochemical Evaluation. Iran Biomed J. 2017;21:174.
- Tajabadi-Ebrahimi M, Sharifi N, Farrokhian A, Raygan F, Karamali F, et al. A Randomized Controlled Clinical Trial Investigating the Effect of Synbiotic Administration on Markers of Insulin Metabolism and Lipid Profiles in Overweight Type 2 Diabetic Patients with Coronary Heart Disease. Exp Clin Endocrinol Diabetes. 2017;125:21. 10.1055/s-0042-105441
- Hong YF, Kim H, Kim HS, Park WJ, Kim JY, et al. Lactobacillus acidophilus K301 Inhibits Atherogenesis via Induction of 24 (S), 25-Epoxycholesterol-Mediated ABCA1 and ABCG1 Production and Cholesterol Efflux in Macrophages. PLoS One. 2016;11:e0154302. 10.1371/journal.pone.0154302
- Kalani M, Hodjati H, Sajedi Khanian M, Doroudchi M. Lactobacillus acidophilus Increases the Anti-apoptotic Micro RNA-21 and Decreases the Pro-inflammatory Micro RNA-155 in the LPS-Treated Human Endothelial Cells. Probiotics Antimicrob Proteins. 2016;8:61. 10.1007/s12602-016-9214-1
- Sun J, Buys N. Effects of probiotics consumption on lowering lipids and CVD risk factors: a systematic review and meta-analysis of randomized controlled trials. Ann Med. 2015;47:430. 10.3109/07853890.2015.1071872
- Abu-Elsaad NM, Abd Elhameed AG, El-Karef A, Ibrahim TM. Yogurt Containing the Probacteria Lactobacillus acidophilus Combined with Natural Antioxidants Mitigates Doxorubicin-Induced Cardiomyopathy in Rats. J Med Food. 2015;18:950. 10.1089/jmf.2014.0104
- Tomaro-Duchesneau C, Jones ML, Shah D, Jain P, Saha S, et al. Cholesterol assimilation by Lactobacillus probiotic bacteria: an in vitro investigation. Biomed Res Int. 2014;2014:380316. 10.1155/2014/380316
